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2. The impact of COVID-19 pandemic on surgical neuro-oncology: A survey from the Italian society of neurosurgery (SINch)

Author

Agosti, Edoardo, Aiello, Salvatore, Aiudi, Denis, Aleo, Danilo, Altieri, Roberto, Amoroso, Rosina, Auricchio, Anna Maria, Barbagallo, Giuseppe, Barbanera, Andrea, Beggio, Giacomo, Bianco, Andrea, Boccaletti, Riccardo, Borsa, Stefano, Canova, Giuseppe, Cappabianca, Paolo, Caroli, Manuela, Cavallo, Michele Alessandro, Certo, Francesco, Chimenti, Marcella, Chioffi, Franco, Cioffi, Valentina, Cofano, Fabio, Cossandi, Christian, D’Andrea, Giancarlo, De Falco, Raffaele, D'Elia, Alessandro, Della Pepa, Giuseppe Maria, Della Puppa, Alessandro, Della Torre, Attilio, Ferroli, Paolo, Garbossa, Diego, Germanò, Antonino, Giaquinta, Alessandra, Guida, Franco, Iacoangeli, Maurizio, Iacopino, Domenico Gerardo, Lavano, Angelo, Maimone, Giuseppe, Maiola, Vincenza, Mauferi, Rosario, Melatini, Alessandro, Moro, Mario, Murrone, Domenico, Muscas, Giovanni, Oppido, Piero Andrea, Pignotti, Fabrizio, Policicchio, Domenico, Proto, Piermassimo, Quaglietta, Paolo, Raco, Antonino, Renisi, Giulia, Ricciardi, Luca, Romeo, Francesco, Rossetto, Marta, Scerrati, Alba, Schwarz, Andreas, Skrap, Miran, Somma, Carlo, Somma, Teresa, Spena, Giannantonio, Telera, Stefano, Tosatto, Luigino, Tropeano, Maria Pia, Volpin, Francesco, Volpin, Lorenzo, Zoia, Cesare, Zanin, Luca, Ius, Tamara, Panciani, Pier Paolo, Esposito, Felice, Gori, Andrea, Fontanella, Marco Maria, Angileri, Filippo Flavio, Sabatino, Giovanni, Olivi, Alessandro, Esposito, Vincenzo, and Pessina, Federico

Published
2023
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3. 3D Skull Prosthesis

Author

Boccaletti, Riccardo, Policicchio, Domenico, Zoccali, Carmine, editor, Ruggieri, Pietro, editor, and Benazzo, Francesco, editor

Published
2022
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11. The impact of COVID-19 pandemic on surgical neuro-oncology: A survey from the Italian society of neurosurgery (SINch)

Author

Zanin, Luca, primary, Ius, Tamara, additional, Panciani, Pier Paolo, additional, Esposito, Felice, additional, Gori, Andrea, additional, Fontanella, Marco Maria, additional, Tropeano, Maria Pia, additional, Raco, Antonino, additional, Angileri, Filippo Flavio, additional, Sabatino, Giovanni, additional, Olivi, Alessandro, additional, Esposito, Vincenzo, additional, Pessina, Federico, additional, Agosti, Edoardo, additional, Aiello, Salvatore, additional, Aiudi, Denis, additional, Aleo, Danilo, additional, Altieri, Roberto, additional, Amoroso, Rosina, additional, Auricchio, Anna Maria, additional, Barbagallo, Giuseppe, additional, Barbanera, Andrea, additional, Beggio, Giacomo, additional, Bianco, Andrea, additional, Boccaletti, Riccardo, additional, Borsa, Stefano, additional, Canova, Giuseppe, additional, Cappabianca, Paolo, additional, Caroli, Manuela, additional, Cavallo, Michele Alessandro, additional, Certo, Francesco, additional, Chimenti, Marcella, additional, Chioffi, Franco, additional, Cioffi, Valentina, additional, Cofano, Fabio, additional, Cossandi, Christian, additional, D’Andrea, Giancarlo, additional, De Falco, Raffaele, additional, D'Elia, Alessandro, additional, Della Pepa, Giuseppe Maria, additional, Della Puppa, Alessandro, additional, Della Torre, Attilio, additional, Ferroli, Paolo, additional, Garbossa, Diego, additional, Germanò, Antonino, additional, Giaquinta, Alessandra, additional, Guida, Franco, additional, Iacoangeli, Maurizio, additional, Iacopino, Domenico Gerardo, additional, Lavano, Angelo, additional, Maimone, Giuseppe, additional, Maiola, Vincenza, additional, Mauferi, Rosario, additional, Melatini, Alessandro, additional, Moro, Mario, additional, Murrone, Domenico, additional, Muscas, Giovanni, additional, Oppido, Piero Andrea, additional, Pignotti, Fabrizio, additional, Policicchio, Domenico, additional, Proto, Piermassimo, additional, Quaglietta, Paolo, additional, Renisi, Giulia, additional, Ricciardi, Luca, additional, Romeo, Francesco, additional, Rossetto, Marta, additional, Scerrati, Alba, additional, Schwarz, Andreas, additional, Skrap, Miran, additional, Somma, Carlo, additional, Somma, Teresa, additional, Spena, Giannantonio, additional, Telera, Stefano, additional, Tosatto, Luigino, additional, Volpin, Francesco, additional, Volpin, Lorenzo, additional, and Zoia, Cesare, additional

