43 results on '"Praderio L"'
Search Results
2. TNFRSF1A Mutations in Italian Patients Affected by Apparently Sporadic Periodic Fever Syndrome
- Author
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Palladini, G, primary, Obici, L, additional, Merlini, G, additional, Marciano, S, additional, Lavatelli, F, additional, Tresoldi, M, additional, Donadei, S, additional, Cigni, A, additional, Praderio, L, additional, and Satta, A, additional
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- 2004
- Full Text
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3. TNFRSF1A Mutations in Italian Patients Affected by Apparently Sporadic Periodic Fever Syndrome
- Author
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Obici, L., primary, Marciano, S., additional, Palladini, G., additional, Lavatelli, F., additional, Donadei, S., additional, Cigni, A., additional, Satta, A.E., additional, Praderio, L., additional, Tresoldi, M., additional, and Merlini, G., additional
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- 2004
- Full Text
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4. Juxta-vertebral lesions in granulomatosis with polyangiitis
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Ramirez GA, Della Torre E, Campochiaro C, Bozzolo E, Berti A, Praderio L, Sabbadini M.G., DELLA TORRE , EMANUEL, DAGNA , LORENZO, Ramirez, Ga, Della Torre, E, Campochiaro, C, Bozzolo, E, Berti, A, Praderio, L, Dagna, Lorenzo, Sabbadini, M. G., and DELLA TORRE, Emanuel
- Subjects
musculoskeletal diseases ,Male ,Pathology ,medicine.medical_specialty ,Systemic disease ,Myeloblastin ,Context (language use) ,macromolecular substances ,Serology ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,stomatognathic system ,Rheumatology ,Fluorodeoxyglucose F18 ,Back pain ,Medicine ,Humans ,030212 general & internal medicine ,Pathological ,Aged ,030203 arthritis & rheumatology ,business.industry ,Granulomatosis with Polyangiitis ,Middle Aged ,medicine.disease ,Anesthesiology and Pain Medicine ,Back Pain ,Granuloma ,Positron-Emission Tomography ,Cohort ,Female ,Spinal Diseases ,Radiology ,medicine.symptom ,Radiopharmaceuticals ,business ,Granulomatosis with polyangiitis ,Tomography, X-Ray Computed - Abstract
Abtract Objectives To describe the clinical, pathological, serological, and radiological characteristics of juxta-vertebral masses occurring in patients with granulomatosis with polyangiitis (GPA). Methods We analyzed the clinical records of patients with juxta-vertebral lesions from our GPA study cohort and reviewed the English literature for other cases of GPA with juxta-vertebral localization. Results Out of 74 patients in our GPA study cohort, six (8%) had juxta-vertebral lesions. We found 10 cases of juxta-vertebral GPA described in the English literature. Overall, juxta-vertebral lesions were detected at GPA onset in 11/16 (69%) patients, and preferentially occurred on the right side of the spine (12/15 patients, 80%). Fifteen patients (94%) with juxta-vertebral lesions had systemic GPA. Juxta-vertebral lesions were associated with back pain at GPA onset in 8/16 (50%) patients. In all of them juxta-vertebral lesions resolved or improved after treatment. Conclusions Preference for the right-anterior side of the spine, increased 18 FDG uptake on PET scan, low or absent invasiveness of the surrounding tissues, and occurrence in the context of systemic disease were the main features of juxta-vertebral GPA. Symptomatic lesions showed a better response to immunosuppressive therapies.
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- 2016
5. IgG4-related disease in Italy: clinical features and outcomes of a large cohort of patients
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Campochiaro C, Ramirez GA, Bozzolo EP, Lanzillotta M, Berti A, Baldissera E, Praderio L, Scotti R, Tresoldi M, Roveri L, Mariani A, Balzano G, Castoldi R, Sabbadini MG, Della Torre E., DELLA TORRE , EMANUEL, DAGNA , LORENZO, DOGLIONI , CLAUDIO, Campochiaro, C, Ramirez, Ga, Bozzolo, Ep, Lanzillotta, M, Berti, A, Baldissera, E, Dagna, Lorenzo, Praderio, L, Scotti, R, Tresoldi, M, Roveri, L, Mariani, A, Balzano, G, Castoldi, R, Doglioni, Claudio, Sabbadini, Mg, Della Torre, E., and DELLA TORRE, Emanuel
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Male ,medicine.medical_specialty ,Immunology ,Disease ,Sialadenitis ,Autoimmune Diseases ,Atopy ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Rheumatology ,Recurrence ,Internal medicine ,Orbital Pseudotumor ,parasitic diseases ,medicine ,Immunology and Allergy ,Retroperitoneal space ,Humans ,030212 general & internal medicine ,Retroperitoneal Space ,Glucocorticoids ,Aged ,Retrospective Studies ,030203 arthritis & rheumatology ,integumentary system ,business.industry ,fungi ,Remission Induction ,Retrospective cohort study ,General Medicine ,Cytoreduction Surgical Procedures ,Middle Aged ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Italy ,Pancreatitis ,Immunoglobulin G ,IgG4-related disease ,Female ,business ,Immunosuppressive Agents ,Cohort study - Abstract
Objectives: To describe the clinical features, treatment response, and follow-up of a large cohort of Italian patients with immunoglobulin (Ig)G4-related disease (IgG4-RD) referred to a single tertiary care centre.Method: Clinical, laboratory, histological, and imaging features were retrospectively reviewed. IgG4-RD was classified as definite' or possible' according to international consensus guidelines and comprehensive diagnostic criteria for IgG4-RD. Disease activity was assessed by means of the IgG4-RD Responder Index (IgG4-RD RI).Results: Forty-one patients (15 females, 26 males) were included in this study: 26 with definite' IgG4-RD and 15 with possible' IgG4-RD. The median age at diagnosis was 62years. The median follow-up was 36 months (IQR 24-51). A history of atopy was present in 30% of patients. The pancreas, retroperitoneum, and major salivary glands were the most frequently involved organs. Serum IgG4 levels were elevated in 68% of cases. Thirty-six patients were initially treated with glucocorticoids (GCs) to induce remission. IgG4-RD RI decreased from a median of 7.8 at baseline to 2.9 after 1month of therapy. Relapse occurred in 19/41 patients (46%) and required additional immunosuppressive drugs to maintain long-term remission. Multiple flares occurred in a minority of patients. A single case of orbital pseudotumour did not respond to medical therapy and underwent surgical debulking.Conclusions: IgG4-RD is an elusive inflammatory disease to be considered in the differential diagnosis of isolated or multiple tumefactive lesions. Long-term disease control can be achieved with corticosteroids and immunosuppressive drugs in the majority of cases. ZB 0 ZR 0 ZS 0 Objectives: To describe the clinical features, treatment response, and follow-up of a large cohort of Italian patients with immunoglobulin (Ig)G4-related disease (IgG4-RD) referred to a single tertiary care centre.Method: Clinical, laboratory, histological, and imaging features were retrospectively reviewed. IgG4-RD was classified as definite' or possible' according to international consensus guidelines and comprehensive diagnostic criteria for IgG4-RD. Disease activity was assessed by means of the IgG4-RD Responder Index (IgG4-RD RI).Results: Forty-one patients (15 females, 26 males) were included in this study: 26 with definite' IgG4-RD and 15 with possible' IgG4-RD. The median age at diagnosis was 62years. The median follow-up was 36 months (IQR 24-51). A history of atopy was present in 30% of patients. The pancreas, retroperitoneum, and major salivary glands were the most frequently involved organs. Serum IgG4 levels were elevated in 68% of cases. Thirty-six patients were initially treated with glucocorticoids (GCs) to induce remission. IgG4-RD RI decreased from a median of 7.8 at baseline to 2.9 after 1month of therapy. Relapse occurred in 19/41 patients (46%) and required additional immunosuppressive drugs to maintain long-term remission. Multiple flares occurred in a minority of patients. A single case of orbital pseudotumour did not respond to medical therapy and underwent surgical debulking.Conclusions: IgG4-RD is an elusive inflammatory disease to be considered in the differential diagnosis of isolated or multiple tumefactive lesions. Long-term disease control can be achieved with corticosteroids and immunosuppressive drugs in the majority of cases.
