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Cet article propose de s’intéresser à un vieux projet, qui ne constitue pas nécessairement une controverse « vive » mais qui fut remis au centre des débats par le SCoT Fier-Aravis en 2019. Il s’agit de la liaison entre les domaines skiables de La Clusaz et du Grand Bornand par le Danay, dans le massif des Aravis. Ce secteur actuellement non équipé permettrait d’afficher un vaste domaine relié, en mesure de concurrencer en partie d’autres dans les Alpes du Nord. Mais ce projet, outre les interrogations sur l’intermittence des discussions le concernant et sa faisabilité, suscite des contestations environnementales dans un massif considéré comme peu équipé jusqu’alors. Dès lors, il s’avère intéressant pour questionner la notion de potentiel conflictuel — dont cet article se propose de jeter les bases — et les risques de survenue d’un conflit environnemental si la liaison venait à se formaliser davantage. Outre la valeur heuristique de la notion, l’article permet de s’interroger de manière distanciée sur les formes de « fuite en avant » dénoncées par les opposants à ce genre d’extension, car d’autres projets d’équipements peuvent en découler. Cette même opposition est révélatrice d’un processus de territorialisation, replaçant la phase de consultation d’un document de planification tel que le SCoT comme un temps d’analyse des dynamiques conflictuelles et potentiellement d’évolution de la gouvernance locale. Le potentiel conflictuel s’exprime alors par la capacité d’entraînement ou de mobilisation que peut catalyser ce type de projet contre lui, structurant des collectifs jusqu’alors dispersés et peu fédérés. This article proposes to analyze an old project, which is not necessarily an active controversy but which was put back in the center of the debates by the SCoT Fier-Aravis in 2019. This project is the connection between the areas of ski resorts of La Clusaz and Le Grand Bornand by the Danay mountain, in the Aravis massif. This sector, which is currently not equipped, would make it possible to create a vast linked domain, capable of competing in part with others in the Northern Alps. But this project, in addition to the questions about the intermittence of the discussions concerning it and its feasibility, raises environmental challenges in a massif considered as little equipped until now. It is therefore interesting to question the notion of conflict potential—the basis of which this article proposes to establish—and the risks of environmental conflict arising if the link were to become more formalized. In addition to the heuristic value of the notion, the article allows us to question in a distanced way the forms of “headlong rush” denounced by the opponents of this type of extension, because other equipment projects may result from it. This same opposition is indicative of a process of territorialization, making the consultation phase of an urban planning document such as the SCoT a time for analyzing conflictual dynamics and potentially for the evolution of local governance. The potential for conflict is then expressed through the capacity for mobilization that this type of project can catalyze against it, structuring collectives that were previously dispersed and poorly federated.

