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2. Respiratory Care for Neonates With Congenital Heart Disease.

Author

Bronicki, Ronald A, Benitz, William E, Buckley, Jason R, Yarlagadda, Vamsi V, Porta, Nicolas FM, Agana, Devon O, Kim, Minso, and Costello, John M

Subjects
Humans, Heart Defects, Congenital, Retrospective Studies, Infant, Newborn, Medical and Health Sciences, Psychology and Cognitive Sciences, Pediatrics
Published
2022

3. Neonatal Risk Factors for Pulmonary Vein Stenosis in Infants Born Preterm with Severe Bronchopulmonary Dysplasia

Author

Piazza, Anthony, Sysyn, Gregory, Lucke, Ashley, Pont, Molly, Black, Allison, Coghill, Carl, Hansen, Anne, Pallotto, Eugenia, Murthy, Karna, Falciglia, Gustave, Haberman, Beth, Nesterenko, Tetyana, Bartman, Thomas, Carroll, Laura, Smith, Danielle, Bourque, Stephanie, Natarjan, Girija, Chi, Annie, Johnson, Yvette, Gotiolo, Annmarie, Katarkan, Lakshmi, Reber, Kristina, Rose, Rebecca, Lindower, Julie, Weiner, Julie, Chapman, Rachel, Menda, Nina, Weems, Mark, Downey, Ann, Lagatta, Joanne, Joe, Priscilla, Tipple, Trent, Williams, Patricia, Birge, Nicole, Mikhael, Michel, Dereddy, Narendra, Wadhawan, Rajan, Weiss, Aaron, Padula, Michael, Quinones, Vilarmis, Griffiths, Pam, Yanowitz, Toby, Bendel-Stenzel, Ellen, Ling, Con Yee, Speziale, Mark, DiGeronimo, Robert, Jacobsen, Elizabeth, Brozanski, Beverly, Rao, Rakesh, Van Marter, Linda, Lee, Kyong-Soon, Short, Billie Lou, Sullivan, Kevin, Welch, Cherrie, McArthur, Erica, Zaniletti, Isabella, Sharma, Megha, Ball, Molly, Porta, Nicolas, Grover, Theresa, Levy, Philip, Hamrick, Shannon, and Vyas-Read, Shilpa

Published
2024
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4. Association Between Urinary Biomarkers and CKD in Extremely Low Gestational Age Neonates

Author

Thomas, Billy, Elhassan, Nahed, Mulkey, Sarah, Dydynski, Philip, Vijayamadhavan, Vivek K., Mulrooney, Neil, Yoder, Bradley, Kase, Jordan S., Check, Jennifer, Gogcu, Semsa, Osterholm, Erin, Ramel, Sara, Bendel, Catherine, Gale, Cheryl, George, Thomas, Georgieff, Michael, Gisslen, Tate, Guiang, Sixto, III, Hall, Anne, Johnson, Dana, Pfister, Katie, Podgorski, Heather, Roberts, Kari, Stepka, Erin, Engel, Melissa, Kamrath, Heidi, Scheurer, Johannah, Hanson, Angela, Satrom, Katherine, Pfister, Susan, Simones, Ann, Plummer, Erin, Zorn, Elizabeth, Martin, Camilia R., O’Reilly, Deirdre, Porta, Nicolas, Bazacliu, Catalina, Williams, Jonathan, Rajderkar, Dhanashree, Northington, Frances, Valdez, Raul Chavez, Beauman, Sandra, Saurabhkumar, Patel, Diaz-Barbosa, Magaly, Serize, Arturo, Jordan, Jorge, Ott, Debbie, Mora, Ariana Franco, Hedrick, Pamela, Flynn, Vicki, Silvia, Amy, Clopp, Bailey, Feltner, John B., Esposito, Isabella, Hauge, Stephanie, Nikirk, Samantha, Purnell, Andrea, Loy, Emilie, Sikes, Natalie, Mason, Melanie, McConnell, Jana, Brown, Tiffany, Harrison, Henry, Pearson, Denise, Drake, Tammy, Wright, Jocelyn, Walden, Debra, Guy, Annette, Nason, Jennifer, Talbot, Morgan, Lee, Kristen, Penny, Sarah, Boles, Terri, Drummond, Melanie, Kohlleppel, Katy, Kathen, Charmaine, Kaletka, Brian, Gonzales, Shania, Worwa, Cathy, Fisher, Molly, Richter, Tyler, Ginder, Alexander, Reich, Brixen, Rau, Carrie, Loertscher, Manndi, Bledsoe, Laura, McGrath, Kandace, Lewis, Kimberlee Weaver, Burnett, Jill, Schaefer, Susan, Bird, Karie, Giblin, Clare, Daly, Rita, Lanier, Kristi, Warden, Kelly, Wassenaar, Jenna, Ericksen, Jensina, Davern, Bridget, Osborne, Mary Pat, Gregorich, Brittany, Talele, Neha, Obregon, Evelyn, Ziyeh, Tiglath, Clarke, Molly, Wegner, Rachel E., Patel, Palak, Schau, Molly, Russow, Annamarie, Curry, Kelly, Sinnamon, Susan, Barnhart, Lisa, Parkinson, Charlamaine, Hanson, Mary, Kuan, Elizabeth, Lacy, Conra Backstrom, Galvis, Edshelee M., Bombino, Susana, Martinez, Denise, Bell, Suzi, Long, Corrie, Longa, Cathy, Westerveld, Michael, McConkey, Stacy, Hay, Anne, Natarajan, Niranjana, Gaudette, Shari, Cobb, Sarah, Sharp, Gregory, Schumacher, Elizabeth, Schuschke, Leslie, Frey, Charlotte, Fierro, Mario, Gilmore, Lois, Lundequam, Pamela, Hoekstra, Ronald, Ketko, Anastasia, Perdue, Nina, Cunningham, Sean, Stout, Kelly, Hall, Becky, Morshedzadeh, Galina, Ostrander, Betsy, Winter, Sarah, Cox, Lauren, Rainaldi, Matthew A., Hensley, Sarah, Morris, Melissa, Roberts, Dia, Tuttle, Melissa, Boys, Christopher, Hultgren, Solveig, Pierpont, Elizabeth I., Fahim, Nancy, George, Tom, King, Kelly E., Bataglia, Katherine, Neis, Cathy, Bergeron, Mark, Miller, Cristina, Accomando, Cara, Gavin, Jennifer Anne, Maczek, Elizabeth, Marakovitz, Susan, Knorr, Aimee, Smith, Vincent C., Stewart, Jane E., Weissbourd, Marie, deRegnier, Raye-Ann, Matoba, Nana, Heaton, Shelly C., Cascio, Erika M., Brady, Janet, Ghosh, Suman, Ditto, Jessica, Leppert, Mary, Lowe, Jean, Fuller, Janell, DuPont, Tara, Ohls, Robin, Kloska, Pamela, Patel, Saurabh, Carbonell, Lauren, Patino-Fernandez, Anna Maria, de Lerma, Carmen, McDonough, Kelly, De Cortada, Maiana, Chavis, Lacy, Shannon, Jane, Hingorani, Sangeeta R., Schmicker, Robert H., Halloran, Brian, Brophy, Patrick, Heagerty, Patrick J., Juul, Sandra, Goldstein, Stuart L., and Askenazi, David

Published
2024
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6. Predicting treatment of pulmonary hypertension at discharge in infants with congenital diaphragmatic hernia

Author

Mahmood, Burhan, Murthy, Karna, Rintoul, Natalie, Weems, Mark, Keene, Sarah, Brozanski, Beverly, DiGeronimo, Robert, Haberman, Beth, Hedrick, Holly, Gien, Jason, Seabrook, Ruth, Ali, Noorjahan, Chapman, Rachel, Daniel, John, Harrison, Allen, Johnson, Yvette, Porta, Nicolas F. M., Uhing, Michael, Zaniletti, Isabella, and Grover, Theresa R.

Published
2022
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7. A comparison of newer classifications of bronchopulmonary dysplasia: findings from the Children’s Hospitals Neonatal Consortium Severe BPD Group

Author

Vyas-Read, Shilpa, Logan, J. Wells, Cuna, Alain C., Machry, Joana, Leeman, Kristin T., Rose, Rebecca S., Mikhael, Michel, Wymore, Erica, Ibrahim, John W., DiGeronimo, Robert J., Yallapragada, Sushmita, Haberman, Beth E., Padula, Michael A., Porta, Nicolas F., Murthy, Karna, Nelin, Leif D., Coghill, Carl H., Zaniletti, Isabella, Savani, Rashmin C., Truog, William, Engle, William A., and Lagatta, Joanne M.