Published
2023
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24. Multimodal Surgical Management of Cerebral Lesions in Motor-Eloquent Areas Combining Intraoperative 3D Ultrasound with Neurophysiological Mapping.

Author

Policicchio, Domenico, Ticca, Stefano, Dipellegrini, Giosuè, Doda, Artan, Muggianu, Giampiero, and Boccaletti, Riccardo

Subjects
*ULTRASONIC imaging, *INTRAOPERATIVE monitoring, *EFFERENT pathways, *ARTERIOVENOUS malformation, *BRAIN damage, TUMOR surgery
Abstract

Background Resection of tumors adjacent to motor pathways carries risks of both postoperative motor deficit and incomplete resection. Our aim was to assess usefulness and limitations of a multimodal strategy that combines intraoperative ultrasound (iUS) guided resection with intraoperative neurophysiology. Methodology This is a prospective study of 25 patients with brain lesions adjacent to motor areas who underwent intracranial surgery with assistance of the iUS guidance system and intraoperative neurophysiological monitoring and mapping. Pathologies treated included 19 gliomas, 3 metastases, 1 anaplastic meningioma, 1 arteriovenous malformation (AVM), and 1 ependymoma. The iUS-guided lesion removal accuracy and the extent of resection were estimated and compared with a 30-day postoperative brain MRI. The results were assessed considering the extent of resection related to 6-month motor function outcome. Results iUS was accurate in checking the extent of resection in 17 patients, whereas in 8 cases the decline of the iUS images quality did not allow a valuable assessment. Positive mapping was obtained in 16 patients. Gross total resection was achieved in 16 patients. In five of nine cases with subtotal resection, surgery was stopped because a functional area was reached. In four patients, tumor removal was limited due to the difficulty of identifying neoplastic tissue. Motor function worsening was transient in six patients and permanent in two. Conclusions The integrated use of intraoperative neuromonitoring to identify motor areas and iUS to identify tumor–tissue interface could help increase the rate of radical resection respecting the eloquent areas. [ABSTRACT FROM AUTHOR]

Published
2021
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26. Ventriculitis due to Staphylococcus lugdunensis: two case reports

Author

Spanu Teresa, Rigante Donato, Tamburrini Gianpiero, Fiori Barbara, D'Inzeo Tiziana, Posteraro Brunella, Policicchio Domenico, Sanguinetti Maurizio, and Fadda Giovanni

Subjects
Medicine
Abstract

Abstract Introduction Staphylococcus lugdunensis is an unusually virulent coagulase-negative staphylococcus that has rarely been implicated in central nervous system infections. Case presentation Two children hospitalized in the Neurosurgery Unit developed ventriculitis caused by methicillin-resistant Staphylococcus lugdunensis following placement of external ventriculostomy drains. The causative organisms were identified by molecular studies. The patients recovered without significant sequelae after high doses of intrathecal vancomycin. Conclusion Distinguishing Staphylococcus lugdunensis from other coagulase-negative staphylococcus species is crucial because it carries a substantial risk for severe central nervous system infections displayed by patients with implanted cerebrospinal fluid devices. Clinicians should not underestimate the importance of the isolation of this species from cerebrospinal fluid specimens.

