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662 results on '"Poletti, Barbara"'

3. Prevalence and motor-functional correlates of frontotemporal-spectrum disorders in a large cohort of non-demented ALS patients

Author

Poletti, Barbara, Aiello, Edoardo Nicolò, Consonni, Monica, Iazzolino, Barbara, Torre, Silvia, Solca, Federica, Faltracco, Veronica, Telesca, Alessandra, Palumbo, Francesca, Dalla Bella, Eleonora, Bersano, Enrica, Riva, Nilo, Verde, Federico, Messina, Stefano, Doretti, Alberto, Maranzano, Alessio, Morelli, Claudia, Calvo, Andrea, Silani, Vincenzo, Lauria, Giuseppe, Chiò, Adriano, and Ticozzi, Nicola

Published
2024
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6. How to detect affect recognition alterations in amyotrophic lateral sclerosis

Author

Castelnovo, Veronica, Canu, Elisa, Aiello, Edoardo Nicolò, Curti, Beatrice, Sibilla, Elisa, Torre, Silvia, Freri, Fabiola, Tripodi, Chiara, Lumaca, Laura, Spinelli, Edoardo Gioele, Schito, Paride, Russo, Tommaso, Falzone, Yuri, Verde, Federico, Silani, Vincenzo, Ticozzi, Nicola, Sturm, Virginia E., Rankin, Katherine P., Gorno-Tempini, Maria Luisa, Poletti, Barbara, Filippi, Massimo, and Agosta, Federica

Published
2024
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7. Does botulinum toxin affect psycho-social aspects in dystonia?

Author

Marfoli, Angelica, Mameli, Francesca, Aiello, Edoardo Nicolò, Ruggiero, Fabiana, Sandi, Angelica De, Mellace, Denise, Curti, Beatrice, Vimercati, Roberto, Poletti, Barbara, Ticozzi, Nicola, Chieffo, Daniela, Santangelo, Gabriella, Barbieri, Sergio, Priori, Alberto, and Ferrucci, Roberta

Published
2024
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10. Correction: Clinimetrics and feasibility of the Italian version of the Frontal Assessment Battery (FAB) in non-demented Parkinson’s disease patients

Author

Aiello, Edoardo Nicolò, D’Iorio, Alfonsina, Solca, Federica, Torre, Silvia, Bonetti, Ruggero, Scheveger, Francesco, Colombo, Eleonora, Maranzano, Alessio, Maderna, Luca, Morelli, Claudia, Doretti, Alberto, Amboni, Marianna, Vitale, Carmine, Verde, Federico, Ferrucci, Roberta, Barbieri, Sergio, Zirone, Eleonora, Priori, Alberto, Pravettoni, Gabriella, Santangelo, Gabriella, Silani, Vincenzo, Ticozzi, Nicola, Ciammola, Andrea, and Poletti, Barbara

Published
2024
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13. Reliable change indices for the Italian version of the Montreal Cognitive Assessment (MoCA) in non-demented Parkinson’s disease patients

Author

Aiello, Edoardo Nicolò, Solca, Federica, Torre, Silvia, Curti, Beatrice, De Luca, Giulia, Bonetti, Ruggero, Scheveger, Francesco, Colombo, Eleonora, Maranzano, Alessio, Olivero, Marco, Morelli, Claudia, Doretti, Alberto, Maderna, Luca, Verde, Federico, Ferrucci, Roberta, Barbieri, Sergio, Ruggiero, Fabiana, Mellace, Denise, Marfoli, Angelica, De Sandi, Angelica, Priori, Alberto, Pravettoni, Gabriella, Silani, Vincenzo, Ticozzi, Nicola, Ciammola, Andrea, and Poletti, Barbara

Published
2024
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14. Clinical validity of the Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB) in Mild Cognitive Impairment and Alzheimer’s Disease

Author

Conca, Francesca, Esposito, Valentina, Catricalà, Eleonora, Manenti, Rosa, L’Abbate, Federica, Quaranta, Davide, Giuffrè, Guido Maria, Rossetto, Federica, Solca, Federica, Orso, Beatrice, Inguscio, Emanuela, Crepaldi, Valeria, De Matteis, Maddalena, Rotondo, Emanuela, Manera, Marina, Caruso, Giulia, Catania, Valentina, Canu, Elisa, Rundo, Francesco, Cotta Ramusino, Matteo, Filippi, Massimo, Fundarò, Cira, Piras, Federica, Arighi, Andrea, Tiraboschi, Pietro, Stanzani Maserati, Michelangelo, Pardini, Matteo, Poletti, Barbara, Silani, Vincenzo, Marra, Camillo, Di Tella, Sonia, Cotelli, Maria, Lodi, Raffaele, Tagliavini, Fabrizio, and Cappa, Stefano Francesco

