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23 results on '"Piras, M. R."'

2. Common issues in the management of patients in the waiting list and after liver transplantation

Author

Burra, P, Belli, L, Ginanni, Corradini, S, Volpes, R, Marzioni, M, Giannini, E, Toniutto, P, Carrai, P, Donato, F, Lanza-Galeota, A, Martini, S, Pasulo, L, Ponziani, F, Russo, F, Coppola, C, Forte, P, Mazzarelli, C, Merli, M, Montalbano, M, Picciotto, F, Rendina, M, Zanetto, A, Angeli, P, Foschi, F, Manini, M, Marzano, A, Perricone, G, Pianta, P, Tamè, M, De Maria, N, Domenicali, M, Ottobrelli, A, Picciotto, A, Ponti, L, Vizzini, G, Corradini, S, Bhoori, S, Ferri, F, Gaffuri, G, Lenci, I, Mameli, L, Morelli, M, and Piras, M. R.

Subjects
medicine.medical_specialty, Alcoholic liver disease, DAAs, HBV recurrence, Immunosuppression, Liver transplantation, Antiviral Agents, Hepatitis C, Chronic, Humans, Italy, Liver Diseases, Alcoholic, Recurrence, Societies, Medical, Disease Management, Liver Transplantation, Waiting Lists, Hepatology, Gastroenterology, medicine.medical_treatment, 030230 surgery, 03 medical and health sciences, 0302 clinical medicine, Medical, Internal medicine, medicine, In patient, Chronic, Disease management (health), business.industry, Liver Diseases, General surgery, Hcv recurrence, Evidence-based medicine, Alcoholic, medicine.disease, Hepatitis C, surgical procedures, operative, Waiting list, 030211 gastroenterology & hepatology, Societies, business
Abstract

The present document contains the recommendations of an expert panel of transplant hepatologists, appointed by the Italian Association for the Study of the Liver (AISF), on how to manage the most common aspects of liver transplantation: the topics covered include: new treatments for HCV in patients on the waiting list for liver transplantation; antiviral treatments in patients with HCV recurrence after liver transplantation; prophylaxis for HBV recurrence after liver transplantation; indications for liver transplantation in alcoholic liver disease; and Immunosuppressive therapy. The statements on each topic were approved by participants at the AISF Transplant Hepatologist Expert Meeting (organized by the Permanent Committee on Liver Transplantation in Mondello on 4–5 October 2015), and are graded according to the Oxford classification of levels of evidence.

Published
2017

6. Characterization of Memory Profile in Subjects with Amnestic Mild Cognitive Impairment

Author

Perri R., Carlesimo G. A., Serra L., Caltagirone C., Alberoni M., Appollonio I., Bonaiuto S., Bottini G., Caffarra P., Carlomagno S., Carolei A., De Bastiani P., Di Luca M., Franceschi M., Gallucci M., Gambina G., Ghidoni E., Girotti F., Giubilei F., Lorusso S., Marchetti C., Monastero R., Mina C., Padovani A., Perini M., Pettenati C., Piras M. R., Provinciali L., Quartarone A., Graceffa A., Senin U., Tognoni C., Zagnoni P., Grossi E., Savare R., Perri, R, Carlesimo, G, Serra, L, Caltagirone, C, Alberoni, M, Appollonio, I, Bonaiuto, S, Bottini, G, Caffarra, P, Carlomagno, S, Carolei, A, De Bastiani, P, Di Luca, M, Franceschi, M, Gallucci, M, Gambina, G, Ghidoni, E, Girotti, F, Giubilei, F, Lorusso, S, Marchetti, C, Monastero, R, Mina, C, Padovani, A, Perini, M, Pettenati, C, Piras, M, Provinciali, L, Quartarone, A, Graceffa, A, Senin, U, Tognoni, C, Zagnoni, P, Grossi, E, and Savare, R

Subjects
Male, Neuropsychological Tests, Audiology, Activities of Daily Living, 80 and over, Attention, Episodic memory, Problem Solving, Language, Aged, 80 and over, education.field_of_study, Cognitive disorder, Psychiatric Status Rating Scale, Middle Aged, Clinical Psychology, Memory, Short-Term, Neurology, Visual Perception, Neuropsychological Test, Female, Settore MED/26 - Neurologia, medicine.symptom, Alzheimer's disease, Psychology, Human, medicine.medical_specialty, Population, Form Perception, Humans, Alzheimer Disease, Aged, Mental Recall, Cognition Disorders, Memory, Psychiatric Status Rating Scales, Behavior, Amnesia, Cognition Disorder, medicine, Dementia, Memory disorder, education, MED/26 - NEUROLOGIA, Memoria, medicine.disease, Short-Term, Neurology (clinical), Neuroscience
Abstract

Different aspects of episodic long-term, short-term and implicit long-term memory were investigated in subjects who strictly fulfilled the criteria for the amnestic form of Mild Cognitive Impairment (a-MCI). Results showed normal short-term memory abilities in these subjects, while each of the episodic long-term memory indices explored showed poorer results in a-MCI subjects with respect to normal controls. Although some episodic memory functions were relatively well preserved, others appeared to have deteriorated to a level comparable to that of mild AD patients. The finding of an extensive impairment of all memory functions depending on hippocampal structures in a population with a high risk of developing dementia is strongly supportive of the hypothesis that a pure amnesic syndrome characterizes the preclinical phase of AD. Copyright © Taylor & Francis Ltd.

