Search

Your search keyword '"Pinto, Daniel"' showing total 1,037 results
Start Over Author "Pinto, Daniel"
1,037 results on '"Pinto, Daniel"'

1. Bubble wall velocities with an extended fluid Ansatz

Author

Dorsch, Glauber C. and Pinto, Daniel A.

Subjects
High Energy Physics - Phenomenology, High Energy Physics - Theory
Abstract

We compute the terminal bubble wall velocity during a cosmological phase transition by modelling non-equilibrium effects in the plasma with the so-called "extended fluid Ansatz". A $\phi^6$ operator is included in the Standard Model effective potential to mimic effects of new physics. Hydrodynamical heating of the plasma ahead of the bubble is taken into account. We find that the inclusion of higher order terms in the fluid Ansatz is typically relevant, and may even turn detonation solutions into deflagrations. Our results also corroborate recent findings in the literature that, for a Standard Model particle content in the plasma, only deflagration solutions are viable. However, we also show that this outcome may be altered in a theory with a different particle content., Comment: 22 pages, 8 figures

Published
2023

4. Physical activity and exercise for the prevention and management of mild cognitive impairment and dementia: a collaborative international guideline

Author

Veronese, Nicola, Soysal, Pinar, Demurtas, Jacopo, Solmi, Marco, Bruyère, Olivier, Christodoulou, Nikos, Ramalho, Rodrigo, Fusar-Poli, Paolo, Lappas, Andreas S., Pinto, Daniel, Frederiksen, Kristian Steen, Corbi, Grazia Maria, Karpenko, Olga, Georges, Jean, Durães, João, Schlögl, Mathias, Yilmaz, Ozlem, Sieber, Cornel, Shenkin, Susan D., Smith, Lee, Reginster, Jean-Yves, Maggi, Stefania, Limongi, Federica, Ars, Joan, Barbagallo, Mario, Cherubini, Antonio, and Quinn, Terry

Published
2023
Full Text
View/download PDF

8. Aspiration Techniques

Author

Pinto, Daniel Gomes, Tse, Gary, Tan, Puay-Hoon, Schmitt, Fernando, Tse, Gary, editor, Tan, Puay-Hoon, editor, and Schmitt, Fernando, editor

Published
2023
Full Text
View/download PDF

25. Corrigendum to “A randomized trial of a motivational interviewing intervention to increase lifestyle physical activity and improve self-reported function in adults with arthritis” [Seminars in Arthritis and Rheumatism 47(2018): 732–740]

Author

Gilbert, Abigail L., primary, Lee, Jungwha, additional, Ehrlich-Jones, Linda, additional, Semanik, Pamela A., additional, Song, Jing, additional, Pellegrini, Christine A., additional, Pinto, Daniel, additional, Dunlop, Dorothy D., additional, and Chang, Rowland W., additional

Published
2024
Full Text
View/download PDF

26. Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe.

Author

Cardozo Pinto, Daniel F, Yang, Hongbin, Pollak Dorocic, Iskra, de Jong, Johannes W, Han, Vivian J, Peck, James R, Zhu, Yichen, Liu, Christine, Beier, Kevin T, Smidt, Marten P, and Lammel, Stephan

Subjects
Neural Pathways, Animals, Mice, Transgenic, Mice, Neurotransmitter Agents, Models, Animal, Serotonin Plasma Membrane Transport Proteins, Dopaminergic Neurons, Serotonergic Neurons, Dorsal Raphe Nucleus, Neurosciences, 1.1 Normal biological development and functioning, Neurological, Transgenic, Models, Animal, MD Multidisciplinary
Abstract

The dorsal raphe (DR) is a heterogeneous nucleus containing dopamine (DA), serotonin (5HT), γ-aminobutyric acid (GABA) and glutamate neurons. Consequently, investigations of DR circuitry require Cre-driver lines that restrict transgene expression to precisely defined cell populations. Here, we present a systematic evaluation of mouse lines targeting neuromodulatory cells in the DR. We find substantial differences in specificity between lines targeting DA neurons, and in penetrance between lines targeting 5HT neurons. Using these tools to map DR circuits, we show that populations of neurochemically distinct DR neurons are arranged in a stereotyped topographical pattern, send divergent projections to amygdala subnuclei, and differ in their presynaptic inputs. Importantly, targeting DR DA neurons using different mouse lines yielded both structural and functional differences in the neural circuits accessed. These results provide a refined model of DR organization and support a comparative, case-by-case evaluation of the suitability of transgenic tools for any experimental application.

