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249 results on '"Plöckinger, U"'

1. Management goals for type 1 Gaucher disease: An expert consensus document from the European working group on Gaucher disease

Author

Biegstraaten, M., Cox, T.M., Belmatoug, N., Berger, M.G., Collin-Histed, T., Vom Dahl, S., Di Rocco, M., Fraga, C., Giona, F., Giraldo, P., Hasanhodzic, M., Hughes, D.A., Iversen, P.O., Kiewiet, A.I., Lukina, E., Machaczka, M., Marinakis, T., Mengel, E., Pastores, G.M., Plöckinger, U., Rosenbaum, H., Serratrice, C., Symeonidis, A., Szer, J., Timmerman, J., Tylki-Szymańska, A., Weisz Hubshman, M., Zafeiriou, D.I., Zimran, A., and Hollak, C.E.M.

Published
2018
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19. ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Biochemical Markers

Author

O'Toole, D., Grossman, A., Gross, D., Fave, G. D., Barkmanova, J., O'Connor, J., Pape, U. F., Plöckinger, U., Åkerström, G., Annibale, B., Arnold, R., Bajetta, E., Chen, Y. J., Costa, F., Couvelard, A., Davar, J., Herder, W. D., Eriksson, B., Falconi, M., Ferone, D., Gustafsson, B., Hyrdel, R., Ivan, D., Kaltsas, G., Kianmanesh, R., Klöppel, G., Knigge, U. P., Komminoth, P., Kos Kudla, B., Kwekkeboom, D., Lebtahi, R., Lewington, V., Mcnicol, A. M., Mitry, E., Nilsson, O., Öberg, K., Papotti, M., Pavel, M., Perren, A., Platania, M., Rindi, G., Ruszniewski, P., Salazar, R., Scarpa, Aldo, Scheidhauer, K., Scoazec, J. Y., Sundin, A., Szpak, W., Taal, B., Vitek, P., Vullierme, M. P., and Wiedenmann, B.

Subjects
Endocrinology, Diabetes and Metabolism, Diagnostic accuracy, insulinoma, Neuroendocrine tumors, Bioinformatics, secretin, 0302 clinical medicine, Endocrinology, immune system diseases, cancer diagnosis, conference paper, Biochemical markers, biology, Urinary 5-hydroxyindoleacetic acid, Chromogranin A, Fasting, Hydroxyindoleacetic Acid, Diabetes and Metabolism, Neuroendocrine Tumors, priority journal, 030220 oncology & carcinogenesis, diagnostic accuracy, 5 hydroxyindoleacetic acid, neuroendocrine tumor, hormones, hormone substitutes, and hormone antagonists, Neuroendocrine tumor test, musculoskeletal diseases, medicine.medical_specialty, Standard of care, MEDLINE, 610 Medicine & health, 030209 endocrinology & metabolism, 03 medical and health sciences, Cellular and Molecular Neuroscience, Patient information, Internal medicine, gastrin, medicine, Humans, biochemistry, human, Insulinoma, Gastrinoma, gastrinoma, Endocrine and Autonomic Systems, business.industry, practice guideline, biochemical marker, chromogranin A, hypoglycemia, patient information, medicine.disease, body regions, biology.protein, 570 Life sciences, Biomarkers, business
Abstract

Biomarkers have been the mainstay in the diagnosis and follow-up of patients with neuroendocrine tumors (NETs) over the last few decades. In the beginning, secretory products from a variety of subtypes of NETs were regarded as biomarkers to follow during diagnosis and treatment: serotonin for small intestinal (SI) NETs, and gastrin and insulin for pancreatic NETs. However, it became evident that a large number of NETs were so-called nonfunctioning tumors without secreting substances that caused hormone-related symptoms. Therefore, it was necessary to develop so-called “general tumor markers.” The most important ones so far have been chromogranin A and neuron-specific enolase (NSE). Chromogranin A is the most important general biomarker for most NETs with a sensitivity and specificity somewhere between 60 and 90%. NSE has been a relevant biomarker for patients with high-grade tumors, particularly lung and gastrointestinal tract tumors. Serotonin and the breakdown product urinary 5-hydroxyindoleacetic acid (U-5-HIAA) is still an important marker for diagnosing and follow-up of SI NETs. Recently, 5-HIAA in plasma has been analyzed by high-performance liquid chromatography and fluorometric detection and has shown good agreement with U-5-HIAA analysis. In the future, we will see new tests including circulating tumor cells, circulating DNA and mRNA. Recently, a NET test has been developed analyzing gene transcripts in circulating blood. Preliminary data indicate high sensitivity and specificity for NETs. However, its precise role has to be validated in prospective randomized controlled trials which are ongoing right now.

Published
2017
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20. An integrative correlation of myopathology, phenotype and genotype in late onset Pompe disease

Author

Kulessa, M., primary, Weyer‐Menkhoff, I., additional, Viergutz, L., additional, Kornblum, C., additional, Claeys, K. G., additional, Schneider, I., additional, Plöckinger, U., additional, Young, P., additional, Boentert, M., additional, Vielhaber, S., additional, Mawrin, C., additional, Bergmann, M., additional, Weis, J., additional, Ziagaki, A., additional, Stenzel, W., additional, Deschauer, M., additional, Nolte, D., additional, Hahn, A., additional, Schoser, B., additional, and Schänzer, A., additional

Published
2019
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22. ENETS Consensus Guidelines for the Management of Patients with Liver and Other Distant Metastases from Neuroendocrine Neoplasms of Foregut, Midgut, Hindgut, and Unknown Primary

Author

M. Pavel, E. Baudin, A. Couvelard, E. Krenning, K. Öberg, T. Steinmüller, M. Anlauf, B. Wiedenmann, R. Salazar, B. C. Conference Anlauf M, Arnold R, Bartsch D, Baudin E, Baum R, Brandi ML, Cadiot G, Costa F, Caplin M, Couvelard A, de Herder W, Delle Fave G, Denecke T, Eriksson B, Gress T, Gross D, Grossman A, Jensen R, Kaltsas G, Kelestimur F, Kianmanesh R, Klöppel G, Klose KJ, Knigge U, Komminoth P, Kos Kudla B, Krenning E, Kwekkeboom D, Lopes JM, Niederle B, Nilsson O, Öberg K, O'Connor J, O'Toole D, Pape UF, Papotti M, Pascher A, Pavel M, Perren A, Plöckinger U, Rindi G, Ruszniewski P, Salazar R, Sasano H, Sauvanet A, Scoazec JY, Steinmüller T, Sundin A, Taal B, Tomassetti P, Van Cutsem E, Vullierme MP, Wiedenmann B., FALCONI , MASSIMO, M., Pavel, E., Baudin, A., Couvelard, E., Krenning, K., Öberg, T., Steinmüller, M., Anlauf, B., Wiedenmann, R., Salazar, B. C., Conference Anlauf M, Arnold, R, Bartsch, D, Baudin, E, Baum, R, Brandi, Ml, Cadiot, G, Costa, F, Caplin, M, Couvelard, A, de Herder, W, Delle Fave, G, Denecke, T, Eriksson, B, Falconi, Massimo, Gress, T, Gross, D, Grossman, A, Jensen, R, Kaltsas, G, Kelestimur, F, Kianmanesh, R, Klöppel, G, Klose, Kj, Knigge, U, Komminoth, P, Kos Kudla, B, Krenning, E, Kwekkeboom, D, Lopes, Jm, Niederle, B, Nilsson, O, Öberg, K, O'Connor, J, O'Toole, D, Pape, Uf, Papotti, M, Pascher, A, Pavel, M, Perren, A, Plöckinger, U, Rindi, G, Ruszniewski, P, Salazar, R, Sasano, H, Sauvanet, A, Scoazec, Jy, Steinmüller, T, Sundin, A, Taal, B, Tomassetti, P, Van Cutsem, E, Vullierme, Mp, Wiedenmann, B., and Radiology & Nuclear Medicine

Subjects
medicine.medical_specialty, animal structures, Endocrinology, Diabetes and Metabolism, Intestinal Neoplasm, Neuroendocrine tumors, Biology, digestive system, Cellular and Molecular Neuroscience, Endocrinology, stomatognathic system, Internal medicine, Intestinal Neoplasms, medicine, Humans, Endocrine and Autonomic Systems, Liver Neoplasms, fungi, Midgut, Hindgut, Foregut, medicine.disease, Neuroendocrine Tumors, embryonic structures, Unknown primary, Neoplasms, Unknown Primary
Abstract

