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24. Assisted reproduction in endometriosis

Author

de Ziegler, Dominique, Pirtea, Paul, Carbonnel, Marie, Poulain, Marine, Cicinelli, Ettore, Bulletti, Carlo, Kostaras, Konstantinos, Kontopoulos, George, Keefe, David, and Ayoubi, Jean Marc

Published
2019
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25. The Impact of Conservative Surgical Treatment of Adenomyosis on Fertility and Perinatal Outcomes.

Author

Moawad, Gaby, Youssef, Youssef, Fruscalzo, Arrigo, Faysal, Hani, Merida, Manuel, Pirtea, Paul, Guani, Benedetta, Ayoubi, Jean Marc, and Feki, Anis

Subjects
FERTILITY, ENDOMETRIOSIS, HUMAN fertility, CONSERVATIVE treatment, UTERINE rupture, FERTILITY preservation, VAGINAL birth after cesarean
Abstract

Adenomyosis is a benign condition commonly encountered in patients with infertility. While the definitive surgical management is hysterectomy, conservative surgical management is gaining attention in patients desiring future fertility. This review explores whether the surgical treatment of adenomyosis affects fertility outcomes for patients trying to conceive. The PubMed and Medline databases were searched using the keywords: "adenomyosis", "surgery", "radiofrequency", "infertility", "pregnancy", "sterility", "conception", "miscarriage", and "endometrial receptivity". Abstracts were screened, and relevant articles were selected for review. This review reveals that surgery appears to improve fertility outcomes with or without medical therapy; however, the risk of uterine rupture remains high and the best technique to reduce this risk is still not known. More studies are needed to formulate the best surgical approach for preserving fertility in treating adenomyosis and to establish standardized guidelines. [ABSTRACT FROM AUTHOR]

Published
2024
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30. Adenomyosis: An Updated Review on Diagnosis and Classification

Author

Moawad, Gaby, primary, Fruscalzo, Arrigo, additional, Youssef, Youssef, additional, Kheil, Mira, additional, Tawil, Tala, additional, Nehme, Jimmy, additional, Pirtea, Paul, additional, Guani, Benedetta, additional, Afaneh, Huda, additional, Ayoubi, Jean Marc, additional, and Feki, Anis, additional

Published
2023
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33. Hiding in plain sight

Author

Pirtea, Paul, primary, De Ziegler, Dominique, additional, Toner, James, additional, Scott, Richard, additional, and Ayoubi, Jean-Marc, additional

Published
2023
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36. Recurrent implantation failure: reality or a statistical mirage? Consensus statement from the July 1, 2022 Lugano Workshop on recurrent implantation failure.

Author

Ata, Mustafa Barış (ORCID 0000-0003-1106-3747 & YÖK ID 182910), Pirtea, Paul; Cedars, Marcelle I.; Devine, Kate; Franasiak, Jason; Racowsky, Catherine; Toner, Jim; Scott, Richard T.; de Ziegler, Dominique; Barnhart, Kurt T., School of Medicine, Ata, Mustafa Barış (ORCID 0000-0003-1106-3747 & YÖK ID 182910), Pirtea, Paul; Cedars, Marcelle I.; Devine, Kate; Franasiak, Jason; Racowsky, Catherine; Toner, Jim; Scott, Richard T.; de Ziegler, Dominique; Barnhart, Kurt T., and School of Medicine

Abstract

Importance: to date, recurrent implantation failure (RIF) has no clear definition and no clearly identified impaired function. Hence, the term RIF is currently used somewhat haphazardly, on the basis of clinicians’ judgment. Objective: international experts in reproductive medicine met on July 1, 2022, in Lugano, Switzerland, to review the different facets of RIF and define the diagnosis and its appropriate management. Evidence Review: a systematic review without meta-analysis of studies published in English from January 2015 to May 2022. Findings: data indicated that RIF has been largely overevaluated, overdiagnosed, and overtreated without sufficient critical assessment of its true nature. Our analyses show that true RIF is extremely uncommon—occurring in <5% of couples with infertility—and that reassurance and continued conventional therapies are warranted in most cases of assisted reproductive technology (ART) failure. Although the true biologic determinants of RIF may exist in a small subset of people with infertility, they elude the currently available tools for assessment. Without identification of the true underlying etiology(ies), it is reasonable not to assign this diagnosis to a patient until she has failed at least 3 euploid blastocyst transfers (or the equivalent number of unscreened embryo transfers, adjusted to the patient’s age and corresponding euploidy rate). In addition, other factors should be ruled out that may contribute to her reduced odds of sustained implantation. In such cases, implantation failure should not be the only issue considered in case of ART failure because this may result from multiple other factors that are not necessarily repetitive or persistent. In reality, RIF impacting the probability of further ART success is a very rare occurrence. Conclusion: true RIF is extremely uncommon, occurring in <5% of couples with infertility. Reassurance and continued conventional therapies are warranted in most cases. It would seem reasonable, NA

Published
2023

46. Case Report: Post-Partum SARS-CoV-2 Infection After the First French Uterus Transplantation

Author

Ayoubi, Jean Marc, primary, Carbonnel, Marie, additional, Kvarnström, Niclas, additional, Revaux, Aurelie, additional, Poulain, Marine, additional, Vanlieferinghen, Sarah, additional, Coatantiec, Yves, additional, Le Marchand, Mathilde, additional, Tourne, Morgan, additional, Pirtea, Paul, additional, Snanoudj, Renaud, additional, Le Guen, Morgan, additional, Dahm-Kähler, Pernilla, additional, Racowsky, Catherine, additional, and Brännström, Mats, additional

Published
2022
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