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1,521 results on '"Platanias, Leonidas C."'

1. Polycomb group protein Mel18 inhibits hematopoietic stem cell self-renewal through repressing the transcription of self-renewal and proliferation genes

Author

Cai, Wenjie, Liu, Xicheng, Barajas, Sergio, Xiao, Shiyu, Vemula, Sasidhar, Chen, Hongxia, Yang, Yuxia, Bochers, Christopher, Henley, Danielle, Liu, Sheng, Jia, Yuzhi, Hong, Michelle, Mays, Tiffany M., Capitano, Maegan L., Liu, Huiping, Ji, Peng, Gao, Zhonghua, Pasini, Diego, Wan, Jun, Yue, Feng, Platanias, Leonidas C., Xi, Rongwen, Chen, Sisi, and Liu, Yan

Published
2024
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2. B cell-based therapy produces antibodies that inhibit glioblastoma growth

Author

Wang, Si, Castro, Brandyn A., Katz, Joshua L., Arrieta, Victor, Najem, Hinda, Vazquez-Cervantes, Gustavo I., Wan, Hanxiao, Olson, Ian E., Hou, David, Dapash, Mark, Billingham, Leah K., Chia, Tzu- yi, Wei, Chao, Rashidi, Aida, Platanias, Leonidas C., McCortney, Kathleen, Horbinski, Craig M., Stupp, Roger, Zhang, Peng, Ahmed, Atique U., Sonabend, Adam M., Heimberger, Amy B., Lesniak, Maciej S., Riviere-Cazaux, Cecile, Burns, Terry, Miska, Jason, Fischietti, Mariafausta, and Lee-Chang, Catalina

Subjects
Medical research, Medicine, Experimental, Viral antibodies -- Health aspects, Immunotherapy -- Physiological aspects, B cells -- Health aspects, Glioblastoma multiforme -- Care and treatment -- Physiological aspects, Antibodies -- Health aspects
Abstract

Glioblastoma (GBM) is a highly aggressive and malignant brain tumor with limited therapeutic options and a poor prognosis. Despite current treatments, the invasive nature of GBM often leads to recurrence. A promising alternative strategy is to harness the potential of the immune system against tumor cells. Our previous data showed that the [B.sub.Vax] (B cell- based vaccine) can induce therapeutic responses in preclinical models of GBM. In this study, we aimed to characterize the antigenic reactivity of [B.sub.Vax]-derived Abs and evaluate their therapeutic potential. We performed immunoproteomics and functional assays in murine models and samples from patients with GBM. Our investigations revealed that [B.sub.Vax] distributed throughout the GBM tumor microenvironment and then differentiated into Ab-producing plasmablasts. Proteomics analyses indicated that the Abs produced by [B.sub.Vax] had unique reactivity, predominantly targeting factors associated with cell motility and the extracellular matrix. Crucially, these Abs inhibited critical processes such as GBM cell migration and invasion. These findings provide valuable insights into the therapeutic potential of [B.sub.Vax]-derived Abs for patients with GBM, pointing toward a novel direction for GBM immunotherapy., Introduction Glioblastoma (GBM) is an aggressive and malignant brain tumor that arises from glial cells (1). GBM is one of the most common and deadly forms of brain cancer in [...]

Published
2024
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3. STING agonist 8803 reprograms the immune microenvironment and increases survival in preclinical models of glioblastoma

Author

Najem, Hinda, Lea, Spencer T., Tripathi, Shashwat, Hurley, Lisa, Chen, Chao- Hsien, William, Ivana, Sooreshjani, Moloud, Bowie, Michelle, Hartley, Genevieve, Dussold, Corey, Pacheco, Sebastian, Dmello, Crismita, Lee-Chang, Catalina, McCortney, Kathleen, Steffens, Alicia, Walshon, Jordain, Martina Ot, Wei, Jun, Marisetty, Anantha, Balyasnikova, Irina, Stupp, Roger, Lukas, Rimas V., Hu, Jian, James, Charles David, Horbinski, Craig M., Lesniak, Maciej S., Ashley, David M., Priebe, Waldemar, Platanias, Leonidas C., Curran, Michael A., and Heimberger, Amy B.

