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456 results on '"Plemper, Richard K."'

1. The small molecule inhibitor of SARS-CoV-2 3CLpro EDP-235 prevents viral replication and transmission in vivo

Author

Rhodin, Michael H. J., Reyes, Archie C., Balakrishnan, Anand, Bisht, Nalini, Kelly, Nicole M., Gibbons, Joyce Sweeney, Lloyd, Jonathan, Vaine, Michael, Cressey, Tessa, Crepeau, Miranda, Shen, Ruichao, Manalo, Nathan, Castillo, Jonathan, Levene, Rachel E., Leonard, Daniel, Zang, Tianzhu, Jiang, Lijuan, Daniels, Kellye, Cox, Robert M., Lieber, Carolin M., Wolf, Josef D., Plemper, Richard K., Leist, Sarah R., Scobey, Trevor, Baric, Ralph S., Wang, Guoqiang, Goodwin, Bryan, and Or, Yat Sun

Published
2024
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2. Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets

Author

Cox, Robert M., Wolf, Josef D., Lieberman, Nicole A., Lieber, Carolin M., Kang, Hae-Ji, Sticher, Zachary M., Yoon, Jeong-Joong, Andrews, Meghan K., Govindarajan, Mugunthan, Krueger, Rebecca E., Sobolik, Elizabeth B., Natchus, Michael G., Gewirtz, Andrew T., deSwart, Rik L., Kolykhalov, Alexander A., Hekmatyar, Khan, Sakamoto, Kaori, Greninger, Alexander L., and Plemper, Richard K.

Published
2024
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6. 2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

Author

Kuhn, Jens H., Adkins, Scott, Alkhovsky, Sergey V., Avšič-Županc, Tatjana, Ayllón, María A., Bahl, Justin, Balkema-Buschmann, Anne, Ballinger, Matthew J., Bandte, Martina, Beer, Martin, Bejerman, Nicolas, Bergeron, Éric, Biedenkopf, Nadine, Bigarré, Laurent, Blair, Carol D., Blasdell, Kim R., Bradfute, Steven B., Briese, Thomas, Brown, Paul A., Bruggmann, Rémy, Buchholz, Ursula J., Buchmeier, Michael J., Bukreyev, Alexander, Burt, Felicity, Büttner, Carmen, Calisher, Charles H., Candresse, Thierry, Carson, Jeremy, Casas, Inmaculada, Chandran, Kartik, Charrel, Rémi N., Chiaki, Yuya, Crane, Anya, Crane, Mark, Dacheux, Laurent, Bó, Elena Dal, de la Torre, Juan Carlos, de Lamballerie, Xavier, de Souza, William M., de Swart, Rik L., Dheilly, Nolwenn M., Di Paola, Nicholas, Di Serio, Francesco, Dietzgen, Ralf G., Digiaro, Michele, Drexler, J. Felix, Duprex, W. Paul, Dürrwald, Ralf, Easton, Andrew J., Elbeaino, Toufic, Ergünay, Koray, Feng, Guozhong, Feuvrier, Claudette, Firth, Andrew E., Fooks, Anthony R., Formenty, Pierre B. H., Freitas-Astúa, Juliana, Gago-Zachert, Selma, García, María Laura, García-Sastre, Adolfo, Garrison, Aura R., Godwin, Scott E., Gonzalez, Jean-Paul J., de Bellocq, Joëlle Goüy, Griffiths, Anthony, Groschup, Martin H., Günther, Stephan, Hammond, John, Hepojoki, Jussi, Hierweger, Melanie M., Hongō, Seiji, Horie, Masayuki, Horikawa, Hidenori, Hughes, Holly R., Hume, Adam J., Hyndman, Timothy H., Jiāng, Dàohóng, Jonson, Gilda B., Junglen, Sandra, Kadono, Fujio, Karlin, David G., Klempa, Boris, Klingström, Jonas, Koch, Michel C., Kondō, Hideki, Koonin, Eugene V., Krásová, Jarmila, Krupovic, Mart, Kubota, Kenji, Kuzmin, Ivan V., Laenen, Lies, Lambert, Amy J., Lǐ, Jiànróng, Li, Jun-Min, Lieffrig, François, Lukashevich, Igor S., Luo, Dongsheng, Maes, Piet, Marklewitz, Marco, Marshall, Sergio H., Marzano, Shin-Yi L., McCauley, John W., Mirazimi, Ali, Mohr, Peter G., Moody, Nick J. G., Morita, Yasuaki, Morrison, Richard N., Mühlberger, Elke, Naidu, Rayapati, Natsuaki, Tomohide, Navarro, José A., Neriya, Yutaro, Netesov, Sergey V., Neumann, Gabriele, Nowotny, Norbert, Ochoa-Corona, Francisco M., Palacios, Gustavo, Pallandre, Laurane, Pallás, Vicente, Papa, Anna, Paraskevopoulou, Sofia, Parrish, Colin R., Pauvolid-Corrêa, Alex, Pawęska, Janusz T., Pérez, Daniel R., Pfaff, Florian, Plemper, Richard K., Postler, Thomas S., Pozet, Françoise, Radoshitzky, Sheli R., Ramos-González, Pedro L., Rehanek, Marius, Resende, Renato O., Reyes, Carina A., Romanowski, Víctor, Rubbenstroth, Dennis, Rubino, Luisa, Rumbou, Artemis, Runstadler, Jonathan A., Rupp, Melanie, Sabanadzovic, Sead, Sasaya, Takahide, Schmidt-Posthaus, Heike, Schwemmle, Martin, Seuberlich, Torsten, Sharpe, Stephen R., Shi, Mang, Sironi, Manuela, Smither, Sophie, Song, Jin-Won, Spann, Kirsten M., Spengler, Jessica R., Stenglein, Mark D., Takada, Ayato, Tesh, Robert B., Těšíková, Jana, Thornburg, Natalie J., Tischler, Nicole D., Tomitaka, Yasuhiro, Tomonaga, Keizō, Tordo, Noël, Tsunekawa, Kenta, Turina, Massimo, Tzanetakis, Ioannis E., Vaira, Anna Maria, van den Hoogen, Bernadette, Vanmechelen, Bert, Vasilakis, Nikos, Verbeek, Martin, von Bargen, Susanne, Wada, Jiro, Wahl, Victoria, Walker, Peter J., Whitfield, Anna E., Williams, John V., Wolf, Yuri I., Yamasaki, Junki, Yanagisawa, Hironobu, Ye, Gongyin, Zhang, Yong-Zhen, and Økland, Arnfinn Lodden

Published
2022
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8. Efficacy of late-onset antiviral treatment in immune-compromised hosts with persistent SARS-CoV-2 infection

Author

Lieber, Carolin M, primary, Kang, Hae-Ji, additional, Sobolik, Elizabeth B, additional, Sticher, Zachary M, additional, Ngo, Vu L, additional, Gewirtz, Andrew T., additional, Kolykhalov, Alexander A., additional, Natchus, Michael G, additional, Greninger, Alexander L., additional, Suthar, Mehul S, additional, and Plemper, Richard K., additional

Published
2024
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18. 539. Efficacy in Multiple SARS-CoV-2 Animal Models Supports Phase 3 Dose Selection for Obeldesivir

Author

Pitts, Jared, primary, Babusis, Darius, additional, Humeniuk, Rita, additional, Martinez, David, additional, Cox, Robert M, additional, Schäfer, Alexandra, additional, Riola, Nicholas C, additional, Feng, Joy, additional, Du Pont, Venice, additional, Anoshchenko, Olena, additional, Vermillion, Meghan, additional, Abdelghany, Mazin, additional, Hyland, Robert H, additional, Girish, Sandhya, additional, Sheahan, Timothy P, additional, Plemper, Richard K, additional, Baric, Ralph S, additional, Cihlar, Tomas, additional, Llewellyn, Joe, additional, Winter, Helen, additional, Bannister, Roy, additional, Subramanian, Raju, additional, Mackman, Richard L, additional, and Bilello, John P, additional

Published
2023
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22. Annual (2023) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota)

