1. Association of random glucose to albumin ratio with post-contrast acute kidney injury and clinical outcomes in patients with ST-elevation myocardial infarction
- Author
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Ping Lai, Xiaoyan Gu, Xuhui Lin, Yu He, Yining Dai, Chongyang Duan, Yuanhui Liu, and Wenfei He
- Subjects
random glucose ,albumin ,post-contrast acute kidney injury ,ST-segment elevation myocardial infarction ,percutaneous coronary intervention ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
PurposeBoth glucose and albumin are associated with chronic inflammation, which plays a vital role in post-contrast acute kidney injury (PC-AKI). To explore the relationship between random glucose to albumin ratio (RAR) and the incidence of PC-AKI after percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI).Patients and methodsSTEMI patients who underwent PCI were consecutively enrolled from January, 01, 2010 to February, 28, 2020. All patients were categorized into T1, T2, and T3 groups, respectively, based on RAR value (RAR < 3.377; 3.377 ≤ RAR ≤ 4.579; RAR > 4.579). The primary outcome was the incidence of PC-AKI, and the incidence of major adverse clinical events (MACE) was the second endpoint. The association between RAR and PC-AKI was assessed by multivariable logistic regression analysis.ResultsA total of 2,924 patients with STEMI undergoing PCI were finally included. The incidence of PC-AKI increased with the increasing tertile of RAR (3.2% vs 4.8% vs 10.6%, P
- Published
- 2024
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