Cet article propose de s’intéresser à un vieux projet, qui ne constitue pas nécessairement une controverse « vive » mais qui fut remis au centre des débats par le SCoT Fier-Aravis en 2019. Il s’agit de la liaison entre les domaines skiables de La Clusaz et du Grand Bornand par le Danay, dans le massif des Aravis. Ce secteur actuellement non équipé permettrait d’afficher un vaste domaine relié, en mesure de concurrencer en partie d’autres dans les Alpes du Nord. Mais ce projet, outre les interrogations sur l’intermittence des discussions le concernant et sa faisabilité, suscite des contestations environnementales dans un massif considéré comme peu équipé jusqu’alors. Dès lors, il s’avère intéressant pour questionner la notion de potentiel conflictuel — dont cet article se propose de jeter les bases — et les risques de survenue d’un conflit environnemental si la liaison venait à se formaliser davantage. Outre la valeur heuristique de la notion, l’article permet de s’interroger de manière distanciée sur les formes de « fuite en avant » dénoncées par les opposants à ce genre d’extension, car d’autres projets d’équipements peuvent en découler. Cette même opposition est révélatrice d’un processus de territorialisation, replaçant la phase de consultation d’un document de planification tel que le SCoT comme un temps d’analyse des dynamiques conflictuelles et potentiellement d’évolution de la gouvernance locale. Le potentiel conflictuel s’exprime alors par la capacité d’entraînement ou de mobilisation que peut catalyser ce type de projet contre lui, structurant des collectifs jusqu’alors dispersés et peu fédérés. This article proposes to analyze an old project, which is not necessarily an active controversy but which was put back in the center of the debates by the SCoT Fier-Aravis in 2019. This project is the connection between the areas of ski resorts of La Clusaz and Le Grand Bornand by the Danay mountain, in the Aravis massif. This sector, which is currently not equipped, would make it possible to create a vast linked domain, capable of competing in part with others in the Northern Alps. But this project, in addition to the questions about the intermittence of the discussions concerning it and its feasibility, raises environmental challenges in a massif considered as little equipped until now. It is therefore interesting to question the notion of conflict potential—the basis of which this article proposes to establish—and the risks of environmental conflict arising if the link were to become more formalized. In addition to the heuristic value of the notion, the article allows us to question in a distanced way the forms of “headlong rush” denounced by the opponents of this type of extension, because other equipment projects may result from it. This same opposition is indicative of a process of territorialization, making the consultation phase of an urban planning document such as the SCoT a time for analyzing conflictual dynamics and potentially for the evolution of local governance. The potential for conflict is then expressed through the capacity for mobilization that this type of project can catalyze against it, structuring collectives that were previously dispersed and poorly federated.

Through 2020, Asbury Theological Seminary largely built an introductory course for those preparing for graduate-level study in seminary disciplines. Through that work and the collaborative efforts between our research librarian, Writing Center, and instructional designer, we have discovered shared concerns, knowledge, and new insights into how to help our students. Great synergy was found in terms of information literacy, citations, using information well, and a desire to see students/patrons succeed. Points of divergence were found in terms of organizational structures (siloes) and a potential conflict between a “do for” rather than “teach how” staff focus. Recommendations also are given at the close regarding having writing resources available for patrons in contexts where there is not a writing center.

BACKGROUND The influence of different processing conditions of rapeseed meal on ruminal degradation of crude protein and phytate in dairy cows was investigated. Following oil extraction from the rapeseed, five residence times in the desolventizer/toaster were chosen to remove the solvent from the meal. Rapeseed cake and rapeseed meals were incubated in situ in the rumen of three fistulated dairy cows to determine ruminal degradation parameters. RESULTS With increasing residence time in the desolventizer/toaster the ruminal degradation of crude protein decreased significantly for every treatment step. Ruminal phytate degradation and crude protein degradation were affected almost identically. CONCLUSION The processing conditions of rapeseed meal have a major impact on the ruminal degradation of crude protein and phytate, indicating a potential conflict of interest regarding the production process. Large amounts of undegradable rumen protein are often intended for high-yielding dairy cows whereas a high level of ruminal degradation is preferred for phytate to increase absorption of phosphorus in the small intestine. © 2021 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

PURPOSE To review all case series of refractive corneal inlay implantation: Flexivue (Presbia, Netherlands), Invue (BioVision, Brugg, Switzerland) and Icolens (Neoptics, Hunenberg, Switzerland) performed in presbyopia patients and to evaluate the reported visual outcomes. In addition, our aim is to provide assessment for complications and to report the satisfaction rates. METHODS PubMed, Web of Science and Scopus databases were consulted using "refractive corneal inlay", "Flexivue Inlay", "Invue Inlay" and "Icolens inlay" as keywords. 147 articles were found, and they were assessed considering the inclusion and exclusion criteria. After filtering, this systemic review included ten articles, published between 2011 and 2020. RESULTS 308 eyes from 308 participants were enrolled in this systematic review. Mean maximum follow-up was 13.9 months. Nine of the ten case series included used femtosecond laser for the corneal pocket creation. Mean pocket depth was 293.75 µm. 77.5% of the eyes reported a postoperative uncorrected near visual acuity of 20/32 or better, and 19.20% of the inlay-implanted eyes achieved an uncorrected distance visual acuity of 20/20 or better. The most prominent complications were halos, pain, photophobia, and poor distance visual acuity. 27 eyes (8.7%) had to be explanted due to complications, such as near-distance spectacle dependence or blurred distance vision. CONCLUSION Refractive corneal inlay outcomes demonstrated high efficacy, safety, and satisfaction rates. Furthermore, it is a reversible technique. However, the findings must be viewed with caution due potential conflict of interest. Further research with higher sample size is needed to validate these findings.

