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306 results on '"Pisano, David G."'

1. RUbioSeq+: An Application that Executes Parallelized Pipelines to Analyse Next-Generation Sequencing Data

Author

Rubio-Camarillo, Miriam, López-Fernández, Hugo, Gómez-López, Gonzalo, Carro, Ángel, Fernández, José María, Fdez-Riverola, Florentino, Glez-Peña, Daniel, Pisano, David G., Kacprzyk, Janusz, Series editor, Saberi Mohamad, Mohd, editor, Rocha, Miguel P., editor, Fdez-Riverola, Florentino, editor, Domínguez Mayo, Francisco J., editor, and De Paz, Juan F., editor

Published
2016
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3. Data from Long-Range Epigenetic Silencing Associates with Deregulation of Ikaros Targets in Colorectal Cancer Cells

Author

Javierre, Biola M., primary, Rodriguez-Ubreva, Javier, primary, Al-Shahrour, Fatima, primary, Corominas, Marina, primary, Graña, Osvaldo, primary, Ciudad, Laura, primary, Agirre, Xabier, primary, Pisano, David G., primary, Valencia, Alfonso, primary, Roman-Gomez, Jose, primary, Calasanz, Maria Jose, primary, Prosper, Felipe, primary, Esteller, Manel, primary, Gonzalez-Sarmiento, Rogelio, primary, and Ballestar, Esteban, primary

Published
2023
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4. Supplementary Figures 1-3, Tables 1-2 from Long-Range Epigenetic Silencing Associates with Deregulation of Ikaros Targets in Colorectal Cancer Cells

Author

Javierre, Biola M., primary, Rodriguez-Ubreva, Javier, primary, Al-Shahrour, Fatima, primary, Corominas, Marina, primary, Graña, Osvaldo, primary, Ciudad, Laura, primary, Agirre, Xabier, primary, Pisano, David G., primary, Valencia, Alfonso, primary, Roman-Gomez, Jose, primary, Calasanz, Maria Jose, primary, Prosper, Felipe, primary, Esteller, Manel, primary, Gonzalez-Sarmiento, Rogelio, primary, and Ballestar, Esteban, primary

Published
2023
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10. RAB7 Controls Melanoma Progression by Exploiting a Lineage-Specific Wiring of the Endolysosomal Pathway

Author

Alonso-Curbelo, Direna, Riveiro-Falkenbach, Erica, Pérez-Guijarro, Eva, Cifdaloz, Metehan, Karras, Panagiotis, Osterloh, Lisa, Megías, Diego, Cañón, Estela, Calvo, Tonantzin G., Olmeda, David, Gómez-López, Gonzalo, Graña, Osvaldo, Sánchez-Arévalo Lobo, Víctor Javier, Pisano, David G., Wang, Hao-Wei, Ortiz-Romero, Pablo, Tormo, Damià, Hoek, Keith, Rodríguez-Peralto, José L., Joyce, Johanna A., and Soengas, María S.

Published
2014
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11. PLCG1 mutations in cutaneous T-cell lymphomas

Author

Vaqué, José P., Gómez-López, Gonzalo, Monsálvez, Verónica, Varela, Ignacio, Martínez, Nerea, Pérez, Cristina, Domínguez, Orlando, Graña, Osvaldo, Rodríguez-Peralto, José L., Rodríguez-Pinilla, Socorro M., González-Vela, Carmen, Rubio-Camarillo, Miriam, Martín-Sánchez, Esperanza, Pisano, David G., Papadavid, Evangelia, Papadaki, Theodora, Requena, Luis, García-Marco, José A., Méndez, Miriam, Provencio, Mariano, Hospital, Mercedes, Suárez-Massa, Dolores, Postigo, Concepción, San Segundo, David, López-Hoyos, Marcos, Ortiz-Romero, Pablo L., Piris, Miguel A., and Sánchez-Beato, Margarita

Published
2014
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12. Current Efforts to Integrate Biological Pathway Information

