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9 results on '"Pogoda, Michaela"'

1. Concept and feasibility of the Augsburg Longitudinal Plasma Study (ALPS) – a prospective trial for comprehensive liquid biopsy-based longitudinal monitoring of solid cancer patients

Author

Sommer Sebastian, Schmutz Maximilian, Hildebrand Kathrin, Schiwitza Annett, Benedikt Selinah, Eberle Maria, Mögele Tatiana, Sultan Aziz, Reichl Lena, Campillo Maria, Uhrmacher Luise, Nikolic Ana Antic, Bundschuh Ralph, Lapa Constantin, Kuhlen Michaela, Dintner Sebastian, Langer Angela, Märkl Bruno, Wendler Thomas, Tehlan Kartikay, Kröncke Thomas, Wahle Maria, Mann Matthias, Casadei Nicolas, Pogoda Michaela, Hummler Simone, Sax Irmengard, Schlesner Matthias, Kubuschok Boris, Trepel Martin, and Claus Rainer

Subjects
liquid biopsy, ctdna, longitudinal profiling, clonal evolution, spatial heterogeneity, translational research, Medical technology, R855-855.5
Abstract

Liquid biopsy (LBx) provides diagnostic, prognostic and predictive insights for malignant diseases and offers promising applications regarding tumor burden, tumor heterogeneity and clonal evolution.

Published
2024
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2. UV-radiation and MC1R germline mutations are risk factors for the development of conventional and spitzoid melanomas in children and adolescents

Author

Liebmann, Alexandra, Admard, Jakob, Armeanu-Ebinger, Sorin, Wild, Hannah, Abele, Michael, Gschwind, Axel, Seibel-Kelemen, Olga, Seitz, Christian, Bonzheim, Irina, Riess, Olaf, Demidov, German, Sturm, Marc, Schadeck, Malou, Pogoda, Michaela, Bien, Ewa, Krawczyk, Malgorzata, Jüttner, Eva, Mentzel, Thomas, Cesen, Maja, Pfaff, Elke, Kunc, Michal, Forchhammer, Stephan, Forschner, Andrea, Leiter-Stöppke, Ulrike, Eigentler, Thomas K., Schneider, Dominik T., Schroeder, Christopher, Ossowski, Stephan, and Brecht, Ines B.

Published
2023
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3. Platelet-Derived MicroRNAs Regulate Cardiac Remodeling After Myocardial Ischemia

Author

Philipp Schütte, Jan, Manke, Mailin-Christin, Hemmen, Katherina, Münzer, Patrick, Schörg, Barbara F., Campos Ramos, Gustavo, Pogoda, Michaela, Dicenta, Valerie, Hoffmann, Sabrina H.L., Pinnecker, Jürgen, Kollotzek, Ferdinand, Zdanyte, Monika, Müller, Karin A.L., Singh, Yogesh, Mack, Andreas F., Pichler, Bernd, Lang, Florian, Nieswandt, Bernhard, Gawaz, Meinrad, Heinze, Katrin G., Casadei, Nicolas, and Borst, Oliver

Published
2023
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4. Concept and feasibility of the Augsburg Longitudinal Plasma Study (ALPS) – a prospective trial for comprehensive liquid biopsy-based longitudinal monitoring of solid cancer patients

Author

Sommer, Sebastian, Schmutz, Maximilian, Hildebrand, Kathrin, Schiwitza, Annett, Benedikt, Selinah, Eberle, Maria, Mögele, Tatiana, Sultan, Aziz, Reichl, Lena, Campillo, Maria, Uhrmacher, Luise, Nikolic, Ana Antic, Bundschuh, Ralph, Lapa, Constantin, Kuhlen, Michaela, Dintner, Sebastian, Langer, Angela, Märkl, Bruno, Wendler, Thomas, Tehlan, Kartikay, Kröncke, Thomas, Wahle, Maria, Mann, Matthias, Casadei, Nicolas, Pogoda, Michaela, Hummler, Simone, Sax, Irmengard, Schlesner, Matthias, Kubuschok, Boris, Trepel, Martin, and Claus, Rainer

Published
2024
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5. Whole genome analysis of two sympatric human Mansonella: Mansonella perstans and Mansonella sp “DEUX”

