38 results on '"Popovici-Muller, Janeta"'
Search Results
2. AG-348 enhances pyruvate kinase activity in red blood cells from patients with pyruvate kinase deficiency
3. A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition
4. Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase
5. Biochemical, Cellular, and Biophysical Characterization of a Potent Inhibitor of Mutant Isocitrate Dehydrogenase IDH1
6. The identification of novel 5′-amino gemcitabine analogs as potent RRM1 inhibitors
7. An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells
8. Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation
9. Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer
10. Preclinical Drug Metabolism, Pharmacokinetic, and Pharmacodynamic Profiles of Ivosidenib, an Inhibitor of Mutant Isocitrate Dehydrogenase 1 for Treatment of Isocitrate Dehydrogenase 1-Mutant Malignancies
11. Method for quantitative protein-ligand affinity measurements in compound mixtures
12. Correction: Corrigendum: Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer
13. Vorasidenib (AG-881): A First-in-Class, Brain-Penetrant Dual Inhibitor of Mutant IDH1 and 2 for Treatment of Glioma
14. Fused bi-heteroaryl substituted hydantoin compounds as TACE inhibitors
15. Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers
16. Abstract B126: AG-881, a brain penetrant, potent, pan-mutant IDH (mIDH) inhibitor for use in mIDH solid and hematologic malignancies
17. Syntheses of 5′-amino-2′,5′-dideoxy-2′,2′-difluorocytidine derivatives as novel anticancer nucleoside analogs
18. Modulating the interaction between CDK2 and cyclin A with a quinoline-based inhibitor
19. Erratum: Corrigendum: Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer
20. 2-(2-Aminothiazol-4-yl)pyrrolidine-based tartrate diamides as potent, selective and orally bioavailable TACE inhibitors
21. Structure and activity relationships of tartrate-based TACE inhibitors
22. Discovery and SAR of hydantoin TACE inhibitors
23. The discovery of novel tartrate-based TNF-α converting enzyme (TACE) inhibitors
24. Novel TNF-α converting enzyme (TACE) inhibitors as potential treatment for inflammatory diseases
25. AG-120, an Oral, Selective, First-in-Class, Potent Inhibitor of Mutant IDH1, Reduces Intracellular 2HG and Induces Cellular Differentiation in TF-1 R132H Cells and Primary Human IDH1 Mutant AML Patient Samples Treated Ex Vivo
26. Abstract 1194: IDH1 mutant inhibitor induces cellular differentiation and offers a combination benefit with Ara-C in a primary human Idh1 mutant AML xenograft model
27. ChemInform Abstract: Syntheses of 5′-Amino-2′,5′-dideoxy-2′,2′-difluorocytidine Derivatives as Novel Anticancer Nucleoside Analogues.
28. Pyrazolo[1,5- a]pyrimidine-based inhibitors of HCV polymerase
29. Discovery of 4 H-pyrazolo[1,5- a]pyrimidin-7-ones as potent inhibitors of hepatitis C virus polymerase
30. Small Molecule Activation Of Pyruvate Kinase Normalizes Metabolic Activity In Red Cells From Patients With Pyruvate Kinase Deficiency-Associated Hemolytic Anemia
31. IDH1 Mutant Inhibitor Induces Cellular Differentiation and Offers a Combination Benefit With Ara-C In a Primary Human Idh1 Mutant AML Xenograft Model
32. Mutation Selective IDH Inhibitors Mediate Histone and DNA Methylation Changes
33. Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG in Vivo
34. Abstract LB-164: IDH mutations and tumorgenicity
35. Abstract 2785: Modulating the interaction between cdk2 and cyclin A: Screening, synthesis and characterization of a quinoline-based inhibitor
36. Discovery of 4H-pyrazolo[1,5-a]pyrimidin-7-ones as potent inhibitors of hepatitis C virus polymerase
37. Aminothiazole inhibitors of HCV RNA polymerase
38. Corrigendum: Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer.
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.