Author

Glez-Peña, Daniel, Domínguez, Rubén, Gómez-López, Gonzalo, Pisano, David G., Fdez-Riverola, Florentino, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Omatu, Sigeru, editor, Rocha, Miguel P., editor, Bravo, José, editor, Fernández, Florentino, editor, Corchado, Emilio, editor, Bustillo, Andrés, editor, and Corchado, Juan M., editor

Published
2009
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14. Differential Gene Expression of Medullary Thyroid Carcinoma Reveals Specific Markers Associated with Genetic Conditions

Author

Maliszewska, Agnieszka, Leandro-Garcia, Luis J., Castelblanco, Esmeralda, Macià, Anna, de Cubas, Aguirre, Goméz-López, Gonzalo, Inglada-Pérez, Lucía, Álvarez-Escolá, Cristina, De la Vega, Leticia, Letón, Rocío, Gómez-Graña, Álvaro, Landa, Iñigo, Cascón, Alberto, Rodríguez-Antona, Cristina, Borrego, Salud, Zane, Mariangela, Schiavi, Francesca, Merante-Boschin, Isabella, Pelizzo, Maria R., Pisano, David G., Opocher, Giuseppe, Matias-Guiu, Xavier, Encinas, Mario, and Robledo, Mercedes

Published
2013
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16. Distinct DNA methylomes of newborns and centenarians

Author

Heyn, Holger, Li, Ning, Ferreira, Humberto J., Moran, Sebastian, Pisano, David G., Gomez, Antonio, Diez, Javier, Sanchez-Mut, Jose V., Setien, Fernando, Carmona, F. Javier, Puca, Annibale A., Sayols, Sergi, Pujana, Miguel A., Serra-Musach, Jordi, Iglesias-Platas, Isabel, Formiga, Francesc, Fernandez, Agustin F., Fraga, Mario F., Heath, Simon C., Valencia, Alfonso, Gut, Ivo G., Wang, Jun, and Esteller, Manel

Published
2012

17. PathJam: a new service for integrating biological pathway information

Author

Glez-Peña Daniel, Reboiro-Jato Miguel, Domínguez Rubén, Gómez-López Gonzalo, Pisano David G., and Fdez-Riverola Florentino

Subjects
Biotechnology, TP248.13-248.65
Abstract

Biological pathways are crucial to much of the scientific research today including the study of specific biological processes related with human diseases. PathJam is a new comprehensive and freely accessible web-server application integrating scattered human pathway annotation from several public sources. The tool has been designed for both (i) being intuitive for wet-lab users providing statistical enrichment analysis of pathway annotations and (ii) giving support to the development of new integrative pathway applications. PathJam’s unique features and advantages include interactive graphs linking pathways and genes of interest, downloadable results in fully compatible formats, GSEA compatible output files and a standardized RESTful API.

Published
2010
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18. miRNA expression in diffuse large B-cell lymphoma treated with chemoimmunotherapy

Author

Montes-Moreno, Santiago, Martinez, Nerea, Sanchez-Espiridión, Beatriz, Díaz Uriarte, Ramon, Rodriguez, Maria Elena, Saez, Anabel, Montalbán, Carlos, Gomez, Gonzalo, Pisano, David G., García, Juan Fernando, Conde, Eulogio, Gonzalez-Barca, Eva, Lopez, Andres, Mollejo, Manuela, Grande, Carlos, Martinez, Miguel Angel, Dunphy, Cherie, Hsi, Eric D., Rocque, Gabrielle B., Chang, Julie, Go, Ronald S., Visco, Carlo, Xu-Monette, Zijun, Young, Ken H., and Piris, Miguel A.

