15 results on '"Potts, James F."'
Search Results
2. Dietary patterns derived from principal component analysis (PCA) and risk of colorectal cancer: a systematic review and meta-analysis
- Author
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Garcia-Larsen, Vanessa, Morton, Victoria, Norat, Teresa, Moreira, André, Potts, James F., Reeves, Tim, and Bakolis, Ioannis
- Published
- 2019
- Full Text
- View/download PDF
3. Indoor risk factors for cough and their relation to wheeze and sensitization in Chilean young adults
- Author
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Potts, James F., Rona, Roberto J., Oyarzun, Manuel J., Amigo, Hugo, and Bustos, Patricia
- Subjects
Wheeze -- Risk factors ,Smoking -- Risk factors ,Public health ,Teenagers ,Youth ,Allergens ,Government ,Health care industry - Abstract
Objectives. We assessed the effects of indoor risk factors, including smoking, on different types of cough and on cough and wheeze in combination. Methods. Our sample was composed of 1232 men and women residing in a semi-rural area of Chile. We used a standardized questionnaire, sensitization to 8 allergens, and bronchial hyperresponsiveness to methacholine to assess cough and wheeze characteristics. Information was gathered on dampness, mold, ventilation, heating, housing quality, smoking, and environmental tobacco smoke exposure. Results. Most exposures were associated with cough alone or cough in combination with wheeze. Smoking, past smoking, and environmental tobacco smoke exposure were strongly associated with dry cough and wheeze. The use of coal for heating was associated with dry cough. Leaks, mold, and lack of kitchen ventilation were associated with cough and wheeze. Nocturnal cough and productive cough were associated with specific types of sensitization, but dry cough was not. Productive cough was associated with hyperresponsiveness to methacholine. Conclusions. Several different types of indoor exposures, including environmental tobacco smoke exposure, are important contributors to morbidity associated with cough and wheeze. A vigorous preventive strategy designed to lower exposures to indoor risk factors would lower rates of respiratory morbidity. (Am J Public Health. 2008;98:680-686. doi: 10.2105/AJPH.2006.093302)
- Published
- 2008
4. Randomised, double blind, placebo-controlled trial of selenium supplementation in adult asthma
- Author
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Shaheen, Seif O, Newson, Roger B, Rayman, Margaret P, Wong, Angela P-L, Tumilty, Michael K, Phillips, Joanna M, Potts, James F, Kelly, Frank J, White, Patrick T, and Burney, Peter G J
- Published
- 2007
5. Dietary intake of flavonoids and ventilatory function in European adults : a GA²LEN study
- Author
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Garcia-Larsen, Vanessa, Thawer, Narjis, Charles, David, Cassidy, Aedin, van Zele, Thibaut, Thilsing, Trine, Ahlström, Matti, Haahtela, Tari, Keil, Thomas, Matricardi, Paolo M., Brożek, Grzegorz, Kowalski, Marek L., Makowska, Joanna, Niżankowska-Mogilnicka, Ewa, Rymarczyk, Barbara, Loureiro, Carlos, Todo Bom, Ana, Bachert, Claus, Forsberg, Bertil, Janson, Christer, Torén, Kjell, Potts, James F., and Burney, Peter G. J.
