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2. Ultrasound Diagnosis of Clavicle Fractures in Newborns: A Systematic Review

Author

Luca Galimberti, Gisella Garbetta, Antonella Poloniato, Rosanna Rovelli, Graziano Barera, Nicola Guindani, and Maurizio De Pellegrin

Subjects
clavicle fractures, newborns, neonatal injuries, birth injuries, sonography, ultrasound, Pediatrics, RJ1-570
Abstract

Background: Fractures of the clavicle are the most common birth injury among newborns. Aim of this systematic review was to provide a comprehensive analysis of the role of ultrasound (US) in diagnosing clavicular fractures in neonates. Methods: A systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) using PubMed and Embase, including studies focusing on US in neonatal clavicle fracture. Age at US, number of cases examined by US and X-ray, US and X-ray diagnoses, US probe used, fracture site were systematically extracted. Results: A total of 231 articles were found. We ultimately selected 7 publications that satisfied the inclusion criteria, involving 136 patients examined between 3 days and 3 weeks of age, with 135 confirmed fractures. US was performed on all patients and correctly diagnosed all fractures (135/135, 100%). X-ray was performed on 94/136 patients (69.1%) and correctly diagnosed 89/93 fractures (95.7%). Fracture site was: medial in 2/79, middle in 37/79, and lateral in 40/79. In the remaining 57 cases, site was not reported. Conclusions: This review indicates that ultrasound is extremely reliable in diagnosing clavicle fractures in newborns and should be considered as the gold standard in this context.

Published
2024
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3. Expanding the spectrum of neonatal‐onset AIFM1‐associated disorders

Author

Alberto A. Zambon, Daniele Ghezzi, Cristina Baldoli, Gianni Cutillo, Katia Fontana, Valentina Sofia, Maria Grazia Patricelli, Alessia Nasca, Stefano Vinci, Ivana Spiga, Eleonora Lamantea, Giovanna F. Fanelli, Maria Grazia Natali Sora, Rosanna Rovelli, Antonella Poloniato, Paola Carrera, Massimo Filippi, and Graziano Barera

Subjects
Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429
Abstract

Abstract Objectives Pathogenic variants in AIFM1 have been associated with a wide spectrum of disorders, spanning from CMT4X to mitochondrial encephalopathy. Here we present a novel phenotype and review the existing literature on AIFM1‐related disorders. Methods We performed EEG recordings, brain MRI and MR Spectroscopy, metabolic screening, echocardiogram, clinical exome sequencing (CES) and family study. Effects of the variant were established on cultured fibroblasts from skin punch biopsy. Results The patient presented with drug‐resistant, electro‐clinical, multifocal seizures 6 h after birth. Brain MRI revealed prominent brain swelling of both hemispheres and widespread signal alteration in large part of the cortex and of the thalami, with sparing of the basal nuclei. CES analysis revealed the likely pathogenic variant c.5T>C; p.(Phe2Ser) in the AIFM1 gene. The affected amino acid residue is located in the mitochondrial targeting sequence. Functional studies on cultured fibroblast showed a clear reduction in AIFM1 protein amount and defective activities of respiratory chain complexes I, III and IV. No evidence of protein mislocalization or accumulation of precursor protein was observed. Riboflavin, Coenzyme Q10 and thiamine supplementation was therefore given. At 6 months of age, the patient exhibited microcephaly but did not experience any further deterioration. He is still fed orally and there is no evidence of muscle weakness or atrophy. Interpretation This is the first AIFM1 case associated with neonatal seizures and diffuse white matter involvement with relative sparing of basal ganglia, in the absence of clinical signs suggestive of myopathy or motor neuron disease.

Published
2023
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4. Corrigendum: Newborn screening for X-linked adrenoleukodystrophy in Italy: diagnostic algorithm and disease monitoring

Author

Eleonora Bonaventura, Luisella Alberti, Simona Lucchi, Laura Cappelletti, Salvatore Fazzone, Elisa Cattaneo, Matteo Bellini, Giana Izzo, Cecilia Parazzini, Alessandra Bosetti, Elisabetta Di Profio, Giulia Fiore, Matilde Ferrario, Chiara Mameli, Arianna Sangiorgio, Silvia Masnada, Gian Vincenzo Zuccotti, Pierangelo Veggiotti, Luigina Spaccini, Maria Iascone, Elvira Verduci, Cristina Cereda, Davide Tonduti, XALD-NBS Study Group, Gianluca Lista, Paola Fontana, Tiziana Varisco, Olivia Casati, Alberto Fabio Podestà, Maddalena Gibelli, Stefano Martinelli, Roberta Restelli, Laura Maria Pogliani, Roberta Agistri, Marco Giuseppe Nedbal, Paolo Vaglia, Chryssoula Tzialla, Luisa Magnani, Elena Sala, Laura Lorioli, Giuseppe Banderali, Diana Ghisleni, Bruno Drera, Marta Frittoli, Francesca Lizzoli, Marta Bellini, Paola Bruni, Ilaria Giulini, Valentina Benedetti, Valentina Polimeni, Nadia Salvoni, Masotina Raffaele, Cristina Bellan, Roberto Bottino, Graziano Barera, Antonella Poloniato, Marta Odoni, Ilaria Dalla Verde, Massimo Agosti, Angela Bossi, Anna Tosi, Anna Elisabetta Bussolini, Francesco Maria Risso, Vania Spinoni, Nicola Altamura, Patrizia Ballista, Silvia Di Chio, Luciana Pagani, Lidia Decembrino, Michela Grignani, Grazia Morandi, Valeria Angela Fasolato, Lorella Rossi, Emilio Palumbo, Alessandro Lepore, Maria Forestieri, Stefano Ghirardello, Elisa Civardi, Paolo Adamoli, Roberta Giacchero, Giovanni Traina, Patrizia Calzi, Fenesia Pedace, and Marco Sala

Subjects
X-ALD, X-linked adrenoleukodystrophy (X-ALD), Zellweger Spectrum Disorders, Aicardi-Goutières syndrome (AGS), hematopoietic stem cell transplantation (HCST), newborn screening (NBS), Neurology. Diseases of the nervous system, RC346-429
Published
2024
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5. Wisdom of the crowds forecasting the 2018 FIFA Men's World Cup

Author

Inácio, Marco Henrique de Almeida, Izbicki, Rafael, Lopes, Danilo Lourenço, Salasar, Luis Ernesto, Poloniato, João, and Diniz, Marcio Alves

Subjects
Statistics - Applications
Abstract

The FIFA Men's World Cup Tournament (WCT) is the most important football (soccer) competition, attracting worldwide attention. A popular practice among football fans in Brazil is to organize contests in which each participant informs guesses on the final score of each match. The participants are then ranked according to some scoring rule. Inspired by these contests, we created a website to hold an online contest, in which participants were asked for their probabilities on the outcomes of upcoming matches of the WCT. After each round of the tournament, the ranking of all users based on a proper scoring rule were published. This paper studies the performance of some methods intended to extract the wisdom of the crowds, which are aggregated forecasts that uses some or all of the forecasts available. The later methods are compared to simpler forecasting strategies as well as to statistical prediction models. Our findings corroborate the hypothesis that, at least for sporting events, the wisdom of the crowds offers a competitive forecasting strategy. Specifically, some of these strategies were able to achieve high scores in our contest.

Published
2020

7. Perinatal asphyxia and hypothermic treatment from the endocrine perspective

Author

Nicola Improda, Donatella Capalbo, Antonella Poloniato, Gisella Garbetta, Francesco Dituri, Laura Penta, Tommaso Aversa, Linda Sessa, Francesco Vierucci, Mariarosaria Cozzolino, Maria Cristina Vigone, Giulia Maria Tronconi, Marta del Pistoia, Laura Lucaccioni, Gerdi Tuli, Jessica Munarin, Daniele Tessaris, Luisa de Sanctis, and Mariacarolina Salerno

Subjects
perinatal asphyxia, hypothermic treatment, stress adaptations, endocrine sequelae, electrolytes disturbances, glucose abnormalities, Diseases of the endocrine glands. Clinical endocrinology, RC648-665
Abstract

IntroductionPerinatal asphyxia is one of the three most important causes of neonatal mortality and morbidity. Therapeutic hypothermia represents the standard treatment for infants with moderate-severe perinatal asphyxia, resulting in reduction in the mortality and major neurodevelopmental disability. So far, data in the literature focusing on the endocrine aspects of both asphyxia and hypothermia treatment at birth are scanty, and many aspects are still debated. Aim of this narrative review is to summarize the current knowledge regarding the short- and long-term effects of perinatal asphyxia and of hypothermia treatment on the endocrine system, thus providing suggestions for improving the management of asphyxiated children.ResultsInvolvement of the endocrine system (especially glucose and electrolyte disturbances, adrenal hemorrhage, non-thyroidal illness syndrome) can occur in a variable percentage of subjects with perinatal asphyxia, potentially affecting mortality as well as neurological outcome. Hypothermia may also affect endocrine homeostasis, leading to a decreased incidence of hypocalcemia and an increased risk of dilutional hyponatremia and hypercalcemia.ConclusionsMetabolic abnormalities in the context of perinatal asphyxia are important modifiable factors that may be associated with a worse outcome. Therefore, clinicians should be aware of the possible occurrence of endocrine complication, in order to establish appropriate screening protocols and allow timely treatment.

Published
2023
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8. Newborn screening for X-linked adrenoleukodystrophy in Italy: Diagnostic algorithm and disease monitoring

Author

Eleonora Bonaventura, Luisella Alberti, Simona Lucchi, Laura Cappelletti, Salvatore Fazzone, Elisa Cattaneo, Matteo Bellini, Giana Izzo, Cecilia Parazzini, Alessandra Bosetti, Elisabetta Di Profio, Giulia Fiore, Matilde Ferrario, Chiara Mameli, Arianna Sangiorgio, Silvia Masnada, Gian Vincenzo Zuccotti, Pierangelo Veggiotti, Luigina Spaccini, Maria Iascone, Elvira Verduci, Cristina Cereda, Davide Tonduti, XALD-NBS Study Group, Gianluca Lista, Paola Fontana, Tiziana Varisco, Olivia Casati, Alberto Fabio Podestà, Maddalena Gibelli, Stefano Martinelli, Roberta Restelli, Laura Maria Pogliani, Roberta Agistri, Marco Giuseppe Nedbal, Paolo Vaglia, Chryssoula Tzialla, Luisa Magnani, Elena Sala, Laura Lorioli, Giuseppe Banderali, Diana Ghisleni, Bruno Drera, Marta Frittoli, Francesca Lizzoli, Marta Bellini, Paola Bruni, Ilaria Giulini, Valentina Benedetti, Valentina Polimeni, Nadia Salvoni, Masotina Raffaele, Cristina Bellan, Roberto Bottino, Graziano Barera, Antonella Poloniato, Marta Odoni, Ilaria Dalla Verde, Massimo Agosti, Angela Bossi, Anna Tosi, Anna Elisabetta Bussolini, Francesco Maria Risso, Vania Spinoni, Nicola Altamura, Patrizia Ballista, Silvia Di Chio, Luciana Pagani, Lidia Decembrino, Michela Grignani, Grazia Morandi, Valeria Angela Fasolato, Lorella Rossi, Emilio Palumbo, Alessandro Lepore, Maria Forestieri, Stefano Ghirardello, Elisa Civardi, Paolo Adamoli, Roberta Giacchero, Giovanni Traina, Patrizia Calzi, Fenesia Pedace, and Marco Sala

Subjects
X-ALD, X-linked adrenoleukodystrophy (X-ALD), Zellweger Spectrum Disorders, Aicardi-Goutières syndrome (AGS), hematopoietic stem cell transplantation (HCST), newborn screening (NBS), Neurology. Diseases of the nervous system, RC346-429
Abstract

IntroductionX-linked adrenoleukodystrophy (X-ALD) is the most common inherited peroxisomal disorder caused by variants in the ABCD1 gene. The main phenotypes observed in men with X-ALD are primary adrenal insufficiency, adrenomyeloneuropathy, and cerebral ALD (cALD). Cerebral ALD consists of a demyelinating progressive cerebral white matter (WM) disease associated with rapid clinical decline and is fatal if left untreated. Hematopoietic stem cell transplantation is the standard treatment for cALD as it stabilizes WM degeneration when performed early in the disease. For this reason, early diagnosis is crucial, and several countries have already implemented their newborn screening programs (NBS) with the assessment of C26:0-lysophosphatidylcholine (C26:0-LPC) values as screening for X-ALD.MethodsIn June 2021, an Italian group in Lombardy launched a pilot study for the implementation of X-ALD in the Italian NBS program. A three-tiered approach was adopted, and it involved quantifying the values of C26:0-LPC and other metabolites in dried blood spots with FIA-MS/MS first, followed by the more specific ultra-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) technique and, finally, the genetic confirmation via focused NGS.DiscussionGenetically confirmed patients are set to undergo a follow-up protocol and are periodically evaluated to promptly start a specific treatment if and when the first signs of brain damage appear, as suggested by international guidelines. A specific disease monitoring protocol has been created based on literature data and personal direct experience.ConclusionThe primary aim of this study was to develop a model able to improve the early diagnosis and subsequent follow-up and timely treatment of X-ALD.EthicsThe study was approved by the local ethics committee. The research was conducted in the absence of any commercial or financial relationship that could be construed as a potential conflict of interest.