Subjects
Oncology, Experimental, Agonists (Biochemistry) -- Research, Gene expression -- Research, Immune response -- Genetic aspects -- Health aspects, Glioblastoma multiforme -- Care and treatment -- Drug therapy -- Genetic aspects -- Models, Cancer -- Research, Health care industry
Abstract

STING agonists can reprogram the tumor microenvironment to induce immunological clearance within the central nervous system. Using multiplexed sequential immunofluorescence (SeqIF) and the Ivy Glioblastoma Atlas, STING expression was found in myeloid populations and in the perivascular space. The STING agonist 8803 increased median survival in multiple preclinical models of glioblastoma, including QPP8, an immune checkpoint blockade-resistant model, where 100% of mice were cured. Ex vivo flow cytometry profiling during the therapeutic window demonstrated increases in myeloid tumor trafficking and activation, alongside enhancement of [CD8.sup.+] T cell and NK effector responses. Treatment with 8803 reprogrammed microglia to express costimulatory CD80/CD86 and iNOS, while decreasing immunosuppressive CD206 and arginase. In humanized mice, where tumor cell STING is epigenetically silenced, 8803 therapeutic activity was maintained, further attesting to myeloid dependency and reprogramming. Although the combination with a STAT3 inhibitor did not further enhance STING agonist activity, the addition of anti-PD-1 antibodies to 8803 treatment enhanced survival in an immune checkpoint blockade-responsive glioma model. In summary, 8803 as a monotherapy demonstrates marked in vivo therapeutic activity, meriting consideration for clinical translation., Introduction The prognosis of glioblastoma patients is poor, with an approximate median overall survival of 21 months (1). Whereas radiation and chemotherapy are standard treatments at the time of diagnosis, [...]

Published
2024
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5. Combined PI3Kα-mTOR Targeting of Glioma Stem Cells

Author

Eckerdt, Frank D, Bell, Jonathan B, Gonzalez, Christopher, Oh, Michael S, Perez, Ricardo E, Mazewski, Candice, Fischietti, Mariafausta, Goldman, Stewart, Nakano, Ichiro, and Platanias, Leonidas C

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Rare Diseases, Stem Cell Research - Nonembryonic - Non-Human, Clinical Research, Stem Cell Research - Nonembryonic - Human, Brain Cancer, Stem Cell Research, Brain Disorders, Cancer, Neurosciences, Brain Neoplasms, Cell Line, Tumor, Glioma, Humans, Neoplastic Stem Cells, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Spheroids, Cellular, TOR Serine-Threonine Kinases, Thiazoles
Abstract

Glioblastoma (GBM) is the most common and lethal primary intrinsic tumour of the adult brain and evidence indicates disease progression is driven by glioma stem cells (GSCs). Extensive advances in the molecular characterization of GBM allowed classification into proneural, mesenchymal and classical subtypes, and have raised expectations these insights may predict response to targeted therapies. We utilized GBM neurospheres that display GSC characteristics and found activation of the PI3K/AKT pathway in sphere-forming cells. The PI3Kα selective inhibitor alpelisib blocked PI3K/AKT activation and inhibited spheroid growth, suggesting an essential role for the PI3Kα catalytic isoform. p110α expression was highest in the proneural subtype and this was associated with increased phosphorylation of AKT. Further, employing the GBM BioDP, we found co-expression of PIK3CA with the neuronal stem/progenitor marker NES was associated with poor prognosis in PN GBM patients, indicating a unique role for PI3Kα in PN GSCs. Alpelisib inhibited GSC neurosphere growth and these effects were more pronounced in GSCs of the PN subtype. The antineoplastic effects of alpelisib were substantially enhanced when combined with pharmacologic mTOR inhibition. These findings identify the alpha catalytic PI3K isoform as a unique therapeutic target in proneural GBM and suggest that pharmacological mTOR inhibition may sensitize GSCs to selective PI3Kα inhibition.

