Préel, Marie, Rackauskaite, Gija, Larsen, Mads Langager, Laursen, Bjarne, Lorentzen, Jakob, Born, Alfred Peter, Langhoff-Roos, Jens, Uldall, Peter, Høi-Hansen, Christina Engel, Préel, Marie, Rackauskaite, Gija, Larsen, Mads Langager, Laursen, Bjarne, Lorentzen, Jakob, Born, Alfred Peter, Langhoff-Roos, Jens, Uldall, Peter, and Høi-Hansen, Christina Engel
AIM: We aimed at describing clinical findings in children with dyskinetic as compared to bilateral spastic cerebral palsy (CP).METHODS: Data was extracted from the Danish nationwide CP register. Participants were born in 1999-2007 and were 5-6 years at ascertainment.RESULTS: The total number of CP cases was 1,165 of which 92 had dyskinetic and 540 bilateral spastic CP. Prevalence of dyskinetic CP was 0.16 per 1000 live-births. In participants with dyskinetic compared to bilateral spastic CP, there was more frequently an Apgar level less than five at five minutes (22.7% versus 11.2%) and neonatal seizures (43.5% versus 28.5%), but less respiratory deficiency, hyperbilirubinaemia, and sepsis. Impairment based on gross motor function classification was more severe in dyskinetic CP (level III-V 90.0% versus 66.0%). In dyskinetic CP there was a high rate of reduced developmental quotient (68.1%), visual impairment (39.3%), and epilepsy (51.6%). Basal ganglia lesions were more prevalent in dyskinetic compared to bilateral spastic CP (27.7% vs. 12.8%).CONCLUSION: Cases of dyskinetic CP had overlapping clinical features with cases of bilateral spastic CP, but differed significantly in several perinatal risk factors. The children with dyskinetic CP had experienced more peri- or neonatal adverse events, and neurodevelopmental impairment was severe. This article is protected by copyright. All rights reserved.