Author

National Institute of Allergy and Infectious Diseases (US), Antiviral Countermeasures Development Center (US), Department of Agriculture (US), Department of the Army (US), Department of Health and Human Services (US), US Department of Homeland Security, Federal Government of the United States, Kuhn, Jens H. [0000-0002-7800-6045], Abe, Junya [0000-0003-3627-7071], Adkins, Scott [0000-0003-0095-8414], Alkhovsky, Sergey V. [0000-0001-6913-5841], Avsic-Zupanc, Tatjana [0000-0001-6243-0688], Ayllón, María A. [0000-0001-7893-6106], Bahl, Justin [0000-0001-7572-4300], Balkema-Buschmann, A. [0000-0001-7613-9592], Ballinger, Matthew J. [0000-0001-7453-8725], Bejerman, Nicolas [0000-0002-7851-3506], Biedenkopf, Nadine [0000-0002-6061-8019], Blair, Carol D.[0000-0002-2803-0354], Blasdell, Kim R.[0000-0003-2121-0376], Bradfute, Steven B.[0000-0002-1985-751X], Briese, Thomas [0000-0002-4819-8963], Buchholz, Ursula J. [0000-0002-2329-3198], Buchmeier, Michael J.[0000-0002-2387-9287], Bukreyev, Alexander [0000-0002-0342-4824], Burt, Felicity [0000-0002-7238-7799], Büttner, Carmen [0000-0002-2086-2594], Calisher, Charles H. [0000-0003-0213-294X], Cao, Mengji [0000-0003-0396-262X], Casas, Inmaculada [0000-0003-1840-1198], Chandran, Kartik [0000-0003-0232-7077], Charrel, Rémi N.[0000-0002-7675-8251], Chaturvedi, Krishna Kumar [0000-0002-6529-5466], Crane, Anya [0000-0002-2060-2469], De Swart, Rik L.[0000-0003-3599-8969], Debat, Humberto [0000-0003-3056-3739], Dheilly, Nolwenn M.[0000-0002-3675-5013], Di Paola, Nicholas [0000-0002-9694-3913], Di Serio, Francesco [0000-0003-2822-704X], Dietzgen, Ralf G.[0000-0002-7772-2250], Digiaro, Michele [0009-0006-3089-3606], Drexler, J. Felix [0000-0002-3509-0232], Duprex, W. Paul [0000-0003-1716-6376], Elbeaino, Toufic [0000-0003-2211-7907], Ergünay, Koray [0000-0001-5422-1982], Feng, Guozhong [0000-0002-9489-9322], Fooks, Anthony R.[0000-0002-3243-6154], Formenty, Pierre B.H.[0000-0002-9482-5411], Freitas-Astúa, Juliana [0000-0002-0506-6880], Gago-Zachert, Selma [0000-0002-1084-2119], García, María Laura [0000-0001-6468-6943], Garrison, Aura R.[0000-0003-3034-6400], Gaskin, Thomas R. [0000-0002-5644-4431], Gouy de Bellocq, Joelle [0000-0001-5831-6284], Griffiths, Anthony [0000-0001-5435-8364], Groschup, M. H.[0000-0003-0215-185X], Günther, Stephan [0000-0002-6562-0230], Hayashi, Kazusa [0009-0002-9395-0066], Hepojoki, Jussi [0000-0001-5699-214X], Higgins, Colleen M. [0000-0001-9016-2940], Horie, Masayuki [0000-0003-4682-7698], Hughes, Holly R.[0000-0003-1380-8263], Hyndman, Timothy [0000-0002-7047-5023], Jiāng, Dàohóng [0000-0002-3862-7461], Jonson, Gilda B.[0000-0003-0097-8634], Junglen, Sandra [0000-0002-3799-6011], Klempa, B.[0000-0002-6931-1224], Klingström, Jonas [0000-0001-9076-1441], Kondō, Hideki [0000-0001-9220-5350], Koonin, Eugene V. [0000-0003-3943-8299], Krupovic, Mart [0000-0001-5486-0098], Kurath, Gael [0000-0003-3294-560X], Laenen, Lies [0000-0001-9118-8608], Li, Jianrong [0000-0002-7130-1084], Lukashevich, Igor S.[0000-0001-6523-5116], MacDiarmid, Robin M.[0000-0002-7057-2018], Maes, Piet [0000-0002-4571-5232], Marklewitz, Marco [0000-0003-1828-8770], Marshall, Sergio H.[0000-0003-0438-8252], Marzano, Shin-Yi L. [0000-0003-0548-3761], Mühlberger, Elke [0000-0003-3547-9376], Nabeshima, Tomoyuki [0000-0002-6570-096X], Naidu, Rayapati [0000-0002-7273-5116], Natsuaki, Tomohide [0000-0003-1823-7308], Navarro, José A. [0000-0002-0536-6074], Neriya, Yutaro [0000-0002-1385-0050], Netesov, Sergey V. [0000-0002-7786-2464], Neumann, Gabriele [0000-0001-7054-1775], Nowotny, N. [0000-0002-3548-571X], Ochoa-Corona, Francisco M. [0000-0002-4112-8209], Pallás, Vicente [0000-0003-4954-989X], Papa, Anna [0000-0002-6643-3322], Paraskevopoulou, Sofia [0000-0003-2608-2596], Parrish, Colin R. [0000-0002-1836-6655], Pauvolid-Corrêa, Alex [0000-0002-6924-157X], Pawęska, Janusz T. [0000-0001-8776-7519], Pérez, Daniel R. [0000-0002-6569-5689], Pfaff, Florian [0000-0003-0178-6183], Plemper, Richard K. [0000-0003-2034-2107], Postler, Thomas S. [0000-0002-3558-9084], Rabbidge, Lee O. [0009-0001-7962-4881], Radoshitzky, Sheli R. [0000-0001-8976-8056], Ramos-González, Pedro L. [0000-0002-9640-6587], Rehanek, Marius [0000-0002-5710-5060], Resende, Renato O. [0000-0003-3852-1576], Romanowski, Víctor [0000-0001-6378-7929], Rubbenstroth, Dennis [0000-0002-8209-6274], Rubino, Luisa [0000-0002-2073-2415], Runstadler, Jonathan A. [0000-0002-6747-7765], Sabanadzovic, Sead [0000-0002-2995-2633], Salvato, Maria S. [0000-0002-3357-5391], Sasaya, Takahide [0000-0002-5020-9377], Schwemmle, Martin [0000-0002-2972-6855], Shi, Mang [0000-0002-6154-4437], Shimomoto, Yoshifumi [0000-0002-0796-7068], Kavi Sidharthan, Venkidusamy [0000-0003-1561-549X], Sironi, Manuela [0000-0002-2267-5266], Smither, Sophie [0000-0002-7835-3581], Spann, Kirsten [0000-0003-0567-8382], Spengler, Jessica R. [0000-0002-5383-0513], Stenglein, Mark D. [0000-0002-0993-813X], Takada, Ayato [0000-0003-2464-6642], Takeyama, Sawana [0009-0000-3771-5999], Tesh, Robert B. [0000-0002-9226-397X], Thornburg, Natalie J. [0000-0003-3523-3616], Tischler, Nicole D. [0000-0002-4578-4780], Tomitaka, Yasuhiro [0000-0002-6914-4016], Tomonaga, Keizō [0000-0003-0405-7103], Tordo, Noël [0000-0001-5873-059X], Tu, Changchun [0000-0002-8134-7502], Turina, Massimo [0000-0002-9659-9470], Tzanetakis, Ioannis E. [0000-0002-5970-1763], Vaira, Anna Maria [0000-0003-2526-4419], Van den Hoogen, Bernadette [0000-0003-1996-8559], Vanmechelen, Bert [0000-0002-8350-4356], Verbeek, Martin [0000-0002-8973-3803], Von Bargen, Susanne [0000-0001-8321-1572], Wada, Jiro [0000-0001-9846-0846], Wahl, Victoria [0000-0002-6588-4308], Walker, Peter J. [0000-0003-1851-642X], Waltzek, Thomas B. [0000-0001-6383-5978], Whitfield, Anna E. [0000-0002-3538-015X], Wolf, Yuri I. [0000-0002-0247-8708], Xylogianni, Evanthia [0009-0001-8768-0939], Yanagisawa, Hironobu [0000-0002-6729-466X], Ye, Gongyin [0000-0003-4937-8867], Yuan, Zhiming [0000-0002-3234-9616], Zerbini, F. Murilo [0000-0001-8617-0200], Okland, Arnfinn Lodden [0000-0003-3062-4386], Kuhn, Jens H., Abe, Junya, Adkins, Scott, Alkhovsky, Sergey V., Avsic-Zupanc, Tatjana, Ayllón, María A., Bahl, Justin, Balkema-Buschmann, A., Ballinger, Matthew J., Kumar Baranwal, Virendra, Beer, Martin, Bejerman, Nicolas, Bergeron, Éric, Biedenkopf, Nadine, Blair, Carol