Published
2023
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9. Secondary infections in patients hospitalized with COVID-19: incidence and predictive factors

Author

Andolina, Andrea, Redaelli, Martina Baiardo, Bigai, Giorgia, Bigoloni, Alba, Borio, Giorgia, Bossolasco, Simona, Bruzzesi, Elena, Calabrò, Maria Grazia, Calvisi, Stefania, Campochiaro, Corrado, Canetti, Diana, Canti, Valentina, Castellani, Jacopo, Castiglioni, Barbara, Cavalli, Giulio, Cavallo, Ludovica, Cernuschi, Massimo, Chiurlo, Matteo, Cilla, Marta, Cinel, Elena, Cinque, Paola, Conte, Caterina, Da Prat, Valentina, Danise, Anna, De Lorenzo, Rebecca, Dell’Acqua, Antonio, Dell’Acqua, Raffaele, Della Torre, Emanuel, Della Torre, Liviana, Di Terlizzi, Gaetano, Dumea, Iulia, Farolfi, Federica, Ferrante, Marica, Frangi, Claudia, Fumagalli, Luca, Gallina, Gabriele, Germinario, Bruno, Gianotti, Nicola, Guffanti, Monica, Hasson, Hamid, Lalla, Francesca, Lanzillotta, Marco, Li Voti, Raffaele, Messina, Emanuela, Molinari, Chiara, Moizo, Elena, Montagna, Marco, Morsica, Giulia, Nozza, Silvia, Pascali, Maria, Patrizi, Alessandro, Pieri, Marina, Poloniato, Antonella, Prestifilippo, Dario, Ramirez, Giuseppe, Ranzenigo, Martina, Sapienza, Jacopo, Seghi, Federico, Tambussi, Giuseppe, Tassan Din, Chiara, Turi, Stefano, Uberti-Foppa, Caterina, Vinci, Concetta, Ripa, Marco, Galli, Laura, Poli, Andrea, Oltolini, Chiara, Spagnuolo, Vincenzo, Mastrangelo, Andrea, Muccini, Camilla, Monti, Giacomo, De Luca, Giacomo, Landoni, Giovanni, Dagna, Lorenzo, Clementi, Massimo, Rovere Querini, Patrizia, Ciceri, Fabio, Tresoldi, Moreno, Lazzarin, Adriano, Zangrillo, Alberto, Scarpellini, Paolo, and Castagna, Antonella

Published
2021
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12. Ultrasound Diagnosis of Clavicle Fractures in Newborns: A Systematic Review.

Author

Galimberti, Luca, Garbetta, Gisella, Poloniato, Antonella, Rovelli, Rosanna, Barera, Graziano, Guindani, Nicola, and De Pellegrin, Maurizio

Subjects
RISK assessment, MEDICAL information storage & retrieval systems, CLAVICLE fractures, DESCRIPTIVE statistics, SYSTEMATIC reviews, MEDLINE, ONLINE information services, CHILDREN
Abstract

Background: Fractures of the clavicle are the most common birth injury among newborns. Aim of this systematic review was to provide a comprehensive analysis of the role of ultrasound (US) in diagnosing clavicular fractures in neonates. Methods: A systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) using PubMed and Embase, including studies focusing on US in neonatal clavicle fracture. Age at US, number of cases examined by US and X-ray, US and X-ray diagnoses, US probe used, fracture site were systematically extracted. Results: A total of 231 articles were found. We ultimately selected 7 publications that satisfied the inclusion criteria, involving 136 patients examined between 3 days and 3 weeks of age, with 135 confirmed fractures. US was performed on all patients and correctly diagnosed all fractures (135/135, 100%). X-ray was performed on 94/136 patients (69.1%) and correctly diagnosed 89/93 fractures (95.7%). Fracture site was: medial in 2/79, middle in 37/79, and lateral in 40/79. In the remaining 57 cases, site was not reported. Conclusions: This review indicates that ultrasound is extremely reliable in diagnosing clavicle fractures in newborns and should be considered as the gold standard in this context. [ABSTRACT FROM AUTHOR]

Published
2024
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14. THE INFLUENCE OF THE RIB CAGE ON THE SEVERITY OF THORACIC SPINE BURST FRACTURES

Author

Rodrigo Arnold Tisot, Juliano Silveira Luiz Vieira, Diego da Silva Collares, Valci José Dapieve Junior, Leonardo Mota Schneider, Alexander Acauan de Aquino, Ana Victória Coletto Reichert, Augusto Poloniato Gelain, Isabelle Ranzolin, Jandáia Bortolini Marcon, Karine Dariva, Lucas Thomazi Ferron, Luiz Casemiro Krzyzaniak Grando, Matheus Henrique Benin Lima, and Rodrigo Alberton da Silva

Subjects
Spinal Fractures, Thoracic Vertebrae, Spinal Canal, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935
Abstract

ABSTRACT Objective: To analyze the anatomic influence of the ribs related to the severity of thoracic spine burst fractures. Methods: A retrospective review of 28 patients with thoracic spine burst fractures hospitalized by the Spine Group of the Hospital Ortopédico de Passo Fundo between January 2002 and December 2016 was conducted. The kyphosis, vertebral collapse, and narrowing of the vertebral canal measurements were compared between patients who had fractures at the true and false rib levels (T1 to T10) and those with fractures at the floating rib levels (T11 to T12). Results: The kyphosis, vertebral collapse, and narrowing of the vertebral canal values, measured only for vertebrae pertaining to the rib cage, were low. In addition, there were no statistically significant differences between the measurements of the group of patients with fractures at the level of the true and false ribs (T1 to T10) and the group of patients whose fractures were at the level of the floating ribs (T11 and T12). Conclusion: The differences between the traumatic structural changes in the vertebrae with true and false ribs (T1 to T10) and the vertebrae with floating ribs (T11 and T12) were not significant in the present study. Level of Evidence II; Retrospective study.

Published
2022
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15. I Congresso Sul Brasileiro Interligas do Aparelho Digestivo

Author

Pinto, Débora Mota, primary, Santos, Aléxia Oro dos, additional, Dein, Eduarda Pasini, additional, Kercher, Laura Chies, additional, Abdalla, Yasser Abrahao, additional, Coral, Roberto Pelegrini, additional, Souza, Letícia Faria de, additional, Chagas, Gabriel de Souza, additional, Oliveira, Pedro Afonso Alves de, additional, Santos, Mariusi Glasenapp dos, additional, Rodrigues, João Victor Cordeiro, additional, Fagundes, Daniella Soares, additional, Rocha, Josiane Santos Brant, additional, Ramos, Gabriela Piovezani, additional, Deus, Luciana Ampessan de, additional, Nóbrega, Heloísa Amaral Junqueira, additional, Cerutti, Elisandre Caroline dos Santos, additional, Ramos, Odery, additional, Lima, Maria Raquel da Silva, additional, Lima, Ana Lara Silva de, additional, Silva, Luiz Felipe Monteiro da, additional, Teles, Maria Camila, additional, Macedo, Olivana Silva Queiroz, additional, Paiva, Priscila Bernardo da Silva, additional, Ivo, Ivya da Silva, additional, Freitas, Ivanila de Sousa, additional, Saraiva, Mateus Fernandes, additional, Oliveira, Fernanda Pimentel de, additional, Nogueira, Maria Dinara de Araújo, additional, Ramos, Mariana Pereira, additional, Iepsen, Antonia Haigert, additional, Recuero, Amanda Medeiros, additional, Rosa, Miriam Richartz, additional, Petzhold, Luiza Esteves, additional, Brum, Nathalie Bordignon, additional, Furlanetto, Arthur, additional, Gatelli, Lucas Eduardo, additional, Kupski, Carlos, additional, Sousa, Andressa Mendes de, additional, Lopes, Layane Aiala de Sousa, additional, Geaquinto, Guilherme, additional, Batista, Estela Tebaldi, additional, Parizotto, Leise Herrmann, additional, Tiboni, Marcela, additional, Welter, Anna Carolina Hostins, additional, Kraemer, Douglas Rizzotto, additional, Sousa, Liliane Emilly dos Santos, additional, Leão-Cordeiro, Jacqueline Andréia Bernardes, additional, Silva, Antonio Márcio Teodoro Cordeiro, additional, Goulart, Marcela Ribeiro, additional, Ferreira, Gabriela Milhomem, additional, Poloniato, Luiz Felipe Castro Vaz, additional, Coutinho, Nívea Maria Carvalho, additional, Lopes, Pedro Augusto de Moraes, additional, and Pires, Marília Karolyne Dias, additional

Published
2021
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17. Urinary metabotypes of newborns with perinatal asphyxia undergoing therapeutic hypothermia.

Author

Enrico Valerio, Veronica Mardegan, Matteo Stocchero, Maria Elena Cavicchiolo, Paola Pirillo, Gabriele Poloniato, Gianluca D'Onofrio, Luca Bonadies, Giuseppe Giordano, and Eugenio Baraldi

Subjects
Medicine, Science
Abstract

Perinatal asphyxia (PA) still occurs in about three to five per 1,000 deliveries in developed countries; 20% of these infants show hypoxic-ischemic encephalopathy (HIE) on brain magnetic resonance imaging (MRI). The aim of our study was to apply metabolomic analysis to newborns undergoing therapeutic hypothermia (TH) after PA to identify a distinct metabotype associated with the development of HIE on brain MRI. We enrolled 53 infants born at >35 weeks of gestation with PA: 21 of them showed HIE on brain MRI (the "HIE" group), and 32 did not (the "no HIE" group). Urine samples were collected at 24, 48 and 72 hours of TH. Metabolomic data were acquired using high-resolution mass spectrometry and analyzed with univariate and multivariate methods. Considering the first urines collected during TH, untargeted analysis found 111 relevant predictors capable of discriminating between the two groups. Of 35 metabolites showing independent discriminatory power, four have been well characterized: L-alanine, Creatine, L-3-methylhistidine, and L-lysine. The first three relate to cellular energy metabolism; their involvement suggests a multimodal derangement of cellular energy metabolism during PA/HIE. In addition, seven other metabolites with a lower annotation level (proline betaine, L-prolyl-L-phenylalanine, 2-methyl-dodecanedioic acid, S-(2-methylpropionyl)-dihydrolipoamide-E, 2,6 dimethylheptanoyl carnitine, Octanoylglucuronide, 19-hydroxyandrost-4-ene-3,17-dione) showed biological consistency with the clinical picture of PA. Moreover, 4 annotated metabolites (L-lysine, L-3-methylhistidine, 2-methyl-dodecanedioic acid, S-(2-methylpropionyl)-dihydrolipoamide-E) retained a significant difference between the "HIE" and "no HIE" groups during all the TH treatment. Our analysis identified a distinct urinary metabotype associated with pathological findings on MRI, and discovered 2 putative markers (L-lysine, L-3-methylhistidine) which may be useful for identifying neonates at risk of developing HIE after PA.