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- 2015
6. Giant cell arteritis restricted to the limb arteries: An overlooked clinical entity
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Berti A, Campochiaro C, Cavalli G, Pepe G, Praderio L, Sabbadini MG, DAGNA , LORENZO, Berti, A, Campochiaro, C, Cavalli, G, Pepe, G, Praderio, L, Sabbadini, Mg, and Dagna, Lorenzo
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- 2015
7. Atypical presentation of Churg-Strauss syndrome or an undescribed hypereosinophilic disease?
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Della Torre E, Tresoldi M, Scotti R, Praderio L, Mellone R, Doglioni C, Sabbadini MG, DELLA TORRE , EMANUEL, PONZONI , MAURILIO, Della Torre, E, Tresoldi, M, Scotti, R, Praderio, L, Mellone, R, Ponzoni, Maurilio, Doglioni, C, Sabbadini, Mg, and DELLA TORRE, Emanuel
- Published
- 2011
8. Rheumatoid arthritis, systemic lupus erythematosus, and STAT4
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DAGNA , LORENZO, Frontino G, Praderio L., Dagna, Lorenzo, Frontino, G, and Praderio, L.
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- 2007
9. THU0543 IGG4-Related Disease in Italy. Clinical Features and Outcomes of a Large Cohort of Patients
- Author
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Campochiaro, C., primary, Ramirez, G., additional, Bozzolo, E., additional, Lanzillotta, M., additional, Berti, A., additional, Baldissera, E., additional, Dagna, L., additional, Praderio, L., additional, Scotti, R., additional, Tresoldi, M., additional, Sabbadini, M.G., additional, and Della Torre, E., additional
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- 2015
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10. IgG4-related disease in Italy: clinical features and outcomes of a large cohort of patients.
- Author
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Campochiaro, C, Ramirez, GA, Bozzolo, EP, Lanzillotta, M, Berti, A, Baldissera, E, Dagna, L, Praderio, L, Scotti, R, Tresoldi, M, Roveri, L, Mariani, A, Balzano, G, Castoldi, R, Doglioni, C, Sabbadini, MG, and Della-Torre, E
- Subjects
IMMUNOGLOBULIN G ,IMMUNOGLOBULIN analysis ,TISSUE wounds ,THERAPEUTIC use of glucocorticoids ,ADRENOCORTICAL hormones ,IMMUNOSUPPRESSIVE agents ,AUTOIMMUNE diseases ,EYE-socket tumors ,IMMUNOGLOBULINS ,LONGITUDINAL method ,PANCREATITIS ,RETROPERITONEUM ,DISEASE relapse ,DISEASE remission ,RETROSPECTIVE studies ,CYTOREDUCTIVE surgery ,SIALADENITIS ,DISEASE complications - Abstract
Objectives: To describe the clinical features, treatment response, and follow-up of a large cohort of Italian patients with immunoglobulin (Ig)G4-related disease (IgG4-RD) referred to a single tertiary care centre. Method: Clinical, laboratory, histological, and imaging features were retrospectively reviewed. IgG4-RD was classified as ‘definite’ or ‘possible’ according to international consensus guidelines and comprehensive diagnostic criteria for IgG4-RD. Disease activity was assessed by means of the IgG4-RD Responder Index (IgG4-RD RI). Results: Forty-one patients (15 females, 26 males) were included in this study: 26 with ‘definite’ IgG4-RD and 15 with ‘possible’ IgG4-RD. The median age at diagnosis was 62 years. The median follow-up was 36 months (IQR 24–51). A history of atopy was present in 30% of patients. The pancreas, retroperitoneum, and major salivary glands were the most frequently involved organs. Serum IgG4 levels were elevated in 68% of cases. Thirty-six patients were initially treated with glucocorticoids (GCs) to induce remission. IgG4-RD RI decreased from a median of 7.8 at baseline to 2.9 after 1 month of therapy. Relapse occurred in 19/41 patients (46%) and required additional immunosuppressive drugs to maintain long-term remission. Multiple flares occurred in a minority of patients. A single case of orbital pseudotumour did not respond to medical therapy and underwent surgical debulking. Conclusions: IgG4-RD is an elusive inflammatory disease to be considered in the differential diagnosis of isolated or multiple tumefactive lesions. Long-term disease control can be achieved with corticosteroids and immunosuppressive drugs in the majority of cases. [ABSTRACT FROM PUBLISHER]
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- 2016
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11. Wegener’s granulomatosis: an analysis of 50 patients
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Di Comite, G., primary, Bonavida, G., additional, Bozzolo, E., additional, Bozzolo, S., additional, Bianchi, S., additional, Ciboddo, G., additional, Tresoldi, M., additional, Praderio, L., additional, and Sabbadini, M.G., additional
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- 2011
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12. Propionibacterium acnes Sepsis in a Previously Healthy Man
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Praderio, L., primary, Dagnaz, L., additional, Beretta, G., additional, Rubin, G., additional, and Ossi, C., additional
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- 1998
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13. Immunohistochemical evidence of a cytokine and chemokine network in three patients with Erdheim-Chester disease: Implications for pathogenesis.
