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6. Objectively Measured Physical Activity in Patients with COPD: Recommendations from an International Task Force on Physical Activity.

Author

Demeyer, Heleen, Mohan, Divya, Burtin, Chris, Vaes, Anouk W, Heasley, Matthew, Bowler, Russell P, Casaburi, Richard, Cooper, Christopher B, Corriol-Rohou, Solange, Frei, Anja, Hamilton, Alan, Hopkinson, Nicholas S, Karlsson, Niklas, Man, William D-C, Moy, Marilyn L, Pitta, Fabio, Polkey, Michael I, Puhan, Milo, Rennard, Stephen I, Rochester, Carolyn L, Rossiter, Harry B, Sciurba, Frank, Singh, Sally, Tal-Singer, Ruth, Vogiatzis, Ioannis, Watz, Henrik, Lummel, Rob Van, Wyatt, Jeremy, Merrill, Debora D, Spruit, Martijn A, Garcia-Aymerich, Judith, and Troosters, Thierry

Subjects
Biomedical and Clinical Sciences, Public Health, Health Sciences, Clinical Sciences, Clinical Research, Chronic Obstructive Pulmonary Disease, Lung, Physical Activity, Prevention, Respiratory, Stroke, Cardiovascular, Cancer, Oral and gastrointestinal, physical activity, accelerometery, standardization, methodology, Chronic Lung Disease Biomarker and Clinical Outcome Assessment Qualification Consortium Task Force on Physical Activity, Physical activity
Abstract

Physical activity (PA) is of key importance for health among healthy persons and individuals with chronic obstructive pulmonary disease (COPD). PA has multiple dimensions that can be assessed and quantified objectively using activity monitors. Moreover, as shown in the published literature, variable methodologies have been used to date to quantify PA among individuals with COPD, precluding clear comparisons of outcomes across studies. The present paper aims to provide a summary of the available literature for the rationale behind using objectively measured PA and proposes a standardized methodology for assessment, including standard operating procedures for future research. The present paper, therefore, describes the concept of PA, reports on the importance of PA, summarizes the dimensions of PA, provides a standard operating procedure on how to monitor PA using objective assessments, and describes the psychometric properties of objectively measured PA. The present international task force recommends implementation of the standard operating procedure for PA data collection and reporting in the future. This should further clarify the relationship between PA and clinical outcomes, test the impact of treatment interventions on PA in individuals with COPD, and successfully propose a PA endpoint for regulatory qualification in the future.

Published
2021

11. Londrina Activities of Daily Living Protocol: validity, reliability, minimal detectable change, and standard error of measurement in adults with asthma.

Author

Puzzi, Vitória Cavalheiro, Oliveira, Joice Mara de, Alves, Thainá Bessa, Silva, Jessica Priscila da Conceição, Pitta, Fabio, and Furlanetto, Karina Couto

Subjects
CHRONIC cough, INTRACLASS correlation, MEASUREMENT errors, CHEST pain, ACTIVITIES of daily living
Abstract

Introduction: Asthma symptoms are dyspnea, chronic cough, wheezing, chest tightness, or chest discomfort, which can directly limit the activities of daily living (ADL), which is frequently reported by adults with asthma. Evaluating ADL with a reliable protocol at the usual speed is necessary. Objectives: To investigate the validity, reliability, minimal detectable change (MDC), and standard error of measurement (SEM) of the Londrina ADL Protocol (LAP) for adults with asthma. Methods: Adults with asthma were evaluated with the LAP test. Spearman's correlation coefficient was used to verify validity with the 6-min walk test (6MWT), Glittre-ADL test, and London Chest Activity of Daily Living (LCADL). To test the reliability, the test was reapplied in at least 30 min; the Wilcoxon test and Intraclass Correlation Coefficient (ICC), SEM, MDC, and learning effect were performed. Results: Fifty-three individuals were included (26% men, 43 ± 15 years, BMI 28 ± 8 kg/m2, FEV1 70 ± 24%predicted). For convergent validity, the LAP test was correlated with the 6MWT, Glittre-ADL, and LCADL scale (r = −0.49, 0.71, and 0.30, respectively; p < 0.03). There was a difference in test-retest (p < 0.0001) and reliability analysis shows ICC3 of 0.94, SEM of 14.88 s (22%), and MDC of 41.23 s (15%). Furthermore, the individuals performed the second test with −23 ± 19 (7.9%) s. Conclusion: The LAP test is valid and reliable for assessing limitations during ADL in adults with asthma. Considerable learning effect was observed, therefore, the best of two measures may avoid underestimation. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Functional Measures in Non-COPD Chronic Respiratory Diseases: A Systematic Review.

