603 results on '"Pouton, Colin W."'
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2. mRNA vaccines encoding membrane-anchored RBDs of SARS-CoV-2 mutants induce strong humoral responses and can overcome immune imprinting
3. CRISPR-Cas13b-mediated suppression of HBV replication and protein expression
4. Conversion of vaccines from low to high immunogenicity by antibodies with epitope complementarity
5. Interim results from a phase I randomized, placebo-controlled trial of novel SARS-CoV-2 beta variant receptor-binding domain recombinant protein and mRNA vaccines as a 4th dose booster
6. Broad immunity to SARS-CoV-2 variants of concern mediated by a SARS-CoV-2 receptor-binding domain protein vaccine
7. Resolving subcellular pH with a quantitative fluorescent lifetime biosensor
8. From influenza to COVID-19: Lipid nanoparticle mRNA vaccines at the frontiers of infectious diseases
9. Molecular Dynamics Simulations and Experimental Results Provide Insight into Clinical Performance Differences between Sandimmune® and Neoral® Lipid-Based Formulations
10. Aqueous phase behavior of the PEO-containing non-ionic surfactant C12E6: A molecular dynamics simulation study
11. Interaction with biliary and pancreatic fluids drives supersaturation and drug absorption from lipid-based formulations of low (saquinavir) and high (fenofibrate) permeability poorly soluble drugs
12. Assessing the cellular toxicity of peptide inhibitors of intracellular protein-protein interactions by microinjection
13. Lipophilic Salts and Lipid-Based Formulations: Enhancing the Oral Delivery of Octreotide
14. Beyond the Endosomal Bottleneck: Understanding the Efficiency of mRNA/LNP Delivery.
15. The impact of size and charge on the pulmonary pharmacokinetics and immunological response of the lungs to PLGA nanoparticles after intratracheal administration to rats
16. Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson’s Disease
17. Unravelling cytosolic delivery of cell penetrating peptides with a quantitative endosomal escape assay
18. Transcriptional signature in microglia associated with Aβ plaque phagocytosis
19. Local inflammation alters the lung disposition of a drug loaded pegylated liposome after pulmonary dosing to rats
20. SIRPA, VCAM1 and CD34 identify discrete lineages during early human cardiovascular development
21. A Nonionic Polyethylene Oxide (PEO) Surfactant Model: Experimental and Molecular Dynamics Studies of Kolliphor EL
22. Improvement in the Predicted Partitioning of Alcohol and Polyethylene Oxide Groups Between Water and Octanol (logP) in Molecular Dynamics Simulations
23. Location of Solvated Probe Molecules Within Nonionic Surfactant Micelles Using Molecular Dynamics
24. Self-Crosslinking Lipopeptide/DNA/PEGylated Particles: A New Platform for DNA Vaccination Designed for Assembly in Aqueous Solution
25. A comparison of the lung clearance kinetics of solid lipid nanoparticles and liposomes by following the 3H-labelled structural lipids after pulmonary delivery in rats
26. Transformation of Biopharmaceutical Classification System Class I and III Drugs Into Ionic Liquids and Lipophilic Salts for Enhanced Developability Using Lipid Formulations
27. mRNA vaccines encoding membrane-anchored receptor-binding domains of SARS-CoV-2 mutants induce strong humoral responses and can overcome immune imprinting
28. A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem Cells
29. Delivery and Expression of mRNA in the Secondary Lymphoid Organs Drive Immune Responses to Lipid Nanoparticle-mRNA Vaccines after Intramuscular Injection
30. Disposition and safety of inhaled biodegradable nanomedicines: Opportunities and challenges
31. 50 years of oral lipid-based formulations: Provenance, progress and future perspectives
32. Tissue-specific Calibration of Real-time PCR Facilitates Absolute Quantification of Plasmid DNA in Biodistribution Studies
33. Molecular Dynamics Simulation Studies of Bile, Bile Salts, Lipid-Based Drug Formulations, and mRNA–Lipid Nanoparticles: A Review
34. Stem Cell Technology
35. Targeting Melanocortin Receptors Using SNAr-Type Macrocyclization: A Doubly Orthogonal Route to Cyclic Peptide Conjugates
36. TGFβ3, dibutyryl cAMP and a notch inhibitor modulate phenotype late in stem cell-derived dopaminergic neuron maturation
37. The mRNA Vaccine Technology Era and the Future Control of Parasitic Infections
38. ‘Stealth’ lipid-based formulations: Poly(ethylene glycol)-mediated digestion inhibition improves oral bioavailability of a model poorly water soluble drug
39. Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 4: Proposing a New Lipid Formulation Performance Classification System
40. Choice of Nonionic Surfactant Used to Formulate Type IIIA Self-Emulsifying Drug Delivery Systems and the Physicochemical Properties of the Drug Have a Pronounced Influence on the Degree of Drug Supersaturation that Develops During In Vitro Digestion
41. Acute or Delayed Systemic Administration of Human Amnion Epithelial Cells Improves Outcomes in Experimental Stroke
42. A new in vitro lipid digestion – in vivo absorption model to evaluate the mechanisms of drug absorption from lipid-based formulations
43. In vitro assessment of drug-free and fenofibrate-containing lipid formulations using dispersion and digestion testing gives detailed insights into the likely fate of formulations in the intestine
44. Strategies to Address Low Drug Solubility in Discovery and Development
45. Efficiently Specified Ventral Midbrain Dopamine Neurons from Human Pluripotent Stem Cells Under Xeno‐Free Conditions Restore Motor Deficits in Parkinsonian Rodents
46. High Molecular Weight DNA Enrichment with Peptide Nucleic Acid Probes
47. Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase
48. Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 1: Method Parameterization and Comparison of In Vitro Digestion Profiles Across a Range of Representative Formulations
49. Broad immunity to SARS-CoV-2 variants of concern mediated by a SARS-CoV-2 receptor-binding domain protein vaccine
50. Mechanism of Microtubule-facilitated “Fast Track” Nuclear Import
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