ENETS Consensus Guidelines for the Management of Patients with Liver and Other Distant Metastases from Neuroendocrine Neoplasms of Foregut, Midgut, Hindgut, and Unknown Primary

Published
2012
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23. ENETS Consensus Guidelines for the Management of Patients with Neuroendocrine Neoplasms from the Jejuno-Ileum and the Appendix Including Goblet Cell Carcinomas

Author

U. Pape, A. Perren, B. Niederle, D. Gross, T. Gress, F. Costa, R. Arnold, T. Denecke, U. Plöckinger, R. Salazar, A. Grossman, B. C. Conference Anlauf M, Arnold R, Bartsch D, Baudin E, Baum R, Brandi ML, Cadiot G, Costa F, Caplin M, Couvelard A, de Herder W, Delle Fave G, Denecke T, Eriksson B, Gress T, Gross D, Grossman A, Jensen R, Kaltsas G, Kelestimur F, Kianmanesh R, Klöppel G, Klose KJ, Knigge U, Komminoth P, Kos Kudla B, Krenning E, Kwekkeboom D, Lopes JM, Niederle B, Nilsson O, Öberg K, O'Connor J, O'Toole D, Pape UF, Papotti M, Pascher A, Pavel M, Perren A, Plöckinger U, Rindi G, Ruszniewski P, Salazar R, Sasano H, Sauvanet A, Scoazec JY, Steinmüller T, Sundin A, Taal B, Tomassetti P, Van Cutsem E, Vullierme MP, Wiedenmann B., FALCONI , MASSIMO, Erasmus MC other, U., Pape, A., Perren, B., Niederle, D., Gro, T., Gre, F., Costa, R., Arnold, T., Denecke, U., Plöckinger, R., Salazar, A., Grossman, B. C., Conference Anlauf M, Arnold, R, Bartsch, D, Baudin, E, Baum, R, Brandi, Ml, Cadiot, G, Costa, F, Caplin, M, Couvelard, A, de Herder, W, Delle Fave, G, Denecke, T, Eriksson, B, Falconi, Massimo, Gress, T, Gross, D, Grossman, A, Jensen, R, Kaltsas, G, Kelestimur, F, Kianmanesh, R, Klöppel, G, Klose, Kj, Knigge, U, Komminoth, P, Kos Kudla, B, Krenning, E, Kwekkeboom, D, Lopes, Jm, Niederle, B, Nilsson, O, Öberg, K, O'Connor, J, O'Toole, D, Pape, Uf, Papotti, M, Pascher, A, Pavel, M, Perren, A, Plöckinger, U, Rindi, G, Ruszniewski, P, Salazar, R, Sasano, H, Sauvanet, A, Scoazec, Jy, Steinmüller, T, Sundin, A, Taal, B, Tomassetti, P, Van Cutsem, E, Vullierme, Mp, and Wiedenmann, B.

Subjects
medicine.medical_specialty, Endocrine and Autonomic Systems, business.industry, Endocrinology, Diabetes and Metabolism, General surgery, University hospital, Appendix, Appendiceal neoplasms, Neuroendocrine Tumors, Cellular and Molecular Neuroscience, Jejunum, Endocrinology, medicine.anatomical_structure, Appendiceal Neoplasms, Ileum, Internal medicine, Intestinal Neoplasms, neuroendocrine neoplasms from the jejuno-ileum and the appendix including goblet cell carcinomas, medicine, Humans, business
Abstract

a Division of Hepatology and Gastroenterology, Department of Internal Medicine, Campus Virchow-Klinikum, Charite-Universitatsmedizin Berlin, Berlin , Germany; b Department of Pathology, Universitatsspital, Zurich , Switzerland; c Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna , Austria; d Department of Endocrinology and Metabolism, Hadassah University Hospital, Jerusalem , Israel; e Department of Internal Medicine, Philipps University, Marburg , Germany; f Hopital Sirio Libanes, Centro de Oncologia, Sao Paulo , Brazil; g Department of Radiology, Campus Virchow-Klinikum, Charite, University Medicine Berlin, Berlin , Germany; h Department of Oncology, Institut Catala d’Oncologia (IDIBELL), Barcelona , Spain; i Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, University of Oxford, Oxford , UK

Published
2012
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24. An integrative correlation of myopathology, phenotype and genotype in late onset Pompe disease.

Author

Kulessa, M., Weyer‐Menkhoff, I., Viergutz, L., Kornblum, C., Claeys, K. G., Schneider, I., Plöckinger, U., Young, P., Boentert, M., Vielhaber, S., Mawrin, C., Bergmann, M., Weis, J., Ziagaki, A., Stenzel, W., Deschauer, M., Nolte, D., Hahn, A., Schoser, B., and Schänzer, A.

Subjects
GLYCOGEN storage disease type II, AUTOPHAGY, SKELETAL muscle, GENOTYPES, MICROTUBULE-associated proteins
Abstract

Aims: Pompe disease is caused by pathogenic mutations in the alpha 1,4‐glucosidase (GAA) gene and in patients with late onset Pome disease (LOPD), genotype–phenotype correlations are unpredictable. Skeletal muscle pathology includes glycogen accumulation and altered autophagy of various degrees. A correlation of the muscle morphology with clinical features and the genetic background in GAA may contribute to the understanding of the phenotypic variability. Methods: Muscle biopsies taken before enzyme replacement therapy were analysed from 53 patients with LOPD. On resin sections, glycogen accumulation, fibrosis, autophagic vacuoles and the degree of muscle damage (morphology‐score) were analysed and the results were compared with clinical findings. Additional autophagy markers microtubule‐associated protein 1A/1B‐light chain 3, p62 and Bcl2‐associated athanogene 3 were analysed on cryosections from 22 LOPD biopsies. Results: The myopathology showed a high variability with, in most patients, a moderate glycogen accumulation and a low morphology‐score. High morphology‐scores were associated with increased fibrosis and autophagy highlighting the role of autophagy in severe stages of skeletal muscle damage. The morphology‐score did not correlate with the patient's age at biopsy, disease duration, nor with the residual GAA enzyme activity or creatine‐kinase levels. In 37 patients with LOPD, genetic analysis identified the most frequent mutation, c.‐32‐13T>G, in 95%, most commonly in combination with c.525delT (19%). No significant correlation was found between the different GAA genotypes and muscle morphology type. Conclusions: Muscle morphology in LOPD patients shows a high variability with, in most cases, moderate pathology. Increased pathology is associated with more fibrosis and autophagy. [ABSTRACT FROM AUTHOR]

Published
2020
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25. Rare functioning pancreatic endocrine tumors

Author

O'Toole D, Salazar R, Kaltsas G, Couvelard A, De Herder WW, Hyrdel R, Nikou G, Krenning E, Vullierme MP, Caplin M, Jensen R, Eriksson B, Ahlman H, Arnold R, Bechstein WO, Cadiot G, Christ E, Chung D, Delle Fave G, Falchetti A, Ferone D, Goretzki P, Gross D, Hochhauser D, Keleştimur F, Kianmanesh R, Knapp W, Knigge UP, Komminoth P, Körner M, Kos Kudła B, Kvols L, Kwekkeboom DJ, Lewington V, Lopes JM, Manfredi R, McNicol AM, Mitry E, Niederle B, Nilsson O, Öberg K, O'Connor J, Pauwels S, Pape UF, Pavel M, Perren A, Plöckinger U, Ramage J, Ricke J, Rindi G, Ruszniewski P, Sauvanet A, Scarpa A, Scoazec JY, Sevilla Garcia MI, Steinmüller T, Sundin A, Taal B, Van Cutsem E, Wiedenmann B, Wildi S, Yao JC, Zgliczynski S., FALCONI , MASSIMO, Internal Medicine, Radiology & Nuclear Medicine, O'Toole, D, Salazar, R, Falconi, Massimo, Kaltsas, G, Couvelard, A, De Herder, Ww, Hyrdel, R, Nikou, G, Krenning, E, Vullierme, Mp, Caplin, M, Jensen, R, Eriksson, B, Ahlman, H, Arnold, R, Bechstein, Wo, Cadiot, G, Christ, E, Chung, D, Delle Fave, G, Falchetti, A, Ferone, D, Goretzki, P, Gross, D, Hochhauser, D, Keleştimur, F, Kianmanesh, R, Knapp, W, Knigge, Up, Komminoth, P, Körner, M, Kos Kudła, B, Kvols, L, Kwekkeboom, Dj, Lewington, V, Lopes, Jm, Manfredi, R, Mcnicol, Am, Mitry, E, Niederle, B, Nilsson, O, Öberg, K, O'Connor, J, Pauwels, S, Pape, Uf, Pavel, M, Perren, A, Plöckinger, U, Ramage, J, Ricke, J, Rindi, G, Ruszniewski, P, Sauvanet, A, Scarpa, A, Scoazec, Jy, Sevilla Garcia, Mi, Steinmüller, T, Sundin, A, Taal, B, Van Cutsem, E, Wiedenmann, B, Wildi, S, Yao, Jc, and Zgliczynski, S.