Published
2008
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27. Letter to the editor regarding the article 'traumatic iatrogenic dissecting anterior cerebral artery aneurysms: conservative management as a therapeutic option'.

Author

Policicchio, Domenico, Boccaletti, Riccardo, and Aiello, Giovanni

Subjects
*ANTERIOR cerebral artery, *INTRACRANIAL aneurysms, *DISSECTING aneurysms, *DIGITAL subtraction angiography, *IATROGENIC diseases, *CEREBRAL angiography
Abstract

This document is a letter to the editor of the British Journal of Neurosurgery regarding an article titled "Traumatic iatrogenic dissecting anterior cerebral artery aneurysms: conservative management as a therapeutic option." The authors of the letter express their interest in the article and discuss two points of concern. Firstly, they question the use of different images in the illustrations, suggesting that using the same projection and magnification would have made it easier for readers to interpret and compare the angiographies. Secondly, they express their disagreement with the choice of conservative therapy for traumatic intracranial aneurysms, citing the high risk of bleeding and the need for prompt treatment according to most literature. They suggest conducting a systematic review of the literature before considering conservative management as a safe option. [Extracted from the article]

Published
2023
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31. Callosotomy

Author

Colicchio, Gabriella and Policicchio, Domenico

Subjects
Epilepsy, Settore MED/27 - NEUROCHIRURGIA
Published
2011

32. Unilateral extradural motor cortex stimulation is safe and improves Parkinson disease at 1 year

Author

Bentivoglio, Ar, Fasano, Alfonso, Piano, Carla, Soleti, Francesco, Daniele, Antonio, Zinno, Massimiliano, Piccininni, Chiara, De Simone, Celestino, Policicchio, Domenico, Tufo, Tommaso, Meglio, Mario, Cioni, Beatrice, Daniele, Antonio (ORCID:0000-0003-1641-5852), Cioni, Beatrice (ORCID:0000-0002-6830-6204), Bentivoglio, Ar, Fasano, Alfonso, Piano, Carla, Soleti, Francesco, Daniele, Antonio, Zinno, Massimiliano, Piccininni, Chiara, De Simone, Celestino, Policicchio, Domenico, Tufo, Tommaso, Meglio, Mario, Cioni, Beatrice, Daniele, Antonio (ORCID:0000-0003-1641-5852), and Cioni, Beatrice (ORCID:0000-0002-6830-6204)

Abstract

The primary motor cortex, which is part of the corticobasal ganglia loops, may be an alternative option for the surgical treatment of Parkinson disease.

Published
2012

33. Unilateral Extradural Motor Cortex Stimulation is Safe and Improves Parkinson's Disease at 1 Year

Author

Bentivoglio, Anna Rita, Fasano, Alfonso, Piano, Carla, Soleti, Francesco, Daniele, Antonio, Zinno, Massimiliano, Piccininni, Chiara, De Simone, Clara, Policicchio, Domenico, Tufo, Tommaso, Meglio, Mario, Cioni, Beatrice, Bentivoglio, Anna Rita (ORCID:0000-0002-9663-095X), Daniele, Antonio (ORCID:0000-0003-1641-5852), De Simone, Clara (ORCID:0000-0002-0898-0045), Cioni, Beatrice (ORCID:0000-0002-6830-6204), Bentivoglio, Anna Rita, Fasano, Alfonso, Piano, Carla, Soleti, Francesco, Daniele, Antonio, Zinno, Massimiliano, Piccininni, Chiara, De Simone, Clara, Policicchio, Domenico, Tufo, Tommaso, Meglio, Mario, Cioni, Beatrice, Bentivoglio, Anna Rita (ORCID:0000-0002-9663-095X), Daniele, Antonio (ORCID:0000-0003-1641-5852), De Simone, Clara (ORCID:0000-0002-0898-0045), and Cioni, Beatrice (ORCID:0000-0002-6830-6204)

