12 results on '"Polunina EG"'
Search Results
2. Ocular surface viral diseases in children
- Author
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L.V. Venediktova, N.A. Pron'ko, Markova Ey, Polunina Eg, and O. V. Kurganova
- Subjects
Male ,Pediatrics ,medicine.medical_specialty ,Visual acuity ,genetic structures ,Keratoconjunctivitis ,Antiviral Agents ,Moscow ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Child ,business.industry ,Corneal opacity ,Disease Management ,medicine.disease ,Virology ,eye diseases ,Epidemic Keratoconjunctivitis ,Corneal Disorder ,Ophthalmology ,Virus Diseases ,Child, Preschool ,030221 ophthalmology & optometry ,Proper treatment ,Female ,Ophthalmic Solutions ,medicine.symptom ,Disease manifestation ,business ,Ocular surface ,030215 immunology - Abstract
Over the past 15 years the number of children with inflammatory eye diseases has increased by five-six times. Data analysis of Moscow children's health clinics in 2014 showed that for 40,000 outpatients a viral infection was observed in 49,000 cases, whereas some children suffered from the viral infection twice or thrice. 344 children (0.7 percent) had the viral infection accompanied by keratoconjunctivitis. According to 2015 data, viral infection was observed in 37,957 children, including 325 outpatients (0.8 percent) with keratoconjunctivitis.To analyze clinical features and treatment options of ocular surface viral diseases in children.We observed 140 children aged 2 to 13 years with ocular surface viral diseases.Despite the presence of corneal disorders, in 95 percent of children changes were reversible - in 1.5 months corneal opacity was not observed. Yet five percent of children, despite the intensive treatment, had bacterial complications, causing decrease in visual acuity.In case of viral infections, ophthalmologists, pediatricians and general practitioners should all be aware of ocular manifestations of these diseases. Even if adequate therapy for ocular surface viral disorders is appointed, in five percent of cases complications are possible, causing decline in visual function. Changes in vision can be a result of general disease manifestation, and only timely and proper treatment will help to relieve the symptoms of inflammation and prevent complications.The results of our observations revealed that the addition of Ophtalmoferon medication to the complex therapy of ocular surface diseases in children showed a high therapeutic efficacy and a good safety profile. This medication, in contrast to other antiviral agents, is available in the form of ready-to-use eye drops, significantly enhancing medication compliance in outpatients.За последние 15 лет число больных детей с воспалительными заболеваниями глазной поверхности увеличилось в 5-6 раз. Анализ данных детских поликлиник ЮАО Москвы за 2014 г. показал, что на 40 000 прикрепленных детей в 49 000 наблюдений зафиксирована вирусная инфекция, при этом часть детей перенесли вирусную инфекцию дважды или трижды. У 344 (0,7%) человек вирусная инфекция сопровождалась кератоконъюнктивитом. По данным за 2015 г., вирусная инфекция зафиксирована у 37 957 детей, из них у 325 (0,8%) она сопровождалась кератоконъюнктивитом. Цель - анализ особенностей клиники и лечения вирусных заболеваний глазной поверхности у детей. Материал и методы. Под наблюдением находилось 140 детей в возрасте от 2 до 13 лет с вирусными заболеваниями глазной поверхности. Результаты. Несмотря на наличие поражений роговицы, у 95% детей изменения были обратимыми, через 1,5 мес помутнений на роговице не отмечалось. Только в 5% случаев на фоне проводимого интенсивного лечения у детей имелись бактериальные осложнения и в результате отмечалось снижение остроты зрения. Заключение. При вирусных инфекциях офтальмологам, педиатрам и врачам общей практики необходимо помнить о глазных проявлениях этих заболеваний. Даже при назначении адекватной терапии при вирусных поражениях глазной поверхности в 5% случаев возможны осложнения, вызывающие снижение зрительных функций. Изменения органа зрения могут быть проявлением общего заболевания, и только своевременное и качественное лечение позволит купировать симптомы воспаления и предотвратить осложнения. Результаты наших наблюдений показали, что включение препарата 'Офтальмоферон' в комплексную терапию заболеваний глазной поверхности у детей обеспечивает высокую терапевтическую эффективность и хороший профиль безопасности. Лекарственная форма препарата в виде готовых капель выгодно отличает его от других противовирусных средств и повышает комплаентность пациентов.
- Published
- 2016
3. PHS14 - Clinical and Economic Analysis of Eyelid Hygiene Complex for Patients with Meibomian Glands Dysfunction in Russia
- Author
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Trubilin, VN, Polunina, EG, Markova, EY, Bezmelnitsyna, LY, and Meshkov, DO
- Published
- 2016
- Full Text
- View/download PDF
4. [Ocular surface viral diseases in children].