Author

Zamboti, Camile Ludovico, Pimpão, Heloise Angélico, Bertin, Larissa Dragonetti, Krinski, Gabriela Garcia, Garcia, Tathielle, dos Santos Filho, Sandro Laerth Souza, Cavalheri, Vinicius, Pitta, Fabio, and Camillo, Carlos Augusto

Subjects
INTERSTITIAL lung diseases, CHRONIC obstructive pulmonary disease, PULMONARY arterial hypertension, CYSTIC fibrosis, AEROBIC capacity
Abstract

Background/Objectives: The extensive range of instruments designed for evaluating functional performance (FP) in chronic respiratory diseases (CRD) other than chronic obstructive pulmonary disease (COPD) presents a challenge in selecting the most appropriate one. Therefore, this systematic review aimed to summarise FP instruments, their measurement properties, their minimum clinically important differences, and their associations with CRD course-related events or prognosis in non-COPD CRD. Methods: Studies employing patient-reported or performance-based instruments to assess FP in non-COPD CRD were systematically identified in the PubMed, PEDro, Embase, and Cochrane Library databases. COPD-exclusive studies or those solely reporting exercise capacity tests were excluded. Examination focused on measurement properties and associations with CRD course-related events or prognosis. The risk of bias was evaluated using the COSMIN, Downs and Black, and PEDro checklists based on the study design. Results: A total of 216 studies across seven CRD categories [asthma, bronchiectasis, cystic fibrosis, interstitial lung disease (ILD), pulmonary arterial hypertension (PAH), pre-/post-lung-transplantation] from various study types were included. Thirty-three instruments were identified, with the SF-36 questionnaire's physical function domain being the most commonly used patient-reported tool. The 1 min sit-to-stand test was the most extensively studied performance-based measure, with its measurement properties frequently reported in non-COPD CRD studies. Associations with events were infrequently documented, primarily in ILD and PAH studies related to mortality. Conclusions: Despite the prevalent use of FP instruments, limited information exists concerning their measurement properties and clinical implications. This review furnishes a concise summary of available evidence, aiding informed clinical decisions when selecting FP tools for non-COPD CRD. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Translation, cross-cultural adaptation, and measurement properties of the Brazilian-Portuguese version of the idiopathic pulmonary fibrosis-specific version of the Saint George's Respiratory Questionnaire (SGRQ-I) for patients with interstitial lung disease

Author

Aguiar, Wagner Florentin, Mantoani, Leandro Cruz, Silva, Humberto, Zamboti, Camile Ludovico, Garcia, Thatielle, Cavalheri, Vinicius, Ribeiro, Marcos, Yorke, Janelle, Pitta, Fabio, and Camillo, Carlos Augusto

Published
2021
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19. Cardiology referral during the COVID-19 pandemic

Author

Santorio, Nathalia Conci, Cardozo, Francisco Akira Malta, Miada, Rodrigo Freddi, Pitta, Fabio Grunspun, Tavares, Caio de Assis Moura, Habrum, Fabio Cetinic, Pinesi, Henrique Trombini, Magalhães, Iuri Resedá, Menezes, Maria Clara Saad, Caramelli, Bruno, and Calderaro, Daniela

Published
2021
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25. Patient-Centered Outcomes

Author

Furlanetto, Karina C., Hernandes, Nidia A., Pitta, Fabio, Clini, Enrico, editor, Holland, Anne E., editor, Pitta, Fabio, editor, and Troosters, Thierry, editor

Published
2018
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28. Physical inactivity and sedentary behavior in individuals with stable COPD non-infected by SARS-CoV-2 during the COVID-19 pandemic

Author

Fontana, Andréa Daiane, Santana, André Vinicius, Almeida, Rafaela Cristina, Mantoani, Leandro Cruz, Camillo, Carlos Augusto, Furlanetto, Karina Couto, Hernandes, Nidia Aparecida, Pitta, Fabio, Fontana, Andréa Daiane, Santana, André Vinicius, Almeida, Rafaela Cristina, Mantoani, Leandro Cruz, Camillo, Carlos Augusto, Furlanetto, Karina Couto, Hernandes, Nidia Aparecida, and Pitta, Fabio

Abstract

Objective: to identify factors associated to sedentary behavior and physical inactivity in individuals with stable chronic obstructive pulmonary disease (COPD) non-infected by SARS-CoV-2 during the COVID-19 pandemic, and to identify possible favorable conditions during social isolation in individuals who performed pulmonary rehabilitation in the pre-pandemic period. Method: time/day in sedentary activities and moderate/vigorous physical activities (SA and MVPA, respectively), history of previous rehabilitation, laboural activity, symptoms, insecurity and quality of life (Medical Outcomes Study 36-item Short-Form Health Survey [SF-36]) were assessed during strict social isolation due to the COVID-19 pandemic. Individuals were classified as sedentary if presenting time/day in SA >8.5 h/day and physically inactive if presenting time/day in MVPA <150 min/week. Result: The sample consisted of 33 individuals (69±7 years; 20 male). Regarding the SF-36, non-sedentary individuals presented better functional capacity than sedentary individuals (65 [38-73] vs. 33 [20-63] points; p=0.01) whereas physically active individuals presented better physical and social function than physically inactive individuals (100 [100-100] vs. 50 [25-100] points, p=0.049; and 100 [100-100] vs. 75 [69-100] points, p=0.022, respectively). Having a professional activity and working outside were associated with non-sedentary behavior (X2=5.93; p=0.025 and X2=7.03; p=0.009, respectively). Having undergone rehabilitation previously to the pandemic was associated with less insecurity to walk outside (X2=4.95; p=0.034) and better perception of symptoms’ worsening (X2=5.46; p=0.033). Conclusion: non-sedentarism was associated with functional capacity and laboural activity; active lifestyle was associated with physical and social function; and previous rehabilitation was associated with better symptoms’ recognition and less insecurity.