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Stoppacciaro A, Ferrarini M, Salmaggi C, Colarossi C, Praderio L, Tresoldi M, Beretta AA, and Sabbadini MG
- Abstract
OBJECTIVE: Erdheim-Chester disease (ECD) is a rare form of non-Langerhans' cell histiocytosis (LCH) of unknown etiology, characterized by diffuse histiocyte infiltration of bones and soft tissue. The purpose of this study was to assess cell proliferation and expression of cytokines, chemokines, and chemokine receptors that may potentially be important in histiocyte accumulation in ECD lesions. METHODS: Biopsies were performed on 3 patients with ECD. The diagnosis of the disease was based on clinical signs including typical radiologic osteosclerosis, and on the detection of foamy CD68+,CD1a- non-Langerhans' cell histiocytes on histologic examination. The expression of the proliferation marker Ki-67 as well as of selected chemokine/chemokine receptor pairs and cytokines was analyzed by immunohistochemistry. RESULTS: In all samples, Ki-67 was undetectable in CD68+ histiocytes. Conversely, these cells expressed the chemokines CCL2 (monocyte chemotactic protein 1), CCL4/macrophage inflammatory protein 1beta (MIP-1beta), CCL5/RANTES, CCL20/MIP-3alpha, and CCL19/MIP-3beta, and their counter-receptors CCR1, CCR2, CCR3, CCR5, CCR6, and CCR7. Moreover, ECD histiocytes expressed interferon-gamma-inducible 10-kd protein (CXCL10), which is specifically induced by interferon-gamma, and interleukin-6 and RANKL, which are both implicated in bone remodeling. Finally, all cases showed a Th1-type lymphocyte infiltrate. CONCLUSION: Our data indicate that, similar to LCH, ECD lesions are characterized by a complex cytokine and chemokine network, which may orchestrate histiocyte activation and accumulation through an autocrine loop and contribute to the pathogenesis of the disease. [ABSTRACT FROM AUTHOR]
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- 2006
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14. Electrophysiological and MRI evaluation of neurological involvement in Behçet's disease.
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Besana, C, Comi, G, Del Maschio, A, Praderio, L, Vergani, A, Medaglini, S, Martinelli, V, Triulzi, F, and Locatelli, T
- Abstract
Eight patients with stable Behçet's disease were studied by means of multimodality evoked potentials and magnetic resonance imaging to evaluate the possibility of an earlier and objective demonstration of clinical and subclinical Central Nervous System (CNS) involvement. It was shown that both diagnostic techniques are useful for quantitative evaluation of neurological involvement in Behçet's disease; of particular interest was the demonstration of subclinical CNS changes. [ABSTRACT FROM AUTHOR]
- Published
- 1989
15. Peripheral neuropathy in scleroderma
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Corbo, M., Nemni, R., sandro Iannaccone, Quattrini, A., Lodi, M., Praderio, L., Comola, M., Lorenzetti, I., Comi, G., Canal, N., Corbo, M, Nemni, R, Innacone, S, Quattrini, A, Lodi, M, Praderio, L, Comola, M, Lorenzetti, I, Comi, Giancarlo, and Canal, N.
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Adult ,Neurologic Examination ,Scleroderma, Systemic ,Electromyography ,Biopsy ,Muscles ,Peripheral Nervous System Diseases ,Nerve Fibers, Myelinated ,Axons ,Immunoenzyme Techniques ,Muscular Atrophy ,Sural Nerve ,Immunoglobulin G ,Humans ,Female ,Collagen ,Autoantibodies ,Skin - Abstract
Nervous system involvement is rare in progressive systemic sclerosis (PSS). We present a clinical pathological and immunological study of two patients with peripheral sensory motor neuropathy and PSS. In both, the sural nerve biopsies showed axonal degeneration with increased endoneurial connective tissue. There were also clusters of myelinated fibres indicating axonal regeneration. Only mild microangiopathic changes were evident in the endo, peri and epineurial vessels. By Western immunoblots, patients' sera contained a band of reactivity to a protein from peripheral nerve identified as collagen type I. Primary involvement of the peripheral nerves during PSS is very unusual. Abnormal production of collagen tissue and presence of microvascular disease are considered to be two possible causes of neuropathy. We think that our results suggest the important role of the connective tissue proliferation in the pathogenesis of PSS neuropathy.
16. Pseudoxanthoma elasticum and rheumatoid arthritis
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Praderio, L., primary
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- 1987
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17. BERGER'S DISEASE WITH POLYARTERITIS NODOSA
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PRADERIO, L., primary, CORTI, C., additional, SPOSATO, E., additional, TACCAGNI, G. L., additional, VOLPI, A., additional, and SABBADINI, M. G., additional
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- 1989
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18. Budd-Chiari syndrome in a patient with ulcerative colitis: association with anticardiolipin antibodies.
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Praderio, Luisa, Dagna, Lorenzo, Longhi, Paolo, Rubin, Gianpaolo, Sabbadini, Maria Grazia, Praderio, L, Dagna, L, Longhi, P, Rubin, G, and Sabbadini, M G
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- 2000
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19. Rheumatoid arthritis, systemic lupus erythematosus, and STAT4.