- Author
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Markova EY, Polunina EG, Pron'ko NA, Venediktova LV, and Kurganova OV
- Subjects
- Child, Child, Preschool, Disease Management, Female, Humans, Male, Moscow epidemiology, Ophthalmic Solutions administration & dosage, Antiviral Agents administration & dosage, Keratoconjunctivitis diagnosis, Keratoconjunctivitis drug therapy, Keratoconjunctivitis epidemiology, Keratoconjunctivitis etiology, Keratoconjunctivitis virology, Virus Diseases complications
- Abstract
Unlabelled: Over the past 15 years the number of children with inflammatory eye diseases has increased by five-six times. Data analysis of Moscow children's health clinics in 2014 showed that for 40,000 outpatients a viral infection was observed in 49,000 cases, whereas some children suffered from the viral infection twice or thrice. 344 children (0.7 percent) had the viral infection accompanied by keratoconjunctivitis. According to 2015 data, viral infection was observed in 37,957 children, including 325 outpatients (0.8 percent) with keratoconjunctivitis., Aim: To analyze clinical features and treatment options of ocular surface viral diseases in children., Material and Methods: We observed 140 children aged 2 to 13 years with ocular surface viral diseases., Results: Despite the presence of corneal disorders, in 95 percent of children changes were reversible - in 1.5 months corneal opacity was not observed. Yet five percent of children, despite the intensive treatment, had bacterial complications, causing decrease in visual acuity., Conclusion: In case of viral infections, ophthalmologists, pediatricians and general practitioners should all be aware of ocular manifestations of these diseases. Even if adequate therapy for ocular surface viral disorders is appointed, in five percent of cases complications are possible, causing decline in visual function. Changes in vision can be a result of general disease manifestation, and only timely and proper treatment will help to relieve the symptoms of inflammation and prevent complications.The results of our observations revealed that the addition of Ophtalmoferon medication to the complex therapy of ocular surface diseases in children showed a high therapeutic efficacy and a good safety profile. This medication, in contrast to other antiviral agents, is available in the form of ready-to-use eye drops, significantly enhancing medication compliance in outpatients.
- Published
- 2016
- Full Text
- View/download PDF
5. [Efficacy of lid hygiene in treatment of patients with blepharoconjunctival form of dry eye syndrome].
- Author
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Polunin GS, Zabegaĭlo AO, Makarov IA, Safonova TN, and Polunina EG
- Subjects
- Adult, Eyelids drug effects, Eyelids physiopathology, Female, Humans, Hygiene standards, Male, Middle Aged, Patient Compliance, Patient Education as Topic methods, Tears metabolism, Treatment Outcome, Blepharitis complications, Blepharitis physiopathology, Conjunctivitis complications, Conjunctivitis physiopathology, Dry Eye Syndromes complications, Dry Eye Syndromes drug therapy, Dry Eye Syndromes physiopathology, Dry Eye Syndromes psychology, Hyaluronic Acid therapeutic use, Ophthalmic Solutions therapeutic use, Therapeutic Irrigation methods
- Abstract
A complex of measures for lid hygiene in ocular surface disease is developed. These measures together with tear substitution and antibacterial treatment were revealed to result in elimination of blepharoconjunctivitis and dry eye signs, recovery of tear film and long-time remission, that significantly improved patient's life quality. When using this complex of measures meibomian glands are not damaged and their anatomy and functions are completely preserved. Lid hygiene affects all glands, there is no pain and no local anesthesia needed, normal tear film is formed
- Published
- 2012
6. [Clinical features of the blepharoconjunctivitis type of the dry eye in demodicosis].
- Author
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Polunin GS, Polunina EG, Zabegaĭlo AO, and Gutova VP
- Subjects
- Adult, Aged, Aged, 80 and over, Animals, Blepharitis complications, Blepharitis diagnosis, Conjunctivitis complications, Conjunctivitis diagnosis, Diagnosis, Differential, Dry Eye Syndromes diagnosis, Follow-Up Studies, Humans, Middle Aged, Trombiculiasis complications, Trombiculiasis diagnosis, Trombiculidae, Blepharitis parasitology, Conjunctivitis parasitology, Dry Eye Syndromes complications, Trombiculiasis parasitology
- Abstract
The paper presents data on demodicosis-induced blepharoconjunctivitis complicated by the dry eye, such as predictors, etiology, and pathogenesis of this disease. It gives a concise outline of the life history of mites and their species parasitizing on the human skin cycle and an extended treatment regimen for blepharoconjunctivitis complicated by the dry eye. The time course of changes in the pathological signs of blepharitis is shown when the latter is treated using the given regimen and the treatment is discontinued. The authors provide the data of Schirmer's test and Norn's test, which have been used to support the results of the present investigation. The mechanism of action of the drugs considered in the paper on the eyelids is outlined. There is a tendency for demodicosis-induced blepharoconjunctivitis to be completely eliminated and the signs of the dry eye to be compensated when meticulously chosen therapy, including hygienic measures, is performed.