Published
2022
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18. Pesquisas e Ações em Saúde Pública - Volume 2

Author

Santos, Maria Paula Bernardo dos, primary, Branco, Franciane Ferreira Maziero, additional, Fernandes, Jéssica Moreira, additional, Ferreira, Larissa Brazolotto, additional, Silva, Letícia Aparecida de Souza, additional, Silva, Luana Pereira da, additional, Lima, Lucas Satto de, additional, Nascimento, Mirela Martines do, additional, Fardin, Eduardo, additional, Poleto, Ana Paula, additional, Seganfredo, Afonso Alencar de Souza, additional, Lottici, Gabriel, additional, Burg, Maria Renita, additional, Silva, Leticia Aparecida de Souza, additional, Silva, Isabela Ramos da, additional, Lima, Maiara Matos, additional, Santos, Maria Paula Bernardo dos, additional, Catelan, Daniele, additional, Cardoso, Luiza Buchemi, additional, Menino, Ester Olívia de Oliveira, additional, Silva, Ítala Gouvêa, additional, Paula, Ana Beatriz Caldeira de, additional, Alessandretti, Mariana, additional, Andrade, Raquel Leite de, additional, Nunes, Fernanda Freire Campos, additional, Polay, João Pedro Gambetta, additional, Barth, Fabio Vinicius, additional, Cardoso, Bianca Cristina, additional, Castro, Ana Cristina Barth De, additional, Lima, Hailyn Ribas De, additional, Parlow, Jaqueline Meert, additional, Fonseca, Mariana, additional, Dalazoana, Elder, additional, Santos, Yasmim Brick, additional, Andrade, Luiz Henrique Vargas De, additional, Fernandes, Márcia A, additional, Magalhães, Juliana Macêdo, additional, Neta, Marly Marques Rêgo, additional, Sousa, Silvelene Carneiro De, additional, Ribeiro, Ítalo Arão Pereira, additional, Silva, Joyce Soares E, additional, Ribeiro, Amanda Alves de Alencar, additional, Fernandes, Márcia Astrês, additional, Rocha, Edna Monteiro, additional, Carvalho, Cláudia Maria Sousa de, additional, Ribeiro, Amanda Alves De Alencar, additional, Oliveira, Letícia Reis De, additional, Ferraz, Mônica Madeira Martins, additional, Araújo, Agostinho Antônio Cruz, additional, Santos, Letícia Viana dos, additional, Vilanova, Thâmara Beatriz Fernandes, additional, Santos, Lourenny Souza Dos, additional, Oliveira, Itana Nogueira De Araújo E, additional, Santos, Lourdes Beatriz Bispo Gonzaga, additional, Souza, Ana Clara Oliveira, additional, Uchôa, Lucas R, additional, Macedo, Raimundo Gierdson Abreu, additional, Rocha, Alexandre Fernando Rodrigues, additional, Oliveira, Lanielle de Sousa Brito, additional, Oliveira, Camila de Castro, additional, Santos, José M da S, additional, Oliveira, Gabriela Alves de, additional, Costa, Claylton de Abreu, additional, Rameiro, Iara Gabriele Lima, additional, Costa, Sidilene Pereira, additional, Sobrinho, Weberton Dorásio, additional, Loiola, Elissandra Ferreira, additional, Costa, Beatriz Campos, additional, Pacífico, Kassio dos Santos, additional, Oliveira, Maria Eduarda Ferreira de, additional, Marques, Gustavo Wenzel da Mata Monteiro, additional, Ferreira, Leonardo Gomes, additional, Souza, Esther Cardoso dos Santos, additional, Lima, Mariana Viandelli Correia, additional, Oliveira, Marcos Divino de, additional, Dias, Kamila Vieira, additional, Sampaio, Matheus Vieira, additional, Silva, Anita de Souza, additional, Mendonça, Karen Duanny Santos Barbosa, additional, Bispo, Elisa Maria Pacheco, additional, Varjão, Raiane Castor, additional, Oliveira, Linda Helena Jordão, additional, Nunes, Geyanna Dolores Lopes, additional, Campos, Roseane Nunes de Santana, additional, Schaffer, Débora Passos Hinojosa, additional, Sidrim, Gustavo Henrique Silva, additional, Coutinho, Maria Vitoria, additional, Modesto, Acsa Carvalho Andrade, additional, Coutinho, Lincon Manoel, additional, Silva, Wilson Santana, additional, Souza, Alice Ferreira Tomaz De, additional, Ferreira, Gabriella Lucas Da Cruz, additional, Caetano, Racquel Firpe, additional, Vilefort, Laís Assunção, additional, Oliveira, Mysma Vidal De, additional, Gonçalves, Andressa Simonassi, additional, Nascimento, Thayná Barbosa Do, additional, Silva, Laiane Cristina De Camargos, additional, Alves, Ana Eloísa Silva, additional, Carmo, Davi Fernandes Do, additional, Mello, Giovanna Galli Tonon De, additional, Coelho, Mateus Sampaio, additional, Gomes, Gabriela Somma, additional, Oliveira, Gabriely de, additional, Bertoldi, Gustavo Henrique Sumnienski, additional, Passos, Isabela de Araújo Belo, additional, Yamada, Isabela Yurie, additional, Rodrigues, Joanna Lara Castelo, additional, Frare, Letícia Elen Carpenedo, additional, Silva, Angel Adriany da, additional, Guerreiro, Milena Gonçalves, additional, Morioka, Mary, additional, Matos, Silvia Regina Seibel de, additional, Pinheiro, Sofia Landim Teixeirense, additional, Sales, Emilyn Vitória Brígido, additional, Passos, Danielle Cecato De Almeida, additional, Gois, Edson Santana, additional, Menezes, Ana Luiza Almeida, additional, Santos, Bruna Passos, additional, Melo, Bianca Santos, additional, Santos, Vitória Dias Dos, additional, Santos, Eduarda Lavínia Carneiro, additional, Santos, Beatriz Oliveira, additional, Melo, João Victor Santos, additional, Souza, Júllia Beatriz Araujo, additional, Nascimento, Leila Maria Lemos, additional, Medina, Mariana Sattler Lima, additional, Oliveira, Rosa Carolina Santos De, additional, Oliveira, Halley Ferraro, additional, Castro, Luana Fernandes Da Silva Oliveira, additional, Santos, Geovanna Godinho, additional, Dantas, Camila Flor, additional, Zoccoli, Thanyra Beatrice Vicentini, additional, Avelino, Thiago Dante Lustosa Da Rocha, additional, Macedo, Ana Clara Wimmer, additional, Fernandes, Fernanda Rodrigues Mangabeira, additional, Silva, Laura Teresa Lopes, additional, Vinhal, Letícia Dutra Magalhães, additional, Redígulo, Tayná Boldoni, additional, Ramsdorf, Maria Theresa De Alencar, additional, Lenhardt, Debora Giachini, additional, Pereira, Luiz Fernando Benazet De Assunção, additional, Oliveira, Camilla Haddad, additional, Souza, Kamilla Menezes E, additional, Silva, Letícia Angélica Da, additional, Silva, Pedro Henrique Fonseca Da, additional, Uehara, Gabriela Mayumi, additional, Castro, Luis Henrique Almeida, additional, Monteiro, Tiago Araújo, additional, Aguiar, Gladson Lopes De, additional, Oliveira, Erick Michell Bezerra, additional, Pinheiro, Marcos Vinicius Santos, additional, Jacinto, Izadora De Oliveira Almeida, additional, Araújo, Kassie Laís De Sousa, additional, Oliveira, Ianara Sousa De, additional, Silva, Ataianny Takira Galisa Da, additional, Braga, Bruna Letícia Martins, additional, Ferreira, Gabriela Milhomem, additional, Poloniato, Luiz Felipe Castro Vaz, additional, Rios, Mateus Felipe Batista, additional, Jacinto, Rafael Abrantes, additional, Jacinto, Rodrigo Abrantes, additional, Jacinto, Ruy Abrantes, additional, Luiz, Victoria Carolinne Alves, additional, Pires, Marília Karolyne Dias, additional, Calixto, Nicole Melo, additional, Fincatto, Yan, additional, Machry, Vanessa, additional, Souza, Amanda Grangeiro Martins de, additional, Giordani, Jéssica dos Santos, additional, Bonando, Bruno Matida, additional, Colacite, Jean, additional, Silva, João Felipe Tinto, additional, Filha, Francidalma Soares Sousa Cravalho, additional, Fukuda, Michelle Kaori Menezes, additional, Pereira, Adriana Jimenez, additional, Costa, Jardel Alves Da, additional, Barros, Francisco Douglas Dias, additional, Sousa, Lavínia Alves De, additional, Martins, Jorddam Almondes, additional, Moreira, Nádia K G, additional, Rego, Luara Da Silva, additional, Maciel, Karolina De Sousa, additional, Ferreira, Marcia De Sousa, additional, Alves, Letícia Alencar, additional, Gomes, Edna Lara Vasconcelos Da Silva, additional, Silva, Jéssica Ellen Alves Da, additional, Costa, Dayane Dayse De Melo, additional, Martins, Sâmia Karine De Moura, additional, Carvalho, Helinne Medeiros De, additional, Moreira, Iara Pereira Melo, additional, Pereira, Ana Rafaela Silva, additional, Pessoa, Márcia Luiza Dos Santos Beserra, additional, Barros, Nara Vanessa Dos Anjos, additional, Madeiro, Dandara Lucena Medeiros, additional, Pereira, Bárbara Camargo Da Rocha, additional, Fonseca, Caroline Antonia Gontijo Da, additional, Mourão, Felipe Nunes, additional, Dias, Jéssica Azevedo, additional, Miranda, Letícia Helena Braga, additional, Ferreira, Letícia Maria Possa Vicente Sacramento, additional, Gontijo, Luísa Teixeira Francisco E, additional, Costa, Maria Júlia Ribeiro da, additional, Castro, Luana Fernandes da Silva Oliveira, additional, Avelino, Thiago Dante Lustosa da Rocha, additional, Silva, Marielle Neiva Da, additional, Silva, Maira Luísa Neiva Da, additional, Lima, Mariana Schimming De, additional, Neves, Larissa Teixeira, additional, Goulart, Miguel Pereira, additional, Silva, Caroline Oliveira Da, additional, Souza, Matheus Alves De, additional, Gomes, Miriam Pardini, additional, Salvador, Louise De Oliveira, additional, Trentini, Allan Guilherme Alcântara, additional, Vieira, Cláudia