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1,391 results on '"Pontén, Fredrik"'

2. A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen

Author

Landegren, Nils, Ishii, Norito, Aranda-Guillén, Maribel, Gunnarsson, Hörður Ingi, Sardh, Fabian, Hallgren, Åsa, Ståhle, Mona, Hagforsen, Eva, Bradley, Maria, Edqvist, Per-Henrik D., Pontén, Fredrik, Mäkitie, Outi, Eidsmo, Liv, Norlén, Lars, Achour, Adnane, Dahlbom, Ingrid, Korponay-Szabó, Ilma, Agardh, Daniel, Alimohammadi, Mohammad, Eriksson, Daniel, Hashimoto, Takashi, and Kämpe, Olle

Published
2021

4. Author Correction: Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level

Author

Wang, Fei, Ding, Peiwen, Liang, Xue, Ding, Xiangning, Brandt, Camilla Blunk, Sjöstedt, Evelina, Zhu, Jiacheng, Bolund, Saga, Zhang, Lijing, de Rooij, Laura P. M. H., Luo, Lihua, Wei, Yanan, Zhao, Wandong, Lv, Zhiyuan, Haskó, János, Li, Runchu, Qin, Qiuyu, Jia, Yi, Wu, Wendi, Yuan, Yuting, Pu, Mingyi, Wang, Haoyu, Wu, Aiping, Xie, Lin, Liu, Ping, Chen, Fang, Herold, Jacqueline, Kalucka, Joanna, Karlsson, Max, Zhang, Xiuqing, Helmig, Rikke Bek, Fagerberg, Linn, Lindskog, Cecilia, Pontén, Fredrik, Uhlen, Mathias, Bolund, Lars, Jessen, Niels, Jiang, Hui, Xu, Xun, Yang, Huanming, Carmeliet, Peter, Mulder, Jan, Chen, Dongsheng, Lin, Lin, and Luo, Yonglun

Published
2022
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5. Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level

Author

Wang, Fei, Ding, Peiwen, Liang, Xue, Ding, Xiangning, Brandt, Camilla Blunk, Sjöstedt, Evelina, Zhu, Jiacheng, Bolund, Saga, Zhang, Lijing, de Rooij, Laura P. M. H., Luo, Lihua, Wei, Yanan, Zhao, Wandong, Lv, Zhiyuan, Haskó, János, Li, Runchu, Qin, Qiuyu, Jia, Yi, Wu, Wendi, Yuan, Yuting, Pu, Mingyi, Wang, Haoyu, Wu, Aiping, Xie, Lin, Liu, Ping, Chen, Fang, Herold, Jacqueline, Kalucka, Joanna, Karlsson, Max, Zhang, Xiuqing, Helmig, Rikke Bek, Fagerberg, Linn, Lindskog, Cecilia, Pontén, Fredrik, Uhlen, Mathias, Bolund, Lars, Jessen, Niels, Jiang, Hui, Xu, Xun, Yang, Huanming, Carmeliet, Peter, Mulder, Jan, Chen, Dongsheng, Lin, Lin, and Luo, Yonglun

Published
2022
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6. Genome-wide annotation of protein-coding genes in pig

Author

Karlsson, Max, Sjöstedt, Evelina, Oksvold, Per, Sivertsson, Åsa, Huang, Jinrong, Álvez, María Bueno, Arif, Muhammad, Li, Xiangyu, Lin, Lin, Yu, Jiaying, Ma, Tao, Xu, Fengping, Han, Peng, Jiang, Hui, Mardinoglu, Adil, Zhang, Cheng, von Feilitzen, Kalle, Xu, Xun, Wang, Jian, Yang, Huanming, Bolund, Lars, Zhong, Wen, Fagerberg, Linn, Lindskog, Cecilia, Pontén, Fredrik, Mulder, Jan, Luo, Yonglun, and Uhlen, Mathias

Published
2022
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8. CD93 maintains endothelial barrier function and limits metastatic dissemination

Author

Vemuri, Kalyani, primary, de Alves Pereira, Beatriz, additional, Fuenzalida, Patricia, additional, Subashi, Yelin, additional, Barbera, Stefano, additional, van Hooren, Luuk, additional, Hedlund, Marie, additional, Pontén, Fredrik, additional, Lindskog, Cecilia, additional, Olsson, Anna-Karin, additional, Lugano, Roberta, additional, and Dimberg, Anna, additional