Published
2022
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8. Association Between Urinary Biomarkers and CKD in Extremely Low Gestational Age Neonates

Author

Hingorani, Sangeeta R., primary, Schmicker, Robert H., additional, Halloran, Brian, additional, Brophy, Patrick, additional, Heagerty, Patrick J., additional, Juul, Sandra, additional, Goldstein, Stuart L., additional, Askenazi, David, additional, Thomas, Billy, additional, Elhassan, Nahed, additional, Mulkey, Sarah, additional, Dydynski, Philip, additional, Vijayamadhavan, Vivek K., additional, Mulrooney, Neil, additional, Yoder, Bradley, additional, Kase, Jordan S., additional, Check, Jennifer, additional, Gogcu, Semsa, additional, Osterholm, Erin, additional, Ramel, Sara, additional, Bendel, Catherine, additional, Gale, Cheryl, additional, George, Thomas, additional, Georgieff, Michael, additional, Gisslen, Tate, additional, Guiang, Sixto, additional, Hall, Anne, additional, Johnson, Dana, additional, Pfister, Katie, additional, Podgorski, Heather, additional, Roberts, Kari, additional, Stepka, Erin, additional, Engel, Melissa, additional, Kamrath, Heidi, additional, Scheurer, Johannah, additional, Hanson, Angela, additional, Satrom, Katherine, additional, Pfister, Susan, additional, Simones, Ann, additional, Plummer, Erin, additional, Zorn, Elizabeth, additional, Martin, Camilia R., additional, O’Reilly, Deirdre, additional, Porta, Nicolas, additional, Bazacliu, Catalina, additional, Williams, Jonathan, additional, Rajderkar, Dhanashree, additional, Northington, Frances, additional, Valdez, Raul Chavez, additional, Beauman, Sandra, additional, Saurabhkumar, Patel, additional, Diaz-Barbosa, Magaly, additional, Serize, Arturo, additional, Jordan, Jorge, additional, Ott, Debbie, additional, Mora, Ariana Franco, additional, Hedrick, Pamela, additional, Flynn, Vicki, additional, Silvia, Amy, additional, Clopp, Bailey, additional, Feltner, John B., additional, Esposito, Isabella, additional, Hauge, Stephanie, additional, Nikirk, Samantha, additional, Purnell, Andrea, additional, Loy, Emilie, additional, Sikes, Natalie, additional, Mason, Melanie, additional, McConnell, Jana, additional, Brown, Tiffany, additional, Harrison, Henry, additional, Pearson, Denise, additional, Drake, Tammy, additional, Wright, Jocelyn, additional, Walden, Debra, additional, Guy, Annette, additional, Nason, Jennifer, additional, Talbot, Morgan, additional, Lee, Kristen, additional, Penny, Sarah, additional, Boles, Terri, additional, Drummond, Melanie, additional, Kohlleppel, Katy, additional, Kathen, Charmaine, additional, Kaletka, Brian, additional, Gonzales, Shania, additional, Worwa, Cathy, additional, Fisher, Molly, additional, Richter, Tyler, additional, Ginder, Alexander, additional, Reich, Brixen, additional, Rau, Carrie, additional, Loertscher, Manndi, additional, Bledsoe, Laura, additional, McGrath, Kandace, additional, Lewis, Kimberlee Weaver, additional, Burnett, Jill, additional, Schaefer, Susan, additional, Bird, Karie, additional, Giblin, Clare, additional, Daly, Rita, additional, Lanier, Kristi, additional, Warden, Kelly, additional, Wassenaar, Jenna, additional, Ericksen, Jensina, additional, Davern, Bridget, additional, Osborne, Mary Pat, additional, Gregorich, Brittany, additional, Talele, Neha, additional, Obregon, Evelyn, additional, Ziyeh, Tiglath, additional, Clarke, Molly, additional, Wegner, Rachel E., additional, Patel, Palak, additional, Schau, Molly, additional, Russow, Annamarie, additional, Curry, Kelly, additional, Sinnamon, Susan, additional, Barnhart, Lisa, additional, Parkinson, Charlamaine, additional, Hanson, Mary, additional, Kuan, Elizabeth, additional, Lacy, Conra Backstrom, additional, Galvis, Edshelee M., additional, Bombino, Susana, additional, Martinez, Denise, additional, Bell, Suzi, additional, Long, Corrie, additional, Longa, Cathy, additional, Westerveld, Michael, additional, McConkey, Stacy, additional, Hay, Anne, additional, Natarajan, Niranjana, additional, Gaudette, Shari, additional, Cobb, Sarah, additional, Sharp, Gregory, additional, Schumacher, Elizabeth, additional, Schuschke, Leslie, additional, Frey, Charlotte, additional, Fierro, Mario, additional, Gilmore, Lois, additional, Lundequam, Pamela, additional, Hoekstra, Ronald, additional, Ketko, Anastasia, additional, Perdue, Nina, additional, Cunningham, Sean, additional, Stout, Kelly, additional, Hall, Becky, additional, Morshedzadeh, Galina, additional, Ostrander, Betsy, additional, Winter, Sarah, additional, Cox, Lauren, additional, Rainaldi, Matthew A., additional, Hensley, Sarah, additional, Morris, Melissa, additional, Roberts, Dia, additional, Tuttle, Melissa, additional, Boys, Christopher, additional, Hultgren, Solveig, additional, Pierpont, Elizabeth I., additional, Fahim, Nancy, additional, George, Tom, additional, King, Kelly E., additional, Bataglia, Katherine, additional, Neis, Cathy, additional, Bergeron, Mark, additional, Miller, Cristina, additional, Accomando, Cara, additional, Gavin, Jennifer Anne, additional, Maczek, Elizabeth, additional, Marakovitz, Susan, additional, Knorr, Aimee, additional, Smith, Vincent C., additional, Stewart, Jane E., additional, Weissbourd, Marie, additional, deRegnier, Raye-Ann, additional, Matoba, Nana, additional, Heaton, Shelly C., additional, Cascio, Erika M., additional, Brady, Janet, additional, Ghosh, Suman, additional, Ditto, Jessica, additional, Leppert, Mary, additional, Lowe, Jean, additional, Fuller, Janell, additional, DuPont, Tara, additional, Ohls, Robin, additional, Kloska, Pamela, additional, Patel, Saurabh, additional, Carbonell, Lauren, additional, Patino-Fernandez, Anna Maria, additional, de Lerma, Carmen, additional, McDonough, Kelly, additional, De Cortada, Maiana, additional, Chavis, Lacy, additional, and Shannon, Jane, additional

Published
2024
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10. The Impact of Erythropoietin on Short- and Long-Term Kidney-Related Outcomes in Neonates of Extremely Low Gestational Age. Results of a Multicenter, Double-Blind, Placebo-Controlled Randomized Clinical Trial

