Search

Your search keyword '"Poirel, Laurent"' showing total 2,390 results
Start Over Author "Poirel, Laurent"
2,390 results on '"Poirel, Laurent"'

1. Rapid Detection of Ceftazidime/Avibactam Susceptibility/Resistance in Enterobacterales by Rapid CAZ/AVI NP Test

Author

Nordmann, Patrice, Bouvier, Maxime, Delaval, Adam, Tinguely, Camille, Poirel, Laurent, and Sadek, Mustafa

Subjects
Laboratory equipment, Laboratories -- Equipment and supplies, Ceftaroline, Glucose metabolism, Health
Abstract

Ceftazidime/avibactam (CAZ/AVI), approved for clinical use in 2015, is among the latest generation of commercialized antimicrobial drugs offering a valuable feature of being active against many types of carbapenem-resistant, gram-negative [...]

Published
2024
Full Text
View/download PDF

12. Pseudomonasaeruginosa antimicrobial susceptibility profiles, resistance mechanisms and international clonal lineages: update from ESGARS-ESCMID/ISARPAE Group

Author

Oliver, Antonio, Rojo-Molinero, Estrella, Arca-Suarez, Jorge, Beşli, Yeşim, Bogaerts, Pierre, Cantón, Rafael, Cimen, Cansu, Croughs, Peter D., Denis, Olivier, Giske, Christian G., Graells, Tíscar, Daniel Huang, Te-Din, Iorga, Bogdan I., Karatuna, Onur, Kocsis, Béla, Kronenberg, Andreas, López-Causapé, Carla, Malhotra-Kumar, Surbhi, Martínez, Luis Martínez, Mazzariol, Annarita, Meyer, Sylvain, Naas, Thierry, Notermans, Daan W., Oteo-Iglesias, Jesús, Pedersen, Torunn, Pirš, Mateja, Poeta, Patricia, Poirel, Laurent, Pournaras, Spyros, Sundsfjord, Arnfinn, Szabó, Dora, Tambić-Andrašević, Arjana, Vatcheva-Dobrevska, Rossitza, Vitkauskienė, Astra, and Jeannot, Katy