Published
2024
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9. Transcriptome Analysis Reveals Distinct Patterns Between the Invasive and Noninvasive Pituitary Neuroendocrine Tumors

Author

Jotanovic, Jelena, primary, Tebani, Abdellah, additional, Hekmati, Neda, additional, Sivertsson, Åsa, additional, Lindskog, Cecilia, additional, Uhlèn, Mathias, additional, Gudjonsson, Olafur, additional, Tsatsaris, Erika, additional, Engström, Britt Edén, additional, Wikström, Johan, additional, Pontén, Fredrik, additional, and Casar-Borota, Olivera, additional

Published
2024
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11. Effect of preoperative chemotherapy on the histopathological classification of gastric cancer

Author

Caspers, I. A., Biesma, H. D., Wiklund, K., Pontén, Fredrik, Lind, P., Nordsmark, M., Sikorska, K., Meershoek-KleinKranenbarg, E., Hartgrink, H. H., van de Velde, C. J. H., van Sandick, J. W., Verheij, M., Cats, A., van Grieken, N. C. T., Caspers, I. A., Biesma, H. D., Wiklund, K., Pontén, Fredrik, Lind, P., Nordsmark, M., Sikorska, K., Meershoek-KleinKranenbarg, E., Hartgrink, H. H., van de Velde, C. J. H., van Sandick, J. W., Verheij, M., Cats, A., and van Grieken, N. C. T.

Abstract

Background: In the era of individualized gastric cancer (GC) treatment, accurate determination of histological subtype becomes increasingly relevant. As yet, it is unclear whether preoperative chemotherapy may affect the histological subtype. The aim of this study was to assess concordance in histological subtype between pretreatment biopsies and surgical resection specimens before and after the introduction of perioperative treatment. Methods: Histological subtype was centrally determined in paired GC biopsies and surgical resection specimens of patients treated with either surgery alone (SA) in the Dutch D1/D2 study or with preoperative chemotherapy (CT) in the CRITICS trial. The histological subtype as determined in the resection specimen was considered the gold standard. Concordance rates and sensitivity and specificity of intestinal, diffuse, mixed, and "other" subtypes of GC were analyzed. Results: In total, 105 and 515 pairs of GC biopsies and resection specimens of patients treated in the SA and CT cohorts, respectively, were included. Overall concordance in the histological subtype was 72% in the SA and 74% in the CT cohort and substantially higher in the diffuse subtype (83% and 86%) compared to the intestinal (70% and 74%), mixed (21% and 33%) and "other" subtypes (54% and 54%). In the SA cohort, sensitivities and specificities were 0.88 and 0.71 in the intestinal, 0.67 and 0.93 in the diffuse, 0.20 and 0.98 in the mixed, and 0.50 and 0.93 in the "other" subtypes, respectively. Conclusion: Our results suggest that accurate determination of histological subtype on gastric cancer biopsies is suboptimal but that the impact of preoperative chemotherapy on histological subtype is negligible.

Published
2024
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12. A human stomach cell type transcriptome atlas

Author

Öling, S., Struck, E., Noreen-Thorsen, M., Zwahlen, M., von Feilitzen, K., Odeberg, J., Pontén, Fredrik, Lindskog, Cecilia, Uhlén, M., Dusart, P., Butler, L. M., Öling, S., Struck, E., Noreen-Thorsen, M., Zwahlen, M., von Feilitzen, K., Odeberg, J., Pontén, Fredrik, Lindskog, Cecilia, Uhlén, M., Dusart, P., and Butler, L. M.

Abstract

Background The identification of cell type-specific genes and their modification under different conditions is central to our understanding of human health and disease. The stomach, a hollow organ in the upper gastrointestinal tract, provides an acidic environment that contributes to microbial defence and facilitates the activity of secreted digestive enzymes to process food and nutrients into chyme. In contrast to other sections of the gastrointestinal tract, detailed descriptions of cell type gene enrichment profiles in the stomach are absent from the major single-cell sequencing-based atlases. Results Here, we use an integrative correlation analysis method to predict human stomach cell type transcriptome signatures using unfractionated stomach RNAseq data from 359 individuals. We profile parietal, chief, gastric mucous, gastric enteroendocrine, mitotic, endothelial, fibroblast, macrophage, neutrophil, T-cell, and plasma cells, identifying over 1600 cell type-enriched genes. Conclusions We uncover the cell type expression profile of several non-coding genes strongly associated with the progression of gastric cancer and, using a sex-based subset analysis, uncover a panel of male-only chief cell-enriched genes. This study provides a roadmap to further understand human stomach biology.