Maria da Silva, additional, Ricarte, Kátia Magaly Pires, additional, Costa, Mara Jordana Magalhães, additional, Lages, Solange Ribeiro Nunes, additional, Monte, Aurinice Sampaio Irene, additional, Carneiro, José Alberto Lima, additional, Costa, Iaciara Silva, additional, Silva, Vanessa Soares Rocha da, additional, Ramos, Gustavo Ferreira, additional, Sousa, Jose Nilton Mendes de, additional, Corrêa, Alexsandra Carvalho de Araújo, additional, Nascimento, Isabel Rodrigues do, additional, Silva, Nayana Duarte da, additional, Santos, Edilson Lima dos, additional, Pellizzaro, André Olivo, additional, Bogoni, Bárbara, additional, Belini, Gabriela Fagan, additional, Zanella, Alana, additional, Zampieri, Giulia Parmeggiani, additional, Xavier, Laura Fernandes, additional, Nagata, Maiana Larissa De Castro, additional, Zanatta, Thamela Gazola, additional, Dacroce, Vitória Tischer, additional, Hristonof, Maria Lúcia Steiernagel, additional, Zanatta, Stefanie Flach, additional, Bertinatto, Ricardo Jean, additional, Xavier, Luiza Fernandes, additional, Ferrari, Gabriela Kreutz, additional, Scheibe, Victoria Machado, additional, Consoni, Paulo Roberto Cardoso, additional, Sousa, Julia Maria de Jesus, additional, Santos, Kelly Saraiva dos, additional, Louzeiro, Felipe Alves, additional, Dourado, Giovanna de Oliveira Libório, additional, Ribeiro, Emanuella Pereira, additional, Nunes, Yasmin de Souza, additional, Oliveira, Franscica Vitória de Souza, additional, Sousa, Eva Hadassa Cardoso de, additional, Paixão, Vitória Maria Sousa, additional, Oliveira, Fabíola da Costa, additional, Aguiar, Thalia Antônia Souza Nogueira Guerra, additional, Miranda, Eduarda da Silva, additional, Gomes, Bárbara Luiza Silva, additional, Fendler, Fernanda Santos, additional, Nonato, Gabrielle Celestrini, additional, Cotta, Marcelo Araújo Lacerda, additional, Pinto, Maria Eduarda Papini de Magalhães, additional, Almeida, Nicolle Mendes de, additional, Couto, Bráulio Roberto Gonçalves Marinho, additional, Ferreira, Barbara Quinteiro, additional, Gomes, Rodrigo Da Silva, additional, FERREIRA, MAÍRA LUCÍLIA MONTEIRO, additional, Freitas, Kaio Gomes de, additional, Castralli, Heloísa Augusta, additional, Pires, Catarina Amorim Baccarini, additional, Moraes, Tatiane Dunder de, additional, Calumby, Laís Leão, additional, Roriz, Mariana Romão, additional, Diniz, Clara da Glória, additional, Lima, Sarah Kelly Bessa de, additional, CORRÊA, ANA PAULA EMERICK, additional, Pereira, Jordanio Dos Reis, additional, Araújo, Poliana De Queroz De, additional, Santos, Joel Silva Dos, additional, Veira, Stenio Da Silva, additional, Matias, Julia de Oliveira, additional, Nascimento, Brunna Stella Vieira do, additional, Pinho, Jaqueline Fagundes Carvalho Brito do, additional, Pereira, Jordania Kethlen Campos, additional, Morais, José Sérgio Franco Rocha de, additional, Santos, Tiago Ramos dos, additional, Haddad, Yasmin de Alcântara e Silva, additional, Tigre, Wecsley Ferreira, additional, Saldanha, Janaína Cláudia da Silva, additional, Peixoto, Stefany Monteiro, additional, PEREIRA, MIRIAN GABRIELA MARTINS, additional, Nascimento, Luana, additional, TEIXEIRA, THULIO CESAR, additional, CARNEIRO, GUSTAVO NETTO DO CARMO, additional, Carneiro, João Gabriel Rodrigues, additional, FARIA, MATHEUS CAMELO FERREIRA, additional, Azevedo, Danyelly Rodrigues Machado, additional, Sinimbu, Amália de Jesus Moura, additional, Alves, Ana Angélica, additional, Nascimento, Cidianna Emanuelly Melo do, additional, Dantas, Mariana Peixoto, additional, Silva, Maria Fernanda Oliveira da, additional, Rodrigues, João Victor Campelo Lima, additional, Batista, Matheus Alexandre Sobral, additional, Anchieta, Ana Luísa Teófilo, additional, Santos, Rosana Serejo dos, additional, Queiroz, Solange Cristina Ferreira De, additional, Dias, Alice Pereira, additional, Pereira, Ana Karina Viana, additional, Lira, Letície Batista, additional, Santos, Valdeane Silva, additional, Mendes, Makellyne da Costa, additional, Castro, Idaiane Ribeiro Dias, additional, Alves, Wendel Marcos, additional, Rodrigues, Caroline Souza, additional, Martins, Maria Eduarda Araújo, additional, Cipriano, Camila Lima Sousa, additional, Torres, Luana Cavalcante Mariano Calixto, additional, Lopes, Glória Maria de Almeida, additional, Meireles, Jéssica Karolyne Feitosa Melo, additional, Machado, Paula Rafaela Gomes, additional, Gomes, Leonardo Bezerra, additional, Andrade, Matheus Lima, additional, Castelo, Jéssica Teixeira, additional, Monteiro, Cacilia Uchoa, additional, Martins, Ana Raquel Araújo, additional, Dias, Francisco Ricardo Barreto, additional, Coelho, Amanda Marques, additional, Cavassola, Davidson de Lima, additional, Costa, Giovanna de Carvalho Meneses, additional, Brito, Lizandra Azevedo, additional, Oliveira, Leonam Costa, additional, Zanella, Pedro Luís Ávila, additional, Grilo, Rafael Santana, additional, Faria, Rodrigo Ferreira, additional, Toledo, Antônio Homero Rocha, additional, Barra, Carolina Mark Wu Vitorino, additional, Boechat, Esther Pifano, additional, Nogueira, Lyandra Yuri Katsuyama, additional, Monteiro, Isabela Costa, additional, Prudente, Ana Luiza Naves, additional, Carneiro, Júlia Fonseca, additional, Crispim, Ana Clara Ferreira, additional, Freire, Pedro Vitor Vieira, additional, Uchôa, João Bruno Machado, additional, Silva, Clécia Maria Da, additional, Silva, Jamyne Victorya Figueredo Da, additional, Barros, Fátima Rosane, additional, Rocha, Rute Emanuela Da, additional, Silva, Tamiris Ramos, additional, Soares, Tiago, additional, Nolêto, Sâmyla Bruno, additional, Duarte, Larissa Da Silva, additional, Magalhães, Kamila Fernanda Soares, additional, Alves, Ana Glécia Pimentel, additional, Carvalho, Helline Medeiros De, additional, Macedo, Mikaella Isis De, additional, Rocha, Lucineide De Brito, additional, Chaves, André F De C P, additional, Almeida, Priscilla Dantas, additional, Nunes, Rômulo Veloso, additional, Araújo, Telma Maria Evangelista de, additional, Fronteira, Inês, additional, Sousa, Mauricelia P de, additional, Castro, Gabrielle Batista Silva, additional, Dias, Josimar Kapps de Souza, additional, Fronza, Murilo Elias, additional, Rossi, Arthur Proença, additional, COSTELLA, GISELI, additional, Leon, Cristiano De, additional, EVARISTO, ALMIRO SAGÁS, additional, Gonçalves, Emília Samara Mariano, additional, Lourenço, Lourena Gouveia, additional, Kapps, Josimar, additional, COSTA, LUIZA GABRIELA, additional, Bastos, Ana Carolina da Silva, additional, Melo, Marcos André Lima, additional, Costella, Giseli, additional, Lamonica, Gabriela Guilhoto Cabral, additional, Mello, Rafaela da Silva Vieira de, additional, Azevedo, Juliana Latini, additional, Valladares, Ana Luíza de Sousa, additional, Santos, Bárbara Aparecida Costa, additional, Cajazeira, Brenda Carolina Rodrigues, additional, Libanio, Gabriela Cristina, additional, Gonçalves, Tatiane da Cunha Marques, additional, Bacha, Felipe Lage, additional, Rodrigues, Fernanda Diniz, additional, Carvalho, Gabriela Dantas, additional, Arruda, Francisco Lázaro, additional, Silva, Paulo Romão Ribeiro Da, additional, Freitas, Guilherme Barroso Langoni De, additional, Santos, Rebeca Muálem De Moraes, additional, OLIVEIRA, Guilherme Rodrigues, additional, Leal, Ana Carolina Cunha, additional, FREITAS-SILVA, Ana Letícia, additional, GUIMARÃES, Vinícius Henrique Almeida, additional, NUNES, Luís Gustavo Fagundes, additional, Aguiar, Vanessa de, additional, Schiavetto, Igor Marques, additional, Fraga, Gustavo Pereira, additional, Calderan, Thiago Rodrigues Araújo, additional, Souza, Hellen Soraya de Brito, additional, Barros, Cassandra Mirtes De Andrade Rêgo, additional, Vieira, Danilo Silva, additional, Barros, Ingrid Cristina Rêgo, additional, Barros, Marcos Aurélio Lima, additional, Pereira, Bianca de Fátima, additional, Rodrigues, Cátia Ribeiro de Sá, additional, Rodrigues, João Pedro Torres Neiva, additional, Terror, Mariana Sequetto, additional, Aguiar, Pedro Henrique Chaves Souza, additional, Torres, Raquel Vieira, additional, Oliveira, Tiago de Jesus, additional, Oliveira, Mariana Constantina de, additional, Brandão, Socorro Adriane de S Meneses, additional, Rodrigues, Érica De Alencar, additional, Magalhães, Edilane Jales Leite, additional, Ramos, Carmen Viana, additional, Ribeiro, Ivonizete Pires, additional, Martins, Maria do Carmo de Carvalho e, additional, Lago, Eliana Campêlo, additional, Feitosa, Lucíola Galvão Gondim Corrêa, additional, Costa, Polyana Felipe Ferreira da, additional, Costa, Willams Araujo Da, additional, Andrade, Ingrid Sousa, additional, Miranda, Paulo Henrique Soares, additional, Santos, Paulo Ion Feitosa, additional, Silva, Stefane Gonçalves, additional, Santana, Jackline Pinheiro Santos, additional, Grangeiro, Iara Miranda, additional, Coutinho, Rosana de Jesus Santos Martins, additional, and Albuquerque, Ingrid de Campos, additional