Author

Juul, Sandra E., Comstock, Bryan A., Wadhawan, Rajan, Mayock, Dennis E., Courtney, Sherry E., Robinson, Tonya, Ahmad, Kaashif A., Bendel-Stenzel, Ellen, Baserga, Mariana, LaGamma, Edmund F., Downey, L. Corbin, Rao, Raghavendra, Fahim, Nancy, Lampland, Andrea, Frantz, Ivan D., III, Khan, Janine Y., Weiss, Michael, Gilmore, Maureen M., Ohls, Robin, Srinivasan, Nishant, Perez, Jorge E., McKay, Victor, Vu, Phuong T., Heagerty, Patrick J., Thomas, Billy, Elhassan, Nahed, Mulkey, Sarah, Dydynski, Philip, Vijayamadhavan, Vivek K., Mulrooney, Neil, Yoder, Bradley, Kase, Jordan S., Check, Jennifer, Gogcu, Semsa, Osterholm, Erin, Ramel, Sara, Bendel, Catherine, Gale, Cheryl, George, Thomas, Georgieff, Michael, Gisslen, Tate, Guiang, Sixto, III, Hall, Anne, Johnson, Dana, Pfister, Katie, Podgorski, Heather, Roberts, Kari, Stepka, Erin, Engel, Melissa, Kamrath, Heidi, Scheurer, Johannah, Hanson, Angela, Satrom, Katherine, Pfister, Susan, Simones, Ann, Plummer, Erin, Zorn, Elizabeth, Martin, Camilia R., O'Reilly, Deirdre, Porta, Nicolas, Bazacliu, Catalina, Williams, Jonathan, Rajderkar, Dhanashree, Northington, Frances, Valdez, Raul Chavez, Beauman, Sandra, Saurabhkumar, Patel, Diaz-Barbosa, Magaly, Serize, Arturo, Jordan, Jorge, Ott, Debbie, Mora, Ariana Franco, Hedrick, Pamela, Flynn, Vicki, Silvia, Amy, Clopp, Bailey, Feltner, John B., Esposito, Isabella, Hauge, Stephanie, Nikirk, Samantha, Purnell, Andrea, Loy, Emilie, Sikes, Natalie, Mason, Melanie, McConnell, Jana, Brown, Tiffany, Harrison, Henry, Pearson, Denise, Drake, Tammy, Wright, Jocelyn, Walden, Debra, Guy, Annette, Nason, Jennifer, Talbot, Morgan, Lee, Kristen, Penny, Sarah, Boles, Terri, Drummond, Melanie, Kohlleppel, Katy, Kathen, Charmaine, Kaletka, Brian, Gonzales, Shania, Worwa, Cathy, Fisher, Molly, Richter, Tyler, Ginder, Alexander, Reich, Brixen, Rau, Carrie, Loertscher, Manndi, Bledsoe, Laura, McGrath, Kandace, Lewis, Kimberlee Weaver, Burnett, Jill, Schaefer, Susan, Bird, Karie, Giblin, Clare, Daly, Rita, Lanier, Kristi, Warden, Kelly, Wassenaar, Jenna, Ericksen, Jensina, Davern, Bridget, Osborne, Mary Pat, Gregorich, Brittany, Talele, Neha, Obregon, Evelyn, Ziyeh, Tiglath, Clarke, Molly, Wegner, Rachel E., Patel, Palak, Schau, Molly, Russow, Annamarie, Curry, Kelly, Sinnamon, Susan, Barnhart, Lisa, Parkinson, Charlamaine, Hanson, Mary, Kuan, Elizabeth, Lacy, Conra Backstrom, Galvis, Edshelee M., Bombino, Susana, Martinez, Denise, Bell, Suzi, Long, Corrie, Longa, Cathy, Westerveld, Michael, McConkey, Stacy, Hay, Anne, Natarajan, Niranjana, Gaudette, Shari, Cobb, Sarah, Sharp, Gregory, Schumacher, Elizabeth, Schuschke, Leslie, Frey, Charlotte, Fierro, Mario, Gilmore, Lois, Lundequam, Pamela, Hoekstra, Ronald, Ketko, Anastasia, Perdue, Nina, Cunningham, Sean, Stout, Kelly, Hall, Becky, Morshedzadeh, Galina, Ostrander, Betsy, Winter, Sarah, Cox, Lauren, Rainaldi, Matthew A., Hensley, Sarah, Morris, Melissa, Roberts, Dia, Tuttle, Melissa, Boys, Christopher, Hultgren, Solveig, Pierpont, Elizabeth I., George, Tom, King, Kelly E., Bataglia, Katherine, Neis, Cathy, Bergeron, Mark, Miller, Cristina, Accomando, Cara, Gavin, Jennifer Anne, Maczek, Elizabeth, Marakovitz, Susan, Knorr, Aimee, Smith, Vincent C., Stewart, Jane E., Weissbourd, Marie, deRegnier, Raye-Ann, Matoba, Nana, Heaton, Shelly C., Cascio, Erika M., Brady, Janet, Ghosh, Suman, Ditto, Jessica, Leppert, Mary, Lowe, Jean, Fuller, Janell, DuPont, Tara, Kloska, Pamela, Patel, Saurabh, Carbonell, Lauren, Patino-Fernandez, Anna Maria, de Lerma, Carmen, McDonough, Kelly, De Cortada, Maiana, Chavis, Lacy, Shannon, Jane, Konodi, Mark A., Nefcy, Christopher, Kuban, Karl C.K., Lowe, Jean R., O'Shea, T. Michael, Dighe, Manjiri, Richards, Todd, Shaw, Dennis W.W., Studholme, Colin, Traudt, Christopher M., Ballard, Roberta, Hartman, Adam, Janis, Scott, Ohls, T. Robin, O'Shea, Michael, Guillet, Ronnie, Ball, M. Bethany, Glass, Hannah, Saville, Ben, Schreiber, Michael, Askenazi, David J., Schmicker, Robert H., Brophy, Patrick, Goldstein, Stuart L., and Hingorani, Sangeeta

Published
2021
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11. The Randomized, Controlled Trial of Late Surfactant: Effects on Respiratory Outcomes at 1-Year Corrected Age

Author

Keller, Roberta L, Eichenwald, Eric C, Hibbs, Anna Maria, Rogers, Elizabeth E, Wai, Katherine C, Black, Dennis M, Ballard, Philip L, Asselin, Jeanette M, Truog, William E, Merrill, Jeffrey D, Mammel, Mark C, Steinhorn, Robin H, Ryan, Rita M, Durand, David J, Bendel, Catherine M, Bendel-Stenzel, Ellen M, Courtney, Sherry E, Dhanireddy, Ramasubbareddy, Hudak, Mark L, Koch, Frances R, Mayock, Dennis E, McKay, Victor J, Helderman, Jennifer, Porta, Nicolas F, Wadhawan, Rajan, Palermo, Lisa, Ballard, Roberta A, and Group, TOLSURF Study

Subjects
Paediatrics, Biomedical and Clinical Sciences, Preterm, Low Birth Weight and Health of the Newborn, Clinical Research, Lung, Pediatric, Perinatal Period - Conditions Originating in Perinatal Period, Clinical Trials and Supportive Activities, 6.1 Pharmaceuticals, Reproductive health and childbirth, Administration, Inhalation, Age Factors, Bronchopulmonary Dysplasia, Confidence Intervals, Dose-Response Relationship, Drug, Double-Blind Method, Drug Administration Schedule, Female, Follow-Up Studies, Gestational Age, Humans, Infant, Infant, Extremely Low Birth Weight, Infant, Newborn, Male, Nitric Oxide, Pulmonary Surfactants, Respiration, Artificial, Respiratory Distress Syndrome, Newborn, Risk Assessment, Survival Rate, Time Factors, TOLSURF Study Group, bronchopulmonary dysplasia, prematurity, pulmonary morbidity, wheeze, Human Movement and Sports Sciences, Paediatrics and Reproductive Medicine, Pediatrics
Abstract

ObjectiveTo determine the effects of late surfactant on respiratory outcomes determined at 1-year corrected age in the Trial of Late Surfactant (TOLSURF), which randomized newborns of extremely low gestational age (≤28 weeks' gestational age) ventilated at 7-14 days to late surfactant and inhaled nitric oxide vs inhaled nitric oxide-alone (control).Study designCaregivers were surveyed in a double-blinded manner at 3, 6, 9, and 12 months' corrected age to collect information on respiratory resource use (infant medication use, home support, and hospitalization). Infants were classified for composite outcomes of pulmonary morbidity (no PM, determined in infants with no reported respiratory resource use) and persistent PM (determined in infants with any resource use in ≥3 surveys).ResultsInfants (n = 450, late surfactant n = 217, control n = 233) were 25.3 ± 1.2 weeks' gestation and 713 ± 164 g at birth. In the late surfactant group, fewer infants received home respiratory support than in the control group (35.8% vs 52.9%, relative benefit [RB] 1.28 [95% CI 1.07-1.55]). There was no benefit of late surfactant for No PM vs PM (RB 1.27; 95% CI 0.89-1.81) or no persistent PM vs persistent PM (RB 1.01; 95% CI 0.87-1.17). After adjustment for imbalances in baseline characteristics, relative benefit of late surfactant treatment increased: RB 1.40 (95% CI 0.89-1.80) for no PM and RB 1.24 (95% CI 1.08-1.42) for no persistent PM.ConclusionTreatment of newborns of extremely low gestational age with late surfactant in combination with inhaled nitric oxide decreased use of home respiratory support and may decrease persistent pulmonary morbidity.Trial registrationClinicalTrials.gov: NCT01022580.

Published
2017

12. Treatment of pulmonary hypertension during initial hospitalization in a multicenter cohort of infants with congenital diaphragmatic hernia (CDH)

Author

Seabrook, Ruth B., Grover, Theresa R., Rintoul, Natalie, Weems, Mark, Keene, Sarah, Brozanski, Beverly, DiGeronimo, Robert, Haberman, Beth, Hedrick, Holly, Gien, Jason, Ali, Noorjahan, Chapman, Rachel, Daniel, John, Harrison, H. Allen, Johnson, Yvette, Porta, Nicolas F. M., Uhing, Michael, Zaniletti, Isabella, and Murthy, Karna

Published
2021
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13. Randomized Trial of Late Surfactant Treatment in Ventilated Preterm Infants Receiving Inhaled Nitric Oxide

Author

Ballard, Roberta A, Keller, Roberta L, Black, Dennis M, Ballard, Philip L, Merrill, Jeffrey D, Eichenwald, Eric C, Truog, William E, Mammel, Mark C, Steinhorn, Robin H, Rogers, Elizabeth E, Ryan, Rita M, Durand, David J, Asselin, Jeanette M, Bendel, Catherine M, Bendel-Stenzel, Ellen M, Courtney, Sherry E, Dhanireddy, Ramasubbareddy, Hudak, Mark L, Koch, Frances R, Mayock, Dennis E, McKay, Victor J, O'Shea, T Michael, Porta, Nicolas F, Wadhawan, Rajan, Palermo, Lisa, Strong, S Hamilton, Immamura-Ching, J, Orfanos-Villalobos, M, Williams, C, Horton, D, Pacello, L, Willard, A, Gauldin, C, Holmes, A, Johnson, P, Meinert, K, Reynolds, AM, Lucie, J, Conway, P, Sacilowski, ML, Leadersdorff, M, Orbank, P, Wynn, K, deUngria, M, Khan, J, Hamann, K, Schau, M, Hopkins, B, Jenson, J, Garcia, C, Shariff, J, McGovern, R, Adelman, J, Combs, A, Tjersland, M, Walker, S, Howland, E, Longoria, J, Meo, H, McDavid, G, Burson, K, Hinojosa, R, Johnson, C, Miller, K, Rogers, S, Wright, S, Barnette, K, Kellum, A, Burke, M, Hayes, C, Chadwick, S, Howard, D, Kennedy, C, Prince, R, Stefanescu, B, Helderman, J, Warden, K, Brown, P, Griffin, J, Conley, L, Georgieff, M, Davern, B, Mills, M, Ritter, S, Wagner, C, Fanning, D, Roberson, J, Lampland, A, Meyers, P, Brey, A, Worwa, C, Dixon, P, Ebert, G, Hejl, C, Maxwell, M, McCullough, K, Abiad, MT El, Talati, A, Dempsey, S, and Gammage, K

