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Scientific data governance should prioritize maximizing the utility of data throughout the research lifecycle. Research software systems that enable analysis reproducibility inform data governance policies and assist administrators in setting clear guidelines for data reuse, data retention, and the management of scientific computing needs. Proactive analysis reproducibility and data governance are integral and interconnected components of research lifecycle management.

The high incidence of irreproducible research has led to urgent appeals for transparency and equitable practices in open science. For the scientific disciplines that rely on computationally intensive analyses of large data sets, a granular understanding of the analysis methodology is an essential component of reproducibility. This paper discusses the guiding principles of a computational reproducibility framework that enables a scientist to proactively generate a complete reproducible trace as analysis unfolds, and share data, methods and executable tools as part of a scientific publication, allowing other researchers to verify results and easily re-execute the steps of the scientific investigation.