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37 results on '"Pisaturo, Valerio"'

1. Clinical and laboratory key performance indicators in IVF: A consensus between the Italian Society of Fertility and Sterility and Reproductive Medicine (SIFES-MR) and the Italian Society of Embryology, Reproduction and Research (SIERR)

Author

Vaiarelli, Alberto, Zacà, Carlotta, Spadoni, Valentina, Cimadomo, Danilo, Conforti, Alessandro, Alviggi, Carlo, Palermo, Roberto, Bulletti, Carlo, De Santis, Lucia, Pisaturo, Valerio, Vigiliano, Vincenzo, Scaravelli, Giulia, Ubaldi, Filippo Maria, and Borini, Andrea

Published
2023
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2. Sustainability in the IVF laboratory: recommendations of an expert panel

Author

Farlie, Francesca, Palmer, Giles A., Cohen, Jacques, Calcagni, Charles, Gorbunova, Anna, Lawford Davies, James, Loscher, Carol, O'Raghallaigh, Roisin, Sharp, Timothy, Smale, Daniela, Sörme, Pernilla, Thiel, Cassandra L., Alteri, Alessandra, Campbell, Alison, Crompton, Kirsty, Mortimer, Sharon, Pisaturo, Valerio, Tolpe, Annelies, and Alikani, Mina

Published
2024
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5. Conventional in vitro fertilisation rather than intracytoplasmic sperm injection when only one oocyte is retrieved: Time to overcome irrational fears.

Author

Pisaturo, Valerio, Reschini, Marco, Guarneri, Cristina, Sanzani, Elena, Paffoni, Alessio, and Somigliana, Edgardo

Subjects
*RESEARCH funding, *FISHER exact test, *TREATMENT effectiveness, *RETROSPECTIVE studies, *PREGNANCY outcomes, *DESCRIPTIVE statistics, *MULTIVARIATE analysis, *MANN Whitney U Test, *CHI-squared test, *FERTILIZATION in vitro, *STATISTICS, *CONFIDENCE intervals, *DATA analysis software, *OOCYTE retrieval
Abstract

Background: The use of intracytoplasmic sperm injection (ICSI) currently extends beyond male factor infertility, notably replacing conventional in vitro fertilisation (IVF) in scenarios like limited oocyte availability, where it is used as a precaution against complete fertilisation failure. While existing studies on the use of conventional IVF in such situations provide some reassurance, the available evidence is somewhat insufficient and ICSI is commonly used. Aims: To evaluate whether conventional IVF can be a feasible option when only one oocyte is retrieved. Materials and Methods: A retrospective study was performed to evaluate the fertilisation rate with conventional IVF in women retrieving only one oocyte and whose partner had normal semen. The study aimed at evaluating whether the fertilisation rate was aligned with the threshold indicated by recognized IVF laboratory performance indicators (Vienna Consensus). Clinical pregnancy and live birth rates were secondary outcomes. Results: Out of 304 cycles with a single oocyte inseminated with conventional IVF, 209 achieved normal fertilisation and 82 did not. Thirteen had no mature oocytes. The fertilisation rate was 69% (95% CI: 63–74%) and increased to 72% (95% CI: 66–77%) when immature oocytes were excluded. The fertilisation rate surpassed the minimum competency threshold of the Vienna Consensus (60%), even if below the benchmark value (75%). Clinical pregnancy and live birth rates per oocyte retrieval were 10% and 8%, respectively. Univariate and multivariate analyses failed to identify any predictive factor of fertilisation. Conclusion: Conventional IVF with one oocyte met Vienna Consensus standards even if it fell short of higher benchmarks. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Sustainability in the IVF laboratory: recommendations of an expert panel

Author

Farlie, Francesca, primary, Palmer, Giles Anthony, additional, Cohen, Jacques, additional, Calcagni, Charles, additional, Gorbunova, Anna, additional, Davies, James Lawford, additional, Loscher, Carol, additional, Sharp, Timothy, additional, Smale, Daniela, additional, Sörme, Pernilla, additional, Thiel, Cassandra L, additional, Alteri, Alessandra, additional, Campbell, Alison, additional, Crompton, Kirsty, additional, O'Raghallaigh, Roisin, additional, Mortimer, Sharon, additional, Pisaturo, Valerio, additional, Tolpe, Annelies, additional, and Alikani, Mina, additional

