380 results on '"Pineton de Chambrun, Marc"'
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2. Thrombolysis before venoarterial ECMO for high-risk pulmonary embolism: a retrospective cohort study
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Levy, David, Saura, Ouriel, Passarelli, Maria Teresa, Lucenteforte, Manuela, Lebreton, Guillaume, Bougle, Adrien, Monsel, Antoine, Ortuno, Sofia, Benitha, Yoël, Hammoudi, Nadjib, Assouline, Benjamin, Petit, Matthieu, Gautier, Melchior, Le Fevre, Lucie, Pineton de Chambrun, Marc, Juvin, Charles, Chommeloux, Juliette, Luyt, Charles-Edouard, Hékimian, Guillaume, Leprince, Pascal, Combes, Alain, and Schmidt, Matthieu
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- 2024
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3. Antiphospholipid Patients Admitted in the Intensive Care Unit: What Must The Rheumatologist Know?
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Moyon, Quentin, Mathian, Alexis, Papo, Matthias, Combes, Alain, Amoura, Zahir, and Pineton de Chambrun, Marc
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- 2024
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4. Mechanical ventilation settings during weaning from venovenous extracorporeal membrane oxygenation
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Passarelli, Maria Teresa, Petit, Matthieu, Garberi, Roberta, Lebreton, Guillaume, Luyt, Charles Edouard, Pineton De Chambrun, Marc, Chommeloux, Juliette, Hékimian, Guillaume, Rezoagli, Emanuele, Foti, Giuseppe, Combes, Alain, Giani, Marco, and Schmidt, Matthieu
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- 2024
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5. Recurrent ventilator-associated pneumonia in severe Covid-19 ARDS patients requiring ECMO support
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Collado-Lledó, Elena, Moyon, Quentin, Chommeloux, Juliette, Pineton de Chambrun, Marc, Hékimian, Guillaume, Saura, Ouriel, Lévy, David, Schmidt, Matthieu, Combes, Alain, Luyt, Charles-Edouard, and Le Fevre, Lucie
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- 2024
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6. Authors reply in response to a letter on: “Diagnostic yield, safety and therapeutic consequences of myocardial biopsy in clinically suspected fulminant myocarditis unweanable from mechanical circulatory support”
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Pineton de Chambrun, Marc, Marquet, Yann, Kerneis, Mathieu, Schmidt, Matthieu, Luyt, Charles-Edouard, Combes, Alain, and Hekimian, Guillaume
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- 2024
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7. Venoarterial extracorporeal membrane oxygenation in immunocompromised patients with cardiogenic shock: a cohort study and propensity-weighted analysis
