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209 results on '"Poulsen, Gry"'

7. Vitamin D regulates microbiome-dependent cancer immunity

Author

Giampazolias, Evangelos, primary, Pereira da Costa, Mariana, additional, Lam, Khiem C., additional, Lim, Kok Haw Jonathan, additional, Cardoso, Ana, additional, Piot, Cécile, additional, Chakravarty, Probir, additional, Blasche, Sonja, additional, Patel, Swara, additional, Biram, Adi, additional, Castro-Dopico, Tomas, additional, Buck, Michael D., additional, Rodrigues, Richard R., additional, Poulsen, Gry Juul, additional, Palma-Duran, Susana A., additional, Rogers, Neil C., additional, Koufaki, Maria A., additional, Minutti, Carlos M., additional, Wang, Pengbo, additional, Vdovin, Alexander, additional, Frederico, Bruno, additional, Childs, Eleanor, additional, Lee, Sonia, additional, Simpson, Ben, additional, Iseppon, Andrea, additional, Omenetti, Sara, additional, Kelly, Gavin, additional, Goldstone, Robert, additional, Nye, Emma, additional, Suárez-Bonnet, Alejandro, additional, Priestnall, Simon L., additional, MacRae, James I., additional, Zelenay, Santiago, additional, Patil, Kiran Raosaheb, additional, Litchfield, Kevin, additional, Lee, James C., additional, Jess, Tine, additional, Goldszmid, Romina S., additional, and Reis e Sousa, Caetano, additional

Published
2024
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15. Educational Attainment and Pregnancy Outcomes: A Danish Register-Based Study of the Influence of Childhood Social Disadvantage on Later Socioeconomic Disparities in Induced Abortion, Spontaneous Abortion, Stillbirth and Preterm Delivery

Author

Hegelund, Emilie Rune, Poulsen, Gry Juul, and Mortensen, Laust Hvas

Subjects
Health care disparities -- Analysis, Pregnancy, Complications of -- Risk factors, Pregnant women -- Health aspects -- Social aspects, Pediatric research, Health care industry
Abstract

Objectives Socioeconomic disparities in pregnancy outcomes have been found across times and places, but there is a lack of studies investigating the underlying causes. The present study investigated the influence of child protective services in the pregnant woman's family of origin as a proxy of childhood social disadvantage. Methods The study population comprised all registered pregnancies in Denmark during the period from 2000 to 2009 that resulted in an induced abortion, spontaneous abortion, stillbirth or live birth (N = 786,054). Linear regression was used to analyze the associations between educational attainment and pregnancy outcomes in models with and without adjustment for age, parental educational attainment and child protective services in the family of origin. Further, it was tested whether child protective services in the pregnant woman's family of origin modified the associations between educational attainment and pregnancy outcomes. Results Women with low educational attainment had a higher risk of induced abortion, stillbirth and preterm delivery and a lower risk of spontaneous abortion. These associations were to some extent explained by child protective services in the family of origin. Further, child protective services in the pregnant woman's family of origin modified the association between educational attainment and risk of preterm delivery. Thus, women with high educational attainment were not found to differ in risk of preterm delivery according to child protective services in the family of origin Conclusions for Practice Information on childhood social disadvantage may enrich our understanding of the socioeconomic disparities in pregnancy outcomes, Author(s): Emilie Rune Hegelund [sup.1] , Gry Juul Poulsen [sup.1] , Laust Hvas Mortensen [sup.1] Author Affiliations: (Aff1) 0000 0001 0674 042X, grid.5254.6, Department of Public Health, University of Copenhagen, [...]