D., Blasdell, Kim R., Blouin, Arnaud G., Bradfute, Steven B., Briese, Thomas, Brown, Paul A., Buchholz, Ursula J., Buchmeier, Michael J., Bukreyev, Alexander, Burt, Felicity, Büttner, Carmen, Calisher, Charles H., Cao, Mengji, Casas, Inmaculada, Chandran, Kartik, Charrel, Rémi N., Chaturvedi, Krishna Kumar, Chooi, Kar Mun, Crane, Anya, Dal Bó, Elena, de la Torre, J. C., de Souza, William Marciel, De Swart, Rik L., Debat, Humberto, Dheilly, Nolwenn M., Di Paola, Nicholas, Di Serio, Francesco, Dietzgen, Ralf G., Digiaro, Michele, Drexler, J. Felix, Duprex, W. Paul, Dürrwald, Ralf, Easton, Andrew J., Elbeaino, Toufic, Ergünay, Koray, Feng, Guozhong, Firth, Andrew E., Fooks, Anthony R., Formenty, Pierre B.H., Freitas-Astúa, Juliana, Gago-Zachert, Selma, García, María Laura, García-Sastre, Adolfo, Garrison, Aura R., Gaskin, Thomas R., Gong, Wenjie, Gonzalez, Jean-Paul J., Gouy de Bellocq, Joelle, Griffiths, Anthony, Groschup, M. H., Günther, Ines, Günther, Stephan, Hammond, John, Hasegawa, Yusuke, Hayashi, Kazusa, Hepojoki, Jussi, Higgins, Colleen M., Hongo, Seiji, Horie, Masayuki, Hughes, Holly R., Hume, Adam J., Hyndman, Timothy, Ikeda, Kenichi, Jiāng, Dàohóng, Jonson, Gilda B., Junglen, Sandra, Klempa, B., Klingström, Jonas, Kondō, Hideki, Koonin, Eugene V., Krupovic, Mart, Kubota, Kenji, Kurath, Gael, Laenen, Lies, Lambert, Amy J., Li, Jianrong, Li, Jun-Min, Liu, Ran, Lukashevich, Igor S., MacDiarmid, Robin M, Maes, Piet, Marklewitz, Marco, Marshall, Sergio H., Marzano, Shin-Yi L., McCauley, John W., Mirazimi, Ali, Mühlberger, Elke, Nabeshima, Tomoyuki, Naidu, Rayapati, Natsuaki, Tomohide, Navarro, Beatriz, Navarro, José A., Neriya, Yutaro, Netesov, Sergey V., Neumann, Gabriele, Nowotny, N., Nunes, Márcio R.T., Ochoa-Corona, Francisco M., Okada, Tomoyuki, Palacios, Gustavo, Pallás, Vicente, Papa, Anna, Paraskevopoulou, Sofia, Parrish, Colin R., Pauvolid-Corrêa, Alex, Pawęska, Janusz T., Pérez, Daniel R., Pfaff, Florian, Plemper, Richard K., Postler, Thomas S., Rabbidge, Lee O., Radoshitzky, Sheli R., Ramos-González, Pedro L., Rehanek, Marius, Resende, Renato O., Reyes, Carina A., Rodrigues, Thaís C.S., Romanowski, Víctor, Rubbenstroth, Dennis, Rubino, Luisa, Runstadler, Jonathan A., Sabanadzovic, Sead, Sadiq, Sabrina, Salvato, Maria S., Sasaya, Takahide, Schwemmle, Martin, Sharpe, Stephen R., Shi, Mang, Shimomoto, Yoshifumi, Kavi Sidharthan, Venkidusamy, Sironi, Manuela, Smither, Sophie, Song, Jin-Won, Spann, Kirsten, Spengler, Jessica R., Stenglein, Mark D., Takada, Ayato, Takeyama, Sawana, Tatara, Akio, Tesh, Robert B., Thornburg, Natalie J., Tian, Xin, Tischler, Nicole D., Tomitaka, Yasuhiro, Tomonaga, Keizō, Tordo, Noël, Tu, Changchun, Turina, Massimo, Tzanetakis, Ioannis E., Vaira, Anna Maria, Van den Hoogen, Bernadette, Vanmechelen, Bert, Vasilakis, Nikos, Verbeek, Martin, Von Bargen, Susanne, Wada, Jiro, Wahl, Victoria, Walker, Peter J., Waltzek, Thomas B., Whitfield, Anna E., Wolf, Yuri I., Xia, Han, Xylogianni, Evanthia, Yanagisawa, Hironobu, Yano, Kazutaka, Ye, Gongyin, Yuan, Zhiming, Zerbini, F. Murilo, Zhang, Guilin, Zhang, Song, Zhang, Yong-Zhen, Zhao, Lu, Okland, Arnfinn Lodden, National Institute of Allergy and Infectious Diseases (US), Antiviral Countermeasures Development Center (US), Department of Agriculture (US), Department of the Army (US), Department of Health and Human Services (US), US Department of Homeland Security, Federal Government of the United States, Kuhn, Jens H. [0000-0002-7800-6045], Abe, Junya [0000-0003-3627-7071], Adkins, Scott [0000-0003-0095-8414], Alkhovsky, Sergey V. [0000-0001-6913-5841], Avsic-Zupanc, Tatjana [0000-0001-6243-0688], Ayllón, María A. [0000-0001-7893-6106], Bahl, Justin [0000-0001-7572-4300], Balkema-Buschmann, A. [0000-0001-7613-9592], Ballinger, Matthew J. [0000-0001-7453-8725], Bejerman, Nicolas [0000-0002-7851-3506], Biedenkopf, Nadine [0000-0002-6061-8019], Blair, Carol D.[0000-0002-2803-0354], Blasdell, Kim R.[0000-0003-2121-0376], Bradfute, Steven B.[0000-0002-1985-751X], Briese, Thomas [0000-0002-4819-8963], Buchholz, Ursula J. [0000-0002-2329-3198], Buchmeier, Michael J.[0000-0002-2387-9287], Bukreyev, Alexander [0000-0002-0342-4824], Burt, Felicity [0000-0002-7238-7799], Büttner, Carmen [0000-0002-2086-2594], Calisher, Charles H. [0000-0003-0213-294X], Cao, Mengji [0000-0003-0396-262X], Casas, Inmaculada [0000-0003-1840-1198], Chandran, Kartik [0000-0003-0232-7077], Charrel, Rémi N.[0000-0002-7675-8251], Chaturvedi, Krishna Kumar [0000-0002-6529-5466], Crane, Anya [0000-0002-2060-2469], De Swart, Rik L.[0000-0003-3599-8969], Debat, Humberto [0000-0003-3056-3739], Dheilly, Nolwenn M.[0000-0002-3675-5013], Di Paola, Nicholas [0000-0002-9694-3913], Di Serio, Francesco [0000-0003-2822-704X], Dietzgen, Ralf G.[0000-0002-7772-2250], Digiaro, Michele [0009-0006-3089-3606], Drexler, J. Felix [0000-0002-3509-0232], Duprex, W. Paul [0000-0003-1716-6376], Elbeaino, Toufic [0000-0003-2211-7907], Ergünay, Koray [0000-0001-5422-1982], Feng, Guozhong [0000-0002-9489-9322], Fooks, Anthony R.[0000-0002-3243-6154], Formenty, Pierre B.H.[0000-0002-9482-5411], Freitas-Astúa, Juliana [0000-0002-0506-6880], Gago-Zachert, Selma [0000-0002-1084-2119], García, María Laura [0000-0001-6468-6943], Garrison, Aura R.[0000-0003-3034-6400], Gaskin, Thomas R. [0000-0002-5644-4431], Gouy de Bellocq, Joelle [0000-0001-5831-6284], Griffiths, Anthony [0000-0001-5435-8364], Groschup, M. H.[0000-0003-0215-185X], Günther, Stephan [0000-0002-6562-0230], Hayashi, Kazusa [0009-0002-9395-0066], Hepojoki, Jussi [0000-0001-5699-214X], Higgins, Colleen M. [0000-0001-9016-2940], Horie, Masayuki [0000-0003-4682-7698], Hughes, Holly R.[0000-0003-1380-8263], Hyndman, Timothy [0000-0002-7047-5023], Jiāng, Dàohóng [0000-0002-3862-7461], Jonson, Gilda B.[0000-0003-0097-8634], Junglen, Sandra [0000-0002-3799-6011], Klempa, B.[0000-0002-6931-1224], Klingström, Jonas [0000-0001-9076-1441], Kondō, Hideki [0000-0001-9220-5350], Koonin, Eugene V. [0000-0003-3943-8299], Krupovic, Mart [0000-0001-5486-0098], Kurath, Gael [0000-0003-3294-560X], Laenen, Lies [0000-0001-9118-8608], Li, Jianrong [0000-0002-7130-1084], Lukashevich, Igor S.[0000-0001-6523-5116], MacDiarmid, Robin M.[0000-0002-7057-2018], Maes, Piet [0000-0002-4571-5232], Marklewitz, Marco [0000-0003-1828-8770], Marshall, Sergio H.