Subjects
Paediatrics, Biomedical and Clinical Sciences, Pediatric, Preterm, Low Birth Weight and Health of the Newborn, Lung, Neonatal Respiratory Distress, Patient Safety, Clinical Research, Perinatal Period - Conditions Originating in Perinatal Period, Clinical Trials and Supportive Activities, Reproductive health and childbirth, Administration, Inhalation, Bronchopulmonary Dysplasia, Female, Humans, Infant, Newborn, Infant, Premature, Infant, Premature, Diseases, Infant, Very Low Birth Weight, Male, Nitric Oxide, Pulmonary Surfactants, Respiration, Artificial, Survival Rate, United States, TOLSURF Study Group, Human Movement and Sports Sciences, Paediatrics and Reproductive Medicine, Pediatrics
Abstract

ObjectiveTo assess whether late surfactant treatment in extremely low gestational age (GA) newborn infants requiring ventilation at 7-14 days, who often have surfactant deficiency and dysfunction, safely improves survival without bronchopulmonary dysplasia (BPD).Study designExtremely low GA newborn infants (GA ≤28 0/7 weeks) who required mechanical ventilation at 7-14 days were enrolled in a randomized, masked controlled trial at 25 US centers. All infants received inhaled nitric oxide and either surfactant (calfactant/Infasurf) or sham instillation every 1-3 days to a maximum of 5 doses while intubated. The primary outcome was survival at 36 weeks postmenstrual age (PMA) without BPD, as evaluated by physiological oxygen/flow reduction.ResultsA total of 511 infants were enrolled between January 2010 and September 2013. There were no differences between the treated and control groups in mean birth weight (701 ± 164 g), GA (25.2 ± 1.2 weeks), percentage born at GA

Published
2016

14. The Impact of Pulmonary Hypertension in Preterm Infants with Severe Bronchopulmonary Dysplasia through 1 Year

Author

Lagatta, Joanne M., Hysinger, Erik B., Zaniletti, Isabella, Wymore, Erica M., Vyas-Read, Shilpa, Yallapragada, Sushmita, Nelin, Leif D., Truog, William E., Padula, Michael A., Porta, Nicolas F.M., Savani, Rashmin C., Potoka, Karin P., Kawut, Steven M., DiGeronimo, Robert, Natarajan, Girija, Zhang, Huayan, Grover, Theresa R., Engle, William A., and Murthy, Karna

Published
2018
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15. Predicting Risk of Infection in Infants with Congenital Diaphragmatic Hernia

Author

Asselin, Jeanette, Durand, David, Dykes, Francine, Evans, Jacquelyn, Murthy, Karna, Padula, Michael, Pallotto, Eugenia, Grover, Theresa, Brozanski, Beverly, Piazza, Anthony, Reber, Kristina, Short, Billie, Porta, Nicolas F.M., Pallotto, Eugenia K., Rintoul, Natalie, Keene, Sarah, Chicoine, Louis, Gien, Jason, Brozanski, Beverly S., Johnson, Yvette R., Haberman, Beth, DiGeronimo, Robert, Zaniletti, Isabella, and Grover, Theresa R.

Published
2018
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16. Enteral Feeding during Indomethacin and Ibuprofen Treatment of a Patent Ductus Arteriosus

Author

Clyman, Ronald, Wickremasinghe, Andrea, Jhaveri, Nami, Hassinger, Denise C, Attridge, Joshua T, Sanocka, Ulana, Polin, Richard, Gillam-Krakauer, Maria, Reese, Jeff, Mammel, Mark, Couser, Robert, Mulrooney, Neil, Yanowitz, Toby D, Derrick, Matthew, Jegatheesan, Priya, Walsh, Michele, Fujii, Alan, Porta, Nicolas, Carey, William A, Swanson, Jonathan R, and Investigators, Ductus Arteriosus Feed or Fast with Indomethacin or Ibuprofen

Subjects
Preterm, Low Birth Weight and Health of the Newborn, Clinical Research, Infant Mortality, Perinatal Period - Conditions Originating in Perinatal Period, Clinical Trials and Supportive Activities, Nutrition, Pediatric, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Reproductive health and childbirth, Combined Modality Therapy, Ductus Arteriosus, Patent, Enteral Nutrition, Female, Humans, Ibuprofen, Indomethacin, Infant, Newborn, Male, Prospective Studies, Time Factors, Ductus Arteriosus Feed or Fast with Indomethacin or Ibuprofen (DAFFII) Investigators, BPD, Bronchopulmonary dysplasia, NEC, Necrotizing enterocolitis, Nil per os, PDA, Patent ductus arteriosus, npo, Human Movement and Sports Sciences, Paediatrics and Reproductive Medicine, Pediatrics
Abstract

ObjectiveTo test the hypothesis that infants who are just being introduced to enteral feedings will advance to full enteral nutrition at a faster rate if they receive "trophic" (15 mL/kg/d) enteral feedings while receiving indomethacin or ibuprofen treatment for patent ductus arteriosus.Study designInfants were eligible for the study if they were 23(1/7)-30(6/7) weeks' gestation, weighed 401-1250 g at birth, received maximum enteral volumes ≤60 mL/kg/d, and were about to be treated with indomethacin or ibuprofen. A standardized "feeding advance regimen" and guidelines for managing feeding intolerance were followed at each site (N = 13).ResultsInfants (N = 177, 26.3 ± 1.9 weeks' mean ± SD gestation) were randomized at 6.5 ± 3.9 days to receive "trophic" feeds ("feeding" group, n = 81: indomethacin 80%, ibuprofen 20%) or no feeds ("fasting [nil per os]" group, n = 96: indomethacin 75%, ibuprofen 25%) during the drug administration period. Maximum daily enteral volumes before study entry were 14 ± 15 mL/kg/d. After drug treatment, infants randomized to the "feeding" arm required fewer days to reach the study's feeding volume end point (120 mL/kg/d). Although the enteral feeding end point was reached at an earlier postnatal age, the age at which central venous lines were removed did not differ between the 2 groups. There were no differences between the 2 groups in the incidence of infection, necrotizing enterocolitis, spontaneous intestinal perforation, or other neonatal morbidities.ConclusionInfants required less time to reach the feeding volume end point if they were given "trophic" enteral feedings when they received indomethacin or ibuprofen treatments.

Published
2013

17. Extracorporeal membrane oxygenation and bloodstream infection in congenital diaphragmatic hernia

Author

Keene, Sarah, Grover, Theresa R., Murthy, Karna, Pallotto, Eugenia K., Brozanski, Beverly, Gien, Jason, Zaniletti, Isabella, Johnson, Yvette R., Seabrook, Ruth B., Porta, Nicolas F. M., Haberman, Beth, DiGeronimo, Robert, Rintoul, Natalie, and on behalf of the Children’s Hospitals Neonatal Consortium’s (CHNC) Congenital Diaphragmatic Hernia Focus Group

Published
2019
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21. The Randomized, Controlled Trial of Late Surfactant: Effects on Respiratory Outcomes at 1-Year Corrected Age

Author

Keller, Roberta L., Eichenwald, Eric C., Hibbs, Anna Maria, Rogers, Elizabeth E., Wai, Katherine C., Black, Dennis M., Ballard, Philip L., Asselin, Jeanette M., Truog, William E., Merrill, Jeffrey D., Mammel, Mark C., Steinhorn, Robin H., Ryan, Rita M., Durand, David J., Bendel, Catherine M., Bendel-Stenzel, Ellen M., Courtney, Sherry E., Dhanireddy, Ramasubbareddy, Hudak, Mark L., Koch, Frances R., Mayock, Dennis E., McKay, Victor J., Helderman, Jennifer, Porta, Nicolas F., Wadhawan, Rajan, Palermo, Lisa, and Ballard, Roberta A.

