399 results on '"Postma, M. J."'
Search Results
2. Cost-effectiveness of ravulizumab compared with eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria in the Netherlands
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Quist, S. W., Postma, A. J., Myrén, K. J., de Jong, L. A., and Postma, M. J.
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- 2023
- Full Text
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3. Model and Empirical Data-Based Cost-Utility Studies of Continuous Glucose Monitoring in Individuals with Type 1 Diabetes: A Protocol of a Systematic Review on Methodology and Quality
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de Jong, L. A., Li, X., Emamipour, S., van der Werf, S., Postma, M. J., van Dijk, P. R., and Feenstra, T. L.
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- 2023
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4. “Cost-effectiveness of ACL treatment is dependent on age and activity level: a systematic review”
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Deviandri, R., van der Veen, H. C., Lubis, A. M. T., van den Akker-Scheek, I., and Postma, M. J.
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- 2023
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5. Health-economic evaluation of meniscus tear treatments: a systematic review
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Deviandri, R., Daulay, M. C., Iskandar, D., Kautsar, A. P., Lubis, A. M. T., and Postma, M. J.
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- 2023
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6. Cost-minimisation analysis of a treat-and-extend regimen with anti-VEGFs in patients with neovascular age-related macular degeneration
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Quist, S. W., de Jong, L. A., van Asten, F., Knoester, P., Postma, M. J., and Freriks, R. D.
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- 2022
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7. Correction to: “Cost-effectiveness of ACL treatment is dependent on age and activity level: a systematic review”
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Deviandri, R., van der Veen, H. C., Lubis, A. M. T., van den Akker-Scheek, I., and Postma, M. J.
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- 2023
- Full Text
- View/download PDF
8. Implementing a Managed Entry Agreement Framework in Cyprus
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Pitsillidou, Olga, primary, Petrou, Panagiotis, additional, and Postma, M. J., additional
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- 2023
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9. Clinical pharmacy services for tuberculosis management: a systematic review
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Iskandar, D., primary, Suryanegara, F. D. A., additional, van Boven, J. F. M., additional, and Postma, M. J., additional
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- 2023
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10. Quantifying the impact of mass vaccination programmes on notified cases in the Netherlands
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van Wijhe, M., Tulen, A. D., Altes, H. Korthals, McDonald, S. A., de Melker, H. E., Postma, M. J., and Wallinga, J.
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- 2018
11. Cost-Effectiveness of Scaling Up Modern Family Planning Interventions in Low- and Middle-Income Countries: An Economic Modeling Analysis in Indonesia and Uganda
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Zakiyah, Neily, van Asselt, A. D. I., Setiawan, D., Cao, Q., Roijmans, F., and Postma, M. J.
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- 2019
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12. Do Costs of Varicella Justify Routine Infant Vaccination? Pharmacoeconomic and Clinical Considerations
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Postma, M. J., Bos, J. M., Welte, R., de Groot, R., Luytjes, W., Rümke, H. C., and Beutels, P.
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- 2004
13. Exploratory Analysis of the Economically Justifiable Price of a Hypothetical RSV Vaccine for Older Adults in the Netherlands and the United Kingdom
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Zeevat, F, Luttjeboer, J, Paulissen, J H J, van der Schans, J, Beutels, P, Boersma, C, Postma, M J, Nair, Harish, Campbell, Harry, Openshaw, Peter, Beutels, Philippe, Bont, Louis, Pollard, Andrew, Molero, Eva, Martinon-Torres, Federico, Heikkinen, Terho, Meijer, Adam, Kølsen Fischer, Thea, van den Berge, Maarten, Giaquinto, Carlo, Kieffer, Alexia, Demont, Clarisse, Gallichan, Scott, Dormitzer, Philip, Leach, Amanda, Dillon, Laura, Aerssens, Jeroen, Rosen, Brian, RESCEU Investigators, Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), and Microbes in Health and Disease (MHD)
- Subjects
Rsv vaccine ,business.industry ,Cost effectiveness ,Incidence (epidemiology) ,MEDLINE ,The Netherlands ,Exploratory analysis ,United Kingdom ,Vaccination ,Infectious Diseases ,Elderly ,Older adults ,Preventive intervention ,Immunology and Allergy ,Medicine ,Cost-effectiveness ,Human medicine ,Respiratory Syncytial Virus ,business ,Biology ,health care economics and organizations ,RSV Vaccines ,Demography - Abstract
Background In older adults, the burden of respiratory syncytial virus (RSV) resembles that of influenza and may even be considered worse due to the lack of preventive interventions. This study was performed to identify the available literature on RSV infection in older adults, and to provide updated exploratory results of the cost-effectiveness of a hypothetical RSV vaccine in the Netherlands and the United Kingdom. Methods A literature search was performed in Medline and EMBASE on 11 November 2019, which served as input for a static decision-tree model that was used to estimate the EJP, for an RSV vaccine applying different willingness-to-pay (WTP) thresholds. WTP thresholds applied were €20 000 and €50 000 per quality-adjusted life-year for the Netherlands, and £20 000 and £30 000 per quality-adjusted life-year for the United Kingdom. Analyses were—in line with country-specific guidelines—conducted from a societal perspective for the Netherlands and a third-party payer perspective for the United Kingdom. The robustness of the cost-effectiveness results was tested in sensitivity analysis. Results After screening the literature, 3 studies for the Netherlands and 6 for the United Kingdom remained to populate the country-specific models. In the base case analysis for the Netherlands (mean RSV incidence, 3.32%), justifiable vaccine prices of €16.38 and €50.03 were found, based on applying the lower and higher WTP thresholds, respectively. Similarly, for the United Kingdom (mean incidence, 7.13%), vaccine prices of £72.29 and £109.74 were found, respectively. Conclusion RSV vaccination may well be cost-effective in both the Netherlands and the United Kingdom, depending on the exact RSV incidence, vaccine effectiveness and price. However, sensitivity analysis showed that the results were robust based on varying the different parameter estimates and assumptions. With RSV vaccines reaching the final stages of development, a strong need exists for cost-effectiveness studies to understand economically justifiable pricing of the vaccine.
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- 2022
14. Estimating Influenza-Related Hospitalization in the Netherlands
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Reinders, A., Sprenger, M. J. W., Postma, M. J., Jager, J. C., and Leidl, R. M.
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- 1998
15. Correction to: “Cost-effectiveness of ACL treatment is dependent on age and activity level: a systematic review”
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Deviandri, R., primary, van der Veen, H. C., additional, Lubis, A. M. T., additional, van den Akker-Scheek, I., additional, and Postma, M. J., additional
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- 2022
- Full Text
- View/download PDF
16. “Cost-effectiveness of ACL treatment is dependent on age and activity level: a systematic review”
- Author
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Deviandri, R., primary, van der Veen, H. C., additional, Lubis, A. M. T., additional, van den Akker-Scheek, I., additional, and Postma, M. J., additional
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- 2022
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17. Burden of early, advanced and metastatic breast cancer in The Netherlands
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Vondeling, G. T., Menezes, G. L., Dvortsin, E. P., Jansman, F. G. A., Konings, I. R., Postma, M. J., and Rozenbaum, M. H.
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- 2018
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18. Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the global burden of disease study 2020, release 1
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Galles N. C., Liu P. Y., Updike R. L., Fullman N., Nguyen J., Rolfe S., Sbarra A. N., Schipp M. F., Marks A., Abady G. G., Abbas K. M., Abbasi S. W., Abbastabar H., Abd-Allah F., Abdoli A., Abolhassani H., Abosetugn A. E., Adabi M., Adamu A. A., Adetokunboh O. O., Adnani Q. E. S., Advani S. M., Afzal S., Aghamir S. M. K., Ahinkorah B. O., Ahmad S., Ahmad T., Ahmadi S., Ahmed H., Ahmed M. B., Ahmed Rashid T., Ahmed Salih Y., Akalu Y., Aklilu A., Akunna C. J., Al Hamad H., Alahdab F., Albano L., Alemayehu Y., Alene K. A., Al-Eyadhy A., Alhassan R. K., Ali L., Aljunid S. M., Almustanyir S., Altirkawi K. A., Alvis-Guzman N., Amu H., Andrei C. L., Andrei T., Ansar A., Ansari-Moghaddam A., Antonazzo I. C., Antony B., Arabloo J., Arab-Zozani M., Artanti K. D., Arulappan J., Awan A. T., Awoke M. A., Ayza M. A., Azarian G., Azzam A. Y., B D. B., Babar Z. -U. -D., Balakrishnan S., Banach M., Bante S. A., Barnighausen T. W., Barqawi H. J., Barrow A., Bassat Q., Bayarmagnai N., Bejarano Ramirez D. F., Bekuma T. T., Belay H. G., Belgaumi U. I., Bhagavathula A. S., Bhandari D., Bhardwaj N., Bhardwaj P., Bhaskar S., Bhattacharyya K., Bibi S., Bijani A., Biondi A., Boloor A., Braithwaite D., Buonsenso D., Butt Z. A., Camargos P., Carreras G., Carvalho F., Castaneda-Orjuela C. A., Chakinala R. C., Charan J., Chatterjee S., Chattu S. K., Chattu V. K., Chowdhury F. R., Christopher D. J., Chu D. -T., Chung S. -C., Cortesi P. A., Costa V. M., Couto R. A. S., Dadras O., Dagnew A. B., Dagnew B., Dai X., Dandona L., Dandona R., De Neve J. -W., Derbew Molla M., Derseh B. T., Desai R., Desta A. A., Dhamnetiya D., Dhimal M. L., Dhimal M., Dianatinasab M., Diaz D., Djalalinia S., Dorostkar F., Edem B., Edinur H. A., Eftekharzadeh S., El Sayed I., El Sayed Zaki M., Elhadi M., El-Jaafary S. I., Elsharkawy A., Enany S., Erkhembayar R., Esezobor C. I., Eskandarieh S., Ezeonwumelu I. J., Ezzikouri S., Fares J., Faris P. S., Feleke B. E., Ferede T. Y., Fernandes E., Fernandes J. C., Ferrara P., Filip I., Fischer F., Francis M. R., Fukumoto T., Gad M. M., Gaidhane S., Gallus S., Garg T., Geberemariyam B. S., Gebre T., Gebregiorgis B. G., Gebremedhin K. B., Gebremichael B., Gessner B. D., Ghadiri K., Ghafourifard M., Ghashghaee A., Gilani S. A., Glavan I. -R., Glushkova E. V., Golechha M., Gonfa K. B., Gopalani S. V., Goudarzi H., Gubari M. I. M., Guo Y., Gupta V. B., Gupta V. K., Gutierrez R. A., Haeuser E., Halwani R., Hamidi S., Hanif A., Haque S., Harapan H., Hargono A., Hashi A., Hassan S., Hassanein M. H., Hassanipour S., Hassankhani H., Hay S. I., Hayat K., Hegazy M. I., Heidari G., Hezam K., Holla R., Hoque M. E., Hosseini M., Hosseinzadeh M., Hostiuc M., Househ M., Hsieh V. C. -R., Huang J., Humayun A., Hussain R., Hussein N. R., Ibitoye S. E., Ilesanmi O. S., Ilic I. M., Ilic M. D., Inamdar S., Iqbal U., Irham L. M., Irvani S. S. N., Islam S. M. S., Ismail N. E., Itumalla R., Jha R. P., Joukar F., Kabir A., Kabir Z., Kalhor R., Kamal Z., Kamande S. M., Kandel H., Karch A., Kassahun G., Kassebaum N. J., Katoto P. D., Kelkay B., Kengne A. P., Khader Y. S., Khajuria H., Khalil I. A., Khan E. A., Khan G., Khan J., Khan M., Khan M. A., Khang Y. -H., Khoja A. T., Khubchandani J., Kim G. R., Kim M. S., Kim Y. J., Kimokoti R. W., Kisa A., Kisa S., Korshunov V. A., Kosen S., Kuate Defo B., Kulkarni V., Kumar A., Kumar G. A., Kumar N., Kwarteng A., La Vecchia C., Lami F. H., Landires I., Lasrado S., Lassi Z. S., Lee H., Lee Y. Y., Levi M., Lewycka S., Li S., Liu X., Lobo S. W., Lopukhov P. D., Lozano R., Lutzky Saute R., Magdy Abd El Razek M., Makki A., Malik A. A., Mansour-Ghanaei F., Mansournia M. A., Mantovani L. G., Martins-Melo F. R., Matthews P. C., Medina J. R. C., Mendoza W., Menezes R. G., Mengesha E. W., Meretoja T. J., Mersha A. G., Mesregah M. K., Mestrovic T., Miazgowski B., Milne G. J., Mirica A., Mirrakhimov E. M., Mirzaei H. R., Misra S., Mithra P., Moghadaszadeh M., Mohamed T. A., Mohammad K. A., Mohammad Y., Mohammadi M., Mohammadian-Hafshejani A., Mohammed A., Mohammed S., Mohapatra A., Mokdad A. H., Molokhia M., Monasta L., Moni M. A., Montasir A. A., Moore