Published
2020

6. Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma

Author

Ladomersky, Erik, Zhai, Lijie, Lauing, Kristen L, Bell, April, Xu, Jiahui, Kocherginsky, Masha, Zhang, Bin, Wu, Jennifer D, Podojil, Joseph R, Platanias, Leonidas C, Mochizuki, Aaron Y, Prins, Robert M, Kumthekar, Priya, Raizer, Jeffrey J, Dixit, Karan, Lukas, Rimas V, Horbinski, Craig, Wei, Min, Zhou, Changyou, Pawelec, Graham, Campisi, Judith, Grohmann, Ursula, Prendergast, George C, Munn, David H, and Wainwright, Derek A

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Immunology, Brain Cancer, Neurosciences, Clinical Research, Rare Diseases, Orphan Drug, Aging, Cancer, Brain Disorders, Immunotherapy, Adult, Age Factors, Aged, Aged, 80 and over, Animals, B7-H1 Antigen, Brain, CTLA-4 Antigen, Cellular Senescence, Disease Models, Animal, Female, Glioblastoma, Humans, Immune Checkpoint Inhibitors, Immunosuppression Therapy, Indoleamine-Pyrrole 2, 3, -Dioxygenase, Isocitrate Dehydrogenase, Male, Mice, Knockout, Middle Aged, Progression-Free Survival, Oncology & Carcinogenesis, Clinical sciences, Oncology and carcinogenesis
Abstract

PurposeWild-type isocitrate dehydrogenase-expressing glioblastoma (GBM) is the most common and aggressive primary brain tumor with a median age at diagnosis of ≥65 years. It accounts for approximately 90% of all GBMs and has a median overall survival (OS) of

Published
2020

7. Subtype-specific 3D genome alteration in acute myeloid leukaemia

Author

Xu, Jie, Song, Fan, Lyu, Huijue, Kobayashi, Mikoto, Zhang, Baozhen, Zhao, Ziyu, Hou, Ye, Wang, Xiaotao, Luan, Yu, Jia, Bei, Stasiak, Lena, Wong, Josiah Hiu-yuen, Wang, Qixuan, Jin, Qi, Jin, Qiushi, Fu, Yihao, Yang, Hongbo, Hardison, Ross C., Dovat, Sinisa, Platanias, Leonidas C., Diao, Yarui, Yang, Yue, Yamada, Tomoko, Viny, Aaron D., Levine, Ross L., Claxton, David, Broach, James. R., Zheng, Hong, and Yue, Feng

Published
2022
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8. PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

Author

Chen, Hongxia, Bai, Yunpeng, Kobayashi, Michihiro, Xiao, Shiyu, Cai, Wenjie, Barajas, Sergio, Chen, Sisi, Miao, Jinmin, Meke, Frederick Nguele, Vemula, Sasidhar, Ropa, James P., Croop, James M., Boswell, H. Scott, Wan, Jun, Jia, Yuzhi, Liu, Huiping, Li, Loretta S., Altman, Jessica K., Eklund, Elizabeth A., Ji, Peng, Tong, Wei, Band, Hamid, Huang, Danny T., Platanias, Leonidas C., Zhang, Zhong-Yin, and Liu, Yan

Published
2023
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9. Discovery of a signaling feedback circuit that defines interferon responses in myeloproliferative neoplasms

Author

Saleiro, Diana, Wen, Jeremy Q., Kosciuczuk, Ewa M., Eckerdt, Frank, Beauchamp, Elspeth M., Oku, Chidera V., Blyth, Gavin T., Fischietti, Mariafausta, Ilut, Liliana, Colamonici, Marco, Palivos, William, Atsaves, Paula A., Tan, Dean, Kocherginsky, Masha, Weinberg, Rona Singer, Fish, Eleanor N., Crispino, John D., Hoffman, Ronald, and Platanias, Leonidas C.