Published
2024
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13. CD93 maintains endothelial barrier function and limits metastatic dissemination

Author

Vemuri, Kalyani, de Alves Pereira, Beatriz, Fuenzalida, Patricia, Subashi, Yelin, Barbera, Stefano, van Hooren, Luuk, Hedlund, Marie, Pontén, Fredrik, Lindskog, Cecilia, Olsson, Anna-Karin, Lugano, Roberta, Dimberg, Anna, Vemuri, Kalyani, de Alves Pereira, Beatriz, Fuenzalida, Patricia, Subashi, Yelin, Barbera, Stefano, van Hooren, Luuk, Hedlund, Marie, Pontén, Fredrik, Lindskog, Cecilia, Olsson, Anna-Karin, Lugano, Roberta, and Dimberg, Anna

Abstract

Compromised vascular integrity facilitates extravasation of cancer cells and promotes metastatic dissemination. CD93 has emerged as a target for antiangiogenic therapy, but its importance for vascular integrity in metastatic cancers has not been evaluated. Here, we demonstrate that CD93 participates in maintaining the endothelial barrier and reducing metastatic dissemination. Primary melanoma growth was hampered in CD93–/– mice, but metastatic dissemination was increased and associated with disruption of adherens and tight junctions in tumor endothelial cells and elevated expression of matrix metalloprotease 9 at the metastatic site. CD93 directly interacted with vascular endothelial growth factor receptor 2 (VEGFR2) and its absence led to VEGF-induced hyperphosphorylation of VEGFR2 in endothelial cells. Antagonistic anti-VEGFR2 antibody therapy rescued endothelial barrier function and reduced the metastatic burden in CD93–/– mice to wild-type levels. These findings reveal a key role of CD93 in maintaining vascular integrity, which has implications for pathological angiogenesis and endothelial barrier function in metastatic cancer., De två sista författarna delar sistaförfattarskapet

Published
2024
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14. Transcriptome Analysis Reveals Distinct Patterns Between the Invasive and Noninvasive Pituitary Neuroendocrine Tumors

Author

Jotanovic, Jelena, Abdellah, Tebani, Hekmati, Neda, Sivertsson, Åsa, Lindskog, Cecilia, Uhlén, Mathias, Gudjonsson, Olafur, Tsatsaris, Erika, Engström, Britt Eden, Wikstrom, Johan, Pontén, Fredrik, Casar-Borota, Olivera, Jotanovic, Jelena, Abdellah, Tebani, Hekmati, Neda, Sivertsson, Åsa, Lindskog, Cecilia, Uhlén, Mathias, Gudjonsson, Olafur, Tsatsaris, Erika, Engström, Britt Eden, Wikstrom, Johan, Pontén, Fredrik, and Casar-Borota, Olivera

Abstract

Although most pituitary neuroendocrine tumors (PitNETs)/pituitary adenomas remain intrasellar, a significant proportion of tumors show parasellar invasive growth and 6% to 8% infiltrate the bone structures, thus affecting the prognosis. There is an unmet need to identify novel markers that can predict the parasellar growth of PitNETs. Furthermore, mechanisms that regulate bone invasiveness of PitNETs and factors related to tumor vascularization are largely unknown.We used genome-wide mRNA analysis in a cohort of 77 patients with PitNETs of different types to explore the differences in gene expression patterns between invasive and noninvasive tumors with respect to the parasellar growth and regarding the rare phenomenon of bone invasiveness. Additionally, we studied the genes correlated to the contrast enhancement quotient, a novel radiological parameter of tumor vascularization.Most of the genes differentially expressed related to the parasellar growth were genes involved in tumor invasiveness. Differentially expressed genes associated with bone invasiveness are involved in NF-kappa B pathway and antitumoral immune response. Lack of clear clustering regarding the parasellar and bone invasiveness may be explained by the influence of the cell lineage-related genes in this heterogeneous cohort of PitNETs.Our transcriptomics analysis revealed differences in the molecular fingerprints between invasive, including bone invasive, and noninvasive PitNETs, although without clear clustering. The contrast enhancement quotient emerged as a radiological parameter of tumor vascularization, correlating with several angiogenesis-related genes. Several of the top genes related to the PitNET invasiveness and vascularization have potential prognostic and therapeutic application requiring further research., QC 20240408