C. E., Moradi G., Moradzadeh R., Moraga P., Mueller U. O., Munro S. B., Naghavi M., Naimzada M. D., Naveed M., Nayak B. P., Negoi I., Neupane Kandel S., Nguyen T. H., Nikbakhsh R., Ningrum D. N. A., Nixon M. R., Nnaji C. A., Noubiap J. J., Nunez-Samudio V., Nwatah V. E., Oancea B., Ochir C., Ogbo F. A., Olagunju A. T., Olakunde B. O., Onwujekwe O. E., Otstavnov N., Otstavnov S. S., Owolabi M. O., Padubidri J. R., Pakshir K., Park E. -C., Pashazadeh Kan F., Pathak M., Paudel R., Pawar S., Pereira J., Peres M. F. P., Perianayagam A., Pinheiro M., Pirestani M., Podder V., Polibin R. V., Pollok R. C. G., Postma M. J., Pottoo F. H., Rabiee M., Rabiee N., Radfar A., Rafiei A., Rahimi-Movaghar V., Rahman M., Rahmani A. M., Rahmawaty S., Rajesh A., Ramshaw R. E., Ranasinghe P., Rao C. R., Rao S. J., Rathi P., Rawaf D. L., Rawaf S., Renzaho A. M. N., Rezaei N., Rezai M. S., Rios-Blancas M., Rogowski E. L. B., Ronfani L., Rwegerera G. M., Saad A. M., Sabour S., Saddik B., Saeb M. R., Saeed U., Sahebkar A., Sahraian M. A., Salam N., Salimzadeh H., Samaei M., Samy A. M., Sanabria J., Sanmarchi F., Santric-Milicevic M. M., Sartorius B., Sarveazad A., Sathian B., Sawhney M., Saxena D., Saxena S., Seidu A. -A., Seylani A., Shaikh M. A., Shamsizadeh M., Shetty P. H., Shigematsu M., Shin J. I., Sidemo N. B., Singh A., Singh J. A., Sinha S., Skryabin V. Y., Skryabina A. A., Soheili A., Tadesse E. G., Tamiru A. T., Tan K. -K., Tekalegn Y., Temsah M. -H., Thakur B., Thapar R., Thavamani A., Tobe-Gai R., Tohidinik H. R., Tovani-Palone M. R., Traini E., Tran B. X., Tripathi M., Tsegaye B., Tsegaye G. W., Ullah A., Ullah S., Unim B., Vacante M., Velazquez D. Z., Vo B., Vollmer S., Vu G. T., Vu L. G., Waheed Y., Winkler A. S., Wiysonge C. S., Yigit V., Yirdaw B. W., Yon D. K., Yonemoto N., Yu C., Yuce D., Yunusa I., Zamani M., Zamanian M., Zewdie D. T., Zhang Z. -J., Zhong C., Zumla A., Murray C. J. L., Lim S. S., Mosser J. F., Aghamir S., Sahraian M., Mansournia M., Mirzaei H., Temsah M., Andrei C., Glavan I., Antonazzo I., Singh Mtech A., Padubidri J., Babar Z., De Neve J., Noubiap J., Chakinala R., Chattu S., Chattu V., Chu D., Chung S., Kumar G., Gilani S., Gupta V., Hargono Dr A., Islam S., Hsieh V., Irvani S. N., Ismail N., Khang Y., Yon D., Kim G., Park E., Shin J., Kim M., Kim Y., Lee Y., Medina J. C., Naimzada M., Rahmani A., Rezai M., Rao S., Saeb M., Seidu A., Tan K., Tohidinik H., Zhang Z., Galles, N, Liu, P, Updike, R, Fullman, N, Nguyen, J, Rolfe, S, Sbarra, A, Schipp, M, Marks, A, Abady, G, Abbas, K, Abbasi, S, Abbastabar, H, Abd-Allah, F, Abdoli, A, Abolhassani, H, Abosetugn, A, Adabi, M, Adamu, A, Adetokunboh, O, Adnani, Q, Advani, S, Afzal, S, Aghamir, S, Ahinkorah, B, Ahmad, S, Ahmad, T, Ahmadi, S, Ahmed, H, Ahmed, M, Ahmed Rashid, T, Ahmed Salih, Y, Akalu, Y, Aklilu, A, Akunna, C, Al Hamad, H, Alahdab, F, Albano, L, Alemayehu, Y, Alene, K, Al-Eyadhy, A, Alhassan, R, Ali, L, Aljunid, S, Almustanyir, S, Altirkawi, K, Alvis-Guzman, N, Amu, H, Andrei, C, Andrei, T, Ansar, A, Ansari-Moghaddam, A, Antonazzo, I, Antony, B, Arabloo, J, Arab-Zozani, M, Artanti, K, Arulappan, J, Awan, A, Awoke, M, Ayza, M, Azarian, G, Azzam, A, B, D, Babar, Z, Balakrishnan, S, Banach, M, Bante, S, Barnighausen, T, Barqawi, H, Barrow, A, Bassat, Q, Bayarmagnai, N, Bejarano Ramirez, D, Bekuma, T, Belay, H, Belgaumi, U, Bhagavathula, A, Bhandari, D, Bhardwaj, N, Bhardwaj, P, Bhaskar, S, Bhattacharyya, K, Bibi, S, Bijani, A, Biondi, A, Boloor, A, Braithwaite, D, Buonsenso, D, Butt, Z, Camargos, P, Carreras, G, Carvalho, F, Castaneda-Orjuela, C, Chakinala, R, Charan, J, Chatterjee, S, Chattu, S, Chattu, V, Chowdhury, F, Christopher, D, Chu, D, Chung, S, Cortesi, P, Costa, V, Couto, R, Dadras, O, Dagnew, A, Dagnew, B, Dai, X, Dandona, L, Dandona, R, De Neve, J, Derbew Molla, M, Derseh, B, Desai, R, Desta, A, Dhamnetiya, D, Dhimal, M, Dianatinasab, M, Diaz, D, Djalalinia, S, Dorostkar, F, Edem, B, Edinur, H, Eftekharzadeh, S, El Sayed, I, El Sayed Zaki, M, Elhadi, M, El-Jaafary, S, Elsharkawy, A, Enany, S, Erkhembayar, R, Esezobor, C, Eskandarieh, S, Ezeonwumelu, I, Ezzikouri, S, Fares, J, Faris, P, Feleke, B, Ferede, T, Fernandes, E, Fernandes, J, Ferrara, P, Filip, I, Fischer, F, Francis, M, Fukumoto, T, Gad, M, Gaidhane, S, Gallus, S, Garg, T, Geberemariyam, B, Gebre, T, Gebregiorgis, B, Gebremedhin, K, Gebremichael, B, Gessner, B, Ghadiri, K, Ghafourifard, M, Ghashghaee, A, Gilani, S, Glavan, I, Glushkova, E, Golechha, M, Gonfa, K, Gopalani, S, Goudarzi, H, Gubari, M, Guo, Y, Gupta, V, Gutierrez, R, Haeuser, E, Halwani, R, Hamidi, S, Hanif, A, Haque, S, Harapan, H, Hargono, A, Hashi, A, Hassan, S, Hassanein, M, Hassanipour, S, Hassankhani, H, Hay, S, Hayat, K, Hegazy, M, Heidari, G, Hezam, K, Holla, R, Hoque, M, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Househ, M, Hsieh, V, Huang, J, Humayun, A, Hussain, R, Hussein, N, Ibitoye, S, Ilesanmi, O, Ilic, I, Ilic, M, Inamdar, S, Iqbal, U, Irham, L, Irvani, S, Islam, S, Ismail, N, Itumalla, R, Jha, R, Joukar, F, Kabir, A, Kabir, Z, Kalhor, R, Kamal, Z, Kamande, S, Kandel, H, Karch, A, Kassahun, G, Kassebaum, N, Katoto, P, Kelkay, B, Kengne, A, Khader, Y, Khajuria, H, Khalil, I, Khan, E, Khan, G, Khan, J, Khan, M, Khang, Y, Khoja, A, Khubchandani, J, Kim, G, Kim, M, Kim, Y, Kimokoti, R, Kisa, A, Kisa, S, Korshunov, V, Kosen, S, Kuate Defo, B, Kulkarni, V, Kumar, A, Kumar, G, Kumar, N, Kwarteng, A, La Vecchia, C, Lami, F, Landires, I, Lasrado, S, Lassi, Z, Lee, H, Lee, Y, Levi, M, Lewycka, S, Li, S, Liu, X, Lobo, S, Lopukhov, P, Lozano, R, Lutzky Saute, R, Magdy Abd El Razek, M, Makki, A, Malik, A, Mansour-Ghanaei, F, Mansournia, M, Mantovani, L, Martins-Melo, F, Matthews, P, Medina, J, Mendoza, W, Menezes, R, Mengesha, E, Meretoja, T, Mersha, A, Mesregah, M, Mestrovic, T, Miazgowski, B, Milne, G, Mirica, A, Mirrakhimov, E, Mirzaei, H, Misra, S, Mithra, P, Moghadaszadeh, M, Mohamed, T, Mohammad, K, Mohammad, Y, Mohammadi, M, Mohammadian-Hafshejani, A, Mohammed, A, Mohammed, S, Mohapatra, A, Mokdad, A, Molokhia, M, Monasta, L, Moni, M, Montasir, A, Moore, C, Moradi, G, Moradzadeh, R, Moraga, P, Mueller, U, Munro, S, Naghavi, M, Naimzada, M, Naveed, M, Nayak, B, Negoi, I, Neupane Kandel, S, Nguyen, T, Nikbakhsh, R, Ningrum, D, Nixon, M, Nnaji, C, Noubiap, J, Nunez-Samudio, V, Nwatah, V, Oancea, B, Ochir, C, Ogbo, F, Olagunju, A, Olakunde, B, Onwujekwe, O, Otstavnov, N, Otstavnov, S, Owolabi, M, Padubidri, J, Pakshir, K, Park, E, Pashazadeh Kan, F, Pathak, M, Paudel, R, Pawar, S, Pereira, J, Peres, M, Perianayagam, A, Pinheiro, M, Pirestani, M, Podder, V, Polibin, R, Pollok, R, Postma, M, Pottoo, F, Rabiee, M, Rabiee, N, Radfar, A, Rafiei, A, Rahimi-Movaghar, V, Rahman, M, Rahmani, A, Rahmawaty, S, Rajesh, A, Ramshaw, R, Ranasinghe, P, Rao, C, Rao, S, Rathi, P, Rawaf, D, Rawaf, S, Renzaho, A, Rezaei, N, Rezai, M, Rios-Blancas, M, Rogowski, E, Ronfani, L, Rwegerera, G, Saad, A, Sabour, S, Saddik, B, Saeb, M, Saeed, U, Sahebkar, A, Sahraian, M, Salam, N, Salimzadeh, H, Samaei, M, Samy, A, Sanabria, J, Sanmarchi, F, Santric-Milicevic, M, Sartorius, B, Sarveazad, A, Sathian, B, Sawhney, M, Saxena, D, Saxena, S, Seidu, A, Seylani, A, Shaikh, M, Shamsizadeh, M, Shetty, P, Shigematsu, M, Shin, J, Sidemo, N, Singh, A, Singh, J, Sinha, S, Skryabin, V, Skryabina, A, Soheili, A, Tadesse, E, Tamiru, A, Tan, K, Tekalegn, Y, Temsah, M, Thakur, B, Thapar, R, Thavamani, A, Tobe-Gai, R, Tohidinik, H, Tovani-Palone, M, Traini, E, Tran, B, Tripathi, M, Tsegaye, B, Tsegaye, G, Ullah, A, Ullah, S, Unim, B, Vacante, M, Velazquez, D, Vo, B, Vollmer, S, Vu, G, Vu, L, Waheed, Y, Winkler, A, Wiysonge, C, Yigit, V, Yirdaw, B, Yon, D, Yonemoto, N, Yu, C, Yuce, D, Yunusa, I, Zamani, M, Zamanian, M, Zewdie, D, Zhang, Z, Zhong, C, Zumla, A, Murray, C, Lim, S, Mosser, J, Singh Mtech, A, Hargono Dr, A, Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Microbes in Health and Disease (MHD), Tampere University, Health Sciences, HUS Comprehensive Cancer Center, University of Helsinki, Helsinki University Hospital Area, Abbas, Kaja [0000-0003-0563-1576], Veritati - Repositório Institucional da Universidade Católica Portuguesa, and GBD 2020, Release 1, Vaccine Coverage Collaborators
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Vaccine coverage ,Vacunación de rutina ,Time Factors ,Vaccination Coverage ,Global Plan of Action on Vaccines ,Service delivery framework ,IMPACT ,Global Health ,Cobertura de vacunas ,Routine childhood vaccination ,Global Burden of Disease ,Public Health ,Underserved Population ,Polio vaccine ,0302 clinical medicine ,WORLDWIDE ,Routine immunisation ,Global health ,Medicine ,030212 general & internal medicine ,Child ,11 Medical and Health Sciences ,General Medicine ,Articles ,childhood vaccination, GBD ,Plan de Acción Mundial sobre Vacunas ,3142 Public health care science, environmental and occupational health ,3. Good health ,ddc ,Vaccination ,Poliovirus Vaccines ,Action plan ,Life Sciences & Biomedicine ,Vacunación infantil ,MED/42 - IGIENE GENERALE E APPLICATA ,030231 tropical medicine ,Measles Vaccine ,03 medical and health sciences ,Medicine, General & Internal ,Environmental health ,General & Internal Medicine ,Humans ,IMMUNIZATION COVERAGE ,VALIDITY ,Vaccination approaches ,PROGRESS ,Diphtheria-Tetanus-Pertussis Vaccine ,CONFLICT ,Equity (economics) ,Science & Technology ,business.industry ,MORTALITY ,GBD 2020, Release 1, Vaccine Coverage Collaborators ,Global burden of disease, injury and risk factors ,Child vaccination ,Global vaccine policies ,Políticas mundiales de vacunación ,Carga global de enfermedades, lesiones y factores de riesgo ,Global vaccination policies ,3121 General medicine, internal medicine and other clinical medicine ,Childhood vaccination ,Measles vaccine ,Routine vaccination ,business ,Vaccine programme implementation - Abstract
Medir la vacunación infantil de rutina es crucial para informar las políticas mundiales de vacunación y la implementación de programas, y para hacer un seguimiento del progreso hacia los objetivos establecidos por el Plan de Acción Mundial sobre Vacunas (GVAP) y la Agenda de Inmunización 2030. Se necesitan estimaciones sólidas de la cobertura de vacunación de rutina para identificar los éxitos pasados y persistentes. vulnerabilidades. A partir del Estudio de la carga global de enfermedades, lesiones y factores de riesgo (GBD) 2020, versión 1, realizamos un análisis sistemático de las tendencias de cobertura de vacunas a nivel mundial, regional y nacional utilizando un marco estadístico, por vacuna y a lo largo del tiempo. Métodos Para este análisis recopilamos 55 326 observaciones específicas del país, de la cohorte, del año, de la vacuna y de la dosis de la cobertura de vacunación infantil de rutina entre 1980 y 2019. Utilizando el proceso de regresión gaussiana espaciotemporal, Estimaciones específicas por año de 11 indicadores de cobertura de vacunación infantil de rutina para 204 países y territorios desde 1980 hasta 2019, ajustando los sesgos en los datos informados por los países y reflejando los desabastecimientos informados y las interrupciones en el suministro. Analizamos las tendencias mundiales y regionales en la cobertura y el número de niños con dosis cero (definidos como aquellos que nunca recibieron una dosis de vacuna contra la difteria, el tétanos y la tos ferina [DTP]), el progreso hacia los objetivos del GVAP y la relación entre la cobertura de la vacuna y el desarrollo sociodemográfico. Recomendaciones Para 2019, la cobertura mundial de la tercera dosis de DTP (DTP3; 81,6 % [intervalo de incertidumbre del 95 % 80,4–82,7]) se duplicó con creces con respecto a los niveles estimados en 1980 (39,9 % [37,5–42 ·1]), al igual que la cobertura mundial de la vacuna antisarampionosa de primera dosis (MCV1; del 38,5 % [35,4–41,3] en 1980 al 83,6 % [82,3–84,8 ] en 2019). La cobertura de la vacuna antipoliomielítica de tercera dosis (Pol3) también aumentó, del 42,6 % (41,4–44,1) en 1980 al 79,8 % (78,4–81,1) en 2019, y la cobertura mundial de vacunas más nuevas Las vacunas aumentaron rápidamente entre 2000 y 2019. La cantidad mundial de niños que recibieron dosis cero se redujo en casi un 75 % entre 1980 y 2019, de 56,8 millones (52,6–60,9) a 14,5 millones (13,4– 15·9). Sin embargo, durante la última década, la cobertura mundial de vacunas se estabilizó en general; 94 países y territorios registraron una disminución de la cobertura de DTP3 desde 2010. Se estimó que solo 11 países y territorios alcanzaron el objetivo nacional del GVAP de al menos una cobertura del 90 % para todas las vacunas evaluadas en 2019. Interpretación Después de lograr grandes avances en la cobertura de vacunación infantil en todo el mundo, en gran parte del mundo este progreso se estancó o se revirtió de 2010 a 2019. Estos hallazgos subrayan la importancia de revisar las estrategias de inmunización de rutina y los enfoques programáticos, centrando la prestación de servicios en torno a la equidad y las poblaciones desatendidas. Fortalecer los datos de vacunas y los sistemas de monitoreo es crucial para estas actividades, ahora y hasta 2030, para garantizar que todos los niños tengan acceso y puedan beneficiarse de las vacunas que salvan vidas. Measuring routine childhood vaccination is crucial to inform global vaccine policies and programme implementation, and to track progress towards targets set by the Global Vaccine Action Plan (GVAP) and Immunization Agenda 2030. Robust estimates of routine vaccine coverage are needed to identify past successes and persistent vulnerabilities. Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020, Release 1, we did a systematic analysis of global, regional, and national vaccine coverage trends using a statistical framework, by vaccine and over time. Methods For this analysis we collated 55 326 country-specific, cohort-specific, year-specific, vaccine-specific, and dose-specific observations of routine childhood vaccination coverage between 1980 and 2019. Using spatiotemporal Gaussian process regression, we produced location-specific and year-specific estimates of 11 routine childhood vaccine coverage indicators for 204 countries and territories from 1980 to 2019, adjusting for biases in country-reported data and reflecting reported stockouts and supply disruptions. We analysed global and regional trends in coverage and numbers of zero-dose children (defined as those who never received a diphtheria-tetanus-pertussis [DTP] vaccine dose), progress towards GVAP targets, and the relationship between vaccine coverage and sociodemographic development. Findings By 2019, global coverage of third-dose DTP (DTP3; 81·6% [95% uncertainty interval 80·4–82·7]) more than doubled from levels estimated in 1980 (39·9% [37·5–42·1]), as did global coverage of the first-dose measles-containing vaccine (MCV1; from 38·5% [35·4–41·3] in 1980 to 83·6% [82·3–84·8] in 2019). Third-dose polio vaccine (Pol3) coverage also increased, from 42·6% (41·4–44·1) in 1980 to 79·8% (78·4–81·1) in 2019, and global coverage of newer vaccines increased rapidly between 2000 and 2019. The global number of zero-dose children fell by nearly 75% between 1980 and 2019, from 56·8 million (52·6–60·9) to 14·5 million (13·4–15·9). However, over the past decade, global vaccine coverage broadly plateaued; 94 countries and territories recorded decreasing DTP3 coverage since 2010. Only 11 countries and territories were estimated to have reached the national GVAP target of at least 90% coverage for all assessed vaccines in 2019. Interpretation After achieving large gains in childhood vaccine coverage worldwide, in much of the world this progress was stalled or reversed from 2010 to 2019. These findings underscore the importance of revisiting routine immunisation strategies and programmatic approaches, recentring service delivery around equity and underserved populations. Strengthening vaccine data and monitoring systems is crucial to these pursuits, now and through to 2030, to ensure that all children have access to, and can benefit from, lifesaving vaccines.
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19. Concluding remarks
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van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., Albers, C. E. S., van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., and Albers, C. E. S.
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20. Baseline analysis of the economic impact of HIV / AIDS 1982–1991
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van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., Albers, C. E. S., van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., and Albers, C. E. S.
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21. Health care and medical technology
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van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., Albers, C. E. S., van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., and Albers, C. E. S.
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22. Risk behaviour and the spread of HIV
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van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., Albers, C. E. S., van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., and Albers, C. E. S.
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23. The response to AIDS: strategies for AIDS control and care
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van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., Albers, C. E. S., van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., and Albers, C. E. S.
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24. Reference scenario: Impact of AIDS in 1995 and 2000
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van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., Albers, C. E. S., van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., and Albers, C. E. S.
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25. Scenario construction
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van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., Albers, C. E. S., van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., and Albers, C. E. S.
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26. Scenario project 'The sociocultural and economic impact of AIDS: design and working plan'
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van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., Albers, C. E. S., van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., and Albers, C. E. S.
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27. Baseline analysis of sociocultural aspects of AIDS: 1982-1991
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van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., Albers, C. E. S., van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., and Albers, C. E. S.
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28. Baseline analysis HIV / AIDS in the Netherlands: 1982-1991
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van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., Albers, C. E. S., van den Boom, F. M. L. G., Jager, J. C., Reinking, D. P., Postma, M. J., and Albers, C. E. S.
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29. Cost-Effectiveness of HIV NAT Screening for Dutch Donors
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Postma, M. J., Los, A. P. M., Ruitenberg, E. J., Sibinga, C. Th. Smit, Sibinga, C. Th. Smit, editor, and Cash, J. D., editor
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30. Assessing performance of the Healthcare Access and Quality Index, overall and by select age groups, for 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019
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Bala, Hamiduzzaman, Mohammad, Hanif, Asif, Haro, Josep Maria, Hasaballah, Ahmed I, Hasan, Md Mehedi, Hasan, M Tasdik, Hashi, Abdiwahab, Hay, Simon I, Hayat, Khezar, Heidari, Mohammad, Heidari, Golnaz, Henry, Nathaniel J, Herteliu, Claudiu, Holla, Ramesh, Hossain, Sahadat, Hossain, Sheikh Jamal, Hossain, Mohammad Bellal Hossain, Hosseinzadeh, Mehdi, Hostiuc, Sorin, Hoveidamanesh, Soodabeh, Hsieh, Vivian Chia-rong, Hu, Guoqing, Huang, Junjie, Huda, M Mamun, Ifeagwu, Susan C, Ikuta, Kevin S, Ilesanmi, Olayinka Stephen, Irvani, Seyed Sina Naghibi, Islam, Rakibul M, Islam, Sheikh Mohammed Shariful, Ismail, Nahlah Elkudssiah, Iso, Hiroyasu, Isola, Gaetano, Itumalla, Ramaiah, Iwagami, Masao, Jahani, Mohammad Ali, Jahanmehr, Nader, Jain, Rajesh, Jakovljevic, Mihajlo, Janodia, Manthan Dilipkumar, Jayapal, Sathish Kumar, Jayaram, Shubha, Jha, Ravi Prakash, Jonas, Jost B, Joo, Tama, Joseph, Nitin, Jürisson, Mikk, Kabir, Ali, Kalankesh, Leila R, Kalhor, Rohollah, Kamath, Aruna M, Kamenov, Kaloyan, Kandel, Himal, Kantar, Rami S, Kapoor, Neeti, Karanikolos, Marina, Katikireddi, Srinivasa Vittal, Kavetskyy, Tara, Kawakami, Norito, Kayode, Gbenga A, Keikavoosi-Arani, Leila, Keykhaei, Mohammad, Khader, Yousef Saleh, Khajuria, Himanshu, Khalilov, Rovshan, Khammarnia, Mohammad, Khan, Md Nuruzzaman, Khan, Moien AB, Khan, Maseer, Khezeli, Mehdi, Kim, Min Seo, Kim, Yun Jin, Kisa, Sezer, Kisa, Adnan, Klymchuk, Vitalii, Koly, Kamrun Nahar, Korzh, Oleksii, Kosen, Soewarta, Koul, Parvaiz A, Kuate Defo, Barthelemy, Kumar, G Anil, Kusuma, Dian, Kyu, Hmwe Hmwe, Larsson, Anders O, Lasrado, Savita, Lee, Wei-Chen, Lee, Yo Han, Lee, Chiachi Bonnie, Li, Shanshan, Lucchetti, Giancarlo, Mahajan, Preetam Bhalchandra, Majeed, Azeem, Makki, Alaa, Malekzadeh, Reza, Malik, Ahmad Azam, Malta, Deborah Carvalho, Mansournia, Mohammad Ali, Mantovani, Lorenzo Giovanni, Martinez-Valle, Adolfo, Martins-Melo, Francisco Rogerlândio, Masoumi, Seyedeh Zahra, Mathur, Manu Raj, Maude, Richard Jame, Maulik, Pallab K, 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Adrian, Padubidri, Jagadish Rao, Palladino, Raffaele, Pana, Adrian, Panda-Jonas, Songhomitra, Pandi-Perumal, Seithikurippu R, Pardhan, Shahina, Pasupula, Deepak Kumar, Pathak, Praveen Kumar, Patton, George C, Pawar, Shrikant, Pereira, Jeevan, Pilania, Manju, Piroozi, Bakhtiar, Podder, Vivek, Pokhrel, Khem Narayan, Postma, Maarten J, Prada, Sergio I, Quazi Syed, Zahiruddin, Rabiee, Navid, Radhakrishnan, Raghu Anekal, Rahman, Md Mosfequr, Rahman, Mosiur, Rahman, Mahfuzar, Rahman, Mohammad Hifz Ur, Rahmani, Amir Masoud, Ranabhat, Chhabi Lal, Rao, Chythra R, Rao, Sowmya J, Rasella, Davide, Rawaf, Salman, Rawaf, David Laith, Rawal, Lal, Renzaho, Andre M N, Reshmi, Bhageerathy, Resnikoff, Serge, Rezapour, Aziz, Riahi, Seyed Mohammad, Ripon, Rezaul Karim, Sacco, Simona, Sadeghi, Masoumeh, Saeed, Umar, Sahebkar, Amirhossein, Sahiledengle, Biniyam, Sahoo, Harihar, Sahu, Maitreyi, Salama, Joseph S, Salamati, Payman, Samy, Abdallah M, Sanabria, Juan, Santric-Milicevic, Milena M, Sathian, Brijesh, Sawhney, Monika, Schmidt, Maria Inê, Seidu, Abdul-Aziz, Sepanlou, Sadaf G, Seylani, Allen, Shaikh, Masood Ali, Sheikh, Aziz, Shetty, Adithi, Shigematsu, Mika, Shiri, Rahman, Shivakumar, K M, Shokri, Azad, Singh, Jasvinder A, Sinha, Dhirendra Narain, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Sofi-Mahmudi, Ahmad, Sousa, Raúl A R C, Stephens, Jacqueline H, Sun, Jing, Szócska, Mikló, Tabarés-Seisdedos, Rafael, Tadbiri, Hooman, Tamiru, Animut Tagele, Thankappan, Kavumpurathu Raman, Topor-Madry, Roman, Tovani-Palone, Marcos Roberto, Tran, Mai Thi Ngoc, Tran, Bach Xuan, Tripathi, Niharika, Tripathy, Jaya Prasad, Troeger, Christopher E, Uezono, Deinzel Roble, Ullah, Saif, Ullah, Anayat, Unnikrishnan, Bhaskaran, Vacante, Marco, Valadan Tahbaz, Sahel, Valdez, Pascual R, Vasic, Milena, Veroux, Massimiliano, Vervoort, Dominique, Violante, Francesco S, Vladimirov, Sergey Konstantinovitch, Vlassov, Vasily, Vo, Bay, Waheed, Yasir, Wamai, Richard G, Wang, Yuan-Pang, Wang, Yanzhong, Ward, Paul, Wiangkham, Taweewat, Yadav, Lalit, Yahyazadeh Jabbari, Seyed Hossein, Yamagishi, Kazumasa, Yaya, Sanni, Yazdi-Feyzabadi, Vahid, Yi, Siyan, Yiğit, Vahit, Yonemoto, Naohiro, Younis, Mustafa Z, Yu, Chuanhua, Yunusa, Ismaeel, Zaman, Sojib Bin, Zastrozhin, Mikhail Sergeevich, Zhang, Zhi-Jiang, Zhong, Chenwen, Zuniga, Yves Miel H, Lim, Stephen S, Murray, Christopher J L, Lozano, Rafael, Haakenstad, A, Yearwood, J, Fullman, N, Bintz, C, Bienhoff, K, Weaver, M, Nandakumar, V, Joffe, J, Legrand, K, Knight, M, Abbafati, C, Abbasi-Kangevari, M, Abdoli, A, Abeldano Zuniga, R, Adedeji, I, Adekanmbi, V, Adetokunboh, O, Afzal, M, Afzal, S, Agudelo-Botero, M, Ahinkorah, B, Ahmad, S, Ahmadi, A, Ahmadi, S, Ahmed, A, Ahmed Rashid, T, Aji, B, Akande-Sholabi, W, Alam, K, Al Hamad, H, Alhassan, R, Ali, L, Alipour, V, Aljunid, S, Ameyaw, E, Amin, T, Amu, H, Amugsi, D, Ancuceanu, R, Andrade, P, Anjum, A, Arabloo, J, Arab-Zozani, M, Ariffin, H, Arulappan, J, Aryan, Z, Ashraf, T, Atnafu, D, Atreya, A, Ausloos, M, Avila-Burgos, L, Ayano, G, Ayanore, M, Azari, S, Badiye, A, Baig, A, Bairwa, M, Bakkannavar, S, Baliga, S, Banik, P, Barnighausen, T, Barra, F, Barrow, A, Basu, S, Bayati, M, Belete, R, Bell, A, Bhagat, D, Bhagavathula, A, Bhardwaj, P, Bhardwaj, N, Bhaskar, S, Bhattacharyya, K, Bhutta, Z, Bibi, S, Bijani, A, Bikbov, B, Biondi, A, Bolarinwa, O, Bonny, A, Brenner, H, Buonsenso, D, Burkart, K, Busse, R, Butt, Z, Butt, N, Caetano dos Santos, F, Cahuana-Hurtado, L, Camera, L, Cardenas, R, Carneiro, V, Catala-Lopez, F, Chandan, J, Charan, J, Chavan, P, Chen, S, Choudhari, S, Chowdhury, E, Chowdhury, M, Cirillo, M, Corso, B, Dadras, O, Dahlawi, S, Dai, X, Dandona, L, Dandona, R, Dangel, W, Davila-Cervantes, C, Davletov, K, Deuba, K, Dhimal, M, Djalalinia, S, Do, H, Doshmangir, L, Duncan, B, Effiong, A, Ehsani-Chimeh, E, Elgendy, I, Elhadi, M, El Sayed, I, El Tantawi, M, Erku, D, Eskandarieh, S, Fares, J, Farzadfar, F, Ferrero, S, Ferro Desideri, L, Fischer, F, Foigt, N, Foroutan, M, Fukumoto, T, Gaal, P, Gaihre, S, Gardner, W, Garg, T, Getachew