Published
2022
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10. Noncoding genetic variation in GATA3 increases acute lymphoblastic leukemia risk through local and global changes in chromatin conformation

Author

Yang, Hongbo, Zhang, Hui, Luan, Yu, Liu, Tingting, Yang, Wentao, Roberts, Kathryn G., Qian, Mao-xiang, Zhang, Bo, Yang, Wenjian, Perez-Andreu, Virginia, Xu, Jie, Iyyanki, Sriranga, Kuang, Da, Stasiak, Lena A., Reshmi, Shalini C., Gastier-Foster, Julie, Smith, Colton, Pui, Ching-Hon, Evans, William E., Hunger, Stephen P., Platanias, Leonidas C., Relling, Mary V., Mullighan, Charles G., Loh, Mignon L., Yue, Feng, and Yang, Jun J.

Published
2022
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12. m6A RNA methylation regulates mitochondrial function

Author

Kahl, Michael, primary, Xu, Zhaofa, additional, Arumugam, Saravanan, additional, Edens, Brittany, additional, Fischietti, Mariafausta, additional, Zhu, Allen C, additional, Platanias, Leonidas C, additional, He, Chuan, additional, Zhuang, Xiaoxi, additional, and Ma, Yongchao C, additional

Published
2024
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14. Schlafen 5 as a novel therapeutic target in pancreatic ductal adenocarcinoma

Author

Fischietti, Mariafausta, Eckerdt, Frank, Blyth, Gavin T., Arslan, Ahmet D., Mati, William M., Oku, Chidera V., Perez, Ricardo E., Lee-Chang, Catalina, Kosciuczuk, Ewa M., Saleiro, Diana, Beauchamp, Elspeth M., Lesniak, Maciej S., Verzella, Daniela, Sun, Leyu, Fish, Eleanor N., Yang, Guang-Yu, Qiang, Wenan, and Platanias, Leonidas C.

Published
2021
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17. Genomic Landscape of Advanced Solid Tumors in Circulating Tumor DNA and Correlation With Tissue Sequencing: A Single Institutionʼs Experience

Author

Gerratana, Lorenzo, Movarek, Michael, Wehbe, Firas, Katam, Neelima, Mahalingam, Devalingam, Donahue, Jeannine, Shah, Ami, Chae, Young K., Mulcahy, Mary, Tsarwhas, Dean, Villaflor, Victoria, Kalyan, Aparna, Hussein, Maha, Patel, Jyoti, Chandra, Sunandana, Platanias, Leonidas C., Gradishar, William, Cristofanilli, Massimo, and Behdad, Amir

Published
2022
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18. Signaling by Type I Interferons in Immune Cells: Disease Consequences.

Author

Zannikou, Markella, Fish, Eleanor N., and Platanias, Leonidas C.

Subjects
CELL proliferation, IMMUNE system, CELLULAR signal transduction, INTERFERONS, METASTASIS, DISEASE progression
Abstract

Simple Summary: IFNs are cytokines that play critical roles in the immune defense mechanisms that prevent virus spread. They also exhibit regulatory effects on the immune system and contribute to the elimination of malignant cells. These cytokines mediate their effects by binding on unique receptors on the surface of immune cells, initiating signaling cascades that trigger expression of IFN-stimulated genes (ISGs) that ultimately drive expression of specific proteins that mediate the various interferon responses and effects. In this review, we discuss the mechanisms by which interferons control different types of cells of the immune system, as well as malignant cells to mediate their important biological properties. This review addresses interferon (IFN) signaling in immune cells and the tumor microenvironment (TME) and examines how this affects cancer progression. The data reveal that IFNs exert dual roles in cancers, dependent on the TME, exhibiting both anti-tumor activity and promoting cancer progression. We discuss the abnormal IFN signaling induced by cancerous cells that alters immune responses to permit their survival and proliferation. [ABSTRACT FROM AUTHOR]

Published
2024
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20. PRL2 phosphatase promotes oncogenic KIT signaling in leukemia cells through modulating CBL phosphorylation