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Moyon, Quentin, Triboulet, Félicien, Reuter, Jean, Lebreton, Guillaume, Dorget, Amandine, Para, Marylou, Chommeloux, Juliette, Stern, Jules, Pineton de Chambrun, Marc, Hékimian, Guillaume, Luyt, Charles-Edouard, Combes, Alain, Sonneville, Romain, and Schmidt, Matthieu
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- 2024
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8. Bleeding complications, coagulation disorders, and their management in acute myocardial infarction-related cardiogenic shock rescued by veno-arterial ECMO: A retrospective cohort study
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Masi, Paul, Gendreau, Ségolène, Moyon, Quentin, Leguyader, Maxence, Lebreton, Guillaume, Ropers, Jacques, Dangers, Laurence, Sitruk, Samuel, Bréchot, Nicolas, Pineton de Chambrun, Marc, Chommeloux, Juliette, Schmidt, Matthieu, Luyt, Charles Edouard, Leprince, Pascal, Combes, Alain, Frere, Corinne, and Hékimian, Guillaume
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- 2024
- Full Text
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9. Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection
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Abel, Laurent, Aiuti, Alessandro, Al-Muhsen, Saleh, Al-Mulla, Fahd, Amara, Ali, Anderson, Mark S., Andreakos, Evangelos, Arias, Andrés A., Arkin, Lisa M., Feldman, Hagit Baris, Bastard, Paul, Belot, Alexandre, Biggs, Catherine M., Bogunovic, Dusan, Bolze, Alexandre, Bondarenko, Anastasiia, Borghesi, Alessandro, Bousfiha, Ahmed A., Brodin, Petter, Bryceson, Yenan, Butte, Manish J., Casanova, Jean-Laurent, Casari, Giorgio, Christodoulou, John, Cobat, Aurélie, Colobran, Roger, Condino-Neto, Antonio, Constantinescu, Stefan N., Cooper, Megan A., Dalgard, Clifton L., Desai, Murkesh, Drolet, Beth A., Duval, Xavier, El Baghdadi, Jamila, Eloy, Philippine, Espinosa-Padilla, Sara, Fellay, Jacques, Flores, Carlos, Franco, José Luis, Froidure, Antoine, Gorochov, Guy, Gregersen, Peter K., Grimbacher, Bodo, Haerynck, Filomeen, Hagin, David, Halwani, Rabih, Hammarström, Lennart, Heath, James R., Hsieh, Elena W.Y., Husebye, Eystein, Imai, Kohsuke, Itan, Yuval, Jouanguy, Emmanuelle, Kaja, Elżbieta, Karamitros, Timokratis, Kisand, Kai, Ku, Cheng-Lung, Lau, Yu-Lung, Ling, Yun, Lucas, Carrie L., Maniatis, Tom, Mansouri, Davood, Maródi, László, Mentré, France, Meyts, Isabelle, Milner, Joshua D., Mironska, Kristina, Mogensen, Trine H., Morio, Tomohiro, Ng, Lisa F.P., Notarangelo, Luigi D., Novelli, Antonio, Novelli, Giuseppe, O'Farrelly, Cliona, Okada, Satoshi, Okamoto, Keisuke, Ozcelik, Tayfun, Pan-Hammarström, Qiang, Pape, Jean W., Perez de Diego, Rebeca, Perez-Tur, Jordi, Perlin, David S., Pesole, Graziano, Planas, Anna M., Prando, Carolina, Pujol, Aurora, Puel, Anne, Quintana-Murci, Lluis, Ramaswamy, Sathishkumar, Renia, Laurent, Resnick, Igor, Rodríguez-Gallego, Carlos, Sancho-Shimizu, Vanessa, Sediva, Anna, Seppänen, Mikko