Author

Rodi, Miriam, primary, Gross, Caspar, additional, Sandri, Thaisa Lucas, additional, Berner, Lilith, additional, Marcet-Houben, Marina, additional, Kocak, Ersoy, additional, Pogoda, Michaela, additional, Casadei, Nicolas, additional, Köhler, Carsten, additional, Kreidenweiss, Andrea, additional, Agnandji, Selidji Todagbe, additional, Gabaldón, Toni, additional, Ossowski, Stephan, additional, and Held, Jana, additional

Published
2023
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6. Platelet-Derived MicroRNAs Regulate Cardiac Remodeling After Myocardial Ischemia

Author

Schütte, Jan Philipp, primary, Manke, Mailin-Christin, additional, Hemmen, Katherina, additional, Münzer, Patrick, additional, Schörg, Barbara F., additional, Ramos, Gustavo Campos, additional, Pogoda, Michaela, additional, Dicenta, Valerie, additional, Hoffmann, Sabrina H.L., additional, Pinnecker, Jürgen, additional, Kollotzek, Ferdinand, additional, Zdanyte, Monika, additional, Mueller, Karin A.L., additional, Singh, Yogesh, additional, Mack, Andreas F., additional, Pichler, Bernd, additional, Lang, Florian, additional, Nieswandt, Bernhard, additional, Gawaz, Meinrad, additional, Heinze, Katrin G., additional, Casadei, Nicolas, additional, and Borst, Oliver, additional

Published
2023
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7. Antibody Response against SARS-CoV-2 and Seasonal Coronaviruses in Nonhospitalized COVID-19 Patients

Author

Ruetalo, Natalia, primary, Businger, Ramona, additional, Althaus, Karina, additional, Fink, Simon, additional, Ruoff, Felix, additional, Pogoda, Michaela, additional, Iftner, Angelika, additional, Ganzenmüller, Tina, additional, Hamprecht, Klaus, additional, Flehmig, Bertram, additional, Bakchoul, Tamam, additional, Templin, Markus F., additional, and Schindler, Michael, additional

Published
2021
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8. Single Molecule Molecular Inversion Probes for High Throughput Germline Screenings in Dystonia

Author

Pogoda, Michaela, Hilke, Franz-Joachim, Lohmann, E., Sturm, M., Lenz, F.A., Matthes, Jakob, Hoischen, A., Schroeder, C., and Grundmann, Kathrin

Subjects
All institutes and research themes of the Radboud University Medical Center, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]
Abstract

Contains fulltext : 214488.pdf (Publisher’s version ) (Open Access)

Published
2019

9. Single Molecule Molecular Inversion Probes for High Throughput Germline Screenings in Dystonia.

Author

Pogoda M, Hilke FJ, Lohmann E, Sturm M, Lenz F, Matthes J, Muyas F, Ossowski S, Hoischen A, Faust U, Sepahi I, Casadei N, Poths S, Riess O, Schroeder C, and Grundmann K

Abstract

Background: This study's aim was to investigate a large cohort of dystonia patients for pathogenic and rare variants in the ATM gene, making use of a new, cost-efficient enrichment technology for NGS-based screening. Methods: Single molecule Molecular Inversion Probes (smMIPs) were used for targeted enrichment and sequencing of all protein coding exons and exon-intron boundaries of the ATM gene in 373 dystonia patients and six positive controls with known ATM variants. Additionally, a rare-variant association study was performed. Results: One patient (0.3%) was compound heterozygous and 21 others were carriers of variants of unknown significance (VUS) in the ATM gene. Although mutations in sporadic dystonia patients are not common, exclusion of pathogenic variants is crucial to recognize a potential tumor predisposition syndrome. SmMIPs produced similar results as routinely used NGS-based approaches. Conclusion: Our results underline the importance of implementing ATM in the routine genetic testing of dystonia patients and confirm the reliability of smMIPs and their usability for germline screenings in rare neurodegenerative conditions., (Copyright © 2019 Pogoda, Hilke, Lohmann, Sturm, Lenz, Matthes, Muyas, Ossowski, Hoischen, Faust, Sepahi, Casadei, Poths, Riess, Schroeder and Grundmann.)

Published
2019
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