Author

Chen, Hongxia, primary, Bai, Yunpeng, additional, Kobayashi, Michihiro, additional, Xiao, Shiyu, additional, Barajas, Sergio, additional, Cai, Wenjie, additional, Chen, Sisi, additional, Miao, Jinmin, additional, Nguele Meke, Frederick, additional, Yao, Chonghua, additional, Yang, Yuxia, additional, Strube, Katherine, additional, Satchivi, Odelia, additional, Sun, Jianmin, additional, Ronnstrand, Lars, additional, Croop, James M., additional, Boswell, H Scott, additional, Jia, Yuzhi, additional, Liu, Huiping, additional, Li, Loretta S., additional, Altman, Jessica K., additional, Eklund, Elizabeth A., additional, Sukhanova, Madina, additional, Ji, Peng, additional, Tong, Wei, additional, Band, Hamid, additional, Huang, Danny T., additional, Platanias, Leonidas C., additional, Zhang, Zhong-Yin, additional, and Liu, Yan, additional

Published
2023
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21. Supplementary Video S20 from Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer

Author

Dashzeveg, Nurmaa K., primary, Jia, Yuzhi, primary, Zhang, Youbin, primary, Gerratana, Lorenzo, primary, Patel, Priyam, primary, Shajahan, Asif, primary, Dandar, Tsogbadrakh, primary, Ramos, Erika K., primary, Almubarak, Hannah F., primary, Adorno-Cruz, Valery, primary, Taftaf, Rokana, primary, Schuster, Emma J., primary, Scholten, David, primary, Sokolowski, Michael T., primary, Reduzzi, Carolina, primary, El-Shennawy, Lamiaa, primary, Hoffmann, Andrew D., primary, Manai, Maroua, primary, Zhang, Qiang, primary, D'Amico, Paolo, primary, Azadi, Parastoo, primary, Colley, Karen J., primary, Platanias, Leonidas C., primary, Shah, Ami N., primary, Gradishar, William J., primary, Cristofanilli, Massimo, primary, Muller, William A., primary, Cobb, Brian A., primary, and Liu, Huiping, primary

Published
2023
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22. Supplementary Excel S3 from Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer

Author

Dashzeveg, Nurmaa K., primary, Jia, Yuzhi, primary, Zhang, Youbin, primary, Gerratana, Lorenzo, primary, Patel, Priyam, primary, Shajahan, Asif, primary, Dandar, Tsogbadrakh, primary, Ramos, Erika K., primary, Almubarak, Hannah F., primary, Adorno-Cruz, Valery, primary, Taftaf, Rokana, primary, Schuster, Emma J., primary, Scholten, David, primary, Sokolowski, Michael T., primary, Reduzzi, Carolina, primary, El-Shennawy, Lamiaa, primary, Hoffmann, Andrew D., primary, Manai, Maroua, primary, Zhang, Qiang, primary, D'Amico, Paolo, primary, Azadi, Parastoo, primary, Colley, Karen J., primary, Platanias, Leonidas C., primary, Shah, Ami N., primary, Gradishar, William J., primary, Cristofanilli, Massimo, primary, Muller, William A., primary, Cobb, Brian A., primary, and Liu, Huiping, primary

Published
2023
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23. Data from Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer

Author

Dashzeveg, Nurmaa K., primary, Jia, Yuzhi, primary, Zhang, Youbin, primary, Gerratana, Lorenzo, primary, Patel, Priyam, primary, Shajahan, Asif, primary, Dandar, Tsogbadrakh, primary, Ramos, Erika K., primary, Almubarak, Hannah F., primary, Adorno-Cruz, Valery, primary, Taftaf, Rokana, primary, Schuster, Emma J., primary, Scholten, David, primary, Sokolowski, Michael T., primary, Reduzzi, Carolina, primary, El-Shennawy, Lamiaa, primary, Hoffmann, Andrew D., primary, Manai, Maroua, primary, Zhang, Qiang, primary, D'Amico, Paolo, primary, Azadi, Parastoo, primary, Colley, Karen J., primary, Platanias, Leonidas C., primary, Shah, Ami N., primary, Gradishar, William J., primary, Cristofanilli, Massimo, primary, Muller, William A., primary, Cobb, Brian A., primary, and Liu, Huiping, primary