R.J., Shahrooei, Mohammad, Shcherbina, Anna, Slaby, Ondrej, Snow, Andrew L., Soler-Palacín, Pere, Soumelis, Vassili, Spaan, András N., Tancevski, Ivan, Tangye, Stuart G., Tayoun, Ahmad Abou, Temel, Şehime Gülsün, Thorball, Christian, Tiberghien, Pierre, Trouillet-Assant, Sophie, Turvey, Stuart E., Uddin, K. M. Furkan, Uddin, Mohammed J., van de Beek, Diederik, Vinh, Donald C., von Bernuth, Horst, Wauters, Joost, Zatz, Mayana, Zawadzki, Pawel, Zhang, Qian, Zhang, Shen-Ying, Bureau, Serge, Vacher, Yannick, Gysembergh-Houal, Anne, Demerville, Lauren, Benleulmi-Chaachoua, Abla, Abad, Sebastien, Abassi, Radhiya, Abdellaoui, Abdelrafie, Abdelmalek, Abdelkrim, Abdoul, Hendy, Abergel, Helene, Abeud, Fariza, Abgrall, Sophie, Abisror, Noemie, Adechian, Marylise, Aderdour, Nordine, Admane, Hakeem Farid, Adnet, Frederic, Afritt, Sara, Agostini, Helene, Aguilar, Claire, Agut, Sophie, Aiello, Tommaso Francesco, Kaci, Marc Ait, Oufella, Hafid Ait, Ajeenthiravasan, Gokula, Alauzy, Virginie, Alby-Laurent, Fanny, Allard, Lucie, Alyanakian, Marie-Alexandra, Borrero, Blanca Amador, Amam, Sabrina, Amrouche, Lucile, Andronikof, Marc, Anglicheau, Dany, Anguel, Nadia, Annane, Djillali, Aounzou, Mohammed, Aparicio, Caroline, Aratus, Gladys, Arlet, Jean-Benoit, Arzoine, Jeremy, Aslangul, Elisabeth, Assefi, Mona, Aubry, Adeline, Audiffred, Laetitia, Audureau, Etienne, Auger, Christelle Nathalie, Auregan, Jean-Charles, Awotar, Celine, Milla, Sonia Ayllon, Azan, Delphine, Azemar, Laurene, Azzouguen, Billal, Elrufaai, Marwa Bachir, Badsi, Aïda, Bakouboula, Prissile, Balcerowiak, Coline, Balde, Fanta, Baldivia, Elodie, Bangamingo, Eliane-Flore, Baptiste, Amandine, Baran-Marszak, Fanny, Barau, Caroline, Barget, Nathalie, Baronnet, Flore, Barthelemy, Romain, Baudel, Jean-Luc, Baudry, Camille, Baudry, Elodie, Beaugerie, Laurent, Belamri, Adel, Belaube, Nicolas, Belilita, Rhida, Bellassen, Pierre, Belmokhtar, Rawan, Beltran, Isabel, Benainous, Ruben, Benallaoua, Mourad, Benamouzig, Robert, Benbara, Amélie, Benhida, Jaouad, Benkhelouf, Anis, Benlagha, Jihene, Benmostafa, Chahinez, Benothmane, Skander, Bentifraouine, Miassa, Berard, Laurence, Bernier, Quentin, Berti, Enora, Bertier, Astrid, Berton, Laure, Bessis, Simon, Beurton, Alexandra, Bianco, Celine, Bianquis, Clara, Bidar, Frank, Blanche, Philippe, Blayau, Clarisse, Bleibtreu, Alexandre, Blin, Emmanuelle, Bloch-Queyrat, Coralie, Boissier, Marie-Christophe, Bollens, Diane, Bolzoni, Marion, Bompard, Rudy pierre, Bonnet, Nicolas, Bonnouvrier, Justine, Botha, Shirmonecrystal, Boucenna, Wissam, Bouchama, Fatiha, Bouchaud, Olivier, Bouchghoul, Hanane, Boudjebla, Taoueslylia, Boudjema, Noel, Bouffard, Catherine, Bougle, Adrien, Bouguerra, Meriem, Bouras, Leila, Bourcier, Agnes, Durand, Anne