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14 results on '"Pisaturo, L"'

10. Treatment of hypopituitarism in infancy. Effect on head circumference growth

Author

Di Maio, S., Salerno, M., Gasparini, N., Fusco, T., Pisaturo, L., Giuliana Valerio, Di Maio, S, Salerno, Mariacarolina, Gasparini, N, Fusco, T, Pisaturo, L, and Valerio, G.

Subjects
Male, Thyroxine, Adolescent, Anthropometry, Human Growth Hormone, Humans, Infant, Drug Therapy, Combination, Female, Child, Head, Hypopituitarism, Retrospective Studies
Abstract

Head circumference of children with multiple pituitary-hormone deficiency (MPHD) may be subnormal for age. Moreover it is known that linear growth in infancy is growth-hormone (GH) dependent. Therefore, aim of the study has been to compare head circumference measurements in children with hypopituitarism after L-thyroxine (L-T4) therapy alone, before therapy with GH, and after GH was added to the therapy. Five infants (2 girls, 3 boys) with MPHD, diagnosed and treated before the age of 2 years and whose auxological parameters records during L-T4 therapy alone were available, were retrospectively studied. Head circumference and length measurements were expressed as standard deviation score (SDS). Weight measurements were expressed as weight for length ratio percentage. Initially treated with L-T4 alone for a mean period of 4, 5 months, there were neither positive effects on head circumference nor on linear growth. A significant catch-up growth was observed only employing GH therapy in addition to L-T4: mean head circumference SDS and length SDS increased respectively from -2.20 to -0.89 SDS and from -4.16 to -0.87 SDS after a mean period of 18 months of combined GH and L-T4 therapy. Therefore, head circumference growth, in infancy, is growth hormone dependent as well as linear growth, and during GH treatment, monitoring head circumference growth is important as much as monitoring linear growth.

11. Fetal goiter in a iodine-deficient area

Author

Angela Mariano, L. Pisaturo, Vincenzo Macchia, Mariacarolina Salerno, S. Di Maio, Salerno, Mariacarolina, DI MAIO, S, Pisaturo, L, Mariano, A, Macchia, Vincenzo, Di Maio, S., Pisaturo, L., Mariano, A., and Macchia, V.

Subjects
Fetus, Goiter, business.industry, Endocrinology, Diabetes and Metabolism, Fetal goiter, iodine-deficient area, Physiology, chemistry.chemical_element, medicine.disease, Iodine, Iodine deficiency, Endocrinology, chemistry, medicine, business
Published
1998

12. Precocious puberty in Sanfilippo IIIA disease: diagnosis and follow-up of two new cases

Author

A. Piccirillo, P. Di Natale, Pietro Strisciuglio, G. Muzzi, L. Pisaturo, Daniela Concolino, Concolino, D, Muzzi, G, Pisaturo, L, Piccirillo, A, Di Natale, P, and Strisciuglio, Pietro

Subjects
Agonist, Male, medicine.medical_specialty, Pediatrics, Adolescent, medicine.drug_class, Mucopolysaccharidosis, Central precocious puberty, DNA Mutational Analysis, Puberty, Precocious, Disease, Child Behavior Disorders, Gonadotropin-Releasing Hormone, Mucopolysaccharidosis III, Internal medicine, Genetics, Medicine, Precocious puberty, Humans, Child, Mucopolysaccharidosis Type IIIA, Genetics (clinical), Triptorelin Pamoate, business.industry, Final height, Follow up studies, Brain, General Medicine, medicine.disease, Magnetic Resonance Imaging, Body Height, Luteolytic Agents, Endocrinology, Mutation, business
Abstract

To date the association between mucopolysaccharidosis (MPS) IIIA and precocious puberty has been found in only three polish patients. We observed two children affected by MPS IIIA with central precocious puberty (CPP) both treated with GnRH agonists. The occurrence of CPP in both patients with MPS IIIA suggests that it is necessary to look for an association between the two conditions. The follow-up of our two patients leads us to believe also that GnRH agonist treatment can have a beneficial effect on final height and probably on the improvement of behavioural problems.

Published
2007

13. Hearing impairment in congenital hypothyroidism

Author

SALERNO, MARIACAROLINA, S. Di Maio, A. Officioso, N. Gasparini, P. Giannini, T. Lettiero, L. Pisaturo, E. Marciano, Salerno, Mariacarolina, Di Maio, S., Officioso, A., Gasparini, N., Giannini, P., Lettiero, T., Pisaturo, L., and Marciano, E.

Published
1999

14. Treatment of hypopituitarism in infancy. Effect on head circumference growth.

Author

Di Maio S, Salerno M, Gasparini N, Fusco T, Pisaturo L, and Valerio G

Subjects
Drug Therapy, Combination, Female, Humans, Infant, Male, Retrospective Studies, Head growth & development, Human Growth Hormone therapeutic use, Hypopituitarism drug therapy, Thyroxine therapeutic use
Abstract

Background: Head circumference of children with multiple pituitary-hormone deficiency (MPHD) may be subnormal for age. Moreover it is known that linear growth in infancy is growth-hormone (GH) dependent. Therefore, aim of the study has been to compare head circumference measurements in children with hypopituitarism after L-thyroxine (L-T4) therapy alone, before therapy with GH, and after GH was added to the therapy., Methods: Five infants (2 girls, 3 boys) with MPHD, diagnosed and treated before the age of 2 years and whose auxological parameters records during L-T4 therapy alone were available, were retrospectively studied. Head circumference and length measurements were expressed as standard deviation score (SDS). Weight measurements were expressed as weight for length ratio percentage., Results: Initially treated with L-T4 alone for a mean period of 4, 5 months, there were neither positive effects on head circumference nor on linear growth. A significant catch-up growth was observed only employing GH therapy in addition to L-T4: mean head circumference SDS and length SDS increased respectively from -2.20 to -0.89 SDS and from -4.16 to -0.87 SDS after a mean period of 18 months of combined GH and L-T4 therapy., Conclusions: Therefore, head circumference growth, in infancy, is growth hormone dependent as well as linear growth, and during GH treatment, monitoring head circumference growth is important as much as monitoring linear growth.

Published
1999

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