Published
2024
Full Text
View/download PDF

19. Contributors

Author

Aasly, Kurt, primary, Abós-Herràndiz, Rafael, additional, Ainsworth, Gillian B., additional, Alaba, Maria Retchie, additional, Alarcon, Rowell, additional, Alcantara-Creencia, Lota, additional, Allué, Rosario, additional, Almohammadi, Doha Saad A., additional, Aludia, Geofrey M., additional, Aludia, Phoebejean H., additional, Ang, Li Wei, additional, Antunes, Edith M., additional, Ariffin, Wan Nur Syazana Wan Mohamad, additional, Aruta, John Jamir Benzon R., additional, Backe, Karen Herrero, additional, Backer, Lorraine C., additional, Badaruddin, Hishamuddin, additional, Belgrano, Andrea, additional, Benkendorff, Kirsten, additional, Bennett, Baylin, additional, Bennett, Nathan, additional, Berdalet, Elisa, additional, Beukes, Denzil R., additional, Bienfait, André Marcel, additional, Blackford, Krysten, additional, Botta, Robert D., additional, Bouley, Timothy A., additional, Bridge, Nicola L., additional, Britton, Easkey, additional, Broad, Kenneth, additional, Brooks, Bryan W., additional, Buchan, Pamela M., additional, Callwood, Karlisa, additional, Canonico, Gabrielle, additional, Carić, Hrvoje, additional, Carlarne, Cinnamon Piñon, additional, Caro-Diaz, Eduardo J.E., additional, Carreño, Arnau, additional, Carvalho, Matthew, additional, Champion, Curtis, additional, Chassignet, Eric P., additional, Chen, Celia, additional, Chinain, Mireille, additional, Coffey, Kara, additional, Coleman, Melinda A, additional, Colom, Imma, additional, Court, Christa, additional, Cowan, Emily, additional, Crummy, Aoife, additional, Cui, Lin, additional, Cunningham, Emily G., additional, Cunsolo, Ashlee, additional, Cutter, Jeffery, additional, Da Costa, Paulo Martins, additional, Dankel, Dorothy J., additional, Darius, H. Taiana, additional, Davies, Adesina David, additional, Depledge, Michael H., additional, DeTomaso, Anthony W., additional, Devine, Dympna, additional, Dumbili, E., additional, Dupont, Sam, additional, Ellefmo, Steinar Løve, additional, Elmore II, Brockway, additional, Enciso, Olga, additional, Estenik, John, additional, Fabro, Keith Anthony, additional, Falkenberg, Laura J, additional, Fielding, Russell, additional, Fleming, Lora E., additional, Foltz, Kathleen, additional, Fontdecaba, Eva, additional, Forbes, Vivian Louis, additional, Gajardo, Lea Janine A., additional, Gascons, Ramon, additional, Gaspers, Anne, additional, Gatti, Clémence M.I., additional, Gedoria, Gerlie, additional, Gerwick, William H., additional, Gin, Karina Yew-Hoong, additional, Giner, Francesc, additional, Gleason, Michelle E., additional, Goh, Hong Ching, additional, Goh, Shin Giek, additional, Gómez, Sílvia, additional, Gonzales, Benjamin J., additional, Gordon, Vanessa, additional, Gribble, Matthew O., additional, Ha, Nguyen Thu, additional, Hamdoun, Amro, additional, Hamzah, B.A., additional, Hansen, Dorte, additional, Hara, Jenevieve, additional, Hargraves, Joshua, additional, Harper, Sherilee, additional, Henderson, Lesley, additional, Hien, Vu Thuc, additional, Higley, Kathryn A., additional, Hixson, Richard, additional, Hollenbeck, Julie, additional, Izquierdo, Angel, additional, Jacquet, Jennifer, additional, Jahateh, Betty, additional, Jalover-Par, Cherry Lyn, additional, James, Rathunam Arthur, additional, Johari, Sofia, additional, Jong, Mui Choo, additional, Joyce, Patrick WS, additional, Jungwiwattanaporn, Megan, additional, Justine, Eva Vivian, additional, Kawabe, Larissa A., additional, Keast, Jake, additional, Kelsey, R. Heath, additional, Kieszak, Stephanie, additional, Kirkpatrick, Barbara, additional, Kjørholt, Anne Trine, additional, Koeneke, Roberto, additional, Koh, Han Fang, additional, Kuit, Sui Hyang, additional, Kustka, Stephen, additional, Lavery, Amy, additional, Lee, Kwai Han, additional, Li, Wenxuan, additional, Lin, Raymond Tzer Pin, additional, Lin, Yijun, additional, Lloret, Josep, additional, Lloveras, Montse, additional, Lohmann, Rainer, additional, Lopes, Natalia Pirani Ghilardi, additional, Macdonald, Catherine, additional, Machalaba, Catherine, additional, Madarcos, John Roderick V., additional, Madarcos, Karen Gabalez, additional, Maharja, Carya, additional, Manfredi, Juan Luis, additional, Marathe, Nachiket P., additional, Marshall, Jamie, additional, Mas, Lluïsa, additional, Mason, Robert, additional, Mathis, Jeremy, additional, Maycock, Bruce, additional, McKinney, Raiana, additional, Middleton, Jacqueline, additional, Mills, David Jonathan, additional, Mindan, Montse, additional, Minuto, Stefania, additional, Moore, Amelia, additional, Morris, George, additional, Mugau, Sharon Mansarah, additional, Muir, Derek, additional, Muthukumar, Krishnan, additional, Narchi, Nemer E., additional, Newmyer, Jillian, additional, Newton, John N., additional, Ng, Charmaine, additional, Nimje, Priyank S., additional, Nordmann, Patrice, additional, O’Halloran, Chris, additional, Oftebro, Thea Lurås, additional, Olugbemi, Peter Wusu, additional, OOi, Peng Lim, additional, Owoade, Folasade Mary, additional, Pahl, Sabine, additional, Patil, Bodhi, additional, Pita, Pablo, additional, Plana, Joan, additional, Poirel, Laurent, additional, Poo, Kelly, additional, Porter, Dwayne E., additional, Portsmouth, Linda, additional, Pouso, Sarai, additional, Praet, Estelle, additional, Praptiwi, Radisti A., additional, Pratt, Dawn O., additional, Rabbottini, Lauren, additional, Radisic, Vera, additional, Ramage, Dan W., additional, Raps, Hervé, additional, Reich, Andrew, additional, Richter, Isabel, additional, Roberts, Virginia A., additional, Roué, Mélanie, additional, Saine, Dawda Foday, additional, Sajorne, Recca E., additional, San, Joan, additional, Sandifer, Paul A., additional, Scanes, Elliot, additional, Schnall, Amy H., additional, Schofield, John, additional, Schwacke, Lori H., additional, Scott, Geoffrey I., additional, Shalders, Tanika C, additional, Simões, Roméo Rocha, additional, Solo-Gabriele, Helena, additional, Songco, Angelique M., additional, Sowman, Georgie J., additional, Stephan, Wendy Blair, additional, Stricker, Adam, additional, Stumpf, Richard P., additional, Sumaila, Ussif Rashid, additional, Tan, Lik Tong, additional, Tan, Shermin, additional, Taufek, Norhidayah Mohd, additional, Teicher, Sam, additional, Tester, Patricia A., additional, Thao, Le Ngoc, additional, Then, Amy Yee-Hui, additional, Thiel, Martin, additional, Tong, Xuneng, additional, Tow, Charlene, additional, Trainer, Vera, additional, Turra, Alexander, additional, Uyarra, María C., additional, Vendrell, Cristina, additional, Vert, Cristina, additional, Vigar, Marissa, additional, Vignesh, Sivanandham, additional, Villasante, Sebastian, additional, Voronkova, Anastasia, additional, Wester, Julia, additional, Wowk, Katya, additional, Wozniak, Esther, additional, Wulandari, Prawesti, additional, Wyles, Kayleigh J., additional, Yu, Pei Lin, additional, and Zhang, Yiwen, additional