Subjects
medicine.medical_specialty, Endocrine and Autonomic Systems, Endocrinology, Diabetes and Metabolism, Humans, Neuroendocrine Tumors, Pancreatic Neoplasms, Biology, University hospital, Cellular and Molecular Neuroscience, Endocrinology, Internal medicine, medicine
Abstract

a Department of Gastroenterology, Beaujon Hospital, Clichy , France; b Department of Oncology, Institut Catala d’Oncologia, Barcelona , Spain; c Department of Surgery, Verona University, Verona , Italy; d Department of Endocrinology and Metabolism, Genimatas Hospital, Athens , Greece; e Department of Gastroenterology, Beaujon Hospital, Clichy , France; f Department of Endocrinology, Erasmus MC University, Rotterdam , The Netherlands; g Department of Internal Medicine, Martin University, Martin , Slovakia; h Department of Propaedeutic Internal Medicine, Laiko Hospital, Athens , Greece; i Department of Nuclear Medicine, Erasmus MC University, Rotterdam , The Netherlands; j Department of Gastroenterology, Beaujon Hospital, Clichy , France; k Department of Gastroenterology, Royal Free Hospital, London , UK; l Department of Cell Biology, National Institute of Health, Bethesda, Md. , USA; m Department of Endocrinology, University Hospital, Uppsala , Sweden

Published
2006

26. ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors:Echocardiography

Author

Plöckinger, U., Gustafsson, B., Ivan, D., Szpak, W., Davar, J., Åkerstrom, G., Annibale, B., Arnold, R., Bajetta, E., Barkmanova, J., Chen, Y. J., Costa, F., Couvelard, A., Herder, W. D., Fave, G. D., Eriksson, B., Falconi, M., Ferone, D., Gross, D., Grossman, A., Hyrdel, R., Kaltsas, G., Kianmanesh, R., Klöppel, G., Knigge, U. P., Komminoth, P., Kos Kudla, B., Kwekkeboom, D., Lebtahi, R., Lewington, V., Mcnicol, A. M., Mitry, E., Nilsson, O., Öberg, K., O'Connor, J., O'Toole, D., Pape, U. F., Papotti, M., Pavel, M., Perren, A., Platania, M., Rindi, G., Ruszniewski, P., Salazar, R., Scarpa, Aldo, Scheidhauer, K., Scoazec, J. Y., Sundin, A., Taal, B., Vitek, P., Vullierme, M. P., and Wiedenmann, B.

Subjects
medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Carcinoid tumors, MEDLINE, Carcinoid Heart Disease, carcinoid syndrome, Diagnostic accuracy, Disease, Neuroendocrine tumors, Cellular and Molecular Neuroscience, Endocrinology, cancer diagnosis, Internal medicine, Humans, echocardiography, Medicine, human, medical society, conference paper, medical documentation, Endocrine and Autonomic Systems, business.industry, practice guideline, Medical practice, diagnostic accuracy, medical practice, neuroendocrine tumor, patient information, priority journal, medicine.disease, Medical documents, Neuroendocrine Tumors, business, Carcinoid syndrome
Abstract

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors : echocardiography.

Published
2009
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28. Consensus guidelines for the management of patients with liver metastases from digestive (neuro) endocrine tumors: Foregut, midgut, hindgut, and unknown primary

Author

Steinmüller, T., Kianmanesh, R., Falconi, Massimo, Scarpa, Aldo, Taal, B., Kwekkeboom, D., Lopes, J., Perren, A., Nikou, G., Yao, J., Fave, G. D., O'Toole, D., Ahlman, H., Arnold, R., Auernhammer, C., Caplin, M., Christ, E., Couvelard, A., Herder, W. D., Eriksson, B., Ferone, D., Goretzki, P., Gross, D., Hyrdel, R., Jensen, R., Kaltsas, G., Keleştimur, F., Klöppel, G., Knapp, W., Knigge, U., Komminoth, P., Körner, M., Kos Kudła, B., Krenning, E., Kulke, M., Kvols, L., Manfredi, Riccardo, Mcnicol, A., Niederle, B., Nilsson, O., Öberg, K., O'Connor, J., Pape, U., Pavel, M., Plöckinger, U., Ramage, J., Ricke, J., Rindi, G., Ruszniewski, P., Salazar, R., Scoazec, J., Garcia, M. S., Sundin, A., Vullierme, M., Wiedenmann, B., Wildi, S., Thomas, Steinmüller, Reza, Kianmanesh, Falconi, Massimo, Aldo, Scarpa, Babs, Taal, Dik J., Kwekkeboom, José M., Lope, Aurel, Perren, George, Nikou, James, Yao, Gian Franco, Delle, Dermot, O'Toole, Frascati Consensus, Conference, Radiology & Nuclear Medicine, and Cardiology

Subjects
medicine.medical_specialty, Consensus, ACTING SOMATOSTATIN ANALOG, Endocrinology, Diabetes and Metabolism, Guidelines as Topic, Biology, HEPATIC ARTERIAL CHEMOEMBOLIZATION, Metastasis, Cellular and Molecular Neuroscience, Endocrinology, Internal medicine, Endocrine Gland Neoplasms, medicine, Digestive System, Humans, Liver Neoplasms, Endocrine system, Endocrine gland neoplasm, Endocrine and Autonomic Systems, General surgery, Cancer, Hindgut, Midgut, Foregut, LASER-INDUCED THERMOTHERAPY, medicine.disease, HEPATIC ARTERIAL CHEMOEMBOLIZATION, GASTROENTEROPANCREATIC NEUROENDOCRINE TUMORS, LASER-INDUCED THERMOTHERAPY, ACTING SOMATOSTATIN ANALOG, PORTAL-VEIN EMBOLIZATION, ISLET-CELL CARCINOMA, ISLET-CELL CARCINOMA, PORTAL-VEIN EMBOLIZATION, Unknown primary, GASTROENTEROPANCREATIC NEUROENDOCRINE TUMORS
Abstract

a DRK Kliniken Westend, Berlin , Germany; b UFR Bichat-Beaujon-Louis Mourier, Service de Chirurgie Digestive, Hopital Louis Mourier, Colombes , France; c Medicine and Surgery, General Surgery Section, MED/18 – General Surgery and d Department of Pathology, University of Verona, Verona , Italy; e Netherlands Cancer Centre, Amsterdam , and f Department of Nuclear Medicine, Erasmus University Medical Center, Rotterdam , The Netherlands

Published
2008

29. Consensus guidelines for the management of patients with digestive neuroendocrine tumors - Well-differentiated jejunal-ileal tumor/carcinoma

Author

Eriksson, B., Klöppel, G., Krenning, E., Ahlman, H., Plöckinger, U., Wiedenmann, B., Arnold, R., Auernhammer, C., Körner, M., Rindi, G., Wildi, S., Caplin, M., Fave, G. D., Ferone, D., Goretzki, P., Hyrdel, R., Jensen, R., Kaltsas, G., Keleştimur, F., Kianmanesh, R., Komminoth, P., Kos Kudła, B., Kvols, L., Kwekkeboom, D., Lopes, J., Manfredi, Riccardo, Mcnicol, A., Niederle, B., Nilsson, O., Nikou, G., Öberg, K., O'Connor, J., O'Toole, D., Pavel, M., Perren, A., Ramage, J., Ricke, J., Ruszniewski, P., Scarpa, Aldo, Scoazec, J., Garcia, M. S., Steinmüller, T., Taal, B., Vullierme, M., Yao, J., and Radiology & Nuclear Medicine