espanolUn templo egipcio del siglo II a.C. procedente de las orillas del Nilo, ahora se encuentra en el central parque de la Montana en Ma¬drid. Tras la construccion de la presa de Asuan, que provoco la inundacion de la zona, el templo fue desmantelado y transportado a Madrid en 1970, como agradecimiento por el trabajo de Espana en la proteccion los monumentos de Nubia. En los ultimos tiempos se ha debatido sobre la necesidad de la conservacion material del edificio, planteando la hipotesis, entre otras cosas, de cubiertas protectoras. La tecnica de mover monumentos es muy antigua y el templo de Debod es solo un ejemplo de una larga historia. Po¬demos distinguir los desplazamientos, en los que se mueve el edificio en su totalidad, de los transportes, en los cuales el edificio se desmantela en partes y se reconstruye en otros lugares, como fue el caso del templo de Debod. Este caso es muy comun, al menos en el pasado, pero obviamente mas destructivo. Un enfoque mas maduro se encuentra en la aplicacion de metodos de arqueologia urbana. Sin embargo, la conservacion de los monumentos del pasado siempre ha provocado conflictos con la ciudad del presente, como muestra el caso de la Via dell’Impero, heredada del fascismo, en Roma. Precisamente este caso revela la necesidad de un proyecto que gestione el potencial conflicto entre lo antiguo y lo nuevo. En el templo de Debod ya se han aplicado los tratamientos fisico-quimicos necesarios. Pero la vida de un monumento no es solo la conservacion de piedras o el control del clima. Mas bien, necesitamos comprender el significado del monumento y la relacion con la historia y el espacio en el que se encuentra hoy. EnglishAn Egyptian temple from the 2nd century BC coming from the Nile’s shore is located since 1970 in the very central park of la Montana in Madrid. Following the construction of the Aswan dam, which caused the area to flood, the temple was dismantled and transported as a thanks for Spain’s work on the monuments of Nubia. In recent times, there has been discussions on the need for the material conservation of the building, thinking to protective covers. The technique of moving monuments is very old and the Debod temple is just one example of a long history. We can distinguish the displacements, when the whole building moves, from transport, in which the building is dismantled into parts and rebuilt in other places. This case is very common, at least in the past, but obviously more destructive. A more mature approach is found in the application of the methods of urban archeology. However, the preservation of the monuments of the past has always caused conflicts with the city of the present, as the Via dell’Impero, inherited from fascism, shows in Rome. Precisely this cas reveals the need for a project that manages the potential conflict between old and new. The necessary chemical-physical treatments have already been applied in the temple of Debod. But the life of a monument is not just conservation of stone or climate control. Rather, we need to grasp the significance of the monument and the relationship with history and the space in which it is located today.

The plan to manage and develop Dam Raman ecotourism area in Metro City that takes and utilizes crooked land in the former Purwosari Village (now Purwosari and Purwoasri Sub-districts) has the potential to cause conflicts in the community. Various factors Dam Raman ecotourism area in Metro City that takes and utilizes crooked land in the former Purwosari Village (now Purwosari and Purwoasri Sub-districts) has the potential to cause conflicts in the community. Various factors may influence the effort to realize the construction of the Raman Dam tourist site. What are the important factors that need to be known. Information on important factors in overcoming potential conflict is then needed in order to formulate an appropriate strategy to anticipate conflicts in efforts to develop and manage the Raman Dam Ecotourism area in Metro City in a sustainable manner. This descriptive study chose respondents purposively. Prospective analysis is carried out starting from the identification of important factors, preparation of future scenarios and conflict prevention strategies. The results showed that important factors that need to be considered in efforts to prevent potential conflict management and development of Dam Raman ecotourism areas include; a) Distribution of Fair Income, b) Commitment of Metro City Government, c) Community Participation, d) Institutional, e) Land Status, and f) investors. Conflict prevention strategies should be carried out by taking into account these six important factors from three possible situation scenarios in the future. The best scenario in an effort to prevent conflicts from arising in the management of regional development is the Sai Wawai Scenario.