Published
2019
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16. Association of light-to-moderate alcohol drinking in pregnancy with preterm birth and birth weight: elucidating bias by pooling data from nine European cohorts

Author

Strandberg-Larsen, Katrine, Poulsen, Gry, Bech, Bodil Hammer, Chatzi, Leda, Cordier, Sylvaine, Dale, Maria Teresa Grønning, Fernandez, Marieta, Henriksen, Tine Brink, Jaddoe, Vincent WV, Kogevinas, Manolis, Kruithof, Claudia J., Lindhard, Morten Søndergaard, Magnus, Per, Nohr, Ellen Aagaard, Richiardi, Lorenzo, Rodriguez-Bernal, Clara L., Rouget, Florence, Rusconi, Franca, Vrijheid, Martine, and Andersen, Anne-Marie Nybo

Published
2017

18. Early ileocecal resection for Crohn's disease is associated with improved long-term outcomes compared to anti-tumor necrosis factor therapy:a population-based cohort study

Author

Agrawal, Manasi, Ebert, Anthony C., Poulsen, Gry, Ungaro, Ryan C., Faye, Adam S., Jess, Tine, Colombel, Jean-Frederic, and Allin, Kristine H.

Abstract

Background and aimsEarly Crohn’s disease (CD) treatment involves anti-tumor necrosis factor (TNF) agents, while ileocecal resection (ICR) is reserved for complicated CD or treatment failure. We aimed to compare long-term outcomes of primary ICR and anti-TNF therapy for ileocecal CD.MethodsUsing cross-linked nationwide registers, we identified all individuals diagnosed with ileal or ileocecal CD between 2003 and 2018, treated with ICR or anti-TNF agents within one year of diagnosis. The primary outcome was a composite of one or more of the following: CD-related hospitalization, systemic corticosteroid exposure, CD-related surgery, and perianal CD. We conducted adjusted Cox proportional hazards regression analyses and determined cumulative risk of different treatments following primary ICR or anti-TNF therapy.ResultsOf 16,443 individuals diagnosed with CD, 1,279 individuals fulfilled the inclusion criteria. Of these, 45.4% and 54.6% of individuals underwent ICR and received anti-TNF, respectively. The composite outcome occurred in 273 individuals (IR 110/1000 person years (PY)) in the ICR group and in 318 individuals (IR 202/1000 PY) in the anti-TNF group. The risk of the composite outcome was 33% lower with ICR, compared to anti-TNF (aHR 0.67; 95% CI 0.54, 0.83). ICR was associated with reduced risk of systemic corticosteroid exposure and CD-related surgery, but not other secondary outcomes. The proportion of individuals on IMM, anti-TNF, who underwent subsequent resection, or on no therapy 5 years post-ICR was 46.3%, 16.8%, 1.8%, and 49.7%, respectively.ConclusionThese data suggest that ICR may have a role as first-line therapy in CD management and challenge the current paradigm of reserving surgery for complicated CD refractory or intolerant to medications. Yet, given inherent biases associated with observational data, our findings should be interpreted and applied cautiously in clinical decision-making.

Published
2023

27. Endocrine disease history and the risk of postpartum depression.

Author

Rasmussen, Marie-Louise H., Poulsen, Gry J., Videbech, Poul, Wohlfahrt, Jan, and Melbye, Mads

Subjects
ENDOCRINE diseases, POSTPARTUM depression, PREGNANCY complications, POLYCYSTIC ovary syndrome, GESTATIONAL diabetes, THYROID diseases
Abstract

Background: Previous research has suggested that some women are at increased risk of postpartum depression (PPD) because of an extra sensitivity to fluctuating hormones before and after parturition. This may particularly apply to women with endocrine disease, characterised by a less than optimal capability to self-regulate the hormonal feedback system. Aims: To investigate if women with endocrine disease history are at increased risk of developing PPD. Method: Based on information from Danish national registers, this nationwide cohort study included 888 989 deliveries (1995–2018). Endocrine disease history was defined as thyroid disease, pre-pregnancy diabetes, polycystic ovary syndrome and/or previous gestational diabetes within 10 years before pregnancy start. PPD was defined as use of antidepressants and/or hospital contact for depression within 6 months after childbirth. Results: Among 888 989 deliveries, 4.1% had a history of endocrine disease and 0.5% had a PPD episode. Overall, women with an endocrine disease history had a 42% (risk ratio 1.42, 95% CI 1.24–1.62) higher risk of PPD when compared with women with no endocrine disease. However, we also found the reverse association, whereby women with a PPD history had a 50% (hazard ratio 1.5, 95% CI 1.4–1.6) higher risk of endocrine disease when compared with women with no PPD history. Conclusions: Women with endocrine disease history had a 40% higher risk of PPD compared with women with no endocrine disease. More attention should be given to pregnant women with endocrine disease history to increase awareness of early signs of PPD. The bi-directionality of the association points to a common underlying factor. [ABSTRACT FROM AUTHOR]