- Subjects
Näringslära ,Nutrition and Dietetics ,flavonoids ,lung function ,pro-anthocyanidins ,GA2LEN - Abstract
BACKGROUND: Flavonoids exert anti-inflammatory properties and modulate oxidative stress in vitro, suggesting a protective effect on lung function, but epidemiological studies examining this association are scarce. METHODS: A stratified random sample was drawn from the GA²LEN screening survey, in which 55,000 adults aged 15 to 75 answered a questionnaire on respiratory symptoms. Post-bronchodilator spirometry was obtained from 2850 subjects. Forced vital capacity (FVC), the ratio between the forced exhaled volume in 1 second (FEV₁) and FVC (FEV₁/FVC), FVC below lower limit of normal (FVC < LLN), and FEV₁/FVC < LLN were calculated. Intake of the six main subclasses of flavonoids was estimated using the GA²LEN Food Frequency Questionnaire. Adjusted associations between outcomes and each subclass of flavonoids were examined with multivariate regressions. Simes' procedure was used to test for multiple comparisons. RESULTS: A total of 2599 subjects had valid lung function and dietary data. A lower prevalence of FVC < LLN (airway restriction) was observed in those with higher total flavonoid (adjusted odds ratio (aOR), higher vs. lowest quintile intake 0.58; 95% Confidence Interval (CI) 0.36, 0.94), and pro-anthocyanidin intakes (aOR 0.47; 95% CI 0.27, 0.81). A higher FEV₁/FVC was associated with higher intakes of total flavonoids and pro-anthocyanidins (adjusted correlation coefficient (a β-coeff 0.33; 0.10, 0.57 and a β-coeff 0.44; 95% CI 0.19, 0.69, respectively). After Simes' procedure, the statistical significance of each of these associations was attenuated but remained below 0.05, with the exception of total flavonoids and airway restriction. CONCLUSIONS: This population-based study in European adults provides cross-sectional evidence of a positive association of total flavonoid intake and pro-anthocyanidins and ventilatory function, and a negative association with spirometric restriction in European adults.
- Published
- 2018
6. Age at menopause and lung function: a Mendelian randomisation study
- Author
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van der Plaat, Diana A., primary, Pereira, Miguel, additional, Pesce, Giancarlo, additional, Potts, James F., additional, Amaral, André F.S., additional, Dharmage, Shyamali C., additional, Garcia-Aymerich, Judith M., additional, Thompson, John R., additional, Gómez Real, Francisco, additional, Jarvis, Deborah L., additional, Minelli, Cosetta, additional, and Leynaert, Bénédicte, additional
- Published
- 2019
- Full Text
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7. Is fruit and vegetable intake associated with asthma or chronic rhino-sinusitis in European adults? Results from the Global Allergy and Asthma Network of Excellence (GA(2)LEN) Survey
- Author
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Garcia-Larsen, Vanessa, Arthur, Rhonda, Potts, James F., Howarth, Peter H., Ahlström, Matti, Haahtela, Tari, Loureiro, Carlos, Bom, Ana Todo, Brożek, Grzegorz, Makowska, Joanna, Kowalski, Marek L., Thilsing, Trine, Keil, Thomas, Matricardi, Paolo M., Torén, Kjell, van Zele, Thibaut, Bachert, Claus, Rymarczyk, Barbara, Janson, Christer, Forsberg, Bertil, Niżankowska-Mogilnicka, Ewa, Burney, Peter G. J., Department of Dermatology, Allergology and Venereology, Clinicum, HUS Inflammation Center, and Commission of the European Communities
- Subjects
RISK ,Science & Technology ,Allergy ,Respiratory Medicine and Allergy ,DIETARY ANTIOXIDANTS ,GALEN ,FLAVONOIDS ,Occupational Health and Environmental Health ,GA2LEN ,Asthma ,Fruits ,Europe ,Arbetsmedicin och miljömedicin ,Meta-analysis ,Chronic rhino-sinusitis ,DISEASES ,3121 General medicine, internal medicine and other clinical medicine ,Vegetables ,GA(2)LEN ,PATTERNS ,Adults ,ddc:610 ,Life Sciences & Biomedicine ,Lungmedicin och allergi - Abstract
Background: Fruits and vegetables are rich in compounds with proposed antioxidant, anti-allergic and anti-inflammatory properties, which could contribute to reduce the prevalence of asthma and allergic diseases. Objective: We investigated the association between asthma, and chronic rhino-sinusitis (CRS) with intake of fruits and vegetables in European adults. Methods: A stratified random sample was drawn from the Global Allergy and Asthma Network of Excellence (GA2LEN) screening survey, in which 55,000 adults aged 15-75 answered a questionnaire on respiratory symptoms. Asthma score (derived from self-reported asthma symptoms) and CRS were the outcomes of interest. Dietary intake of 22 subgroups of fruits and vegetables was ascertained using the internationally validated GA2LEN Food Frequency Questionnaire. Adjusted associations were examined with negative binomial and multiple regressions. Simes procedure was used to control for multiple testing. Results: A total of 3206 individuals had valid data on asthma and dietary exposures of interest. 22.8% reported having at least 1 asthma symptom (asthma score ≥1), whilst 19.5% had CRS. After adjustment for potential confounders, asthma score was negatively associated with intake of dried fruits (β-coefficient -2.34; 95% confidence interval [CI] -4.09, -0.59), whilst CRS was statistically negatively associated with total intake of fruits (OR 0.73; 95% CI 0.55, 0.97). Conversely, a positive association was observed between asthma score and alliums vegetables (adjusted β-coefficient 0.23; 95% CI 0.06, 0.40). None of these associations remained statistically significant after controlling for multiple testing. Conclusion and clinical relevance: There was no consistent evidence for an association of asthma or CRS with fruit and vegetable intake in this representative sample of European adults.