Obsa, A, Ghafourifard, M, Ghashghaee, A, Ghith, N, Gilani, S, Gill, P, Goharinezhad, S, Golechha, M, Guadamuz, J, Guo, Y, Gupta, R, Gupta, V, Hamiduzzaman, M, Hanif, A, Haro, J, Hasaballah, A, Hasan, M, Hashi, A, Hay, S, Hayat, K, Heidari, M, Heidari, G, Henry, N, Herteliu, C, Holla, R, Hossain, S, Hossain, M, Hosseinzadeh, M, Hostiuc, S, Hoveidamanesh, S, Hsieh, V, Hu, G, Huang, J, Huda, M, Ifeagwu, S, Ikuta, K, Ilesanmi, O, Irvani, S, Islam, R, Islam, S, Ismail, N, Iso, H, Isola, G, Itumalla, R, Iwagami, M, Jahani, M, Jahanmehr, N, Jain, R, Jakovljevic, M, Janodia, M, Jayapal, S, Jayaram, S, Jha, R, Jonas, J, Joo, T, Joseph, N, Jurisson, M, Kabir, A, Kalankesh, L, Kalhor, R, Kamath, A, Kamenov, K, Kandel, H, Kantar, R, Kapoor, N, Karanikolos, M, Katikireddi, S, Kavetskyy, T, Kawakami, N, Kayode, G, Keikavoosi-Arani, L, Keykhaei, M, Khader, Y, Khajuria, H, Khalilov, R, Khammarnia, M, Khan, M, Khezeli, M, Kim, M, Kim, Y, Kisa, S, Kisa, A, Klymchuk, V, Koly, K, Korzh, O, Kosen, S, Koul, P, Kuate Defo, B, Kumar, G, Kusuma, D, Kyu, H, Larsson, A, Lasrado, S, Lee, W, Lee, Y, Lee, C, Li, S, Lucchetti, G, Mahajan, P, Majeed, A, Makki, A, Malekzadeh, R, Malik, A, Malta, D, Mansournia, M, Mantovani, L, Martinez-Valle, A, Martins-Melo, F, Masoumi, S, Mathur, M, Maude, R, Maulik, P, Mckee, M, Mendoza, W, Menezes, R, Mensah, G, Meretoja, A, Meretoja, T, Mestrovic, T, Michalek, I, Mirrakhimov, E, Misganaw, A, Misra, S, Moazen, B, Mohammadi, M, Mohammed, S, Moitra, M, Mokdad, A, Molokhia, M, Monasta, L, Moni, M, Moradi, G, Moreira, R, Mosser, J, Mostafavi, E, Mouodi, S, Nagarajan, A, Nagata, C, Naghavi, M, Nangia, V, Narasimha Swamy, S, Narayana, A, Nascimento, B, Nassereldine, H, Nayak, B, Nazari, J, Negoi, I, Nepal, S, Neupane Kandel, S, Ngunjiri, J, Nguyen, H, Nguyen, C, Ningrum, D, Noubiap, J, Oancea, B, Oghenetega, O, Oh, I, Olagunju, A, Olakunde, B, Omar Bali, A, Omer, E, Onwujekwe, O, Otoiu, A, Padubidri, J, Palladino, R, Pana, A, Panda-Jonas, S, Pandi-Perumal, S, Pardhan, S, Pasupula, D, Pathak, P, Patton, G, Pawar, S, Pereira, J, Pilania, M, Piroozi, B, Podder, V, Pokhrel, K, Postma, M, Prada, S, Quazi Syed, Z, Rabiee, N, Radhakrishnan, R, Rahman, M, Rahmani, A, Ranabhat, C, Rao, C, Rao, S, Rasella, D, Rawaf, S, Rawaf, D, Rawal, L, Renzaho, A, Reshmi, B, Resnikoff, S, Rezapour, A, Riahi, S, Ripon, R, Sacco, S, Sadeghi, M, Saeed, U, Sahebkar, A, Sahiledengle, B, Sahoo, H, Sahu, M, Salama, J, Salamati, P, Samy, A, Sanabria, J, Santric-Milicevic, M, Sathian, B, Sawhney, M, Schmidt, M, Seidu, A, Sepanlou, S, Seylani, A, Shaikh, M, Sheikh, A, Shetty, A, Shigematsu, M, Shiri, R, Shivakumar, K, Shokri, A, Singh, J, Sinha, D, Skryabin, V, Skryabina, A, Sofi-Mahmudi, A, Sousa, R, Stephens, J, Sun, J, Szocska, M, Tabares-Seisdedos, R, Tadbiri, H, Tamiru, A, Thankappan, K, Topor-Madry, R, Tovani-Palone, M, Tran, M, Tran, B, Tripathi, N, Tripathy, J, Troeger, C, Uezono, D, Ullah, S, Ullah, A, Unnikrishnan, B, Vacante, M, Valadan Tahbaz, S, Valdez, P, Vasic, M, Veroux, M, Vervoort, D, Violante, F, Vladimirov, S, Vlassov, V, Vo, B, Waheed, Y, Wamai, R, Wang, Y, Ward, P, Wiangkham, T, Yadav, L, Yahyazadeh Jabbari, S, Yamagishi, K, Yaya, S, Yazdi-Feyzabadi, V, Yi, S, Yigit, V, Yonemoto, N, Younis, M, Yu, C, Yunusa, I, Zaman, S, Zastrozhin, M, Zhang, Z, Zhong, C, Zuniga, Y, Lim, S, Murray, C, Lozano, R, Bill & Melinda Gates Foundation, King Edward Medical University (Pakistán), Kuwait University (Kuwait), Romanian National Authority for Scientific Research and Innovation, Romanian Ministry of Research Innovation and Digitalization, Alexander von Humboldt Foundation, Federal Ministry of Education & Research (Alemania), Unión Europea. Comisión Europea. H2020, University of Aberdeen (Reino Unido), Novo Nordisk Foundation, National Health and Medical Research Council (Australia), National Research, Development and Innovation Office (Hungria), National Records of Scotland (Reino Unido), Medical Research Council (Reino Unido), Scottish Government (Reino Unido), Jatiya Kabi Kazi Nazrul Islam University (Bangladesh), Xiamen University Malaysia (Malasia), National Council for Scientific and Technological Development (Brasil), Ministero della Salute (Italia), Fondazione IRCCS. Istituto Nazionale dei Tumori, King College London, IRCCS Materno Infantile Burlo Garofolo (Italia), Edwards Lifesciences Foundation, Fundação de Amparo à Pesquisa do Estado de Minas Gerais (Brasil), Manipal Academy of Higher Education (India), Ministerio de Ciencia e Innovación. Centro de Excelencia Severo Ochoa (España), Government of Catalonia (España), International Center of Medical Sciences Research (Pakistán), Ain Shams University (Egipto), Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red - CIBERSAM (Salud Mental), INCLIVA Health Research Institute (España), Canadian Institutes of Health Research, Australian Government, and Ministry of Education, Science and Technological Development (Serbia)
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Adult ,Adolescent ,Population ,Global Health ,Health Services Accessibility ,Global Burden of Disease ,Health system quality ,Young Adult ,Nations ,Health systems ,health care access ,Risk Factors ,Quality-Adjusted Life Year ,Humans ,Child ,Global Burden of Disease Study 2019 ,Health-care access ,Aged ,Quality of Health Care ,quality ,performance ,The Healthcare Access and Quality Index ,Risk Factor ,Infant, Newborn ,Infant ,eu-repo/semantics/review [info] ,Public Health, Global Health, Social Medicine and Epidemiology ,General Medicine ,Health-care quality ,Middle Aged ,3141 Health care science ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Indicator ,Medical-care ,Child, Preschool ,Deaths ,Amenable mortality ,Quality-Adjusted Life Years ,Age groups ,Trends ,Human - Abstract
Background: Health-care needs change throughout the life course. It is thus crucial to assess whether health systems provide access to quality health care for all ages. Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019), we measured the Healthcare Access and Quality (HAQ) Index overall and for select age groups in 204 locations from 1990 to 2019. Methods: We distinguished the overall HAQ Index (ages 0-74 years) from scores for select age groups: the young (ages 0-14 years), working (ages 15-64 years), and post-working (ages 65-74 years) groups. For GBD 2019, HAQ Index construction methods were updated to use the arithmetic mean of scaled mortality-to-incidence ratios (MIRs) and risk-standardised death rates (RSDRs) for 32 causes of death that should not occur in the presence of timely, quality health care. Across locations and years, MIRs and RSDRs were scaled from 0 (worst) to 100 (best) separately, putting the HAQ Index on a different relative scale for each age group. We estimated absolute convergence for each group on the basis of whether the HAQ Index grew faster in absolute terms between 1990 and 2019 in countries with lower 1990 HAQ Index scores than countries with higher 1990 HAQ Index scores and by Socio-demographic Index (SDI) quintile. SDI is a summary metric of overall development. Findings: Between 1990 and 2019, the HAQ Index increased overall (by 19·6 points, 95% uncertainty interval 17·9-21·3), as well as among the young (22·5, 19·9-24·7), working (17·2, 15·2-19·1), and post-working (15·1, 13·2-17·0) age groups. Large differences in HAQ Index scores were present across SDI levels in 2019, with the overall index ranging from 30·7 (28·6-33·0) on average in low-SDI countries to 83·4 (82·4-84·3) on average in high-SDI countries. Similarly large ranges between low-SDI and high-SDI countries, respectively, were estimated in the HAQ Index for the young (40·4-89·0), working (33·8-82·8), and post-working (30·4-79·1) groups. Absolute convergence in HAQ Index was estimated in the young group only. In contrast, divergence was estimated among the working and post-working groups, driven by slow progress in low-SDI countries. Interpretation: Although major gaps remain across levels of social and economic development, convergence in the young group is an encouraging sign of reduced disparities in health-care access and quality. However, divergence in the working and post-working groups indicates that health-care access and quality is lagging at lower levels of social and economic development. To meet the needs of ageing populations, health systems need to improve health-care access and quality for working-age adults and older populations while continuing to realise gains among the young. O Adetokunboh acknowledges support from Department of Science and Innovation and National Research Foundation. S Afzal acknowledges the institutional support of King Edward Medical University. S Aljunid acknowledges Department of Health Policy and Management, College of Public Health, Health Science Centre, Kuwait University for the approval and support to participate in this research project. M Ausloos, C Herteliu, and A Pana acknowledge partial support by a grant of the Romanian National Authority for Scientific Research and Innovation, CNDS-UEFISCDI, project number PN-III-P4-ID-PCCF-2016-0084. C Herteliu also acknowledges partial support by a grant of the Romanian Ministry of Research Innovation and Digitalization, MCID, project number ID-585-CTR-42-PFE-2021. T Bärnighausen was supported by the Alexander von Humboldt Foundation through the Alexander von Humboldt Professor award, funded by the Federal Ministry of Education and Research. B Bikbov acknowledges funding from the European Union’s Horizon 2020 research and innovation programme under Marie Sklodowska-Curie grant agreement No. 703226. Institute of Applied Health Sciences; School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Scotland. The salary for N Ghith is covered by a grant from Novo Nordisk Foundation (NNF16OC0021856). V B Gupta acknowledges funding support from National Health and Medical Research Council (NHMRC) Australia. V K Gupta acknowledges funding support from National Health and Medical Research Council (NHMRC) Australia. T Joo acknowledges support from the National Research, Development and Innovation Office of Hungary under grant RRF-2.3.1-21-2022-00006 (Data-driven Health Division of Health Security National Laboratory). S Vittal Katikireddi acknowledges funding from a NRS Senior Clinical Fellowship (SCAF/15/02), the Medical Research Council (MC_UU_00022/2), and the Scottish Government Chief Scientist Office (SPHSU17). M N Khan acknowledges the support of Jatiya Kabi Kazi Nazrul Islam University, Mymensingh, Bangladesh. Y J Kim acknowledges support from the Research Management Centre Xiamen University Malaysia [XMUMRF/2020-C6/ITCM/0004]. G Lucchetti is a grantee of the Brazilian National Council for Scientific and Technological Development Research Productivity - Level 1D. L Mantovani acknowledges support by Italian Ministry of Health Ricerca Corrente - IRCCS Multimedica. M Molokhia acknowledges support by the National Institute for Health Research Biomedical Research Center at Guy’s and St Thomas’ National Health Service Foundation Trust and King’s College London. L Monasta reports support for the present manuscript from the Italian Ministry of Health on project Ricerca Corrente 34/2017 and payments made to the Institute for Maternal and Child Health IRCCS Burlo Garofolo. R Moreira acknowledges the CNPQ productivity grant (316607/2021-5). B R Nascimento is partially supported by CNPq (Research Productivity Grant, 312382/2019-7), the Edwards Lifesciences Foundation (Improving the prevention and detection of Heart Valve disease across the Lifespan, 2021), and FAPEMIG (grant APQ-000627-20). J R Padubidri acknowledges Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, India for their constant support in conducting research. D Rasella reports financial support from the Spanish Ministry of Science and Innovation and State Research Agency through the Centro de Excelencia Severo Ochoa 2019-2023 programme (CEX2018-000806-S), and financial support from the Generalitat de Catalunya through the Centres de Recerca de Catalunya programme. U Saeed would like to acknowledge the International Center of Medical Sciences Research (ICMSR), Islamabad (44000), Pakistan. A M Samy acknowledges the support from Ain Shams University and the Egyptian Fulbright Mission Program. U Saeed would like to acknowledge Kasturba Medical College, Mangalore. Manipal Academy of Higher Education, Manipal for supporting research activities. R T-S is supported by the Spanish Ministry of Science and Innovation, Institute of Health Carlos III, CIBERSAM, INCLIVA (PID2021-129099OB-I00). D Vervoort is supported by the Canadian Institutes of Health Research (CIHR) Vanier Canada Graduate Scholarship. S B Zaman acknowledges receiving a scholarship from the Australian Government Research Training Program (RTP) in support of his academic career. Serbian part of this GBD contribution was co-financed through Grant OI 175 014 of the Ministry of Education Science and Technological Development of The Republic of Serbia. This work was supported, in whole or in part, by the Bill & Melinda Gates Foundation OPP1152504. Under the grant conditions of the Foundation, a Creative Commons Attribution 4.0 Generic License has already been assigned to the Author Accepted Manuscript version that might arise from this submission. Sí
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31. Modelling the impact of extended vaccination strategies on the epidemiology of pertussis
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ROZENBAUM, M. H., De VRIES, R., LE, H. H., and POSTMA, M. J.