Subjects
medicine.medical_specialty, Pathology, Consensus, MIDGUT CARCINOID-TUMORS, ENDOCRINE GASTROENTEROPANCREATIC TUMORS, RECEPTOR-MEDIATED RADIOTHERAPY, RADIOLABELED SOMATOSTATIN ANALOG, RECOMBINANT INTERFERON-ALPHA, RADIONUCLIDE THERAPY, MIDGUT CARCINOID-TUMORS, Endocrinology, Diabetes and Metabolism, RADIONUCLIDE THERAPY, Neuroendocrine tumors, digestive system, RECOMBINANT INTERFERON-ALPHA, Cellular and Molecular Neuroscience, Endocrinology, Internal medicine, Carcinoma, Humans, Medicine, ENDOCRINE GASTROENTEROPANCREATIC TUMORS, Gastrointestinal Neuroendocrine Tumor, RADIOLABELED SOMATOSTATIN ANALOG, Jejunal Neoplasms, Endocrine and Autonomic Systems, business.industry, digestive, oral, and skin physiology, Metastatic carcinoid tumor, Cancer, medicine.disease, Carcinoma, Neuroendocrine, Well differentiated, Ileal Neoplasms, Practice Guidelines as Topic, Radionuclide therapy, Neuroendocrine therapy, business, RECEPTOR-MEDIATED RADIOTHERAPY
Abstract

Consensus guidelines for the management of patients with digestive neuroendocrine tumors : well-differentiated jejunal-ileal tumor/carcinoma

Published
2008
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30. Poorly differentiated carcinomas of the foregut (gastric, duodenal and pancreatic)

Author

Nilsson, O., Cutsem, E. V., Fave, G. D., Yao, J., Pavel, M., Mcnicol, A., Garcia, M. S., Knapp, W., Keleştimur, F., Sauvanet, A., Pauwels, S., Kwekkeboom, D., Caplin, M., Ahlman, H., Arnold, R., Bechstein, W., Cadiot, G., Christ, E., Chung, D., Couvelard, A., Herder, W. D., Eriksson, B., Falchetti, A., Falconi, Massimo, Ferone, D., Goretzki, P., Gross, D., Hochhauser, D., Hyrdel, R., Jensen, R., Kaltsas, G., Kianmanesh, R., Knigge, U., Komminoth, P., Körner, M., Kos Kudła, B., Kvols, L., Lewington, V., Lopes, J., Manfredi, Riccardo, Mitry, E., Niederle, B., Nikou, G., Öberg, K., O'Connor, J., O'Toole, D., Pape, U., Perren, A., Plöckinger, U., Ramage, J., Ricke, J., Rindi, G., Ruszniewski, P., Salazar, R., Scarpa, Aldo, Scoazec, J., Steinmüller, T., Sundin, A., Taal, B., Vullierme, M., Wiedenmann, B., Wildi, S., Zgliczynski, S., Radiology & Nuclear Medicine, O., Nilsson, E. V., Cutsem, G. D., Fave, J., Yao, M., Pavel, A., Mcnicol, M. S., Garcia, W., Knapp, F., Keleştimur, A., Sauvanet, S., Pauwel, D., Kwekkeboom, M., Caplin, and Falconi, M

Subjects
SMALL-CELL-CARCINOMA, NEUROENDOCRINE CARCINOMAS, TUMORS, CHEMOTHERAPY, STOMACH, MANAGEMENT, CISPLATIN, ETOPOSIDE, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Biology, Cellular and Molecular Neuroscience, CISPLATIN, Endocrinology, Duodenal Neoplasms, Stomach Neoplasms, Internal medicine, STOMACH, SMALL-CELL-CARCINOMA, medicine, MANAGEMENT, Humans, ddc:610, Royal infirmary, Endocrine and Autonomic Systems, Poorly differentiated, General surgery, GASTRIC/DUODENAL, Carcinoma, CHEMOTHERAPY, TUMORS, Neuroendocrine Carcinomas, Pancreatic Neoplasms, ETOPOSIDE, NEUROENDOCRINE CARCINOMAS
Abstract

a Department of Pathology, Gothenburg University, Gothenburg , Sweden; b Department of Gastroenterology, Gasthuisberg University, Leuven , Belgium; c Department of Gastroenterology, Ospedale S. Andrea, Rome , Italy; d Department of Oncology, University of Texas, Houston, Tex. , USA; e Department of Endocrinology, Erlangen University, Erlangen , Germany; f Department of Oncology and Pathology, Royal Infirmary Hospital, Glasgow , UK; g Department of Oncology, Virgen de la Victoria Hospital, Malaga , Spain; h Department of Nuclear Medicine, Medizinische Hochschule Hannover, Hannover , Germany; i Department of Endocrinology, Erciyes University, Kayseri , Turkey; j Department of Surgery, Beaujon Hospital, Clichy , France; k Department of Nuclear Medicine, Catholique de Louvain University, Brussels , Belgium; l Department of Nuclear Medicine, Erasmus MC University, Rotterdam , The Netherlands; m Department of Gastroenterology, Royal Free Hospital, London , UK

Published
2006

31. ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms: functional pancreatic endocrine tumor syndromes

Author

Jensen, R. T., Cadiot, G., Brandi, M. L., W. W., De, Kaltsas, G., Komminoth, P., Scoazec, J., Salazar, R., Sauvanet, A., Kianmanesh, R., Conference Anlauf M, B. C., Arnold, R, Bartsch, D, Baudin, E, Baum, R, Brandi, Ml, Cadiot, G, Costa, F, Caplin, M, Couvelard, A, de Herder, W, Delle Fave, G, Denecke, T, Eriksson, B, Falconi, Massimo, Gress, T, Gross, D, Grossman, A, Jensen, R, Kaltsas, G, Kelestimur, F, Kianmanesh, R, Klöppel, G, Klose, Kj, Knigge, U, Komminoth, P, Kos Kudla, B, Krenning, E, Kwekkeboom, D, Lopes, Jm, Niederle, B, Nilsson, O, Öberg, K, O'Connor, J, O'Toole, D, Pape, Uf, Papotti, M, Pascher, A, Pavel, M, Perren, A, Plöckinger, U, Rindi, G, Ruszniewski, P, Salazar, R, Sasano, H, Sauvanet, A, Scoazec, Jy, Steinmüller, T, Sundin, A, Taal, B, Tomassetti, P, Van Cutsem, E, Vullierme, Mp, Wiedenmann, B., R. T., Jensen, G., Cadiot, M. L., Brandi, W. W., De, G., Kaltsa, P., Komminoth, J., Scoazec, R., Salazar, A., Sauvanet, R., Kianmanesh, B. C., Conference Anlauf M, Arnold, R, Bartsch, D, Baudin, E, Baum, R, Brandi, Ml, Cadiot, G, Costa, F, Caplin, M, Couvelard, A, de Herder, W, Delle Fave, G, Denecke, T, Eriksson, B, Falconi, Massimo, Gress, T, Gross, D, Grossman, A, Jensen, R, Kaltsas, G, Kelestimur, F, Kianmanesh, R, Klöppel, G, Klose, Kj, Knigge, U, Komminoth, P, Kos Kudla, B, Krenning, E, Kwekkeboom, D, Lopes, Jm, Niederle, B, Nilsson, O, Öberg, K, O'Connor, J, O'Toole, D, Pape, Uf, Papotti, M, Pascher, A, Pavel, M, Perren, A, Plöckinger, U, Rindi, G, Ruszniewski, P, Salazar, R, Sasano, H, Sauvanet, A, Scoazec, Jy, Steinmüller, T, Sundin, A, Taal, B, Tomassetti, P, Van Cutsem, E, Vullierme, Mp, Wiedenmann, B., and Internal Medicine

Subjects
ENETS Consensus Guidelines, medicine.medical_specialty, Pathology, Endocrinology, Diabetes and Metabolism, ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms: functional pancreatic endocrine tumor syndromes, Hypoglycemia, Neuroendocrine tumors, Cellular and Molecular Neuroscience, Endocrinology, Internal medicine, medicine, Humans, Pancreatic polypeptide, MEN1, Multiple endocrine neoplasia, biology, Endocrine and Autonomic Systems, business.industry, Chromogranin A, medicine.disease, Pancreatic Neoplasms, Neuroendocrine Tumors, medicine.anatomical_structure, biology.protein, Pancreas, business, Carcinoid syndrome
Abstract