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Dagna L, Frontino G, Praderio L, Remmers EF, Plenge RM, and Gregersen PK
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- 2007
20. A relapsing inflammatory syndrome and active human herpesvirus 8 infection.
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Dagna L, Broccolo F, Paties CT, Ferrarini M, Sarmati L, Praderio L, Sabbadini MG, Lusso P, and Malnati MS
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- 2005
21. A Relapsing Inflammatory Syndrome and Active Human Herpesvirus 8 Infection
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Francesco Broccolo, Lorenzo Dagna, Paolo Lusso, Mauro S. Malnati, Maria Grazia Sabbadini, Luisa Praderio, Marina Ferrarini, Carlo Terenzio Paties, Loredana Sarmati, Dagna, Lorenzo, Broccolo, F, Paties, Ct, Ferrarini, M, Sarmati, L, Praderio, L, Sabbadini, Mg, Lusso, P, Malnati, Ms, Dagna, L, Paties, C, Sabbadini, M, and Malnati, M
- Subjects
Pathology ,peripheral blood mononuclear cell ,recurrent disease ,correlation analysis ,viruses ,rash ,lymphatic system disease ,medicine.disease_cause ,Recurrence ,middle aged ,Edema ,Gammaherpesvirinae ,Viral ,Human herpesvirus 8 ,fever ,serodiagnosis ,Herpesviridae Infection ,immunocompetence ,Synovitis ,biology ,Human immunodeficiency virus ,adult ,article ,hyperplasia ,virus diseases ,Sarcoma ,Herpesviridae Infections ,General Medicine ,lymph node ,Viral Load ,Hyperplasia ,Rash ,virology ,Lymphatic disease ,female ,arthritis ,priority journal ,Synoviti ,Herpesvirus 8, Human ,Immunocompetence ,medicine.symptom ,Arthriti ,Human ,virus DNA ,medicine.medical_specialty ,Settore MED/17 - Malattie Infettive ,Kaposi ,Virus ,Herpesviridae ,histology ,blood ,lymphadenopathy ,HIV Seronegativity ,medicine ,case report ,cell proliferation ,clinical feature ,edema ,Herpes virus infection ,human ,Kaposi sarcoma ,splenomegaly ,virus load ,isolation and purification ,pathology ,synovitis ,Arthritis ,DNA, Viral ,Exanthema ,Female ,Humans ,Lymph Nodes ,Lymphatic Diseases ,Middle Aged ,Sarcoma, Kaposi ,Splenomegaly ,Herpesvirus 8 ,business.industry ,DNA ,medicine.disease ,biology.organism_classification ,Immunology ,Lymphatic Disease ,business - Abstract
We describe an immunocompetent 61-year-old woman who was negative for human immunodeficiency virus and who had recurrent human herpesvirus 8 (HHV-8) infection associated with a relapsing systemic inflammatory syndrome characterized by fever, lymphadenopathy, splenomegaly, edema, arthrosynovitis, and rash. Kaposi's sarcoma developed 10 months after the initial clinical presentation. A correlation was documented between the recurrent clinical manifestations and the HHV-8 load in plasma and peripheral-blood mononuclear cells. Histologic examination of an enlarged lymph node heavily infected with HHV-8 revealed an atypical lymphoproliferative disorder characterized by paracortical hyperplasia and collapsed primary and secondary follicles.
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- 2005
22. High blood levels of chromogranin A in giant cell arteritis identify patients refractory to corticosteroid treatment
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Luisa Praderio, Giacomo Dell'Antonio, G. Di Comite, Angelo Corti, Carlo Maria Rossi, Lorenzo Dagna, Maria Grazia Sabbadini, P Previtali, Angelo A. Manfredi, Attilio Maseri, Patrizia Rovere-Querini, Claudio Doglioni, Di Comite, G, Previtali, P, Rossi, Cm, Dell'Antonio, G, ROVERE QUERINI, Patrizia, Praderio, L, Dagna, Lorenzo, Corti, Angelo, Doglioni, Claudio, Maseri, A, Sabbadini, Mg, and Manfredi, ANGELO ANDREA M. A.
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Male ,Pathology ,medicine.medical_specialty ,Giant Cell Arteritis ,Immunology ,General Biochemistry, Genetics and Molecular Biology ,Immune system ,Rheumatology ,Refractory ,Humans ,Immunology and Allergy ,Medicine ,Treatment Failure ,Glucocorticoids ,Neurogenic inflammation ,medicine.diagnostic_test ,biology ,business.industry ,Acute-phase protein ,Chromogranin A ,Prognosis ,medicine.disease ,Peripheral ,Giant cell arteritis ,Erythrocyte sedimentation rate ,biology.protein ,Prednisone ,Female ,business ,Biomarkers ,Follow-Up Studies - Abstract
Giant cell arteritis (GCA) rapidly responds to high-dose corticosteroids. However, smouldering arterial inflammation can persist despite the absence of symptoms and altered acute phase reactants. In patients that are refractory, symptoms relapse during steroid tapering and vascular complications may develop. The erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) level are not sensitive enough markers to detect refractory disease.1 The neuroendocrine system regulates innate and acquired immune responses, influencing cytokine synthesis and limiting tissue damage via release of neurotransmitters and peptides in peripheral tissues. Chromogranin A in particular is a candidate marker linking neurogenic inflammation and vascular inflammation.2 We investigated by ELISA, as described previously,3 the …
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- 2009
23. PTX3 in small-vessel vasculitides: an independent indicator of disease activity produced at sites of inflammation
- Author
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Angelo A. Manfredi, Giacomo Dell'Antonio, Fausto Fazzini, Andrea Doni, Enrica Bozzolo, Luisa Praderio, Elena Dal Cin, Francesca D'Auria, Giuseppe Peri, Gianfranco Ciboddo, Alberto Mantovani, Maria Grazia Sabbadini, Patrizia Rovere Querini, Fazzini, F, Peri, G, Doni, A, Dell'Antonio, G, Dal Cin, E, Bozzolo, E, D'Auria, F, Praderio, L, Ciboddo, G, Sabbadini, Mg, Manfredi, ANGELO ANDREA M. A., Mantovani, A, and ROVERE QUERINI, Patrizia
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CREST Syndrome ,Adult ,Male ,Systemic disease ,Pathology ,medicine.medical_specialty ,Immunology ,Churg-Strauss Syndrome ,Arthritis, Rheumatoid ,Rheumatology ,Immunology and Allergy ,Medicine ,Humans ,Lupus Erythematosus, Systemic ,Pharmacology (medical) ,Acute-Phase Reaction ,Child ,Aged ,medicine.diagnostic_test ,business.industry ,Granulomatosis with Polyangiitis ,Sclerodactyly ,PTX3 ,Middle Aged ,medicine.disease ,Serum Amyloid P-Component ,C-Reactive Protein ,Rheumatoid arthritis ,Skin biopsy ,Acute Disease ,Female ,Endothelium, Vascular ,medicine.symptom ,business ,Vasculitis ,Microscopic polyangiitis ,Biomarkers - Abstract
Objective To verify whether the prototypical long pentraxin PTX3 represents an indicator of the activity of small-vessel vasculitis. Methods Concentrations of PTX3, a pentraxin induced in endothelium by cytokines, were measured by enzyme-linked immunosorbent assay in the sera of 43 patients with Churg-Strauss syndrome, Wegener's granulomatosis, and microscopic polyangiitis. PTX3 was also measured in the sera of 28 patients with systemic lupus erythematosus (SLE), 22 with rheumatoid arthritis, and 16 with CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, telangiectasias). Serum concentrations of C-reactive protein (CRP) were measured by immunoturbidimetry. The cells involved in PTX3 production in vivo were identified in skin biopsy samples. Results Patients with active vasculitis had significantly higher concentrations of PTX3 than did those with quiescent disease (P < 0.001). PTX3 levels in the latter group were similar to those in healthy controls. PTX3 levels were higher in patients with untreated vasculitis and lower in patients who underwent immunosuppressive treatments (P < 0.005). In contrast, patients with active SLE had negligible levels of the pentraxin. PTX3 levels did not correlate with CRP levels in vasculitis patients. Endothelial cells produced PTX3 in active skin lesions. Conclusion PTX3 represents a novel acute-phase reactant produced at sites of active vasculitis.