Abstract

BACKGROUND:: The primary motor cortex, which is part of the cortical-basal ganglia loops, may be an alternative option for the surgical treatment of Parkinson's disease. OBJECTIVE:: To report on the 1-year safety and efficacy of unilateral extradural motor cortex stimulation in Parkinson's disease. METHODS:: A quadripolar electrode strip was extradurally implanted over the motor cortex. Stimulation was continuously delivered through the electrode paddle contralateral to the most affected clinical side. Subjects were prospectively evaluated by the Unified Parkinson's Disease Rating Scale (UPDRS) and the Parkinson's disease quality of life questionnaire. In addition, an extensive cognitive and behavioral assessment and EEG recording was performed. RESULTS:: Nine patients were included in this study. No surgical complications or adverse events occurred. Moreover, no cognitive or behavioral changes were observed.Under the OFF-medication condition, the UPDRS III at baseline was reduced by 14.1%, 23.3%, 19.9%, and 13.2%, at 1, 3, 6, and 12 months, respectively. The motor effects were bilateral, appeared after 3-4weeks of stimulation, and outlasted the stimulation itself for 3-4 weeks in one case of stimulator accidental switching off. The UPDRS IV was reduced by 40.8%, 42.1% and 35.5% at 1, 3 and 12 months, respectively. The Parkinson's disease quality of life questionnaire was increased at months 3, 6, and 12. CONCLUSION:: Extradural motor cortex stimulation is a safe procedure. After 12 months, the patients demonstrated a moderate improvement of motor symptoms (particularly, in axial symptoms) and quality of life.

Published
2012

34. Callosotomy

Author

Lavano A, Lanotte M, Landi A, Colicchio, Gabriella, Policicchio, Domenico, Lavano A, Lanotte M, Landi A, Colicchio, Gabriella, and Policicchio, Domenico

Abstract

Corpus callosotomy is a reasonably safe and effective palliative surgical procedure for some patients with intractable seizures who are not amenable to focal resection, it does not pretend to suppress seizures, but it aims at alleviating them, by reducing their severity [13, 14, 15]. This is a feasible and costeffective treatment for some patients, even those in developing countries and with limited resources [19]. It is useful for seizure control in adult and in children, particularly in children with catastrophic epilepsy syndromes. Lennox-Gastaut syndrome is the most common one and the result of seizure control is significant. Severe mental retardation is not a contraindication to perform callosotomy. As a reguard seizure type generalized seizures with fall (Drop-Attack) are the most responsive to callosotomy. Seizure control , when obtained, is stable over time [13]. Improved seizure control after callostomy is always associated with improved QOL, satisfaction of parents to the operation, and also satisfaction of family QOL. Significant neuropsychological deficits are evident only on formal testing, are usually ignored by patients/family members, and rarely cause impact on daily life.

Published
2011

35. Ventriculitis due to Staphylococcus lugdunensis: two case reports

Author

Spanu, Teresa, Rigante, Donato, Tamburrini, Gianpiero, Fiori, Barbara, D'Inzeo, Tiziana, Posteraro, Brunella, Policicchio, Domenico, Sanguinetti, Maurizio, Fadda, Giovanni, Spanu, Teresa (ORCID:0000-0003-1864-5184), Rigante, Donato (ORCID:0000-0001-7032-7779), Tamburrini, Gianpiero (ORCID:0000-0002-7139-5711), Fiori, Barbara (ORCID:0000-0003-3318-5809), D'Inzeo, Tiziana (ORCID:0000-0003-1508-3518), Posteraro, Brunella (ORCID:0000-0002-1663-7546), Sanguinetti, Maurizio (ORCID:0000-0002-9780-7059), Spanu, Teresa, Rigante, Donato, Tamburrini, Gianpiero, Fiori, Barbara, D'Inzeo, Tiziana, Posteraro, Brunella, Policicchio, Domenico, Sanguinetti, Maurizio, Fadda, Giovanni, Spanu, Teresa (ORCID:0000-0003-1864-5184), Rigante, Donato (ORCID:0000-0001-7032-7779), Tamburrini, Gianpiero (ORCID:0000-0002-7139-5711), Fiori, Barbara (ORCID:0000-0003-3318-5809), D'Inzeo, Tiziana (ORCID:0000-0003-1508-3518), Posteraro, Brunella (ORCID:0000-0002-1663-7546), and Sanguinetti, Maurizio (ORCID:0000-0002-9780-7059)