Published
2023
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16. Fertility Preservation as an Option for Women with Genetic Disorders: Insights from a SWOT Analysis on Elective Oocyte Freezing and Preimplantation Genetic Testing

Author

Cermisoni, Greta Chiara, primary, Pisaturo, Valerio, additional, Vanni, Valeria Stella, additional, Minetto, Sabrina, additional, Pagliardini, Luca, additional, Masciangelo, Rossella, additional, Candiani, Massimo, additional, Papaleo, Enrico, additional, and Alteri, Alessandra, additional

Published
2023
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17. Surveillance of clinical research integrity in medically assisted reproduction: a systematic review of retracted publications

Author

Minetto, Sabrina, Zanirato, Mara, Makieva, Sofia; https://orcid.org/0000-0001-6143-3553, Marzanati, Daria, Esposito, Stefania, Pisaturo, Valerio, Costa, Mauro, Candiani, Massimo, Papaleo, Enrico, Alteri, Alessandra, Minetto, Sabrina, Zanirato, Mara, Makieva, Sofia; https://orcid.org/0000-0001-6143-3553, Marzanati, Daria, Esposito, Stefania, Pisaturo, Valerio, Costa, Mauro, Candiani, Massimo, Papaleo, Enrico, and Alteri, Alessandra

Abstract

Background and purpose Retraction is a significant consequence of scientific research, resulting from various factors ranging from unintentional errors to intentional misconduct. Previous reviews on retracted publications in obstetrics and gynecology have identified “article duplication,” “plagiarism,” and “fabricated results” as the main reasons for retraction. However, the extent of retracted articles in the literature on medically assisted reproduction (MAR) remains unclear. This systematic review aimed to assess the number and characteristics of retracted articles in the field of MAR. Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed for this study. A comprehensive literature search was conducted on the PubMed database from 1993 to February 2023, limited to English articles and including all 283 terms from the International Glossary on Infertility and Fertility Care. To identify retracted studies, a specific query combining the 283 terms from the glossary with a retraction-related keyword was used. Only studies focused on MAR and involving human subjects were included. Results The electronic search yielded a total of 523,067 records in the field of infertility and fertility care. Among these, a total of 2,458 records were identified as retracted. The citation retraction rate was found to be 0.47% (2,458/523,067; 95%CI 0.45–0.49), and the citation retraction rate for randomized controlled trials (RCTs) was 0.20% (93/45,616; 95%CI 0.16–0.25). A total of 39 retracted articles specifically related to MAR were identified. Among these, 41.0% were RCTs (n = 16), 15.4% were reviews (n = 6), and 10.3% were retrospective studies (n = 4) or prospective studies (n = 4). Most of the retractions occurred shortly after publication, with “plagiarism” being the most common reason for retraction, followed by “duplicate publication.” Discussion The issue of retraction exists within the field of infertility and fertilit

Published
2023

18. Post-Thaw Day 5 Blastocyst Culture Time Prior to Transfer Does Not Affect Assisted Reproduction Technology (ART) Outcomes in Frozen-Thawed Embryo Transfer Cycles

Author

Ciaffaglione, Marta, primary, Reschini, Marco, additional, Balli, Martina, additional, Guarneri, Cristina, additional, Palermo, Maria Carla, additional, Pinna, Monica, additional, Pisaturo, Valerio, additional, Somigliana, Edgardo, additional, Paffoni, Alessio, additional, and Vigano’, Paola, additional

Published
2022
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21. Opportunities and Limits of Conventional IVF versus ICSI: It Is Time to Come off the Fence

Author

Balli, Martina; https://orcid.org/0000-0003-0791-2021, Cecchele, Anna, Pisaturo, Valerio; https://orcid.org/0000-0003-4247-1970, Makieva, Sofia, Carullo, Giorgia, Somigliana, Edgardo, Paffoni, Alessio, Viganò, Paola; https://orcid.org/0000-0003-3674-5912, Balli, Martina; https://orcid.org/0000-0003-0791-2021, Cecchele, Anna, Pisaturo, Valerio; https://orcid.org/0000-0003-4247-1970, Makieva, Sofia, Carullo, Giorgia, Somigliana, Edgardo, Paffoni, Alessio, and Viganò, Paola; https://orcid.org/0000-0003-3674-5912

Abstract

Conventional IVF (c-IVF) is one of the most practiced assisted reproductive technology (ART) approaches used worldwide. However, in the last years, the number of c-IVF procedures has dropped dramatically in favor of intracytoplasmic sperm injection (ICSI) in cases of non-male-related infertility. In this review, we have outlined advantages and disadvantages associated with c-IVF, highlighting the essential steps governing its success, its limitations, the methodology differences among laboratories and the technical progress. In addition, we have debated recent insights into fundamental questions, including indications regarding maternal age, decreased ovarian reserve, endometriosis, autoimmunity, single oocyte retrieval-cases as well as preimplantation genetic testing cycles. The “overuse” of ICSI procedures in several clinical situations of ART has been critically discussed. These insights will provide a framework for a better understanding of opportunities associated with human c-IVF and for best practice guidelines applicability in the reproductive medicine field.