- Published
- 2002
24. Charcot’s Arthropathy of the Hip
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Luisa Praderio, Giulio Cavalli, Cavalli, G., and Praderio, L.
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Male ,musculoskeletal diseases ,congenital, hereditary, and neonatal diseases and abnormalities ,medicine.medical_specialty ,Immunology ,Lesion ,Rheumatology ,Weight loss ,Charcot's arthropathy ,Arthropathy ,Deformity ,medicine ,Humans ,Immunology and Allergy ,Depression (differential diagnoses) ,Aged ,business.industry ,Osteomyelitis ,medicine.disease ,nervous system diseases ,Surgery ,Radiography ,body regions ,Hip Joint ,Arthropathy, Neurogenic ,medicine.symptom ,Paraplegia ,business - Abstract
Charcot’s arthropathy is a degenerative condition of the joints secondary to a neurologic lesion, resulting in deformity and increased bone reabsorption1. Misdiagnosis as osteomyelitis or neoplasm is frequent. A 67-year-old man with a 19-year history of posttraumatic sensorimotor paraplegia, depression, and alcoholism was evaluated for weight loss of 4 kg over 2 months. At examination, he was depressed, malnourished, and emaciated. Sensorimotor paraplegia …
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- 2013
25. Propionibacterium acnes sepsis in a previously healthy man
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C. Ossi, Giacomo Beretta, Lorenzo Dagna, Luisa Praderio, Gianpaolo Rubin, Praderio, L, Dagna, Lorenzo, Beretta, G, Rubin, G, and Ossi, C.
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Microbiology (medical) ,Adult ,Male ,Pathology ,medicine.medical_specialty ,Propionibacterium ,Sepsis syndrome ,Bacteremia ,Sepsis ,Propionibacterium acnes ,Bone Marrow ,medicine ,Humans ,Gram-Positive Bacterial Infections ,Propionibacteriaceae ,biology ,business.industry ,medicine.disease ,biology.organism_classification ,Dermatology ,Culture Media ,medicine.anatomical_structure ,Infectious Diseases ,Blood ,Immunology ,Bone marrow ,business - Published
- 1998
26. Hypoglycaemia and Lactic Acidosis in a MALT Non Hodgkin's Lymphoma
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Lorenzo Dagna, Luisa Praderio, Lucilla D. Monti, P. M. Piatti, Francesca Tantardini, Gabriele Di Comite, Di Comite, G, Dagna, Lorenzo, Piatti, Pm, Monti, Ld, Tantardini, F, and Praderio, L.
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Cancer Research ,Pathology ,medicine.medical_specialty ,Fatal Outcome ,Stomach Neoplasms ,immune system diseases ,hemic and lymphatic diseases ,medicine ,Humans ,B cell ,Acidosis ,business.industry ,Lymphoma, B-Cell, Marginal Zone ,Hematology ,Acute Kidney Injury ,Middle Aged ,medicine.disease ,Hypoglycemia ,Lymphoma ,Non-Hodgkin's lymphoma ,medicine.anatomical_structure ,Oncology ,Lactic acidosis ,Shock (circulatory) ,Acidosis, Lactic ,Female ,medicine.symptom ,Tumor Lysis Syndrome ,Complication ,business ,Mucosa-associated lymphoid tissue - Abstract
Hypoglycaemia associated with lactic acidosis is a rare complication of lymphomas; only four cases have been previously reported. Recent studies provide evidence of direct consumption of glucose by the tumour cells, leading to lactic acidosis. We report the case of a 64-year-old patient with a gastric diffuse large B cell non-Hodgkin's lymphoma transformed from an indolent mucosa associated lymphoid tissue (MALT) lymphoma, admitted to our department for acute renal failure due to a tumour lysis syndrome. After recovery from renal failure, she developed severe hypoglycaemia and lactic acidosis refractory to therapy. She died after the onset of shock and coma.
- Published
- 2002
27. Budd-Chiari Syndrome in a Patient With Ulcerative Colitis
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Luisa Praderio, Lorenzo Dagna, Paolo Longhi, Gianpaolo Rubin, Maria Grazia Sabbadini, Praderio, L, Dagna, Lorenzo, Longhi, P, Rubin, G, and Sabbadini, Mg
- Subjects
Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Budd-Chiari Syndrome ,Liver transplantation ,Gastroenterology ,Internal medicine ,Immunopathology ,medicine ,Humans ,biology ,Vascular disease ,business.industry ,medicine.disease ,Ulcerative colitis ,Thrombosis ,Antibodies, Anticardiolipin ,Immunology ,biology.protein ,Budd–Chiari syndrome ,Colitis, Ulcerative ,Anti-cardiolipin antibodies ,Antibody ,business - Abstract
This is the first reported case of a young patient with ulcerative colitis who developed acute Budd-Chiari syndrome and was found positive for anticardiolipin antibodies. Although an association between ulcerative colitis and Budd-Chiari syndrome, and between the latter and antiphospholipid antibodies, has been shown in the literature, the coexistence of these three conditions has never been reported. The patient we describe did poorly and was considered as a candidate for liver transplantation in spite of prompt heparin therapy, probably because of the presence of multiple risk factors.