Pancreatic endocrine tumors (p-NETs) include both pancreatic neuroendocrine tumors (p-NETs) associated with a functional syndrome (functional p-NETs) or those associated with no distinct clinical syndrome (non-functional p-NETs) [1,2,3,4]. Non-functional p-NETs frequently secrete pancreatic polypeptide, chromogranin A, neuron-specific enolase, human chorionic gonadotrophin subunits, calcitonin, neurotensin or other peptides, but they do not usually produce specific symptoms and thus are considered clinically to be non-functional tumors [2,3,5,6,7]. Only the functional p-NETs will be considered in this section. The two most common functional p-NETs (gastrinomas, insulinomas) are considered separately, whereas the other well-described and possible rare functional p-NETs are considered together as a group called rare functional p-NETs (RFTs) (table ​(table1)1) [1,2,3,4]. Table 1 Functional pancreatic endocrine tumor (PET) syndromes Gastrinomas are neuroendocrine neoplasms, usually located in the duodenum or pancreas, that secrete gastrin and cause a clinical syndrome known as Zollinger-Ellison syndrome (ZES). ZES is characterized by gastric acid hypersecretion resulting in severe peptic disease (peptic ulcer disease (PUD), gastroesophageal reflux disease (GERD)) [8,9,10]. In this section, ZES due to both duodenal and pancreatic gastrinomas will be covered together because clinically they are similar [8,10]. Specific points related to gastrinomas associated with the genetic syndrome of Multiple Endocrine Neoplasia type 1 (MEN1) (25% of cases) will also be mentioned [11,12]. Insulinomas are neuroendocrine neoplasms located in the pancreas that secrete insulin, which causes a distinct syndrome characterized by symptoms due to hypoglycemia [2,13,14,15]. The symptoms are typically associated with fasting and the majority of patients have symptoms secondary to hypoglycemic central nervous system (CNS) effects (headaches, confusion, visual disturbances, etc.) or due to catecholamine excess secondary to hypoglycemia (sweating, tremor, palpitations, etc.) [2,3,13,14,15]. RFTs can occur in the pancreas or in other locations (VIPomas, somatostatinomas, GRHomas, ACTHomas, p-NETs causing carcinoid syndrome or hypercalcemia (PTHrp-omas)) (table ​(table1)1) [1,2,3,4,5,7]. Each of the established RFT syndromes is associated with a distinct clinical syndrome reflecting the actions of the ectopically secreted hormone. Other RFTs are listed as causing a possible specific syndrome either because there are too few cases or there is disagreement about whether the described features are actually a distinct syndrome (table ​(table1)1) [1,2,3,4,5,7].

Published
2012

32. ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Neoplasms: Colorectal Neuroendocrine Neoplasms

Author

M. Caplin, A. Sundin, O. Nillson, R. P. Baum, K. J. Klose, F. Kelestimur, U. Plöckinger, M. Papotti, R. Salazar, A. Pascher, B. C. Conference Anlauf M, Arnold R, Bartsch D, Baudin E, Baum R, Brandi ML, Cadiot G, Costa F, Caplin M, Couvelard A, de Herder W, Delle Fave G, Denecke T, Eriksson B, Gress T, Gross D, Grossman A, Jensen R, Kaltsas G, Kelestimur F, Kianmanesh R, Klöppel G, Klose KJ, Knigge U, Komminoth P, Kos Kudla B, Krenning E, Kwekkeboom D, Lopes JM, Niederle B, Nilsson O, Öberg K, O'Connor J, O'Toole D, Pape UF, Papotti M, Pascher A, Pavel M, Perren A, Plöckinger U, Rindi G, Ruszniewski P, Salazar R, Sasano H, Sauvanet A, Scoazec JY, Steinmüller T, Sundin A, Taal B, Tomassetti P, Van Cutsem E, Vullierme MP, Wiedenmann B., FALCONI , MASSIMO, M., Caplin, A., Sundin, O., Nillson, R. P., Baum, K. J., Klose, F., Kelestimur, U., Plöckinger, M., Papotti, R., Salazar, A., Pascher, B. C., Conference Anlauf M, Arnold, R, Bartsch, D, Baudin, E, Baum, R, Brandi, Ml, Cadiot, G, Costa, F, Caplin, M, Couvelard, A, de Herder, W, Delle Fave, G, Denecke, T, Eriksson, B, Falconi, Massimo, Gress, T, Gross, D, Grossman, A, Jensen, R, Kaltsas, G, Kelestimur, F, Kianmanesh, R, Klöppel, G, Klose, Kj, Knigge, U, Komminoth, P, Kos Kudla, B, Krenning, E, Kwekkeboom, D, Lopes, Jm, Niederle, B, Nilsson, O, Öberg, K, O'Connor, J, O'Toole, D, Pape, Uf, Papotti, M, Pascher, A, Pavel, M, Perren, A, Plöckinger, U, Rindi, G, Ruszniewski, P, Salazar, R, Sasano, H, Sauvanet, A, Scoazec, Jy, Steinmüller, T, Sundin, A, Taal, B, Tomassetti, P, Van Cutsem, E, Vullierme, Mp, and Wiedenmann, B.

Subjects
medicine.medical_specialty, Endocrine and Autonomic Systems, business.industry, Endocrinology, Diabetes and Metabolism, ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms: colorectal neuroendocrine neoplasms, stomatognathic diseases, Cellular and Molecular Neuroscience, Neuroendocrine Tumors, Endocrinology, Internal medicine, medicine, Humans, business, Colorectal Neoplasms
Abstract

ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms : colorectal neuroendocrine neoplasms

Published
2012

33. Medical Therapy of Acromegaly

Author

Plöckinger, U.

Subjects
Article Subject
Abstract

This paper outlines the present status of medical therapy of acromegaly. Indications for permanent postoperative treatment, postirradiation treamtent to bridge the interval until remission as well as primary medical therapy are elaborated. Therapeutic efficacy of the different available drugs—somatostatin receptor ligands (SRLs), dopamine agonists, and the GH antagonist Pegvisomant—is discussed, as are the indications for and efficacy of their respective combinations. Information on their mechanism of action, and some pharmakokinetic data are included. Special emphasis is given to the difficulties to define remission criteria of acromegaly due to technical assay problems. An algorithm for medical therapy in acromegaly is provided.

Published
2012
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34. ENETS Consensus Guidelines for the management of patients with gastroduodenal neoplasms

Author

Fave, G. D., Kwekkeboom, D. J., Cutsem, E. V., Rindi, G., Kos Kudla, B., Knigge, U., Sasano, H., Tomassetti, P., Salazar, R., Ruszniewski, P., Conference Anlauf M, B. C., Arnold, R, Bartsch, D, Baudin, E, Baum, R, Brandi, Ml, Cadiot, G, Costa, F, Caplin, M, Couvelard, A, de Herder, W, Delle Fave, G, Denecke, T, Eriksson, B, Falconi, Massimo, Gress, T, Gross, D, Grossman, A, Jensen, R, Kaltsas, G, Kelestimur, F, Kianmanesh, R, Klöppel, G, Klose, Kj, Knigge, U, Komminoth, P, Kos Kudla, B, Krenning, E, Kwekkeboom, D, Lopes, Jm, Niederle, B, Nilsson, O, Öberg, K, O'Connor, J, O'Toole, D, Pape, Uf, Papotti, M, Pascher, A, Pavel, M, Perren, A, Plöckinger, U, Rindi, G, Ruszniewski, P, Salazar, R, Sasano, H, Sauvanet, A, Scoazec, Jy, Steinmüller, T, Sundin, A, Taal, B, Tomassetti, P, Van Cutsem, E, Vullierme, Mp, Wiedenmann, B., Fave, G. D., Kwekkeboom, D. J., Cutsem, E. V., Rindi, G., Kos Kudla, B., Knigge, U., Sasano, H., Tomassetti, P., Salazar, R., Ruszniewski, P., Radiology & Nuclear Medicine, Delle Fave G., Kwekkeboom DJ., Van Cutsem E., Rindi G., Kos-Kudla B., Knigge U., Sasano H., Tomassetti P., Salazar R., and Ruszniewski P.

