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Your search keyword '"Pino-Rosa, Silvia"' showing total 10 results
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10 results on '"Pino-Rosa, Silvia"'

1. Immunogenicity of a third dose with mRNA-vaccines in the ChAdOx1-S/BNT162b2 vaccination regimen against SARS-CoV-2 variants

Author

García, Lucía Díaz, García, Elena Ramírez, Meseguer, Enrique Seco, Stewart Balbàs, Stefan Mark, Candón, Alicia Marín, García, Irene García, Elizalde, Mikel Urroz, Rosa, Paula de la, García, Marta Sanz, Crespo, Cristina López, Martínez, Vega Mauleón, de Madariaga Castell, Raquel, Vara, Laura Vitón, Prieto-Pérez, Rocío, Vargas-Castrillón, Emilio, Laredo, Leonor, Zhu-Huang, Ouhao, Iglesias, Teresa, Imaz-Ayo, Natale, Meijide, Susana, García de Vicuña, Aitor, Santorcuato, Ana, Exposito, Iraide, de Benito, Sara, Bustinza, Alazne, Gallego, Mikel, García-Vázquez, Dolores, Belén de la Hoz, Ana, Pérez-Nanclares, Gustavo, Aurrekoetxea, Josu, Urrutia, Ines, Martínez-Salazar, Rosa, Orcajo, Janire, Calvo, Begoña, Corcuera, June, Velasco, Olaia, Aguayo, Anibal, Martínez-Gómez, Xavier, Otero-Romero, Susana, Armadans, Lluis, Borras-Bermejo, Blanca, Parés, Oleguer, Uriona, Sonia, Rodrigo Pendás, José Ángel, Llorente, Cesar, Santos, José, Pinós, Laia, Camacho, Lina, Riera, Judith, Sans, Carla, Agustí, Antonia, Altadill, Carmen, Blancafort, Carla Aguilar, Serrat, Gisela Gili, Plaza, Aitana, Prius, Anna Feliu, Torrens, Maria Margarita, Palacio, Esther, Torres, Gloria, Calonge, Julia, Alins, Elena Ballarin, Pérez-Esquirol, Eulàlia, Bosch, Lourdes Vendrell, Aldea, Marta, Mellado, Eugènia, Marcos, M<ce:sup loc='post">a</ce:sup> Ángeles, Tortajada, Marta, Barón-Mira, Lourdes E., Granés, Laura, Lazaar, Sulayman, Herranz, Sara, Malet, Montserrat, Quesada, Sebastiana, Llupià, Anna, Olivé, Victoria, Trilla, Antoni, Gómez, Begoña, González, Elisenda, Romero, Sheila, Gámez, Francisco Javier, Casals, Cristina, Burunat, Laura, Castelló, Juan José, Fernández, Patricia, Bedini, Josep Lluís, Vila, Jordi, Hurtado, Juan Carlos, Jado, Isabel, Fedele, Giovanni, Perea, Concepción, González, Mónica, Grajera, Isabel, Murillo, María Ángeles, Balfagón, Pilar, Díaz-Marín, Irene, González-Pardo, Gema, García-Pérez, Javier, Borobia, Alberto M., Pérez-Olmeda, Mayte, Portolés, Antonio, Castaño, Luis, Campins-Artí, Magdalena, Bertrán, María Jesús, Bermejo, Mercedes, Arribas, José Ramón, López, Andrea, Ascaso-del-Rio, Ana, Arana-Arri, Eunate, Fuentes Camps, Inmaculada, Vilella, Anna, Cascajero, Almudena, García-Morales, María Teresa, Castillo de la Osa, María, Pérez Ingidua, Carla, Lora, David, Jiménez-Santana, Paloma, Pino-Rosa, Silvia, Gómez de la Cámara, Agustín, De La Torre-Tarazona, Erick, Calonge, Esther, Cruces, Raquel, Belda-Iniesta, Cristóbal, Alcamí, José, Frías, Jesús, Carcas, Antonio J., and Díez-Fuertes, Francisco

Published
2024
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8. Genomic Background and Phylogeny of cfi A-Positive Bacteroides fragilis Strains Resistant to Meropenem-EDTA.

Author

Valdezate, Sylvia, Cobo, Fernando, Monzón, Sara, Medina-Pascual, María J., Zaballos, Ángel, Cuesta, Isabel, Pino-Rosa, Silvia, Villalón, Pilar, and Hassan, Karl

Subjects
BACTEROIDES fragilis, PHYLOGENY, GENES, DRUG resistance in microorganisms, ANTI-infective agents, GENOMES
Abstract

Background: Bacteroides fragilis shows high antimicrobial resistance (AMR) rates and possesses numerous AMR mechanisms. Its carbapenem-resistant strains (metallo-β-lactamase cfiA-positive) appear as an emergent, evolving clade. Methods: This work examines the genomes, taxonomy, and phylogenetic relationships with respect to other B. fragilis genomes of two B. fragilis strains (CNM20180471 and CNM20200206) resistant to meropenem+EDTA and other antimicrobial agents. Results: Both strains possessed cfiA genes (cfiA14b and the new cfiA28), along with other AMR mechanisms. The presence of other efflux-pump genes, mexAB/mexJK/mexXY-oprM, acrEF/mdtEF-tolC, and especially cusR, which reduces the entry of carbapenem via the repression of porin OprD, may be related to meropenem–EDTA resistance. None of the detected insertion sequences were located upstream of cfiA. The genomes of these and other B. fragilis strains that clustered together in phylogenetic analyses did not meet the condition of >95% average nucleotide/amino acid identity, or >70% in silico genome-to-genome hybridization similarity, to be deemed members of the same species, although <1% difference in the genomic G+C content was seen with respect to the reference genome B. fragilis NCTC 9343T. Conclusions: Carbapenem-resistant strains may be considered a distinct clonal entity, and their surveillance is recommended given the ease with which they appear to acquire AMR. [ABSTRACT FROM AUTHOR]

Published
2021
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10. Characterization of group A beta-haemolytic streptococcus with mucoid phenotype isolated in a tertiary hospital.

Author

Guzmán-Puche J, Tejero-Garcia R, Villalón P, Pino-Rosa S, and Martínez-Martínez L

Abstract

Introduction: The objective of this study is to characterize Streptococcus pyogenes isolates with a mucoid phenotype and to compare them with non-mucoid isolates obtained between April and August 2016., Material and Methods: Identification and antimicrobial susceptibility were performed in all isolates. The emm type and exotoxin genes speA, speB, speC, speF, speG, speH, speJ, speZ and ssa were analyzed. Clinical and demographic data were collected., Results: From 96 isolates analyzed, 47% had a mucoid phenotype and 95.5% of them presented speA-speB-speF-speG-ssa genes and emm3 genotype. The main clinical manifestation was pharyngotonsillitis (77.1%) evolving to scarlet fever in 67.5% of the cases., Conclusion: This study describes the circulation of a mucoid phenotype strain with a speA-speB-speF-speG-ssa toxin profile and emm3.1 genotype considered one of the most frequent and virulent of SGA., (Copyright © 2021 Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. Publicado por Elsevier España, S.L.U. All rights reserved.)

Published
2021
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