Bourgarit, Bourrier, Anne, Bouscarat, Fabrice, Bouvry, Diane, Bouziri, Nesrine, Bouzrara, Ons, Bribier, Sarah, Brugier, Delphine, Brunel, Melanie, Bui, Eida, Buisson, Anne, Bukreyeva, Iryna, Bureau, Côme, Cadranel, Jacques, Cailhol, Johann, Calin, Ruxandra, Vega, Clara Campos, Canavaggio, Pauline, Cancella, Marta, Cantin, Delphine, Cao, Albert, Carbillon, Lionel, Carlier, Nicolas, Cassard, Clementine, Castor, Guylaine, Cauchy, Marion, Cha, Olivier, Chaigne, Benjamin, Challal, Salima, Champion, Karine, Chariot, Patrick, Chas, Julie, Chauveau, Simon, Chauvin, Anthony, Chauvin, Clement, Chavarot, Nathalie, Chebbout, Kamélia, Cherai, Mustapha, Cherubini, Ilaria, Chevalier, Amelie, Chiarabini, Thibault, Chinet, Thierry, Chocron, Richard, Choinier, Pascaline, Chommeloux, Juliette, Choquet, Christophe, Choupeaux, Laure, Chousterman, Benjamin, Ciocan, Dragosmarius, Clarke, Ada, Clavere, Gaëlle, Clavier, Florian, Clement, Karine, Clerc, Sebastien, Cohen, Yves, Cohen, Fleur, Cohen, Adrien, Coilly, Audrey, Colboc, Hester, Colin, Pauline, Collet, Magalie, Comarmond, Chloé, Combacon, Emeline, Combes, Alain, Comparon, Celine, Constantin, Jean-Michel, Cordel, Hugues, Cordier, Anne-Gael, Costantini, Adrien, Chalumeau, Nathalie Costedoat, Couffignal, Camille, Coupeau, Doriane, Creange, Alain, Lamarre, Yannie Cuvillier, Da Silveira, Charlène, Guibal El Kayani, Sandrine Dautheville, De Castro, Nathalie, De Rycke, Yann, Del Pozo, Lucie, Delannoy, Quentin, Delay, Mathieu, Deleris, Robin, Delforge, Juliette, Delphine, Laëtitia, Demare, Noemie, Demeret, Sophie, Demoule, Alexandre, Deniau, Aurore, Depret, François, Derolez, Sophie, Derradji, Ouda, Derridj, Nawal, Descamps, Vincent, Deschamps, Lydia, Desconclois, Celine, Desnos, Cyrielle, Desongins, Karine, Dhote, Robin, Diallo, Benjamin, Didier, Morgane, Diemer, Myriam, Diez, Stephane, Djadi-Prat, Juliette, Djamouri Monnory, Fatima-Zohra, Djebara, Siham, Djebra, Naoual, Djietcheu, Minette, Djillali, Hadjer, Djouadi, Nouara, Donneger, Severine, Santos, Catarina Dos, Dournon, Nathalie, Dres, Martin, Droctove, Laura, Drogrey, Marie, Dropy, Margot, Drouet, Elodie, Dubosq, Valérie, Dubreucq, Evelyne, Dubus, Estelle, Duchemann, Boris, Duchenoy, Thibault, Dudoignon, Emmanuel, Dufau, Romain, Dumas, Florence, Duran, Clara, Duron, Emmanuelle, Durrbach, Antoine, Duvivier, Claudine, Ebstein, Nathan, El Khalifa, Jihane, Elabbadi, Alexandre, Elie, Caroline, Ernotte, Gabriel, Esling, Anne, Etienne, Martin, Eyer, Xavier, Fartoukh, Muriel Sarah, Fayali, Takoua, Fermaut, Marion, Fiorentino, Arianna, Fliss, Souha, Fournier, Marie-Céline, Fournier, Benjamin, Francois, Hélène, Freynet, Olivia, Frigout, Yvann, Fromont, Isaure, Fuentes, Axelle, Furet, Thomas, Galand, Joris, Garnier, Marc, Gaubert, Agnes, Gaudry, Stéphane, Gaugain, Samuel, Gauthier, Damien, Gautier, Maxime, Georgin-Lavialle, Sophie, Geromin, Daniela, Ghalayini, Mohamed, Ghaleh, Bijan, Ghezal, Myriam, Gibelin, Aude, Gimeno, Linda, Girard, Benoit, Leprieur, Bénédicte