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Polyphenols Understand polyphenols and their benefits with this comprehensive overview Polyphenols are a group of beneficial compounds—including phenolic acids, flavonoids, anthocyanins, and others—that can be found in a vast range of plants and plant-based foods. Their health benefits and the variety of their applications in functional foods, dietary supplements, and similar areas have made polyphenols a $1 billion market, a figure that is expected to more than double in the next decade. This has placed increased emphasis on areas of cutting-edge research such as the use of bio-based nanodelivery systems to improve the oral bioavailability of polyphenols. Polyphenols constitutes a comprehensive introduction to these compounds, their health benefits, and their potential nutraceutical applications. It incorporates both the biochemical fundamentals of polyphenols and their precise potential to prevent numerous common diseases. The result is an essential reference for a vital, growing area of research and industry. Polyphenols readers will also find: Detailed coverage of polyphenols'occurrence, bioactivity, and technological applications In-depth discussion of nano-based delivery systems to increase polyphenols'therapeutic efficacy and oral bioavailability and to reduce required dosages Guidance for developing treatments for cancers, cardiovascular diseases, inflammatory conditions, and more Polyphenols is ideal for food scientists and manufacturers, medicinal chemists, pharmaceutical scientists, and any biochemical or biomedical researcher or professional working with polyphenols or plant-based foods.

SCIENCE AND ENGINEERING OF POLYPHENOLS A groundbreaking synthesis of rich and varied polyphenol research Polyphenols are a class of compounds, found naturally in fruits and vegetables, whose flexibility and ubiquity give them a vast range of applications in pharmaceutical, environmental, and biological research and development. They play a role in diagnosing and preventing diseases from diabetes to Parkinson's to Alzheimer's and have been integral in food preservation. The field of polyphenols research has the potential to touch virtually every area of organic production. Science and Engineering of Polyphenols provides a current and comprehensive overview of this field of research and its latest developments. Long overdue as a ‘state of the field'synthesis for an area of study that has seen rapid development in recent years, this book promises to be a milestone. Science and Engineering of Polyphenols readers will also find: Treatment of both natural and synthetic polyphenols Detailed discussion of topics including synthesis and characterization of polyphenols, electronic and molecular structure of polyphenols, and many more Supplementary material including websites of interest and updates on the latest research and development Science and Engineering of Polyphenols is ideal for scholars, industrialists, and policymakers in any of the myriad areas of academia and industry touched by polyphenol research.

Have you heard of'tea polyphenol'? What is tea polyphenol like? Why does tea have so many benefits? It can be said that tea polyphenols are the soul of tea. The abundance of tea benefits is attributed to tea polyphenols. Through this book, the author expounds on the structure, properties, and healthcare functions of tea polyphenols.This book focuses on the properties and structural characteristics of tea polyphenols, and systematically describes the biological functions of tea polyphenols, especially the free radicals scavenging and antioxidant effects of tea polyphenols, regulation of oxidative stress, protection of nerve cells, anticancer effects, strengthening body immunity, preventing cardiovascular and cerebrovascular diseases, anti-inflammatory effects, reducing blood lipid and blood glucose atherosclerosis, myocardial protection, its role in Alzheimer's disease and Parkinson's disease, anti-aging properties, improving memory, anti-radiation effects, etc. The source and safety of tea polyphenols are also introduced.

This book contains a selection of five chapters each discussing a different aspect of polyphenols and their roles in health and disease. Chapter One reviews the oral health benefits of polyphenols found in cocoa. Chapter Two is an overview of the effects of polyphenols on the microbiota of the gut and the consequent roles these play in health and disease. Chapter Three is a review of potential sources and health benefits of various polyphenols. Chapter Four examines different polyphenols from food and medicinal plants as well as their uses in Mexico. Chapter Five discusses the role of polyphenols in honey and their use as a natural therapeutic.

