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15 results on '"Porro, Giampiero"'

1. An integrated device for fast and sensitive immunosuppressant detection

Author

Tombelli, Sara, Trono, Cosimo, Berneschi, Simone, Berrettoni, Chiara, Giannetti, Ambra, Bernini, Romeo, Persichetti, Gianluca, Testa, Genni, Orellana, Guillermo, Salis, Francesca, Weber, Susanne, Luppa, Peter B., Porro, Giampiero, Quarto, Giovanna, Schubert, Markus, Berner, Marcel, Freitas, Paulo P., Cardoso, Susana, Franco, Fernando, Silverio, Vânia, Lopez-Martinez, Maria, Hilbig, Urs, Freudenberger, Kathrin, Gauglitz, Günter, Becker, Holger, Gärtner, Claudia, O’Connell, Mark T., and Baldini, Francesco

Published
2022
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2. An integrated device for fast and sensitive immunosuppressant detection

Author

Tombelli, Sara, primary, Trono, Cosimo, additional, Berneschi, Simone, additional, Berrettoni, Chiara, additional, Giannetti, Ambra, additional, Bernini, Romeo, additional, Persichetti, Gianluca, additional, Testa, Genni, additional, Orellana, Guillermo, additional, Salis, Francesca, additional, Weber, Susanne, additional, Luppa, Peter B., additional, Porro, Giampiero, additional, Quarto, Giovanna, additional, Schubert, Markus, additional, Berner, Marcel, additional, Freitas, Paulo P., additional, Cardoso, Susana, additional, Franco, Fernando, additional, Silverio, Vânia, additional, Lopez-Martinez, Maria, additional, Hilbig, Urs, additional, Freudenberger, Kathrin, additional, Gauglitz, Günter, additional, Becker, Holger, additional, Gärtner, Claudia, additional, O’Connell, Mark T., additional, and Baldini, Francesco, additional

Published
2021
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4. An integrated device for fast and sensitive immunosuppressant detection

Author

Tombelli, Sara, Trono, Cosimo, Berneschi, Simone, Berrettoni, Chiara, Giannetti, Ambra, Bernini, Romeo, Persichetti, Gianluca, Testa, Genni, Orellana, Guillermo, Salis, Francesca, Weber, Susanne, Luppa, Peter B., Porro, Giampiero, Quarto, Giovanna, Schubert, Markus, Berner, Marcel, Freitas, Paulo P., Cardoso, Susana, Franco, Fernando, Silverio, Vania, Lopez-Martinez, Maria, Hilbig, Urs, Freudenberger, Kathrin, Gauglitz, Gunter, Becker, Holger, Gartner, Claudia, O'Connell, Mark T., and Baldini, Francesco

Subjects
Cyclosporine A, Mycophenolic acid, POCT, Fluorescence, Immunosuppressant
Abstract

The present paper describes a compact point of care (POC) optical device for therapeutic drug monitoring (TDM). The core of the device is a disposable plastic chip where an immunoassay for the determination of immunosuppressants takes place. The chip is designed in order to have ten parallel microchannels allowing the simultaneous detection of more than one analyte with replicate measurements. The device is equipped with a microfluidic system, which provides sample mixing with the necessary chemicals and pumping samples, reagents and buffers into the measurement chip, and with integrated thin film amorphous silicon photodiodes for the fluorescence detection. Submicrometric fluorescent magnetic particles are used as support in the immunoassay in order to improve the efficiency of the assay. In particular, the magnetic feature is used to concentrate the antibody onto the sensing layer leading to a much faster implementation of the assay, while the fluorescent feature is used to increase the optical signal leading to a larger optical dynamic change and consequently a better sensitivity and a lower limit of detection. The design and development of the whole integrated optical device are here illustrated. In addition, detection of mycophenolic acid and cyclosporine A in spiked solutions and in microdialysate samples from patient blood with the implemented device are reported.

Published
2021
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5. Point-of-Care System for HTLV-1 Proviral Load Quantification by Digital Mediator Displacement LAMP

Author

Becherer, Lisa, primary, Hess, Jacob Friedrich, additional, Frischmann, Sieghard, additional, Bakheit, Mohammed, additional, Nitschko, Hans, additional, Stinco, Silvina, additional, Zitz, Friedrich, additional, Hofer, Hannes, additional, Porro, Giampiero, additional, Hausladen, Florian, additional, Stock, Karl, additional, Drossart, Dominik, additional, Wurm, Holger, additional, Kuhn, Hanna, additional, Huber, Dominik, additional, Hutzenlaub, Tobias, additional, Paust, Nils, additional, Keller, Mark, additional, Strohmeier, Oliver, additional, Wadle, Simon, additional, Borst, Nadine, additional, Zengerle, Roland, additional, and von Stetten, Felix, additional

Published
2021
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8. Novel fluorescence-based POCT platform for therapeutic drug monitoring in transplanted patients (Conference Presentation)

Author

Baldini, Francesco, primary, Berrettoni, Chiara, additional, Giannetti, Ambra, additional, Tombelli, Sara, additional, Trono, Cosimo, additional, Porro, Giampiero, additional, Bernini, Romeo, additional, Grimaldi, Immacolata Angelica, additional, Testa, Genni, additional, Persichetti, Gianluca, additional, Gärtner, Claudia, additional, Becker, Holger, additional, Berner, Marcel, additional, Schubert, Markus B., additional, O'Connell, Mark T., additional, Carney, Daniel, additional, Orellana, Guillermo, additional, Descalzo, Ana B., additional, Salis, Francesca, additional, Freitas, Paulo P., additional, Luppa, Peter B., additional, Bittersohl, Heike, additional, Gauglitz, Günter, additional, Hilbig, Urs, additional, and Freudenberger, Kathrin, additional

Published
2017
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9. Novel fluorescence-based POCT platform for therapeutic drug monitoring in transplanted patients (Conference Presentation)

Author

Coté, Gerard L., Baldini, Francesco, Berrettoni, Chiara, Giannetti, Ambra, Tombelli, Sara, Trono, Cosimo, Porro, Giampiero, Bernini, Romeo, Grimaldi, Immacolata Angelica, Testa, Genni, Persichetti, Gianluca, Gärtner, Claudia, Becker, Holger, Berner, Marcel, Schubert, Markus B., O'Connell, Mark T., Carney, Daniel, Orellana, Guillermo, Descalzo, Ana B., Salis, Francesca, Freitas, Paulo P., Luppa, Peter B., Bittersohl, Heike, Gauglitz, Günter, Hilbig, Urs, and Freudenberger, Kathrin

Published
2017
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15. FLYING CARS WERE LOSER IN ITALY, TOO.

Author

Porro, Giampiero

Subjects
*LETTERS to the editor, *FLYING automobiles
Abstract

A letter to the editor is presented in response to the article about roadable aircraft in the January 2007 issue.

Published
2007

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