Published
2005

7. Italian Frontotemporal Dementia Network (FTD Group-SINDEM): sharing clinical and diagnostic procedures in Frontotemporal Dementia in Italy

Author

Borroni B., Turrone R., Galimberti D., Nacmias B., Alberici A., Benussi A., Caffarra P., Caltagirone C., Cappa S. F., Frisoni G. B., Ghidoni R., Marra C., Padovani A., Rainero I., Scarpini E., Silani V., Sorbi S., Tagliavini F., Tremolizzo L., Bruni A. C., Agosta F., Alberoni M., Appollonio I., Arighi A., Avanzi S., Baglio F., Benussi L., Bianchetti A., Binetti G., Bonanni L., Bottacchi E., Bruno G., Canevelli M., Canu E., Cerami C., Chiari A., Conti M. Z., Costa A., Costa M., Cotelli M., Cotelli M. S., Cupidi C., Daniele A., D'Anna S., de Caro M. F., De Togni L., Dell'Osa M. T., Di Stefano F., Ferrarese C., Ferrari C., Filastro F., Floris G., Franceschi M., Gennuso M., Ghidoni E., Giordana M. T., Gragnaniello D., Grimaldi L., Lanari A., Le Pira F., Lombardi G., Lorusso S., Ludovico L., Luzzi S., Magnani G., Manfredi L. G., Marano P., Marcone A., Marrosu M. G., Martorana A., Mascia M. G., Masullo C., Mauri M., Mazzone A., Mela A., Merlo P., Micheli A., Milia A., Mina C., Montella P., Mura G., Murru M. R., Nemni R., Paci C., Pantieri R., Panza F., Parnetti L., Perini M., Pettenati C., Piccininni M., Piccoli T., Pilia G., Pinessi L., Piras M. R., Realmuto S., Ricca I., Rizzetti M. C., Rozzini L., Rubino E., Sambati L., Seripa D., Siano P., Sinforiani E., Sorrentino G., Specchio L. M., Stracciari A., Susani E., Talarico G., Tartaglione B., Tessitore A., Thomas A., Tiezzi A., Tiraboschi P., Tognoni G., Tondelli M., Trebbastoni A., Turla M., Ursini F., Valluzzi F., Vista M., Zannino G., Zanusso G., Piccoli, T, B. Borroni, R. Turrone, D. Galimberti, B. Nacmia, A. Alberici, A. Benussi, P. Caffarra, C. Caltagirone, S. F. Cappa, G. B. Frisoni, R. Ghidoni, C. Marra, A. Padovani, I. Rainero, E. Scarpini, V. Silani, S. Sorbi, F. Tagliavini, L. Tremolizzo, A. C. Bruni, The FTD Group-SINDEM, Borroni, B, Turrone, R, Galimberti, D, Nacmias, B, Alberici, A, Benussi, A, Caffarra, P, Caltagirone, C, Cappa, Sf, Frisoni, Gb, Ghidoni, R, Marra, C, Padovani, A, Rainero, I, Scarpini, E, Silani, V, Sorbi, S, Tagliavini, F, Tremolizzo, L, Bruni, Ac, The FTD, Group-SINDEM, Agosta, F, Cappa, S, Frisoni, G, Bruni, A, Alberoni, M, Appollonio, I, Arighi, A, Avanzi, S, Baglio, F, Benussi, L, Bianchetti, A, Binetti, G, Bonanni, L, Bottacchi, E, Bruno, G, Canevelli, M, Canu, E, Cerami, C, Chiari, A, Conti, M, Costa, A, Costa, M, Cotelli, M, Cupidi, C, Daniele, A, D'Anna, S, de Caro, M, De Togni, L, Dell'Osa, M, Di Stefano, F, Ferrarese, C, Ferrari, C, Filastro, F, Floris, G, Franceschi, M, Gennuso, M, Ghidoni, E, Giordana, M, Gragnaniello, D, Grimaldi, L, Lanari, A, Le Pira, F, Lombardi, G, Lorusso, S, Ludovico, L, Luzzi, S, Magnani, G, Manfredi, L, Marano, P, Marcone, A, Marrosu, M, Martorana, A, Mascia, M, Masullo, C, Mauri, M, Mazzone, A, Mela, A, Merlo, P, Micheli, A, Milia, A, Mina, C, Montella, P, Mura, G, Murru, M, Nemni, R, Paci, C, Pantieri, R, Panza, F, Parnetti, L, Perini, M, Pettenati, C, Piccininni, M, Pilia, G, Pinessi, L, Piras, M, Realmuto, S, Ricca, I, Rizzetti, M, Rozzini, L, Rubino, E, Sambati, L, Seripa, D, Siano, P, Sinforiani, E, Sorrentino, G, Specchio, L, Stracciari, A, Susani, E, Talarico, G, Tartaglione, B, Tessitore, A, Thomas, A, Tiezzi, A, Tiraboschi, P, Tognoni, G, Tondelli, M, Trebbastoni, A, Turla, M, Ursini, F, Valluzzi, F, Vista, M, Zannino, G, and Zanusso, G