- Published
- 2000
28. Electrophysiological and MRI evaluation of neurological involvement in Behcet's disease
- Author
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C Besana, Stefania Medaglini, Fabio Triulzi, A. Del Maschio, T. Locatelli, Andrea Vergani, G. Comi, L Praderio, Vittorio Martinelli, Besana, C, Comi, G, DEL MASCHIO, Alessandro, Praderio, L, Vergani, A, Medaglini, S, Martinelli, V, Triulzi, F, and Locatelli, T.
- Subjects
Pathology ,medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Eye disease ,Central nervous system ,Magnetic resonance imaging ,Behcet's disease ,Disease ,Electroencephalography ,medicine.disease ,stomatognathic diseases ,Psychiatry and Mental health ,Electrophysiology ,medicine.anatomical_structure ,Medicine ,Surgery ,Neurology (clinical) ,business ,Research Article ,Subclinical infection - Abstract
Eight patients with stable Behçet's disease were studied by means of multimodality evoked potentials and magnetic resonance imaging to evaluate the possibility of an earlier and objective demonstration of clinical and subclinical Central Nervous System (CNS) involvement. It was shown that both diagnostic techniques are useful for quantitative evaluation of neurological involvement in Behçet's disease; of particular interest was the demonstration of subclinical CNS changes.
- Published
- 1989
29. Sustainability in Internal Medicine: A Year-Long Ward-Wide Observational Study.
- Author
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Ramirez GA, Damanti S, Caruso PF, Mette F, Pagliula G, Cariddi A, Sartorelli S, Falbo E, Scotti R, Di Terlizzi G, Dagna L, Praderio L, Sabbadini MG, Bozzolo EP, and Tresoldi M
- Abstract
Population aging and multimorbidity challenge health system sustainability, but the role of assistance-related variables rather than individual pathophysiological factors in determining patient outcomes is unclear. To identify assistance-related determinants of sustainable hospital healthcare, all patients hospitalised in an Internal Medicine Unit (n = 1073) were enrolled in a prospective year-long observational study and split 2:1 into a training (n = 726) and a validation subset (n = 347). Demographics, comorbidities, provenance setting, estimates of complexity (cumulative illness rating scale, CIRS: total, comorbidity, CIRS-CI, and severity, CIRS-SI subscores) and intensity of care (nine equivalents of manpower score, NEMS) were analysed at individual and Unit levels along with variations in healthcare personnel as determinants of in-hospital mortality, length of stay and nosocomial infections. Advanced age, higher CIRS-SI, end-stage cancer, and the absence of immune-mediated diseases were correlated with higher mortality. Admission from nursing homes or intensive care units, dependency on activity of daily living, community- or hospital-acquired infections, oxygen support and the number of exits from the Unit along with patient/physician ratios were associated with prolonged hospitalisations. Upper gastrointestinal tract disorders, advanced age and higher CIRS-SI were associated with nosocomial infections. In addition to demographic variables and multimorbidity, physician number and assistance context affect hospitalisation outcomes and healthcare sustainability.
- Published
- 2024
- Full Text
- View/download PDF
30. Bortezomib in type I cryoglobulinemic vasculitis: are we acting too late?
- Author
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Ramirez GA, Campochiaro C, Salmaggi C, Pagliula G, D'Aliberti T, Marcatti M, Tresoldi M, and Praderio L
- Subjects
- Amputation, Surgical, Cryoglobulinemia complications, Cryoglobulinemia diagnosis, Early Diagnosis, Foot Diseases drug therapy, Foot Diseases etiology, Humans, Male, Middle Aged, Monoclonal Gammopathy of Undetermined Significance, Necrosis etiology, Paraproteinemias complications, Severity of Illness Index, Toes blood supply, Toes pathology, Treatment Outcome, Vasculitis complications, Vasculitis etiology, Antineoplastic Agents administration & dosage, Bortezomib administration & dosage, Cryoglobulinemia drug therapy, Foot Diseases surgery, Necrosis surgery, Toes surgery, Vasculitis drug therapy
- Abstract
Type II and type III cryoglobulinemic vasculitis (CV) are characterized by a deranged immune function due to concomitant chronic infections or rheumatic disorders. Conversely, type I CV is caused by plasma cell dyscrasia. Bortezomib is a proteasome inhibitor that is largely employed as a first-line treatment for multiple myeloma. The use of bortezomib in cases of monoclonal gammopathy of undetermined significance (MGUS)-related refractory type I CV has been reported in only four patients. In the current report, we discuss the efficacy of bortezomib treatment in a patient with type I CV, with a focus on the suitability and early application of this drug.
- Published
- 2015
- Full Text
- View/download PDF
31. Charcot's arthropathy of the hip.
- Author
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Cavalli G and Praderio L
- Subjects
- Aged, Humans, Male, Radiography, Arthropathy, Neurogenic diagnostic imaging, Hip Joint diagnostic imaging
- Published
- 2013
- Full Text
- View/download PDF
32. Atypical presentation of Churg-Strauss syndrome or an undescribed hypereosinophilic disease?
- Author
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Della-Torre E, Tresoldi M, Scotti R, Praderio L, Mellone R, Ponzoni M, Doglioni C, and Sabbadini MG
- Subjects
- Aged, Humans, Male, Churg-Strauss Syndrome diagnosis, Churg-Strauss Syndrome pathology, Churg-Strauss Syndrome therapy, Hypereosinophilic Syndrome diagnosis, Hypereosinophilic Syndrome pathology, Hypereosinophilic Syndrome therapy
- Published
- 2011
- Full Text
- View/download PDF
33. Meningeal involvement in Wegener's granulomatosis is associated with localized disease.
- Author
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Di Comite G, Bozzolo EP, Praderio L, Tresoldi M, and Sabbadini MG
- Subjects
- Adult, Antibodies, Antineutrophil Cytoplasmic analysis, Cranial Nerve Diseases etiology, Cranial Nerve Diseases pathology, Female, Headache etiology, Headache pathology, Humans, Male, Meninges chemistry, Meninges diagnostic imaging, Meningitis diagnosis, Meningitis pathology, Middle Aged, Radiography, Seizures etiology, Seizures pathology, Granulomatosis with Polyangiitis complications, Meninges pathology, Meningitis etiology
- Abstract
Meningeal involvement is a rare occurrence in Wegener's Granulomatosis (WG). A Medline search uncovered only 48 previously reported cases. Here we describe the clinical features of meningeal involvement in WG and to evaluate the association with systemic disease extension. Through a systematic literature review of papers concerning meningeal involvement in WG, we collected and analysed data about sex, age, disease extension, symptoms, cerebrospinal fluid examination, imaging, ANCA and histology about previously reported patients. Headache is almost always the first symptom of meningeal involvement in WG. Later in the course of the disease other abnormalities may develop. Among them cranial nerve palsy, seizures and encephalopathy are the most frequent. Diagnosis is obtained by neuroimaging, which may disclose two distinct patterns of meningeal thickening: diffuse or focal. 62.9% of patients tests positive for ANCA. Histology typically shows necrotizing granulomatosis. Meningeal involvement is by far more frequent in the setting of localized WG. Meningitis is a rare complication of WG. It usually develops in patients with localized disease who are more likely to have destructive lesions of the upper airways. It may be recognized by a constellation of clinical and radiological findings and by histological signs of necrotizing granulomatosis, with little or no vasculitis.