- Published
- 2008
7. [Present views of the blepharoconjunctival form of the dry eye syndrome].
- Author
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Zabegaĭlo AO, Polunin GS, Polunina EG, and Kasparova EA
- Subjects
- Diagnosis, Differential, Humans, Conjunctiva pathology, Dry Eye Syndromes classification, Dry Eye Syndromes etiology, Dry Eye Syndromes pathology, Eyelids pathology
- Published
- 2007
8. [The features of the clinical course of different forms of the dry eye syndrome are the basis for development of adequate treatment modalities].
- Author
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Polunin GS, Safonova TN, and Polunina EG
- Subjects
- Congresses as Topic, Humans, Prognosis, Retrospective Studies, Russia, Spain, Dry Eye Syndromes classification, Dry Eye Syndromes therapy
- Abstract
The paper presents two classifications of the dry eye syndrome: the Madrid and Russian classifications. The creation of its classification is required for the elaboration of treatment policy for this category of patients. The classifications are based on the scientific data on the epidemiology, etiology, and pathogenesis of the dry eye syndrome. Each classification identifies different forms of the dry eye. The classifications virtually published at the same time do not greatly differ from each other and they reflect the current approach to systematizing different forms of the dry eye. The paper analyzes the Madrid versus Russian classifications.
- Published
- 2006
9. [The clinical results of using specialized laser keratomileusis for the correction of myopia].
- Author
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Kurenkov VV, Sheludchenko VM, Polunin GS, Kurenkova NV, and Polunina EG
- Subjects
- Adult, Aging physiology, Astigmatism etiology, Astigmatism physiopathology, Astigmatism surgery, Female, Follow-Up Studies, Humans, Laser Therapy instrumentation, Laser Therapy statistics & numerical data, Male, Middle Aged, Myopia complications, Myopia physiopathology, Ophthalmologic Surgical Procedures instrumentation, Ophthalmologic Surgical Procedures statistics & numerical data, Postoperative Care, Preoperative Care, Visual Acuity, Cornea surgery, Laser Therapy methods, Myopia surgery, Ophthalmologic Surgical Procedures methods
- Abstract
Laser in-situ keratomileusis has been performed on 2023 eyes of 1162 patients with myopia of 1-18 diopters and complex myopic astigmatism of 0.75-5 diopters. A Hansatome TM 230 HT keratome and Nidek EC 5000 eximer laser device were employed. The resultant refraction and visual acuity were analyzed during one year postoperation in different age groups and groups with myopia of different degree. In myopia of up to 6 diopters high visual acuity without correction (0.93-0.99) was attained in all age groups. In higher myopia, visual acuity has been increasing over the entire period of observation, the gradient of its alteration being 0.17-0.27. The final visual acuity formed in presbiopes during 3 months. The spherical refraction equivalent of up to 1 diopter was 96.1%. The mean refraction values were stable during the entire period of observation. In myopia of 9.5 diopters and higher the residual myopia in patients aged over 30 years was approximating 1.0 diopters. Hypercorrection was observed in 1.3%, hypocorrection in 2.6% cases. The described combination of equipment for laser keratomileusis provides stable visual and refraction results at a lower incidence of complications.
- Published
- 1999
10. The corneal barrier function in myopic eyes after laser in situ keratomileusis and after photorefractive keratectomy in eyes with haze formation.