Subjects
Counseling, Male, medicine.medical_specialty, Neurology, Network, Frontotemporal dementia, Frontotemporal lobar degeneration, Genetics, Survey, Aged, Aged, 80 and over, Caregivers, Female, Frontotemporal Dementia, Humans, Italy, Prevalence, Community Networks, Information Dissemination, Medicine (all), 2708, Neurology (clinical), Psychiatry and Mental Health, Dermatology, ddc:616.89, Caregivers/psychology, Epidemiology, mental disorders, medicine, 80 and over, Dementia, Disease management (health), Psychiatry, MED/26 - NEUROLOGIA, Italian network, FRONTO Temporal dementia, business.industry, Frontotemporal dementia, Frontotemporal lobar degeneration, Network, Survey, Genetics, Counseling, General Medicine, Frontotemporal Dementia/diagnosis/epidemiology, medicine.disease, Clinical trial, Settore MED/26 - Neurologia, Neurosurgery, business
Abstract

In the prospect of improved disease management and future clinical trials in Frontotemporal Dementia, it is desirable to share common diagnostic procedures. To this aim, the Italian FTD Network, under the aegis of the Italian Neurological Society for Dementia, has been established. Currently, 85 Italian Centers involved in dementia care are part of the network. Each Center completed a questionnaire on the local clinical procedures, focused on (1) clinical assessment, (2) use of neuroimaging and genetics; (3) support for patients and caregivers; (4) an opinion about the prevalence of FTD. The analyses of the results documented a comprehensive clinical and instrumental approach to FTD patients and their caregivers in Italy, with about 1,000 newly diagnosed cases per year and 2,500 patients currently followed by the participating Centers. In analogy to other European FTD consortia, future aims will be devoted to collect data on epidemiology of FTD and its subtypes and to provide harmonization of procedures among Centers.

Published
2014

8. Italian Frontotemporal Dementia Network (FTD Group-SINDEM): sharing clinical and diagnostic procedures in Frontotemporal Dementia in Italy