Published
2022

24. Phthalates and Bisphenol A: Presence in Blood Serum and Follicular Fluid of Italian Women Undergoing Assisted Reproduction Techniques

Author

Paoli, Donatella, primary, Pallotti, Francesco, additional, Dima, Anna Pia, additional, Albani, Elena, additional, Alviggi, Carlo, additional, Causio, Franco, additional, Dioguardi, Carola Conca, additional, Conforti, Alessandro, additional, Ciriminna, Rosanna, additional, Fabozzi, Gemma, additional, Giuffrida, Giuseppe, additional, Gualtieri, Roberto, additional, Minasi, Maria Giulia, additional, Ochetti, Simona, additional, Pisaturo, Valerio, additional, Racca, Cinzia, additional, Rienzi, Laura, additional, Sarcina, Elena, additional, Scarica, Catello, additional, Tomasi, Giovanna, additional, Verlengia, Cristina, additional, Villeggia, Rita, additional, Zullo, Federica, additional, Lenzi, Andrea, additional, Botrè, Francesco, additional, and De Santis, Lucia, additional

Published
2020
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30. Cryopreserved Gamete and Embryo Transport: Proposed Protocol and Form Templates—SIERR (Italian Society of Embryology, Reproduction, and Research).

Author

Paoli, Donatella, Dal Canto, Mariabeatrice, Baldi, Elisabetta, Cervi, Marta, Ciotti, Patrizia Maria, Ciriminna, Rosanna, Dabizzi, Sara, Farace, Dario, Garello, Cristina, Garolla, Andrea, Giacchetta, Daniela, Gualtieri, Roberto, Menegazzo, Massimo, Minasi, Maria Giulia, Oneta, Monica, Pisaturo, Valerio, Rienzi, Laura, Scarica, Catello, Taliani, Gloria, and De Santis, Lucia

Published
2021
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31. Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors

Author

Bajetto, Adriana, primary, Pattarozzi, Alessandra, additional, Corsaro, Alessandro, additional, Barbieri, Federica, additional, Daga, Antonio, additional, Bosio, Alessia, additional, Gatti, Monica, additional, Pisaturo, Valerio, additional, Sirito, Rodolfo, additional, and Florio, Tullio, additional

Published
2017
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36. Monozygotic twin rate among ART centers: a multicenter analysis of data from 18 Italian units

Author

Giulia Scaravelli, Valerio Pisaturo, Paolo Emanuele Levi Setti, Filippo Maria Ubaldi, Claudia Livi, Andrea Borini, Ermanno Greco, Maria Teresa Villani, Maria Elisabetta Coccia, Alberto Revelli, Giuseppe Ricci, Francesco Fusi, Mauro Costa, Emanuela Migliorati, Roberto De Luca, Vincenzo Vigiliano, Simone Bolli, Marco Reschini, Scaravelli, Giulia, Pisaturo, Valerio, Levi Setti, Paolo Emanuele, Ubaldi, Filippo Maria, Livi, Claudia, Borini, Andrea, Greco, Ermanno, Villani, Maria Teresa, Coccia, Maria Elisabetta, Revelli, Alberto, Ricci, Giuseppe, Fusi, Francesco, Costa, Mauro, Migliorati, Emanuela, De Luca, Roberto, Vigiliano, Vincenzo, Bolli, Simone, and Reschini, Marco

Subjects
Reproductive Techniques, Assisted, Twinning, Monozygotic, Multiple pregnancy, Obstetrics and Gynecology, Twin, General Medicine, Twins, Monozygotic, Embryo Transfer, Monozygotic, Reproductive Medicine, Pregnancy, IVF, Genetics, Pregnancy, Twin, Humans, Female, Genetics (clinical), ART, Developmental Biology, Retrospective Studies
Abstract