Subjects
medicine.medical_specialty, Settore MED/06 - ONCOLOGIA MEDICA, Endocrine and Autonomic Systems, business.industry, Endocrinology, Diabetes and Metabolism, MEDLINE, diagnosis/epidemiology/therapy, GUIDELINES, University hospital, ENETS Consensus Guidelines for the management of patients with gastroduodenal neoplasms, Cellular and Molecular Neuroscience, Neuroendocrine Tumors, Endocrinology, Duodenal Neoplasms, diagnosis/epidemiology/therapy, Humans, Neuroendocrine Tumors, diagnosis/epidemiology/therapy, Stomach Neoplasms, Stomach Neoplasms, Internal medicine, medicine, Humans, business
Abstract

a Department of Digestive and Liver Disease, Ospedale Sant’Andrea, Rome , Italy; b Department of Oncology, Royal Free University UFR Bichat-Beaujon-Louis Mourier, Colombes , France; c Digestive Oncology, University Hospital Gasthuisberg/Leuven, Leuven , Belgium; d Institute of Pathology, Catholic University – Policlinic A. Gemelli, Rome , Italy; e Department of Endocrinology, Medical University of Silesia, Katowice , Poland; f Department of Surgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen , Denmark; g Department of Pathology, Tohoku University Graduate School of Medicine, Sendai , Japan; h Department of Internal Medicine and Gastroenterology, St. Orsola Hospital, University of Bologna, Bologna , Italy; i Institut Catala d’Oncologia (IDIBELL), Barcelona , Spain; j Department of Gastroenterology, Beaujon Hospital, Clichy , France

Published
2012

37. ENETS consensus guidelines for the management of bone and lung metastases from neuroendocrine tumors

Author

Kos Kudła, B, O'Toole, D, Falconi, Massimo, Gross, D, Klöppel, G, Sundin, A, Ramage, J, Oberg, K, Wiedenmann, B, Komminoth, P, Van Custem, E, Mallath, M, Papotti, M, Caplin, M, Arnold R, Palma de Mallorca Consensus Conference P. a. r. t. i. c. i. p. a. n. t. s., Buscombe, J, Chen, Yj, Cioppi, F, de Herder, W, Eriksson, B, Fazio, N, Grossman, A, Kaltsas, G, Kianmanesh, R, Kulke, M, Kwekkeboom, D, Lebtahi, R, Lesurtel, M, Lind, P, Lopes, Jm, Nilsson, O, O'Connor, J, Pape, Uf, Pavel, M, Perren, A, Plöckinger, U, Rindi, G, Ruszniewski, P, Sasano, H, Scoazec, Jy, Sevilla Garcia, I, Steinmüller, T., Kos Kudła, B, O'Toole, D, Falconi, Massimo, Gross, D, Klöppel, G, Sundin, A, Ramage, J, Oberg, K, Wiedenmann, B, Komminoth, P, Van Custem, E, Mallath, M, Papotti, M, and Caplin, M.

Subjects
medicine.medical_specialty, Pathology, Lung Neoplasms, Endocrinology, Diabetes and Metabolism, Lung metastasis, MEDLINE, Bone Neoplasms, Digestive System Neoplasms, Humans, Neuroendocrine Tumors, Neuroendocrine tumors, Cellular and Molecular Neuroscience, Endocrinology, Internal medicine, medicine, Lung, Endocrine and Autonomic Systems, business.industry, Respiratory disease, Cancer, respiratory system, medicine.disease, respiratory tract diseases, medicine.anatomical_structure, Lung disease, business
Abstract

ENETS consensus guidelines for the management of bone and lung metastases from neuroendocrine tumors

Published
2010

38. ENETS consensus guidelines for the management of brain, cardiac and ovarian metastases from neuroendocrine tumors

Author

Pavel, M, Grossman, A, Arnold, R, Perren, A, Kaltsas, G, Steinmüller, T, de Herder, W, Nikou, G, Plöckinger, U, Lopes, Jm, Sasano, H, Buscombe, J, Lind, P, O'Toole, D, Oberg, K, Collaborators: Caplin M, Palma de Mallorca Consensus Conference P. a. r. t. i. c. i. p. a. n. t. s., Chen, Yj, Cioppi, F, Eriksson, B, Falconi, M, Fazio, N, Gross, D, Kianmanesh, R, Komminoth, Gp, Kos Kudła, B, Kulke, M, Kwekkeboom, D, Lebtahi, R, Lesurtel, M, Mallath, M, Nilsson, O, O'Connor, J, Pape, Uf, Papotti, Mauro Giulio, Ramage, J, Rindi, G, Ruszniewski, P, Scoazec, Jy, Sevilla Garcia, I, Sundin, A, Van Cutsem, E, Wiedenmann, B., Erasmus MC other, Internal Medicine, M, Pavel, A., Grossman, R., Arnold, A., Perren, G., Kaltsa, T., Steinmüller, W. d., Herder, G., Nikou, U., Plöckinger, J. M., Lope, H., Sasano, J., Buscombe, P., Lind, D., O'Toole, K., Oberg, and Falconi, Massimo

Subjects
endocrine system, medicine.medical_specialty, Pathology, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Brain Neoplasms, Digestive System Neoplasms, Female, Heart Neoplasms, Humans, Neuroendocrine Tumors, Ovarian Neoplasms, Ovary, Neuroendocrine tumors, Metastasis, Cellular and Molecular Neuroscience, Heart neoplasms, Endocrinology, Internal medicine, medicine, Endocrine and Autonomic Systems, business.industry, Cancer, medicine.disease, female genital diseases and pregnancy complications, ddc, medicine.anatomical_structure, cardiovascular system, business
Abstract

ENETS consensus guidelines for the management of brain, cardiac and ovarian metastases from neuroendocrine tumors

Published
2010
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39. ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Towards a Standardized Approach to the Diagnosis of Gastroenteropancreatic Neuroendocrine Tumors and Their Prognostic Stratification

Author

Klöppel, G., Couvelard, A., Perren, A., Komminoth, P., Mcnicol, A., Nilsson, O., Scarpa, Aldo, Scoazec, J., Wiedenmann, B., Papotti, M., Rindi, G., Plöckinger, U., Akerström, G, Annibale, B, Arnold, R, Bajetta, E, Barkmanova, J, Chen, Yj, Costa, F, Davar, J, de Herder, W, Delle Fave, G, Eriksson, B, Falconi, Massimo, Ferone, D, Gross, D, Grossman, A, Gustafsson, B, Hyrdel, R, Ivan, D, Kaltsas, G, Kianmanesh, R, Knigge, Up, Kos Kudła, B, Kwekkeboom, D, Lebtahi, R, Lewington, V, Mitry, E, Oberg, K, O'Connor, J, O'Toole, D, Pape, Uf, Pavel, M, Perren, A, Platania, M, Rindi, G, Ruszniewski, P, Salazar, R, Scheidhauer, K, Sundin, A, Szpak, W, Taal, B, Vitek, P, Vullierme, M. P., G., Klöppel, A., Couvelard, A., Perren, P., Komminoth, A., Mcnicol, O., Nilsson, A., Scarpa, J., Scoazec, B., Wiedenmann, M., Papotti, G., Rindi, U., Plöckinger, Akerström, G, Annibale, B, Arnold, R, Bajetta, E, Barkmanova, J, Chen, Yj, Costa, F, Davar, J, de Herder, W, Delle Fave, G, Eriksson, B, Falconi, Massimo, Ferone, D, Gross, D, Grossman, A, Gustafsson, B, Hyrdel, R, Ivan, D, Kaltsas, G, Kianmanesh, R, Knigge, Up, Kos Kudła, B, Kwekkeboom, D, Lebtahi, R, Lewington, V, Mitry, E, Oberg, K, O'Connor, J, O'Toole, D, Pape, Uf, Pavel, M, Perren, A, Platania, M, Rindi, G, Ruszniewski, P, Salazar, R, Scheidhauer, K, Sundin, A, Szpak, W, Taal, B, Vitek, P, and Vullierme, M. P.

Subjects
Oncology, Lymphatic metastasis, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, 610 Medicine & health, Adenocarcinoma, Neuroendocrine tumors, Prognostic stratification, Cellular and Molecular Neuroscience, Endocrinology, Stomach Neoplasms, Internal medicine, medicine, Humans, Neoplasm Staging, Endocrine and Autonomic Systems, business.industry, Standardized approach, Disease classification, Biological Markers, Lymphatic Metastasis, Neuroendocrine Tumors, Pancreatic Neoplasms, Prognosis, medicine.disease, ddc, Cancer registry, 570 Life sciences, biology, Neoplasm staging, business, Biomarkers
Abstract

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors : towards a standardized approach to the diagnosis of gastroenteropancreatic neuroendocrine tumors and their prognostic stratification

Published
2009
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41. ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: pre- and perioperative therapy in patients with neuroendocrine tumors

Author

Akerström, G., Falconi, M., Kianmanesh, R., Ruszniewski, P., Plöckinger, U., Annibale, B., Arnold, R., Bajetta, E., Barkmanova, J., Chen, Y. J., Costa, F., Couvelard, A., Davar, J., Herder, W. D., Fave, G. D., Eriksson, B., Ferone, D., Gross, D., Grossman, A., Gustafsson, B., Hyrdel, R., Ivan, D., Kaltsas, G., Klöppel, G., Knigge, U. P., Komminoth, P., Kos Kudla, B., Kwekkeboom, D., Lebtahi, R., Lewington, V., Mcnicol, A. M., Mitry, E., Nilsson, O., Öberg, K., O'Connor, J., O'Toole, D., Pape, U. F., Papotti, M., Pavel, M., Perren, A., Platania, M., Rindi, G., Salazar, R., Scarpa, Aldo, Scheidhauer, K., Scoazec, J. Y., Sundin, A., Szpak, W., Taal, B., Vitek, P., Vullierme, M. P., Wiedenmann, B., G., Akerström, Falconi, Massimo, R., Kianmanesh, P., Ruszniewski, U., Plöckinger, and Mallorca Consensus Conference, Participants