- Published
- 2017
8. Is fruit and vegetable intake associated with asthma or chronic rhino- sinusitis in European adults?
- Author
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Garcia-Larsen, Vanessa, Arthur, Rhonda, Potts, James F., Howarth, Peter H., Ahlstrom, Matti, Haahtela, Tari, Loureiro, Carlos, Keil, Thomas, and Matricardi, Paolo M.
- Subjects
Europe ,Meta-analysis ,Chronic rhino-sinusitis ,Vegetables ,Adults ,600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit ,GA2LEN ,Asthma ,Fruits - Abstract
Background Fruits and vegetables are rich in compounds with proposed antioxidant, anti-allergic and anti-inflammatory properties, which could contribute to reduce the prevalence of asthma and allergic diseases. Objective We investigated the association between asthma, and chronic rhino-sinusitis (CRS) with intake of fruits and vegetables in European adults. Methods A stratified random sample was drawn from the Global Allergy and Asthma Network of Excellence (GA2LEN) screening survey, in which 55,000 adults aged 15–75 answered a questionnaire on respiratory symptoms. Asthma score (derived from self-reported asthma symptoms) and CRS were the outcomes of interest. Dietary intake of 22 subgroups of fruits and vegetables was ascertained using the internationally validated GA2LEN Food Frequency Questionnaire. Adjusted associations were examined with negative binomial and multiple regressions. Simes procedure was used to control for multiple testing. Results A total of 3206 individuals had valid data on asthma and dietary exposures of interest. 22.8% reported having at least 1 asthma symptom (asthma score ≥1), whilst 19.5% had CRS. After adjustment for potential confounders, asthma score was negatively associated with intake of dried fruits (β-coefficient −2.34; 95% confidence interval [CI] −4.09, −0.59), whilst CRS was statistically negatively associated with total intake of fruits (OR 0.73; 95% CI 0.55, 0.97). Conversely, a positive association was observed between asthma score and alliums vegetables (adjusted β-coefficient 0.23; 95% CI 0.06, 0.40). None of these associations remained statistically significant after controlling for multiple testing. Conclusion and clinical relevance There was no consistent evidence for an association of asthma or CRS with fruit and vegetable intake in this representative sample of European adults.
- Published
- 2017
9. Dietary patterns derived from principal component analysis (PCA) and risk of colorectal cancer: a systematic review and meta-analysis
- Author
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Garcia-Larsen, Vanessa, primary, Morton, Victoria, additional, Norat, Teresa, additional, Moreira, André, additional, Potts, James F., additional, Reeves, Tim, additional, and Bakolis, Ioannis, additional
- Published
- 2018
- Full Text
- View/download PDF
10. Dietary antioxidants and 10-year lung function decline in adults from the ECRHS survey
- Author
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Garcia-Larsen, Vanessa, primary, Potts, James F., additional, Omenaas, Ernst, additional, Heinrich, Joachim, additional, Svanes, Cecilie, additional, Garcia-Aymerich, Judith, additional, Burney, Peter G., additional, and Jarvis, Deborah L., additional
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- 2017
- Full Text
- View/download PDF
11. Is fruit and vegetable intake associated with asthma or chronic rhino-sinusitis in European adults? Results from the Global Allergy and Asthma Network of Excellence (GA2LEN) Survey
- Author