Author

Borroni, B, Turrone, R, Galimberti, D, Nacmias, B, Alberici, A, Benussi, A, Caffarra, P, Caltagirone, C, Cappa, S, Frisoni, G, Ghidoni, R, Marra, C, Padovani, A, Rainero, I, Scarpini, E, Silani, V, Sorbi, S, Tagliavini, F, Tremolizzo, L, Bruni, A, Agosta, F, Alberoni, M, Appollonio, I, Arighi, A, Avanzi, S, Baglio, F, Benussi, L, Bianchetti, A, Binetti, G, Bonanni, L, Bottacchi, E, Bruno, G, Canevelli, M, Canu, E, Cerami, C, Chiari, A, Conti, M, Costa, A, Costa, M, Cotelli, M, Cupidi, C, Daniele, A, D'Anna, S, de Caro, M, De Togni, L, Dell'Osa, M, Di Stefano, F, Ferrarese, C, Ferrari, C, Filastro, F, Floris, G, Franceschi, M, Gennuso, M, Ghidoni, E, Giordana, M, Gragnaniello, D, Grimaldi, L, Lanari, A, Le Pira, F, Lombardi, G, Lorusso, S, Ludovico, L, Luzzi, S, Magnani, G, Manfredi, L, Marano, P, Marcone, A, Marrosu, M, Martorana, A, Mascia, M, Masullo, C, Mauri, M, Mazzone, A, Mela, A, Merlo, P, Micheli, A, Milia, A, Mina, C, Montella, P, Mura, G, Murru, M, Nemni, R, Paci, C, Pantieri, R, Panza, F, Parnetti, L, Perini, M, Pettenati, C, Piccininni, M, Piccoli, T, Pilia, G, Pinessi, L, Piras, M, Realmuto, S, Ricca, I, Rizzetti, M, Rozzini, L, Rubino, E, Sambati, L, Seripa, D, Siano, P, Sinforiani, E, Sorrentino, G, Specchio, L, Stracciari, A, Susani, E, Talarico, G, Tartaglione, B, Tessitore, A, Thomas, A, Tiezzi, A, Tiraboschi, P, Tognoni, G, Tondelli, M, Trebbastoni, A, Turla, M, Ursini, F, Valluzzi, F, Vista, M, Zannino, G, Zanusso, G, Borroni B., Turrone R., Galimberti D., Nacmias B., Alberici A., Benussi A., Caffarra P., Caltagirone C., Cappa S. F., Frisoni G. B., Ghidoni R., Marra C., Padovani A., Rainero I., Scarpini E., Silani V., Sorbi S., Tagliavini F., Tremolizzo L., Bruni A. C., Agosta F., Alberoni M., Appollonio I., Arighi A., Avanzi S., Baglio F., Benussi L., Bianchetti A., Binetti G., Bonanni L., Bottacchi E., Bruno G., Canevelli M., Canu E., Cerami C., Chiari A., Conti M. Z., Costa A., Costa M., Cotelli M., Cotelli M. S., Cupidi C., Daniele A., D'Anna S., de Caro M. F., De Togni L., Dell'Osa M. T., Di Stefano F., Ferrarese C., Ferrari C., Filastro F., Floris G., Franceschi M., Gennuso M., Ghidoni E., Giordana M. T., Gragnaniello D., Grimaldi L., Lanari A., Le Pira F., Lombardi G., Lorusso S., Ludovico L., Luzzi S., Magnani G., Manfredi L. G., Marano P., Marcone A., Marrosu M. G., Martorana A., Mascia M. G., Masullo C., Mauri M., Mazzone A., Mela A., Merlo P., Micheli A., Milia A., Mina C., Montella P., Mura G., Murru M. R., Nemni R., Paci C., Pantieri R., Panza F., Parnetti L., Perini M., Pettenati C., Piccininni M., Piccoli T., Pilia G., Pinessi L., Piras M. R., Realmuto S., Ricca I., Rizzetti M. C., Rozzini L., Rubino E., Sambati L., Seripa D., Siano P., Sinforiani E., Sorrentino G., Specchio L. M., Stracciari A., Susani E., Talarico G., Tartaglione B., Tessitore A., Thomas A., Tiezzi A., Tiraboschi P., Tognoni G., Tondelli M., Trebbastoni A., Turla M., Ursini F., Valluzzi F., Vista M., Zannino G., Zanusso G., Borroni, B, Turrone, R, Galimberti, D, Nacmias, B, Alberici, A, Benussi, A, Caffarra, P, Caltagirone, C, Cappa, S, Frisoni, G, Ghidoni, R, Marra, C, Padovani, A, Rainero, I, Scarpini, E, Silani, V, Sorbi, S, Tagliavini, F, Tremolizzo, L, Bruni, A, Agosta, F, Alberoni, M, Appollonio, I, Arighi, A, Avanzi, S, Baglio, F, Benussi, L, Bianchetti, A, Binetti, G, Bonanni, L, Bottacchi, E, Bruno, G, Canevelli, M, Canu, E, Cerami, C, Chiari, A, Conti, M, Costa, A, Costa, M, Cotelli, M, Cupidi, C, Daniele, A, D'Anna, S, de Caro, M, De Togni, L, Dell'Osa, M, Di Stefano, F, Ferrarese, C, Ferrari, C, Filastro, F, Floris, G, Franceschi, M, Gennuso, M, Ghidoni, E, Giordana, M, Gragnaniello, D, Grimaldi, L, Lanari, A, Le Pira, F, Lombardi, G, Lorusso, S, Ludovico, L, Luzzi, S, Magnani, G, Manfredi, L, Marano, P, Marcone, A, Marrosu, M, Martorana, A, Mascia, M, Masullo, C, Mauri, M, Mazzone, A, Mela, A, Merlo, P, Micheli, A, Milia, A, Mina, C, Montella, P, Mura, G, Murru, M, Nemni, R, Paci, C, Pantieri, R, Panza, F, Parnetti, L, Perini, M, Pettenati, C, Piccininni, M, Piccoli, T, Pilia, G, Pinessi, L, Piras, M, Realmuto, S, Ricca, I, Rizzetti, M, Rozzini, L, Rubino, E, Sambati, L, Seripa, D, Siano, P, Sinforiani, E, Sorrentino, G, Specchio, L, Stracciari, A, Susani, E, Talarico, G, Tartaglione, B, Tessitore, A, Thomas, A, Tiezzi, A, Tiraboschi, P, Tognoni, G, Tondelli, M, Trebbastoni, A, Turla, M, Ursini, F, Valluzzi, F, Vista, M, Zannino, G, Zanusso, G, Borroni B., Turrone R., Galimberti D., Nacmias B., Alberici A., Benussi A., Caffarra P., Caltagirone C., Cappa S. F., Frisoni G. B., Ghidoni R., Marra C., Padovani A., Rainero I., Scarpini E., Silani V., Sorbi S., Tagliavini F., Tremolizzo L., Bruni A. C., Agosta F., Alberoni M., Appollonio I., Arighi A., Avanzi S., Baglio F., Benussi L., Bianchetti A., Binetti G., Bonanni L., Bottacchi E., Bruno G., Canevelli M., Canu E., Cerami C., Chiari A., Conti M. Z., Costa A., Costa M., Cotelli M., Cotelli M. S., Cupidi C., Daniele A., D'Anna S., de Caro M. F., De Togni L., Dell'Osa M. T., Di Stefano F., Ferrarese C., Ferrari C., Filastro F., Floris G., Franceschi M., Gennuso M., Ghidoni E., Giordana M. T., Gragnaniello D., Grimaldi L., Lanari A., Le Pira F., Lombardi G., Lorusso S., Ludovico L., Luzzi S., Magnani G., Manfredi L. G., Marano P., Marcone A., Marrosu M. G., Martorana A., Mascia M. G., Masullo C., Mauri M., Mazzone A., Mela A., Merlo P., Micheli A., Milia A., Mina C., Montella P., Mura G., Murru M. R., Nemni R., Paci C., Pantieri R., Panza F., Parnetti L., Perini M., Pettenati C., Piccininni M., Piccoli T., Pilia G., Pinessi L., Piras M. R., Realmuto S., Ricca I., Rizzetti M. C., Rozzini L., Rubino E., Sambati L., Seripa D., Siano P., Sinforiani E., Sorrentino G., Specchio L. M., Stracciari A., Susani E., Talarico G., Tartaglione B., Tessitore A., Thomas A., Tiezzi A., Tiraboschi P., Tognoni G., Tondelli M., Trebbastoni A., Turla M., Ursini F., Valluzzi F., Vista M., Zannino G., and Zanusso G.