Published
2011
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20. Non-coding recurrent mutations in chronic lymphocytic leukaemia

Author

Puente, Xose S., Beà, Silvia, Valdés-Mas, Rafael, Villamor, Neus, Gutiérrez-Abril, Jesús, Martín-Subero, José I., Munar, Marta, Rubio-Pérez, Carlota, Jares, Pedro, Aymerich, Marta, Baumann, Tycho, Beekman, Renée, Belver, Laura, Carrio, Anna, Castellano, Giancarlo, Clot, Guillem, Colado, Enrique, Colomer, Dolors, Costa, Dolors, Delgado, Julio, Enjuanes, Anna, Estivill, Xavier, Ferrando, Adolfo A., Gelpí, Josep L., González, Blanca, González, Santiago, González, Marcos, Gut, Marta, Hernández-Rivas, Jesús M., López-Guerra, Mónica, Martín-García, David, Navarro, Alba, Nicolás, Pilar, Orozco, Modesto, Payer, Ángel R., Pinyol, Magda, Pisano, David G., Puente, Diana A., Queirós, Ana C., Quesada, Víctor, Romeo-Casabona, Carlos M., Royo, Cristina, Royo, Romina, Rozman, María, Russiñol, Nuria, Salaverría, Itziar, Stamatopoulos, Kostas, Stunnenberg, Hendrik G., Tamborero, David, Terol, María J., Valencia, Alfonso, López-Bigas, Nuria, Torrents, David, Gut, Ivo, López-Guillermo, Armando, López-Otín, Carlos, and Campo, Elías

Published
2015
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24. A Braf kinase-inactive mutant induces lung adenocarcinoma

Author

Nieto, Patricia, Ambrogio, Chiara, Esteban-Burgos, Laura, Gmez-Lpez, Gonzalo, Blasco, Mara Teresa, Yao, Zhan, Marais, Richard, Rosen, Neal, Chiarle, Roberto, Pisano, David G., Barbacid, Mariano, and Santamara, David

Subjects
Lung cancer -- Genetic aspects, Phosphotransferases -- Health aspects, Gene mutation -- Health aspects, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): Patricia Nieto [1]; Chiara Ambrogio [1]; Laura Esteban-Burgos [1]; Gonzalo Gmez-Lpez [2]; Mara Teresa Blasco [1]; Zhan Yao [3]; Richard Marais [4]; Neal Rosen [3]; Roberto Chiarle [5]; David [...]

Published
2017
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28. Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

Author

Puente, Xose S., Pinyol, Magda, Quesada, Víctor, Conde, Laura, Ordóñez, Gonzalo R., Villamor, Neus, Escaramis, Georgia, Jares, Pedro, Beà, Sílvia, González-Díaz, Marcos, Bassaganyas, Laia, Baumann, Tycho, Juan, Manel, López-Guerra, Mónica, Colomer, Dolors, Tubío, José M. C., López, Cristina, Navarro, Alba, Tornador, Cristian, Aymerich, Marta, Rozman, María, Hernández, Jesús M., Puente, Diana A., Freije, José M. P., Velasco, Gloria, Gutiérrez-Fernández, Ana, Costa, Dolors, Carrió, Anna, Guijarro, Sara, Enjuanes, Anna, Hernández, Lluís, Yagüe, Jordi, Nicolás, Pilar, Romeo-Casabona, Carlos M., Himmelbauer, Heinz, Castillo, Ester, Dohm, Juliane C., de Sanjosé, Silvia, Piris, Miguel A., de Alava, Enrique, Miguel, Jesús San, Royo, Romina, Gelpí, Josep L., Torrents, David, Orozco, Modesto, Pisano, David G., Valencia, Alfonso, Guigó, Roderic, Bayés, Mónica, Heath, Simon, Gut, Marta, Klatt, Peter, Marshall, John, Raine, Keiran, Stebbings, Lucy A., Futreal, Andrew P., Stratton, Michael R., Campbell, Peter J., Gut, Ivo, López-Guillermo, Armando, Estivill, Xavier, Montserrat, Emili, López-Otín, Carlos, and Campo, Elías