Il tema delle competenze logiche richieste per capire la matematica è stato quasi sempre oggetto di controversie sul piano educativo, tra i sostenitori dell’insegnamento della logica come disciplina e quelli che la guardano come una competenza trasversale. Il problema viene spesso sollevato nel corso della scuola secondaria di secondo grado e all’inizio dei corsi universitari. In questo contributo si discutono i processi di interpretazione dei testi matematici in linguaggio verbale, e il potenziale conflitto tra i meccanismi interpretativi propri delle notazioni simboliche della matematica e quelli usuali delle lingue. Viene affrontato in particolare il tema dell’interpretazione dei condizionali, anche attraverso l’esame di due teorie opposte. Vengono poi illustrati alcuni esempi a proposito di altri connettivi proposizionali. La conclusione è che la diversità dei processi interpretativi tra lingua e linguaggi della logica sconsiglia di proporre attività che richiedono l’interpretazione logica di testi verbali al di fuori dei contesti in cui questa sia giustificata.

Achieving good welfare of Malayan sun bears (Helarctos malayanus) in captivity through understanding behavioral aspects is crucial in providing improved captive management for conservation purposes. The Malayan sun bear is the smallest bear species and remains the least studied member of the Ursid family. We investigated the behavior patterns of 11 captive sun bears (four cubs, four sub-adults, and three adults) at different time periods (morning, afternoon, and evening). Different behavior pattern were observed between individual bears, and a strong interaction between age grouped and type of behavior were also noticed. We also found that all bear age groups exhibited higher normal behavior than stereotypic behavior. Oral stereotypies were mainly exhibited by cubs, and their locomotor stereotypies were slightly higher in frequency compared to sub-adult and adult individuals. Anticipatory behavior toward keepers during husbandry activities and their potential conflict background may represent a major factor leading to these highly stereotypic behaviors, particularly in cubs and during morning sessions. We suggest that stereotypy can be minimized by providing food or creative tool enrichments to divert the attention of bears from keepers. Minimal stereotypic behavior is crucial in the captive management and conservation of Malayan sun bear, particularly when selecting individual bear to release back to wild habitat.

Even though co‐parenthood is one of the most significant close personal relationships that people can have, there is relatively little philosophical work on the moral duties that co‐parents owe each other. This may be due to the increasingly questionable assumption, still common in our societies, that co‐parenthood arises naturally from marriage or romantic coupledom and thus that commitment to a co‐parent evolves from a commitment to a marital or romantic partner. In this article, we argue that co‐parenthood should be seen as a relationship in its own right, which generates specific moral duties. Co‐parents should come to explicit agreements with each other regarding the most important areas of potential conflict between them. Such agreements may have to be renegotiated over time. We explore some possible non‐negotiable co‐parental duties such as the duties not to alienate the child from the other parent(s) and not to trap a co‐parent in a particularly vulnerable situation. We consider some legal and societal implications of our argument and, finally, suggest some pragmatic benefits of our proposal. (Less)

We examined differences among children in their endorsement of an adult’s claim, their subsequent empirical investigation of that claim, and their resolution of any potential conflict between the claim and their empirical investigation. American and Chinese preschool (N = 171, M = 4.71 years) and elementary school (N = 128, M = 7.59 years) children were presented with five, different-sized, Russian dolls and asked to indicate the heaviest doll. Children typically selected the biggest doll. Children then heard either a false, counter-intuitive claim (i.e., smallest doll = heaviest) or a claim confirming their initial intuition (i.e., biggest doll = heaviest). Children frequently endorsed the experimenter’s claim even when it was counter-intuitive. The experimenter then left the room. During the experimenter’s absence, older children who had heard the counter-intuitive as opposed to the confirming claim explored the dolls more than younger children, especially when subtly prompted to explore. Moreover, only older children who heard the counter-intuitive claim simultaneously picked up the smallest and biggest doll, a more deliberate test of the experimenter’s claim. By implication, children engage in selective exploration following a surprising claim. Older children’s more systematic explorations of what they have been told may reflect improvements in their ability to test such claims and in their greater sensitivity to the fact that unexpected claims can and should be empirically investigated.