Published
2023
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24. Supplementary Tables S1-S2 from Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer

Author

Dashzeveg, Nurmaa K., primary, Jia, Yuzhi, primary, Zhang, Youbin, primary, Gerratana, Lorenzo, primary, Patel, Priyam, primary, Shajahan, Asif, primary, Dandar, Tsogbadrakh, primary, Ramos, Erika K., primary, Almubarak, Hannah F., primary, Adorno-Cruz, Valery, primary, Taftaf, Rokana, primary, Schuster, Emma J., primary, Scholten, David, primary, Sokolowski, Michael T., primary, Reduzzi, Carolina, primary, El-Shennawy, Lamiaa, primary, Hoffmann, Andrew D., primary, Manai, Maroua, primary, Zhang, Qiang, primary, D'Amico, Paolo, primary, Azadi, Parastoo, primary, Colley, Karen J., primary, Platanias, Leonidas C., primary, Shah, Ami N., primary, Gradishar, William J., primary, Cristofanilli, Massimo, primary, Muller, William A., primary, Cobb, Brian A., primary, and Liu, Huiping, primary

Published
2023
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25. Supplementary Figures S1-S17 from Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer

Author

Dashzeveg, Nurmaa K., primary, Jia, Yuzhi, primary, Zhang, Youbin, primary, Gerratana, Lorenzo, primary, Patel, Priyam, primary, Shajahan, Asif, primary, Dandar, Tsogbadrakh, primary, Ramos, Erika K., primary, Almubarak, Hannah F., primary, Adorno-Cruz, Valery, primary, Taftaf, Rokana, primary, Schuster, Emma J., primary, Scholten, David, primary, Sokolowski, Michael T., primary, Reduzzi, Carolina, primary, El-Shennawy, Lamiaa, primary, Hoffmann, Andrew D., primary, Manai, Maroua, primary, Zhang, Qiang, primary, D'Amico, Paolo, primary, Azadi, Parastoo, primary, Colley, Karen J., primary, Platanias, Leonidas C., primary, Shah, Ami N., primary, Gradishar, William J., primary, Cristofanilli, Massimo, primary, Muller, William A., primary, Cobb, Brian A., primary, and Liu, Huiping, primary

Published
2023
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27. Longitudinal Dynamics of Circulating Tumor Cells and Circulating Tumor DNA for Treatment Monitoring in Metastatic Breast Cancer

Author

Gerratana, Lorenzo, Davis, Andrew A., Zhang, Qiang, Basile, Debora, Rossi, Giovanna, Strickland, Kimberly, Franzoni, Alessandra, Allegri, Lorenzo, Mu, Zhaomei, Zhang, Youbin, Flaum, Lisa E., Damante, Giuseppe, Gradishar, William John, Platanias, Leonidas C., Behdad, Amir, Yang, Hushan, Puglisi, Fabio, and Cristofanilli, Massimo

Published
2021
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28. Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer

Author

Dashzeveg, Nurmaa K., primary, Jia, Yuzhi, additional, Zhang, Youbin, additional, Gerratana, Lorenzo, additional, Patel, Priyam, additional, Shajahan, Asif, additional, Dandar, Tsogbadrakh, additional, Ramos, Erika K., additional, Almubarak, Hannah F., additional, Adorno-Cruz, Valery, additional, Taftaf, Rokana, additional, Schuster, Emma J., additional, Scholten, David, additional, Sokolowski, Michael T., additional, Reduzzi, Carolina, additional, El-Shennawy, Lamiaa, additional, Hoffmann, Andrew D., additional, Manai, Maroua, additional, Zhang, Qiang, additional, D'Amico, Paolo, additional, Azadi, Parastoo, additional, Colley, Karen J., additional, Platanias, Leonidas C., additional, Shah, Ami N., additional, Gradishar, William J., additional, Cristofanilli, Massimo, additional, Muller, William A., additional, Cobb, Brian A., additional, and Liu, Huiping, additional