[0000-0003-0438-8252], Marzano, Shin-Yi L. [0000-0003-0548-3761], Mühlberger, Elke [0000-0003-3547-9376], Nabeshima, Tomoyuki [0000-0002-6570-096X], Naidu, Rayapati [0000-0002-7273-5116], Natsuaki, Tomohide [0000-0003-1823-7308], Navarro, José A. [0000-0002-0536-6074], Neriya, Yutaro [0000-0002-1385-0050], Netesov, Sergey V. [0000-0002-7786-2464], Neumann, Gabriele [0000-0001-7054-1775], Nowotny, N. [0000-0002-3548-571X], Ochoa-Corona, Francisco M. [0000-0002-4112-8209], Pallás, Vicente [0000-0003-4954-989X], Papa, Anna [0000-0002-6643-3322], Paraskevopoulou, Sofia [0000-0003-2608-2596], Parrish, Colin R. [0000-0002-1836-6655], Pauvolid-Corrêa, Alex [0000-0002-6924-157X], Pawęska, Janusz T. [0000-0001-8776-7519], Pérez, Daniel R. [0000-0002-6569-5689], Pfaff, Florian [0000-0003-0178-6183], Plemper, Richard K. [0000-0003-2034-2107], Postler, Thomas S. [0000-0002-3558-9084], Rabbidge, Lee O. [0009-0001-7962-4881], Radoshitzky, Sheli R. [0000-0001-8976-8056], Ramos-González, Pedro L. [0000-0002-9640-6587], Rehanek, Marius [0000-0002-5710-5060], Resende, Renato O. [0000-0003-3852-1576], Romanowski, Víctor [0000-0001-6378-7929], Rubbenstroth, Dennis [0000-0002-8209-6274], Rubino, Luisa [0000-0002-2073-2415], Runstadler, Jonathan A. [0000-0002-6747-7765], Sabanadzovic, Sead [0000-0002-2995-2633], Salvato, Maria S. [0000-0002-3357-5391], Sasaya, Takahide [0000-0002-5020-9377], Schwemmle, Martin [0000-0002-2972-6855], Shi, Mang [0000-0002-6154-4437], Shimomoto, Yoshifumi [0000-0002-0796-7068], Kavi Sidharthan, Venkidusamy [0000-0003-1561-549X], Sironi, Manuela [0000-0002-2267-5266], Smither, Sophie [0000-0002-7835-3581], Spann, Kirsten [0000-0003-0567-8382], Spengler, Jessica R. [0000-0002-5383-0513], Stenglein, Mark D. [0000-0002-0993-813X], Takada, Ayato [0000-0003-2464-6642], Takeyama, Sawana [0009-0000-3771-5999], Tesh, Robert B. [0000-0002-9226-397X], Thornburg, Natalie J. [0000-0003-3523-3616], Tischler, Nicole D. [0000-0002-4578-4780], Tomitaka, Yasuhiro [0000-0002-6914-4016], Tomonaga, Keizō [0000-0003-0405-7103], Tordo, Noël [0000-0001-5873-059X], Tu, Changchun [0000-0002-8134-7502], Turina, Massimo [0000-0002-9659-9470], Tzanetakis, Ioannis E. [0000-0002-5970-1763], Vaira, Anna Maria [0000-0003-2526-4419], Van den Hoogen, Bernadette [0000-0003-1996-8559], Vanmechelen, Bert [0000-0002-8350-4356], Verbeek, Martin [0000-0002-8973-3803], Von Bargen, Susanne [0000-0001-8321-1572], Wada, Jiro [0000-0001-9846-0846], Wahl, Victoria [0000-0002-6588-4308], Walker, Peter J. [0000-0003-1851-642X], Waltzek, Thomas B. [0000-0001-6383-5978], Whitfield, Anna E. [0000-0002-3538-015X], Wolf, Yuri I. [0000-0002-0247-8708], Xylogianni, Evanthia [0009-0001-8768-0939], Yanagisawa, Hironobu [0000-0002-6729-466X], Ye, Gongyin [0000-0003-4937-8867], Yuan, Zhiming [0000-0002-3234-9616], Zerbini, F. Murilo [0000-0001-8617-0200], Okland, Arnfinn Lodden [0000-0003-3062-4386], Kuhn, Jens H., Abe, Junya, Adkins, Scott, Alkhovsky, Sergey V., Avsic-Zupanc, Tatjana, Ayllón, María A., Bahl, Justin, Balkema-Buschmann, A., Ballinger, Matthew J., Kumar Baranwal, Virendra, Beer, Martin, Bejerman, Nicolas, Bergeron, Éric, Biedenkopf, Nadine, Blair, Carol D., Blasdell, Kim R., Blouin, Arnaud G., Bradfute, Steven B., Briese, Thomas, Brown, Paul A., Buchholz, Ursula J., Buchmeier, Michael J., Bukreyev, Alexander, Burt, Felicity, Büttner, Carmen, Calisher, Charles H., Cao, Mengji, Casas, Inmaculada, Chandran, Kartik, Charrel, Rémi N., Chaturvedi, Krishna Kumar, Chooi, Kar Mun, Crane, Anya, Dal Bó, Elena, de la Torre, J. C., de Souza, William Marciel, De Swart, Rik L., Debat, Humberto, Dheilly, Nolwenn M., Di Paola, Nicholas, Di Serio, Francesco, Dietzgen, Ralf G., Digiaro, Michele, Drexler, J. Felix, Duprex, W. Paul, Dürrwald, Ralf, Easton, Andrew J., Elbeaino, Toufic, Ergünay, Koray, Feng, Guozhong, Firth, Andrew E., Fooks, Anthony R., Formenty, Pierre B.H., Freitas-Astúa, Juliana, Gago-Zachert, Selma, García, María Laura, García-Sastre, Adolfo, Garrison, Aura R., Gaskin, Thomas R., Gong, Wenjie, Gonzalez, Jean-Paul J., Gouy de Bellocq, Joelle, Griffiths, Anthony, Groschup, M. H., Günther, Ines, Günther, Stephan, Hammond, John, Hasegawa, Yusuke, Hayashi, Kazusa, Hepojoki, Jussi, Higgins, Colleen M., Hongo, Seiji, Horie, Masayuki, Hughes, Holly R., Hume, Adam J., Hyndman, Timothy, Ikeda, Kenichi, Jiāng, Dàohóng, Jonson, Gilda B., Junglen, Sandra, Klempa, B., Klingström, Jonas, Kondō, Hideki, Koonin, Eugene V., Krupovic, Mart, Kubota, Kenji, Kurath, Gael, Laenen, Lies, Lambert, Amy J., Li, Jianrong, Li, Jun-Min, Liu, Ran, Lukashevich, Igor S., MacDiarmid, Robin M, Maes, Piet, Marklewitz, Marco, Marshall, Sergio H., Marzano, Shin-Yi L., McCauley, John W., Mirazimi, Ali, Mühlberger, Elke, Nabeshima, Tomoyuki, Naidu, Rayapati, Natsuaki, Tomohide, Navarro, Beatriz, Navarro, José A., Neriya, Yutaro, Netesov, Sergey V., Neumann, Gabriele, Nowotny, N., Nunes, Márcio R.T., Ochoa-Corona, Francisco M., Okada, Tomoyuki, Palacios, Gustavo, Pallás, Vicente, Papa, Anna, Paraskevopoulou, Sofia, Parrish, Colin R., Pauvolid-Corrêa, Alex, Pawęska, Janusz T., Pérez, Daniel R., Pfaff, Florian, Plemper, Richard K., Postler, Thomas S., Rabbidge, Lee O., Radoshitzky, Sheli R., Ramos-González, Pedro L., Rehanek, Marius, Resende, Renato O., Reyes, Carina A., Rodrigues, Thaís C.S., Romanowski, Víctor, Rubbenstroth, Dennis, Rubino, Luisa, Runstadler, Jonathan A., Sabanadzovic, Sead, Sadiq, Sabrina, Salvato, Maria S., Sasaya, Takahide, Schwemmle, Martin, Sharpe, Stephen R., Shi, Mang, Shimomoto, Yoshifumi, Kavi Sidharthan, Venkidusamy, Sironi, Manuela, Smither, Sophie, Song, Jin-Won, Spann, Kirsten, Spengler, Jessica R., Stenglein, Mark D., Takada, Ayato, Takeyama, Sawana, Tatara, Akio, Tesh, Robert B., Thornburg, Natalie J., Tian, Xin, Tischler, Nicole D., Tomitaka, Yasuhiro, Tomonaga, Keizō, Tordo, Noël, Tu, Changchun, Turina, Massimo, Tzanetakis, Ioannis E., Vaira, Anna Maria, Van den Hoogen, Bernadette, Vanmechelen, Bert, Vasilakis, Nikos, Verbeek, Martin, Von Bargen, Susanne, Wada, Jiro, Wahl, Victoria, Walker, Peter J., Waltzek, Thomas B., Whitfield, Anna E., Wolf, Yuri I., Xia, Han, Xylogianni, Evanthia, Yanagisawa, Hironobu, Yano, Kazutaka, Ye, Gongyin, Yuan, Zhiming, Zerbini, F. Murilo, Zhang, Guilin, Zhang, Song, Zhang, Yong-Zhen, Zhao, Lu, and Okland, Arnfinn Lodden