It is imperative to enhance the safety of elderly individuals on the roads to ensure the quality of their daily life. Near-miss incidents or accidents at blind intersections often result from a conflict between the behaviors of the driver and of other road users (pedestrians and cyclists). The failure to search for potential conflict in the context of blind intersections is a concern pertaining to road safety. The proposed assistance system performs a proactive braking intervention to achieve a referenced velocity in uncertain situations, such as one in which an unobserved pedestrian might initiate a road crossing. The proactive braking intervention attempts to manage the potential risk of crashing with respect to covert hazards. Because an automated system may impair a human’s ability to perceive and respond to hazardous situations while driving, this study was designed to examine the effects of proactive braking intervention and visual support cues on elderly and younger drivers’ ability to respond to information about potentially hazardous situations. We conducted a public-road driving experiment involving 108 elderly and younger drivers from two non-overlapping age groups. It was observed that the vehicle slowdown realized through the proactive braking intervention enabled the drivers to perform safety confirmation near blind spots and caused them to be more sensitive to and wary of potential hazards. This approach could be effective not only for elderly drivers, but also for young or inexperienced ones.

Background Accrual to cancer clinical trials is suboptimal. Few data exist regarding whether financial reimbursement might increase accruals. Objective The objective of this study was to assess perceptions about reimbursement to overcome barriers to trial accrual. Research design This was a cross-sectional survey. Subjects Oncologists identified from the American Medical Association Physician Masterfile. Measures We report descriptive statistics, associations of physician characteristics with perceptions of reimbursement, domains, and subthemes of free-text comments. Results Respondents (n=1030) were mostly medical oncologists (59.4%), ages 35-54 (67%), and male (75%). Overall, 30% reported discussing trials with >25% of patients. Barriers perceived were administrative/regulatory, physician/staff time, and eligibility criteria. National Cancer Institute cooperative group participants and practice owners were more likely to endorse higher reimbursement. Respondents indicated targeted reimbursement would help improve infrastructure, but also noted potential ethical problems with reimbursement for discussion (40.7%) and accrual (85.9%). Free-text comments addressed reimbursement sources, recipients, and concerns about the real and apparent conflict of interest. Conclusions Though concerns about a potential conflict of interest remain paramount and must be addressed in any new system of reimbursement, oncologists believe reimbursement to enhance infrastructure could help overcome barriers to trial accrual.

Student expectations have increasingly become a focus in Second Language Acquisition research. This study takes a closer look at student teachers’ expectations in a Master of Arts TESOL program at an Australian university to investigate their expectations and sense of fulfillment of these expectations. We employed a sequential explanatory mixed-methods design and conducted a questionnaire (N = 31) and interviews (N = 6) with student teachers. The results show that student teachers expect a well-balanced curriculum of theory and practice and consider teaching practice their top priority. While the expectations of most TESOL student teachers are met, different language profiles can lead to different expectations and potential conflict. Contrary to most previous research, this study showed that unmet expectations do not necessarily lead to unfavorable outcomes because of the student teachers’ ability to adjust in various ways. The study concludes with a discussion of implications for practice and future research.

Social factors hold implications for the success or failure of wildlife reintroductions. Potential conflict issues may prevent projects from proceeding or succeeding. The manner in which wildlife m...