Diets rich in plant polyphenols or dietary polyphenols are the subject of increasing scientific interest because of their diverse range of health benefits and medicinal uses. This book, Dietary Polyphenols in Human Diseases: Advances and Challenges in Drug Discovery, fills the gap that exists in the current knowledge by presenting the latest information in the area of polyphenol-based drug discovery research. The book focuses on the current understanding of the beneficial effects on human health of diets rich in polyphenols and/or polyphenolic compounds derived from dietary sources (plant-based foods) and their possible preventive role in the management of chronic human diseases. In addition, biochemical mechanisms involved in the antioxidative effect of dietary polyphenols along with their bioavailability, pharmacokinetic, and toxicological considerations are also discussed herein.Key Features Presents health benefits and medicinal importance of dietary polyphenols having antioxidative effects and their possible preventive role against oxidative stress (OS)-induced chronic human diseases. Summarizes the latest understanding of the biochemical mechanism(s) involved in the antioxidative action of dietary polyphenols along with their bioavailability, pharmacokinetic, and toxicological considerations. Highlights novel approaches of drug discovery from dietary polyphenols through computational screening of bioactive phytochemical components. With contributions by a global team of experts (academics, scientists, and researchers), this book is intended to be a useful resource for a wider audience, particularly those working in the area of drug discovery and development research, such as discovery scientists, pharmaceutical scientists (R&D), formulation scientists, medicinal chemists, pharmacologists, toxicologists, phytochemists, biochemists, clinicians, researchers, students, teachers, and many others.

Polyphenolics are compounds found in plants, such as phenolic acid and flavonoids, that have positive effects on human health and help fight disease. As such, studies of these compounds are valuable for those looking to improve their own health or the health of others. Chapter One addresses the role that polyphenolics plays in the assessment of food integrity and authenticity. Chapter Two studies the potential of regular long-term consumption of various fruit species for reducing diabetes mellitus. Chapter Three provides a platform for the selection of solvent for extraction, column and mobile phase for better separation of polyphenol compounds. Chapter Four presents extraction with subcritical water as a technique for polyphenol isolation. Lastly, Chapter Five attempts to bridge the gap between the different ethnomedical and folklore claims of utilization of Amaranth germplasms against degenerative diseases with matching polyphenol-based chemical data having antioxidant and anti-inflammatory properties.

Polyphenolic compounds are part of a division of secondary metabolites with high antioxidant capacity, found naturally in most edible and inedible plants. These compounds are responsible for pigmentation and plants defense of pathogens agents. Its molecular structure includes phenolic hydroxyl groups and aromatic rings. Polyphenols are increasingly studied because of the benefits to human health, introducing the ability to eliminate free radicals generated by oxidation, reducing risk of cancer, anti-aging, anti-diabetic, among others. This book provides new research on food sources of polyphenolic compounds, and their biochemistry and health benefits.

This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed ‘amyloid'. Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alzheimer's disease-related dementia and Parkinson's disease, as well as other less prevalent conditions like Huntington's disease, cerebral amyloid angiopathy and the transmissible prion disorders. A disease-modifying therapeutic agent is still lacking for all these diseases, and there are no approved therapies that target amyloid formation directly. Nevertheless, a large and complex group of natural aromatic compounds known as polyphenols are rapidly emerging as potentially potent anti-amyloidogenic agents.This book collectively presents a considerable body of experimental and epidemiological evidence from peer-reviewed scientific publications that support a role for natural compounds and herbal extracts in the chemoprevention and therapy of amyloidogenic disorders.Each contribution is written by scientific experts in the relevant field; chapters are devoted to Mediterranean diet and olive oil phenols, traditional Chinese medicine, herbal extracts, polyphenols (with a particular emphasis on epigallocatechin-3-gallate) and bi-flavonoids, amongst others.The topic of this book is relevant to a wide audience, from academia and university students in the biological and chemical sciences, to physicians and allied health professionals, as well as people working in the nutraceutical industry.