Giroux, Gomes, Doryan, Gomes-Pires, Elisabete, Gouge, Anne, Gouja, Amel, Goulet, Helene, Goupil, Sylvain, De Bouille, Jeanne Goupil, Gras, Julien, Greffe, Segolene, Grimaldi, Lamiae, Guedeney, Paul, Guidet, Bertrand, Guillo, Matthias, Gulczynski, Mariechristelle, Hadjam, Tassadit, Haguenauer, Didier, Hammal, Soumeya, Hammoudi, Nadjib, Hanon, Olivier, Harrois, Anarole, Hausfater, Pierre, Hautem, Coraline, Hekimian, Guillaume, Heming, Nicholas, Hermine, Olivier, Ho, Sylvie, Houllier, Marie, Huot, Benjamin, Huscenot, Tessa, Saied, Wafa Ibn, Ikherbane, Ghilas, Imarazene, Meriem, Ingiliz, Patrick, Iratni, Lina, Jaureguiberry, Stephane, Jean-Marc, Jean-Francois, Jeyarajasingham, Deleena, Jouany, Pauline, Jouis, Veronique, Jourdaine, Clement, Kafif, Ouifiya, Kallala, Rim, Katsahian, Sandrine, Kelesyan, Lilit, Keo, Vixra, Ketz, Flora, Khamis, Warda, Khelili, Enfel, Khellaf, Mehdi, Kotokpo Youkou, Christy Gaëlla, Kounis, Ilias, Kpalma, Gaelle, Krause, Jessica, Labbe, Vincent, Lacombe, Karine, Lacorte, Jean-Marc, Lafont, Anne Gaelle, Lafont, Emmanuel, Lagha, Lynda, Lamhaut, Lionel, Lancelot, Aymeric, Landman, Cecilia, Lanternier, Fanny, Larcheveque, Cecile, Combe, Caroline Lascoux, Lassel, Ludovic, Laverdant, Benjamin, Lavergne, Christophe, Lavillegrand, Jean-Rémi, Lazureanu, Pompilia, Le Guennec, Loïc, Leberre, Lamia, Leblanc, Claire, Leboyer, Marion, Lecomte, Francois, Lecorre, Marine, Leenhardt, Romain, Lefebvre, Marylou, Lefebvre, Bénédicte, Legendre, Paul, Leger, Anne, Legros, Laurence, Legrosse, Justyna, Lehuunghia, Sébastien, Lemarec, Julien, Leporrier-Ext, Jeremie, Lesein, Manon, Lesur, Hubert, Levy, Vincent, Levy, Albert, Lopes, Edwige, Lopes, Amanda, Lopez, Vanessa, Lopinto, Julien, Lortholary, Olivier, Louadah, Badr, Loze, Bénédicte, Lucas, Marie-Laure, Lucasamichi, Axelle, Luong, Liem Binh, Magazimama-Ext, Arouna, Maingret, David, Mameri, Lakhdar, Manivet, Philippe, Mansouri, Cylia, Marcault, Estelle, Marey, Jonathan, Marin, Nathalie, Marois, Clémence, Martin, Olivier, Martineau, Lou, Martinez-Lopez, Cannelle, Martyniuck, Pierre, De Farcy, Pauline Mary, Marzouk, Nessrine, Masmoudi, Rafik, Mebazaa, Alexandre, Mechai, Frédéric, Mecozzi, Fabio, Mediouni, Chamseddine, Megarbane, Bruno, Meghadecha, Mohamed, Mejean, Élodie, Mekinian, Arsene, Abdelhadi, Nour Mekki, Mekni, Rania, Meliti, Thinhinan Sabrina, Lima, Breno Melo, Meng, Paris, Merbah, Soraya, Messani, Fadhila, Messaoudi, Yasmine, Mewasing, Baboo-Irwinsingh, Meziane, Lydia, Michelot-Burger, Carole, Mignot, Françoise, Minka, Fadi Hillary, Miyara, Makoto, Moine, Pierre, Molina, Jean-Michel, Montegnies-Boulet, Anaïs, Monti, Alexandra, Montlahuc, Claire, Montout, Anne-Lise, Moores, Alexandre, Morbieu, Caroline, Mortelette, Helene, Mouly, Stéphane, Muzaffar, Rosita, Nacerddine, Cherifa Iness, Nadal, Marine, Nadif, Hajer, Nassarmadji, Kladoum, Natella, Pierre, Ndingamondze, Sandrine, Neraal, Stefan, Nguyen, Caroline, N'Guyen, Bao, Larmurier, Isabelle