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Alpha-lipoic acid is a widely used medication that does not need a prescription. Although it is safely used in adults, hitherto no safe dose for children has been reported, and there is no known antidote. The medical literature provides four reports of alpha-lipoic acid intoxication in the pediatric population to date. This case-report is the lowest known dose of alpha-lipoic acid intake leading to poisoning in a teenager.

Dear Editor, Polat et al. (1) described nicely the clinical picture, management plan, and favorable outcome of a case of alpha-lipoic acid (ALA) intoxication in a 16-year-old Turkish girl. On the basis of her medical history, Polat et al. (1) mentioned that the patient took three pills, each of 600 mg ALA, approximately 2 hours before hospital admission to self-treat her headache with intervals of half an hour. I assume that the claimed self-treatment should not mask the potential suicidal attempt in the studied patient. Worldwide, suicide and suicide attempts are important health risks among adolescents with grave consequences (2). In an interesting Turkish study involving medico-legal autopsy cases, childhood and adolescent (aged 0-18 years) deaths constituted 24.4% of all cases. Suicide was the origin of death in 13.4% of cases recruiting victims aged

Dear Editor, First of all, we would like to thank our esteemed colleague for his/her criticism and for providing the opportunity to illuminate the point we did not emphasize in our article. WOS:000624295100015 34286330

Alpha-lipoic acid is a widely used medication that does not need a pre-scription. Although it is safely used in adults, hitherto no safe dose for children has been reported, and there is no known antidote. The med-ical literature provides four reports of alpha-lipoic acid intoxication in the pediatric population to date. This case-report is the lowest known dose of alpha-lipoic acid intake leading to poisoning in a teenager. WOS:000580388500019 33061765 Q4

Phosphine gas is a gas that is frequently used as rodenticide and insecticide due to its high diffusion capacity and the absence of residues in agricultural products. Since this gas is highly toxic, it is found in our country as aluminum phosphite tablets impregnated with clay, these tablets emit phosphine gas when they meet with the moisture in the air or gastric hydrochloric acid. Mortality rates in aluminum phosphite intoxications are 40-80% depending on the exposure dose. There is no control mechanism in the supply of aluminum phosphide tablets which are so dangerous and no information is given about the serious conditions that may occur during the use of these tablets. A 2 month old baby, whose family practiced drying pepper-eggplant, was reported to have been exposed to phosphine gas by inhalation, admitted to hospital with vomiting and cyanosis and lost his life within 24 hours. We present our case, who lost his life due to erroneous usage of aluminum phosphite, with additional emphasis on early diagnosis, treatment and gathering sample for toxicologic analysis, with corresponding forensic and medical documents. Fosfin gazı difüzyon kapasitesinin yüksek olmasından ve tarımsal ürünlerde kalıntı bırakmamasından dolayı rodentisit ve insektisit olarak sıklıkla kullanılan bir gazdır. Bu gaz oldukça toksik olduğundan preparat olarak kile emdirilmiş alüminyum fosfit tabletleri olarak ülkemizde bulunmakta, bu tabletler havadaki nem ya da mide de hidroklorik asit ile karşılaştığında fosfin gazı ortaya çıkmaktadır. Maruz kalınan doza bağımlı olarak alüminyum fosfit intoksikasyonlarında mortalite oranları %40-80 olarak belirtilmiştir. Bu kadar tehlikeli olan alüminyum fosfit tabletlerinin temininde ülkemizde herhangi bir kontrol mekanizması olmadığı gibi bu tabletlerin kullanımı sırasında oluşabilecek ciddi durumlar hakkında herhangi bir bilgilendirme de yapılmamaktadır. Ailesi biber-patlıcan kurutuculuğu yapan 2 aylık bebeğin inhalasyon yoluyla fosfin gazına maruz kaldığı, kusma ve morarma şikayetleriyle hastaneye kaldırıldığı ve 24 saat içerisinde hayatını kaybettiği bildirilmiştir. Bilinçsiz kullanılan alüminyum fosfite bağlı gelişen intoksikasyon sonucu hayatını kaybeden olgumuzu erken tanı-tedavinin ve toksikolojik inceleme için örnek alımının önemi vurgulanarak adli ve tıbbi belgeler eşliğinde sunuldu