Published
2024
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15. Validity, diagnostics and feasibility of the Italian version of the Montreal Cognitive Assessment (MoCA) in Huntington’s disease

Author

Aiello, Edoardo Nicolò, Solca, Federica, Torre, Silvia, Lafronza, Annalisa, Maranzano, Alessio, Bonetti, Ruggero, Scheveger, Francesco, Maffi, Sabrina, Ceccarelli, Consuelo, Scocchia, Marta, Casella, Melissa, Verde, Federico, Migliore, Simone, Silani, Vincenzo, Ticozzi, Nicola, Squitieri, Ferdinando, Ciammola, Andrea, and Poletti, Barbara

Published
2024
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25. Correction: Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I‑UDSNB 1.0): development and normative data

Author

Conca, Francesca, Esposito, Valentina, Rundo, Francesco, Quaranta, Davide, Muscio, Cristina, Manenti, Rosa, Caruso, Giulia, Lucca, Ugo, Galbussera, Alessia Antonella, Di Tella, Sonia, Baglio, Francesca, L’Abbate, Federica, Canu, Elisa, Catania, Valentina, Filippi, Massimo, Mattavelli, Giulia, Poletti, Barbara, Silani, Vincenzo, Lodi, Raffaele, De Matteis, Maddalena, Maserati, Michelangelo Stanzani, Arighi, Andrea, Rotondo, Emanuela, Tanzilli, Antonio, Pace, Andrea, Garramone, Federica, Cavaliere, Carlo, Pardini, Matteo, Rizzetto, Cristiano, Sorbi, Sandro, Perri, Roberta, Tiraboschi, Pietro, Canessa, Nicola, Cotelli, Maria, Ferri, Raffaele, Weintraub, Sandra, Marra, Camillo, Tagliavini, Fabrizio, Catricalà, Eleonora, and Cappa, Stefano Francesco

Published
2023
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26. Equating norms between the ALS Cognitive Behavioral Screen (ALS-CBS™) and the Edinburgh Cognitive and Behavioural ALS Screen (ECAS) in non-demented ALS patients

Author

Aiello, Edoardo Nicolò, Solca, Federica, Greco, Lucia Catherine, Torre, Silvia, Carelli, Laura, Morelli, Claudia, Doretti, Alberto, Colombo, Eleonora, Messina, Stefano, Pain, Debora, Radici, Alice, Lizio, Andrea, Casiraghi, Jacopo, Cerri, Federica, Woolley, Susan, Murphy, Jennifer, Tremolizzo, Lucio, Appollonio, Ildebrando, Verde, Federico, Sansone, Valeria Ada, Lunetta, Christian, Silani, Vincenzo, Ticozzi, Nicola, and Poletti, Barbara

Published
2023
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28. Clinimetrics and feasibility of the Italian version of the Frontal Assessment Battery (FAB) in non-demented Parkinson’s disease patients

Author

Aiello, Edoardo Nicolò, D’Iorio, Alfonsina, Solca, Federica, Torre, Silvia, Bonetti, Ruggero, Scheveger, Francesco, Colombo, Eleonora, Maranzano, Alessio, Maderna, Luca, Morelli, Claudia, Doretti, Alberto, Amboni, Marianna, Vitale, Carmine, Verde, Federico, Ferrucci, Roberta, Barbieri, Sergio, Zirone, Eleonora, Priori, Alberto, Pravettoni, Gabriella, Santangelo, Gabriella, Silani, Vincenzo, Ticozzi, Nicola, Ciammola, Andrea, and Poletti, Barbara

Published
2023
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32. Clinimetrics of the cognitive section of the Italian ALS Cognitive Behavioral Screen (ALS-CBS™)

Author

Aiello, Edoardo Nicolò, Greco, Lucia Catherine, La Tona, Antonino, Solca, Federica, Torre, Silvia, Carelli, Laura, Pain, Debora, Radici, Alice, Lizio, Andrea, Casiraghi, Jacopo, Cerri, Federica, Brugnera, Agostino, Compare, Angelo, Woolley, Susan, Murphy, Jennifer, Tremolizzo, Lucio, Appollonio, Ildebrando, Verde, Federico, Silani, Vincenzo, Ticozzi, Nicola, Lunetta, Christian, Sansone, Valeria Ada, and Poletti, Barbara

Published
2023
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38. Resting state functional brain networks associated with emotion processing in frontotemporal lobar degeneration