This study identified areas suitable for photovoltaic (PV) and onshore wind systems, with few or no competing land uses. All contiguous land in Japan was classified into 15 independent land-use types according to their regulation level. Four types were determined as soft-restriction areas suitable for development: devastated farmland, grassland, bareland, and scrubland. Legally prohibited land in nature reserves was then excluded from these areas. The remaining area was deemed available for both renewable energy systems. Analysis by geographic information systems (GIS) revealed that the total area of land available for PV and wind turbine development is 3,428 km2 or 0.9% of all contiguous land in Japan. In 72% of this area, these systems may have to compete with other development projects, including each other. Considering factors such as electricity demand and the slope of the land, the installation of onshore wind turbines in areas of competing development is shown to be important. If an onshore wind capacity of 25 GW was to be installed in areas with competing development and a PV capacity of 64 GW in the non-competing areas, it would result in 130.2 TWh/year, which represents 15% of the total annual electricity demand of Japan in 2018.

У статті досліджено теоретико-правові аспекти воєнної сфери в системі державної безпеки України. У ході наукового дослідження з'ясовано, що незалежний розвиток України неможливий без належного забезпечення воєнної сфери, що насамперед напряму пов'язано з низкою складових частин державної безпеки України, зокрема: політичною, економічною, екологічною, соціальною, інформаційною, продовольчою та ін. Лише за умови належного існування воєнної сфери можливе вирішення багатьох завдань щодо забезпечення державної безпеки та створення необхідних умов для стабільного розвитку політичних, економічних, соціальних, екологічних, духовних, інтелектуальних, демографічних засад життєдіяльності суспільства. Воєнна сфера не може досягатися лише за рахунок організації оборони держави, оскільки передбачає ефективні заходи у всіх напрямах життєдіяльності суспільства. У своєму формуванні воєнна сфера залежить від багатьох соціально зумовлених факторів, серед яких важко виокремити головні, оскільки другорядність у забезпеченні воєнної сфери є неприйнятною. Отже, воєнна сфера України як одна з найважливіших складових частин державної безпеки підтримується складним комплексом політичних, економічних, соціальних, військових та інших заходів. Велике значення надається заходам політичного характеру, спрямованим на створення сприятливої для країни зовнішньої та внутрішньої обстановки, зміцнення міжнародного авторитету держави, усунення наявних і потенційних конфліктних ситуацій. Водночас ефективність цих заходів досягається лише за умов, якщо вони збігаються з діями оборонного характеру, які спрямовані на силове стримування можливого агресора та блокування його спроб домогтися політичних цілей за допомогою зброї.

This study argues that the effect of third-party trade on dyadic conflicts is conditional on the naval power of both the potential conflict initiator and its target state. This conditional effect occurs mainly because naval power allows trade-integrated initiators to reduce their trade dependence on a given trade partner and its allies more easily. At the same time, the target’s naval power increases the costs that conflict inflict on the initiator’s trade. As maritime trade accounts for about 80 percent of world trade volume, naval capability has an important effect on combatant states’ ability to substitute trading partners during a conflict and to mitigate trade-related costs, thereby affecting the relationship between third-party trade and conflict. The findings of our statistical analyses support our theoretical expectation that the pacifying effect of third-party trade diminishes as the initiator’s naval power increases, yet increases as the naval power of the potential target increases.

Indonesia is a large nation with a diversity and a lot of its society. In a multicultural society, there is a potential conflict among the nation's children who are at risk of splitting unity and unity. This kind of reality is often found in various democratic contestations in the election of regional chiefs (elections). Religious moderation becomes very important when in a process of democracies emerging identity politics which of course risk injuring democratic values. The purpose of this research is to discuss the effectiveness of religious moderation in realizing the democratic elections (regional election) and the function of political political parties in religious moderation as a pillar of democracy in Indonesia. The method used is research libraries. The conclusion of this research is the first, religious moderation is effective in establishing democratic elections, both political parties serve as a mobilizer for religious moderation to create a dignified and lasting democracy