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32. The notion of Surrogacy in Health Technology Assessment: an insight in the processes of Germany, UK and France
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Petrou, Panagiotis, primary, Pitsillidou, Olga, additional, and Postma, M. J., additional
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33. Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019
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Paulson, K. R., Kamath, A. M., Alam, T., Bienhoff, K., Abady, G. G., Abbas, J., Abbasi-Kangevari, M., Abbastabar, H., Abd-Allah, F., Abd-Elsalam, S. M., Abdoli, A., Abedi, A., Abolhassani, H., Abreu, L. G., Abu-Gharbieh, E., Abu-Rmeileh, N. M. E., Abushouk, A. I., Adamu, A. L., Adebayo, O. M., Adegbosin, A. E., Adekanmbi, V., Adetokunboh, O. O., Adeyinka, D. A., Adsuar, J. C., Afshari, K., Aghaali, M., Agudelo-Botero, M., Ahinkorah, B. O., Ahmad, T., Ahmadi, K., Ahmed, M. B., Aji, B., Akalu, Y., Akinyemi, O. O., Aklilu, A., Al-Aly, Z., Alam, K., Alanezi, F. M., Alanzi, T. M., Alcalde-Rabanal, J. E., Al-Eyadhy, A., Ali, T., Alicandro, G., Alif, S. M., Alipour, V., Alizade, H., Aljunid, S. M., Almasi-Hashiani, A., Almasri, N. A., Al-Mekhlafi, H. M., Alonso, J., Al-Raddadi, R. M., Altirkawi, K. A., Alumran, A. K., Alvis-Guzman, N., Alvis-Zakzuk, N. J., Ameyaw, E. K., Amini, S., Amini-Rarani, M., Amit, A. M. L., Amugsi, D. A., Ancuceanu, R., Anderlini, D., Andrei, C. L., Ansari, F., Ansari-Moghaddam, A., Antonio, C. A. T., Antriyandarti, E., Anvari, D., Anwer, R., Aqeel, M., Arabloo, J., Arab-Zozani, M., Aripov, T., Arnlov, J., Artanti, K. D., Arzani, A., Asaad, M., Asadi-Aliabadi, M., Asadi-Pooya, Ali A, Jafarabadi, M. A., Athari, S. S., Athari, S. M., Atnafu, D. D., Atreya, A., Atteraya, M. S., Ausloos, M., Awan, A. T., Quintanilla, B. P. A., Ayano, G., Ayanore, M. A., Aynalem, Y. A., Azari, S., Azarian, G., Azene, Z. N., Darshan, BB, Babaee, E., Badiye, A. D., Baig, A. A., Banach, M., Banik, P. C., Barker-Collo, S. L., Barqawi, H. J., Bassat, Q., Basu, S., Baune, B.T., Bayati, M., Bedi, N., Beghi, E., Beghi, M., Bell, M. L., Bendak, S., Bennett, D. A., Bensenor, I. M., Berhe, K., Berman, A. E., Bezabih, Y. M., Bhagavathula, A. S., Bhandari, D., Bhardwaj, N., Bhardwaj, P., Bhattacharyya, K., Bhattarai, S., Bhutta, Z. A., Bikbov, B., Biondi, A., Birihane, B. M., Biswas, R. K., Bohlouli, S., Bragazzi, N. L., Breusov, A. V., Brunoni, A. R., Burkart, K., Nagaraja, S. B., Busse, R., Butt, Z. A., dos Santos, F. L. C., Cahuana-Hurtado, L., Camargos, P., Camera, L. A., Cardenas, R., Carreras, G., Carrero, J. J., Carvalho, F., Castaldelli-Maia, J. M., Castaneda-Orjuela, C. A., Castelpietra, G., Cerin, E., Chang, J-C., Chanie, W. F., Charan, J., Chatterjee, S., Chattu, S. K., Chattu, V. K., Chaturvedi, S., Chen, S., Cho, D. Y., Choi, J-Y. J., Chu, D-T., Ciobanu, L. G., Cirillo, M., Conde, J., Costa, V. M., Couto, R. A. S., Dachew, B. A., Dahlawi, S. M. A., Dai, H., Dai, X., Dandona, L., Dandona, R., Daneshpajouhnejad, P., Darmstadt, G. L., Das, J. K., Davila-Cervantes, C. A., Davis, A. C., Davletov, K., De la Hoz, F. P., De Leo, D., Deeba, F., Denova-Gutierrez, E., Dervenis, N., Desalew, A., Deuba, K., Dey, S., Dharmaratne, S. D., Dhingra, S., Dhungana, G. P., da Silva, D. D., Diaz, D., Dorostkar, F., Doshmangir, L., Dubljanin, E., Duraes, A. R., Eagan, A. W., Edinur, H. A., Efendi, F., Eftekharzadeh, S., El Sayed, I., El Tantawi, M., Elbarazi, I., Elgendy, I. Y., El-Jaafary, S. I., Emami, A., Enany, S., Eyawo, O., Ezzikouri, S., Faris, P. S., Farzadfar, F., Fattahi, N., Fauk, N. K., Fazlzadeh, M., Feigin, V. L., Ferede, T. Y., Fereshtehnejad, S-M., Fernandes, E., Ferrara, P., Filip, I., Fischer, F., Fisher, J. L., Foigt, N. A., Folayan, M. O., Foroutan, M., Franklin, R. C., Freitas, M., Friedman, S. D., Fukumoto, T., Gad, M. M., Gaidhane, A. M., Gaidhane, S., Gaihre, S., Gallus, S., Garcia-Basteiro, A. L., Garcia-Gordillo, M., Gardner, W. M., Fonseca, M. G., Gebremedhin, K. B., Getacher, L., Ghashghaee, A., Gholamian, A., Gilani, S.A., Gill, T. K., Giussani, G., Gnedovskaya, E. V., Godinho, M. A., Goel, A., Golechha, M., Gona, P. N., Gopalani, S. V., Goudarzi, H., Grivna, M., Gugnani, H. C., Guido, D., Guimaraes, R. A., Das Gupta, R., Gupta, R., Hafezi-Nejad, N., Haider, M. R., Haj-Mirzaian, A., Hamidi, S., Hanif, A., Hankey, G. J., Hargono, A., Hasaballah, A. I., Hasan, M. M., Hasan, S. S., Hassan, A., Hassanipour, S., Hassankhani, H., Havmoeller, R. J., Hayat, K., Heidari-Soureshjani, R., Henry, N. J., Herteliu, C., Hole, M. K., Holla, R., Hossain, N., Hosseini, M., Hosseinzadeh, M., Hostiuc, M., Hostiuc, S., Househ, M., Huang, J., Humayun, A., Hwang, B-F., Iavicoli, I., Ibitoye, S. E., Ikuta, K. S., Ilesanmi, O. St., Ilic, I.M., Ilic, M. D., Inamdar, S., Inbaraj, L. R., Iqbal, K., Iqbal, U., Islam, M. M., Islam, S. M. S., Iso, H., Iwagami, M., Iwu, C. C. D., Jaafari, J., Jacobsen, K. H., Jagnoor, J., Jain, V., Janodia, M. D., Javaheri, T., Javanmardi, F., Jayaram, S., Jayatilleke, A. U., Jenabi, E., Jha, R. P., Ji, J. S., John, O., Jonas, J. B., Joo, T., Joseph, N., Joukar, F., Jozwiak, J.J., Jurisson, M., Kabir, A., Kabir, Z., Kalankesh, L. R., Kamyari, N., Kanchan, T., Kapoor, N., Matin, B. K., Karch, A., Karimi, S. E., Kassahun, G., Kayode, G. A., Karyani, A. K., Kemmer, L., Khalid, N., Khalilov, R., Khammarnia, M., Khan, E. A., Khan, G., Khan, M., Khan, M. N., Khang, Y-H., Khatab, K., Khater, A. M., Khater, M. M., Khayamzadeh, M., Khosravi, A., Kim, D., Kim, Y-E., Kim, Y. J., Kimokoti, R. W., Kisa, A., Kisa, S., Kissoon, N., Kopec, J. A., Kosen, S., Koul, P. A., Laxminarayana, S. L. K., Koyanagi, A., Krishan, K., Krishnamoorthy, V., Defo, B. K., Bicer, B. K., Kulkarni, V., Kumar, G. A., Kumar, M., Kumar, N., Kurmi, O. P., Kusuma, D., La Vecchia, C., Lacey, B., Lalloo, R., Lami, F.H., Landires, I., Larsson, A. O., Lasrado, S., Lassi, Z. S., Lauriola, P., Lee, P. H., Lee, S. W. H., Lee, Y. H., Leigh, J., Leonardi, M., Lewycka, S., Li, B., Li, S., Liang, J., Lim, L-L., Limenih, M. A., Lin, R-T., Liu, X., Lodha, R., Lopez, A. D., Lozano, R., Lugo, A., Lunevicius, R., Mackay, M. T., Kunjathur, S. M., Magnani, F. G., Prasad, D. R. M., Maheri, M., Mahmoudi, M., Majeed, A., Maled, V., Maleki, A., Maleki, S., Malekzadeh, R., Malik, A. A., Malta, D. C., Mamun, A. A., Mansouri, B., Mansournia, M. A., Martinez, G., Martini, S., Martins-Melo, F. R., Masoumi, S. Z., Maulik, P. K., McAlinden, C., McGrath, J. J., Medina-Solis, C. E., Nasab, E. M., Mejia-Rodriguez, F., Memish, Z.A., Mendoza, W., Menezes, R. G., Mengesha, E. W., Mensah, G. A., Meretoja, A., Meretoja, T. J., Mersha, A. M., Mestrovic, T., Miazgowski, B., Miazgowski, T., Michalek, I. M., Miller, T.R., Mini, G. K., Miri, M., Mirica, A., Mirrakhimov, .E M., Mirzaei, H., Mirzaei, M., Moazen, B., Moghadaszadeh, M., Mohajer, B., Mohamad, O., Mohammad, Y., Mohammadi, S. M., Mohammadian-Hafshejani, A., Mohammed, S., Mokdad, A. H., Molokhia, M., Monasta, L., Mondello, S., Moni, M. A., Moore, C. E., Moradi, G., Moradi, M., Moradzadeh, R., Moraga, P., Morawska, L., Morrison, S. D., Mosser, J. F., Khaneghah, A. M., Mustafa, G., Naderi, M., Nagarajan, A. J., Nagaraju, S. P., Naghavi, M., Naghshtabrizi, B., Naimzada, M. D., Nangia, V., Swamy, S. N., Nascimento, B. R., Naveed, M., Nazari, J., Ndejjo, R., Negoi, I., Negoi, R. I., Nena, E., Nepal, S., Netsere, H. B., Nguefack-Tsague, G., Ngunjiri, J. W., Nguyen, C. T. Y., Nguyen, C. T., Nguyen, H. L. T., Nigatu, Y. T., Nigussie, S. N., Nixon, M. R., Nnaji, C. A., Nomura, S., Noor, N. M., Noubiap, J. J., Nunez-Samudio, V., Nwatah, V. E., Oancea, B., Odukoya, O. O., Ogbo, F. A., Olusanya, B. O., Olusanya, J. O., Bali, A. O., Onwujekwe, O. E., Ortiz, A., Otoiu, A., Otstavnov, N., Otstavnov, S. S., Owolabi, M. O., Mahesh, P. A., Padubidri, J. R., Pakhale, S., Pakshir, K., Pal, P. K., Palladino, R., Pana, A., Panda-Jonas, S., Pandey, A., Pandi-Perumal, S. R., Pangaribuan, H. U., Pardo-Montano, A. M., Park, E-K., Patel, S. K., Patton, G. C., Pawar, S., Toroudi, H. P., Peden, A. E., Pepito, V. C. F., Peprah, E. K., Pereira, J., Perez-Gomez, J., Perico, N., Pesudovs, K., Pilgrim, T., Pinheiro, M., Piradov, M. A., Pirsaheb, M., Platts-Mills, J. A., Pokhrel, K. N., Postma, M. J., Pourjafar, H., Prada, S. I., Prakash, S., Pupillo, E., Syed, Z. Q., Rabiee, N., Radfar, A., Rafiee, A., Rafiei, A., Raggi, A., Rahimzadeh, S., Rahman, M. H. U., Rahmani, A. M., Ramezanzadeh, K., Rana, J., Ranabhat, C. L., Rao, S. J., Rasella, D., Rastogi, P., Rathi, P., Rawaf, D. L., Rawaf, S., Rawasia, W. F., Rawassizadeh, R., Jr, R. C. R., Remuzzi, G., Renzaho, A. M. N., Reshmi, B., Resnikoff, S., Rezaei, N., Rezapour, A., Riahi, S. M., Ribeiro, D., Rickard, J., Roever, L., Ronfani, L., Rothenbacher, D., Rubagotti, E., Rumisha, S. F., Ryan, P. M., Saddik, B., Sadeghi, E., Moghaddam, S. S., Sagar, R., Sahebkar, A., Salahshoor, M. R., Salehi, S., Salem, M. R., Salimzadeh, H., Salomon, J. A., Samodra, Y. L., Samy, A. M., Sanabria, J., Santric-Milicevic, M. M., Saraswathy, S. Y. I., Sarker, A.R., Sarrafzadegan, N., Sarveazad, A., Sathian, B., Sathish, T., Sattin, D., Saxena, S., Saya, G. K., Saylan, M., Schiavolin, S., Schlaich, M. P., Schwebel, D. C., Schwendicke, F., Senthilkumaran, S., Sepanlou, S. G., Servan-Mori, E., Sha, F., Shafaat, O., Shahabi, S., Shahbaz, M., Shaheen, A. A., Shahid, I., Shaikh, M. A., Shakiba, S., Shalash, A. S., Shams-Beyranvand, M., Shannawaz, M., Sharafi, K., Sheikh, A., Sheikhbahaei, S., Shiferaw, W. S., Shigematsu, M., Shin, J. I. l., Shiri, R., Shiue, I., Shuval, K., Siddiqi, T. J., Sidemo, N. B., Sigfusdottir, I. D., Sigurvinsdottir, R., Silva, J. P., Silverberg, J. I. S., Simonetti, B., Singh, B.B., Singh, J. A., Singhal, D., Sinha, D. N., Skiadaresi, E., Skryabin, V. Y., Skryabina, A. A., Sleet, D. A., Sobaih, B. H., Sobhiyeh, M. R., Soltani, S., Soriano, J. B., Spurlock, E. E., Sreeramareddy, C. T., Steiropoulos, P., Stokes, M. A., Stortecky, S., Sufiyan, M. B., Abdulkader, R. S., Sulo, G., Swope, C. B., Sykes, B. L., Szeto, M. D., Szocska, M., Tabares-Seisdedos, R., Tadesse, E. G., Taherkhani, A., Tamiru, A.T., Tareque, M. I., Tehrani-Banihashemi, A., Temsah, M-H., Tesfay, F. H., Tessema, G. A., Tessema, Z. T., Thankappan, K. R., Thapar, R., Tolani, M. A., Tovani-Palone, M. R., Traini, E., Tran, B. X., Tripathy, J. P., Tsapparellas, G., Tsatsakis, A., Car, L. T., Uddin, R., Ullah, A., Umeokonkwo, C. D., Unim, B., Unnikrishnan, B., Upadhyay, E., Usman, M. S., Vacante, M., Vaezi, M., Tahbaz, S. V., Valdez, P. R., Vasankari, T. J., Venketasubramanian, N., Verma, M., Violante, F. S., Vlassov, V., Vo, B., Vu, G. T., Wado, Y. D., Waheed, Y., Wamai, R. G., Wang, Y., Wang, Y-P., Ward, P., Werdecker, A., Westerman, R., Wickramasinghe, N. D., Wilner, L. B., Wiysonge, C. S., Wu, A-M., Wu, C., Xie, Y., Jabbari, S. H. Y., Yamagishi, K., Yandrapalli, S., Yaya, S., Yazdi-Feyzabadi, V., Yip, P., Yonemoto, N., Yoon, S-J., Younis, M. Z., Yousefi, Z., Yousefinezhadi, T., Yu, C., Yusuf, S. S., Zaidi, S. S., Bin