Published
2011
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30. Assessment of copy number variation using the Illumina Infinium 1M SNP-array: a comparison of methodological approaches in the Spanish Bladder Cancer/EPICURO study

Author

Marenne, Gaëlle, Rodríguez-Santiago, Benjamín, Closas, Montserrat García, Pérez-Jurado, Luis, Rothman, Nathaniel, Rico, Daniel, Pita, Guillermo, Pisano, David G., Kogevinas, Manolis, Silverman, Debra T., Valencia, Alfonso, Real, Francisco X., Chanock, Stephen J., Génin, Emmanuelle, and Malats, Núria

Published
2011
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32. Research Resource: Transcriptional Profiling Reveals Different Pseudohypoxic Signatures in SDHB and VHL-Related Pheochromocytomas

Author

López-Jiménez, Elena, Gómez-López, Gonzalo, Leandro-García, L. Javier, Muñoz, Iván, Schiavi, Francesca, Montero-Conde, Cristina, de Cubas, Aguirre A., Ramires, Ricardo, Landa, Iñigo, Leskelä, Susanna, Maliszewska, Agnieszka, Inglada-Pérez, Lucía, de la Vega, Leticia, Rodríguez-Antona, Cristina, Letón, Rocío, Bernal, Carmen, de Campos, José M., Diez-Tascón, Cristina, Fraga, Mario F., Boullosa, Cesar, Pisano, David G., Opocher, Giuseppe, Robledo, Mercedes, and Cascón, Alberto

Published
2010

33. The EMBRACE web service collection

Author

Pettifer, Steve, Ison, Jon, Kalaš, Matúš, Thorne, Dave, McDermott, Philip, Jonassen, Inge, Liaquat, Ali, Fernández, José M., Rodriguez, Jose M., Partners, INB-, Pisano, David G., Blanchet, Christophe, Uludag, Mahmut, Rice, Peter, Bartaseviciute, Edita, Rapacki, Kristoffer, Hekkelman, Maarten, Sand, Olivier, Stockinger, Heinz, Clegg, Andrew B., Bongcam-Rudloff, Erik, Salzemann, Jean, Breton, Vincent, Attwood, Teresa K., Cameron, Graham, and Vriend, Gert

Published
2010
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35. CNV assessment using the Illumina Infinium 1M platform: Agreement according to algorithm and source of DNA

Author

Marenne, Gaëlle, Chanock, Stephen, Rothman, Nathaniel, Rodríguez-Santiago, Benjamín, Rico, Daniel, Pita, Guillermo, Pérez-Jurado, Luis, Valencia, Alfonso, Jacobs, Kevin, Pisano, David G., Díaz-Uriarte, Ramón, Earl, Julie, García-Closas, Montserrat, Silverman, Debra, Kogevinas, Manolis, Génin, Emmanuelle, Real, Francisco X, and Malats, Núria

Published
2009
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38. Genome-wide analysis of Pax8 binding provides new insights into thyroid functions

Author

Ruiz-Llorente Sergio, de Pau Enrique Carrillo, Sastre-Perona Ana, Montero-Conde Cristina, Gómez-López Gonzalo, Fagin James A, Valencia Alfonso, Pisano David G, and Santisteban Pilar

Subjects
Pax8, ChIP-Seq, Expression arrays, CpG island, CTCF, SP1, Biotechnology, TP248.13-248.65, Genetics, QH426-470
Abstract