Abstract

In April 2023, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. The phylum was expanded by one new family, 14 new genera, and 140 new species. Two genera and 538 species were renamed. One species was moved, and four were abolished. This article presents the updated taxonomy of Negarnaviricota as now accepted by the ICTV.

Published
2023

23. Tunable and reversible drug control of protein production via a self-excising degron

Author

Chung, Hokyung K, Jacobs, Conor L, Huo, Yunwen, Yang, Jin, Krumm, Stefanie A, Plemper, Richard K, Tsien, Roger Y, and Lin, Michael Z

Subjects
Biochemistry and Cell Biology, Biological Sciences, Emerging Infectious Diseases, Hepatitis, Hepatitis - C, Infectious Diseases, Liver Disease, Digestive Diseases, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Good Health and Well Being, Amino Acid Sequence, Animals, Bacterial Proteins, Binding Sites, Carrier Proteins, Chlorocebus aethiops, Gene Expression Regulation, HEK293 Cells, HeLa Cells, Hepacivirus, Humans, Intracellular Signaling Peptides and Proteins, Isoquinolines, Luminescent Proteins, Molecular Sequence Data, Neurons, Primary Cell Culture, Protease Inhibitors, Protein Binding, Proteolysis, Rats, Rats, Sprague-Dawley, Recombinant Fusion Proteins, Sulfonamides, Vero Cells, Viral Nonstructural Proteins, Hela Cells, Medicinal and Biomolecular Chemistry, Biochemistry & Molecular Biology, Biochemistry and cell biology, Medicinal and biomolecular chemistry
Abstract

An effective method for direct chemical control over the production of specific proteins would be widely useful. We describe small molecule-assisted shutoff (SMASh), a technique in which proteins are fused to a degron that removes itself in the absence of drug, resulting in the production of an untagged protein. Clinically tested HCV protease inhibitors can then block degron removal, inducing rapid degradation of subsequently synthesized copies of the protein. SMASh allows reversible and dose-dependent shutoff of various proteins in multiple mammalian cell types and in yeast. We also used SMASh to confer drug responsiveness onto an RNA virus for which no licensed inhibitors exist. As SMASh does not require the permanent fusion of a large domain, it should be useful when control over protein production with minimal structural modification is desired. Furthermore, as SMASh involves only a single genetic modification and does not rely on modulating protein-protein interactions, it should be easy to generalize to multiple biological contexts.

Published
2015

28. Design and Optimization of Novel Competitive, Non-peptidic, SARS-CoV-2 Mpro Inhibitors

Author

Jacobs, Leon, primary, van der Westhuyzen, Aletta, additional, Pribut, Nicole, additional, Dentmon, Zackery W., additional, Cui, Dan, additional, D’Erasmo, Michael P., additional, Bartsch, Perry W., additional, Liu, Ken, additional, Cox, Robert M., additional, Greenlund, Sujay F., additional, Plemper, Richard K., additional, Mitchell, Deborah, additional, Marlow, Joshua, additional, Andrews, Meghan K., additional, Krueger, Rebecca E., additional, Sticher, Zachary M., additional, Kolykhalov, Alexander A., additional, Natchus, Michael G., additional, Zhou, Bin, additional, Pelly, Stephen C., additional, and Liotta, Dennis C., additional

Published
2023
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30. Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets

Author

Plemper, Richard K., primary, Cox, Robert, additional, Wolf, Josef D, additional, Lieberman, Nicole A.P., additional, Lieber, Carolin M, additional, Kang, Hae-Ji, additional, Sticher, Zachary M, additional, Yoon, Jeong-Joong, additional, Andrews, Meghan K, additional, Govindarajan, Mugunthan, additional, Krueger, Rebecca E, additional, Sobolik, Elizabeth B, additional, Natchus, Michael G, additional, Gewirtz, Andrew, additional, deSwart, Rik, additional, Kolykhalov, Alexander, additional, Hekmatyar, Khan, additional, Sakamoto, Kaori, additional, and Greninger, Alexander L., additional

Published
2023
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31. Annual (2023) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota)