Published
2024
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15. The impact of sex on treatment and outcome in relation to histological subtype in patients with resectable gastric cancer : Results from the randomized CRITICS trial

Author

Caspers, Irene A., Slagter, Astrid E., Lind, Pehr, Sikorska, Karolina, Wiklund, Katja, Pontén, Fredrik, Nordsmark, Marianne, van de Velde, Cornelis J. H., Meershoek-Klein Kranenbarg, Elma, van Sandick, Johanna W., Jansen, Edwin P. M., van Laarhoven, Hanneke W. M., Verheij, Marcel, van Grieken, Nicole C. T., Cats, Annemieke, Caspers, Irene A., Slagter, Astrid E., Lind, Pehr, Sikorska, Karolina, Wiklund, Katja, Pontén, Fredrik, Nordsmark, Marianne, van de Velde, Cornelis J. H., Meershoek-Klein Kranenbarg, Elma, van Sandick, Johanna W., Jansen, Edwin P. M., van Laarhoven, Hanneke W. M., Verheij, Marcel, van Grieken, Nicole C. T., and Cats, Annemieke

Abstract

Background and Objective This study aims to investigate the impact of sex on outcome measures stratified by histological subtype in patients with resectable gastric cancer (GC). Methods A post-hoc analysis of the CRITICS-trial, in which patients with resectable GC were treated with perioperative therapy, was performed. Histopathological characteristics and survival were evaluated for males and females stratified for histological subtype (intestinal/diffuse). Additionally, therapy-related toxicity and compliance were compared. Results Data from 781 patients (523 males) were available for analyses. Female sex was associated with a distal tumor localization in intestinal (p = 0.014) and diffuse tumors (p < 0.001), and younger age in diffuse GC (p = 0.035). In diffuse GC, tumor-positive resection margins were also more common in females than males (21% vs. 10%; p = 0.020), specifically at the duodenal margin. During preoperative chemotherapy, severe toxicity occurred in 327 (63%) males and 184 (71%) females (p = 0.015). Notwithstanding this, relative dose intensities were not significantly different between sexes. Conclusions Positive distal margin rates were higher in females with diffuse GC, predominantly at the duodenal site. Females also experience more toxicity, but this neither impacts dose intensities nor surgical resection rates. Clinicians should be aware of these different surgical outcomes when treating males and females with GC.

Published
2024
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17. Spatiotemporal dissection of the cell cycle with single-cell proteogenomics

Author

Mahdessian, Diana, Cesnik, Anthony J., Gnann, Christian, Danielsson, Frida, Stenström, Lovisa, Arif, Muhammad, Zhang, Cheng, Le, Trang, Johansson, Fredric, Schutten, Rutger, Bäckström, Anna, Axelsson, Ulrika, Thul, Peter, Cho, Nathan H., Carja, Oana, Uhlén, Mathias, Mardinoglu, Adil, Stadler, Charlotte, Lindskog, Cecilia, Ayoglu, Burcu, Leonetti, Manuel D., Pontén, Fredrik, Sullivan, Devin P., and Lundberg, Emma

Published
2021
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18. The impact of sex on treatment and outcome in relation to histological subtype in patients with resectable gastric cancer: Results from the randomized CRITICS trial

Author

Caspers, Irene A., primary, Slagter, Astrid E., additional, Lind, Pehr, additional, Sikorska, Karolina, additional, Wiklund, Katja, additional, Pontén, Fredrik, additional, Nordsmark, Marianne, additional, van de Velde, Cornelis J. H., additional, Kranenbarg, Elma Meershoek‐Klein, additional, van Sandick, Johanna W., additional, Jansen, Edwin P. M., additional, van Laarhoven, Hanneke W. M., additional, Verheij, Marcel, additional, van Grieken, Nicole C. T., additional, and Cats, Annemieke, additional

Published
2023
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19. The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling

Author

Lindskog, Cecilia, Linné, Jerker, Fagerberg, Linn, Hallström, Björn M, Sundberg, Carl Johan, Lindholm, Malene, Huss, Mikael, Kampf, Caroline, Choi, Howard, Liem, David A, Ping, Peipei, Väremo, Leif, Mardinoglu, Adil, Nielsen, Jens, Larsson, Erik, Pontén, Fredrik, and Uhlén, Mathias