Published
2017
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22. Randomized Trial of Late Surfactant Treatment in Ventilated Preterm Infants Receiving Inhaled Nitric Oxide

Author

Strong, S. Hamilton, Immamura-Ching, J., Orfanos-Villalobos, M., Williams, C., Horton, D., Pacello, L., Willard, A., Gauldin, C., Holmes, A., Johnson, P., Meinert, K., Reynolds, A.M., Lucie, J., Conway, P., Sacilowski, M.l., Leadersdorff, M., Orbank, P., Wynn, K., deUngria, M., Khan, J., Hamann, K., Schau, M., Hopkins, B., Jenson, J., Garcia, C., Shariff, J., McGovern, R., Adelman, J., Combs, A., Tjersland, M., Walker, S., Howland, E., Longoria, J., Meo, H., McDavid, G., Burson, K., Hinojosa, R., Johnson, C., Miller, K., Rogers, S., Wright, S., Barnette, K., Kellum, A., Burke, M., Hayes, C., Chadwick, S., Howard, D., Kennedy, C., Prince, R., Stefanescu, B., Helderman, J., Warden, K., Brown, P., Griffin, J., Conley, L., Georgieff, M., Davern, B., Mills, M., Ritter, S., Wagner, C., Fanning, D., Roberson, J., Lampland, A., Meyers, P., Brey, A., Worwa, C., Dixon, P., Ebert, G., Hejl, C., Maxwell, M., McCullough, K., El Abiad, M.T., Talati, A., Dempsey, S., Gammage, K., Gower, G., James, K., LeNoue, P., Bell, S., Bruton, D., Beaulieu, M., Williams, R., Barron-Nelson, R., Taylor, S., Sikes, N.C., Lowe, G., Proffitt, B., Chapin, C., Horneman, H., Kelley, S., Vittinghoff, E., Hietpas, J., Denton, L., Wu, L., Jobe, A., Fanaroff, A., Clemons, T., Glantz, L., Reboussin, D., Van Meurs, K., Allen, M., Vohr, B., Ballard, R., Ballard, P., Blaisdell, C., Durand, D., Black, D., Eichenwald, E., Keller, R., Mammel, M., Merrill, J., Rogers, E., Ryan, R., Truog, W., Asselin, J., Newton, N., Ballard, Roberta A., Keller, Roberta L., Black, Dennis M., Ballard, Philip L., Merrill, Jeffrey D., Eichenwald, Eric C., Truog, William E., Mammel, Mark C., Steinhorn, Robin H., Rogers, Elizabeth E., Ryan, Rita M., Durand, David J., Asselin, Jeanette M., Bendel, Catherine M., Bendel-Stenzel, Ellen M., Courtney, Sherry E., Dhanireddy, Ramasubbareddy, Hudak, Mark L., Koch, Frances R., Mayock, Dennis E., McKay, Victor J., O'Shea, T. Michael, Porta, Nicolas F., Wadhawan, Rajan, and Palermo, Lisa

Published
2016
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23. Variability for age at successful extubation in infants with congenital diaphragmatic hernia

Author

Porta, Nicolas F.M., primary, Naing, Khatija, additional, Keene, Sarah, additional, Grover, Theresa R., additional, Hedrick, Holly, additional, Mahmood, Burhan, additional, Seabrook, Ruth, additional, Daniel IV, John, additional, Harrison, Allen, additional, Weems, Mark F., additional, Yoder, Bradley A., additional, DiGeronimo, Robert, additional, Haberman, Beth, additional, Dariya, Vedanta, additional, Guner, Yigit, additional, Rintoul, Natalie E., additional, and Murthy, Karna, additional

Published
2022
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24. Experiences on Using Software Experiments in the Validation of Industrial Research Questions

Author

Gessenharter, Dominik, Merten, Alexander-Marc, Raschke, Alexander, Porta, Nicolas Fernando, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Cuadrado-Gallego, Juan J., editor, Braungarten, René, editor, Dumke, Reiner R., editor, and Abran, Alain, editor

Published
2008
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25. Association between Term Equivalent Brain Magnetic Resonance Imaging and 2-Year Outcomes in Extremely Preterm Infants: A Report from the Preterm Erythropoietin Neuroprotection Trial Cohort

Author

Mayock, Dennis E., primary, Gogcu, Semsa, additional, Puia-Dumitrescu, Mihai, additional, Shaw, Dennis W.W., additional, Wright, Jason N., additional, Comstock, Bryan A., additional, Heagerty, Patrick J., additional, Juul, Sandra E., additional, Wadhawan, Rajan, additional, Courtney, Sherry E., additional, Robinson, Tonya, additional, Ahmad, Kaashif A., additional, Bendel-Stenzel, Ellen, additional, Baserga, Mariana, additional, LaGamma, Edmund F., additional, Downey, L. Corbin, additional, Rao, Raghavendra, additional, Fahim, Nancy, additional, Lampland, Andrea, additional, Frantz, Ivan D., additional, Khan, Janine, additional, Weiss, Michael, additional, Gilmore, Maureen M., additional, Ohls, Robin K., additional, Lowe, Jean, additional, Srinivasan, Nishant, additional, Perez, Jorge E., additional, McKay, Victor, additional, Thomas, Billy, additional, Elhassan, Nahed, additional, Mulkey, Sarah, additional, Vijayamadhavan, Vivek K., additional, Mulrooney, Neil, additional, Yoder, Bradley, additional, Kase, Jordan S., additional, Check, Jennifer, additional, Osterholm, Erin, additional, George, Thomas, additional, Georgieff, Michael, additional, Martin, Camilia R., additional, O'Reilly, Deirdre, additional, deRegnier, Raye-Ann, additional, Porta, Nicolas, additional, Bazacliu, Catalina, additional, Northington, Frances, additional, Valdez, Raul Chavez, additional, Saurabhkumar, Patel, additional, Diaz-Barbosa, Magaly, additional, Richards, Todd, additional, Feltner, John B., additional, Esposito, Isabella, additional, Hauge, Stephanie, additional, Nikirk, Samantha, additional, Silvia, Amy, additional, Clopp, Bailey, additional, Ott, Debbie, additional, Mora, Ariana Franco, additional, Hedrick, Pamela, additional, Flynn, Vicki, additional, Wyatt, Andrea, additional, Loy, Emilie, additional, Sikes, Natalie, additional, Mason, Melanie, additional, McConnell, Jana, additional, Brown, Tiffany, additional, Harrison, Henry, additional, Pearson, Denise, additional, Drake, Tammy, additional, Wright, Jocelyn, additional, Walden, Debra, additional, Guy, Annette, additional, Nason, Jennifer, additional, Talbot, Morgan, additional, Lee, Kristen, additional, Penny, Sarah, additional, Boles, Terri, additional, Drummond, Melanie, additional, Kohlleppel, Katy, additional, Kathen, Charmaine, additional, Kaletka, Brian, additional, Gonzales, Shania, additional, Worwa, Cathy, additional, Fisher, Molly, additional, Richter, Tyler, additional, Ginder, Alexander, additional, Reich, Brixen, additional, Rau, Carrie, additional, Loertscher, Manndi, additional, Cole, Laura, additional, McGrath, Kandace, additional, Lewis, Kimberlee Weaver, additional, Burnett, Jill, additional, Schaefer, Susan, additional, Bird, Karie, additional, Giblin, Clare, additional, Daly, Rita, additional, Lanier, Kristi, additional, Warden, Kelly, additional, Wassenaar, Jenna, additional, Ericksen, Jensina, additional, Davern, Bridget, additional, Osborne, Mary Pat, additional, Talele, Neha, additional, Obregon, Evelyn, additional, Ziyeh, Tiglath, additional, Clarke, Molly, additional, Wegner, Rachel E., additional, Patel, Palak, additional, Schau, Molly, additional, Russow, Annamarie, additional, Curry, Kelly, additional, Barnhart, Lisa, additional, Parkinson, Charlamaine, additional, Beauman, Sandra, additional, Hanson, Mary, additional, Kuan, Elizabeth, additional, Lacy, Conra Backstrom, additional, Galvis, Edshelee M., additional, Bombino, Susana, additional, Martinez, Denise, additional, Bell, Suzi, additional, Long, Corrie, additional, Nefcy, Christopher, additional, Konodi, Mark A., additional, Vu, Phuong T., additional, Hartman, Adam, additional, O'Shea, T. Michael, additional, Ballard, Roberta, additional, O'Shea, Mike, additional, Kuban, Karl, additional, and Widness, John, additional

Published
2021
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27. A comparison of newer classifications of bronchopulmonary dysplasia: findings from the Children’s Hospitals Neonatal Consortium Severe BPD Group

Author

Vyas-Read, Shilpa, primary, Logan, J. Wells, additional, Cuna, Alain C., additional, Machry, Joana, additional, Leeman, Kristin T., additional, Rose, Rebecca S., additional, Mikhael, Michel, additional, Wymore, Erica, additional, Ibrahim, John W., additional, DiGeronimo, Robert J., additional, Yallapragada, Sushmita, additional, Haberman, Beth E., additional, Padula, Michael A., additional, Porta, Nicolas F., additional, Murthy, Karna, additional, Nelin, Leif D., additional, Coghill, Carl H., additional, Zaniletti, Isabella, additional, Savani, Rashmin C., additional, Truog, William, additional, Engle, William A., additional, and Lagatta, Joanne M., additional