Abstract

In the prospect of improved disease management and future clinical trials in Frontotemporal Dementia, it is desirable to share common diagnostic procedures. To this aim, the Italian FTD Network, under the aegis of the Italian Neurological Society for Dementia, has been established. Currently, 85 Italian Centers involved in dementia care are part of the network. Each Center completed a questionnaire on the local clinical procedures, focused on (1) clinical assessment, (2) use of neuroimaging and genetics; (3) support for patients and caregivers; (4) an opinion about the prevalence of FTD. The analyses of the results documented a comprehensive clinical and instrumental approach to FTD patients and their caregivers in Italy, with about 1,000 newly diagnosed cases per year and 2,500 patients currently followed by the participating Centers. In analogy to other European FTD consortia, future aims will be devoted to collect data on epidemiology of FTD and its subtypes and to provide harmonization of procedures among Centers.

Published
2015

10. Characterization of memory profile in subjects with amnestic mild cognitive impairment

Author

Perri, R, Carlesimo, G, Serra, L, Caltagirone, C, Alberoni, M, Appollonio, I, Bonaiuto, S, Bottini, G, Caffarra, P, Carlomagno, S, Carolei, A, De Bastiani, P, Di Luca, M, Franceschi, M, Gallucci, M, Gambina, G, Ghidoni, E, Girotti, F, Giubilei, F, Lorusso, S, Marchetti, C, Monastero, R, Mina, C, Padovani, A, Perini, M, Pettenati, C, Piras, M, Provinciali, L, Quartarone, A, Graceffa, A, Senin, U, Tognoni, C, Zagnoni, P, Grossi, E, Savare, R, Perri R., Carlesimo G. A., Serra L., Caltagirone C., Alberoni M., Appollonio I., Bonaiuto S., Bottini G., Caffarra P., Carlomagno S., Carolei A., De Bastiani P., Di Luca M., Franceschi M., Gallucci M., Gambina G., Ghidoni E., Girotti F., Giubilei F., Lorusso S., Marchetti C., Monastero R., Mina C., Padovani A., Perini M., Pettenati C., Piras M. R., Provinciali L., Quartarone A., Graceffa A., Senin U., Tognoni C., Zagnoni P., Grossi E., Savare R., Perri, R, Carlesimo, G, Serra, L, Caltagirone, C, Alberoni, M, Appollonio, I, Bonaiuto, S, Bottini, G, Caffarra, P, Carlomagno, S, Carolei, A, De Bastiani, P, Di Luca, M, Franceschi, M, Gallucci, M, Gambina, G, Ghidoni, E, Girotti, F, Giubilei, F, Lorusso, S, Marchetti, C, Monastero, R, Mina, C, Padovani, A, Perini, M, Pettenati, C, Piras, M, Provinciali, L, Quartarone, A, Graceffa, A, Senin, U, Tognoni, C, Zagnoni, P, Grossi, E, Savare, R, Perri R., Carlesimo G. A., Serra L., Caltagirone C., Alberoni M., Appollonio I., Bonaiuto S., Bottini G., Caffarra P., Carlomagno S., Carolei A., De Bastiani P., Di Luca M., Franceschi M., Gallucci M., Gambina G., Ghidoni E., Girotti F., Giubilei F., Lorusso S., Marchetti C., Monastero R., Mina C., Padovani A., Perini M., Pettenati C., Piras M. R., Provinciali L., Quartarone A., Graceffa A., Senin U., Tognoni C., Zagnoni P., Grossi E., and Savare R.