Published
2021
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20. Suplementação antioxidante aguda e prevenção de dano lipídico e muscular de ciclistas em prova de longa duração: estudo experimental

Author

Luiz Casemiro Krzyzaniak Grando, Augusto Poloniato Gelain, Marcela Cararo, Camila Gatto, Thaís Pasqualli, and Luciano de Oliveira Siqueira

Subjects
Antioxidantes, Suplementos Nutricionais, Ciclismo, treinamento aeróbico, Sports, GV557-1198.995
Abstract

Introdução: A transição epidemiológica e demográfica, o sedentarismo e o estímulo ao desenvolvimento de atividades físicas regulares sem a devida orientação de profissionais podem estar relacionados a distúrbios osteoarticulares e musculares. Objetivo: Analisar o efeito da suplementação de vitamina E (α-tocoferol), vitamina C (ácido ascórbico) e ácido graxo Ômega 3 no dano oxidativo de 20 atletas masculinos em uma prova de ciclismo de longa duração. Métodos: Realizou-se um estudo clínico randomizado de 20 atletas participantes de uma prova de ciclismo de 200 km. Resultados: O grupo suplementado apresentou uma menor dano lipídico (redução de TBARS p

Published
2021
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21. Saúde do Ensino à Pesquisa - Volume 1

Author

BRENNER, Augusto Madke, primary, GONZATTI, Carolina, additional, NESELLO, Alberto Chitolina, additional, FURTUNATO, Luis Fillipy, additional, ELVIR, Francisco Alfonso Rodriguez, additional, ROCHA, Naise Oliveira da, additional, ARAÚJO, Abelardo de Queiroz Campos, additional, TORRES, Paloma Ribeiro, additional, SANTOS, Roseli dos, additional, PAIVA, Eliane de Souza, additional, BACELO, Adriana Costa, additional, SILVA, Carlos Eduardo da, additional, ARAÚJO, Isabelle Cássia Viana de, additional, Mota, Aline Carolina Castro, additional, SANTOS, Eliete Viana dos, additional, ALVES, João Victor Moura, additional, MORAES, Joel Campos de, additional, ALVES, Krisnna Mariana Aranda, additional, DANTAS, Alison Rener Araujo, additional, DIAS, Filipe Pereira da Silva, additional, BARROSO, Maria Nadiana Veríssimo, additional, SOUSA, Viviane Fernandes de, additional, OLIVEIRA, Rafaela Rolim de, additional, BATISTA, Jessika Lopes Figueiredo Pereira, additional, ALMEIDA, Hélida Maravilha Dantas e Sousa, additional, RAMOS, Ana Cecília Alexandre dos, additional, NASCIMENTO, Arydyjany Gonçalves, additional, CHAVES, Bruno Freire Braun, additional, BATISTA, Jéssika Lopes Figueiredo Pereira, additional, SILVA, Jislene dos Santos, additional, TORRES, Barbara Vitória dos Santos, additional, ALMEIDA, Lindynês Amorim de, additional, SILVA, Rillary Caroline de Melo, additional, VIEIRA, Ana Carolina Santana, additional, GOMES, Jéssica da Cruz, additional, PEREIRA, Luana Mendes, additional, BRAGA, Iasmyn dos Santos, additional, FERNANDES, Diégina Araújo, additional, FERREIRA, Maria Denise Leite, additional, CAVALCANTI, Élida Batista Vieira Sousa, additional, BARROS, Monique Emanuela Frutuoso Xavier, additional, PESSOA, Matheus Marley Bezerra, additional, TAVARES, Josean Fechine, additional, BATISTA, Leônia Maria, additional, DANTAS, Alison Rener Araújo, additional, CASIMIRO, Maria Raquel Antunes, additional, TORRES, Iara Carlin, additional, ARAUJO, Isabela de Oliveira, additional, OLIVEIRA, Jonas Munck de, additional, COSTA, Rafaella Angélica Vieira e Silva, additional, SILVA, Yara Mendes, additional, TEIXEIRA, Maria Teresa Bustamante, additional, FRANCO, Mariana Godinho, additional, VICENTINE, Albeliggia Barroso, additional, EVERLING, Matheus Dalla Barba, additional, TUON, Alicia Silveira, additional, CATÃO, Juliana Rossi, additional, DEBASTIANI, Mariana Severo, additional, KO, Tereza, additional, SOARES, Anne Caroline Frota, additional, MAIA, Isabela Mendes, additional, SIQUEIRA, José Matheus Macêdo Torquato de, additional, MARQUES, Paulo Victor Amorim, additional, GREGORY, Gabriela, additional, VOLPI, Luiza Mattos, additional, BIRCK, Martina Souilljee, additional, KUIAVA, Victor Antonio, additional, PIOVESAN, Fabiana, additional, KURMANN, Ana Claudia, additional, GELAIN, Augusto Poloniato, additional, LUBBE, Mariana Mesko da Fonseca, additional, VOGT, Natália Sbaraini, additional, MARTIO, Thamyze Mânica, additional, POLLI, Fernanda Raquel, additional, LUI, Jéssica Maldaner, additional, SURKAMP, Nicolle, additional, POLLETTO, Pedro Henrique Menegaz, additional, OLIVEIRA, Lucas Donato Simão de, additional, AYRES, André Marques da Nóbrega, additional, AYRES, Aryana Marques da Nóbrega, additional, COSTA, Lorena Brasil, additional, TELINO, Manuella Ferreira Leal, additional, MEDEIROS, Tibério Batista de, additional, SIMÕES, Rachel Siqueira de Queiroz, additional, FONSECA, Ana Luísa Scafura da, additional, CARVALHO, Ana Luíza de Castro, additional, SILVA, Gabriela Ferreira da, additional, BRESSER, Matheus, additional, MARTINS, Vinícius Cordeiro, additional, ALMEIDA, Maria José Guedes Gondim, additional, LIRA, Rafaelle Cavalcante de, additional, CALIXTO, Anna Valéria Duarte, additional, SOUZA, José Vinícius de, additional, FERREIRA, Mateus Andrade, additional, ANDRADE, José Isaac Alves de, additional, SOUSA, Milena Nunes Alves de, additional, FREIRE, Eder Almeida, additional, DIAS, Luiz Gabriel Atanásio, additional, SILVEIRA, Maria Laryssa Monte da, additional, CAVALCANTI, Raquel Fragoso Pereira, additional, ASSIS, Luciana Moura de, additional, ALMEIDA, Lícia Maria Belchior, additional, TAVARES, Maryanne Sousa, additional, BELCHIOR, Luciana Dias, additional, Duarte, Israel dos Santos, additional, ARNAUD, José Roberto Santos, additional, PERÔNICO, Filipe Mesquita, additional, LIMA, Marcos Silva de, additional, NASCIMENTO, Letícia Queiróz Dias do, additional, CAVALCANTI, Gustavo Henrique de Góes, additional, MOURA, Ludmila Sandy Alves, additional, CHAVES, Maria Luíza Braga de Castro, additional, FEITOSA, Ráira Thiele Ribeiro, additional, CORDEIRO, Lúcia Helena de Oliveira, additional, SINEZIO, Palloma Rayane Alves de Oliveira, additional, NUNES, Maria Jussara de Medeiros, additional, CAVALCANTE, Maria Karoline Silveira, additional, NOGUEIRA, Érika Fernandes da Silva, additional, MORAIS, Maria Cleide Araújo de Medeiros, additional, FERNANDES, Suzana Carneiro de Azevedo, additional, MARTINS, Renata Renó, additional, MARTINS, Renan Renó, additional, GONÇALVES, Maria Teresa Renó, additional, PAIVA, Artur Diogenes Pinheiro, additional, CASTRO, Diego Amaral de Miranda, additional, Macêdo, Joricene Soares de, additional, LOPES, Rafael Menezes, additional, ROCHA, Lays, additional, ARAÚJO-FILHO, Jorge Luiz Silva, additional, SANTOS, Ewelyn Cintya Felipe dos, additional, MACHADO, Janaína Carla Barbosa, additional, FERREIRA, Magda Rhayanny Assunção, additional, SOARES, Luiz Alberto Lira, additional, OLIVEIRA, Patrícia Rosa de, additional, ANHOLETO, Luís Adriano, additional, CONTIERO, Jonas, additional, ROCHA, Cláudia Quintino da, additional, MONTEIRO, Odair dos Santos, additional, CAMARGO-MATHIAS, Maria Izabel, additional, GUIMARÃES, Vinícius Henrique Almeida, additional, CASSIANO, Carolina, additional, SILVA, Júlia Neves Batista, additional, SOARES, Thomas de Matos, additional, GARCIA, Mariana Franc, additional, CREMA, Eduardo, additional, DANTAS, Jéssica Maria Palmeira, additional, NOBRE, Stefane Vieira, additional, Silva, Rui Santana, additional, SILVA, Mikaelle Ysis da, additional, PINTO, Antonio Germane Alves, additional, Silva, José Adelmo da, additional, SCHMIDT, Letícia Carreiro, additional, FREITAS, Felipe Teixeira, additional, DIAS, Juliana Lopes, additional, MAGRANI, Gefson Couto, additional, REIS, Bruno Cezario Costa, additional, SILVA, Patrícia de Cássia Neri Beraldo, additional, FREITAS, Héverton Barbosa de, additional, MENDONÇA, Adriana Rodrigues dos Anjos, additional, FALCÃO, Camila Oliveira, additional, OLIVEIRA, Maria Paula Carneiro de Brito, additional, CAVALCANTE-SILVA, Luiz Henrique Agra, additional, PIRES, Andressa Cavalcanti, additional, MOURA, Anne Vitória Vieira de Medeiros, additional, CAVALCANTI, Amanda de Souza, additional, NETTO, Beatriz Andrade de Lima, additional, SILVA, Manoela Silvestre Vieira da, additional, SILVA, Rafael Silvestre Vieira da, additional, PAIVA, Artur Diógenes Pinheiro, additional, Araújo, Jorge Luiz Silva, additional, MAROJA, Karolynne Augusta Bezerra, additional, SILVA, Athyllas Aparecido Ferreira da, additional, MENEZES, Débora Maggy Pessoa de, additional, LOPES, Gabriela da Silva, additional, GONÇALVES, Thauany dos Santos, additional, CARNEIRO, Miriam Lúcia da Nóbrega, additional, VELOZO, Tatiane, additional, Tamburús, Murilo Luiz Soares, additional, LAIA, Marcella Gonçalves de, additional, FREITAS-SILVA, Ana Letícia, additional, OLIVEIRA, Guilherme Rodrigues, additional, NUNES, Luís Gustavo Fagundes, additional, PORTELA-DE-SÁ, Heloisa Helena Pessoa, additional, GOTTARDI, Giovanna Pellegrino, additional, REIS, Mariana Carla Marques Dos, additional, COSTA, André Silva, additional, FREITAS, Paula Alexandre, additional, OLIVEIRA, Keciany Alves de, additional, TACCONI, Carolina Maria Novais Caires, additional, SILVA, Heliane Formagio, additional, Cardoso, Normandis, additional, SILVA, Roger Rodrigues da, additional, ALVES, Maria do Socorro Oliveira, additional, SILVA, José Adelmo da, additional, PEREIRA, Rafael da Silva, additional, LIMA, Ainoã de Oliveira de, additional, GOMES, Samara Calixto, additional, HONORATO, Monalisa Alexandre, additional, MENDONÇA, Clara Maria Sousa, additional, FERREIRA, Beatriz Nayanne Machado da Silva, additional, FONSECA, Rachel Cavalcanti, additional, SILVA, Ewilleny Galdino da, additional, TAVARES, Natália Bastos Ferreira, additional, LIMA, Luzenir Alves de, additional, BRAGA, Douglas Vieira, additional, SANTOS, Lucas Sued Azevedo, additional, LISBOA, Maria Luisa Lima, additional, CASTRO, Valéria Leal Mathias, additional, COSTAS, Adriele Santos, additional, CARVALHO, Iris Silva, additional, RODRIGUES, Ana Paula Mendes, additional, BATISTA, Aldair Almeida, additional, LOURES, Geovane Almeida, additional, MOTA, Raquel Cristina Lucas, additional, FREITAS, Emerson Belarmino de, additional, SILVA, George Marques Fernandes da, additional, ARAÚJO, Glenda Yohana Maria do Nascimento Pereira de, additional, ASSUNÇÃO, Jéssica Andressa de Oliveira, additional, MACEDO, Lays Trajano de, additional, AIRES, Iasmin Gondim do Nascimento, additional, FERREIRA, Gabriela de Oliveira, additional, ARAÚJO, Diego Igor Alves Fernandes de, additional, SOUSA, Vagner Alexandre de, additional, FERNANDES, Anny Palloma de Lima Arruda, additional, ARAÚJO, Priscylla Rayama Alves Fernandes de, additional, SANTOS, Samuel Brito Ferreira, additional, PINHEIRO, Anderson Angel Vieira, additional, OLIVEIRA, Matheus Donato Simão de, additional, and RAMOS, Alberto José Correia, additional

Published
2020
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22. Coronavirus Disease 2019 in Recipient of Allogeneic Hematopoietic Stem Cell Transplantation: Life-threatening Features Within the Early Post-engraftment Phase

Author

Chiara Oltolini, Anna Guidetti, Marco Ripa, Barbara Castiglioni, Chiara Tassan Din, Sara Mastaglio, Diana Canetti, Giacomo Monti, Andrea Andolina, Chiara Molinari, Antonella Poloniato, Andrea Mastrangelo, Marica Ferrante, Marco Lanzillotta, Paolo Scarpellini, Antonella Castagna, Paolo Corradini, and Fabio Ciceri

Subjects
Diseases of the blood and blood-forming organs, RC633-647.5
Published
2020
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23. PERFIL CLÍNICO-EPIDEMIOLÓGICO DA SONOLÊNCIA DIURNA EXCESSIVA QUANTO A SUA AVALIAÇÃO POR INTERMÉDIO DA APLICAÇÃO DE ESCALAS SUBJETIVAS DO SONO: ESCALA DE SONOLÊNCIA DE EPWORTH E ÍNDICE DE QUALIDADE DO SONO DE PITTSBURGH

Author

Hugo Leonardo Shigenaga Ribeiro, Vergílio Pereira Carvalho, Adriane Cristiane Mesquita Petruco, Luiz Eduardo Bersani-Amado, Waldemar Naves do Amaral, Jair Pereira de Melo Júnior, Lilian Martins Lacerda, Thays Barbieri Poloniato, Marina Luana Silva Carneiro, Carolina Leão de Moraes, Fernarda Sardinha de Abreu Tacon, Irumuara Interaminense Uliana Filho, Laura Divina Souza Soares, and Marcelo Aguilar Puzzi

Subjects
Sono, Sonolência, Transtornos da Sonolência Excessiva, Biology (General), QH301-705.5, Nursing, RT1-120
Abstract

Infere-se que muitas pesquisas comprovam o papel de vários fatores de saúde, estilo de vida e doenças na expressão da sonolência diurna excessiva. O presente estudo teve por objetivo demonstrar o perfil clínico-epidemiológico da sonolência diurna excessiva com base nos seus achados na literatura mediante aplicação de duas escalas subjetivas utilizadas em protocolos de pesquisa e centros de avaliação do sono, são elas: a Escala de Sonolência de Epworth e Índice de Qualidade do Sono de Pittsburgh. Trata-se de uma revisão bibliográfica, em que foram elegíveis artigos primários, com data de publicação de 1999 até 2018, em que se utilizou as seguintes bases de dados referenciais: Biblioteca Virtual de Saúde (Bvs), Web of Science; Periódico da Capes; Scopus; SciELO; Social Science Research Network (SSRN); PubMed; LILACS e MEDLINE Complete. Na seleção crítica dos artigos de estudos transversais, recorreu-se à Appraisal tool for Cross-Sectional Studies (AXIS). Verificou-se que medidas autorrelatadas são prontamente obtidas com questionários validados como a Escala de Epworth (ESS) e Pittsburgh Sleep Quality Index (PSQI). Outrossim, a literatura evidencia a relevância da análise e diagnóstico da sonolência diurna excessiva mediante o uso de exames eletrofisiológicos incluindo videopolissonografia noturna, teste de latências múltiplas do sono, teste de manutenção da vigília e actigrafia. A fadiga foi relacionada à depressão, à ansiedade e à qualidade do sono, mas não a sonolência diurna excessiva. Por último, indivíduos obesos, quando operados pela cirurgia metabólica pela técnica de desvio biliopancreático apresentaram normalização da sonolência diurna excessiva.