Subjects
Heart Disease, Cardiovascular, Biotechnology, Genetics, Aetiology, Underpinning research, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Musculoskeletal, Antibodies, Gene Expression Profiling, Humans, Muscle, Skeletal, Myocardium, Proteome, Transcriptome, Cardiac and skeletal muscle, Biological Sciences, Information and Computing Sciences, Medical and Health Sciences, Bioinformatics
Abstract

BackgroundTo understand cardiac and skeletal muscle function, it is important to define and explore their molecular constituents and also to identify similarities and differences in the gene expression in these two different striated muscle tissues. Here, we have investigated the genes and proteins with elevated expression in cardiac and skeletal muscle in relation to all other major human tissues and organs using a global transcriptomics analysis complemented with antibody-based profiling to localize the corresponding proteins on a single cell level.ResultsOur study identified a comprehensive list of genes expressed in cardiac and skeletal muscle. The genes with elevated expression were further stratified according to their global expression pattern across the human body as well as their precise localization in the muscle tissues. The functions of the proteins encoded by the elevated genes are well in line with the physiological functions of cardiac and skeletal muscle, such as contraction, ion transport, regulation of membrane potential and actomyosin structure organization. A large fraction of the transcripts in both cardiac and skeletal muscle correspond to mitochondrial proteins involved in energy metabolism, which demonstrates the extreme specialization of these muscle tissues to provide energy for contraction.ConclusionsOur results provide a comprehensive list of genes and proteins elevated in striated muscles. A number of proteins not previously characterized in cardiac and skeletal muscle were identified and localized to specific cellular subcompartments. These proteins represent an interesting starting point for further functional analysis of their role in muscle biology and disease.

Published
2015

23. Author Correction: Spatiotemporal dissection of the cell cycle with single-cell proteogenomics

Author

Mahdessian, Diana, Cesnik, Anthony J., Gnann, Christian, Danielsson, Frida, Stenström, Lovisa, Arif, Muhammad, Zhang, Cheng, Le, Trang, Johansson, Fredric, Schutten, Rutger, Bäckström, Anna, Axelsson, Ulrika, Thul, Peter, Cho, Nathan H., Carja, Oana, Uhlén, Mathias, Mardinoglu, Adil, Stadler, Charlotte, Lindskog, Cecilia, Ayoglu, Burcu, Leonetti, Manuel D., Pontén, Fredrik, Sullivan, Devin P., and Lundberg, Emma

Published
2022
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25. Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage

Author

Matic, Ljubica Perisic, Jesus Iglesias, Maria, Vesterlund, Mattias, Lengquist, Mariette, Hong, Mun-Gwan, Saieed, Shanga, Sanchez-Rivera, Laura, Berg, Martin, Razuvaev, Anton, Kronqvist, Malin, Lund, Kent, Caidahl, Kenneth, Gillgren, Peter, Pontén, Fredrik, Uhlén, Mathias, Schwenk, Jochen M., Hansson, Göran K., Paulsson-Berne, Gabrielle, Fagman, Erika, Roy, Joy, Hultgren, Rebecka, Bergström, Göran, Lehtiö, Janne, Odeberg, Jacob, and Hedin, Ulf

Published
2018
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28. A pathology atlas of the human cancer transcriptome

Author

Uhlen, Mathias, Zhang, Cheng, Lee, Sunjae, Sjöstedt, Evelina, Fagerberg, Linn, Bidkhori, Gholamreza, Benfeitas, Rui, Arif, Muhammad, Liu, Zhengtao, Edfors, Fredrik, Sanli, Kemal, von Feilitzen, Kalle, Oksvold, Per, Lundberg, Emma, Hober, Sophia, Nilsson, Peter, Mattsson, Johanna, Schwenk, Jochen M., Brunnström, Hans, Glimelius, Bengt, Sjöblom, Tobias, Edqvist, Per-Henrik, Djureinovic, Dijana, Micke, Patrick, Lindskog, Cecilia, Mardinoglu, Adil, and Ponten, Fredrik