Nion, Nlomenyengue, Luc, Noel, Nicolas, Nunes, Hilario, Omar, Edris, Ouazene, Zineb, Ouedraogo, Elise, Ouelaa, Wassila, Oukhedouma, Anissa, Amara, Yasmina Ould, Oya, Herve, Oziel, Johanna, Padilla, Thomas, Paillaud, Elena, Paiva, Solenne, Parfait, Beatrice, Parize, Perrine, Parizot, Christophe, Parrot, Antoine, Pavot, Arthur, Peaudecerf, Laetitia, Pene, Frédéric, Pepin, Marion, Pernet, Julie, Pernin, Claire, Petit, Mylène, Peyrony, Olivier, Pietri, Marie-Pierre, Pietri, Olivia, De Chambrun, Marc Pineton, Pinson, Michelle, Pintado, Claire, Piquard, Valentine, Pires, Christine, Planquette, Benjamin, Poirier, Sandrine, Pomel, Anne-Laure, Pons, Stéphanie, Ponscarme, Diane, Pourcelot, Annegaelle, Pourcher, Valérie, Pouvaret, Anne, Prever, Florian, Previlon, Miresta, Prevost, Margot, Provoost, Marie-Julie, Quemeneur, Cyril, Rafat, Cédric, Rami, Agathe, Ranque, Brigitte, Raphael, Maurice, Raphalen, Jean Herle, Rastoin, Anna, Raux, Mathieu, Rebai, Amani, Reby, Michael, Regent, Alexis, Regrag, Asma, Resche-Rigon, Matthieu, Ressaire, Quentin, Richard, Christian, Richard, Mariecaroline, Robert, Maxence, Rohaut, Benjamin, Rolland-Debord, Camille, Ropers, Jacques, Roque-Afonso, Anne-Marie, Rosso, Charlotte, Rousseaux, Mélanie, Rousseaux, Nabila, Roux, Swasti, Roux, Lorène, Rouzaud, Claire, Rozes, Antoine, Rubenstein, Emma, Sabate, Jean-Marc, Sabet, Sheila, Sacleux, Sophie-Caroline, Kermanach, Nathalie Saidenberg, Saliba, Faouzi, Salmon, Dominique, Savale, Laurent, Savary, Guillaume, Sberro, Rebecca, Scemla, Anne, Schlemmer, Frederic, Schwartz, Mathieu, Sedfi, Saïd, Sefir-Kribel, Samia, Seksik, Philippe, Sellier, Pierre, Selves, Agathe, Sembach, Nicole, Semerano, Luca, Senat, Marie-Victoire, Sene, Damien, Serris, Alexandra, Sese, Lucile, Sghiouar, Naima, Sigaux, Johanna, Siguier, Martin, Silvain, Johanne, Simon, Noémie, Simon, Tabassome, Skandri, Lina Innes, Slimani, Miassa, Snauwaert, Aurélie, Sokol, Harry, Soliman, Heithem, Soltani, Nisrine, Soyer, Benjamin, Steg, Gabriel, Suarez, Lydia, Szwebel, Tali-Anne, Taffame, Kossi, Tandjaoui-Lambiotte, Yacine, Tantet, Claire, Tateo, Mariagrazia, Theodose, Igor, Thiebaud, Pierre clement, Thomas, Caroline, Tiercelet, Kelly, Tisserand, Julie, Tomczak, Carole, Torelino, Krystel, Touam-Ext, Fatima, Toumi, Lilia, Toury, Gustave, Toy-Miou, Mireille, Dinh Thanh Lien, Olivia Tran, Trandinh, Alexy, Treluyer, Jean-Marc, Trinque, Baptiste, Truchot, Jennifer, Tubach, Florence, Tubiana, Sarah, Tunesi, Simone, Turpin, Matthieu, Turpin, Agathe, Urbina, Tomas, Narvaez, Rafael