Published
2021
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28. Randomized Trial of Late Surfactant Treatment in Ventilated Preterm Infants Receiving Inhaled Nitric Oxide

Author

Ballard, Roberta A., Keller, Roberta L., Black, Dennis M., Ballard, Philip L., Merrill, Jeffrey D., Eichenwald, Eric C., Truog, William E., Mammel, Mark C., Steinhorn, Robin H., Rogers, Elizabeth E., Ryan, Rita M., Durand, David J., Asselin, Jeanette M., Bendel, Catherine M., Bendel-Stenzel, Ellen M., Courtney, Sherry E., Dhanireddy, Ramasubbareddy, Hudak, Mark L., Koch, Frances R., Mayock, Dennis E., McKay, Victor J., OʼShea, Michael T., Porta, Nicolas F., Wadhawan, Rajan, Palermo, Lisa, Strong, Hamilton S., Immamura-Ching, J., Orfanos-Villalobos, M., Williams, C., Horton, D., Pacello, L., Willard, A., Gauldin, C., Holmes, A., Johnson, P., Meinert, K., Reynolds, A. M., Lucie, J., Conway, P., Sacilowski, M., Leadersdorff, M., Orbank, P., Wynn, K., deUngria, M., Khan, J., Hamann, K., Schau, M., Hopkins, B., Jenson, J., Garcia, C., Shariff, J., McGovern, R., Adelman, J., Combs, A., Tjersland, M., Walker, S., Howland, E., Longoria, J., Meo, H., McDavid, G., Burson, K., Hinojosa, R., Johnson, C., Miller, K., Rogers, S., Wright, S., Barnette, K., Kellum, A., Burke, M., Hayes, C., Chadwick, S., Howard, D., Kennedy, C., Prince, R., Stefanescu, B., Helderman, J., Warden, K., Brown, P., Griffin, J., Conley, L., Georgieff, M., Davern, B., Mills, M., Ritter, S., Wagner, C., Fanning, D., Roberson, J., Lampland, A., Meyers, P., Brey, A., Worwa, C., Dixon, P., Ebert, G., Hejl, C., Maxwell, M., McCullough, K., El Abiad, M. T., Talati, A., Dempsey, S., Gammage, K., Gower, G., James, K., LeNoue, P., Bell, S., Bruton, D., Beaulieu, M., Williams, R., Barron-Nelson, R., Taylor, S., Sikes, N. C., Lowe, G., Proffitt, B., Chapin, C., Horneman, H., Kelley, S., Vittinghoff, E., Hietpas, J., Denton, L., Wu, L., Jobe, A., Fanaroff, A., Clemons, T., Glantz, L., Reboussin, D., Van Meurs, K., Allen, M., Vohr, B., Ballard, R., Ballard, P., Blaisdell, C., Durand, D., Black, D., Eichenwald, E., Keller, R., Mammel, M., Merrill, J., Rogers, E., Ryan, R., Truog, W., Asselin, J., and Newton, N.

Published
2016
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29. Differential patterns of 27 cord blood immune biomarkers across gestational age

Author

Matoba, Nana, Yu, Yunxian, Mestan, Karen, Pearson, Colleen, Ortiz, Katherin, Porta, Nicolas, Thorsen, Poul, Skogstrand, Kristin, Hougaard, David M., Zuckerman, Barry, and Wang, Xiaobin

Subjects
Inflammation -- Complications and side effects, Biological markers -- Usage, Gestational age -- Health aspects, Infants (Premature) -- Research, Infants (Premature) -- Health aspects, Infants (Newborn) -- Diseases, Infants (Newborn) -- Risk factors
Published
2009

30. The Impact of Erythropoietin on Short- and Long-Term Kidney-Related Outcomes in Neonates of Extremely Low Gestational Age. Results of a Multicenter, Double-Blind, Placebo-Controlled Randomized Clinical Trial

Author

Askenazi, David J., primary, Heagerty, Patrick J., additional, Schmicker, Robert H., additional, Brophy, Patrick, additional, Juul, Sandra E., additional, Goldstein, Stuart L., additional, Hingorani, Sangeeta, additional, Comstock, Bryan A., additional, Wadhawan, Rajan, additional, Mayock, Dennis E., additional, Courtney, Sherry E., additional, Robinson, Tonya, additional, Ahmad, Kaashif A., additional, Bendel-Stenzel, Ellen, additional, Baserga, Mariana, additional, LaGamma, Edmund F., additional, Downey, L. Corbin, additional, Rao, Raghavendra, additional, Fahim, Nancy, additional, Lampland, Andrea, additional, Frantz, Ivan D., additional, Khan, Janine Y., additional, Weiss, Michael, additional, Gilmore, Maureen M., additional, Ohls, Robin, additional, Srinivasan, Nishant, additional, Perez, Jorge E., additional, McKay, Victor, additional, Vu, Phuong T., additional, Thomas, Billy, additional, Elhassan, Nahed, additional, Mulkey, Sarah, additional, Dydynski, Philip, additional, Vijayamadhavan, Vivek K., additional, Mulrooney, Neil, additional, Yoder, Bradley, additional, Kase, Jordan S., additional, Check, Jennifer, additional, Gogcu, Semsa, additional, Osterholm, Erin, additional, Ramel, Sara, additional, Bendel, Catherine, additional, Gale, Cheryl, additional, George, Thomas, additional, Georgieff, Michael, additional, Gisslen, Tate, additional, Guiang, Sixto, additional, Hall, Anne, additional, Johnson, Dana, additional, Pfister, Katie, additional, Podgorski, Heather, additional, Roberts, Kari, additional, Stepka, Erin, additional, Engel, Melissa, additional, Kamrath, Heidi, additional, Scheurer, Johannah, additional, Hanson, Angela, additional, Satrom, Katherine, additional, Pfister, Susan, additional, Simones, Ann, additional, Plummer, Erin, additional, Zorn, Elizabeth, additional, Martin, Camilia R., additional, O'Reilly, Deirdre, additional, Porta, Nicolas, additional, Bazacliu, Catalina, additional, Williams, Jonathan, additional, Rajderkar, Dhanashree, additional, Northington, Frances, additional, Valdez, Raul Chavez, additional, Beauman, Sandra, additional, Saurabhkumar, Patel, additional, Diaz-Barbosa, Magaly, additional, Serize, Arturo, additional, Jordan, Jorge, additional, Ott, Debbie, additional, Mora, Ariana Franco, additional, Hedrick, Pamela, additional, Flynn, Vicki, additional, Silvia, Amy, additional, Clopp, Bailey, additional, Feltner, John B., additional, Esposito, Isabella, additional, Hauge, Stephanie, additional, Nikirk, Samantha, additional, Purnell, Andrea, additional, Loy, Emilie, additional, Sikes, Natalie, additional, Mason, Melanie, additional, McConnell, Jana, additional, Brown, Tiffany, additional, Harrison, Henry, additional, Pearson, Denise, additional, Drake, Tammy, additional, Wright, Jocelyn, additional, Walden, Debra, additional, Guy, Annette, additional, Nason, Jennifer, additional, Talbot, Morgan, additional, Lee, Kristen, additional, Penny, Sarah, additional, Boles, Terri, additional, Drummond, Melanie, additional, Kohlleppel, Katy, additional, Kathen, Charmaine, additional, Kaletka, Brian, additional, Gonzales, Shania, additional, Worwa, Cathy, additional, Fisher, Molly, additional, Richter, Tyler, additional, Ginder, Alexander, additional, Reich, Brixen, additional, Rau, Carrie, additional, Loertscher, Manndi, additional, Bledsoe, Laura, additional, McGrath, Kandace, additional, Lewis, Kimberlee Weaver, additional, Burnett, Jill, additional, Schaefer, Susan, additional, Bird, Karie, additional, Giblin, Clare, additional, Daly, Rita, additional, Lanier, Kristi, additional, Warden, Kelly, additional, Wassenaar, Jenna, additional, Ericksen, Jensina, additional, Davern, Bridget, additional, Osborne, Mary Pat, additional, Gregorich, Brittany, additional, Talele, Neha, additional, Obregon, Evelyn, additional, Ziyeh, Tiglath, additional, Clarke, Molly, additional, Wegner, Rachel E., additional, Patel, Palak, additional, Schau, Molly, additional, Russow, Annamarie, additional, Curry, Kelly, additional, Sinnamon, Susan, additional, Barnhart, Lisa, additional, Parkinson, Charlamaine, additional, Hanson, Mary, additional, Kuan, Elizabeth, additional, Lacy, Conra Backstrom, additional, Galvis, Edshelee M., additional, Bombino, Susana, additional, Martinez, Denise, additional, Bell, Suzi, additional, Long, Corrie, additional, Longa, Cathy, additional, Westerveld, Michael, additional, McConkey, Stacy, additional, Hay, Anne, additional, Natarajan, Niranjana, additional, Gaudette, Shari, additional, Cobb, Sarah, additional, Sharp, Gregory, additional, Schumacher, Elizabeth, additional, Schuschke, Leslie, additional, Frey, Charlotte, additional, Fierro, Mario, additional, Gilmore, Lois, additional, Lundequam, Pamela, additional, Hoekstra, Ronald, additional, Ketko, Anastasia, additional, Perdue, Nina, additional, Cunningham, Sean, additional, Stout, Kelly, additional, Hall, Becky, additional, Morshedzadeh, Galina, additional, Ostrander, Betsy, additional, Winter, Sarah, additional, Cox, Lauren, additional, Rainaldi, Matthew A., additional, Hensley, Sarah, additional, Morris, Melissa, additional, Roberts, Dia, additional, Tuttle, Melissa, additional, Boys, Christopher, additional, Hultgren, Solveig, additional, Pierpont, Elizabeth I., additional, George, Tom, additional, King, Kelly E., additional, Bataglia, Katherine, additional, Neis, Cathy, additional, Bergeron, Mark, additional, Miller, Cristina, additional, Accomando, Cara, additional, Gavin, Jennifer Anne, additional, Maczek, Elizabeth, additional, Marakovitz, Susan, additional, Knorr, Aimee, additional, Smith, Vincent C., additional, Stewart, Jane E., additional, Weissbourd, Marie, additional, deRegnier, Raye-Ann, additional, Matoba, Nana, additional, Heaton, Shelly C., additional, Cascio, Erika M., additional, Brady, Janet, additional, Ghosh, Suman, additional, Ditto, Jessica, additional, Leppert, Mary, additional, Lowe, Jean, additional, Fuller, Janell, additional, DuPont, Tara, additional, Kloska, Pamela, additional, Patel, Saurabh, additional, Carbonell, Lauren, additional, Patino-Fernandez, Anna Maria, additional, de Lerma, Carmen, additional, McDonough, Kelly, additional, De Cortada, Maiana, additional, Chavis, Lacy, additional, Shannon, Jane, additional, Konodi, Mark A., additional, Nefcy, Christopher, additional, Kuban, Karl C.K., additional, Lowe, Jean R., additional, O'Shea, T. Michael, additional, Dighe, Manjiri, additional, Richards, Todd, additional, Shaw, Dennis W.W., additional, Studholme, Colin, additional, Traudt, Christopher M., additional, Ballard, Roberta, additional, Hartman, Adam, additional, Janis, Scott, additional, Ohls, T. Robin, additional, O'Shea, Michael, additional, Guillet, Ronnie, additional, Ball, M. Bethany, additional, Glass, Hannah, additional, Saville, Ben, additional, and Schreiber, Michael, additional