Published
2020

24. Avaliação da qualidade de vida de médicos clínicos e cirurgiões

Author

Hugo Machado Sanchez, Andre Luiz Sbroggio Junior, Eliane Gouveia de Morais, Patricia Leão da Silva Agostinho, Thays Barbieri Poloniato, and Paulo Grossi Soares

Subjects
Qualidade de vida, Médicos, Equilíbrio Trabalho-Vida, Saúde do Trabalhador, Medicine (General), R5-920, Public aspects of medicine, RA1-1270
Abstract

Objetivo: Avaliar a qualidade de vida (QV) dos profissionais da área médica de acordo com a especialidade escolhida (clínica ou cirúrgica). Métodos: Estudo transversal analítico, realizado em 2016, com médicos de clínicas e hospitais de Rio Verde, Goiás, Brasil. Utilizaram-se dois questionários: um sobre aspectos sociodemográficos e outro para avaliação da QV, o World Health Organization Quality of Life-Bref (WHOQOL-abreviado). Entregaram-se 287 questionários, sendo 144 respondidos. Dados comparativos dos domínios receberam análise ANOVA, MANOVA, MANCOVA, correlação de Pearson e regressão linear, considerando-se p˂0,05. Resultados: Encontrou-se média de idade de 37,7±10,09 anos e a maioria do sexo masculino (63,1%; n=91). O domínio físico foi, significantemente, melhor avaliado nos valores médios de QV pelo sexo masculino (p=0,002), assim como o domínio meio ambiente (p=0,031). Quando se comparou valores médios da QV e seus domínios de acordo com a atuação clínica e/ou cirúrgica dos médicos, não houve diferença significativa. Ao se comparar médicos plantonistas e não plantonistas, verificou-se que os domínios relação social (p=0,049), meio ambiente (p=0,001) e QV (p=0,024), independentes da carga horária, apresentaram piora no caso dos médicos plantonistas. Quanto maior o tempo de formado, maior a percepção do domínio meio ambiente (p=0,02). Sem diferença significativa quanto à faixa salarial. Conclusão: Não houve diferença na qualidade de vida global entre os médicos clínicos e cirurgiões avaliados, porém, quando comparado entre o sexo, o masculino obteve desempenho mais satisfatório nos domínios físico e meio ambiente. Evidenciou-se que a faixa salarial não influencia na qualidade de vida desses profissionais.

Published
2018
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25. Performance da CO-oximetria de pulso para identificação do tabagismo na Atenção Básica

Author

José Laerte Rodrigues Silva Júnior, Marina do Carmo Rodrigues, Ana Carolina Poloniato Brito, Fernando Conforti Prudente, Iassiminy Santos Merhi, Gabriela Ferreira Leandro de Oliveira, Mirella Mezzomo Zamboni, Daniel Silva Lôbo, Winston Andrade Almeida, Luiza Ferreira Rocha, and Guilherme Peixoto Nascimento

Subjects
Smoking habit, Carboxyhemoglobin, Primary Health Care., Education, Medicine (General), R5-920
Abstract

Objective: To evaluate the performance of a CO-oximeter to determine the smoking status in relation to an exhaled carbon monoxide meter in subjects attending Primary Health Care. Methods: A cross-sectional study was carried out in outpatients aged 18 years or older, attending Primary Health Care Units of Anápolis-GO. Subjects were submitted to clinical evaluation, exhaled carbon monoxide dosing, and carbon monoxide measurement by pulse CO-oximetry. Results: A total of 449 individuals were included, 106 smokers (23.6%), 89 ex-smokers (19.8%), 203 never smokers (45.2%) and 51 passive smokers (11.4%). CO-oximetry with cutoff point of ≥4% showed a specificity of 77.3% (95% CI 72.5% -81.6%), a sensitivity of 52.8% (CI 95% 42.9% - 62,6%), positive and negative predictive values of 45.3% (95% CI: 38.9% -51.9%), 82.1% (95% CI: 78.8% -85%), respectively and area under ROC curve of 0.73 (95% CI 0.67-0.78). The exhaled carbon monoxide dosage with cut-off point of ≥5ppm showed a specificity of 96.2% (95% CI 93.6% -98%), sensitivity of 79.2% (95% CI 70.3% -86, 5%), positive and negative predictive value of 88.2% (95% CI 81.3% -92.8%), 92.9% (95% CI 89.9% -95%), respectively, and area under ROC curve of 0.91 (95% CI 0.87-0.95). COHb(%) ≥4 showed OR: 4.3; (95%CI 2.7-7.1); p

Published
2018
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26. Esôfago de Barret: Diagnóstico e Manejo

Author

Poloniato, Luiz Felipe Castro Vaz, primary, Oliveira, Gabriel Gonçalves Rezende, additional, França, Hiago Vinícius de, additional, Cunha, Renan Rodrigues de Oliveira, additional, Pereira, Gabriel de Oliveira, additional, Fernandes, Fernanda Furtado, additional, Ferreira Neto, Pedro Paulo Martins, additional, Abdala, Guilherme Fontes de Sousa Skaf, additional, De Paula, Isadora Garcia, additional, Mendanha, Vinícius Coutinho, additional, Sintra, Heitor Carvalho, additional, Da Luz, Davi Mamede, additional, and Gonçalves, Eduarda Arantes, additional

Published
2023
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27. Perinatal asphyxia and hypothermic treatment from the endocrine perspective

Author

Improda, Nicola, primary, Capalbo, Donatella, additional, Poloniato, Antonella, additional, Garbetta, Gisella, additional, Dituri, Francesco, additional, Penta, Laura, additional, Aversa, Tommaso, additional, Sessa, Linda, additional, Vierucci, Francesco, additional, Cozzolino, Mariarosaria, additional, Vigone, Maria Cristina, additional, Tronconi, Giulia Maria, additional, del Pistoia, Marta, additional, Lucaccioni, Laura, additional, Tuli, Gerdi, additional, Munarin, Jessica, additional, Tessaris, Daniele, additional, de Sanctis, Luisa, additional, and Salerno, Mariacarolina, additional

Published
2023
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28. Indicações de cirurgia bariátrica e suas técnicas na atualidade: uma revisão integrativa à luz da literatura

Author

Ferreira, Gabriela Milhomem, primary, Poloniato, Luiz Felipe Castro Vaz, additional, Santana, Alexia Lorrainy Novato, additional, Coutinho, Nivea Maria de Carvalho, additional, Santos, Letícia Soares, additional, De Oliveira, Wanessa Guimarães, additional, Martins, Éryka Cristina Alves, additional, Valotto, Maria Tereza Tavares, additional, Arias, Valesca Naciff, additional, De Jesus, Daniela Souza, additional, Marçal, Geovanna Silva Nunes, additional, Fonseca, Flávia Medeiros, additional, and De Pinho, Lênio Airam, additional

Published
2023
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29. Indicações de toracotomia em centro cirúrgico no trauma: uma revisão à luz da literatura

Author

Ferreira, Gabriela Milhomem, primary, Poloniato, Luiz Felipe Castro Vaz, additional, Guerra, Luís Eduardo Cury, additional, Lima, Ana Vitória da Silva, additional, Garcia, Isabella Manfrim, additional, Dos Santos, Gabriella Nunes de Magalhães, additional, Da Silva, Gabriel Souza Santos, additional, Semkiw, Lucas Roberto Publitz, additional, Lopes, Pedro Augusto de Moraes, additional, Mendonça, Arthur Barbosa, additional, Da Silva, Isabella Heloiza Santana, additional, Brito, Isadora Pereira, additional, and Delevedove, Adriana Alves de Meneses, additional

Published
2023
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30. Diverticulite: manejo e técnicas cirúrgicas atualizadas

Author

Poloniato, Luiz Felipe Castro Vaz, primary, Mendes, Khauan Henrique da Silva, additional, Lacerda, Amanda Maria de Souza, additional, De Oliveira, Larissa Leite Vieira, additional, De Miranda Júnior, Petrônio Nilton, additional, Martins, Elianara Tavares, additional, Nascimento, Amanda Silva, additional, Braga, Bruna Letícia Martins, additional, Brito, Mariana Porto, additional, Piau, Arthur Vieira, additional, Monteiro, Larissa de Castro, additional, Kaluf, Larissa Madi, additional, and Azevedo, Andressa Araújo, additional

Published
2023
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31. ANÁLISE DA INSATISFAÇÃO COM A IMAGEM CORPORAL E DO COMPORTAMENTO ALIMENTAR ENTRE ESTUDANTES DE UMA ESCOLA MÉDICA EM GOIÁS

Author

Ferreira, Gabriela Milhomem, primary, Poloniato, Luiz Felipe Castro Vaz, additional, Oliveira, Gabriel Gonçalves Rezende, additional, Silva, Izabelle Martins, additional, Floresta, Laura Zabisky, additional, Dias, João Victor Almeida, additional, Lima, Ana Vitória da Silva, additional, Gouveia, Maria Thereza Yunes, additional, De Araújo, Isabella Correia Teodoro, additional, Guerra, Luís Eduardo Cury, additional, Guerra, Heloísa Silva, additional, Arantes, Cecília França, additional, Lopes, Pedro Augusto de Moraes, additional, Da Silva, Isabella Heloiza Santana, additional, and Guedes, Érika Paniago, additional

Published
2023
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32. PREVALÊNCIA E PERFIL DA UTILIZAÇÃO DE ESTERÓIDES ANABOLIZANTES ENTRE ESTUDANTES DE MEDICINA PRATICANTES DE TREINAMENTO DE FORÇA DE UMA ESCOLA MÉDICA

Author

Poloniato, Luiz Felipe Castro Vaz, primary, Ferreira, Gabriela Milhomem, additional, Oliveira, Gabriel Gonçalves Rezende, additional, Lima, Ana Vitória da Silva, additional, Silva, Izabelle Martins, additional, Gouveia, Maria Thereza Yunes, additional, De Alvarenga, Renan Ivo Horta, additional, Santos, Milena Lorraine Couto Franco, additional, Floresta, Isabela Zabisky, additional, Guerra, Heloísa Silva, additional, Semkiw, Lucas Roberto Publitz, additional, De Araújo, Isabella Correia Teodoro, additional, Arantes, Cecília França, additional, Mendonça, Arthur Barbosa, additional, and Guedes, Érika Paniago, additional

Published
2023
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34. Expanding the spectrum of neonatal‐onset AIFM1‐associated disorders

Author

Zambon, Alberto A., primary, Ghezzi, Daniele, additional, Baldoli, Cristina, additional, Cutillo, Gianni, additional, Fontana, Katia, additional, Sofia, Valentina, additional, Patricelli, Maria Grazia, additional, Nasca, Alessia, additional, Vinci, Stefano, additional, Spiga, Ivana, additional, Lamantea, Eleonora, additional, Fanelli, Giovanna F., additional, Sora, Maria Grazia Natali, additional, Rovelli, Rosanna, additional, Poloniato, Antonella, additional, Carrera, Paola, additional, Filippi, Massimo, additional, and Barera, Graziano, additional

Published
2023
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35. Analysis of HIV/Aids notifications in a municipality of national health between 2007 and 2017

Author

Rodrigo Alberton da Silva, Alexander Acauan de Aquino, Matheus Henrique Bernin Lima, Ana Victória Coletto Reichert, Augusto Poloniato Gelain, Julia Belato Teixeira, Luiz Casemiro Krzyzaniak Grando, Louise Pietrobon, and Deison Alencar Lucietto

Subjects
acquired immunodeficiency syndrome, HIV, disease notification, Medicine
Abstract

Introduction: Both human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) are part of the National List of Compulsory Notification of Diseases. Despite the compulsory reporting of HIV infection from 2014, there has been a drop in the detection of new cases in the last five years. Objective: Analyze the epidemiological data of HIV/AIDS case reports in the city of Passo Fundo, Rio Grande do Sul, from 2007 to 2017 in relation to gender, neighborhoods, notifying units and treatment units. Methods: Retrospective descriptive study, accomplished at the Health Surveillance Sector from the compulsory notifications available in the Information System of Notifiable Diseases (Sistema de Informação de Agravos de Notificação – SINAN). A spreadsheet was made in the Microsoft Excel® Program (2016). Data were analyzed using the SPSS® Program, descriptively through measures of prevalence, incidence and distribution. Results: There were 1,068 notifications. There was a predominance of males (55.5%) and in the age group from 27 to 43 years. Of the 31 notifying health units, three concentrated 95% of the cases: Specialized Care Service (74.7%); Hospital São Vicente de Paulo (16%); and Hospital das Clínicas of Passo Fundo (4%). The same three units concentrated 98.0% of the treatments: 88, 9 and 1%, respectively. The primary care accounted for 5.0% of the notifications. Conclusion: The higher prevalence in young adult men denotes the importance of prevention aimed at this audience. Notifications were mostly from hospitals and a public referral center, with little involvement of primary care in reporting HIV/AIDS.