Abstract

Different aspects of episodic long-term, short-term and implicit long-term memory were investigated in subjects who strictly fulfilled the criteria for the amnestic form of Mild Cognitive Impairment (a-MCI). Results showed normal short-term memory abilities in these subjects, while each of the episodic long-term memory indices explored showed poorer results in a-MCI subjects with respect to normal controls. Although some episodic memory functions were relatively well preserved, others appeared to have deteriorated to a level comparable to that of mild AD patients. The finding of an extensive impairment of all memory functions depending on hippocampal structures in a population with a high risk of developing dementia is strongly supportive of the hypothesis that a pure amnesic syndrome characterizes the preclinical phase of AD. Copyright © Taylor & Francis Ltd.

Published
2005

11. Clear cell hepatocellular carcinoma treated with liver transplantation

Author

Pecorella, I., Antonio Ciardi, Aiello, E., Piras, M. R., Farci, C., and Di Tondo, U.

Subjects
Adult, Carcinoma, Hepatocellular, Liver Neoplasms, Humans, Female, Adenocarcinoma, Clear Cell, Liver Transplantation
Abstract

We report a case of a 35-year-old female who underwent total hepatectomy and liver transplantation for a diffuse clear cell variant of hepatocellular carcinoma in non-cirrhotic liver. Preoperative clinical evaluation showed no extrahepatic metastatic involvement. However, scheletal metastases of the tumour were detected five months later. Although clear cell variant is generally considered to run a relatively favorable course, this case proved rapidly progressive and seems therefore to be a debatable candidate for liver transplantation among primary hepatic cancers.

Published
1994

12. A novel PSEN2 mutation associated with a peculiar phenotype

Author

Piscopo, P., primary, Marcon, G., additional, Piras, M. R., additional, Crestini, A., additional, Campeggi, L. Malvezzi, additional, Deiana, E., additional, Cherchi, R., additional, Tanda, F., additional, Deplano, A., additional, Vanacore, N., additional, Tagliavini, F., additional, Pocchiari, M., additional, Giaccone, G., additional, and Confaloni, A., additional

Published
2008
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14. A novel PSEN2mutation associated with a peculiar phenotype

Author

Piscopo, P, Marcon, G, Piras, M R., Crestini, A, Campeggi, L Malvezzi, Deiana, E, Cherchi, R, Tanda, F, Deplano, A, Vanacore, N, Tagliavini, F, Pocchiari, M, Giaccone, G, and Confaloni, A

Abstract

Mutations of presenilin 2 gene are a rare cause of familial Alzheimer disease (AD). We describe an Italian family with hereditary dementia associated with a novel mutation in the presenilin 2 gene.

Published
2008
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15. Preclinical phase of Alzheimer's disease: Guideline for recognition and study of patients with mild cognitive impairment,La fase preclinica della malattia di Alzheimer: Linee-guida per il riconoscimento e lo studio dei pazienti con 'mild cognitive impairment'

Author

Caltagirone, C., Perri, R., Musicco, M., Alberoni, M., Apollonio, I., Bonaiuto, S., Bottini, G., Caffarra, R., Carlomagno, S., Carolei, A., Cipriani, L., Di Luca, M., Bastiani, R., Franceschi, M., Frisoni, G., Gallucci, M., Gambina, G., Ghidoni, E., Girotti, F., Giubilei, F., Lorusso, S., Marchetti, C., Monastero, R., Morocutti, Padovani, A., Michele Perini, Pettenati, C., Piras, M. R., Postiglione, A., Provinciali, L., Quartarone, A., Rinaldi, A., Senin, U., Mecocci, P., Sozzi, G., Tognoni, C., Zagnoni, P., Grossi, E., and Savarè, R.