Author

Canu, Elisa, Calderaro, Davide, Castelnovo, Veronica, Basaia, Silvia, Magno, Maria Antonietta, Riva, Nilo, Magnani, Giuseppe, Caso, Francesca, Caroppo, Paola, Prioni, Sara, Villa, Cristina, Pain, Debora, Mora, Gabriele, Tremolizzo, Lucio, Appollonio, Ildebrando, Poletti, Barbara, Silani, Vincenzo, Filippi, Massimo, and Agosta, Federica

Published
2022
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44. Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative data

Author

Conca, Francesca, Esposito, Valentina, Rundo, Francesco, Quaranta, Davide, Muscio, Cristina, Manenti, Rosa, Caruso, Giulia, Lucca, Ugo, Galbussera, Alessia Antonella, Di Tella, Sonia, Baglio, Francesca, L’Abbate, Federica, Canu, Elisa, Catania, Valentina, Filippi, Massimo, Mattavelli, Giulia, Poletti, Barbara, Silani, Vincenzo, Lodi, Raffaele, De Matteis, Maddalena, Stanzani Maserati, Michelangelo, Arighi, Andrea, Rotondo, Emanuela, Tanzilli, Antonio, Pace, Andrea, Garramone, Federica, Cavaliere, Carlo, Pardini, Matteo, Rizzetto, Cristiano, Sorbi, Sandro, Perri, Roberta, Tiraboschi, Pietro, Canessa, Nicola, Cotelli, Maria, Ferri, Raffaele, Weintraub, Sandra, Marra, Camillo, Tagliavini, Fabrizio, Catricalà, Eleonora, and Cappa, Stefano Francesco

Published
2022
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46. QSM-detected iron accumulation in the cerebellar gray matter is selectively associated with executive dysfunction in non-demented ALS patients.

Author

Aiello, Edoardo Nicolò, Contarino, Valeria Elisa, Conte, Giorgio, Solca, Federica, Curti, Beatrice, Maranzano, Alessio, Torre, Silvia, Casale, Silvia, Doretti, Alberto, Colombo, Eleonora, Verde, Federico, Silani, Vincenzo, Chunlei Liu, Cinnante, Claudia, Triulzi, Fabio Maria, Morelli, Claudia, Poletti, Barbara, and Ticozzi, Nicola

Subjects
EXECUTIVE function, AMYOTROPHIC lateral sclerosis, GRAY matter (Nerve tissue), MEMORY span, CEREBELLAR cortex
Abstract

Background: This study aimed to assess whether quantitative susceptibility imaging (QSM)-based measures of iron accumulation in the cerebellum predict cognitive and behavioral features in non-demented amyotrophic lateral sclerosis (ALS) patients. Methods: A total of ALS patients underwent 3-T MRI and a clinical assessment using the ALS Functional Rating Scale-Revised (ALSFRS-R) and the Edinburgh Cognitive and Behavioural ALS Screen (ECAS). Regression models were applied to each subscale of the cognitive section of the ECAS and the ECASCarer Interview to examine the effect of QSM-based measures in white and gray matter (WM; GM) of the cerebellum, separately for right, left, and bilateral cerebellar regions of interest (ROIs). These effects were compared to those of cerebellar volumetrics in WM/GM, right and left hemispheres while controlling for demographics, disease status, and total intracranial volume. Results: Higher QSM measures of the cerebellar GM on the left, right, and bilateral sides significantly predicted (ps = 0.003) a greater number of errors on the executive functioning (EF) subscale of the ECAS (ECAS-EF). Moreover, higher GM-related, QSM measures of the cerebellum were associated with an increased probability of a below-cut-off performance on the ECAS-EF (ps = 0.024). No significant effects were observed for QSM measures of the cerebellar WM or for volumetric measures on the ECAS-EF. Other ECAS measures showed no significant effects. Bilateral QSM measures of the cerebellar GM also selectively predicted performance on backward digit span and social cognition tasks. Discussion: Iron accumulation within the cerebellar GM, particularly in the cerebellar cortices, may be associated with executive functioning deficits in nondemented ALS patients. Therefore, QSM-based measures could be useful for identifying the neural correlates of extra-motor cognitive deficits in ALS patients. [ABSTRACT FROM AUTHOR]

Published
2024
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47. Behavioral Alterations of Spatial Cognition and Role of the Apolipoprotein E-ε4 in Patients with MCI Due to Alzheimer's Disease: Results from the BDSC-MCI Project.