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Garcia-Larsen, Vanessa, primary, Arthur, Rhonda, additional, Potts, James F., additional, Howarth, Peter H., additional, Ahlström, Matti, additional, Haahtela, Tari, additional, Loureiro, Carlos, additional, Bom, Ana Todo, additional, Brożek, Grzegorz, additional, Makowska, Joanna, additional, Kowalski, Marek L., additional, Thilsing, Trine, additional, Keil, Thomas, additional, Matricardi, Paolo M., additional, Torén, Kjell, additional, van Zele, Thibaut, additional, Bachert, Claus, additional, Rymarczyk, Barbara, additional, Janson, Christer, additional, Forsberg, Bertil, additional, Niżankowska-Mogilnicka, Ewa, additional, and Burney, Peter G. J., additional
- Published
- 2017
- Full Text
- View/download PDF
12. Changes in symptoms of asthma and rhinitis by sensitization status over ten years in a cohort of young Chilean adults
- Author
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Garcia-Larsen, Vanessa, primary, Potts, James F., additional, Del Giacco, Stefano, additional, Bustos, Patricia, additional, Diaz, Patricia V., additional, Amigo, Hugo, additional, Oyarzun, Manuel, additional, and Rona, Roberto J., additional
- Published
- 2016
- Full Text
- View/download PDF
13. Dietary antioxidants and 10-year lung function decline in adults from the ECRHS survey
- Author
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Garcia-Larsen, Vanessa, Potts, James F., Omenaas, Ernst R., Heinrich, Joachim, Svanes, Cecilie, García Aymerich, Judith, Burney, Peter, and Jarvis, Deborah
- Subjects
Adult ,Lung Diseases ,Male ,Smoking ,Vital Capacity ,food and beverages ,Pulmons -- Malalties ,Original Articles ,Middle Aged ,Health Surveys ,Antioxidants ,respiratory tract diseases ,Diet ,Europe ,Lung Function ,Forced Expiratory Volume ,Multivariate Analysis ,Linear Models ,Humans ,Dieta ,Female ,Longitudinal Studies ,Lung - Abstract
The relationship between lung function decline and dietary antioxidants over 10 years in adults from three European countries was investigated. In 2002, adults from three participating countries of the European Community Respiratory Health Survey (ECRHS) answered a questionnaire and underwent spirometry (forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC)), which were repeated 10 years later. Dietary intake was estimated at baseline with food frequency questionnaires (FFQ). Associations between annual lung function decline (mL) and diet (tertiles) were examined with multivariable analyses. Simes’ procedure was applied to control for multiple testing. A total of 680 individuals (baseline mean age 43.8±6.6 years) were included. A per-tertile increase in apple and banana intake was associated with a 3.59 mL·year−1 (95% CI 0.40, 7.68) and 3.69 mL·year−1 (95% CI 0.25, 7.14) slower decline in FEV1 and FVC, respectively. Tomato intake was also associated with a slower decline in FVC (4.5 mL·year−1; 95% CI 1.28, 8.02). Only the association with tomato intake remained statistically significant after the Simes’ procedure was performed. Subgroup analyses showed that apple, banana and tomato intake were all associated with a slower decline in FVC in ex-smokers. Intake of fruits and tomatoes might delay lung function decline in adults, particularly in ex-smokers., A higher intake of fruits and tomato is associated with a slower lung function decline, particularly in ex-smokers http://ow.ly/5LLv30gK9Bn
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14. Dietary Intake of Flavonoids and Ventilatory Function in European Adults: A GA²LEN Study.