Abstract

Staphylococcus lugdunensis is an unusually virulent coagulase-negative staphylococcus that has rarely been implicated in central nervous system infections.

Published
2008

36. Effect of vagal nerve stimulation on systemic inflammation and cardiac autonomic function in patients with refractory epilepsy

Author

Barone, Lucy, Colicchio, Gabriella, Policicchio, Domenico, Di Clemente, Francesca, Di Monaco, Antonio, Meglio, Mario, Lanza, Gaetano Antonio, Crea, Filippo, Lanza, Gaetano Antonio (ORCID:0000-0003-2187-6653), Crea, Filippo (ORCID:0000-0001-9404-8846), Barone, Lucy, Colicchio, Gabriella, Policicchio, Domenico, Di Clemente, Francesca, Di Monaco, Antonio, Meglio, Mario, Lanza, Gaetano Antonio, Crea, Filippo, Lanza, Gaetano Antonio (ORCID:0000-0003-2187-6653), and Crea, Filippo (ORCID:0000-0001-9404-8846)

Abstract

Recent data suggest that vagus nerve stimulation (VNS) can inhibit cytokine release by inflammatory cells. Accordingly, an association between impaired cardiac parasympathetic function, as assessed by heart rate variability (HRV), and increased markers of inflammation has recently been reported. In this study we assessed the effect of direct left VNS on inflammatory markers and HRV in patients with refractory epilepsy.

Published
2007

37. Transcranial cerebral herniation after chronic subdural hematoma treatment with no dura closure

Author

Doglietto, Francesco, Sabatino, Giovanni, Policicchio, Domenico, Tirpakova, Barbora, Albanese, Alessio, Doglietto F. (ORCID:0000-0002-7438-0734), Sabatino G. (ORCID:0000-0002-4227-0434), Policicchio D., Tirpakova B., Albanese A. (ORCID:0000-0001-8783-2974), Doglietto, Francesco, Sabatino, Giovanni, Policicchio, Domenico, Tirpakova, Barbora, Albanese, Alessio, Doglietto F. (ORCID:0000-0002-7438-0734), Sabatino G. (ORCID:0000-0002-4227-0434), Policicchio D., Tirpakova B., and Albanese A. (ORCID:0000-0001-8783-2974)

Abstract

Subdural hematoma

Published
2006

38. Seizure suppression after left anterior temporal lobectomy in a patient with an ipsilateral parietal lesion

Author

Barba, C, Policicchio, Domenico, Doglietto, Francesco, Papacci, Fabio, Colicchio, Gabriella, Doglietto, Francesco (ORCID:0000-0002-7438-0734), Papacci, Fabio (ORCID:0000-0001-8742-2713), Barba, C, Policicchio, Domenico, Doglietto, Francesco, Papacci, Fabio, Colicchio, Gabriella, Doglietto, Francesco (ORCID:0000-0002-7438-0734), and Papacci, Fabio (ORCID:0000-0001-8742-2713)

Abstract

Epilepsy surgery can provide a solution for drug-resistant patients (Revlyn, 2003). Non-lesional epilepsies account for 20–30% of patients in major epilepsy surgery centres (Cascino, 2001).