Author

Kuhn, Jens H., primary, Abe, Junya, additional, Adkins, Scott, additional, Alkhovsky, Sergey V., additional, Avšič-Županc, Tatjana, additional, Ayllón, María A., additional, Bahl, Justin, additional, Balkema-Buschmann, Anne, additional, Ballinger, Matthew J., additional, Kumar Baranwal, Virendra, additional, Beer, Martin, additional, Bejerman, Nicolas, additional, Bergeron, Éric, additional, Biedenkopf, Nadine, additional, Blair, Carol D., additional, Blasdell, Kim R., additional, Blouin, Arnaud G., additional, Bradfute, Steven B., additional, Briese, Thomas, additional, Brown, Paul A., additional, Buchholz, Ursula J., additional, Buchmeier, Michael J., additional, Bukreyev, Alexander, additional, Burt, Felicity, additional, Büttner, Carmen, additional, Calisher, Charles H., additional, Cao, Mengji, additional, Casas, Inmaculada, additional, Chandran, Kartik, additional, Charrel, Rémi N., additional, Kumar Chaturvedi, Krishna, additional, Chooi, Kar Mun, additional, Crane, Anya, additional, Dal Bó, Elena, additional, Carlos de la Torre, Juan, additional, de Souza, William M., additional, de Swart, Rik L., additional, Debat, Humberto, additional, Dheilly, Nolwenn M., additional, Di Paola, Nicholas, additional, Di Serio, Francesco, additional, Dietzgen, Ralf G., additional, Digiaro, Michele, additional, Drexler, J. Felix, additional, Duprex, W. Paul, additional, Dürrwald, Ralf, additional, Easton, Andrew J., additional, Elbeaino, Toufic, additional, Ergünay, Koray, additional, Feng, Guozhong, additional, Firth, Andrew E., additional, Fooks, Anthony R., additional, Formenty, Pierre B. H., additional, Freitas-Astúa, Juliana, additional, Gago-Zachert, Selma, additional, Laura García, María, additional, García-Sastre, Adolfo, additional, Garrison, Aura R., additional, Gaskin, Thomas R., additional, Gong, Wenjie, additional, Gonzalez, Jean-Paul J., additional, de Bellocq, JoëlleGoüy, additional, Griffiths, Anthony, additional, Groschup, Martin H., additional, Günther, Ines, additional, Günther, Stephan, additional, Hammond, John, additional, Hasegawa, Yusuke, additional, Hayashi, Kazusa, additional, Hepojoki, Jussi, additional, Higgins, Colleen M., additional, Hongō, Seiji, additional, Horie, Masayuki, additional, Hughes, Holly R., additional, Hume, Adam J., additional, Hyndman, Timothy H., additional, Ikeda, Kenichi, additional, Jiāng, Dàohóng, additional, Jonson, Gilda B., additional, Junglen, Sandra, additional, Klempa, Boris, additional, Klingström, Jonas, additional, Kondō, Hideki, additional, Koonin, Eugene V., additional, Krupovic, Mart, additional, Kubota, Kenji, additional, Kurath, Gael, additional, Laenen, Lies, additional, Lambert, Amy J., additional, Lǐ, Jiànróng, additional, Li, Jun-Min, additional, Liu, Ran, additional, Lukashevich, Igor S., additional, MacDiarmid, Robin M., additional, Maes, Piet, additional, Marklewitz, Marco, additional, Marshall, Sergio H., additional, Marzano, Shin-Yi L., additional, McCauley, John W., additional, Mirazimi, Ali, additional, Mühlberger, Elke, additional, Nabeshima, Tomoyuki, additional, Naidu, Rayapati, additional, Natsuaki, Tomohide, additional, Navarro, Beatriz, additional, Navarro, José A., additional, Neriya, Yutaro, additional, Netesov, Sergey V., additional, Neumann, Gabriele, additional, Nowotny, Norbert, additional, Nunes, Márcio R. T., additional, Ochoa-Corona, Francisco M., additional, Okada, Tomoyuki, additional, Palacios, Gustavo, additional, Pallás, Vicente, additional, Papa, Anna, additional, Paraskevopoulou, Sofia, additional, Parrish, Colin R., additional, Pauvolid-Corrêa, Alex, additional, Pawęska, Janusz T., additional, Pérez, Daniel R., additional, Pfaff, Florian, additional, Plemper, Richard K., additional, Postler, Thomas S., additional, Rabbidge, Lee O., additional, Radoshitzky, Sheli R., additional, Ramos-González, Pedro L., additional, Rehanek, Marius, additional, Resende, Renato O., additional, Reyes, Carina A., additional, Rodrigues, Thaís C. S., additional, Romanowski, Víctor, additional, Rubbenstroth, Dennis, additional, Rubino, Luisa, additional, Runstadler, Jonathan A., additional, Sabanadzovic, Sead, additional, Sadiq, Sabrina, additional, Salvato, Maria S., additional, Sasaya, Takahide, additional, Schwemmle, Martin, additional, Sharpe, Stephen R., additional, Shi, Mang, additional, Shimomoto, Yoshifumi, additional, Kavi Sidharthan, Venkidusamy, additional, Sironi, Manuela, additional, Smither, Sophie, additional, Song, Jin-Won, additional, Spann, Kirsten M., additional, Spengler, Jessica R., additional, Stenglein, Mark D., additional, Takada, Ayato, additional, Takeyama, Sawana, additional, Tatara, Akio, additional, Tesh, Robert B., additional, Thornburg, Natalie J., additional, Tian, Xin, additional, Tischler, Nicole D., additional, Tomitaka, Yasuhiro, additional, Tomonaga, Keizō, additional, Tordo, Noël, additional, Tu, Changchun, additional, Turina, Massimo, additional, Tzanetakis, Ioannis E., additional, Maria Vaira, Anna, additional, van den Hoogen, Bernadette, additional, Vanmechelen, Bert, additional, Vasilakis, Nikos, additional, Verbeek, Martin, additional, von Bargen, Susanne, additional, Wada, Jiro, additional, Wahl, Victoria, additional, Walker, Peter J., additional, Waltzek, Thomas B., additional, Whitfield, Anna E., additional, Wolf, Yuri I., additional, Xia, Han, additional, Xylogianni, Evanthia, additional, Yanagisawa, Hironobu, additional, Yano, Kazutaka, additional, Ye, Gongyin, additional, Yuan, Zhiming, additional, Zerbini, F. Murilo, additional, Zhang, Guilin, additional, Zhang, Song, additional, Zhang, Yong-Zhen, additional, Zhao, Lu, additional, and Økland, Arnfinn Lodden, additional

Published
2023
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32. A Target Site for Template-Based Design of Measles Virus Entry Inhibitors

Author

Plemper, Richard K., Erlandson, Karl J., Lakdawala, Ami S., Sun, Aiming, Prussia, Andrew, Boonsombat, Jutatip, Aki-Sener, Esin, Yalcin, Ismail, Yildiz, Ilkay, Temiz-Arpaci, Ozlem, Tekiner, Betul, Liotta, Dennis C., Snyder, James P., Compans, Richard W., and Palese, Peter

Published
2004

33. Immunization with Recombinant Accessory Protein-Deficient SARS-CoV-2 Protects against Lethal Challenge and Viral Transmission

Author

Ye, Chengjin, primary, Park, Jun-Gyu, additional, Chiem, Kevin, additional, Dravid, Piyush, additional, Allué-Guardia, Anna, additional, Garcia-Vilanova, Andreu, additional, Pino Tamayo, Paula, additional, Shivanna, Vinay, additional, Kapoor, Amit, additional, Walter, Mark R., additional, Kobie, James J., additional, Plemper, Richard K., additional, Torrelles, Jordi B., additional, and Martinez-Sobrido, Luis, additional

Published
2023
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34. Metagenomics-enabled reverse-genetics assembly and characterization of myotis bat morbillivirus

Author

Ikegame, Satoshi, primary, Carmichael, Jillian C., additional, Wells, Heather, additional, Furler O’Brien, Robert L., additional, Acklin, Joshua A., additional, Chiu, Hsin-Ping, additional, Oguntuyo, Kasopefoluwa Y., additional, Cox, Robert M., additional, Patel, Aum R., additional, Kowdle, Shreyas, additional, Stevens, Christian S., additional, Eckley, Miles, additional, Zhan, Shijun, additional, Lim, Jean K., additional, Veit, Ethan C., additional, Evans, Matthew J., additional, Hashiguchi, Takao, additional, Durigon, Edison, additional, Schountz, Tony, additional, Epstein, Jonathan H., additional, Plemper, Richard K., additional, Daszak, Peter, additional, Anthony, Simon J., additional, and Lee, Benhur, additional

Published
2023
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36. 4’-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses

Author

Lieber, Carolin M., primary, Aggarwal, Megha, additional, Yoon, Jeong-Joong, additional, Cox, Robert M., additional, Kang, Hae-Ji, additional, Sourimant, Julien, additional, Toots, Mart, additional, Johnson, Scott K., additional, Jones, Cheryl A., additional, Sticher, Zachary M., additional, Kolykhalov, Alexander A., additional, Saindane, Manohar T., additional, Tompkins, Stephen M., additional, Planz, Oliver, additional, Painter, George R., additional, Natchus, Michael G., additional, Sakamoto, Kaori, additional, and Plemper, Richard K., additional

Published
2023
Full Text
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37. Annual (2023) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota)