16. Italian Neurological Society guidelines for the diagnosis of dementia: Revision l

Author

Musico, M., Caltagirone, C., Sorbi, S., Bonavita, V., Alberoni, M., Alfieri, P., Altavista, M. C., Amici, S., Antana, D., ILDEBRANDO APPOLLONIO, Avanzi, S., Bartolini, M., Bergamasco, B., Blundo, C., Bonavia, V., Bonuccelli, U., Cipriani, G., Bracco, L., Bruni, A. C., Bugiani, O., Caffara, P., Perri, R., Camarda, R., Canal, N., Cannatà, A., Cantone, G., Carabelli, E., Cardei, A., Carlomagno, S., Casini, A. R., Cheldi, A., Cannnella, L., Citterio, A., Daniele, A., D Anna, S., Del Curatolo, G., Del Pesce, M., Aversana, R., Farina, E., Fasanaro, A. M., Franceschi, M., Gabriele, P., Gainotti, G., Galante, E., Gallai, V., Gallasi, R., Bambina, S., Gasparini, M., Giaccone, G., Giubilei, F., Grassi, M. P., Grimaldi, L., Grioli, S., Bianca, S. G., Guarnirei, M., Batoli, A., Jandolo, B., Temolo, F., La Stilla, M., Latino, R. R., Lenzi, G. L., Lorusso, S., Magnani, G., Malaga, S., Manfredi, L., Marcon, G., Marcore, A., Mariani, C., Mearelli, S., Minore, A., Moleri, M., Morante, M., Morbin, M., Moretti, P., Murri, L., Rognoni, G., Musicco, M., Nichelli, P., Paciello, M., Padovani, A., Paganini, M., Pantieri, R., Parisen, P., Parnetti, L., Partitico, D., Pasquale, S., Passerella, B., Perini, M., Pettinati, C., Piacentini, S., Piccoli, F., Piccolini, C., Pinardi, G., Piras, M. R., Cerchi, R., Principe, M., Provinciali, L., Pugliese, N., Musicco M., Caltagirone C., Sorbi S., Bonavita V., and Gallassi R.

Subjects
Neurologic Examination, medicine.medical_specialty, business.industry, Linee guida, Malattia di Alzheimer, Diagnosi, Demenza, Dermatology, General Medicine, medicine.disease, Psychiatry and Mental health, Italy, Neurology, Medical, mental disorders, medicine, Dementia, Humans, Settore MED/26 - Neurologia, Neurology (clinical), Psychiatry, business, Societies, Societies, Medical
Abstract

The objective of this study was to verify the adherence of Italian family physicians and neurologists to the Guidelines on Diagnosis of Dementia of the Italian Society of Neurology. A multicentre survey was carried out, in 72 neurological centres. The centres included at least 15 consecutive subjects suspected of having a dementia. The adherence of family physicians to the guidelines was poor. Neurologists performed a complete neuropsychological evaluation in a minority of the cases. Patients who had a decrease of Mini Mental Status Examination scores after six months higher than or equal to 4 were more represented among those patients for whom one or more recommendations were not respected. In Italy the adherence to the Guidelines on Diagnosis of Dementia and AlzheimerValidation studys Disease of the Italian Society of Neurology is very poor for family physicians (GPs) and satisfactory, albeit improvable, on the part of neurologists. Respect for the guidelines might improve the outcome of patients with dementia.

17. Preclinical phase of Alzheimer's disease: Guideline for recognition and study of patients with mild cognitive impairment | La fase preclinica della malattia di Alzheimer: Linee-guida per il riconoscimento e lo studio dei pazienti con 'mild cognitive impairment'

Author

Caltagirone, C., Perri, R., Musicco, M., Alberoni, M., Apollonio, I., Bonaiuto, S., Bottini, G., Caffarra, R., Carlomagno, S., Carolei, A., Cipriani, L., Di Luca, M., Bastiani, R., Franceschi, M., Frisoni, G., Gallucci, M., Gambina, G., Ghidoni, E., Girotti, F., Giubilei, F., Lorusso, S., Marchetti, C., Monastero, R., Morocutti, Padovani, A., Perini, M., Pettenati, C., Piras, M. R., Postiglione, A., Provinciali, L., Angelo QUARTARONE, Rinaldi, A., Senin, U., Mecocci, P., Sozzi, G., Tognoni, C., Zagnoni, P., Grossi, E., and Savarè, R.