Fosfin gazı difüzyon kapasitesinin yüksek olmasındanve tarımsal ürünlerde kalıntı bırakmamasından dolayı rodentisit ve insektisitolarak sıklıkla kullanılan bir gazdır. Bu gaz oldukça toksik olduğundanpreparat olarak kile emdirilmiş alüminyum fosfit tabletleri olarak ülkemizdebulunmakta, bu tabletler havadaki nem ya da mide de hidroklorik asit ilekarşılaştığında fosfin gazı ortaya çıkmaktadır. Maruz kalınan doza bağımlıolarak alüminyum fosfit intoksikasyonlarında mortalite oranları %40-80 olarakbelirtilmiştir. Bu kadar tehlikeli olan alüminyum fosfit tabletlerinintemininde ülkemizde herhangi bir kontrol mekanizması olmadığı gibi butabletlerin kullanımı sırasında oluşabilecek ciddi durumlar hakkında herhangibir bilgilendirme de yapılmamaktadır. Ailesibiber-patlıcan kurutuculuğu yapan 2 aylık bebeğin inhalasyon yoluyla fosfingazına maruz kaldığı, kusma ve morarma şikayetleriyle hastaneye kaldırıldığı ve24 saat içerisinde hayatını kaybettiği bildirilmiştir. Bilinçsiz kullanılanalüminyum fosfite bağlı gelişen intoksikasyon sonucu hayatını kaybeden olgumuzuerken tanı-tedavinin ve toksikolojik inceleme için örnek alımının önemi vurgulanarakadli ve tıbbi belgeler eşliğinde sunuldu, Phosphine gas is agas that is frequently used as rodenticide and insecticide due to its highdiffusion capacity and the absence of residues in agricultural products. Sincethis gas is highly toxic, it is found in our country as aluminum phosphitetablets impregnated with clay, these tablets emit phosphine gas when they meetwith the moisture in the air or gastric hydrochloric acid. Mortality rates inaluminum phosphite intoxications are 40-80% depending on the exposure dose.There is no control mechanism in the supply of aluminum phosphide tablets whichare so dangerous and no information is given about the serious conditions thatmay occur during the use of these tablets.A 2 month old baby,whose family practiced drying pepper-eggplant, was reported to have beenexposed to phosphine gas by inhalation, admitted to hospital with vomiting andcyanosis and lost his life within 24 hours. We present our case, who lost hislife due to erroneous usage of aluminum phosphite, with additional emphasis onearly diagnosis, treatment and gathering sample for toxicologic analysis, withcorresponding forensic and medical documents.

ÖZETLOJİSTİK ŞİRKETLERDE MUHASEBE ORGANİZASYONU VE LOJİSTİK MALİYETLER, UYGULAMALARHızın ve etkinliğin önemli olduğu günümüz rekabet koşullarında işletmeler, maliyetlerini düşürüp müşterilerin beklentilerini karşılayarak varlıklarını sürdürmeye çalışmaktadırlar. Maliyetlerin içinde en büyük paya sahip unsurlardan biri de lojistik maliyetlerdir. İşletmeler bu lojistik maliyetleri indirebilmek için bu maliyetleri oluşturan unsurları ve bunlar arasındaki etkileşimleri bilmeli ve sistem yaklaşımı içinde bir bütün olarak takip etmelidir. Bu da işletmelerde etkin bir muhasebe organizasyonunu gerektirmektedir. Bu sayede gerçekçi, güvenilir ve doğru bilgiler elde edilerek işletmenin hayati kararları bu bilgilere göre verilmektedir. Bu da rekabetin, işletmelerin lojistik maliyetlerini oluşturan lojistik faaliyetleri arasında olduğunu göstermektedir. ABSTRACTACCOUNTING ORGANISATIONS IN LOGISTIC COMPANIES AND LOGISTICAL COSTS, APPLICATIONSIn today' s competitive world, being fast and active are important for exploitation companies. Reducing the costs, they try to survive with meeting their customers’ expectations. One of the largest sized components among the costs is logistical costs. In order to reduce these logistical costs, exploitation companies need to be aware of the components, and their interaction and they need to operate with system approach. This requires an effective accounting organisation in exploitation companies. Consequently; with getting realistic, dependable, and accurate information, they can adopt vital decisions. This shows competing is among the logistical actions which construct logistical costs.

Objectives: Traffic accidents, falls, assaults, occupational accidents, intoxications, burns, electric shock, lightning strike, all cases of asphyxia, penetrating and firearm injuries, suspected or definite cases of sexual abuse, and suicide attempts should be evaluated in the forensic category. In this study, we aimed to present our intensive care experiences in forensic cases. Methods: We retrospectively evaluated forensic cases admitted to our Pediatric Intensive Care Unit between 1 February 2017 and 1 September 2018. Results: This study included 153 children, 65 (42.5%) boys and 88 (57.5%) girls. The forensic causes of hospitalizations in the intensive care unit included drug intoxication with a rate of 54.9%, followed by suicide attempts with 24.2%, falling from a high place with 5.2%, child abuse with 5.2%, pedestrian (out-of-vehicle) traffic accidents with 2.6%, drowning in water with 2.6%, road (in-vehicle) traffic accidents with 2%, electric shocks with 2%, and CO (carbon monoxide) poisoning with 1.3%. The drug intoxication was caused by drugs prescribed to the mother and the child with a rate of 40.6% and 27.1%, respectively. Analgesic anti-inflammatory drugs (33.1%) and antidepressant drugs (22.3%) were identified as major causes of intoxication. In addition, paracetamol was the most common cause of intoxication, with a rate of 21.9% among all intoxication cases and 72.5% in the analgesic group. Amitriptyline was the most common agent in the antidepressant group (59.2%). The admission rate to the intensive care unit between 08:00 and 14:00 was 35.1% for suicide attempts and 16.4% for non-suicide attempts, with a statistically significant difference (p=0.025; p