Published
2019

36. Massive Amniotic Fluid Aspiration in a Case of Sudden Neonatal Death With Severe Hypoplasia of the Retrotrapezoid/Parafacial Respiratory Group

Author

Anna M. Lavezzi, Antonella Poloniato, Rosanna Rovelli, Laura Lorioli, Gabriela Alejandra Iasi, Teresa Pusiol, Graziano Barera, and Stefano Ferrero

Subjects
newborn, sudden neonatal death, amniotic fluid inhalation, brainstem, retrotrapezoid/parafacial respiratory group, hypoplasia, Pediatrics, RJ1-570
Abstract

We report a case of a baby, who, after pregnancy complicated by maternal Addison's disease and Hashimoto's thyroiditis and natural delivery, unexpectedly presented a cardiorespiratory collapse and died 1 hour after birth without responding to prolonged neonatal resuscitation maneuvers. The cause of death was reliably established by carrying out a forensic postmortem examination. More specifically, the histological examination of the lungs showed the presence of abundant endoalveolar and endobronchial cornea scales caused by absorption of amniotic fluid. The neuropathological examination of the brainstem highlighted severe hypodevelopment of the retrotrapezoid/parafacial respiratory group, which is a complex of neurons located in the caudal pons that is involved in respiratory rhythm coordination, especially expiration, in conditions of enhanced respiratory drive, as well as in chemoreception. This neuropathological finding shed new light on the mechanisms underlying the massive amniotic fluid aspiration which led to this early death.

Published
2019
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38. Mediação parental no uso do YouTube: Um estudo de caso no Brasil

Author

Amorim, Laura Palazi, Soares, Carolina Yuki Hara, Oliveira, Julia Poloniato Tesche, Deus, Diego Sebastião de, Nogueira, Adinan, Amorim, Laura Palazi, Soares, Carolina Yuki Hara, Oliveira, Julia Poloniato Tesche, Deus, Diego Sebastião de, and Nogueira, Adinan

Abstract

Este estudo de caso teve o objetivo de compreender de que maneira as famílias se portam mediante o consumo de conteúdo das (os) filhas (os) na plataforma YouTube. Trata-se de uma pesquisa descritiva quantitativa. A coleta de dados foi realizada por meio de um questionário on-line que foi aplicado a pais de alunos de colégios públicos e particulares da cidade de Poços de Caldas, em Minas de Gerais, no Brasil. Como referencial teórico, discutiu-se a presença da infância nos meios digitais na contemporaneidade, por meio do comportamento das crianças descritas com base nos direcionamentos de Tomé e Borges (2019), dada a relevância em desvendar de que modo os pais monitoram e medeiam este processo; assim como os estilos parentais de Baumrind (1991), no sentido de identificar qual tipo de comportamento dos responsáveis foi mais presente entre as respostas e resultados elucidados. Além disso, discutiu-se a necessidade do desenvolvimento de competências midiáticas por parte das crianças com base em Potter (2015). Partiu-se da hipótese de que haveria diferenças na mediação e estilos parentais a partir de questões socioeconômicas e de gênero. A análise estatística dos dados e das variáveis mostrou que a principal diferença na mediação está relacionada ao gênero: já que as mães possuem maior participação na mediação das crianças e se caracterizam por administrar uma responsabilidade simbólica acerca do comportamento delas na plataforma; enquanto os pais possuem uma responsabilidade material no sentido de fornecer às (aos) filhas (os) dispositivos tecnológicos digitais que lhes permitem acessar e navegar pela rede., This case study aimed to understand how parents act over the behavior of their children on the YouTube platform. This is a quantitative descriptive research. Data collection was carried out through a questionnaire that was applied to parents of students from public and private schools in the city of Poços de Caldas, located in Minas de Gerais, Brazil. As a theoretical reference, the presence of childhood in contemporary digital media was discussed based on the guidelines of Tomé and Borges (2019) given its relevance in unraveling how parents monitor and mediate this process; as well as the parenting styles of Baumrind (1991) in order to identify which type of behavior of those responsible was more present among the responses and results obtained and elucidated by this study. In addition, the need for children to develop media skills based on Potter (2015) was discussed. It was assumed that there would be differences in mediation and parenting styles based on socioeconomic issues. Statistical analysis of data and variables showed that there are small differences in mediation regarding gender: since mothers have greater participation in mediating children and are characterized by managing a symbolic responsibility for their behavior on the platform; while parents have a material responsibility in the sense of providing their daughters with digital technological devices that allow them to access and navigate the web.

Published
2023

39. High Risk of Secondary Infections Following Thrombotic Complications in Patients With COVID-19

Author

Ripa, Marco, Galli, Laura, D’Angelo, Armando, Apruzzi, Luca, Palumbo, Diego, Campochiaro, Corrado, Tassan Din, Chiara, Danise, Anna, Da Prat, Valentina, Vitali, Giordano, Brugliera, Luigia, Poli, Andrea, Monardo, Roberta, Monti, Giacomo, Baccellieri, Domenico, De Cobelli, Francesco, Clementi, Massimo, Iannaccone, Sandro, Dagna, Lorenzo, Rovere-Querini, Patrizia, Ciceri, Fabio, Tresoldi, Moreno, Zangrillo, Alberto, Scarpellini, Paolo, Castagna, Antonella, Andolina, Andrea, Bigoloni, Alba, Bossolasco, Simona, Bruzzesi, Elena, Canetti, Diana, Castiglioni, Barbara, Cernuschi, Massimo, Chiurlo, Matteo, Cinque, Paola, Dell’Acqua, Raffaele, Della Torre, Liviana, Gianotti, Nicola, Guffanti, Monica, Hasson, Hamid, Messina, Emanuela, Morsica, Giulia, Nozza, Silvia, Ranzenigo, Martina, Uberti-Foppa, Caterina, Vinci, Concetta, Badalucco Ciotta, Flavia, Bottanelli, Martina, Clemente, Tommaso, Mainardi, Ilaria, Mori, Giovanni, Papaioannu Borjesson, Rebecka, Ponta, Giacomo, Muccini, Camilla, Mastrangelo, Andrea, Oltolini, Chiara, Spagnuolo, Vincenzo, Benassi, Luca, Bigai, Giorgia, Bozzolo, Enrica, Borio, Giorgia, Bussolari, Cecilia, Calvisi, Stefania, Canti, Valentina, Castellani, Jacopo, Cavallo, Ludovica, Cilla, Marta, Cinel, Elena, Compagnone, Nicola, D’Aliberti, Teresa, Damanti, Sarah, De Lorenzo, Rebecca, Di Lucca, Giuseppe, Di Terlizzi, Gaetano, Dumea, Iulia, Farolfi, Federica, Ferrante, Marica, Frangi, Claudia, Gallina, Gabriele, Germinario Bruno, Nicolò, Lanzillotta, Marco, Li Voti, Raffaele, Marinosci, Alessandro, Martinenghi, Sabina, Memoli, Massimo, Montagna, Marco, Pascali, Maria, Patrizi, Alessandro, Pomaranzi, Chiara, Scotti, Raffaella, Strada, Silvia, Boffini, Nicola, Cavalli, Giulio, Della Torre, Emanuel, De Luca, Giacomo, Farina, Nicola, Moroni, Luca, Ramirez Giuseppe, Alvise, Tomelleri, Alessandro, Azzolini Maria, Luisa, Baiardo Redaelli, Martina, Calabrò Maria, Grazia, Casiraghi Giuseppina, Maria, Dell’Acqua, Antonio, Fresilli, Stefano, Guzzo, Francesca, Landoni, Giovanni, Lombardi, Gaetano, Maimeri, Nicolò, Moizo, Elena, Nisi Francesco, Giuseppe, Oriani, Alessandro, Ortalda, Alessandro, Pasculli, Nicola, Pieri, Marina, Turi, Stefano, Bertoglio, Luca, Bilman, Victor, Carletti, Silvia, Gona, Floriana, Mancini, Nicasio, Della Valle, Patrizia, Molinari, Chiara, Poloniato, Antonella, Lalla, Francesca, Prestifilippo, Dario, Sapienza, Jacopo, Seghi, Federico, Ripa, Marco, Galli, Laura, D’Angelo, Armando, Apruzzi, Luca, Palumbo, Diego, Campochiaro, Corrado, Tassan Din, Chiara, Danise, Anna, Da Prat, Valentina, Vitali, Giordano, Brugliera, Luigia, Poli, Andrea, Monardo, Roberta, Monti, Giacomo, Baccellieri, Domenico, De Cobelli, Francesco, Clementi, Massimo, Iannaccone, Sandro, Dagna, Lorenzo, Rovere-Querini, Patrizia, Ciceri, Fabio, Tresoldi, Moreno, Zangrillo, Alberto, Scarpellini, Paolo, Castagna, Antonella, Andolina, Andrea, Bigoloni, Alba, Bossolasco, Simona, Bruzzesi, Elena, Canetti, Diana, Castiglioni, Barbara, Cernuschi, Massimo, Chiurlo, Matteo, Cinque, Paola, Dell’Acqua, Raffaele, Della Torre, Liviana, Gianotti, Nicola, Guffanti, Monica, Hasson, Hamid, Messina, Emanuela, Morsica, Giulia, Nozza, Silvia, Ranzenigo, Martina, Uberti-Foppa, Caterina, Vinci, Concetta, Badalucco Ciotta, Flavia, Bottanelli, Martina, Clemente, Tommaso, Mainardi, Ilaria, Mori, Giovanni, Papaioannu Borjesson, Rebecka, Ponta, Giacomo, Muccini, Camilla, Mastrangelo, Andrea, Oltolini, Chiara, Spagnuolo, Vincenzo, Benassi, Luca, Bigai, Giorgia, Bozzolo, Enrica, Borio, Giorgia, Bussolari, Cecilia, Calvisi, Stefania, Canti, Valentina, Castellani, Jacopo, Cavallo, Ludovica, Cilla, Marta, Cinel, Elena, Compagnone, Nicola, D’Aliberti, Teresa, Damanti, Sarah, De Lorenzo, Rebecca, Di Lucca, Giuseppe, Di Terlizzi, Gaetano, Dumea, Iulia, Farolfi, Federica, Ferrante, Marica, Frangi, Claudia, Gallina, Gabriele, Germinario Bruno, Nicolò, Lanzillotta, Marco, Li Voti, Raffaele, Marinosci, Alessandro, Martinenghi, Sabina, Memoli, Massimo, Montagna, Marco, Pascali, Maria, Patrizi, Alessandro, Pomaranzi, Chiara, Scotti, Raffaella, Strada, Silvia, Boffini, Nicola, Cavalli, Giulio, Della Torre, Emanuel, De Luca, Giacomo, Farina, Nicola, Moroni, Luca, Ramirez Giuseppe, Alvise, Tomelleri, Alessandro, Azzolini Maria, Luisa, Baiardo Redaelli, Martina, Calabrò Maria, Grazia, Casiraghi Giuseppina, Maria, Dell’Acqua, Antonio, Fresilli, Stefano, Guzzo, Francesca, Landoni, Giovanni, Lombardi, Gaetano, Maimeri, Nicolò, Moizo, Elena, Nisi Francesco, Giuseppe, Oriani, Alessandro, Ortalda, Alessandro, Pasculli, Nicola, Pieri, Marina, Turi, Stefano, Bertoglio, Luca, Bilman, Victor, Carletti, Silvia, Gona, Floriana, Mancini, Nicasio, Della Valle, Patrizia, Molinari, Chiara, Poloniato, Antonella, Lalla, Francesca, Prestifilippo, Dario, Sapienza, Jacopo, and Seghi, Federico

Subjects
pulmonary embolism, Infectious Diseases, Oncology, bacteria, coronavirus, infections, thrombosis
Abstract

BackgroundThis study’s primary aim was to evaluate the impact of thrombotic complications on the development of secondary infections. The secondary aim was to compare the etiology of secondary infections in patients with and without thrombotic complications.MethodsThis was a cohort study (NCT04318366) of coronavirus disease 2019 (COVID-19) patients hospitalized at IRCCS San Raffaele Hospital between February 25 and June 30, 2020. Incidence rates (IRs) were calculated by univariable Poisson regression as the number of cases per 1000 person-days of follow-up (PDFU) with 95% confidence intervals. The cumulative incidence functions of secondary infections according to thrombotic complications were compared with Gray's method accounting for competing risk of death. A multivariable Fine-Gray model was applied to assess factors associated with risk of secondary infections.ResultsOverall, 109/904 patients had 176 secondary infections (IR, 10.0; 95% CI, 8.8–11.5; per 1000-PDFU). The IRs of secondary infections among patients with or without thrombotic complications were 15.0 (95% CI, 10.7–21.0) and 9.3 (95% CI, 7.9–11.0) per 1000-PDFU, respectively (P = .017). At multivariable analysis, thrombotic complications were associated with the development of secondary infections (subdistribution hazard ratio, 1.788; 95% CI, 1.018–3.140; P = .043). The etiology of secondary infections was similar in patients with and without thrombotic complications.ConclusionsIn patients with COVID-19, thrombotic complications were associated with a high risk of secondary infections.