Published
2024

29. Are the Effects of High-Intensity Exercise Training Different in Patients with COPD Versus COPD+Asthma Overlap?

Author

Rodrigues, Antenor, de Oliveira, Joice Mara, Furlanetto, Karina Couto, Machado, Felipe Vilaça Cavallari, Belo, Letícia Fernandes, Schneider, Lorena Paltanin, Morita, Andrea Akemi, Andrelo, Ana Carolina, Fonseca, Jéssica, Brito, Igor Lopes, Paes, Thaís, Felcar, Josiane Marques, Probst, Vanessa Suziane, Hernandes, Nidia Aparecida, and Pitta, Fabio

Published
2020
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31. Construct validity of the Post-COVID-19 Functional Status Scale in adult subjects with COVID-19

Author

Machado, Felipe V. C., Meys, Roy, Delbressine, Jeannet M., Vaes, Anouk W., Goërtz, Yvonne M. J., van Herck, Maarten, Houben-Wilke, Sarah, Boon, Gudula J. A. M., Barco, Stefano, Burtin, Chris, van ’t Hul, Alex, Posthuma, Rein, Franssen, Frits M. E., Spies, Yvonne, Vijlbrief, Herman, Pitta, Fabio, Rezek, Spencer A., Janssen, Daisy J. A., Siegerink, Bob, Klok, Frederikus A., and Spruit, Martijn A.

Published
2021
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40. Effects of an online behaviour change intervention to promote physical activity in adults with asthma: preliminary data of a randomized controlled trial

Author

Oliveira, Joice Mara, primary, Pedroso, Ariele, additional, Correia, Natielly Soares, additional, Melo, Denner Ildemar Feitosa, additional, Bidoia, Caroline Sydloski, additional, Pitta, Fabio, additional, Karloh, Manuela, additional, Matias, Thiago Sousa, additional, Lima, Fabiano Francisco, additional, Da Cunha, Marieta Cabral Amaral, additional, Carvalho, Celso R F, additional, and Furlanetto, Karina Couto, additional

Published
2023
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45. The impact of sleep duration on physical activity in daily life in patients with idiopathic pulmonary fibrosis.

Author

Silva, Humberto, Mantoani, Leandro C., Aguiar, Wagner F., Gonçalves, Aline F. L., da Silva, Thatielle G., Zamboti, Camile L., Ribeiro, Marcos, Probst, Vanessa S., Pitta, Fabio, and Camillo, Carlos A.

Subjects
CROSS-sectional method, PEARSON correlation (Statistics), RESEARCH funding, SPIROMETRY, T-test (Statistics), DATA analysis, MULTIPLE regression analysis, DESCRIPTIVE statistics, MANN Whitney U Test, ACTIGRAPHY, SLEEP duration, STATISTICS, IDIOPATHIC pulmonary fibrosis, SLEEP quality, DATA analysis software, PHYSICAL activity, ACTIVITIES of daily living, DISEASE complications
Abstract

Despite the high prevalence of sleep disturbances in idiopathic pulmonary fibrosis (IPF), the relationship between physical activity in daily life (PADL) and sleep in this population remains unclear Investigate the impact of sleep on different domains of PADL in IPF and characterize their PADL profile Sixty-seven participants (thirty-three with IPF and thirty-four healthy subjects [control group]) were included. The subjects underwent assessments of pulmonary function, exercise capacity, respiratory and peripheral muscle strength, PADL, sleep, dyspnea, and health-related quality of life. PADL and sleep measures were assessed using an activity monitor (Actigraph®, wGT3x-BT). Associations between sleep and PADL were done using correlation and regression models. In the IPF, sleep duration at night associated significantly with step counts, sedentary, light, and moderate-to-vigorous physical activity (MVPA) (−0.82 ≤ R ≤ 0.43; p <.05 for all). Lung function and sleep partially explained PADL variables (0.19 ≤ R2 ≤ 0.65, p <.05 for all). Compared to controls, the IPF subjects presented lower step counts, less time spent in MVPA, standing position, and more time spent in lying position (p <.05, for all) Sleep duration is associated with PADL in IPF. The PADL profile of patients is worse than in control subjects. [ABSTRACT FROM AUTHOR]

Published
2024
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