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1. Incorporating Quantitative Single Photon Emission Computed Tomography into Radiation Therapy Treatment Planning for Lung Cancer: Impact of Attenuation and Scatter Correction on the Single Photon Emission Computed Tomography–Weighted Mean Dose and Functional Lung Segmentation

Author

Yin, Lingshu, Shcherbinin, Sergey, Celler, Anna, Thompson, Anna, Fua, Tsien-Fei, Liu, Mitchell, Duzenli, Cheryl, Gill, Brad, Sheehan, Finbar, Powe, John, Worsley, Daniel, Marks, Lawrence, and Moiseenko, Vitali

Published
2010
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4. Can a Day 4 Bone Scan Accurately Determine the Presence or Absence of Scaphoid Fracture?

Author

Murphy, David G., Eisenhauer, Mary A., Powe, John, and Pavlofsky, William

Subjects
Health
Abstract

Byline: David G Murphy, Mary A Eisenhauer, John Powe, William Pavlofsky Abstract: Study objective: To evaluate the accuracy of day 4 bone scans in predicting the presence or absence of fracture in patients with 'clinical scaphoid fracture.' Design: Prospective sensitivity study of ED patients with clinical scaphoid fractures. Each patient was immobilized in a thumb spica cast and had day 4 bone scans of both wrists and hands. Blinded day 4 bone scan results were ultimately compared with the diagnosis on day 14 when patients returned for repeat clinical examination and radiographs. In cases of equivocal radiographic or clinical examination results, a day 14 bone scan was performed. Setting: Two tertiary care teaching hospital emergency departments. Participants: All ED patients older than 16 years with the diagnosis of clinical scaphoid fracture were eligible. Results: Ninety-nine patients were enrolled and successfully completed the study protocol from October 1990 through November 1992. One patient had bilateral injury, for a total of 100 completed studies. Day 4 bone scans were 100% sensitive and 92% specific, for a positive predictive value of 65%, a negative predictive value of 100%, and accuracy of 93% (95% confidence interval, 88% to 98%). Many other types of fractures were identified on the day 4 scans, including those of the triquetra, distal radius, capitate, hamate, trapezoid, trapezium, and metacarpals. Conclusion: Day 4 bone scans are an accurate means of ruling out scaphoid fracture. However, because of a significant number of false-positive scans at day 4, they do not reliably confirm the diagnosis of scaphoid fracture. The bone scans also permitted identification of several other wrist fractures that had not been radiographically apparent. [Murphy DG, Eisenhauer MA, Powe J, Pavlofsky W: Can a day 4 bone scan accurately determine the presence or absence of scaphoid fracture? Ann Emerg Med October 1995;26:434-438.] Article History: Received 22 November 1994; Revised 21 March 1995; Accepted 10 April 1995 Article Note: (footnote) [star] From the Department of Medicine* and Diagnostic Radiology and Nuclear Medicinea , University of Western Ontario, London, Ontario, Canada., [star][star] Supported by the Emergency Medicine Associates Research Fund and the Lawson Research Fund., a Address for reprints: David G Murphy, MD, FRCPC, DABEM, Department of Emergency Medicine, St Joseph's Health Centre, 268 Grosvenor Street, London, Ontario, Canada N6A 4V2, 519-646-6100, ext 4233, Fax 519-646-6038, aa Reprint no. 47/1/66975

Published
1995

6. Pulmonary thallium-201 uptake following dipyridamole-exercise combination compared with single modality stress testing

Author

Hurwitz, Gilbert A., O'Donoghue, J. Paul, Powe, John E., Gravelle, Denis R., MacDonald, A. Craig, and Finnie, Keith J.C.

Subjects
Thallium, Dipyridamole, Coronary heart disease -- Prognosis, Exercise tests, Radioisotope scanning -- Methods, Health
Abstract

Angiographic and clinical determinants of pulmonary uptake of thallium-201 were assessed in a laboratory setting where supine bicycle exercise is used for stress testing in the absence of limiting pharmacologic or physical factors, and where symptom-limited exercise is added to intravenous dipyridamole infusion in other cases. Angiographic correlation was available in 400 patients, including 130 tested with exercise, 94 in whom only handgrip or abbreviated bicycle exercise could be used after dipyridamole, and 176 in whom intravenous dipyridamole was combined with a significant level of exercise. For each test model, lung/myocardial ratios on the immediate image were highly correlated (p [is less than or equal to] 0.001) with a score based on the number of critical coronary artery stenoses, with grading by contrast ventriculography, and with the number of stenosed ([is less than or equal to] 50%) arteries; relationships (p < 0.05) to history of myocardial infarction and to gender were also present. Multiple regression analysis showed the critical stenosis score and ventricular dysfunction to be the only significant determinants. When dipyridamole based tests were compared with exercise, curves of receiver-operating characteristics showed a tendency to better diagnostic performance. When dipyridamole is incorporated in stress testing, the value of increased lung uptake as an ancillary diagnostic sign is similar to that established for exercise.

Published
1992

26. Inborn Error of Vitamin B12 Metabolism

Author

Al Essa, Mohammed, primary, Sakati, Nadia A., additional, Dabbagh, Omar, additional, Joshi, Surrendra, additional, Al Jishi, Emtethal A., additional, Rashed, Mohamed S., additional, Powe, John E., additional, and Ozand, Pinar T., additional

Published
1998
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50. Brief.

Author

Sheth, Raj D., Jaynes, Margaret E., Al Essa, Mohammed, Sakati, Nadia A., Dabbagh, Omar, Joshi, Surrendra, Al Jishi, Emtethal A., Rashed, Mohamed S., Powe, John E., Ozand, Pinar T., Ismail, Essam A.R., Al-Shammari, Nufood, Anim, Jehoram T., Moosa, Allie, Sokol, Deborah K., Dahlmann, Allen, and Dunn, David W.

Published
1998

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