Published
2022
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41. Untargeted and Targeted Metabolomic Profiling of Preterm Newborns with EarlyOnset Sepsis: A Case-Control Study

Author

Veronica Mardegan, Giuseppe Giordano, Matteo Stocchero, Paola Pirillo, Gabriele Poloniato, Enrica Donadel, Sabrina Salvadori, Carlo Giaquinto, Elena Priante, and Eugenio Baraldi

Subjects
sepsis, earlyonset sepsis, infant/newborn, metabolomics, biomarker, Microbiology, QR1-502
Abstract

Sepsis is a major concern in neonatology, but there are no reliable biomarkers for its early diagnosis. The aim of the study was to compare the metabolic profiles of plasma and urine samples collected at birth from preterm neonates with and without earlyonset sepsis (EOS) to identify metabolic perturbations that might orient the search for new early biomarkers. All preterm newborns admitted to the neonatal intensive care unit were eligible for this proof-of-concept, prospective case-control study. Infants were enrolled as “cases” if they developed EOS, and as “controls”if they did not. Plasma samples collected at birth and urine samples collected within 24 h of birth underwent untargeted and targeted metabolomic analysis using mass spectrometry coupled with ultra-performance liquid chromatography. Univariate and multivariate statistical analyses were applied. Of 123 eligible newborns, 15 developed EOS. These 15 newborns matched controls for gestational age and weight. Metabolomic analysis revealed evident clustering of the cases versus controls, with the glutathione and tryptophan metabolic pathways markedly disrupted in the former. In conclusion, neonates with EOS had a metabolic profile at birth that clearly distinguished them from those without sepsis, and metabolites of glutathione and tryptophan pathways are promising as new biomarkers of neonatal sepsis.

Published
2021
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42. Breathomics in Asthmatic Children Treated with Inhaled Corticosteroids

Author

Valentina Agnese Ferraro, Silvia Carraro, Paola Pirillo, Antonina Gucciardi, Gabriele Poloniato, Matteo Stocchero, Giuseppe Giordano, Stefania Zanconato, and Eugenio Baraldi

Subjects
pediatric asthma, breathomics, inhaled corticosteroids, endogenous steroid profile, Microbiology, QR1-502
Abstract

Background: “breathomics” enables indirect analysis of metabolic patterns underlying a respiratory disease. In this study, we analyze exhaled breath condensate (EBC) in asthmatic children before (T0) and after (T1) a three-week course of inhaled beclomethasone dipropionate (BDP). Methods: we recruited steroid-naive asthmatic children for whom inhaled steroids were indicated and healthy children, evaluating asthma control, spirometry and EBC (in asthmatics at T0 and T1). A liquid-chromatography–mass-spectrometry untargeted analysis was applied to EBC and a mass spectrometry-based target analysis to urine samples. Results: metabolomic analysis discriminated asthmatic (n = 26) from healthy children (n = 16) at T0 and T1, discovering 108 and 65 features relevant for the discrimination, respectively. Searching metabolomics databases, seven putative biomarkers with a plausible role in asthma biochemical–metabolic processes were found. After BDP treatment, asthmatic children, in the face of an improved asthma control (p < 0.001) and lung function (p = 0.01), showed neither changes in EBC metabolomic profile nor in urinary endogenous steroid profile. Conclusions: “breathomics” can discriminate asthmatic from healthy children, with prostaglandin, fatty acid and glycerophospholipid as putative markers. The three-week course of BDP—in spite of a significant clinical improvement—was not associated with changes in EBC metabolic arrangement and urinary steroid profile.

Published
2020
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43. Prenatal Management of Congenital Human Cytomegalovirus Infection in Seropositive Pregnant Patients Treated with Azathioprine

Author

Paolo Ivo Cavoretto, Chiara Fornara, Cristina Baldoli, Alessia Arossa, Milena Furione, Massimo Candiani, Patrizia Rovere Querini, Graziano Barera, Antonella Poloniato, Gerarda Gaeta, Arsenio Spinillo, and Daniele Lilleri

Subjects
congenital cytomegalovirus infection, azathioprine, pregnancy, ultrasound, fetal MRI, Medicine (General), R5-920
Abstract

Human cytomegalovirus (HCMV) is the leading infectious agent causing congenital disabilities. The risk of HCMV transmission to the fetus in pregnant women receiving immunosuppressive agents is unknown. We describe two cases of pregnant women with evidence of pre-conception HCMV protective immunity receiving azathioprine for ulcerative colitis or systemic lupus erythematosus. Both women reactivated the HCMV and transmitted the infection to the fetuses. One newborn showed unilateral hearing deficits and brain abnormalities while the other was asymptomatic. The mother of the symptomatic newborn had low levels of total and HCMV-specific blood CD4+ T cells. Women receiving immunosuppressive agents deserve information about the risk of HCMV congenital infection and should be monitored for HCMV infection during pregnancy. Their newborns should be screened for HCMV congenital infection.

Published
2020
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44. Parental mediation in the use of YouTube: A case study in Brazil

Author

Laura Palazi Amorim, Carolina Soares, Julia Poloniato Tesche Oliveira, Diego Sebastião de Deus, and Adinan Nogueira

Subjects
Nativos digitais, Mediação parental, Crianças, Youtube, General Medicine, Parental mediation, Children, Digital natives
Abstract

Este estudo de caso teve o objetivo de compreender de que maneira as famílias se portam mediante o consumo de conteúdo das (os) filhas (os) na plataforma YouTube. Trata-se de uma pesquisa descritiva quantitativa. A coleta de dados foi realizada por meio de um questionário on-line que foi aplicado a pais de alunos de colégios públicos e particulares da cidade de Poços de Caldas, em Minas de Gerais, no Brasil. Como referencial teórico, discutiu-se a presença da infância nos meios digitais na contemporaneidade, por meio do comportamento das crianças descritas com base nos direcionamentos de Tomé e Borges (2019), dada a relevância em desvendar de que modo os pais monitoram e medeiam este processo; assim como os estilos parentais de Baumrind (1991), no sentido de identificar qual tipo de comportamento dos responsáveis foi mais presente entre as respostas e resultados elucidados. Além disso, discutiu-se a necessidade do desenvolvimento de competências midiáticas por parte das crianças com base em Potter (2015). Partiu-se da hipótese de que haveria diferenças na mediação e estilos parentais a partir de questões socioeconômicas e de gênero. A análise estatística dos dados e das variáveis mostrou que a principal diferença na mediação está relacionada ao gênero: já que as mães possuem maior participação na mediação das crianças e se caracterizam por administrar uma responsabilidade simbólica acerca do comportamento delas na plataforma; enquanto os pais possuem uma responsabilidade material no sentido de fornecer às (aos) filhas (os) dispositivos tecnológicos digitais que lhes permitem acessar e navegar pela rede. This case study aimed to understand how parents act over the behavior of their children on the YouTube platform. This is a quantitative descriptive research. Data collection was carried out through a questionnaire that was applied to parents of students from public and private schools in the city of Poços de Caldas, located in Minas de Gerais, Brazil. As a theoretical reference, the presence of childhood in contemporary digital media was discussed based on the guidelines of Tomé and Borges (2019) given its relevance in unraveling how parents monitor and mediate this process; as well as the parenting styles of Baumrind (1991) in order to identify which type of behavior of those responsible was more present among the responses and results obtained and elucidated by this study. In addition, the need for children to develop media skills based on Potter (2015) was discussed. It was assumed that there would be differences in mediation and parenting styles based on socioeconomic issues. Statistical analysis of data and variables showed that there are small differences in mediation regarding gender: since mothers have greater participation in mediating children and are characterized by managing a symbolic responsibility for their behavior on the platform; while parents have a material responsibility in the sense of providing their daughters with digital technological devices that allow them to access and navigate the web.

Published
2023

46. Promoting the preservation of strawberry by supercritical CO2 drying

Author

Zambon, Alessandro, primary, Facco, Pierantonio, additional, Morbiato, Gianluca, additional, Toffoletto, Marta, additional, Poloniato, Gabriele, additional, Sut, Stefania, additional, Andrigo, Pietro, additional, Dall'Acqua, Stefano, additional, de Bernard, Marina, additional, and Spilimbergo, Sara, additional

Published
2022
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47. MALFORMAÇÃO ARTERIOVENOSA EM CARÓTIDA EXTERNA: UM RELATO DE CASO

Author

Cristina Zanatta Albarello, Eduardo Toaza, Augusto Poloniato Gelain, Thais Caroline Fin, Thiago de Bittencourt Buss, and Gabriela Cella

Subjects
General Medicine
Abstract

As malformações arteriovenosas (MAVs) são compostas por artérias e veias dilatadas diretamente ligadas por micro e macrofístulas hemodinamicamente ativas de alto fluxo e, diferentemente dos hemangiomas, não sofrem involução espontânea, sendo permanentes e caracterizadas por crescimento que acompanha o crescimento do indivíduo, podendo se agravar ao longo da vida do paciente por meio da dilatação progressiva dos vasos malformados. Clinicamente, se apresentam como uma nodulação revestida pela epiderme íntegra ou angiomatosa, com calor na região e podendo existir frêmito e sopro no local, sendo que com a progressão da MAV, as veias de drenagem distendem e podem se tornar evidentes. O artigo relata o caso de uma paciente feminina dde 38 anos com queixa de massa pulsátil crescente em região mentoniana direita da face. Ao exame físico, observava-se massa subcutânea em região mentoniana direita da face medindo cerca de 2,5cm de diâmetro, indolor à palpação, com frêmito ao toque e sopro à ausculta, sem alterações cutâneas ou sinais flogísticos.

Published
2021
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48. Maternal anxiety‐driven modulation of fetal limbic connectivity designs a backbone linking neonatal brain functional topology to socio‐emotional development in early childhood.

Author

Canini, Matteo, Pecco, Nicolò, Caglioni, Martina, Katušić, Ana, Išasegi, Iris Žunić, Oprandi, Claudia, Scifo, Paola, Pozzoni, Mirko, Lorioli, Laura, Garbetta, Gisella, Poloniato, Antonella, Sora, Maria Grazia Natali, Cavoretto, Paolo I., Barera, Graziano, Candiani, Massimo, Kostović, Ivica, Falini, Andrea, Baldoli, Cristina, and Della Rosa, Pasquale Anthony

Published
2023
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49. Temporal beta diversity patterns reveal global change impacts in closed mountain grasslands

Author

Chiara Lelli, Alessandro Chiarucci, Marcello Tomaselli, Michele Di Musciano, Cesare Lasen, Gianni Poloniato, Juri Nascimbene, Lelli C., Chiarucci A., Tomaselli M., Di Musciano M., Lasen C., Poloniato G., and Nascimbene J.

Subjects
climate change, snowbeds, Alpine grasslands, beta diversity, Dolomiti Bellunesi National Park, landuse change, resurvey, Alpine grassland, Plant Science, Ecology, Evolution, Behavior and Systematics
Abstract

Global changes are recognized as one of the main drivers of biodiversity changes over time, especially in mountain ecosystems. A key approach to detect and investigate the effect of climate and land use change on these ecosystems is represented by vegetation surveys. In this study, based on the resurvey of historical vegetation data, we assessed temporal beta-diversity patterns within and between subalpine and alpine vegetation types in the Dolomiti Bellunesi National Park. Resurvey was focussed on plots sampled in four main vegetation types: 1 and 2) Mesophytic and xerophytic grasslands on neutral or base-rich soils respectively dominated by Sesleria caerulea and Carex sempervirens and by Sesleria caerulea and Helictotrichon parlatorei; 3) Acidophytic grasslands dominated by Nardus stricta; 4) Snowbeds with dominance of dwarf willows (Salix herbacea or S. retusa) or Luzula alpinopilosa. Our results revealed a pattern of floristic homogenization in grasslands and snowbeds indicating a decreasing heterogeneity, both within and between different vegetation types that can be associated with different components of global change. The highest temporal beta diversity and floristic homogenization were detected in snowbeds. In general, the magnitude of temporal changes differ between communities, thus claiming for conservation activities that are tailored to each vegetation type.

Published
2022

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