Published
2019

27. Hot topic in optogenetics: new implications of in vivo tissue heating

Author

Cardozo Pinto, Daniel F and Lammel, Stephan

Subjects
Biological Psychology, Biomedical and Clinical Sciences, Neurosciences, Psychology, 1.1 Normal biological development and functioning, Underpinning research, Neurological, Heating, Hot Temperature, Optogenetics, Cognitive Sciences, Neurology & Neurosurgery, Biological psychology
Abstract

In this issue of Nature Neuroscience, Owen et al. show that widely used optogenetic light delivery can heat brain tissue and produce changes in neural activity and behavior in the absence of opsins. How will this finding influence experimental design in the optical age of neuroscience?

Published
2019

28. Viral vector strategies for investigating midbrain dopamine circuits underlying motivated behaviors

Author

Pinto, Daniel F Cardozo and Lammel, Stephan

Subjects
Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Behavioral and Social Science, Neurosciences, Substance Misuse, Drug Abuse (NIDA only), Brain Disorders, Mental Health, Mental health, Neurological, Good Health and Well Being, Animals, Brain Mapping, Dopaminergic Neurons, Genetic Vectors, Humans, Magnetic Resonance Imaging, Mesencephalon, Motivation, Optogenetics, Rabies virus, Reward, Synapses, Ventral Tegmental Area, Viruses, Dopamine, Mesocorticolimbic, Aversion, Ventral tegmental area, Neurology & Neurosurgery, Pharmacology and pharmaceutical sciences
Abstract

Midbrain dopamine (DA) neurons have received significant attention in brain research because of their central role in reward processing and their dysfunction in neuropsychiatric disorders such as Parkinson's disease, drug addiction, depression and schizophrenia. Until recently, it has been thought that DA neurons form a homogeneous population whose primary function is the computation of reward prediction errors. However, through the implementation of viral vector strategies, an unexpected complexity and diversity has been revealed at the anatomical, molecular and functional level. In this review, we discuss recent viral vector approaches that have been leveraged to dissect how different circuits involving distinct DA neuron subpopulations may contribute to the role of DA in reward- and aversion-related behaviors. We focus on studies that have used cell type- and projection-specific optogenetic manipulations, discuss the strengths and limitations of each approach, and critically examine emergent organizational principles that have led to a reclassification of midbrain DA neurons.

Published
2018

31. Relationship of knee pain to time in moderate and light physical activities: Data from Osteoarthritis Initiative

Author

Song, Jing, Chang, Alison H, Chang, Rowland W, Lee, Jungwha, Pinto, Daniel, Hawker, Gillian, Nevitt, Michael, and Dunlop, Dorothy D

Subjects
Pain Research, Arthritis, Behavioral and Social Science, Chronic Pain, Osteoarthritis, Aging, Clinical Research, Musculoskeletal, Activities of Daily Living, Aged, Cross-Sectional Studies, Exercise, Female, Humans, Knee Joint, Male, Middle Aged, Osteoarthritis, Knee, Pain, Pain Measurement, Physical activity, Intermittent knee pain, Constant knee pain, Clinical Sciences, Public Health and Health Services, Arthritis & Rheumatology
Abstract

INTRODUCTION:While OA literature indicates greater pain is related to less time being physically active, it is not known if time curtailment occurs primarily for moderate intensity activities or for light activities or in both. We examine the cross-sectional association of knee pain with physical activity using data from 1874 Osteoarthritis Initiative participants. METHODS:Knee pain characteristics of constant and intermittent pain were each scored by the Intermittent and Constant Osteoarthritis Pain instrument and categorized into four pain levels (no pain, intermittent pain below and above median level, and constant pain). The relationships between knee pain levels and objectively measured physical activity (average weekly moderate or light intensity minutes) were assessed by quantile regression adjusted for socio-demographics and health factors. RESULTS:Knee pain levels had a strong negative relationship with moderate intensity physical activities (p-value for trend =0.029). Compared to the no pain group, persons with more severe knee pain, particularly those reporting higher intermittent or constant pain spent less time in moderate activity. In contrast, there was no notable trend related to pain with time spent in light intensity activity. These patterns remained when restricted to persons with clinical evidence (symptoms and/or radiographic) of knee OA and among persons not using medications for knee symptoms. CONCLUSION:Greater knee pain levels were strongly related to less moderate intensity activity time, but not time spent in light intensity physical activity. This relationship suggests that light activity may be a more acceptable way to increase physical activity than moderate activity for people with symptomatic knee pain.

Published
2018

33. Methylmercury chronic exposure affects the expression of DNA single-strand break repair genes, induces oxidative stress, and chromosomal abnormalities in young dyslipidemic APOE knockout mice

Author

Roque, Cássia R., Sampaio, Letícia R., Ito, Mayumi N., Pinto, Daniel V., Caminha, Juan S.R., Nunes, Paulo I.G., Raposo, Ramon S., Santos, Flávia A., Windmöller, Cláudia C., Crespo-Lopez, Maria Elena, Alvarez-Leite, Jacqueline I., Oriá, Reinaldo B., and Pinheiro, Ronald F.

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results