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12 results on '"Postma, Doerine J."'

3. Medicine shortages: impact behind numbers

Author

Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, PECP - Centre for Pharmaceutical Policy and Regulation, Postma, Doerine J., Notenboom, Kim, De Smet, Peter A.G.M., Leufkens, Hubert G.M., Mantel-Teeuwisse, Aukje K., Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, PECP - Centre for Pharmaceutical Policy and Regulation, Postma, Doerine J., Notenboom, Kim, De Smet, Peter A.G.M., Leufkens, Hubert G.M., and Mantel-Teeuwisse, Aukje K.

Published
2023

4. Impact of medicine shortages on patients - a framework and application in the Netherlands

Author

Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Postma, Doerine J., De Smet, Peter A.G.M., Notenboom, Kim, Leufkens, Hubert G.M., Mantel-Teeuwisse, Aukje K., Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Postma, Doerine J., De Smet, Peter A.G.M., Notenboom, Kim, Leufkens, Hubert G.M., and Mantel-Teeuwisse, Aukje K.

Published
2022

6. Drug Shortages From the Perspectives of Authorities and Pharmacy Practice in the Netherlands: An Observational Study

Author

Postma, Doerine J, De Smet, Peter A G M, Gispen-de Wied, Christine C, Leufkens, Hubert G M, Mantel-Teeuwisse, Aukje K, Postma, Doerine J, De Smet, Peter A G M, Gispen-de Wied, Christine C, Leufkens, Hubert G M, and Mantel-Teeuwisse, Aukje K

Abstract

Background: Drug shortages are a potential threat to public health. Reliable data on drug shortages is limited. The objective was to examine the extent and nature of potential drug shortages signaled by authorities and pharmacy practice in the Netherlands Materials and Methods: The primary working systems of Dutch authorities (Medicines Evaluation Board and Health and Youth Care Inspectorate) and the archives of pharmacy practice (Royal Dutch Pharmacists Association) from 2012 to 2015 were searched for number, characteristics, overlap, and date of signals on potential drug shortages. Also, the product characteristics of the potential drug shortages were analyzed from the two different sources Results: Authorities detected 2.6 times more signals on potential shortages than pharmacy practice. Only 438 (8%) out of 5,731 potential drug shortages were detected by both authorities and pharmacy practice. Signals were detected later by authorities than by pharmacy practice, especially on potential permanent shortages (median difference -180 days (IQR: -4 to -405 days)). Authorities detected by majority (72%) signals related to permanent shortages with relative overrepresentation of rectal products and anti-infectives for systemic use. In contrast, pharmacy practice detected by majority (71%) signals related to temporary shortages with relative overrepresentation of ocular and cutaneous products, anti-infectives for systemic use, products for sensory organs and dermatologicals. Conclusions: Authorities and pharmacy practice detected different signals on potential drug shortages with little overlap. Combining data from both authorities and pharmacy practice seems to be necessary in order to gain a more complete overview and maximum insight in potential drug shortages at a national level. Moreover, the finding that authorities were informed later than pharmacy practice causes concerns in terms of opportunities for authorities to assist pharmacy practice to find solutions fo

Published
2018

8. Drug Shortages From the Perspectives of Authorities and Pharmacy Practice in the Netherlands: An Observational Study

Author

Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Postma, Doerine J, De Smet, Peter A G M, Gispen-de Wied, Christine C, Leufkens, Hubert G M, Mantel-Teeuwisse, Aukje K, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, Postma, Doerine J, De Smet, Peter A G M, Gispen-de Wied, Christine C, Leufkens, Hubert G M, and Mantel-Teeuwisse, Aukje K

Published
2018

12. Identifying Medicine Shortages With the Twitter Social Network: Retrospective Observational Study.

Author

Postma DJ, Heijkoop MLA, De Smet PAGM, Notenboom K, Leufkens HGM, and Mantel-Teeuwisse AK

Subjects
Humans, Retrospective Studies, Pharmaceutical Preparations supply & distribution, Netherlands, Social Media statistics & numerical data
Abstract

Background: Early identification is critical for mitigating the impact of medicine shortages on patients. The internet, specifically social media, is an emerging source of health data., Objective: This study aimed to explore whether a routine analysis of data from the Twitter social network can detect signals of a medicine shortage and serve as an early warning system and, if so, for which medicines or patient groups., Methods: Medicine shortages between January 31 and December 1, 2019, were collected from the Dutch pharmacists' society's national catalog Royal Dutch Pharmacists Association (KNMP) Farmanco. Posts on these shortages were collected by searching for the name, the active pharmaceutical ingredient, or the first word of the brand name of the medicines in shortage. Posts were then selected based on relevant keywords that potentially indicated a shortage and the percentage of shortages with at least 1 post was calculated. The first posts per shortage were analyzed for their timing (median number of days, including the IQR) versus the national catalog, also stratified by disease and medicine characteristics. The content of the first post per shortage was analyzed descriptively for its reporting stakeholder and the nature of the post., Results: Of the 341 medicine shortages, 102 (29.9%) were mentioned on Twitter. Of these 102 shortages, 18 (5.3% of the total) were mentioned prior to or simultaneous to publication by KNMP Farmanco. Only 4 (1.2%) of these were mentioned on Twitter more than 14 days before. On average, posts were published with a median delay of 37 (IQR 7-81) days to publication by KNMP Farmanco. Shortages mentioned on Twitter affected a greater number of patients and lasted longer than those that were not mentioned. We could not conclusively relate either the presence or absence on Twitter to a disease area or route of administration of the medicine in shortage. The first posts on the 102 shortages were mainly published by patients (n=51, 50.0%) and health care professionals (n=46, 45.1%). We identified 8 categories of nature of content. Sharing personal experience (n=44, 43.1%) was the most common category., Conclusions: The Twitter social network is not a suitable early warning system for medicine shortages. Twitter primarily echoes already-known information rather than spreads new information. However, Twitter or potentially any other social media platform provides the opportunity for future qualitative research in the increasingly important field of medicine shortages that investigates how a larger population of patients is affected by shortages., (©Doerine J Postma, Magali L A Heijkoop, Peter A G M De Smet, Kim Notenboom, Hubert G M Leufkens, Aukje K Mantel-Teeuwisse. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 06.08.2024.)

Published
2024
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