PurposeThis paper demonstrates that present value (PV) models can be viewed as multiperiod extensions of accrual income statements (AISs). Failure to include AIS details in PV models may lead to inaccurate estimates of earnings and rates of return on assets and equity and inconsistent rankings of mutually exclusive investments. Finally, this paper points out that rankings based on assets and equity earnings and rates of return need not be consistent, requiring financial managers to consider carefully the questions they expect PV models to answer.Design/methodology/approachAISs are used to guide the construction of PV models. Numerical examples illustrate the results. Deductions from AIS definitions demonstrate the potential conflict between asset and equity earnings and rates of return.FindingsPV models can be viewed as multiperiod extensions of AISs. Mutually exclusive rankings based on assets and equity earnings and rates of return need not be consistent.Research limitations/implicationsPV models are sometimes constructed without the details included in AISs. The result of this simplified approach to PV model construction is that earnings and rates of return may be miscalculated and rankings based as asset and equity earnings and rates of return are inconsistent. Tax adjustments for asset and equity earnings may be miscalculated in applied models.Practical implicationsThis paper provides guidelines for properly constructing PV models consistent with AISs.Social implicationsPV models are especially important for small to medium size firms that characterize much of agricultural. Providing a model consistent with AIS construction principles should help financial managers view the linkage between building financial statements and investment analysis.Originality/valueThis is the first paper to develop the idea that the PV model can be viewed as a multiperiod extension of an AIS.

We empirically study how collusion in product markets affects firms' financial disclosure strategies. We find that after a rise in cartel enforcement, U.S. firms start sharing more detailed information in their financial disclosure about their customers, contracts, and products. This new information potentially benefits peers by helping to tacitly coordinate actions in product markets. Indeed, changes in disclosure are associated with higher future profitability. Our results highlight the potential conflict between securities and antitrust regulations.

Accumulation of high-value products in microalgae is not conducive with rapid cell growth, which is the potential conflict in microalgal production. Overcoming such conflict faces numerous challenges in comprehensively understanding cell behavior and metabolism. Here, we show a fully integrated interaction between cell behavior, carbon partitioning, carbon availability and path rate of central carbon metabolism, and have practically overcome the production conflict of Chromochloris zofingiensis. We demonstrate that elevated carbon availability and active path rate of precursors are determinants for product biosynthesis, and the former exhibits a superior potential. As protein content reaches a threshold value to confer survival advantages, carbon availability becomes the major limiting factor for product biosynthesis and cell reproduction. Based on integrated interaction, regulating the C/N balance by feeding carbon source under excess light increases content of high-value products without inhibiting cell growth. Our findings provide a new orientation to achieve great productivity improvements in microalgal production., Sun et al. study the effects of light intensities and C/N ratios on microalgal growth and biomass production. They use chemical and transcriptomic assays to demonstrate that feeding carbon source under excess light increases high-value products without inhibiting cell growth.

The South China Sea Region is one of the largest waters in the world and has a strategic role both in terms of economy, politics and security so as to make this region have great potential that can be utilized by countries around the region. The consequences of many interests in this region is potential conflict form many state. This article analyzes several disputes that occur in the South China Sea based on international law. The purpose of this article is to find out the steps taken by states to resolving these international legal disputes. Through the analysis in this article it was found that in the perspective of international law, the dispute over the South China Sea was sourced from differences of principles in determining maritime boundaries. The analysis of this article also found several steps and efforts that can be taken by the disputing countries to resolve the South China Sea dispute.Keywords : South China Sea; International Dispute; International Law

While we currently witness potential conflict between the United States and Iran, as well as rumblings with North Korea, the post-Cold War international environment continues to observe a sharp dec...

In research on Massively Multiple Online Games and Worlds (MMOs) like World of Warcraft, Everquest or Second Life, the term “worldness” addresses how the various layers of a virtual world--the animated 3D pictorial spectacle, the interactive world of mobile nonplayer characters, the virtual community of other players-- all hang together as an autonomous “world.” This article deploys Bakhtinian concepts of chronotopes operating at different scales to explore the worldness of one such online “world” (Ryzom's Atys). I will show that these different layered chronotopes become visible at moments of crisis. In each crisis, the chronotopic worldness of Atys affords developers and players not only a domain for potential conflict, but also political collaboration and engagement.

Clinical research poses a potential conflict of interest between promoting the goals of the research and protecting the interests of the participants (Brody and Miller 2003; Levinsky 2002; Miller e...