- Published
- 2006
34. [Wegener's granulomatosis: an analysis of 50 patients].
- Author
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Di Comite G, Bonavida G, Bozzolo E, Bianchi S, Ciboddo G, Tresoldi M, Praderio L, and Sabbadini MG
- Subjects
- Adolescent, Adult, Aged, Child, Female, Granulomatosis with Polyangiitis drug therapy, Humans, Male, Middle Aged, Granulomatosis with Polyangiitis complications
- Abstract
Objectives: To evaluate the rate of different organs involvement in 50 patients with Wegener's Granulomatosis (GW), and to describe their clinical manifestations and their response to treatment., Methods: We evaluated 50 consecutive patients with GW, come to our attention from January 1987 to May 2003. 43 patients met the 1990 American College of Rheumatology (ACR) criteria for classification of GW; 7 patients the 1993 ELK criteria., Results: 82% of patients presented Ear/Nose/Throat (ENT) involvement, which is the most common site of inflammation. 22% of our patients had ENT-restricted disease; in 78% of cases disease extended to other organs. Lungs were involved in 72% of cases; kidney in 36%; eye in 24%; nervous system (NS) in 14% (central NS in 10% and peripheral NS in 4%); skin in 10%; heart in 8%; testis in 4%. Arthritis was present in 10% of patients. We discuss treatment of all patients and response to therapy of those 28 whose follow-up is available., Conclusions: Involvement of airways and kidney is by far the most common in GW, though potentially any other organ or system may be affected. The total rate of other organs involvement is 70%.
- Published
- 2005
- Full Text
- View/download PDF
35. Polymyalgia rheumatica and giant-cell arteritis.
- Author
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Praderio L, Di Comite G, and Saporiti N
- Subjects
- Bone Density, Female, Humans, Male, Osteoporosis chemically induced, Diphosphonates therapeutic use, Giant Cell Arteritis drug therapy, Glucocorticoids adverse effects, Osteoporosis prevention & control, Polymyalgia Rheumatica drug therapy
- Published
- 2002
36. Hypoglycaemia and lactic acidosis in a MALT non Hodgkin's lymphoma.
- Author
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Di Comite G, Dagna L, Piatti PM, Monti LD, Tantardini F, and Praderio L
- Subjects
- Acute Kidney Injury etiology, Fatal Outcome, Female, Humans, Lymphoma, B-Cell, Marginal Zone metabolism, Middle Aged, Stomach Neoplasms metabolism, Tumor Lysis Syndrome complications, Acidosis, Lactic etiology, Hypoglycemia etiology, Lymphoma, B-Cell, Marginal Zone complications, Stomach Neoplasms complications
- Abstract
Hypoglycaemia associated with lactic acidosis is a rare complication of lymphomas; only four cases have been previously reported. Recent studies provide evidence of direct consumption of glucose by the tumour cells, leading to lactic acidosis. We report the case of a 64-year-old patient with a gastric diffuse large B cell non-Hodgkin's lymphoma transformed from an indolent mucosa associated lymphoid tissue (MALT) lymphoma, admitted to our department for acute renal failure due to a tumour lysis syndrome. After recovery from renal failure, she developed severe hypoglycaemia and lactic acidosis refractory to therapy. She died after the onset of shock and coma.
- Published
- 2002
- Full Text
- View/download PDF
37. PTX3 in small-vessel vasculitides: an independent indicator of disease activity produced at sites of inflammation.
- Author
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Fazzini F, Peri G, Doni A, Dell'Antonio G, Dal Cin E, Bozzolo E, D'Auria F, Praderio L, Ciboddo G, Sabbadini MG, Manfredi AA, Mantovani A, and Querini PR
- Subjects
- Acute Disease, Acute-Phase Reaction, Adult, Aged, Arthritis, Rheumatoid blood, Arthritis, Rheumatoid diagnosis, Arthritis, Rheumatoid immunology, Biomarkers, C-Reactive Protein metabolism, CREST Syndrome blood, CREST Syndrome diagnosis, CREST Syndrome immunology, Child, Churg-Strauss Syndrome diagnosis, Churg-Strauss Syndrome immunology, Endothelium, Vascular chemistry, Endothelium, Vascular immunology, Endothelium, Vascular metabolism, Female, Granulomatosis with Polyangiitis diagnosis, Granulomatosis with Polyangiitis immunology, Humans, Lupus Erythematosus, Systemic blood, Lupus Erythematosus, Systemic diagnosis, Lupus Erythematosus, Systemic immunology, Male, Middle Aged, Serum Amyloid P-Component metabolism, C-Reactive Protein analysis, Churg-Strauss Syndrome blood, Granulomatosis with Polyangiitis blood, Serum Amyloid P-Component analysis
- Abstract
Objective: To verify whether the prototypical long pentraxin PTX3 represents an indicator of the activity of small-vessel vasculitis., Methods: Concentrations of PTX3, a pentraxin induced in endothelium by cytokines, were measured by enzyme-linked immunosorbent assay in the sera of 43 patients with Churg-Strauss syndrome, Wegener's granulomatosis, and microscopic polyangiitis. PTX3 was also measured in the sera of 28 patients with systemic lupus erythematosus (SLE), 22 with rheumatoid arthritis, and 16 with CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, telangiectasias). Serum concentrations of C-reactive protein (CRP) were measured by immunoturbidimetry. The cells involved in PTX3 production in vivo were identified in skin biopsy samples., Results: Patients with active vasculitis had significantly higher concentrations of PTX3 than did those with quiescent disease (P < 0.001). PTX3 levels in the latter group were similar to those in healthy controls. PTX3 levels were higher in patients with untreated vasculitis and lower in patients who underwent immunosuppressive treatments (P < 0.005). In contrast, patients with active SLE had negligible levels of the pentraxin. PTX3 levels did not correlate with CRP levels in vasculitis patients. Endothelial cells produced PTX3 in active skin lesions., Conclusion: PTX3 represents a novel acute-phase reactant produced at sites of active vasculitis.