Published
2021
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33. Pre- and Postnatal Lung Development, Maturation, and Plasticity; Distal air space epithelial fluid clearance in near-term rat fetuses is fast and requires endogenous catecholamines

Author

Folkesson, Hans G., Matthay, Michael A., Chapin, Cheryl J., Porta, Nicolas F. M., and Kitterman, Joseph A.

Subjects
Physiology -- Research, Amiloride -- Research, Epinephrine -- Research, Pulmonary edema -- Research, Infants (Newborn) -- Health aspects, Biological sciences
Abstract

Knowledge about the conversion of the epithelium in the distal air spaces of the lung from secretion to absorption is imperative to the understanding of postnatal lung development; little such information is available in rats. Distal air space fluid clearance was therefore measured in 21- to 22-day gestation rat fetuses and newborn (40 h) rats. Distal air space fluid clearance was measured from the increase in [sup.131]I-albumin concentration in an isosmolar, physiological solution instilled into the developing lungs. There was no net fluid movement across the distal air space epithelium in the lungs of 21-day gestation fetuses. Twenty-four hours later, distal air space fluid was cleared at a rapid rate in the 22-day gestation fetuses. Within the first 40 h after birth, the rate rapidly declined to adult levels. The high distal air space fluid clearance at 22 days gestation and at 40 h after birth was mediated by [beta]-adrenergic receptors as demonstrated by elevated plasma epinephrine levels and inhibition by propranolol. Interestingly, the elevated distal air space fluid clearance in the 22-day gestation fetuses was only minimally amiloride sensitive; however, amiloride sensitivity increased over the first 40 h after birth. In conclusion, these studies demonstrate that 1) rapid rates of net alveolar fluid clearance occur late in gestation in the rat and 2) this clearance is driven by elevations of endogenous epinephrine. amiloride sensitivity; development; distal air space epithelium; epinephrine; [Na.sup.+] transport; pulmonary edema; neonatal respiratory distress syndrome

Published
2002

34. Pre- and Postnatal Lung Development, Maturation, and Plasticity; Effects of oligohydramnios on lung growth and maturation in the fetal rat

Author

Kitterman, Joseph A., Chapin, Cheryl J., Vanderbilt, Jeff N., Porta, Nicolas F.M., Scavo, Louis M., Dobbs, Leland G., Ertsey, Robert, and Goerke, Jon

Subjects
Physiology -- Research, Kidneys -- Physiological aspects, Oligohydramnios -- Physiological aspects, Lungs -- Physiological aspects, Developmental biology -- Physiological aspects, Rats -- Physiological aspects, Epithelium -- Physiological aspects, Cell differentiation -- Physiological aspects, Pulmonary surfactant -- Physiological aspects, Biological sciences
Abstract

Oligohydramnios (OH) retards fetal lung growth by producing less lung distension than normal. To examine effects of decreased distension on fetal lung development, we produced OH in rats by puncture of uterus and fetal membranes at 16 days of gestation; fetuses were delivered at 21 or 22 days of gestation. Controls were position-matched littermates in the opposite uterine horn. OH lungs had lower weights and less DNA, protein, and water, but no differences in saturated phosphatidylcholine, surfactant proteins (SP)-A and -B, and mRNA for SP-A, -B, -C, and -D. To evaluate effects on epithelial differentiation, we used RT[I.sub.40] and RTI[I.sub.70], proteins specific in lung to luminal surfaces of alveolar type I and II cells, respectively. At 22 days of gestation, OH lungs had less RT[I.sub.40] mRNA (P < 0.05) and protein (P < 0.001), but RTI[I.sub.70] did not differ from controls. With OH, type I cells (in proportion to type II cells) covered less distal air space perimeter (P < 0.01). We conclude that OH, which retards lung growth, has little effect on surfactant and impedes formation of type I cells relative to type II cells. fetal lung development; lung distension; pulmonary epithelial differentiation; pulmonary hypoplasia; pulmonary surfactant

Published
2002

35. Prevalence and Risk Factors for Kidney Disease and Elevated BP in 2-Year-Old Children Born Extremely Premature

Author

Hingorani, Sangeeta, Schmicker, Robert, Ahmad, Kaashif A., Frantz, Ivan D., Mayock, Dennis E., La Gamma, Edmund F., Baserga, Mariana, Khan, Janine Y., Gilmore, Maureen M., Robinson, Tonya, Brophy, Patrick, Heagerty, Patrick J., Juul, Sandra E., Goldstein, Stuart, Askenazi, David, Wadhawan, Rajan, Courtney, Sherry E., Robinson, Tonya, Ahmad, Kaashif A., Bendel-Stenzel, Ellen, Baserga, Mariana, LaGamma, Edmund F., Downey, L. Corbin, Rao, Raghavendra, Fahim, Nancy, Lampland, Andrea, Frantz, Ivan D., Khan, Janine, Weiss, Michael, Gilmore, Maureen M., Ohls, Robin K., Lowe, Jean, Srinivasan, Nishant, Perez, Jorge E., Thomas, Victor McKay Billy, Elhassan, Nahed, Mulkey, Sarah, Vijayamadhavan, Vivek K., Mulrooney, Neil, Yoder, Bradley, Kase, Jordan S., Check, Jennifer, Osterholm, Erin, George, Thomas, Georgieff, Michael, Martin, Camilia R., O?Reilly, Deirdre, deRegnier, Raye-Ann, Porta, Nicolas, Bazacliu, Catalina, Northington, Frances, Valdez, Raul Chavez, Saurabhkumar, Patel, Diaz-Barbosa, Magaly, Richards, Todd, Feltner, John B., Esposito, Isabella, Hauge, Stephanie, Nikirk, Samantha, Silvia, Amy, Clopp, Bailey, Ott, Debbie, Mora, Ariana Franco, Hedrick, Pamela, Flynn, Vicki, Wyatt, Andrea, Loy, Emilie, Sikes, Natalie, Mason, Melanie, McConnell, Jana, Brown, Tiffany, Harrison, Henry, Pearson, Denise, Drake, Tammy, Wright, Jocelyn, Walden, Debra, Guy, Annette, Nason, Jennifer, Talbot, Morgan, Lee, Kristen, Penny, Sarah, Boles, Terri, Drummond, Melanie, Kohlleppel, Katy, Kathen, Charmaine, Kaletka, Brian, Gonzales, Shania, Worwa, Cathy, Fisher, Molly, Richter, Tyler, Ginder, Alexander, Reich, Brixen, Rau, Carrie, Loertscher, Manndi, Cole, Laura, McGrath, Kandace, Lewis, Kimberlee Weaver, Burnett, Jill, Schaefer, Susan, Bird, Karie, Giblin, Clare, Daly, Rita, Lanier, Kristi, Warden, Kelly, Wassenaar, Jenna, Ericksen, Jensina, Davern, Bridget, Osborne, Mary Pat, Talele, Neha, Obregon, Evelyn, Ziyeh, Tiglath, Clarke, Molly, Wegner, Rachel E., Patel, Palak, Schau, Molly, Russow, Annamarie, Curry, Kelly, Barnhart, Lisa, Parkinson, Charlamaine, Beauman, Sandra, Hanson, Mary, Kuan, Elizabeth, Lacy, Conra Backstrom, Galvis, Edshelee M., Bombino, Susana, Martinez, Denise, Bell, Suzi, Long, Corrie, Nefcy, Christopher, Konodi, Mark A., Hartman, Phuong T. Vu Adam, O?Shea, T. Michael, Ballard, Roberta, O?Shea, Mike, Kuban, Karl, Lowe, Jean, and Widness, John