Published
2017

29. A subcellular map of the human proteome

Author

Thul, Peter J., Åkesson, Lovisa, Wiking, Mikaela, Mahdessian, Diana, Geladaki, Aikaterini, Blal, Hammou Ait, Alm, Tove, Asplund, Anna, Björk, Lars, Breckels, Lisa M., Bäckström, Anna, Danielsson, Frida, Fagerberg, Linn, Fall, Jenny, Gatto, Laurent, Gnann, Christian, Hober, Sophia, Hjelmare, Martin, Johansson, Fredric, Lee, Sunjae, Lindskog, Cecilia, Mulder, Jan, Mulvey, Claire M., Nilsson, Peter, Oksvold, Per, Rockberg, Johan, Schutten, Rutger, Schwenk, Jochen M., Sivertsson, Åsa, Sjöstedt, Evelina, Skogs, Marie, Stadler, Charlotte, Sullivan, Devin P., Tegel, Hanna, Winsnes, Casper, Zhang, Cheng, Zwahlen, Martin, Mardinoglu, Adil, Pontén, Fredrik, von Feilitzen, Kalle, Lilley, Kathryn S., Uhlén, Mathias, and Lundberg, Emma

Published
2017

31. Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters

Author

Grinberg, Marianna, Djureinovic, Dijana, Brunnström, Hans RR, Mattsson, Johanna SM, Edlund, Karolina, Hengstler, Jan G, La Fleur, Linnea, Ekman, Simon, Koyi, Hirsh, Branden, Eva, Ståhle, Elisabeth, Jirström, Karin, Tracy, Derek K, Pontén, Fredrik, Botling, Johan, Rahnenführer, Jörg, and Micke, Patrick

Published
2017
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32. Supplementary Table 4 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation

Author

Botling, Johan, primary, Edlund, Karolina, primary, Lohr, Miriam, primary, Hellwig, Birte, primary, Holmberg, Lars, primary, Lambe, Mats, primary, Berglund, Anders, primary, Ekman, Simon, primary, Bergqvist, Michael, primary, Pontén, Fredrik, primary, König, André, primary, Fernandes, Oswaldo, primary, Karlsson, Mats, primary, Helenius, Gisela, primary, Karlsson, Christina, primary, Rahnenführer, Jörg, primary, Hengstler, Jan G, primary, and Micke, Patrick, primary

Published
2023
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33. Supplementary Table 1 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation

Author

Botling, Johan, primary, Edlund, Karolina, primary, Lohr, Miriam, primary, Hellwig, Birte, primary, Holmberg, Lars, primary, Lambe, Mats, primary, Berglund, Anders, primary, Ekman, Simon, primary, Bergqvist, Michael, primary, Pontén, Fredrik, primary, König, André, primary, Fernandes, Oswaldo, primary, Karlsson, Mats, primary, Helenius, Gisela, primary, Karlsson, Christina, primary, Rahnenführer, Jörg, primary, Hengstler, Jan G, primary, and Micke, Patrick, primary

Published
2023
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34. Supplementary Discussion from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation

Author

Botling, Johan, primary, Edlund, Karolina, primary, Lohr, Miriam, primary, Hellwig, Birte, primary, Holmberg, Lars, primary, Lambe, Mats, primary, Berglund, Anders, primary, Ekman, Simon, primary, Bergqvist, Michael, primary, Pontén, Fredrik, primary, König, André, primary, Fernandes, Oswaldo, primary, Karlsson, Mats, primary, Helenius, Gisela, primary, Karlsson, Christina, primary, Rahnenführer, Jörg, primary, Hengstler, Jan G, primary, and Micke, Patrick, primary

Published
2023
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35. Supplementary Figure 1 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation

Author

Botling, Johan, primary, Edlund, Karolina, primary, Lohr, Miriam, primary, Hellwig, Birte, primary, Holmberg, Lars, primary, Lambe, Mats, primary, Berglund, Anders, primary, Ekman, Simon, primary, Bergqvist, Michael, primary, Pontén, Fredrik, primary, König, André, primary, Fernandes, Oswaldo, primary, Karlsson, Mats, primary, Helenius, Gisela, primary, Karlsson, Christina, primary, Rahnenführer, Jörg, primary, Hengstler, Jan G, primary, and Micke, Patrick, primary

Published
2023
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36. Supplementary Table 3 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation

Author

Botling, Johan, primary, Edlund, Karolina, primary, Lohr, Miriam, primary, Hellwig, Birte, primary, Holmberg, Lars, primary, Lambe, Mats, primary, Berglund, Anders, primary, Ekman, Simon, primary, Bergqvist, Michael, primary, Pontén, Fredrik, primary, König, André, primary, Fernandes, Oswaldo, primary, Karlsson, Mats, primary, Helenius, Gisela, primary, Karlsson, Christina, primary, Rahnenführer, Jörg, primary, Hengstler, Jan G, primary, and Micke, Patrick, primary

Published
2023
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37. Supplementary Figure 4 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation

Author

Botling, Johan, primary, Edlund, Karolina, primary, Lohr, Miriam, primary, Hellwig, Birte, primary, Holmberg, Lars, primary, Lambe, Mats, primary, Berglund, Anders, primary, Ekman, Simon, primary, Bergqvist, Michael, primary, Pontén, Fredrik, primary, König, André, primary, Fernandes, Oswaldo, primary, Karlsson, Mats, primary, Helenius, Gisela, primary, Karlsson, Christina, primary, Rahnenführer, Jörg, primary, Hengstler, Jan G, primary, and Micke, Patrick, primary

Published
2023
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38. Supplementary Table 2 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation

Author

Botling, Johan, primary, Edlund, Karolina, primary, Lohr, Miriam, primary, Hellwig, Birte, primary, Holmberg, Lars, primary, Lambe, Mats, primary, Berglund, Anders, primary, Ekman, Simon, primary, Bergqvist, Michael, primary, Pontén, Fredrik, primary, König, André, primary, Fernandes, Oswaldo, primary, Karlsson, Mats, primary, Helenius, Gisela, primary, Karlsson, Christina, primary, Rahnenführer, Jörg, primary, Hengstler, Jan G, primary, and Micke, Patrick, primary

Published
2023
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39. Supplementary Table 5 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation

Author

Botling, Johan, primary, Edlund, Karolina, primary, Lohr, Miriam, primary, Hellwig, Birte, primary, Holmberg, Lars, primary, Lambe, Mats, primary, Berglund, Anders, primary, Ekman, Simon, primary, Bergqvist, Michael, primary, Pontén, Fredrik, primary, König, André, primary, Fernandes, Oswaldo, primary, Karlsson, Mats, primary, Helenius, Gisela, primary, Karlsson, Christina, primary, Rahnenführer, Jörg, primary, Hengstler, Jan G, primary, and Micke, Patrick, primary

Published
2023
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40. Supplementary Figure 3 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation

Author

Botling, Johan, primary, Edlund, Karolina, primary, Lohr, Miriam, primary, Hellwig, Birte, primary, Holmberg, Lars, primary, Lambe, Mats, primary, Berglund, Anders, primary, Ekman, Simon, primary, Bergqvist, Michael, primary, Pontén, Fredrik, primary, König, André, primary, Fernandes, Oswaldo, primary, Karlsson, Mats, primary, Helenius, Gisela, primary, Karlsson, Christina, primary, Rahnenführer, Jörg, primary, Hengstler, Jan G, primary, and Micke, Patrick, primary

Published
2023
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41. Supplementary Figure 2 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation

Author

Botling, Johan, primary, Edlund, Karolina, primary, Lohr, Miriam, primary, Hellwig, Birte, primary, Holmberg, Lars, primary, Lambe, Mats, primary, Berglund, Anders, primary, Ekman, Simon, primary, Bergqvist, Michael, primary, Pontén, Fredrik, primary, König, André, primary, Fernandes, Oswaldo, primary, Karlsson, Mats, primary, Helenius, Gisela, primary, Karlsson, Christina, primary, Rahnenführer, Jörg, primary, Hengstler, Jan G, primary, and Micke, Patrick, primary

Published
2023
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42. Supplemental Figure S1 from Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages

Author

Wallerius, Majken, primary, Wallmann, Tatjana, primary, Bartish, Margarita, primary, Östling, Jeanette, primary, Mezheyeuski, Artur, primary, Tobin, Nicholas P., primary, Nygren, Emma, primary, Pangigadde, Pradeepa, primary, Pellegrini, Paola, primary, Squadrito, Mario Leonardo, primary, Pontén, Fredrik, primary, Hartman, Johan, primary, Bergh, Jonas, primary, De Milito, Angelo, primary, De Palma, Michele, primary, Östman, Arne, primary, Andersson, John, primary, and Rolny, Charlotte, primary

Published
2023
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43. Supplemental Figure Legends from Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages

Author

Wallerius, Majken, primary, Wallmann, Tatjana, primary, Bartish, Margarita, primary, Östling, Jeanette, primary, Mezheyeuski, Artur, primary, Tobin, Nicholas P., primary, Nygren, Emma, primary, Pangigadde, Pradeepa, primary, Pellegrini, Paola, primary, Squadrito, Mario Leonardo, primary, Pontén, Fredrik, primary, Hartman, Johan, primary, Bergh, Jonas, primary, De Milito, Angelo, primary, De Palma, Michele, primary, Östman, Arne, primary, Andersson, John, primary, and Rolny, Charlotte, primary