Zaman, S., Zamani, M., Zamanian, M., Zastrozhin, M. S., Zastrozhina, A., Zhang, Y., Zhang, Z-J., Zhao, X-J. G., Ziapour, A., Hay, S. I., Murray, C. J. L., Wang, H., Kassebaum, N. J., GBD 2019 Under-5 Mortality Collaborators, Paulson K.R., Kamath A.M., Alam T., Bienhoff K., Abady G.G., Abbas J., Abbasi-Kangevari M., Abbastabar H., Abd-Allah F., Abd-Elsalam S.M., Abdoli A., Abedi A., Abolhassani H., Abreu L.G., Abu-Gharbieh E., Abu-Rmeileh N.M., Abushouk A.I., Adamu A.L., Adebayo O.M., Adegbosin A.E., Adekanmbi V., Adetokunboh O.O., Adeyinka D.A., Adsuar J.C., Afshari K., Aghaali M., Agudelo-Botero M., Ahinkorah B.O., Ahmad T., Ahmadi K., Ahmed M.B., Aji B., Akalu Y., Akinyemi O.O., Aklilu A., Al-Aly Z., Alam K., Alanezi F.M., Alanzi T.M., Alcalde-Rabanal J.E., Al-Eyadhy A., Ali T., Alicandro G., Alif S.M., Alipour V., Alizade H., Aljunid S.M., Almasi-Hashiani A., Almasri N.A., Al-Mekhlafi H.M., Alonso J., Al-Raddadi R.M., Altirkawi K.A., Alumran A.K., Alvis-Guzman N., Alvis-Zakzuk N.J., Ameyaw E.K., Amini S., Amini-Rarani M., Amit A.M.L., Amugsi D.A., Ancuceanu R., Anderlini D., Andrei C.L., Ansari F., Ansari-Moghaddam A., Antonio C.A.T., Antriyandarti E., Anvari D., Anwer R., Aqeel M., Arabloo J., Arab-Zozani M., Aripov T., Arnlov J., Artanti K.D., Arzani A., Asaad M., Asadi-Aliabadi M., Asadi-Pooya A.A., Asghari Jafarabadi M., Athari S.S., Athari S.M., Atnafu D.D., Atreya A., Atteraya M.S., Ausloos M., Awan A.T., Ayala Quintanilla B.P., Ayano G., Ayanore M.A., Aynalem Y.A., Azari S., Azarian G., Azene Z.N., B D.B., Babaee E., Badiye A.D., Baig A.A., Banach M., Banik P.C., Barker-Collo S.L., Barqawi H.J., Bassat Q., Basu S., Baune B.T., Bayati M., Bedi N., Beghi E., Beghi M., Bell M.L., Bendak S., Bennett D.A., Bensenor I.M., Berhe K., Berman A.E., Bezabih Y.M., Bhagavathula A.S., Bhandari D., Bhardwaj N., Bhardwaj P., Bhattacharyya K., Bhattarai S., Bhutta Z.A., Bikbov B., Biondi A., Birihane B.M., Biswas R.K., Bohlouli S., Bragazzi N.L., Breusov A.V., Brunoni A.R., Burkart K., Burugina Nagaraja S., Busse R., Butt Z.A., Caetano dos Santos F.L., Cahuana-Hurtado L., Camargos P., Camera L.A., Cardenas R., Carreras G., Carrero J.J., Carvalho F., Castaldelli-Maia J.M., Castaneda-Orjuela C.A., Castelpietra G., Cerin E., Chang J.-C., Chanie W.F., Charan J., Chatterjee S., Chattu S.K., Chattu V.K., Chaturvedi S., Chen S., Cho D.Y., Choi J.-Y.J., Chu D.-T., Ciobanu L.G., Cirillo M., Conde J., Costa V.M., Couto R.A.S., Dachew B.A., Dahlawi S.M.A., Dai H., Dai X., Dandona L., Dandona R., Daneshpajouhnejad P., Darmstadt G.L., Das J.K., Davila-Cervantes C.A., Davis A.C., Davletov K., De la Hoz F.P., De Leo D., Deeba F., Denova-Gutierrez E., Dervenis N., Desalew A., Deuba K., Dey S., Dharmaratne S.D., Dhingra S., Dhungana G.P., Dias da Silva D., Diaz D., Dorostkar F., Doshmangir L., Dubljanin E., Duraes A.R., Eagan A.W., Edinur H.A., Efendi F., Eftekharzadeh S., El Sayed I., El Tantawi M., Elbarazi I., Elgendy I.Y., El-Jaafary S.I., Emami A., Enany S., Eyawo O., Ezzikouri S., Faris P.S., Farzadfar F., Fattahi N., Fauk N.K., Fazlzadeh M., Feigin V.L., Ferede T.Y., Fereshtehnejad S.-M., Fernandes E., Ferrara P., Filip I., Fischer F., Fisher J.L., Foigt N.A., Folayan M.O., Foroutan M., Franklin R.C., Freitas M., Friedman S.D., Fukumoto T., Gad M.M., Gaidhane A.M., Gaidhane S., Gaihre S., Gallus S., Garcia-Basteiro A.L., Garcia-Gordillo M.A., Gardner W.M., Gaspar Fonseca M., Gebremedhin K.B., Getacher L., Ghashghaee A., Gholamian A., Gilani S.A., Gill T.K., Giussani G., Gnedovskaya E.V., Godinho M.A., Goel A., Golechha M., Gona P.N., Gopalani S.V., Goudarzi H., Grivna M., Gugnani H.C., Guido D., Guimaraes R.A., Gupta R.D., Gupta R., Hafezi-Nejad N., Haider M.R., Haj-Mirzaian A., Hamidi S., Hanif A., Hankey G.J., Hargono A., Hasaballah A.I., Hasan M.M., Hasan S.S., Hassan A., Hassanipour S., Hassankhani H., Havmoeller R.J., Hayat K., Heidari-Soureshjani R., Henry N.J., Herteliu C., Hole M.K., Holla R., Hossain N., Hosseini M., Hosseinzadeh M., Hostiuc M., Hostiuc S., Househ M., Huang J., Humayun A., Hwang B.-F., Iavicoli I., Ibitoye S.E., Ikuta K.S., Ilesanmi O.S., Ilic I.M., Ilic M.D., Inamdar S., Inbaraj L.R., Iqbal K., Iqbal U., Islam M.M., Islam S.M.S., Iso H., Iwagami M., Iwu C.C.D., Jaafari J., Jacobsen K.H., Jagnoor J., Jain V., Janodia M.D., Javaheri T., Javanmardi F., Jayaram S., Jayatilleke A.U., Jenabi E., Jha R.P., Ji J.S., John O., Jonas J.B., Joo T., Joseph N., Joukar F., Jozwiak J.J., Jurisson M., Kabir A., Kabir Z., Kalankesh L.R., Kamyari N., Kanchan T., Kapoor N., Karami Matin B., Karch A., Karimi S.E., Kassahun G., Kayode G.A., Kazemi Karyani A., Kemmer L., Khalid N., Khalilov R., Khammarnia M., Khan E.A., Khan G., Khan M., Khan M.N., Khang Y.-H., Khatab K., Khater A.M., Khater M.M., Khayamzadeh M., Khosravi A., Kim D., Kim Y.-E., Kim Y.J., Kimokoti R.W., Kisa A., Kisa S., Kissoon N., Kopec J.A., Kosen S., Koul P.A., Koulmane Laxminarayana S.L., Koyanagi A., Krishan K., Krishnamoorthy V., Kuate Defo B., Kucuk Bicer B., Kulkarni V., Kumar G.A., Kumar M., Kumar N., Kurmi O.P., Kusuma D., La Vecchia C., Lacey B., Lalloo R., Lami F.H., Landires I., Larsson A.O., Lasrado S., Lassi Z.S., Lauriola P., Lee P.H., Lee S.W.H., Lee Y.H., Leigh J., Leonardi M., Lewycka S., Li B., Li S., Liang J., Lim L.-L., Limenih M.A., Lin R.-T., Liu X., Lodha R., Lopez A.D., Lozano R., Lugo A., Lunevicius R., Mackay M.T., Madhava Kunjathur S., Magnani F.G., Mahadeshwara Prasad D.R., Maheri M., Mahmoudi M., Majeed A., Maled V., Maleki A., Maleki S., Malekzadeh R., Malik A.A., Malta D.C., Mamun A.A., Mansouri B., Mansournia M.A., Martinez G., Martini S., Martins-Melo F.R., Masoumi S.Z., Maulik P.K., McAlinden C., McGrath J.J., Medina-Solis C.E., Mehrabi Nasab E., Mejia-Rodriguez F., Memish Z.A., Mendoza W., Menezes R.G., Mengesha E.W., Mensah G.A., Meretoja A., Meretoja T.J., Mersha A.M., Mestrovic T., Miazgowski B., Miazgowski T., Michalek I.M., Miller T.R., Mini G.K., Miri M., Mirica A., Mirrakhimov E.M., Mirzaei H., Mirzaei M., Moazen B., Moghadaszadeh M., Mohajer B., Mohamad O., Mohammad Y., Mohammadi S.M., Mohammadian-Hafshejani A., Mohammed S., Mokdad A.H., Molokhia M., 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A., Kazemi Karyani, A., Kemmer, L., Khalid, N., Khalilov, R., Khammarnia, M., Khan, E. A., Khan, G., Khan, M., Khan, M. N., Khang, Y. -H., Khatab, K., Khater, A. M., Khater, M. M., Khayamzadeh, M., Khosravi, A., Kim, D., Kim, Y. -E., Kim, Y. J., Kimokoti, R. W., Kisa, A., Kisa, S., Kissoon, N., Kopec, J. A., Kosen, S., Koul, P. A., Koulmane Laxminarayana, S. L., Koyanagi, A., Krishan, K., Krishnamoorthy, V., Kuate Defo, B., Kucuk Bicer, B., Kulkarni, V., Kumar, G. A., Kumar, M., Kumar, N., Kurmi, O. P., Kusuma, D., La Vecchia, C., Lacey, B., Lalloo, R., Lami, F. H., Landires, I., Larsson, A. O., Lasrado, S., Lassi, Z. S., Lauriola, P., Lee, P. H., Lee, S. W. H., Lee, Y. H., Leigh, J., Leonardi, M., Lewycka, S., Li, B., Li, S., Liang, J., Lim, L. -L., Limenih, M. A., Lin, R. -T., Liu, X., Lodha, R., Lopez, A. D., Lozano, R., Lugo, A., Lunevicius, R., Mackay, M. T., Madhava Kunjathur, S., Magnani, F. G., Mahadeshwara Prasad, D. 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D., Szocska, M., Tabares-Seisdedos, R., Tadesse, E. G., Taherkhani, A., Tamiru, A. T., Tareque, M. I., Tehrani-Banihashemi, A., Temsah, M. -H., Tesfay, F. H., Tessema, G. A., Tessema, Z. T., Thankappan, K. R., Thapar, R., Tolani, M. A., Tovani-Palone, M. R., Traini, E., Tran, B. X., Tripathy, J. P., Tsapparellas, G., Tsatsakis, A., Tudor Car, L., Uddin, R., Ullah, A., Umeokonkwo, C. D., Unim, B., Unnikrishnan, B., Upadhyay, E., Usman, M. S., Vacante, M., Vaezi, M., Valadan Tahbaz, S., Valdez, P. R., Vasankari, T. J., Venketasubramanian, N., Verma, M., Violante, F. S., Vlassov, V., Vo, B., Vu, G. T., Wado, Y. D., Waheed, Y., Wamai, R. G., Wang, Y., Wang, Y. -P., Ward, P., Werdecker, A., Westerman, R., Wickramasinghe, N. D., Wilner, L. B., Wiysonge, C. S., Wu, A. -M., Wu, C., Xie, Y., Yahyazadeh Jabbari, S. H., Yamagishi, K., Yandrapalli, S., Yaya, S., Yazdi-Feyzabadi, V., Yip, P., Yonemoto, N., Yoon, S. -J., Younis, M. Z., Yousefi, Z., Yousefinezhadi, T., Yu, C., Yusuf, S. S., Zaidi, S. S., Zaman, S. B., Zamani, M., Zamanian, M., Zastrozhin, M. S., Zastrozhina, A., Zhang, Y., Zhang, Z. -J., Zhao, X. -J. G., Ziapour, A., Hay, S. I., Murray, C. J. L., Wang, H., Kassebaum, N. J., Clinicum, Neurologian yksikkö, HUS Neurocenter, HUS Comprehensive Cancer Center, University of Helsinki, Department of Oncology, Paulson, K, Kamath, A, Alam, T, Bienhoff, K, Abady, G, Abbas, J, Abbasi-Kangevari, M, Abbastabar, H, Abd-Allah, F, Abd-Elsalam, S, Abdoli, A, Abedi, A, Abolhassani, H, Abreu, L, Abu-Gharbieh, E, Abu-Rmeileh, N, Abushouk, A, Adamu, A, Adebayo, O, Adegbosin, A, Adekanmbi, V, Adetokunboh, O, Adeyinka, D, Adsuar, J, Afshari, K, Aghaali, M, Agudelo-Botero, M, Ahinkorah, B, Ahmad, T, Ahmadi, K, Ahmed, M, Aji, B, Akalu, Y, Akinyemi, O, Aklilu, A, Al-Aly, Z, Alam, K, Alanezi, F, Alanzi, T, Alcalde-Rabanal, J, Al-Eyadhy, A, Ali, T, Alicandro, G, Alif, S, Alipour, V, Alizade, H, Aljunid, S, Almasi-Hashiani, A, Almasri, N, Al-Mekhlafi, H, Alonso, J, Al-Raddadi, R, Altirkawi, K, Alumran, A, Alvis-Guzman, N, Alvis-Zakzuk, N, Ameyaw, E, Amini, S, Amini-Rarani, M, Amit, A, Amugsi, D, Ancuceanu, R, Anderlini, D, Andrei, C, Ansari, F, Ansari-Moghaddam, A, Antonio, C, Antriyandarti, E, Anvari, D, Anwer, R, Aqeel, M, Arabloo, J, Arab-Zozani, M, Aripov, T, Arnlov, J, Artanti, K, Arzani, A, Asaad, M, Asadi-Aliabadi, M, Asadi-Pooya, A, Asghari Jafarabadi, M, Athari, S, Atnafu, D, Atreya, A, Atteraya, M, Ausloos, M, Awan, A, Ayala Quintanilla, B, Ayano, G, Ayanore, M, Aynalem, Y, Azari, S, Azarian, G, Azene, Z, B, D, Babaee, E, Badiye, A, Baig, A, Banach, M, Banik, P, Barker-Collo, S, Barqawi, H, Bassat, Q, Basu, S, Baune, B, Bayati, M, Bedi, N, Beghi, E, Beghi, M, Bell, M, Bendak, S, Bennett, D, Bensenor, I, Berhe, K, Berman, A, Bezabih, Y, Bhagavathula, A, Bhandari, D, Bhardwaj, N, Bhardwaj, P, Bhattacharyya, K, Bhattarai, S, Bhutta, Z, Bikbov, B, Biondi, A, Birihane, B, Biswas, R, Bohlouli, S, Bragazzi, N, Breusov, A, Brunoni, A, Burkart, K, Burugina Nagaraja, S, Busse, R, Butt, Z, Caetano dos Santos, F, Cahuana-Hurtado, L, Camargos, P, Camera, L, Cardenas, R, Carreras, G, Carrero, J, Carvalho, F, Castaldelli-Maia, J, Castaneda-Orjuela, C, Castelpietra, G, Cerin, E, Chang, J, Chanie, W, Charan, J, Chatterjee, S, Chattu, S, Chattu, V, Chaturvedi, S, Chen, S, Cho, D, Choi, J, Chu, D, Ciobanu, L, Cirillo, M, Conde, J, Costa, V, Couto, R, Dachew, B, Dahlawi, S, Dai, H, Dai, X, Dandona, L, Dandona, R, Daneshpajouhnejad, P, Darmstadt, G, Das, J, Davila-Cervantes, C, Davis, A, Davletov, K, De