- Author
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Polunin GS, Kourenkov VV, Makarov IA, and Polunina EG
- Subjects
- Adolescent, Adult, Cornea metabolism, Cornea surgery, Corneal Opacity etiology, Corneal Opacity metabolism, Corneal Transplantation adverse effects, Densitometry, Fluorescein metabolism, Fluorescent Dyes metabolism, Follow-Up Studies, Humans, Laser Therapy, Lasers, Excimer, Middle Aged, Myopia metabolism, Myopia surgery, Permeability, Photorefractive Keratectomy adverse effects, Prognosis, Video Recording, Cornea physiopathology, Corneal Opacity physiopathology, Corneal Transplantation methods, Myopia physiopathology, Photorefractive Keratectomy methods
- Abstract
Background: Corneal barrier function following photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) was evaluated to determine corneal damage and to compare the amount of corneal trauma associated with haze development with the two procedures., Methods: The PRK and LASIK procedures were performed with the Nidek EC-5000 excimer laser. The Chiron Hansatome microkeratome was used in the LASIK procedures. We followed 1528 eyes of myopic patients (range, -1.00 to -23.00 D) classified into three groups according to age. Each group was divided into four subgroups depending on the amount of myopia (-1.00 to -2.75 D; -3.00 to -5.75 D; -6.00 to -9.75 D; -10.00 to -23.00 D). In eyes with haze formation, haze intensity and postoperative period of haze development were evaluated. The corneal uptake was 5.6 carbonfluorescein 5%, and a computer program analyzed video slit-lamp corneal images., Results: PRK and LASIK increased corneal permeability to fluorescein (2 to 8 weeks after PRK and 4 to 6 weeks after LASIK). Deeper ablations showed higher corneal fluorescein permeability for longer periods. In eyes with haze formation, an increased index of corneal fluorescein permeability was observed in the eyes with early postoperative haze formation (1 to 2 months) and a decreased index of corneal permeability was observed in eyes with late postoperative period haze formation (after 3 months). This finding suggests a difference in the haze that developed in the early and later postoperative periods. Fluorescein permeability after PRK returned to normal in 2 to 8 weeks and remained constant. Following LASIK, fluorescein permeability returned to normal in 4 to 6 weeks. Decreasing corneal permeability to fluorescein was observed 2 to 6 months after LASIK, and returned to normal at 6 months., Conclusion: Photorefractive surgery disrupts corneal barrier function for up to 6 months postoperatively, even though other clinical tests of the cornea may be normal. This finding may help explain some mechanisms of pathogenesis of complication development following PRK and LASIK. The fluorescein permeability findings demonstrated different mechanisms for early and late haze formation after PRK.
- Published
- 1999
- Full Text
- View/download PDF
11. [Objective indices of corneal transparency and of fluorescein permeability through the cornea before and after photorefractive keratectomy].
- Author
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Polunin GS, Kurenkov VV, Makarov IA, and Polunina EG
- Subjects
- Adolescent, Adult, Cornea surgery, Fluorophotometry statistics & numerical data, Humans, Hyperopia metabolism, Hyperopia surgery, Image Processing, Computer-Assisted, Lasers, Excimer, Middle Aged, Myopia metabolism, Myopia surgery, Permeability, Postoperative Period, Time Factors, Cornea metabolism, Fluoresceins pharmacokinetics, Fluorescent Dyes pharmacokinetics, Photorefractive Keratectomy
- Abstract
Video images of the cornea in photorefraction keratectomy (PFK) are analyzed by computer-aided microdensitometric analysis of televideo images of the eye. Optic density of various layers of the cornea and fluorescein penetration through the cornea were assessed in patients with myopia (235 eyes) and hypermetropia (65 eyes) before the after PFK. PFK was carried out by Nidek excimer laser (Japan). Analysis was carried out with consideration for the degree of emmetropia and patients' ages. Corneal transparency and index of fluorescein penetration through the cornea correlated with patient's age and emmetropia. Computer-aided microdensitometric analysis of televideo images of the eye earlier detects changes in the cornea than routine methods. The authors discuss the probability of assessing corneal transparency for selection of patients for PFK.
- Published
- 1998
12. Corneal transparency and measurement of corneal permeability in excimer laser photorefractive keratectomy.
- Author
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Polunin GS, Kourenkov VV, and Polunina EG
- Subjects
- Adult, Aqueous Humor metabolism, Biological Transport, Cornea surgery, Fluoresceins metabolism, Fluorescent Dyes metabolism, Fluorophotometry, Humans, Image Processing, Computer-Assisted methods, Lasers, Excimer, Middle Aged, Myopia surgery, Permeability, Cornea metabolism, Myopia metabolism, Photorefractive Keratectomy
- Abstract
Purpose: To introduce an image analysis of the cornea in photorefractive keratectomy (PRK) for preoperative and early postoperative determination of changes in the condition of the cornea., Methods: Slit-lamp videography was used to evaluate the cornea. Microdensitometry of the corneal images was performed. The optic density of the anterior, middle, and posterior corneal layers was measured. Photorefractive keratectomy was performed with the Nidek EC-5000 excimer laser. We followed patients with different amounts of myopia (range, -1.00 to -20.00 D) classified into three groups, according to age. Each age group was divided into four subgroups depending on the amount of myopia., Results: The analysis of the microdensitometry results of the optic section of transparent corneas in myopic patients demonstrated differences depending on age and mean amount of myopia. A correlation between the microdensitometric data of permeability by fluorescein and the refractive results of PRK was found., Conclusion: Quantitative image analysis of the cornea is a useful method to evaluate the condition of the cornea before and after PRK. This method can identify early damage to the cornea in myopia patients. Preoperative investigation of permeability of the cornea using fluorescein is an important method for selection of the patients for PRK.
- Published
- 1998
- Full Text
- View/download PDF
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