Published
2005

39. Unusual ipsilateral hyperkinetic automatisms in SMA seizures.

Author

Colicchio, Gabriella, Doglietto, Francesco, Policicchio, Domenico, Barba, Carmen, Caulo, Massimo, Doglietto, Francesco (ORCID:0000-0002-7438-0734), Colicchio, Gabriella, Doglietto, Francesco, Policicchio, Domenico, Barba, Carmen, Caulo, Massimo, and Doglietto, Francesco (ORCID:0000-0002-7438-0734)

Abstract

PURPOSE: To describe repetitive movements of the right arm possibly originating from the ipsilateral SMA area in two drug-resistant epileptic patients. METHODS: Two epileptic patients (one female, one male, 35 and 36 years old, respectively) were submitted to pre-surgical evaluation including history, neurological examination, long-term video-EEG monitoring, interictal and ictal SPET, MRI and fMRI, neuropsychological assessment. Invasive recordings (stereoelectroencephalography) were also performed. RESULTS: In both patients ictal semiology was characterized by very stereotyped repetitive right arm movements, i.e. tapping towards the thorax (movement rate of 6-7 Hz and 3-4 Hz for the two subjects, respectively). Seizures in the first patient, whose epilepsy was cryptogenetic, originated from the right pre-SMA area, which was surgically removed. She is seizure free 2 years after the operation. In the second patient, in whom a right pre-frontal post-abscess porencephaly was disclosed, the epileptogenic zone included the lesion and surrounding areas, while the SMA area was involved less consistently. CONCLUSIONS: Even if, according to literature, SMA epilepsy is predominantly characterized by postural manifestations, ipsilateral repetitive movements could be a relevant sign in this kind of epilepsy, as showed in our first patient. The presence of similar semiology in the second patient, might suggest that the symptomatogenic zone involved SMA area.

Published
2005

40. Unilateral Extradural Motor Cortex Stimulation Is Safe and Improves Parkinson Disease at 1 Year

Author

Bentivoglio, Anna Rita, primary, Fasano, Alfonso, additional, Piano, Carla, additional, Soleti, Francesco, additional, Daniele, Antonio, additional, Zinno, Massimiliano, additional, Piccininni, Chiara, additional, De Simone, Celestino, additional, Policicchio, Domenico, additional, Tufo, Tommaso, additional, Meglio, Mario, additional, and Cioni, Beatrice, additional

Published
2012
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43. Evaluation of the clinical efficacy of idebenone in patients affected by chronic cerebrovascular disorders

Author

Lingetti, Mario, primary, Porfido, Francesco Antonio, additional, Ciarimboli, Mario, additional, Oliviero, Ugo, additional, Cocozza, Manlio, additional, Coto, Vincenzo, additional, Policicchio, Domenico, additional, Carifi, Saverio, additional, Piermatteo, Efrem, additional, Lombardi, Rosanna, additional, Tranfaglia, Emilio, additional, and Di Grazia, Francesco, additional

Published
1992
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44. Effect of Vagal Nerve Stimulation on Systemic Inflammation and Cardiac Autonomic Function in Patients with Refractory Epilepsy.

Author

Barone, Lucy, Colicchio, Gabriella, Policicchio, Domenico, Di Clemente, Francesca, Di Monaco, Antonio, Meglio, Mario, Lanza, Gaetano A., and Crea, Filippo

Abstract

Objective: Recent data suggest that vagus nerve stimulation (VNS) can inhibit cytokine release by inflammatory cells. Accordingly, an association between impaired cardiac parasympathetic function, as assessed by heart rate variability (HRV), and increased markers of inflammation has recently been reported. In this study we assessed the effect of direct left VNS on inflammatory markers and HRV in patients with refractory epilepsy. Methods: A 24-hour electrocardiogram Holter recording was performed both at baseline and after 3 months of left VNS in 8 patients (age 32 ± 24 years, 2 men) who underwent implantation of a VNS device because of refractory epilepsy. Tumor necrosis factor-α, interleukin-6 and C-reactive protein serum levels were measured, as markers of inflammation, at the same times. Results: No significant changes were found after 3 months of left VNS, compared to baseline, both for HRV variables and inflammatory markers. Also, no consistent correlation could be demonstrated between HRV parameters and inflammatory markers in these patients. Conclusions: Our data in epileptic patients without cardiovascular disease failed to show a significant effect of left VNS on cardiac autonomic function and on systemic inflammation at short-term follow-up. Copyright © 2008 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

Published
2008
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