Published
2023
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44. Supplementary Table S1 from Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Author

Langenkamp, Elise, primary, Zhang, Lei, primary, Lugano, Roberta, primary, Huang, Hua, primary, Elhassan, Tamador Elsir Abu, primary, Georganaki, Maria, primary, Bazzar, Wesam, primary, Lööf, Johan, primary, Trendelenburg, George, primary, Essand, Magnus, primary, Pontén, Fredrik, primary, Smits, Anja, primary, and Dimberg, Anna, primary

Published
2023
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45. Supplementary Figure S3 from Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Author

Langenkamp, Elise, primary, Zhang, Lei, primary, Lugano, Roberta, primary, Huang, Hua, primary, Elhassan, Tamador Elsir Abu, primary, Georganaki, Maria, primary, Bazzar, Wesam, primary, Lööf, Johan, primary, Trendelenburg, George, primary, Essand, Magnus, primary, Pontén, Fredrik, primary, Smits, Anja, primary, and Dimberg, Anna, primary

Published
2023
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46. Supplemental Table S1 from Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages

Author

Wallerius, Majken, primary, Wallmann, Tatjana, primary, Bartish, Margarita, primary, Östling, Jeanette, primary, Mezheyeuski, Artur, primary, Tobin, Nicholas P., primary, Nygren, Emma, primary, Pangigadde, Pradeepa, primary, Pellegrini, Paola, primary, Squadrito, Mario Leonardo, primary, Pontén, Fredrik, primary, Hartman, Johan, primary, Bergh, Jonas, primary, De Milito, Angelo, primary, De Palma, Michele, primary, Östman, Arne, primary, Andersson, John, primary, and Rolny, Charlotte, primary

Published
2023
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47. Supplemental Methods and References from Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages

Author

Wallerius, Majken, primary, Wallmann, Tatjana, primary, Bartish, Margarita, primary, Östling, Jeanette, primary, Mezheyeuski, Artur, primary, Tobin, Nicholas P., primary, Nygren, Emma, primary, Pangigadde, Pradeepa, primary, Pellegrini, Paola, primary, Squadrito, Mario Leonardo, primary, Pontén, Fredrik, primary, Hartman, Johan, primary, Bergh, Jonas, primary, De Milito, Angelo, primary, De Palma, Michele, primary, Östman, Arne, primary, Andersson, John, primary, and Rolny, Charlotte, primary

Published
2023
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48. Data from Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages

Author

Wallerius, Majken, primary, Wallmann, Tatjana, primary, Bartish, Margarita, primary, Östling, Jeanette, primary, Mezheyeuski, Artur, primary, Tobin, Nicholas P., primary, Nygren, Emma, primary, Pangigadde, Pradeepa, primary, Pellegrini, Paola, primary, Squadrito, Mario Leonardo, primary, Pontén, Fredrik, primary, Hartman, Johan, primary, Bergh, Jonas, primary, De Milito, Angelo, primary, De Palma, Michele, primary, Östman, Arne, primary, Andersson, John, primary, and Rolny, Charlotte, primary

Published
2023
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49. Data from Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Author

Langenkamp, Elise, primary, Zhang, Lei, primary, Lugano, Roberta, primary, Huang, Hua, primary, Elhassan, Tamador Elsir Abu, primary, Georganaki, Maria, primary, Bazzar, Wesam, primary, Lööf, Johan, primary, Trendelenburg, George, primary, Essand, Magnus, primary, Pontén, Fredrik, primary, Smits, Anja, primary, and Dimberg, Anna, primary

Published
2023
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50. Supplementary Materials and Methods from Elevated Expression of the C-Type Lectin CD93 in the Glioblastoma Vasculature Regulates Cytoskeletal Rearrangements That Enhance Vessel Function and Reduce Host Survival

Author

Langenkamp, Elise, primary, Zhang, Lei, primary, Lugano, Roberta, primary, Huang, Hua, primary, Elhassan, Tamador Elsir Abu, primary, Georganaki, Maria, primary, Bazzar, Wesam, primary, Lööf, Johan, primary, Trendelenburg, George, primary, Essand, Magnus, primary, Pontén, Fredrik, primary, Smits, Anja, primary, and Dimberg, Anna, primary

Published
2023
Full Text
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