Abstract Background The transcription factor Pax8 is essential for the differentiation of thyroid cells. However, there are few data on genes transcriptionally regulated by Pax8 other than thyroid-related genes. To better understand the role of Pax8 in the biology of thyroid cells, we obtained transcriptional profiles of Pax8-silenced PCCl3 thyroid cells using whole genome expression arrays and integrated these signals with global cis-regulatory sequencing studies performed by ChIP-Seq analysis Results Exhaustive analysis of Pax8 immunoprecipitated peaks demonstrated preferential binding to intragenic regions and CpG-enriched islands, which suggests a role of Pax8 in transcriptional regulation of orphan CpG regions. In addition, ChIP-Seq allowed us to identify Pax8 partners, including proteins involved in tertiary DNA structure (CTCF) and chromatin remodeling (Sp1), and these direct transcriptional interactions were confirmed in vivo. Moreover, both factors modulate Pax8-dependent transcriptional activation of the sodium iodide symporter (Nis) gene promoter. We ultimately combined putative and novel Pax8 binding sites with actual target gene expression regulation to define Pax8-dependent genes. Functional classification suggests that Pax8-regulated genes may be directly involved in important processes of thyroid cell function such as cell proliferation and differentiation, apoptosis, cell polarity, motion and adhesion, and a plethora of DNA/protein-related processes. Conclusion Our study provides novel insights into the role of Pax8 in thyroid biology, exerted through transcriptional regulation of important genes involved in critical thyrocyte processes. In addition, we found new transcriptional partners of Pax8, which functionally cooperate with Pax8 in the regulation of thyroid gene transcription. Besides, our data demonstrate preferential location of Pax8 in non-promoter CpG regions. These data point to an orphan CpG island-mediated mechanism that represents a novel role of Pax8 in the transcriptional output of the thyrocyte.

Published
2012
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39. PileLine: a toolbox to handle genome position information in next-generation sequencing studies

Author

Fdez-Riverola Florentino, Reboiro-Jato Miguel, Gómez-López Gonzalo, Glez-Peña Daniel, and Pisano David G

Subjects
Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5
Abstract

Abstract Background Genomic position (GP) files currently used in next-generation sequencing (NGS) studies are always difficult to manipulate due to their huge size and the lack of appropriate tools to properly manage them. The structure of these flat files is based on representing one line per position that has been covered by at least one aligned read, imposing significant restrictions from a computational performance perspective. Results PileLine implements a flexible command-line toolkit providing specific support to the management, filtering, comparison and annotation of GP files produced by NGS experiments. PileLine tools are coded in Java and run on both UNIX (Linux, Mac OS) and Windows platforms. The set of tools comprising PileLine are designed to be memory efficient by performing fast seek on-disk operations over sorted GP files. Conclusions Our novel toolbox has been extensively tested taking into consideration performance issues. It is publicly available at http://sourceforge.net/projects/pilelinetools under the GNU LGPL license. Full documentation including common use cases and guided analysis workflows is available at http://sing.ei.uvigo.es/pileline.

Published
2011
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40. Whole genome analysis of p38 SAPK-mediated gene expression upon stress

Author

Lopez-Bigas Nuria, Pisano David G, Domínguez Orlando, Lombardía Luís, Barragan Montserrat, Gomez-Lopez Gonzalo, Islam Abul, Joaquin Manel, Ferreiro Isabel, Nebreda Angel R, and Posas Francesc

Subjects
Biotechnology, TP248.13-248.65, Genetics, QH426-470
Abstract

Abstract Background Cells have the ability to respond and adapt to environmental changes through activation of stress-activated protein kinases (SAPKs). Although p38 SAPK signalling is known to participate in the regulation of gene expression little is known on the molecular mechanisms used by this SAPK to regulate stress-responsive genes and the overall set of genes regulated by p38 in response to different stimuli. Results Here, we report a whole genome expression analyses on mouse embryonic fibroblasts (MEFs) treated with three different p38 SAPK activating-stimuli, namely osmostress, the cytokine TNFα and the protein synthesis inhibitor anisomycin. We have found that the activation kinetics of p38α SAPK in response to these insults is different and also leads to a complex gene pattern response specific for a given stress with a restricted set of overlapping genes. In addition, we have analysed the contribution of p38α the major p38 family member present in MEFs, to the overall stress-induced transcriptional response by using both a chemical inhibitor (SB203580) and p38α deficient (p38α-/-) MEFs. We show here that p38 SAPK dependency ranged between 60% and 88% depending on the treatments and that there is a very good overlap between the inhibitor treatment and the ko cells. Furthermore, we have found that the dependency of SAPK varies depending on the time the cells are subjected to osmostress. Conclusions Our genome-wide transcriptional analyses shows a selective response to specific stimuli and a restricted common response of up to 20% of the stress up-regulated early genes that involves an important set of transcription factors, which might be critical for either cell adaptation or preparation for continuous extra-cellular changes. Interestingly, up to 85% of the up-regulated genes are under the transcriptional control of p38 SAPK. Thus, activation of p38 SAPK is critical to elicit the early gene expression program required for cell adaptation to stress.