18. Cognitive impairment and neurophysiological correlates in MS.

Author

Magnano I, Aiello I, and Piras MR

Subjects
Humans, Multiple Sclerosis complications, Reaction Time physiology, Cognition Disorders physiopathology, Electroencephalography, Evoked Potentials physiology, Multiple Sclerosis physiopathology
Abstract

Cognitive impairment in multiple sclerosis (MS) has received considerable interest over the last decades. Heterogeneous patterns of cognitive dysfunction have been reported in literature in relation to the subtype of the disease and the severity of specific cognitive domains affected. Event related potentials (ERPs), especially P300, have been employed to evaluate the cognitive decline in MS and neurophysiological findings agree with data obtained by neuropsychological testing. The objectivity, the reliability and the easy administration are the main features of ERP technique but more specific attention and memory tasks are needed to enhance the clinical value of the methodology. Moreover, ERP recording has the advantage of being feasible even in severe disabled patients. Finally, longitudinal ERP studies are required to investigate the natural course of cognitive dysfunction in MS, to estimate the prognostic value of subclinical defects in different clinical form of the disease and to evaluate clinical benefits of therapeutic and rehabilitative interventions.

Published
2006
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19. Visual and auditory event-related potentials in sporadic amyotrophic lateral sclerosis.

Author

Paulus KS, Magnano I, Piras MR, Solinas MA, Solinas G, Sau GF, and Aiello I

Subjects
Adult, Aged, Brain physiopathology, Cognition physiology, Event-Related Potentials, P300, Female, Humans, Male, Middle Aged, Amyotrophic Lateral Sclerosis physiopathology, Evoked Potentials, Auditory, Evoked Potentials, Visual
Abstract

Objectives: To investigate the relationship between amyotrophic lateral sclerosis (ALS) and cognitive function by means of oddball event-related potentials (ERPs) and to determine the usefulness of this methodology in the cognitive status assessment of physically disabled patients., Methods: Visual and auditory oddball ERPs were recorded in 16 consecutive sporadic ALS patients. A comprehensive battery of neuropsychological (NP) tests assessed intelligence, executive functions, attention, memory, word fluency, visuo-motor and visual-constructive skills., Results: All patients performed visual and auditory ERPs and 75% of cases showed abnormal N200 and/or P300 waves. Ten patients (62.5%) carried out the entire psychometric evaluation with significant impairment on tests of executive function and attention. A significant correlation between delayed visual (P<0.04) and auditory (P<0.04) P300 latency and impaired NP tests was found., Conclusions: In agreement with literature data, our findings confirm the hypothesis of cognitive impairment in ALS patients especially on attention and executive functions suggesting a more extensive degeneration beyond the motor areas. ALS causes severe physical disabilities and such a condition may interfere with NP testing. Thus, the P300 seems to be a useful tool for the assessment of cognition and attention when severe physical deficits are present.

Published
2002
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20. Phenobarbital-induced buccolingual dyskinesia in oral apraxia.

Author

Sechi GP, Piras MR, Rosati G, Zuddas M, Ortu R, Tanca S, and Agnetti V

Subjects
Adult, Apraxias diagnostic imaging, Apraxias drug therapy, Brain diagnostic imaging, Dyskinesia, Drug-Induced etiology, Female, Humans, Mouth Diseases etiology, Tomography, X-Ray Computed, Apraxias complications, Dyskinesia, Drug-Induced diagnosis, Phenobarbital adverse effects
Abstract

A young woman with oral apraxia and a well-defined brain lesion on CT scan developed buccolingual dyskinesia lasting 40 days after low phenobarbital (PB) doses. Disruption of the corticostriatal glutamatergic pathway from areas 6 and 4 may have been important both in causing oral apraxia and in lowering the threshold for PB-induced buccolingual dyskinesia.

Published
1988
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22. Dexamethasone-induced schizoaffective-like state in multiple sclerosis: prophylaxis and treatment with carbamazepine.

Author

Sechi GP, Piras MR, Demurtas A, Tanca S, and Rosati G

Subjects
Adult, Dexamethasone therapeutic use, Female, Humans, Psychoses, Substance-Induced drug therapy, Psychoses, Substance-Induced prevention & control, Psychotic Disorders drug therapy, Psychotic Disorders prevention & control, Carbamazepine therapeutic use, Dexamethasone adverse effects, Multiple Sclerosis drug therapy, Psychoses, Substance-Induced etiology, Psychotic Disorders etiology
Published
1987
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23. [Serum gastrin in rheumatoid arthritis].

Author

Taglieri G, Piga M, Ibba G, Piras MR, and Uras R

Subjects
Adolescent, Adult, Anti-Inflammatory Agents therapeutic use, Arthritis, Rheumatoid drug therapy, Cortisone therapeutic use, Female, Gold therapeutic use, Humans, Male, Middle Aged, Arthritis, Rheumatoid blood, Gastrins blood
Abstract

Serum gastrin concentrations under basal conditions and following stimulation were assessed in 40 patients suffering from rheumatoid arthritis (RA) and compared with healthy individuals. The RA groups showed no significant differences in comparison with the control population. These conclusions lead the authors to seek the reasons for the rare instances of confirmed hypergastrinaemia in RA.

Published
1982

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