Published
2023
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33. Exploring Educational Disparities in Risk of Preterm Delivery: A Comparative Study of 12 European Birth Cohorts

Author

Poulsen, Gry, Strandberg-Larsen, Katrine, Mortensen, Laust, Barros, Henrique, Cordier, Sylvaine, Correia, Sofia, Danileviciute, Asta, van Eijsden, Manon, Fernández-Somoano, Ana, Gehring, Ulrike, Grazuleviciene, Regina, Hafkamp-de Groen, Esther, Henriksen, Tine Brink, Sndergaard Jensen, Morten, Larrañaga, Isabel, Magnus, Per, Pickett, Kate, Raat, Hein, Richiardi, Lorenzo, Rouget, Florence, Rusconi, Franca, Stoltenberg, Camilla, Uphoff, Eleonora P., Vrijkotte, Tanja G. M., Wijga, Alet H., Vrijheid, Martine, Osler, Merete, and Nybo Andersen, Anne-Marie

Published
2015
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37. Pregnancy and Birth Cohort Resources in Europe: a Large Opportunity for Aetiological Child Health Research

Author

Larsen, Pernille Stemann, Kamper-Jrgensen, Mads, Adamson, Ashley, Barros, Henrique, Bonde, Jens Peter, Brescianini, Sonia, Brophy, Sinead, Casas, Maribel, Devereux, Graham, Eggesb, Merete, Fantini, Maria Pia, Frey, Urs, Gehring, Ulrike, Grazuleviciene, Regina, Henriksen, Tine Brink, Hertz-Picciotto, Irva, Heude, Barbara, Hryhorczuk, Daniel O., Inskip, Hazel, Jaddoe, Vincent W.V., Lawlor, Debbie A, Ludvigsson, Johnny, Kelleher, Cecily, Kiess, Wieland, Koletzko, Berthold, Kuehni, Claudia Elisabeth, Kull, Inger, Kyhl, Henriette Boye, Magnus, Per, Momas, Isabelle, Murray, Dierdre, Pekkanen, Juha, Polanska, Kinga, Porta, Daniela, Poulsen, Gry, Richiardi, Lorenzo, Roeleveld, Nel, Skovgaard, Anne Mette, Sram, Radim J., Strandberg-Larsen, Katrine, Thijs, Carel, Van Eijsden, Manon, Wright, John, Vrijheid, Martine, and Andersen, Anne-Marie Nybo

Published
2013
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49. Social Cognition, Language, and Social Behavior in 7-Year-Old Children at Familial High-Risk of Developing Schizophrenia or Bipolar Disorder: The Danish High Risk and Resilience Study VIA 7—A Population-Based Cohort Study

Author

Christiani, Camilla Jerlang, primary, Jepsen, Jens R M, additional, Thorup, Anne, additional, Hemager, Nicoline, additional, Ellersgaard, Ditte, additional, Spang, Katrine S, additional, Burton, Birgitte K, additional, Gregersen, Maja, additional, Søndergaard, Anne, additional, Greve, Aja N, additional, Gantriis, Ditte L, additional, Poulsen, Gry, additional, Uddin, Md Jamal, additional, Seidman, Larry J, additional, Mors, Ole, additional, Plessen, Kerstin J, additional, and Nordentoft, Merete, additional

Published
2019
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