Published
2010
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42. Somatic Embryonic FGFR2 Mutations in Keratinocytic Epidermal Nevi

Author

Toll, Agustí, Fernández, Luis C., Pons, Tirso, Groesser, Leopold, Sagrera, Ana, Carrillo-de Santa Pau, Enrique, Vicente, Asunción, Baselga, Eulàlia, Vázquez, Miguel, Beltrán, Sergi, Pisano, David G., Rueda, Daniel, Gut, Marta, Pujol, Ramon M., Hafner, Christian, Gut, Ivo, Valencia, Alfonso, and Real, Francisco X.

Published
2016
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46. Comparative analysis of neutrophil and monocyte epigenomes

Author

Rico, Daniel, primary, Martens, Joost HA, additional, Downes, Kate, additional, Carrillo-de-Santa-Pau, Enrique, additional, Pancaldi, Vera, additional, Breschi, Alessandra, additional, Richardson, David, additional, Heath, Simon, additional, Saeed, Sadia, additional, Frontini, Mattia, additional, Chen, Lu, additional, Watt, Stephen, additional, Müller, Fabian, additional, Clarke, Laura, additional, Kerstens, Hindrik HD, additional, Wilder, Steven P, additional, Palumbo, Emilio, additional, Djebali, Sarah, additional, Raineri, Emanuele, additional, Merkel, Angelika, additional, Esteve-Codina, Anna, additional, Sultan, Marc, additional, van Bommel, Alena, additional, Gut, Marta, additional, Yaspo, Marie-Laure, additional, Rubio, Miriam, additional, Fernandez, José María, additional, Attwood, Anthony, additional, de la Torre, Victor, additional, Royo, Romina, additional, Fragkogianni, Stamatina, additional, Gelpí, Josep Lluis, additional, Torrents, David, additional, Iotchkova, Valentina, additional, Logie, Colin, additional, Aghajanirefah, Ali, additional, Singh, Abhishek A, additional, Janssen-Megens, Eva M, additional, Berentsen, Kim, additional, Erber, Wendy, additional, Rendon, Augusto, additional, Kostadima, Myrto, additional, Loos, Remco, additional, van der Ent, Martijn A, additional, Kaan, Anita, additional, Sharifi, Nilofar, additional, Paul, Dirk S, additional, Ifrim, Daniela C, additional, Quintin, Jessica, additional, Love, Michael I., additional, Pisano, David G, additional, Burden, Frances, additional, Foad, Nicola, additional, Farrow, Samantha, additional, Zerbino, Daniel R, additional, Dunham, Ian, additional, Kuijpers, Tacow, additional, Lehrach, Hans, additional, Lengauer, Thomas, additional, Bertone, Paul, additional, Netea, Mihai G, additional, Vingron, Martin, additional, Beck, Stephan, additional, Flicek, Paul, additional, Gut, Ivo, additional, Ouwehand, Willem H, additional, Bock, Christoph, additional, Soranzo, Nicole, additional, Guigo, Rodericw, additional, Valencia, Alfonso, additional, and Stunnenberg, Hendrik G, additional

Published
2017
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47. The EMBRACE web service collection