This research examines the conflict prevention between immigrants and the local community in Cisarua, West Java. This research uses a qualitative method with a descriptive approach supported by secondary data. Theories and concepts are used to analyze the conflict prevention between immigrants and local residents in Cisarua, West Java and reveal various factors supporting and inhibiting conflict prevention. This research result shows that potential conflict from the presence of foreign immigrants is still at a low level of conflict escalation and has not yet caused a dangerous situation. The potential for conflict arises from several aspects, such as ideology, socio-cultural, economic, and legal.

Paraneoplastic pemphigus (PNP) is one of the least investigated and rare forms of bullous dermatoses, which comes from underlying neoplasm. The article presents a literature review of dermatologist`s longstanding international experience about etiology, pathogenesis, diagnostics and treatment of this disease. According to the research results of native and foreign authors systematization of modern diagnostic methods of PNP and detectable antigens was performed.Conflict of interest: the authors state that there is no potential conflict of interest requiring disclosure in this article.

This paper describes a clinical case of scalp metastases in the setting of breast cancer. The data on the prevalence of the disease in Russia and the necessity of its early diagnostics is provided. The clinical picture and trichoscopic signs of neoplastic processes in the scalp are presented: alopecia foci of 1–3 cm in diameter; foci older than 6 months featuring erythematous and atrophic skin; nodes of the colour of healthy skin or with a yellowish tint sized 1 cm in diameter; trichoscopy — in the foci older than 6 months, the vascular structures are represented by point, thick and thin tree-like vessels. In connection with a poor prognosis for survival when skin metastases are detected, the onco-alertness of practitioners in relation to scalp metastases should be increased.Conflict of interest: the authors state that there is no potential conflict of interest requiring disclosure in this article.

Erythroderma is a condition damaging at least 80–90 % of the skin surface, characterized by erythema and peeling. This condition may be a manifestation of various diseases of the skin and internal organs, including malignant lymphoproliferative disorders. Sézary syndrome and the erythrodermic variant of mycosis fungoides are aggressive forms of cutaneous T-cell skin lymphoma, the diagnostics of which is challenging due to the similar clinical pictures of these diseases with benign dermatoses. This article presents two clinical cases of erythroderma in the setting of cutaneous T-cell lymphoma. An analysis of the anamnestic data, the clinical picture and the results of laboratory examinations in patients suffering from this condition allowed the diagnosis of Sézary syndrome to be confirmed. The presented cases reflect the importance of identifying the causes of erythroderma.Conflict of interest: the authors state that there is no potential conflict of interest requiring disclosure in this article.

Purpose:to evaluate the efficacy and safety of minocycline in the therapy of medium-heavy and severe forms of acne vulgaris according to modern ideas about pathogenesis of the disease.Materials and methods. Long-term multi-purpose observation which included 28 patients with the established diagnosis of acne vulgaris, medium-weight and severe forms is made. Patients received monotherapy by Minoleksin® medicine, depending on severity — 50–100 mg a day. Prior to the research and after the end of treatment inspection of the patient with calculation the rash elements, clinical and biochemical blood analysis, a research of function of sebaceous glands, the laser scanning microscopy, a laser Doppler floumetry, definition of the dermatological index of quality of life, photography (was performed at the consent of the patient). In the course of therapy inspection of the patient and assessment of tolerance of drug was performed.Results.The evidence of efficiency of minocycline in treatment of vulgar acnes of average and heavy severity is obtained that is confirmed by visual dermatological indicators, non-invasive methods of a research (results of a sebumetriya, the confocal laser scanning microscopy, a Doppler floumetriya), indicators of the dermatological index of quality of life. When studying clinical and laboratory indicators security concerns are not revealed. The undesirable phenomena in the course of the research are not registered.Conclusion.Minolexin® (minocycline) is highly effective and safe drug for treatment of vulgar acnes of average and heavy severity and it can be recommended for practical application in out-patient practice.Conflict of interest: the author states that there is no potential conflict of interest requiring disclosure in this article.