Author

Cammisuli, Davide Maria, Bellocchio, Virginia, Milesi, Alessandra, Aiello, Edoardo Nicolò, Poletti, Barbara, Verde, Federico, Silani, Vincenzo, Ticozzi, Nicola, Marchesi, Gloria, Granese, Valentina, Vignati, Benedetta, Isella, Valeria, Zago, Stefano, Difonzo, Teresa, Pomati, Simone, Porta, Giovanni, Cattaldo, Stefania, Mauro, Alessandro, and Castelnuovo, Gianluca

Subjects
ALZHEIMER'S disease, WALKING speed, SPATIAL behavior, MOBILE apps, COGNITION disorders
Abstract

Background: Beyond memory deterioration, spatial disorientation may occur along the continuum of normal aging—dementia of Alzheimer's type. The present study aims at detecting behavioral disorders of spatial cognition in prodromal Alzheimer's disease (AD) and verifying the association between Apolipoprotein E-ε4 (ApoE-ε4) genotype and gait patterns during a real-world naturalistic task. Methods: A sample of 58 elderly participants, of which 20 patients with mild cognitive impairment with CFS biomarker evidence of AD, 23 individuals with subjective cognitive decline (SCD), and 15 healthy controls (HCs), was tested by a modified version of the Detour Navigation Test (DNT-mv). Generalized linear models were run to explore the association between group belonging and wrong turns (WTs)/moments of hesitation (MsH) as behavioral disorientation scores of the DNT-mv as well as the effect of ApoE-ε4 genotype on time and walking speed registered by a smartphone app providing GPS tracking of body movement around urban environments. Results: Patients with MCI due to AD reported more WTs than individuals with SCD and HCs. Further, the ApoE-ε4 genotype determined a lower capacity in spatial information processing, influencing gait during naturalistic spatial navigation tasks. Conclusions: Behavior alterations of spatial cognition can be detected ecologically in prodromal AD. The use of technological solutions supporting gait analysis may help in corroborating the experimental observation. [ABSTRACT FROM AUTHOR]

Published
2024
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48. Association of APOE genotype and cerebrospinal fluid Aβ and tau biomarkers with cognitive and motor phenotype in amyotrophic lateral sclerosis.

Author

Maranzano, Alessio, Verde, Federico, Dubini, Antonella, Torre, Silvia, Colombo, Eleonora, Doretti, Alberto, Gentile, Francesco, Manini, Arianna, Milone, Ilaria, Brusati, Alberto, Peverelli, Silvia, Santangelo, Serena, Spinelli, Edoardo Gioele, Torresani, Erminio, Gentilini, Davide, Messina, Stefano, Morelli, Claudia, Poletti, Barbara, Agosta, Federica, and Ratti, Antonia

Abstract

Objective: Little is known about amyotrophic lateral sclerosis (ALS)‐nonspecific cognitive deficits – most notably memory disturbance – and their biological underpinnings. We investigated the associations of the Alzheimer's disease (AD) genetic risk factor APOE and cerebrospinal fluid (CSF) biomarkers Aβ and tau proteins with cognitive and motor phenotype in ALS. Methods: APOE haplotype was determined in 281 ALS patients; for 105 of these, CSF levels of Aβ42, Aβ40, total tau (T‐tau), and phosphorylated tau (P‐tau181) were quantified by chemiluminescence enzyme immunoassay (CLEIA). The Edinburgh Cognitive and Behavioural ALS Screen (ECAS) was employed to evaluate the neuropsychological phenotype. Results: APOE‐E4 allele was associated with worse ECAS memory score (median, 14.0 in carriers vs. 16.0 in non‐carriers) and lower CSF Aβ42 (−0.8 vs. 0.1, log‐transformed values) and Aβ42/40 ratio (−0.1 vs. 0.3). Some 37.1% of ALS patients showed low Aβ42 levels, possibly reflecting cerebral Aβ deposition. While lower Aβ42/40 correlated with lower memory score (β = 0.20), Aβ42 positively correlated with both ALS‐specific (β = 0.24) and ALS‐nonspecific (β = 0.24) scores. Although Aβ42/40 negatively correlated with T‐tau (β = −0.29) and P‐tau181 (β = −0.33), we found an unexpected positive association of Aβ42 and Aβ40 with both tau proteins. Regarding motor phenotype, lower levels of Aβ species were associated with lower motor neuron (LMN) signs (Aβ40: β = 0.34; Aβ42: β = 0.22). Conclusions: APOE haplotype and CSF Aβ biomarkers are associated with cognitive deficits in ALS and particularly with memory impairment. This might partly reflect AD‐like pathophysiological processes, but additional ALS‐specific mechanisms could be involved. [ABSTRACT FROM AUTHOR]

Published
2024
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