Author

Pettifer, Steve, Ison, Jon, Kalaš, Mat�š, Thorne, Dave, McDermott, Philip, Jonassen, Inge, Liaquat, Ali, Fern�ndez, Jos� M., Rodriguez, Jose M., Partners, INB, Pisano, David G., Blanchet, Christophe, Uludag, Mahmut, Rice, Peter, Bartaseviciute, Edita, Rapacki, Kristoffer, Hekkelman, Maarten, Sand, Olivier, Stockinger, Heinz, Clegg, Andrew B., Bongcam-Rudloff, Erik, Salzemann, Jean, Breton, Vincent, Attwood, Teresa K., Cameron, Graham, Vriend, Gert, Pettifer, Steve, Ison, Jon, Kalaš, Mat�š, Thorne, Dave, McDermott, Philip, Jonassen, Inge, Liaquat, Ali, Fern�ndez, Jos� M., Rodriguez, Jose M., Partners, INB, Pisano, David G., Blanchet, Christophe, Uludag, Mahmut, Rice, Peter, Bartaseviciute, Edita, Rapacki, Kristoffer, Hekkelman, Maarten, Sand, Olivier, Stockinger, Heinz, Clegg, Andrew B., Bongcam-Rudloff, Erik, Salzemann, Jean, Breton, Vincent, Attwood, Teresa K., Cameron, Graham, and Vriend, Gert

Abstract

The EMBRACE (European Model for Bioinformatics Research and Community Education) web service collection is the culmination of a 5-year project that set out to investigate issues involved in developing and deploying web services for use in the life sciences. The project concluded that in order for web services to achieve widespread adoption, standards must be defined for the choice of web service technology, for semantically annotating both service function and the data exchanged, and a mechanism for discovering services must be provided. Building on this, the project developed: EDAM, an ontology for describing life science web services; BioXSD, a schema for exchanging data between services; and a centralized registry (http://www.embraceregistry.net) that collects together around 1000 services developed by the consortium partners. This article presents the current status of the collection and its associated recommendations and standards definitions

Published
2017

48. The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer

Author

Fernandez, Agustin F., Rosales, Cecilia, Lopez-Nieva, Pilar, Grana, Osvaldo, Ballestar, Esteban, Ropero, Santiago, Espada, Jesus, Melo, Sonia A., Lujambio, Amaia, Fraga, Mario F, Pino, Irene, Javierre, Biola, Carmona, Francisco J., Acquadro, Francesco, Steenbergen, Renske D.M., Snijders, Peter J.F., Meijer, Chris J., Pineau, Pascal, Dejean, Anne, Lloveras, Belen, Capella, Gabriel, Quer, Josep, Buti, Maria, Esteban, Juan-Ignacio, Allende, Helena, Rodriguez-Frias, Francisco, Castellsague, Xavier, Minarovits, Janos, Ponce, Jordi, Capello, Daniela, Gaidano, Gianluca, Cigudosa, Juan Cruz, Gomez-Lopez, Gonzalo, Pisano, David G., Valencia, Alfonso, Angel Piris, Miguel, Bosch, Francesc X., Cahir-McFarland, Ellen, Kieff, Elliott, and Esteller, Manel

Subjects
Nucleotide sequence -- Analysis, Methylation -- Analysis, Cancer -- Genetic aspects, Cancer -- Research, DNA viruses -- Research, Health
Published
2009

49. Erratum to: The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies

Author

Earl, Julie, primary, Rico, Daniel, additional, Carrillo-de-Santa-Pau, Enrique, additional, Rodríguez-Santiago, Benjamín, additional, Méndez-Pertuz, Marinela, additional, Auer, Herbert, additional, Gómez, Gonzalo, additional, Grossman, H. Barton, additional, Pisano, David G., additional, Schulz, Wolfgang A., additional, Pérez-Jurado, Luis A., additional, Carrato, Alfredo, additional, Theodorescu, Dan, additional, Chanock, Stephen, additional, Valencia, Alfonso, additional, and Real, Francisco X., additional

Published
2016
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