Published
2023
Full Text
View/download PDF

30. New Delhi Metallo-[beta]-Lactamase--Producing Enterobacterales Bacteria, Switzerland, 2019-2020

Author

Findlay, Jacqueline, Poirel, Laurent, Kessler, Julie, Kronenberg, Andreas, and Nordmann, Patrice

Subjects
Beta lactamases -- Health aspects, Enterobacteriaceae infections -- Diagnosis -- Care and treatment, Health
Abstract

Carbapenem-resistant Enterobacterales (CRE) bacteria are considered by the World Health Organization to be a critical global health concern; they were placed in the organization's critical-priority group of the priority pathogens [...]

Published
2021
Full Text
View/download PDF

32. Structure of the catalytic domain of the colistin resistance enzyme MCR-1

Author

Stojanoski, Vlatko, Sankaran, Banumathi, Prasad, BV Venkataram, Poirel, Laurent, Nordmann, Patrice, and Palzkill, Timothy

Subjects
Biochemistry and Cell Biology, Biological Sciences, Prevention, Vaccine Related, Biodefense, Infectious Diseases, Antimicrobial Resistance, Emerging Infectious Diseases, Infection, Developmental Biology
Abstract

BackgroundDue to the paucity of novel antibiotics, colistin has become a last resort antibiotic for treating multidrug resistant bacteria. Colistin acts by binding the lipid A component of lipopolysaccharides and subsequently disrupting the bacterial membrane. The recently identified plasmid-encoded MCR-1 enzyme is the first transmissible colistin resistance determinant and is a cause for concern for the spread of this resistance trait. MCR-1 is a phosphoethanolamine transferase that catalyzes the addition of phosphoethanolamine to lipid A to decrease colistin affinity.ResultsThe structure of the catalytic domain of MCR-1 at 1.32 Å reveals the active site is similar to that of related phosphoethanolamine transferases.ConclusionsThe putative nucleophile for catalysis, threonine 285, is phosphorylated in cMCR-1 and a zinc is present at a conserved site in addition to three zincs more peripherally located in the active site. As noted for catalytic domains of other phosphoethanolamine transferases, binding sites for the lipid A and phosphatidylethanolamine substrates are not apparent in the cMCR-1 structure, suggesting that they are present in the membrane domain.

Published
2016

33. Molecular analysis of metallo-beta-lactamase-producing Pseudomonas aeruginosa in Switzerland 2022-2023

Author

Findlay, Jacqueline; https://orcid.org/0000-0002-7335-9001, Raro, Otavio Hallal Ferreira, Poirel, Laurent, Nordmann, Patrice, NARA Network, Findlay, Jacqueline; https://orcid.org/0000-0002-7335-9001, Raro, Otavio Hallal Ferreira, Poirel, Laurent, Nordmann, Patrice, and NARA Network

Abstract

OBJECTIVES The occurrence of metallo-beta-lactamase-producing Pseudomonas aeruginosa (MBL-PA) isolates is increasing globally, including in Switzerland. The aim of this study was to characterise, phenotypically and genotypically, the MBL-PA isolates submitted to the Swiss National Reference Center for Emerging Antibiotic Resistance (NARA) reference laboratory over a 12-month period from July 2022 to July 2023. METHODS Thirty-nine non-duplicate MBL-PA Isolates were submitted to NARA over the study period from across Switzerland. Susceptibility was determined by broth microdilution according to EUCAST methodology. Whole-genome sequencing was performed on 34 isolates. Sequence types (STs) and resistance genes were ascertained using the Centre for Genomic Epidemiology platform. MBL genes, bla$_{NDM-1}$, bla$_{IMP-1}$, and bla$_{VIM-2}$, were cloned into vector pUCP24 and transformed into P. aeruginosa PA14. RESULTS The most prevalent MBL types identified in this study were VIM (21/39; 53.8%) followed by NDM (11/39; 28.2%), IMP (6/39; 15.4%), and a single isolate produced both VIM and NDM enzymes. WGS identified 13 different STs types among the 39 isolates. They all exhibited resistance to cephalosporins, carbapenems, and the beta-lactam-beta-lactamase inhibitor combinations, ceftolozane-tazobactam, ceftazidime-avibactam, imipenem-relebactam, and meropenem-vaborbactam, and 8 isolates were cefiderocol (FDC) resistant. Recombinant P. aeruginosa strains producing bla$_{NDM-1}$, bla$_{IMP-1}$, and bla$_{VIM-2}$ exhibited FDC MICs of 16, 8, and 1 mg/L, respectively. CONCLUSIONS This study showed that the MBL-PA in Switzerland could be attributed to the wide dissemination of high-risk clones that accounted for most isolates in this study. Although FDC resistance was only found in 8 isolates, MBL carriage was shown to be a major contributor to this phenotype.

Published
2024

Catalog

Books, media, physical & digital resources
See catalog results