27 results on '"Pitts, Jared"'
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2. Mechanism and spectrum of inhibition of a 4′-cyano modified nucleotide analog against diverse RNA polymerases of prototypic respiratory RNA viruses
3. Intravenous delivery of GS-441524 is efficacious in the African green monkey model of SARS-CoV-2 infection
4. Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice
5. Mechanism and spectrum of inhibition of a 4′-cyano modified nucleotide analog against diverse RNA polymerases of prototypic respiratory RNA viruses
6. Discovery of GS-7682, a Novel 4′-Cyano-Modified C‑Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys.
7. 539. Efficacy in Multiple SARS-CoV-2 Animal Models Supports Phase 3 Dose Selection for Obeldesivir
8. Antiviral activity of N-(4-hydroxyphenyl) retinamide (4-HPR) against Zika virus
9. Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys
10. Anellovirus Structure Reveals a Mechanism for Immune Evasion
11. Remdesivir and GS-441524 Retain Antiviral Activity against Delta, Omicron, and Other Emergent SARS-CoV-2 Variants
12. Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection
13. Key Metabolic Enzymes Involved in Remdesivir Activation in Human Lung Cells
14. Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosineC-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV
15. Identification of small molecule inhibitors targeting the Zika virus envelope protein
16. Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice
17. Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice
18. Identification of Buffer Conditions for Optimal Thermostability and Solubility of Herpesviral Protein UL37 Using the Thermofluor Assay
19. Small Molecules Targeting the Flavivirus E Protein with Broad-Spectrum Activity and Antiviral Efficacy in Vivo
20. Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein
21. The pUL37 tegument protein guides alpha-herpesvirus retrograde axonal transport to promote neuroinvasion
22. GNF-2 Inhibits Dengue Virus by Targeting Abl Kinases and the Viral E Protein
23. Crystal Structure of the Herpesvirus Inner Tegument Protein UL37 Supports Its Essential Role in Control of Viral Trafficking
24. REMDESIVIR RETAINS POTENT ACTIVITY AGAINST SARS-CoV-2 VARIANTS OF CONCERN.
25. Sialyltransferase Regulates Nervous System Function in Drosophila.
26. Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine C-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV
27. Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice.
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