- Published
- 2001
- Full Text
- View/download PDF
38. Acute echinococcosis: a case report.
- Author
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Di Comite G, Dognini G, Gaiera G, Ieri R, and Praderio L
- Subjects
- Acute Disease, Aged, Humans, Male, Echinococcosis, Pulmonary diagnosis
- Abstract
We report the case of a 69-year-old man with acute pulmonary echinococcosis. A computed tomographic scan of the thorax revealed the presence of multiple nodules in both lungs, and laboratory tests showed eosinophilia and the presence of antibodies against Echinococcus granulosus. Therapy with albendazole led to resolution of the pulmonary nodules and a normalization of the white cell count. To our knowledge this is the first described case of acute echinococcosis, as the diagnosis of this disease is usually delayed to chronic phases. Therefore, finding unexplained eosinophilia, especially in association with pulmonary nodules, should lead one to suspect acute hydatid disease.
- Published
- 2000
- Full Text
- View/download PDF
39. Peripheral neuropathy in scleroderma.
- Author
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Corbo M, Nemni R, Iannaccone S, Quattrini A, Lodi M, Praderio L, Comola M, Lorenzetti I, Comi G, and Canal N
- Subjects
- Adult, Autoantibodies analysis, Axons pathology, Biopsy, Collagen immunology, Electromyography, Female, Humans, Immunoenzyme Techniques, Immunoglobulin G analysis, Muscles innervation, Muscles pathology, Muscular Atrophy diagnosis, Muscular Atrophy pathology, Muscular Atrophy physiopathology, Nerve Fibers, Myelinated pathology, Neurologic Examination, Peripheral Nervous System Diseases diagnosis, Peripheral Nervous System Diseases pathology, Scleroderma, Systemic diagnosis, Scleroderma, Systemic pathology, Skin innervation, Skin pathology, Sural Nerve pathology, Peripheral Nervous System Diseases physiopathology, Scleroderma, Systemic physiopathology
- Abstract
Nervous system involvement is rare in progressive systemic sclerosis (PSS). We present a clinical pathological and immunological study of two patients with peripheral sensory motor neuropathy and PSS. In both, the sural nerve biopsies showed axonal degeneration with increased endoneurial connective tissue. There were also clusters of myelinated fibres indicating axonal regeneration. Only mild microangiopathic changes were evident in the endo, peri and epineurial vessels. By Western immunoblots, patients' sera contained a band of reactivity to a protein from peripheral nerve identified as collagen type I. Primary involvement of the peripheral nerves during PSS is very unusual. Abnormal production of collagen tissue and presence of microvascular disease are considered to be two possible causes of neuropathy. We think that our results suggest the important role of the connective tissue proliferation in the pathogenesis of PSS neuropathy.
- Published
- 1993
40. Association of lupus anticoagulant with polyarteritis nodosa: report of a case.
- Author
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Praderio L, D'Angelo A, Taccagni G, Peccatori S, Silvestris M, D'Angelo SV, and Rugarli C
- Subjects
- Amputation, Surgical, Blood Coagulation Factors analysis, Cyclophosphamide therapeutic use, Female, Humans, Iloprost therapeutic use, Lupus Coagulation Inhibitor, Middle Aged, Necrosis, Polyarteritis Nodosa drug therapy, Polyarteritis Nodosa pathology, Prednisone therapeutic use, Toes pathology, Toes surgery, Autoantibodies analysis, Blood Coagulation Factors immunology, Polyarteritis Nodosa immunology
- Abstract
A patient with a documented diagnosis of polyarteritis nodosa and laboratory evidence of a circulating lupus anticoagulant is described. Additional clinical features suggestive of the antiphospholipid antibody syndrome were found. The patient underwent amputation of the first two digits of the foot due to ischemic necrosis. Steroid and immunosuppressive treatment resulted in clinical improvement and disappearance of the circulating anticoagulant, without necessitating additional treatment with oral anticoagulants. The presence of the lupus anticoagulant might have worsened the vascular damage done by polyarteritis nodosa in this patient.
- Published
- 1990
41. Essential mixed cryoglobulinemia: a report on 14 cases.
- Author
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Silvestris M, Praderio L, Peccatori S, Marcatti M, Storti M, Ciboddo G, and Rugarli C
- Subjects
- Adult, Aged, Arthritis etiology, Female, Humans, Kidney Diseases etiology, Liver Diseases etiology, Male, Middle Aged, Peripheral Nervous System Diseases etiology, Skin Diseases etiology, Vasculitis etiology, Cryoglobulinemia blood, Cryoglobulinemia complications, Cryoglobulinemia pathology
- Abstract
Fourteen cases of Essential Mixed Cryoglobulinemia (EMC) are described in this report. Clinical and laboratory manifestations in our patients were similar to those previously reported in literature, although involvement of the peripheral nervous system was much more prevalent in our series. We suggest that peripheral neuropathy should be systematically searched in EMC patients.
- Published
- 1989
42. Berger's disease with polyarteritis nodosa.
- Author
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Praderio L, Corti C, Sposato E, Taccagni GL, Volpi A, and Sabbadini MG
- Subjects
- Adolescent, Biopsy, Blood Vessels pathology, Glomerulonephritis, IGA pathology, Humans, Kidney pathology, Male, Polyarteritis Nodosa drug therapy, Polyarteritis Nodosa pathology, Prednisolone therapeutic use, Skin blood supply, Skin pathology, Glomerulonephritis, IGA complications, Polyarteritis Nodosa complications
- Abstract
We describe a patient with Berger's disease and polyarteritis nodosa. This association has not been described previously in the literature. A causal relationship between the two diseases is suggested.
- Published
- 1989
- Full Text
- View/download PDF
43. Guillain-Barré syndrome in Castleman's lymphopathy.
- Author
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Ciboddo G, Praderio L, Spagnol G, Sironi M, Comi G, Medaglini S, Canal N, and Rugarli C
- Subjects
- Castleman Disease immunology, Humans, Lymphocytes immunology, Male, Middle Aged, Polyradiculoneuropathy immunology, Castleman Disease complications, Polyradiculoneuropathy complications
- Published
- 1987
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