1. The effectiveness of non-pharmacological or non-surgical interventions on the Health Related Quality of Life of People with Parkinson's Disease: a protocol of systematic review of randomized controlled trials
- Author
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Alcântara-Silva TRdM, Paula TCd, Porto Cc, and Citon Lf
- Subjects
Health related quality of life ,Protocol (science) ,medicine.medical_specialty ,Parkinson's disease ,business.industry ,medicine.disease ,law.invention ,Randomized controlled trial ,law ,Medicine ,business ,Intensive care medicine ,Surgical interventions ,Non pharmacological - Abstract
Background: Parkinson's disease (PD) is the second most common neurodegenerative, progressive and disabling disease affecting the elderly population, with by motor and non-motor symptoms that interfere with the Health-Related Quality of Life (HRQoL) of this population. Currently, there are still no resources to cure the disease, so the main treatment method used to reduce symptoms is based initially on pharmacological therapy, and in some cases, surgery is recommended. However, some unconventional interventions have been used, showing good results for the improvement of symptoms that also include HRQoL. Therefore, this investigation aimed to identify non-pharmacological or non-surgical interventions, in randomized clinical studies (RCTs) and their effectiveness in improving the HRQoL of people with PD.Methods: Systematic review, guided by the PRISMA method, using the SciELO, MEDLINE / PubMed, Cochrane Library, Web of Science, Scopus, and Brazilian Digital Library of Theses and Dissertations databases - BDTD, through CAFe Access on the CAPES / MEC Journals portal. "Quality of Life" - "Parkinson’s Disease" - "Randomized Controlled Trial", were the keywords used. Articles were selected by 2 independent reviewers using a third for doubts / discrepancies. Articles published until October 2020, in languages English, Portuguese and Spanish, RCTs, with non-pharmacological or non-surgical interventions, population diagnosed with PD, at any age or stage of the disease will be included. A narrative synthesis will be used to summarize the results and discussion, as well as a methodological evaluation of the RCTs using Cochrane Collaboration's risk of bias tool.Discussion: This review will identify the effectiveness of non-pharmacological and non-surgical interventions aimed at improving the HRQoL of people with PD, based on assessment instruments related to the proposed theme, based on RCT. Therefore, the findings show the current panorama of studies performed, discussion about their clinical applicability, as well as suggestions for improvements of future trials.Registration of Systematic Review: CRD42021221383
- Published
- 2021