Author

Kuhn, Jens H., Abe, Junya, Adkins, Scott, Alkhovsky, Sergey V., Avšič-Županc, Tatjana, Ayllón, María A., Bahl, Justin, Balkema-Buschmann, Anne, Ballinger, Matthew J., Baranwal, Virendra Kumar, Beer, Martin, Bejerman, Nicolas, Bergeron, Éric, Biedenkopf, Nadine, Blair, Carol D., Blasdell, Kim R., Blouin, Arnaud G., Bradfute, Steven B., Briese, Thomas, Brown, Paul A., Buchholz, Ursula J., Buchmeier, Michael J., Bukreyev, Alexander, Burt, Felicity, Büttner, Carmen, Calisher, Charles H., Cao, Mengji, Casas, Inmaculada, Chandran, Kartik, Charrel, Rémi N., Chaturvedi, Krishna Kumar, Chooi, Kar Mun, Crane, Anya, Bó, Elena Dal, de la Torre, Juan Carlos, de Souza, William M., de Swart, Rik L., Debat, Humberto, Dheilly, Nolwenn M., Di Paola, Nicholas, Di Serio, Francesco, Dietzgen, Ralf G., Digiaro, Michele, Drexler, J.F., Duprex, W.P., Dürrwald, Ralf, Easton, Andrew J., Elbeaino, Toufic, Ergünay, Koray, Feng, Guozhong, Firth, Andrew E., Fooks, Anthony R., Formenty, Pierre B.H., Freitas-Astúa, Juliana, Gago-Zachert, Selma, García, María Laura, García-Sastre, Adolfo, Garrison, Aura R., Gaskin, Thomas R., Gong, Wenjie, Gonzalez, Jean Paul J., de Bellocq, Joëlle Goüy, Griffiths, Anthony, Groschup, Martin H., Günther, Ines, Günther, Stephan, Hammond, John, Hasegawa, Yusuke, Hayashi, Kazusa, Hepojoki, Jussi, Higgins, Colleen M., Hongō, Seiji, Horie, Masayuki, Hughes, Holly R., Hume, Adam J., Hyndman, Timothy H., Ikeda, Kenichi, Jiāng, Dàohóng, Jonson, Gilda B., Junglen, Sandra, Klempa, Boris, Klingström, Jonas, Kondō, Hideki, Koonin, Eugene V., Krupovic, Mart, Kubota, Kenji, Kurath, Gael, Laenen, Lies, Lambert, Amy J., Lǐ, Jiànróng, Li, Jun Min, Liu, Ran, Lukashevich, Igor S., MacDiarmid, Robin M., Maes, Piet, Marklewitz, Marco, Marshall, Sergio H., Marzano, Shin Yi L., McCauley, John W., Mirazimi, Ali, Mühlberger, Elke, Nabeshima, Tomoyuki, Naidu, Rayapati, Natsuaki, Tomohide, Navarro, Beatriz, Navarro, José A., Neriya, Yutaro, Netesov, Sergey V., Neumann, Gabriele, Nowotny, Norbert, Nunes, Márcio R.T., Ochoa-Corona, Francisco M., Okada, Tomoyuki, Palacios, Gustavo, Pallás, Vicente, Papa, Anna, Paraskevopoulou, Sofia, Parrish, Colin R., Pauvolid-Corrêa, Alex, Pawęska, Janusz T., Pérez, Daniel R., Pfaff, Florian, Plemper, Richard K., Postler, Thomas S., Rabbidge, Lee O., Radoshitzky, Sheli R., Ramos-González, Pedro L., Rehanek, Marius, Resende, Renato O., Reyes, Carina A., Rodrigues, Thaís C.S., Romanowski, Víctor, Rubbenstroth, Dennis, Rubino, Luisa, Runstadler, Jonathan A., Sabanadzovic, Sead, Sadiq, Sabrina, Salvato, Maria S., Sasaya, Takahide, Schwemmle, Martin, Sharpe, Stephen R., Shi, Mang, Shimomoto, Yoshifumi, Sidharthan, Venkidusamy Kavi, Sironi, Manuela, Smither, Sophie, Song, Jin Won, Spann, Kirsten M., Spengler, Jessica R., Stenglein, Mark D., Takada, Ayato, Takeyama, Sawana, Tatara, Akio, Tesh, Robert B., Thornburg, Natalie J., Tian, Xin, Tischler, Nicole D., Tomitaka, Yasuhiro, Tomonaga, Keizō, Tordo, Noël, Tu, Changchun, Turina, Massimo, Tzanetakis, Ioannis E., Vaira, Anna Maria, van den Hoogen, Bernadette, Vanmechelen, Bert, Vasilakis, Nikos, Verbeek, Martin, von Bargen, Susanne, Wada, Jiro, Wahl, Victoria, Walker, Peter J., Waltzek, Thomas B., Whitfield, Anna E., Wolf, Yuri I., Xia, Han, Xylogianni, Evanthia, Yanagisawa, Hironobu, Yano, Kazutaka, Ye, Gongyin, Yuan, Zhiming, Zerbini, F.M., Zhang, Guilin, Zhang, Song, Zhang, Yong Zhen, Zhao, Lu, Økland, Arnfinn Lodden, Kuhn, Jens H., Abe, Junya, Adkins, Scott, Alkhovsky, Sergey V., Avšič-Županc, Tatjana, Ayllón, María A., Bahl, Justin, Balkema-Buschmann, Anne, Ballinger, Matthew J., Baranwal, Virendra Kumar, Beer, Martin, Bejerman, Nicolas, Bergeron, Éric, Biedenkopf, Nadine, Blair, Carol D., Blasdell, Kim R., Blouin, Arnaud G., Bradfute, Steven B., Briese, Thomas, Brown, Paul A., Buchholz, Ursula J., Buchmeier, Michael J., Bukreyev, Alexander, Burt, Felicity, Büttner, Carmen, Calisher, Charles H., Cao, Mengji, Casas, Inmaculada, Chandran, Kartik, Charrel, Rémi N., Chaturvedi, Krishna Kumar, Chooi, Kar Mun, Crane, Anya, Bó, Elena Dal, de la Torre, Juan Carlos, de Souza, William M., de Swart, Rik L., Debat, Humberto, Dheilly, Nolwenn M., Di Paola, Nicholas, Di Serio, Francesco, Dietzgen, Ralf G., Digiaro, Michele, Drexler, J.F., Duprex, W.P., Dürrwald, Ralf, Easton, Andrew J., Elbeaino, Toufic, Ergünay, Koray, Feng, Guozhong, Firth, Andrew E., Fooks, Anthony R., Formenty, Pierre B.H., Freitas-Astúa, Juliana, Gago-Zachert, Selma, García, María Laura, García-Sastre, Adolfo, Garrison, Aura R., Gaskin, Thomas R., Gong, Wenjie, Gonzalez, Jean Paul J., de Bellocq, Joëlle Goüy, Griffiths, Anthony, Groschup, Martin H., Günther, Ines, Günther, Stephan, Hammond, John, Hasegawa, Yusuke, Hayashi, Kazusa, Hepojoki, Jussi, Higgins, Colleen M., Hongō, Seiji, Horie, Masayuki, Hughes, Holly R., Hume, Adam J., Hyndman, Timothy H., Ikeda, Kenichi, Jiāng, Dàohóng, Jonson, Gilda B., Junglen, Sandra, Klempa, Boris, Klingström, Jonas, Kondō, Hideki, Koonin, Eugene V., Krupovic, Mart, Kubota, Kenji, Kurath, Gael, Laenen, Lies, Lambert, Amy J., Lǐ, Jiànróng, Li, Jun Min, Liu, Ran, Lukashevich, Igor S., MacDiarmid, Robin M., Maes, Piet, Marklewitz, Marco, Marshall, Sergio H., Marzano, Shin Yi L., McCauley, John W., Mirazimi, Ali, Mühlberger, Elke, Nabeshima, Tomoyuki, Naidu, Rayapati, Natsuaki, Tomohide, Navarro, Beatriz, Navarro, José A., Neriya, Yutaro, Netesov, Sergey V., Neumann, Gabriele, Nowotny, Norbert, Nunes, Márcio R.T., Ochoa-Corona, Francisco M., Okada, Tomoyuki, Palacios, Gustavo, Pallás, Vicente, Papa, Anna, Paraskevopoulou, Sofia, Parrish, Colin R., Pauvolid-Corrêa, Alex, Pawęska, Janusz T., Pérez, Daniel R., Pfaff, Florian, Plemper, Richard K., Postler, Thomas S., Rabbidge, Lee O., Radoshitzky, Sheli R., Ramos-González, Pedro L., Rehanek, Marius, Resende, Renato O., Reyes, Carina A., Rodrigues, Thaís C.S., Romanowski, Víctor, Rubbenstroth, Dennis, Rubino, Luisa, Runstadler, Jonathan A., Sabanadzovic, Sead, Sadiq, Sabrina, Salvato, Maria S., Sasaya, Takahide, Schwemmle, Martin, Sharpe, Stephen R., Shi, Mang, Shimomoto, Yoshifumi, Sidharthan, Venkidusamy Kavi, Sironi, Manuela, Smither, Sophie, Song, Jin Won, Spann, Kirsten M., Spengler, Jessica R., Stenglein, Mark D., Takada, Ayato, Takeyama, Sawana, Tatara, Akio, Tesh, Robert B., Thornburg, Natalie J., Tian, Xin, Tischler, Nicole D., Tomitaka, Yasuhiro, Tomonaga, Keizō, Tordo, Noël, Tu, Changchun, Turina, Massimo, Tzanetakis, Ioannis E., Vaira, Anna Maria, van den Hoogen, Bernadette, Vanmechelen, Bert, Vasilakis, Nikos, Verbeek, Martin, von Bargen, Susanne, Wada, Jiro, Wahl, Victoria, Walker, Peter J., Waltzek, Thomas B., Whitfield, Anna E., Wolf, Yuri I., Xia, Han, Xylogianni, Evanthia, Yanagisawa, Hironobu, Yano, Kazutaka, Ye, Gongyin, Yuan, Zhiming, Zerbini, F.M., Zhang, Guilin, Zhang, Song, Zhang, Yong Zhen, Zhao, Lu, and Økland, Arnfinn Lodden