Published
2023
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30. Enhancement and Implementation of a Health Information Technology Module to Improve the Discrete Capture of Cancer Staging in a Diverse Regional Health System

Author

Walesa, Macy B., primary, Denny, Ashley, additional, Patel, Alpa, additional, Mulcahy, Mary, additional, Kircher, Sheetal, additional, George, Christopher, additional, Tsarwhas, Dean, additional, Ross, Ashley, additional, Platanias, Leonidas C., additional, Poylin, Vitaly, additional, Yang, Anthony D., additional, Barnard, Cynthia, additional, Bilimoria, Karl Y., additional, and Merkow, Ryan P., additional

Published
2023
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36. FIGURE 4 from Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells

Author

Saleiro, Diana, primary, Kosciuczuk, Ewa M., primary, Fischietti, Mariafausta, primary, Perez, Ricardo E., primary, Yang, G. Sohae, primary, Eckerdt, Frank, primary, Beauchamp, Elspeth M., primary, Hou, Ye, primary, Wang, Qixuan, primary, Weinberg, Rona Singer, primary, Fish, Eleanor N., primary, Yue, Feng, primary, Hoffman, Ronald, primary, and Platanias, Leonidas C., primary

Published
2023
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37. Figure S1 from Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells

Author

Saleiro, Diana, primary, Kosciuczuk, Ewa M., primary, Fischietti, Mariafausta, primary, Perez, Ricardo E., primary, Yang, G. Sohae, primary, Eckerdt, Frank, primary, Beauchamp, Elspeth M., primary, Hou, Ye, primary, Wang, Qixuan, primary, Weinberg, Rona Singer, primary, Fish, Eleanor N., primary, Yue, Feng, primary, Hoffman, Ronald, primary, and Platanias, Leonidas C., primary

Published
2023
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38. FIGURE 1 from Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells

Author

Saleiro, Diana, primary, Kosciuczuk, Ewa M., primary, Fischietti, Mariafausta, primary, Perez, Ricardo E., primary, Yang, G. Sohae, primary, Eckerdt, Frank, primary, Beauchamp, Elspeth M., primary, Hou, Ye, primary, Wang, Qixuan, primary, Weinberg, Rona Singer, primary, Fish, Eleanor N., primary, Yue, Feng, primary, Hoffman, Ronald, primary, and Platanias, Leonidas C., primary

Published
2023
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39. FIGURE 2 from Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells

Author

Saleiro, Diana, primary, Kosciuczuk, Ewa M., primary, Fischietti, Mariafausta, primary, Perez, Ricardo E., primary, Yang, G. Sohae, primary, Eckerdt, Frank, primary, Beauchamp, Elspeth M., primary, Hou, Ye, primary, Wang, Qixuan, primary, Weinberg, Rona Singer, primary, Fish, Eleanor N., primary, Yue, Feng, primary, Hoffman, Ronald, primary, and Platanias, Leonidas C., primary

Published
2023
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40. FIGURE 3 from Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells

Author

Saleiro, Diana, primary, Kosciuczuk, Ewa M., primary, Fischietti, Mariafausta, primary, Perez, Ricardo E., primary, Yang, G. Sohae, primary, Eckerdt, Frank, primary, Beauchamp, Elspeth M., primary, Hou, Ye, primary, Wang, Qixuan, primary, Weinberg, Rona Singer, primary, Fish, Eleanor N., primary, Yue, Feng, primary, Hoffman, Ronald, primary, and Platanias, Leonidas C., primary

Published
2023
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41. Data from Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells

Author

Saleiro, Diana, primary, Kosciuczuk, Ewa M., primary, Fischietti, Mariafausta, primary, Perez, Ricardo E., primary, Yang, G. Sohae, primary, Eckerdt, Frank, primary, Beauchamp, Elspeth M., primary, Hou, Ye, primary, Wang, Qixuan, primary, Weinberg, Rona Singer, primary, Fish, Eleanor N., primary, Yue, Feng, primary, Hoffman, Ronald, primary, and Platanias, Leonidas C., primary