la Hoz, F, De Leo, D, Deeba, F, Denova-Gutierrez, E, Dervenis, N, Desalew, A, Deuba, K, Dey, S, Dharmaratne, S, Dhingra, S, Dhungana, G, Dias da Silva, D, Diaz, D, Dorostkar, F, Doshmangir, L, Dubljanin, E, Duraes, A, Eagan, A, Edinur, H, Efendi, F, Eftekharzadeh, S, El Sayed, I, El Tantawi, M, Elbarazi, I, Elgendy, I, El-Jaafary, S, Emami, A, Enany, S, Eyawo, O, Ezzikouri, S, Faris, P, Farzadfar, F, Fattahi, N, Fauk, N, Fazlzadeh, M, Feigin, V, Ferede, T, Fereshtehnejad, S, Fernandes, E, Ferrara, P, Filip, I, Fischer, F, Fisher, J, Foigt, N, Folayan, M, Foroutan, M, Franklin, R, Freitas, M, Friedman, S, Fukumoto, T, Gad, M, Gaidhane, A, Gaidhane, S, Gaihre, S, Gallus, S, Garcia-Basteiro, A, Garcia-Gordillo, M, Gardner, W, Gaspar Fonseca, M, Gebremedhin, K, Getacher, L, Ghashghaee, A, Gholamian, A, Gilani, S, Gill, T, Giussani, G, Gnedovskaya, E, Godinho, M, Goel, A, Golechha, M, Gona, P, Gopalani, S, Goudarzi, H, Grivna, M, Gugnani, H, Guido, D, Guimaraes, R, Gupta, R, Hafezi-Nejad, N, Haider, M, Haj-Mirzaian, A, Hamidi, S, Hanif, A, Hankey, G, Hargono, A, Hasaballah, A, Hasan, M, Hasan, S, Hassan, A, Hassanipour, S, Hassankhani, H, Havmoeller, R, Hayat, K, Heidari-Soureshjani, R, Henry, N, Herteliu, C, Hole, M, Holla, R, Hossain, N, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Househ, M, Huang, J, Humayun, A, Hwang, B, Iavicoli, I, Ibitoye, S, Ikuta, K, Ilesanmi, O, Ilic, I, Ilic, M, Inamdar, S, Inbaraj, L, Iqbal, K, Iqbal, U, Islam, M, Islam, S, Iso, H, Iwagami, M, Iwu, C, Jaafari, J, Jacobsen, K, Jagnoor, J, Jain, V, Janodia, M, Javaheri, T, Javanmardi, F, Jayaram, S, Jayatilleke, A, Jenabi, E, Jha, R, Ji, J, John, O, Jonas, J, Joo, T, Joseph, N, Joukar, F, Jozwiak, J, Jurisson, M, Kabir, A, Kabir, Z, Kalankesh, L, Kamyari, N, Kanchan, T, Kapoor, N, Karami Matin, B, Karch, A, Karimi, S, Kassahun, G, Kayode, G, Kazemi Karyani, A, Kemmer, L, Khalid, N, Khalilov, R, Khammarnia, M, Khan, E, Khan, G, Khan, M, Khang, Y, Khatab, K, Khater, A, Khater, M, Khayamzadeh, M, Khosravi, A, Kim, D, Kim, Y, Kimokoti, R, Kisa, A, Kisa, S, Kissoon, N, Kopec, J, Kosen, S, Koul, P, Koulmane Laxminarayana, S, Koyanagi, A, Krishan, K, Krishnamoorthy, V, Kuate Defo, B, Kucuk Bicer, B, Kulkarni, V, Kumar, G, Kumar, M, Kumar, N, Kurmi, O, Kusuma, D, La Vecchia, C, Lacey, B, Lalloo, R, Lami, F, Landires, I, Larsson, A, Lasrado, S, Lassi, Z, Lauriola, P, Lee, P, Lee, S, Lee, Y, Leigh, J, Leonardi, M, Lewycka, S, Li, B, Li, S, Liang, J, Lim, L, Limenih, M, Lin, R, Liu, X, Lodha, R, Lopez, A, Lozano, R, Lugo, A, Lunevicius, R, Mackay, M, Madhava Kunjathur, S, Magnani, F, Mahadeshwara Prasad, D, Maheri, M, Mahmoudi, M, Majeed, A, Maled, V, Maleki, A, Maleki, S, Malekzadeh, R, Malik, A, Malta, D, Mamun, A, Mansouri, B, Mansournia, M, Martinez, G, Martini, S, Martins-Melo, F, Masoumi, S, Maulik, P, Mcalinden, C, Mcgrath, J, Medina-Solis, C, Mehrabi Nasab, E, Mejia-Rodriguez, F, Memish, Z, Mendoza, W, Menezes, R, Mengesha, E, Mensah, G, Meretoja, A, Meretoja, T, Mersha, A, Mestrovic, T, Miazgowski, B, Miazgowski, T, Michalek, I, Miller, T, Mini, G, Miri, M, Mirica, A, Mirrakhimov, E, Mirzaei, H, Mirzaei, M, Moazen, B, Moghadaszadeh, M, Mohajer, B, Mohamad, O, Mohammad, Y, Mohammadi, S, Mohammadian-Hafshejani, A, Mohammed, S, Mokdad, A, Molokhia, M, Monasta, L, Mondello, S, Moni, M, Moore, C, Moradi, G, Moradi, M, Moradzadeh, R, Moraga, P, Morawska, L, Morrison, S, Mosser, J, Mousavi Khaneghah, A, Mustafa, G, Naderi, M, Nagarajan, A, Nagaraju, S, Naghavi, M, Naghshtabrizi, B, Naimzada, M, Nangia, V, Narasimha Swamy, S, Nascimento, B, Naveed, M, Nazari, J, Ndejjo, R, Negoi, I, Negoi, R, Nena, E, Nepal, S, Netsere, H, Nguefack-Tsague, G, Ngunjiri, J, Nguyen, C, Nguyen, H, Nigatu, Y, Nigussie, S, Nixon, M, Nnaji, C, Nomura, S, Noor, N, Noubiap, J, Nunez-Samudio, V, Nwatah, V, Oancea, B, Odukoya, O, Ogbo, F, Olusanya, B, Olusanya, J, Omar Bali, A, Onwujekwe, O, Ortiz, A, Otoiu, A, Otstavnov, N, Otstavnov, S, Owolabi, M, P A, M, Padubidri, J, Pakhale, S, Pakshir, K, Pal, P, Palladino, R, Pana, A, Panda-Jonas, S, Pandey, A, Pandi-Perumal, S, Pangaribuan, H, Pardo-Montano, A, Park, E, Patel, S, Patton, G, Pawar, S, Pazoki Toroudi, H, Peden, A, Pepito, V, Peprah, E, Pereira, J, Perez-Gomez, J, Perico, N, Pesudovs, K, Pilgrim, T, Pinheiro, M, Piradov, M, Pirsaheb, M, Platts-Mills, J, Pokhrel, K, Postma, M, Pourjafar, H, Prada, S, Prakash, S, Pupillo, E, Quazi Syed, Z, Rabiee, N, Radfar, A, Rafiee, A, Rafiei, A, Raggi, A, Rahimzadeh, S, Rahman, M, Rahmani, A, Ramezanzadeh, K, Rana, J, Ranabhat, C, Rao, S, Rasella, D, Rastogi, P, Rathi, P, Rawaf, D, Rawaf, S, Rawasia, W, Rawassizadeh, R, Reiner, R, Remuzzi, G, Renzaho, A, Reshmi, B, Resnikoff, S, Rezaei, N, Rezapour, A, Riahi, S, Ribeiro, D, Rickard, J, Roever, L, Ronfani, L, Rothenbacher, D, Rubagotti, E, Rumisha, S, Ryan, P, Saddik, B, Sadeghi, E, Saeedi Moghaddam, S, Sagar, R, Sahebkar, A, Salahshoor, M, Salehi, S, Salem, M, Salimzadeh, H, Salomon, J, Samodra, Y, Samy, A, Sanabria, J, Santric-Milicevic, M, Saraswathy, S, Sarker, A, Sarrafzadegan, N, Sarveazad, A, Sathian, B, Sathish, T, Sattin, D, Saxena, S, Saya, G, Saylan, M, Schiavolin, S, Schlaich, M, Schwebel, D, Schwendicke, F, Senthilkumaran, S, Sepanlou, S, Servan-Mori, E, Sha, F, Shafaat, O, Shahabi, S, Shahbaz, M, Shaheen, A, Shahid, I, Shaikh, M, Shakiba, S, Shalash, A, Shams-Beyranvand, M, Shannawaz, M, Sharafi, K, Sheikh, A, Sheikhbahaei, S, Shiferaw, W, Shigematsu, M, Shin, J, Shiri, R, Shiue, I, Shuval, K, Siddiqi, T, Sidemo, N, Sigfusdottir, I, Sigurvinsdottir, R, Silva, J, Silverberg, J, Simonetti, B, Singh, B, Singh, J, Singhal, D, Sinha, D, Skiadaresi, E, Skryabin, V, Skryabina, A, Sleet, D, Sobaih, B, Sobhiyeh, M, Soltani, S, Soriano, J, Spurlock, E, Sreeramareddy, C, Steiropoulos, P, Stokes, M, Stortecky, S, Sufiyan, M, Suliankatchi Abdulkader, R, Sulo, G, Swope, C, Sykes, B, Szeto, M, Szocska, M, Tabares-Seisdedos, R, Tadesse, E, Taherkhani, A, Tamiru, A, Tareque, M, Tehrani-Banihashemi, A, Temsah, M, Tesfay, F, Tessema, G, Tessema, Z, Thankappan, K, Thapar, R, Tolani, M, Tovani-Palone, M, Traini, E, Tran, B, Tripathy, J, Tsapparellas, G, Tsatsakis, A, Tudor Car, L, Uddin, R, Ullah, A, Umeokonkwo, C, Unim, B, Unnikrishnan, B, Upadhyay, E, Usman, M, Vacante, M, Vaezi, M, Valadan Tahbaz, S, Valdez, P, Vasankari, T, Venketasubramanian, N, Verma, M, Violante, F, Vlassov, V, Vo, B, Vu, G, Wado, Y, Waheed, Y, Wamai, R, Wang, Y, Ward, P, Werdecker, A, Westerman, R, Wickramasinghe, N, Wilner, L, Wiysonge, C, Wu, A, Wu, C, Xie, Y, Yahyazadeh Jabbari, S, Yamagishi, K, Yandrapalli, S, Yaya, S, Yazdi-Feyzabadi, V, Yip, P, Yonemoto, N, Yoon, S, Younis, M, Yousefi, Z, Yousefinezhadi, T, Yu, C, Yusuf, S, Zaidi, S, Zaman, S, Zamani, M, Zamanian, M, Zastrozhin, M, Zastrozhina, A, Zhang, Y, Zhang, Z, Zhao, X, Ziapour, A, Hay, S, Murray, C, Wang, H, Kassebaum, N, and Lee Kong Chian School of Medicine (LKCMedicine)
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Male ,Perinatal care ,Newborn care ,STILLBIRTHS ,RJ101 ,UNDER-5 MORTALITY ,Psychological intervention ,010501 environmental sciences ,Infant mortality ,Global Health ,01 natural sciences ,0302 clinical medicine ,RA0421 ,Cause of Death ,Infant Mortality ,Global health ,Life Tables ,Healthcare improvements ,030212 general & internal medicine ,610 Medicine & health ,Child ,COVID-19 ,Humans ,Infant ,SARS-CoV-2 ,Sustainable Development ,11 Medical and Health Sciences ,Cause of death ,Life Table ,Mortality rate ,1. No poverty ,Public Health, Global Health, Social Medicine and Epidemiology ,General Medicine ,Articles ,Hälsovetenskaper ,Mortality analyses ,3. Good health ,Child, Preschool ,SDG 1 - No Poverty ,Child Mortality ,Female ,Life Sciences & Biomedicine ,Human ,Child mortality ,COUNTRIES ,DEATHS ,Infants -- Mortalitat ,GBD ,03 medical and health sciences ,Medicine, General & Internal ,SDG 3 - Good Health and Well-being ,Life tables ,under-5 mortality rate ,General & Internal Medicine ,Health Sciences ,Neonatal deaths ,medicine ,SYSTEMATIC ANALYSIS ,Medicine [Science] ,Infants -- Salut ,Preschool ,0105 earth and related environmental sciences ,Science & Technology ,Infants nadons -- Salut ,business.industry ,Infants nadons -- Mortalitat ,INFORM ,Infant, Newborn ,Neonatal and child health ,Sustainable Development Goal 3.2 ,GBD 2019 Under-5 Mortality Collaborators ,medicine.disease ,Newborn ,TRENDS ,Sustainable Development Goal ,Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi ,Deaths ,3121 General medicine, internal medicine and other clinical medicine ,RG ,business ,Systematic Analysis ,Malaria ,Demography - Abstract
Background: Sustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths, and reduction of death of children younger than 5 years to less than 25 per 1000 livebirths, for each country by 2030. To understand current rates, recent trends, and potential trajectories of child mortality for the next decade, we present the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 findings for all-cause mortality and cause-specific mortality in children younger than 5 years of age, with multiple scenarios for child mortality in 2030 that include the consideration of potential effects of COVID-19, and a novel framework for quantifying optimal child survival. Methods: We completed all-cause mortality and cause-specific mortality analyses from 204 countries and territories for detailed age groups separately, with aggregated mortality probabilities per 1000 livebirths computed for neonatal mortality rate (NMR) and under-5 mortality rate (U5MR). Scenarios for 2030 represent different potential trajectories, notably including potential effects of the COVID-19 pandemic and the potential impact of improvements preferentially targeting neonatal survival. Optimal child survival metrics were developed by age, sex, and cause of death across all GBD location-years. The first metric is a global optimum and is based on the lowest observed mortality, and the second is a survival potential frontier that is based on stochastic frontier analysis of observed mortality and Healthcare Access and Quality Index. Findings: Global U5MR decreased from 71·2 deaths per 1000 livebirths (95% uncertainty interval [UI] 68·3-74·0) in 2000 to 37·1 (33·2-41·7) in 2019 while global NMR correspondingly declined more slowly from 28·0 deaths per 1000 live births (26·8-29·5) in 2000 to 17·9 (16·3-19·8) in 2019. In 2019, 136 (67%) of 204 countries had a U5MR at or below the SDG 3.2 threshold and 133 (65%) had an NMR at or below the SDG 3.2 threshold, and the reference scenario suggests that by 2030, 154 (75%) of all countries could meet the U5MR targets, and 139 (68%) could meet the NMR targets. Deaths of children younger than 