Published
2022
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37. The Impact of Pulmonary Hypertension in Preterm Infants with Severe BPD Through One Year

Author

Lagatta, Joanne M, Hysinger, Erik B, Zaniletti, Isabella, Wymore, Erica M, Vyas-Read, Shilpa, Yallapragada, Sushmita, Nelin, Leif D, Truog, William E, Padula, Michael A, Porta, Nicolas FM, Savani, Rashmin C, Potoka, Karin P, Kawut, Steven M, DiGeronimo, Robert, Natarajan, Girija, Zhang, Huayan, Grover, Theresa, Engle, William, and Murthy, Karna

Subjects
Male, Hypertension, Pulmonary, Infant, Newborn, Infant, Gestational Age, Comorbidity, Prognosis, Patient Readmission, Severity of Illness Index, Article, Echocardiography, Doppler, Cohort Studies, Survival Rate, Pregnancy, Multivariate Analysis, Intensive Care, Neonatal, Prevalence, Humans, Regression Analysis, Female, Hospital Mortality, Infant, Premature, Bronchopulmonary Dysplasia, Retrospective Studies
Abstract

OBJECTIVE(S): To assess the effect of pulmonary hypertension on NICU mortality and hospital readmission through one year corrected age in infants with severe bronchopulmonary dysplasia with a large, multicenter cohort. STUDY DESIGN: This was a multicenter, retrospective cohort study of 1677 infants born 2 L/min flow by nasal cannula, or fraction of inspired oxygen (F(i)O(2)) >0.3 at 36 weeks’ postmenstrual age) enrolled in the Children’s Hospital Neonatal Consortium with records linked to the Pediatric Health Information System. RESULTS: Pulmonary hypertension occurred in 370/1677 (22%) infants. During the neonatal admission, pulmonary hypertension was associated with mortality (OR= 3.15, 95%CI 2.10–4.73, p

Published
2018

38. Clara Royer, Petra James (eds.), Sans faucille ni marteau : ruptures et retours dans les littératures post-communistes

Author

Porta, Nicolas

Abstract

Entre présentations scientifiques et découvertes littéraires L’ouvrage Sans faucille ni marteau : ruptures et retours dans les littératures post-communistes dirigé par Clara Royer et Petra James, rassemble des articles scientifiques, issus de trois rencontres qui eurent lieu à Paris entre 2010 et 2011, de différents chercheurs, traducteurs et historiens de la littérature sur le thème des littératures post-communistes et des nouvelles ou extraits de romans de quelques auteurs souvent présentés...

Published
2018

39. Predicting Risk of Infection in Infants with Congenital Diaphragmatic Hernia

Author

Murthy, Karna, primary, Porta, Nicolas F.M., additional, Pallotto, Eugenia K., additional, Rintoul, Natalie, additional, Keene, Sarah, additional, Chicoine, Louis, additional, Gien, Jason, additional, Brozanski, Beverly S., additional, Johnson, Yvette R., additional, Haberman, Beth, additional, DiGeronimo, Robert, additional, Zaniletti, Isabella, additional, Grover, Theresa R., additional, Asselin, Jeanette, additional, Durand, David, additional, Dykes, Francine, additional, Evans, Jacquelyn, additional, Murthy, Karna, additional, Padula, Michael, additional, Pallotto, Eugenia, additional, Grover, Theresa, additional, Brozanski, Beverly, additional, Piazza, Anthony, additional, Reber, Kristina, additional, and Short, Billie, additional

Published
2018
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40. Acquired Infection and Antimicrobial Utilization During Initial NICU Hospitalization in Infants With Congenital Diaphragmatic Hernia

Author

Keene, Sarah, primary, Murthy, Karna, additional, Pallotto, Eugenia, additional, Brozanski, Beverly, additional, Gien, Jason, additional, Zaniletti, Isabella, additional, Hulbert, Cheryl, additional, Seabrook, Ruth, additional, Rintoul, Natalie, additional, Chicoine, Louis, additional, Porta, Nicolas, additional, and Grover, Theresa R., additional

Published
2018
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45. Utility of echocardiography in predicting mortality in infants with severe bronchopulmonary dysplasia

Author

Vyas-Read, Shilpa, Wymore, Erica M., Zaniletti, Isabella, Murthy, Karna, Padula, Michael A., Truog, William E., Engle, William A., Savani, Rashmin C., Yallapragada, Sushmita, Logan, J. Wells, Zhang, Huayan, Hysinger, Erik B., Grover, Theresa R., Natarajan, Girija, Nelin, Leif D., Porta, Nicolas F. M., Potoka, Karin P., DiGeronimo, Robert, and Lagatta, Joanne M.

Abstract

Objective: To determine the relationship between interventricular septal position (SP) and right ventricular systolic pressure (RVSP) and mortality in infants with severe BPD (sBPD). Study design: Infants with sBPD in the Children’s Hospitals Neonatal Database who had echocardiograms 34–44 weeks’ postmenstrual age (PMA) were included. SP and RVSP were categorized normal, abnormal (flattened/bowed SP or RVSP > 40 mmHg) or missing. Results: Of 1157 infants, 115 infants (10%) died. Abnormal SP or RVSP increased mortality (SP 19% vs. 8% normal/missing, RVSP 20% vs. 9% normal/missing, both p&lt; 0.01) in unadjusted and multivariable models, adjusted for significant covariates (SP OR 1.9, 95% CI 1.2–3.0; RVSP OR 2.2, 95% CI 1.1–4.7). Abnormal parameters had high specificity (SP 82%; RVSP 94%), and negative predictive value (SP 94%, NPV 91%) for mortality. Conclusions: Abnormal SP or RVSP is independently associated with mortality in sBPD infants. Negative predictive values distinguish infants most likely to survive.

Published
2020
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49. Variability for age at successful extubation in infants with congenital diaphragmatic hernia.

Author

Porta, Nicolas F.M., Naing, Khatija, Keene, Sarah, Grover, Theresa R., Hedrick, Holly, Mahmood, Burhan, Seabrook, Ruth, Daniel IV, John, Harrison, Allen, Weems, Mark F., Yoder, Bradley A., DiGeronimo, Robert, Haberman, Beth, Dariya, Vedanta, Guner, Yigit, Rintoul, Natalie E., Murthy, Karna, and CHNC CDH Focus Group

Abstract

Objective: The objective of this study was to characterize clinical factors associated with successful extubation in infants with congenital diaphragmatic hernia.Study Design: Using the Children's Hospitals Neonatal Database, we identified infants with congenital diaphragmatic hernia from 2017 to 2020 at 32 centers. The main outcome was age in days at the time of successful extubation, defined as the patient remaining extubated for 7 consecutive days. Unadjusted Kaplan-Meier and multivariable Cox proportional hazards ratio equations were used to estimate associations between clinical factors and the main outcome. Observations occurred through 180 days after birth.Results: There were 840 eligible neonates with a median gestational age of 38 weeks and birth weight of 3.0 kg. Among survivors (n = 693), the median age at successful extubation was 15 days (interquartile range [IQR]: 8-29 days, 95th percentile: 71 days). For nonsurvivors (n = 147), the median age at death was 21 days (IQR: 11-39 days, 95th percentile: 110 days). Center (adjusted hazards ratio: 0.22-15, P < .01), low birth weight, intrathoracic liver position, congenital heart disease, lower 5-minute Apgar score, lower pH upon admission to Children's Hospitals Neonatal Database center, and use of extracorporeal support were independently associated with older age at successful extubation. Tracheostomy was associated with multiple failed extubations.Conclusion: Our findings suggest that infants who have not successfully extubated by about 3 months of age may be candidates for tracheostomy with chronic mechanical ventilation or palliation. The variability of timing of successful extubation among our centers supports the development of practice guidelines after validating clinical criteria. [ABSTRACT FROM AUTHOR]

Published
2023
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