Published
2023
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46. Computational ranking-assisted identification of Plexin-B2 in homotypic and heterotypic clustering of circulating tumor cells in breast cancer metastasis

Author

Schuster, Emma, primary, Dashzeveg, Nurmaa, additional, Jia, Yuzhi, additional, Golam, Kibria, additional, Zhang, Tong, additional, Hoffman, Andrew, additional, Zhang, Youbin, additional, Zheng, Chunlei, additional, Ramos, Erika, additional, Taftaf, Rokana, additional, Shennawy, Lamiaa El-, additional, Scholten, David, additional, Kitata, Reta B., additional, Adorno-Cruz, Valery, additional, Reduzzi, Carolina, additional, Spahija, Sabina, additional, Xu, Rong, additional, Siziopikou, Kalliopi P., additional, Platanias, Leonidas C., additional, Shah, Ami, additional, Gradishar, William J., additional, Cristofanilli, Massimo, additional, Tsai, Chia-Feng, additional, Shi, Tujin, additional, and Liu, Huiping, additional

Published
2023
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47. Data from Myeloid-Derived Suppressive Cells Promote B cell–Mediated Immunosuppression via Transfer of PD-L1 in Glioblastoma

Author

Lee-Chang, Catalina, primary, Rashidi, Aida, primary, Miska, Jason, primary, Zhang, Peng, primary, Pituch, Katarzyna C., primary, Hou, David, primary, Xiao, Ting, primary, Fischietti, Mariafausta, primary, Kang, Seong Jae, primary, Appin, Christina L., primary, Horbinski, Craig, primary, Platanias, Leonidas C., primary, Lopez-Rosas, Aurora, primary, Han, Yu, primary, Balyasnikova, Irina V., primary, and Lesniak, Maciej S., primary

Published
2023
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48. Supplementary Table S2 from SLFN11 Negatively Regulates Noncanonical NFκB Signaling to Promote Glioblastoma Progression

Author

Fischietti, Mariafausta, primary, Eckerdt, Frank, primary, Perez, Ricardo E., primary, Guillen Magaña, Jamie N., primary, Mazewski, Candice, primary, Ho, Sang, primary, Gonzalez, Christopher, primary, Streich, Lukas D., primary, Beauchamp, Elspeth M., primary, Heimberger, Amy B., primary, Baran, Aneta H., primary, Yue, Feng, primary, James, C. David, primary, and Platanias, Leonidas C., primary

Published
2023
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49. Supplementary Figures from Myeloid-Derived Suppressive Cells Promote B cell–Mediated Immunosuppression via Transfer of PD-L1 in Glioblastoma

Author

Lee-Chang, Catalina, primary, Rashidi, Aida, primary, Miska, Jason, primary, Zhang, Peng, primary, Pituch, Katarzyna C., primary, Hou, David, primary, Xiao, Ting, primary, Fischietti, Mariafausta, primary, Kang, Seong Jae, primary, Appin, Christina L., primary, Horbinski, Craig, primary, Platanias, Leonidas C., primary, Lopez-Rosas, Aurora, primary, Han, Yu, primary, Balyasnikova, Irina V., primary, and Lesniak, Maciej S., primary

Published
2023
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50. Supplementary Figures S1-S3, Table S1 from SLFN11 Negatively Regulates Noncanonical NFκB Signaling to Promote Glioblastoma Progression

Author

Fischietti, Mariafausta, primary, Eckerdt, Frank, primary, Perez, Ricardo E., primary, Guillen Magaña, Jamie N., primary, Mazewski, Candice, primary, Ho, Sang, primary, Gonzalez, Christopher, primary, Streich, Lukas D., primary, Beauchamp, Elspeth M., primary, Heimberger, Amy B., primary, Baran, Aneta H., primary, Yue, Feng, primary, James, C. David, primary, and Platanias, Leonidas C., primary

Published
2023
Full Text
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