Subjects
glucagonoma, Endocrinology, Diabetes and Metabolism, perioperative period, carcinoid syndrome, Haemophilus infection, somatostatin derivative, anesthesia, insulinoma, Small, Cellular and Molecular Neuroscience, Endocrinology, Stomach Neoplasms, cancer diagnosis, Intestinal Neoplasms, Intestine, Small, Preoperative Care, Humans, electrolyte disturbance, Intestine, Neuroendocrine Tumors, Pancreas, Pancreatic Neoplasms, Postoperative Care, Stomach, human, conference paper, vipoma, gastrinoma, Endocrine and Autonomic Systems, practice guideline, diazoxide, Pneumococcus vaccine, preoperative evaluation, hypoglycemia, priority journal, octreotide, neuroendocrine tumor, preoperative care
Published
2009

44. Well-differenitated duodenal tumor/carcinoma(excluding gastrinomas)

Author

Jensen, R., Rindi, G., Arnold, R., Lopes, J., Brandi, M., Bechstein, W., Christ, E., Taal, B., Knigge, U., Ahlman, H., Kwekkeboom, D., O'Toole, D., Cadiot, G., Caplin, M., Chung, D., Couvelard, A., Herder, W. D., Fave, G. D., Eriksson, B., Falchetti, A., Falconi, Massimo, Ferone, D., Goretzki, P., Gross, D., Hochhauser, D., Hyrdel, R., Kaltsas, G., Keleştimur, F., Kianmanesh, R., Knapp, W., Komminoth, P., Körner, M., Kos Kudła, B., Kvols, L., Lewington, V., Manfredi, Riccardo, Mcnicol, A., Mitry, E., Niederle, B., Nikou, G., Nilsson, O., Öberg, K., O'Connor, J., Pauwels, S., Pape, U., Pavel, M., Perren, A., Plöckinger, U., Ramage, J., Ricke, J., Ruszniewski, P., Salazar, R., Sauvanet, A., Scarpa, Aldo, Scoazec, J., Garcia, M. S., Steinmüller, T., Sundin, A., Cutsem, E. V., Vullierme, M., Wiedenmann, B., Wildi, S., Yao, J., Zgliczynski, S., Radiology & Nuclear Medicine, R., Jensen, G., Rindi, R., Arnold, J., Lope, M., Brandi, W., Bechstein, E., Christ, B., Taal, U., Knigge, H., Ahlman, D., Kwekkeboom, D., O'Toole, G., Cadiot, M., Caplin, D., Chung, A., Couvelard, W. D., Herder, G. D., Fave, B., Eriksson, A., Falchetti, Falconi, Massimo, D., Ferone, P., Goretzki, D., Gro, D., Hochhauser, R., Hyrdel, G., Kaltsa, F., Keleştimur, R., Kianmanesh, W., Knapp, P., Komminoth, M., Körner, B., Kos Kudła, L., Kvol, V., Lewington, R., Manfredi, A., Mcnicol, E., Mitry, B., Niederle, G., Nikou, O., Nilsson, K., Öberg, J., O'Connor, S., Pauwel, U., Pape, M., Pavel, A., Perren, U., Plöckinger, J., Ramage, J., Ricke, P., Ruszniewski, R., Salazar, A., Sauvanet, A., Scarpa, J., Scoazec, M. S., Garcia, T., Steinmüller, A., Sundin, E. V., Cutsem, M., Vullierme, B., Wiedenmann, S., Wildi, J., Yao, and S., Zgliczynski

Subjects
ENDOCRINE GASTROENTEROPANCREATIC TUMORS, medicine.medical_specialty, Somatostatin receptor scintigraphy, Endocrine and Autonomic Systems, business.industry, Endocrinology, Diabetes and Metabolism, General surgery, Carcinoma, ZOLLINGER-ELLISON-SYNDROME, Well differentiated, Cellular and Molecular Neuroscience, Endocrinology, Duodenal Neoplasms, Internal medicine, Duodenal Tumor, Cancer centre, medicine, AMPULLARY CARCINOID-TUMORS, Humans, ZOLLINGER-ELLISON-SYNDROME, SOMATOSTATIN RECEPTOR SCINTIGRAPHY, ENDOCRINE GASTROENTEROPANCREATIC TUMORS, AMPULLARY CARCINOID-TUMORS, business, SOMATOSTATIN RECEPTOR SCINTIGRAPHY
Abstract

a Digestive Diseases Branch, NIDDK, NIH, Bethesda, Md. , USA; b Dipartimento di Patologia e Medicina di Laboratorio, Universita di Parma, Parma , Italy; c Division of Gastroenterology and Endocrinology, Department of Internal Medicine, Philipps University, Marburg , Germany; d Department of Pathology, IPATIMUP Hospital, Porto , Portugal; e Dipartimento di Fisiopatologia Clinica, Universita di Firenze, Firenze , Italy; f Department of Surgery, Johann-Wolfgang-Goethe-Universitat, Frankfurt , Germany; g E. Christ, Department of Endocrinology, Inselspital, Bern , Switzerland; h Department of Oncology, Netherlands Cancer Centre, Amsterdam , The Netherlands; i Department of Surgery, Rigshospitalet Blegdamsvej Hospital, Copenhagen , Denmark; j Department of Surgery, Gothenburg University, Gothenburg , Sweden; k Department of Nuclear Medicine, Erasmus Medical Center, Rotterdam , The Netherlands; l Service de Gastroenterologie-Pancreatologie, Pole des Maladies de l’Appareil Digestif, Hopital Beaujon, Clichy , France

Published
2006

45. Well-differentiated pancreatic tumor/carcinoma: Insulinoma

Author

Herder, W. D., Niederle, B., Scoazec, J., Pauwels, S., Klöppel, G., Falconi, Massimo, Kwekkeboom, D., Öberg, K., Eriksson, B., Wiedenmann, B., Rindi, G., O'Toole, D., Ferone, D., Ahlman, H., Arnold, R., Bechstein, W., Cadiot, G., Caplin, M., Christ, E., Chung, D., Couvelard, A., Fave, G. D., Falchetti, A., Goretzki, P., Gross, D., Hochhauser, D., Hyrdel, R., Jensen, R., Kaltsas, G., Keleştimur, F., Kianmanesh, R., Knapp, W., Knigge, U., Komminoth, P., Körner, M., Kos Kudła, B., Kvols, L., Lewington, V., Lopes, J., Manfredi, Riccardo, Mcnicol, A., Mitry, E., Nikou, G., Nilsson, O., O'Connor, J., Pape, U., Pavel, M., Perren, A., Plöckinger, U., Ramage, J., Ricke, J., Ruszniewski, P., Salazar, R., Sauvanet, A., Scarpa, Aldo, Garcia, M. S., Steinmüller, T., Sundin, A., Taal, B., Cutsem, E. V., Vullierme, M., Wildi, S., Yao, J., Zgliczyñski, S., W. W., de Herder, B., Niederle, J., Scoazec, S., Pauwel, G., Kloppel, Falconi, Massimo, D. J., Kwekkeboom, K., Oberg, B., Eriksson, B., Wiedenmann, G., Rindi, D., O'Toole, D., Ferone, F. C., Conference, E. N., Tumor Society, Internal Medicine, and Gastroenterology & Hepatology