Purpose The risk of monozygotic twins (MZTs) is increased in couples undergoing assisted reproductive technology (ART) treatments. Several systematic reviews have investigated the possible determinants linked to ART, but results obtained have not been conclusive. The study aims to investigate whether the incidence of MZT differed among ART centers. Methods This is a multicenter retrospective cohort study using the Italian ART National Registry database and involving the centers reporting data from individual ART cycles from 2015 to 2019. To investigate the incidence of MZT, only single embryo transfer cycles were considered. Women who had sex-discordant deliveries were excluded. MZT rate was calculated as the number of multiple pregnancies (more than one gestational sac at first ultrasound) out of the total number of clinical pregnancies. A binomial distribution model was used to determine the 95% CI of the frequency of MZT. Results Eighteen centers were included, and they provided data on 10,433 pregnancies. The total number of MZT was 162, corresponding to an incidence of 1.5% (95% CI: 1.3-1.8%). The rate of MZT among centers varied between 0% (95% CI: 0.0-25.9%) and 3.2% (95% CI: 1.3-8.1%). All the 95% CIs included 1.5%, rejecting the hypothesis that the MZT rate may significantly differ among centers. Conclusions The rate of MZT did not significantly vary among ART centers. Local factors are unlikely to explain the increased rate of MZT in ART pregnancies.

Published
2022

37. Cryopreserved Gamete and Embryo Transport: Proposed Protocol and Form Templates-SIERR (Italian Society of Embryology, Reproduction, and Research)

Author

Gloria Taliani, Laura Rienzi, Maria Giulia Minasi, Dario Farace, Daniela Giacchetta, Valerio Pisaturo, Andrea Garolla, Elisabetta Baldi, Massimo Menegazzo, Catello Scarica, Rosanna Ciriminna, Donatella Paoli, S. Dabizzi, Patrizia Maria Ciotti, Cristina Garello, Roberto Gualtieri, Monica Oneta, Marta Cervi, Mariabeatrice Dal Canto, Lucia De Santis, Paoli, Donatella, Dal Canto, Mariabeatrice, Baldi, Elisabetta, Cervi, Marta, Ciotti, Patrizia Maria, Ciriminna, Rosanna, Dabizzi, Sara, Farace, Dario, Garello, Cristina, Garolla, Andrea, Giacchetta, Daniela, Gualtieri, Roberto, Menegazzo, Massimo, Minasi, Maria Giulia, Oneta, Monica, Pisaturo, Valerio, Rienzi, Laura, Scarica, Catello, Taliani, Gloria, and De Santis, Lucia

Subjects
Decree, Male, Process management, Traceability, Reproductive Techniques, Assisted, media_common.quotation_subject, Acknowledgement, Medicine (miscellaneous), ART, gamete and embryo transport, oocyte cryopreservation, receiving center, sending center, sperm cryopreservation, Reproductive technology, General Biochemistry, Genetics and Molecular Biology, Humans, Quality (business), media_common, Protocol (science), Cryopreservation, Reproduction, Cell Biology, General Medicine, Focus group, Germ Cells, Italy, Gamete transport, Business
Abstract

Introduction: In Italy, the transport of cryopreserved biological material is controlled by several Decrees (Legislative Decree No. 191/2007 and No. 16/2010 and Health Ministry's Decree of October 10, 2012). Given the nature of their applications, the transport of reproductive cells has peculiar quality and safety requirements that must be applied universally, minimizing the chance of error. To standardize the cross-border shipping procedure to meet the quality, traceability, and safety criteria for cells and tissues, it is appropriate to establish a unified process using the same tools, forms, and communication channels. Methods: A working group has been created by SIERR. This "FOCUS Group" was constituted by representatives from Italian-assisted reproductive technology centers and sperm banks who worked together to define joint procedural steps and create specific forms to support the movement of cryopreserved samples. Results: The FOCUS Group identified the critical steps in the communication procedures between Italian centers and created the related forms: patient authorization, request from the recipient center, critical checks carried out by both sending and recipient centers, start of samples transfer, collection, transport and taking responsibility of the biological material, acknowledgment of samples arrival, and acknowledgement of any adverse event that occurred. Discussion: Indications on shipping between tissue institutions and legal responsibilities are important points and a working protocol with shared transport forms has been defined. Standard Operating Procedures are necessary in light of the increasingly widespread movement of biological samples between the various countries, and represent a valid means of support for the patients who could have a higher awareness of safety and traceability during each stage of gamete transport.

Published
2020

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