- Author
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Garcia-Larsen V, Thawer N, Charles D, Cassidy A, van Zele T, Thilsing T, Ahlström M, Haahtela T, Keil T, Matricardi PM, Brożek G, Kowalski ML, Makowska J, Niżankowska-Mogilnicka E, Rymarczyk B, Loureiro C, Todo Bom A, Bachert C, Forsberg B, Janson C, Torén K, Potts JF, and Burney PG
- Subjects
- Adolescent, Adult, Aged, Anthocyanins administration & dosage, Anthropometry, Cross-Sectional Studies, Female, Follow-Up Studies, Humans, Lung metabolism, Male, Middle Aged, Nutrition Assessment, Oxidative Stress drug effects, Prevalence, Spirometry, Surveys and Questionnaires, Vital Capacity, Young Adult, Diet, Flavonoids administration & dosage, Pulmonary Ventilation, White People
- Abstract
Background: Flavonoids exert anti-inflammatory properties and modulate oxidative stress in vitro, suggesting a protective effect on lung function, but epidemiological studies examining this association are scarce., Methods: A stratified random sample was drawn from the GA²LEN screening survey, in which 55,000 adults aged 15 to 75 answered a questionnaire on respiratory symptoms. Post-bronchodilator spirometry was obtained from 2850 subjects. Forced vital capacity (FVC), the ratio between the forced exhaled volume in 1 second (FEV₁) and FVC (FEV₁/FVC), FVC below lower limit of normal (FVC < LLN), and FEV₁/FVC < LLN were calculated. Intake of the six main subclasses of flavonoids was estimated using the GA²LEN Food Frequency Questionnaire. Adjusted associations between outcomes and each subclass of flavonoids were examined with multivariate regressions. Simes' procedure was used to test for multiple comparisons., Results: A total of 2599 subjects had valid lung function and dietary data. A lower prevalence of FVC < LLN (airway restriction) was observed in those with higher total flavonoid (adjusted odds ratio (aOR), higher vs. lowest quintile intake 0.58; 95% Confidence Interval (CI) 0.36, 0.94), and pro-anthocyanidin intakes (aOR 0.47; 95% CI 0.27, 0.81). A higher FEV₁/FVC was associated with higher intakes of total flavonoids and pro-anthocyanidins (adjusted correlation coefficient (a β-coeff 0.33; 0.10, 0.57 and a β-coeff 0.44; 95% CI 0.19, 0.69, respectively). After Simes' procedure, the statistical significance of each of these associations was attenuated but remained below 0.05, with the exception of total flavonoids and airway restriction., Conclusions: This population-based study in European adults provides cross-sectional evidence of a positive association of total flavonoid intake and pro-anthocyanidins and ventilatory function, and a negative association with spirometric restriction in European adults., Competing Interests: The authors declare no conflict of interest.
- Published
- 2018
- Full Text
- View/download PDF
15. Is fruit and vegetable intake associated with asthma or chronic rhino-sinusitis in European adults? Results from the Global Allergy and Asthma Network of Excellence (GA 2 LEN) Survey.
- Author
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Garcia-Larsen V, Arthur R, Potts JF, Howarth PH, Ahlström M, Haahtela T, Loureiro C, Bom AT, Brożek G, Makowska J, Kowalski ML, Thilsing T, Keil T, Matricardi PM, Torén K, van Zele T, Bachert C, Rymarczyk B, Janson C, Forsberg B, Niżankowska-Mogilnicka E, and Burney PGJ
- Abstract
Background: Fruits and vegetables are rich in compounds with proposed antioxidant, anti-allergic and anti-inflammatory properties, which could contribute to reduce the prevalence of asthma and allergic diseases., Objective: We investigated the association between asthma, and chronic rhino-sinusitis (CRS) with intake of fruits and vegetables in European adults., Methods: A stratified random sample was drawn from the Global Allergy and Asthma Network of Excellence (GA
2 LEN) screening survey, in which 55,000 adults aged 15-75 answered a questionnaire on respiratory symptoms. Asthma score (derived from self-reported asthma symptoms) and CRS were the outcomes of interest. Dietary intake of 22 subgroups of fruits and vegetables was ascertained using the internationally validated GA2 LEN Food Frequency Questionnaire. Adjusted associations were examined with negative binomial and multiple regressions. Simes procedure was used to control for multiple testing., Results: A total of 3206 individuals had valid data on asthma and dietary exposures of interest. 22.8% reported having at least 1 asthma symptom (asthma score ≥1), whilst 19.5% had CRS. After adjustment for potential confounders, asthma score was negatively associated with intake of dried fruits (β-coefficient -2.34; 95% confidence interval [CI] -4.09, -0.59), whilst CRS was statistically negatively associated with total intake of fruits (OR 0.73; 95% CI 0.55, 0.97). Conversely, a positive association was observed between asthma score and alliums vegetables (adjusted β-coefficient 0.23; 95% CI 0.06, 0.40). None of these associations remained statistically significant after controlling for multiple testing., Conclusion and Clinical Relevance: There was no consistent evidence for an association of asthma or CRS with fruit and vegetable intake in this representative sample of European adults.- Published
- 2017
- Full Text
- View/download PDF
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