Subjects
medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Intraoperative ultrasound, Carcinoma pancreas, Cellular and Molecular Neuroscience, Endocrinology, OCTREOTIDE, Internal medicine, medicine, ENDOSCOPIC ULTRASOUND, Humans, Carcinoma, Insulinoma, Pancreatic Neoplasms, Pancreas Carcinoma, Somatostatin receptor scintigraphy, SLET-CELL TUMORS, Endocrine and Autonomic Systems, business.industry, General surgery, HYPERINSULINEMIC HYPOGLYCEMIA, LOCALIZATION, University hospital, Well differentiated, SLET-CELL TUMORS, SOMATOSTATIN RECEPTOR SCINTIGRAPHY, NEUROENDOCRINE TUMORS, HYPERINSULINEMIC HYPOGLYCEMIA, INTRAOPERATIVE ULTRASOUND, ENDOSCOPIC ULTRASOUND, ENDOCRINE TUMORS, LOCALIZATION, OCTREOTIDE, MRI, ENDOCRINE TUMORS, INTRAOPERATIVE ULTRASOUND, business, SOMATOSTATIN RECEPTOR SCINTIGRAPHY, NEUROENDOCRINE TUMORS, MRI
Abstract

a Department of Internal Medicine, Section of Endocrinology, Erasmus MC, Rotterdam, The Netherlands; b Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna , Austria; c Hospices Civils de Lyon, Hopital Edouard-Herriot Service Central d‘Anatomie et Cytologie Pathologiques, Lyon , France; d Centre de Medecine Nucleaire, Universite Catholique de Louvain, Brussels , Belgium; e Department of Pathology, University of Kiel, Kiel , Germany; f B Unit of Surgery, Department of Surgery, University of Verona, Verona , Italy; g Department of Nuclear Medicine, Erasmus MC, Rotterdam , The Netherlands; h Department of Endocrine Oncology, University Hospital, Uppsala , Sweden; i Department of Internal Medicine, Division of Hepatology and Gastroenterology, Interdisciplinary Center of Metabolism and Endocrinology, Charite, Campus Virchow Hospital, University for Medicine Berlin, Berlin , Germany; j Service de Gastroenterologie-Pancreatologie, Pole des Maladies de l‘Appareil Digestif, Hopital Beaujon, Clichy , France; k Department of Pathology and Laboratory Medicine, Universita degli Studi, Parma, Italy; l Department of Endocrinology, Genoa University, Genoa , Italy

Published
2006

46. Transient pregnancy-induced Cushing's Syndrome with Aberrant Adrenal hCG receptor

Author

Plöckinger, U, primary, Tiling, N, additional, Blankenstein, O, additional, Weizsäcker, K von, additional, Allolio, B, additional, Kroiss, M, additional, Hauptmann, K, additional, Saeger, W, additional, Radke, C, additional, Steinmüller, T, additional, Rahman, N, additional, Chrusciel, M, additional, Doroszko, M, additional, Lacroix, A, additional, Huhtaniemi, I, additional, and Quinkler, M, additional

Published
2014
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48. ENETS consensus guidelines for the standards of care in neuroendocrine tumors: Biochemical markers

Author

O'Toole, D. (Dermot), Grossman, A. (Ashley Barry), Gross, D. (David), Delle Fave, G. (Gianfranco), Barkmanova, J. (Jaroslava), O'Connor, J. (Juan Manuel), Pape, U.F. (Ulrich Frank), Plöckinger, U. (Ursula), Annibale, B. (Bruno), Arnold, R. (Rudolf), Bajetta, E. (Emilio), Chen, Y.J. (Yuan Jia), Costa, F.P. (Frederico), Couvelard, A. (Anne), Davar, J. (Joseph), Herder, W.W. (Wouter) de, Eriksson, B. (Barbro), Falconi, M. (Massimo), Ferone, D. (Diego), Gustafsson, B.I. (Björn), Hyrdel, R. (Rudolf), Ivan, D. (Diana), Kaltsas, G. (Gregory), Kianmanesh, R. (Reza), Kloppel, G. (Günter), Knigge, U.P. (Ulrich Peter), Komminoth, P. (Paul), Kos-Kudla, B. (Beata), Kwekkeboom, D.J. (Dirk Jan), Lebtahi, R. (Rachida), Lewington, V. (Val), McNicol, A.M. (Anne Marie), Mitry, E. (Emmanuel), Nilsson, O. (Ola), Öberg, K. (Kjell), Papotti, M. (Mauro), Pavel, M. (Marianne), Perren, A. (Aurel), Platania, M. (Marco), Rindi, G. (Guido), Ruszniewski, P. (Philippe), Salazar, R. (Ramon), Scarpa, A. (Aldo), Scheidhauer, K. (Klemens), Scoazec, J.Y. (Jean Yves), Sundin, A. (Anders), Szpak, W. (Waldemar), Taal, B. (Babs), Vitek, P. (Pavel), Vullierme, M.P. (Marie Pierre), Wiedenmann, B. (Bertram), O'Toole, D. (Dermot), Grossman, A. (Ashley Barry), Gross, D. (David), Delle Fave, G. (Gianfranco), Barkmanova, J. (Jaroslava), O'Connor, J. (Juan Manuel), Pape, U.F. (Ulrich Frank), Plöckinger, U. (Ursula), Annibale, B. (Bruno), Arnold, R. (Rudolf), Bajetta, E. (Emilio), Chen, Y.J. (Yuan Jia), Costa, F.P. (Frederico), Couvelard, A. (Anne), Davar, J. (Joseph), Herder, W.W. (Wouter) de, Eriksson, B. (Barbro), Falconi, M. (Massimo), Ferone, D. (Diego), Gustafsson, B.I. (Björn), Hyrdel, R. (Rudolf), Ivan, D. (Diana), Kaltsas, G. (Gregory), Kianmanesh, R. (Reza), Kloppel, G. (Günter), Knigge, U.P. (Ulrich Peter), Komminoth, P. (Paul), Kos-Kudla, B. (Beata), Kwekkeboom, D.J. (Dirk Jan), Lebtahi, R. (Rachida), Lewington, V. (Val), McNicol, A.M. (Anne Marie), Mitry, E. (Emmanuel), Nilsson, O. (Ola), Öberg, K. (Kjell), Papotti, M. (Mauro), Pavel, M. (Marianne), Perren, A. (Aurel), Platania, M. (Marco), Rindi, G. (Guido), Ruszniewski, P. (Philippe), Salazar, R. (Ramon), Scarpa, A. (Aldo), Scheidhauer, K. (Klemens), Scoazec, J.Y. (Jean Yves), Sundin, A. (Anders), Szpak, W. (Waldemar), Taal, B. (Babs), Vitek, P. (Pavel), Vullierme, M.P. (Marie Pierre), and Wiedenmann, B. (Bertram)

Published
2009
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49. Growth hormone dose in growth hormone-deficient adults is not associated with IGF-1 gene polymorphisms

Author

Meyer, S. (Silke), Schaefer, S. (Stephan), Ivan, D. (Diana), Stolk, L. (Lisette), Arp, P.P. (Pascal), Uitterlinden, A.G. (André), Nawroth, P.P. (Peter), Plöckinger, U. (Ursula), Stalla, G.K. (Günter), Tuschy, U. (Ulrich), Weber, M.M. (Matthias), Weise, W.J. (Wolfgang), Pfützner, A. (Andreas), Kann, P. (Peter), Meyer, S. (Silke), Schaefer, S. (Stephan), Ivan, D. (Diana), Stolk, L. (Lisette), Arp, P.P. (Pascal), Uitterlinden, A.G. (André), Nawroth, P.P. (Peter), Plöckinger, U. (Ursula), Stalla, G.K. (Günter), Tuschy, U. (Ulrich), Weber, M.M. (Matthias), Weise, W.J. (Wolfgang), Pfützner, A. (Andreas), and Kann, P. (Peter)

Abstract

Aims: Several SNPs and a microsatellite cytosine-adenine repeat promoter polymorphisms of the IGF-1 gene have been reported to be associated with circulating IGF-1 serum concentrations. Variance in IGF-1 concentrations due to genetic variations may affect different response to growth hormone (GH) treatment, resulting in different individually required GH-doses in GH-defecient patients. The aim of this study was to test if the IGF-1 gene polymorphisms are associated with the GH-dose of GH-defecient adults. Materials & methods: A total of nine SNPs, five addtionally selected SNPs and a cytosine-adenine repeat polymorphism were determined in 133 German adult patients (66 men, 67 women; mean age 45.4 years ± 13.1 stamdard deviation; majority Caucasian) with GH-deficiency (GHD) of different origin, derived from the prospective Pfizer International Metabolic Study (KIMS) Pharmacogenetics Study. Patients received GH-treatment for 12 months with finished dose-titration of GH and centralized IGF-1 measurements. GH-dose after 1 year of treatment, IGF-1 concentrations, IGF-1-standard deviation score (SDS), the IGF-1:GH ratio and anthropometric data were analyzed by genotyped. Results: Except for rs1019731, which showed a significant difference of IGF-1-SDS by genotypes (p=0.02), all polymorphisms showed no associations with the GH-doses, IGF-1 concentrations, IGF-1-SDS and IGF-1:GH ration after adjusting for the confounding variable

Published
2009
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