Abstract

In April 2023, following the annual International Committee on Taxonomy of Viruses (ICTV) ratification vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. The phylum was expanded by one new family, 14 new genera, and 140 new species. Two genera and 538 species were renamed. One species was moved, and four were abolished.

Published
2023

38. Design and Optimization of Novel Competitive, Non-peptidic, SARS-CoV‑2 Mpro Inhibitors.

Author

Jacobs, Leon, van der Westhuyzen, Aletta, Pribut, Nicole, Dentmon, Zackery W., Cui, Dan, D'Erasmo, Michael P., Bartsch, Perry W., Liu, Ken, Cox, Robert M., Greenlund, Sujay F., Plemper, Richard K., Mitchell, Deborah, Marlow, Joshua, Andrews, Meghan K., Krueger, Rebecca E., Sticher, Zachary M., Kolykhalov, Alexander A., Natchus, Michael G., Zhou, Bin, and Pelly, Stephen C.

Published
2023
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39. Paxlovid-like nirmatrelvir/ritonavir fails to block SARS-CoV-2 transmission in ferrets

Author

Cox, Robert M, primary, Lieber, Carolin M, additional, Wolf, Josef D, additional, Karimi, Amirhossein, additional, Lieberman, Nicole A P, additional, Sticher, Zachary M, additional, Roychoudhury, Pavitra, additional, Andrews, Meghan K, additional, Krueger, Rebecca E, additional, Natchus, Michael G, additional, Painter, George R, additional, Kolykhalov, Alexander A, additional, Greninger, Alexander L, additional, and Plemper, Richard K, additional

Published
2022
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40. 4’-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses

Author

Lieber, Carolin M, primary, Aggarwal, Megha, additional, Yoon, Jeong-Joong, additional, Cox, Robert M, additional, Sourimant, Julien, additional, Toots, Mart, additional, Kang, Hae-Ji, additional, Johnson, Scott K, additional, Jones, Cheryl A, additional, Sticher, Zachary M, additional, Kolykhalov, Alexander A, additional, Saindane, Manohar T, additional, Tompkins, Stephen M, additional, Planz, Oliver, additional, Painter, George R, additional, Natchus, Michael G, additional, Sakamoto, Kaori, additional, and Plemper, Richard K, additional

Published
2022
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42. Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection

Author

Brown, Julia A., primary, Sanidad, Katherine Z., additional, Lucotti, Serena, additional, Lieber, Carolin M., additional, Cox, Robert M., additional, Ananthanarayanan, Aparna, additional, Basu, Srijani, additional, Chen, Justin, additional, Shan, Mengrou, additional, Amir, Mohammed, additional, Schmidt, Fabian, additional, Weisblum, Yiska, additional, Cioffi, Michele, additional, Li, Tingting, additional, Rowdo, Florencia Madorsky, additional, Martin, M. Laura, additional, Guo, Chun-Jun, additional, Lyssiotis, Costas A., additional, Layden, Brian T., additional, Dannenberg, Andrew J., additional, Bieniasz, Paul D., additional, Lee, Benhur, additional, Inohara, Naohiro, additional, Matei, Irina, additional, Plemper, Richard K., additional, and Zeng, Melody Y., additional

Published
2022
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44. Orally efficacious lead of the AVG inhibitor series targeting a dynamic interface in the respiratory syncytial virus polymerase

Author

Sourimant, Julien, primary, Lieber, Carolin M., additional, Yoon, Jeong-Joong, additional, Toots, Mart, additional, Govindarajan, Mugunthan, additional, Udumula, Venkata, additional, Sakamoto, Kaori, additional, Natchus, Michael G., additional, Patti, Joseph, additional, Vernachio, John, additional, and Plemper, Richard K., additional

Published
2022
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45. Protein Degradation in Human Disease

Author

Plemper, Richard K., Hammond, Anthea L., Müller, W. E. G., editor, Jeanteur, Ph., editor, Kostovic, I., editor, Kuchino, Y., editor, Macieira-Coelho, A., editor, Rhoads, R. E., editor, and Reboud-Ravaux, Michèle, editor

Published
2002
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47. Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice

Author

Wong, Ting Y., primary, Horspool, Alexander M., additional, Russ, Brynnan P., additional, Ye, Chengjin, additional, Lee, Katherine S., additional, Winters, Michael T., additional, Bevere, Justin R., additional, Miller, Olivia A., additional, Rader, Nathaniel A., additional, Cooper, Melissa, additional, Kieffer, Theodore, additional, Sourimant, Julien, additional, Greninger, Alexander L., additional, Plemper, Richard K., additional, Denvir, James, additional, Cyphert, Holly A., additional, Barbier, Mariette, additional, Torrelles, Jordi B., additional, Martinez, Ivan, additional, Martinez-Sobrido, Luis, additional, and Damron, F. Heath, additional

Published
2022
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48. Immunization with recombinant accessory protein-deficient SARS-CoV-2 protects against lethal challenge and viral transmission

Author

Ye, Chengjin, primary, Park, Jun-Gyu, additional, Chiem, Kevin, additional, Dravid, Piyush, additional, Allue Guardia, Anna, additional, Garcia-Vilanova, Andreu, additional, kapoor, Amit, additional, Walter, Mark R, additional, Kobie, James, additional, Plemper, Richard K., additional, Torrelles, Jordi B, additional, and Martinez-Sobrido, Luis, additional

Published
2022
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49. SARS-CoV-2 variant of concern type and biological sex affect efficacy of molnupiravir in dwarf hamster model of severe COVID-19

Author

Lieber, Carolin M., primary, Cox, Robert M, additional, Sourimant, Julien, additional, Wolf, Josef D., additional, Juergens, Kate, additional, Phung, Quynh, additional, Saindane, Manohar T, additional, Natchus, Michael G, additional, Painter, George R, additional, Sakamoto, Kaori, additional, Greninger, Alexander L., additional, and Plemper, Richard K, additional

Published
2022
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50. 4′-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication

Author

Sourimant, Julien, primary, Lieber, Carolin M., additional, Aggarwal, Megha, additional, Cox, Robert M., additional, Wolf, Josef D., additional, Yoon, Jeong-Joong, additional, Toots, Mart, additional, Ye, Chengin, additional, Sticher, Zachary, additional, Kolykhalov, Alexander A., additional, Martinez-Sobrido, Luis, additional, Bluemling, Gregory R., additional, Natchus, Michael G., additional, Painter, George R., additional, and Plemper, Richard K., additional

Published
2022
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