5 years totalled 9·65 million (95% UI 9·05-10·30) in 2000 and 5·05 million (4·27-6·02) in 2019, with the neonatal fraction of these deaths increasing from 39% (3·76 million [95% UI 3·53-4·02]) in 2000 to 48% (2·42 million; 2·06-2·86) in 2019. NMR and U5MR were generally higher in males than in females, although there was no statistically significant difference at the global level. Neonatal disorders remained the leading cause of death in children younger than 5 years in 2019, followed by lower respiratory infections, diarrhoeal diseases, congenital birth defects, and malaria. The global optimum analysis suggests NMR could be reduced to as low as 0·80 (95% UI 0·71-0·86) deaths per 1000 livebirths and U5MR to 1·44 (95% UI 1·27-1·58) deaths per 1000 livebirths, and in 2019, there were as many as 1·87 million (95% UI 1·35-2·58; 37% [95% UI 32-43]) of 5·05 million more deaths of children younger than 5 years than the survival potential frontier. Interpretation: Global child mortality declined by almost half between 2000 and 2019, but progress remains slower in neonates and 65 (32%) of 204 countries, mostly in sub-Saharan Africa and south Asia, are not on track to meet either SDG 3.2 target by 2030. Focused improvements in perinatal and newborn care, continued and expanded delivery of essential interventions such as vaccination and infection prevention, an enhanced focus on equity, continued focus on poverty reduction and education, and investment in strengthening health systems across the development spectrum have the potential to substantially improve U5MR. Given the widespread effects of COVID-19, considerable effort will be required to maintain and accelerate progress. This article was supported by the European Research Council, ERC 848325. Alberto Ortiz was supported by FIS/Fondos FEDER (PI18/01366, PI19/00588, PI19/00815, DTS18/00032, ERA-PerMed-JTC2018 (KIDNEY ATTACK AC18/00064 and PERSTIGAN AC18/00071, ISCIII-RETIC REDinREN RD016/0009). Daniela Ribeiro acknowledges the financial support from the European Union [FEDER funds through COMPETE, POCI-01-0145-FEDER-029253). Joan B Soriano acknowledges support from the Centro de Investigación en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III (ISCIII), Madrid, Spain Funding: Bill & Melinda Gates Foundation
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34. Screening for Atrial Fibrillation in Sub-Saharan Africa
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Jacobs, M. S., Adeoye, A. M., Owolabi, M. O., Tieleman, R. G., Postma, M. J., Van Hulst, M., Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), and Microbes in Health and Disease (MHD)
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Community and Home Care ,Epidemiology ,Cost-Benefit Analysis ,Anticoagulants ,Nigeria ,Atrial Fibrillation ,Screening ,Health economics ,stroke prevention ,Stroke ,RC666-701 ,Stroke prevention ,Feasibility Studies ,Humans ,Mass Screening ,Diseases of the circulatory (Cardiovascular) system ,Quality-Adjusted Life Years ,Public aspects of medicine ,RA1-1270 ,Cardiology and Cardiovascular Medicine ,Original Research - Abstract
Background: Cardiovascular disease reflects a major burden of non-communicable disease in Sub-Saharan Africa (SSA). Early detection and treatment of atrial fibrillation (AF), as a preventive measure against stroke, is currently not in the scope of the World Health Organization recommendation to reduce cardiovascular disease.Objective: We hypothesized that screening for AF would be an important approach to determine the true AF prevalence in the general population in African countries and to identify asymptomatic AF patients at risk for stroke to optimize prevention.Methods: A decision analytic model was developed to study the health-economic impact of AF screening in Nigeria over a life-time horizon. The patient population explored in the model was a population of newly detected AF cases that would be diagnosed with a one-time systematic screening for AF with a single lead ECG device in community health centres across Nigeria.Conclusions: The health gain per newly detected AF patient (N = 31,687) was 0.41 QALY at a cost of $5,205 per patient with 100% NOAC use, leading to an ICER of $12,587 per QALY gained. The intervention was cost-effective with a 99.9% warfarin use with an ICER of $1,363 per QALY gained. The total cost of a single screening session was $7.3 million for the total screened population in Nigeria or $1.60 per patient screened. Screening for AF to detect AF patients in need for stroke prevention can be a cost-effective intervention in the Sub-Saharan region, depending on type of anticoagulant used and drug costs.
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35. Cost-minimisation analysis of a treat-and-extend regimen with anti-VEGFs in patients with neovascular age-related macular degeneration
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Quist, S. W., primary, de Jong, L. A., additional, van Asten, F., additional, Knoester, P., additional, Postma, M. J., additional, and Freriks, R. D., additional
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- 2021
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36. Costs of Chemotherapy in the Treatment of Colorectal Cancer
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Jansman, F. G. A. and Postma, M. J.
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- 2006
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37. Differential Time Preferences for Money and Quality of Life
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Parouty, M. B. Y., Le, H. H., Krooshof, D., and Postma, M. J.
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- 2014
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38. The pharmacists’ potential to provide targets for interventions to optimize pharmacotherapy in patients with asthma
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van Boven, J. F. M., Hiddink, E. G., Stuurman-Bieze, A. G. G., Schuiling-Veninga, C. C. M., Postma, M. J., and Vegter, S.
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- 2013
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39. Epidemiological Models and Socioeconomic Information: Methodological Aspects of AIDS/HIV Scenario Analysis
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Jager, J. C., Postma, M. J., van den Boom, F. M., Reinking, D. P., Borleffs, J. C. C., Heisterkamp, S. H., van Druten, J. A. M., Ruitenberg, E. J., Davis, K., editor, van Eimeren, W., editor, Schwefel, Detlef, editor, Leidl, Reiner, editor, Rovira, Joan, editor, and Drummond, Michael F., editor
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- 1990
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40. Cost-Effectiveness of Bosutinib for the Treatment of Adult Patients with Chronic Phase Chronic Myeloid Leukemia in the Second-Line Setting
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Muresan, B., primary, Mamolo, C., additional, Cappelleri, J. C., additional, Postma, M. J., additional, and Heeg, B., additional
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- 2021
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41. Universal HIV Screening of Pregnant Women in England: Cost Effectiveness Analysis
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Postma, M. J., Beck, E. J., Mandalia, S., Sherr, L., Walters, M. D. S., Houweling, H., and Jager, J. C.
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- 1999
42. Investments in blood safety improve the availability of blood to underserved areas in a sub-Saharan African country
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Pitman, J. P., Wilkinson, R., Basavaraju, S. V., von Finckenstein, B., Smit Sibinga, C., Marfin, A. A., Postma, M. J., Mataranyika, M., Tobias, J., and Lowrance, D. W.
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- 2014
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43. The role of Streptococcus pneumoniae in community-acquired pneumonia among adults in Europe: a meta-analysis
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Rozenbaum, M. H., Pechlivanoglou, P., van der Werf, T. S., Lo-Ten-Foe, J. R., Postma, M. J., and Hak, E.
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- 2013
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44. Evaluating interventions to improve somatic health in severe mental illness: a systematic review
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van Hasselt, F. M., Krabbe, P. F. M., van Ittersum, D. G., Postma, M. J., and Loonen, A. J. M.
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- 2013
- Full Text
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45. O2-S4.02 Cost-effectiveness of screening for Chlamydia trachomatis in Dutch pregnant women
- Author
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Rours, G I J G, Verkooijen, R P, Verbrugh, H A, and Postma, M J
- Published
- 2011
- Full Text
- View/download PDF
46. Diagnostic accuracy of culture-based and PCR-based detection tests for methicillin-resistant Staphylococcus aureus: a meta-analysis
- Author
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Luteijn, J. M., Hubben, G. A. A., Pechlivanoglou, P., Bonten, M. J., and Postma, M. J.
- Published
- 2011
- Full Text
- View/download PDF
47. 1202The incidence, treatment and mortality of new-onset atrial fibrillation patients at the intensive care unit
- Author
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Jacobs, M, primary, Loef, B G, additional, Reidinga, A C, additional, Postma, M J, additional, Van Hulst, M, additional, and Tieleman, R G, additional
- Published
- 2019
- Full Text
- View/download PDF
48. Health economic methodology illustrated with recent work on Chlamydia screening: the concept of extended dominance
- Author
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Postma, M J, de Vries, R, Welte, R, and Edmunds, W J
- Published
- 2008
- Full Text
- View/download PDF
49. Application and acceptance of complex survival extrapolation methods in hta submissions
- Author
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van Oostrum, P., Garcia, A., Ouwens, M. J., Postma, M. J., Buskens, E., Heeg, B., Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Microbes in Health and Disease (MHD), and PharmacoTherapy, -Epidemiology and -Economics
- Published
- 2018
50. Comparing mixture cure models with standard parametric models within three - and five- state partition survival frameworks
- Author
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van Oostrum, P., Buskens, E., Ouwens, M. J., Postma, M. J., Heeg, B., Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Microbes in Health and Disease (MHD), and PharmacoTherapy, -Epidemiology and -Economics
- Published
- 2018
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