Usubillaga, Uzunhan, Yurdagul, Vaittinadaayar, Prabakar, Valent, Arnaud, Valentian, Maelle, Valin, Nadia, Vallet, Hélène, Vaz, Marina, Vazquezibarra, Miguel-Alejandro, Vedie, Benoit, Velly, Laetitia, Verstuyft, Celine, Viallette, Cedric, Vicaut, Eric, Vignes, Dorothee, Vimpere, Damien, Virlouvet, Myriam, Voiriot, Guillaume, Voisot, Lena, Weiss, Emmanuel, Weiss, Nicolas, Winchenne, Anaïs, Yordanov, Youri, Zafrani, Lara, Zaidan, Mohamad, Zaidi, Wissem, Zak, Cathia, Zarhrate-Ghoul, Aida, Zatout, Ouassila, Zeino, Suzanne, Zeitouni, Michel, Zemirli, Naïma, Zerah, Lorene, Zia, Ounsa, Ziol, Marianne, Zolario, Oceane, Zuber, Julien, Andrejak, Claire, Angoulvant, François, Bachelet, Delphine, Bartoli, Marie, Basmaci, Romain, Behillil, Sylvie, Beluze, Marine, Benkerrou, Dehbia, Bhavsar, Krishna, Bouadma, Lila, Bouchez, Sabelline, Bouscambert, Maude, Cervantes-Gonzalez, Minerva, Chair, Anissa, Chirouze, Catherine, Coelho, Alexandra, Couffin-Cadiergues, Sandrine, d’Ortenzio, Eric, Debray, Marie-Pierre, Deconinck, Laurene, Deplanque, Dominique, Descamps, Diane, Desvallée, Mathilde, Diallo, Alpha, Diouf, Alphonsine, Dorival, Céline, Dubos, François, Elharrar, Brigitte, Enouf, Vincent, Esperou, Hélène, Esposito-Farese, Marina, Etienne, Manuel, Devouge, Eglantine Ferrand, Gault, Nathalie, Gaymard, Alexandre, Ghosn, Jade, Gigante, Tristan, Gilg, Morgane, Guedj, Jérémie, Hoctin, Alexandre, Hoffmann, Isabelle, Houas, Ikram, Hulot, Jean-Sébastien, Jaafoura, Salma, Kaguelidou, Florentia, Kali, Sabrina, Khalil, Antoine, Khan, Coralie, Laouénan, Cédric, Laribi, Samira, Le, Minh, Le Hingrat, Quentin, Le Mestre, Soizic, Le Nagard, Hervé, Lescure, François-Xavier, Letrou, Sophie, Levy, Yves, Lina, Bruno, Lingas, Guillaume, Lucet, Jean-Christophe, Malvy, Denis, Mambert, Marina, Meziane, Amina, Mouquet, Hugo, Mullaert, Jimmy, Neant, Nadège, Nguyen, Duc, Noret, Marion, Nseir, Saad, Papadopoulos, Aurélie, Paul, Christelle, Peiffer-Smadja, Nathan, Perpoint, Thomas, Petrov-Sanchez, Ventzislava, Peytavin, Gilles, Pham, Huong, Picone, Olivier, Puéchal, Oriane, Rabaud, Christian, Rosa-Calatrava, Manuel, Rossignol, Bénédicte, Rossignol, Patrick, Roy, Carine, Schneider, Marion, Su, Richa, Tardivon, Coralie, Tellier, Marie-Capucine, Téoulé, François, Terrier, Olivier, Timsit, Jean-François, Tual, Christelle, Van Der Werf, Sylvie, Vanel, Noémie, Veislinger, Aurélie, Visseaux, Benoit, Wiedemann, Aurélie, Yazdanpanah, Yazdan, Alavoine, Loubna, Burdet, Charles, Charpentier, Charlotte, Dechanet, Aline, Ecobichon, Jean-Luc, Frezouls, Wahiba, Houhou, Nadhira, Lehacaut, Jonathan, Manchon, Pauline, Nouroudine, Mariama, Quintin, Caroline, Thy, Michael, van der Werf, Sylvie, Vignali, Valérie, Chahine, Abir, Waucquier, Nawal, Migaud, Maria-Claire, Djossou, Félix, Mergeay-Fabre, Mayka, Lucarelli, Aude, Demar, Magalie, Bruneau, Léa, Gérardin, Patrick, Maillot, Adrien, Payet, Christine, Laviolle, Bruno, Laine, Fabrice, Paris, Christophe, Desille-Dugast, Mireille, Fouchard, Julie, Pistone, Thierry, Perreau, Pauline, Gissot, Valérie, Goas, Carole L.E., Montagne, Samatha, Richard, Lucie, Bouiller, Kévin, Desmarets, Maxime, Meunier, Alexandre, Bourgeon, Marilou, Lefévre, Benjamin, Jeulin, Hélène, Legrand, Karine, Lomazzi, Sandra, Tardy, Bernard, Gagneux-Brunon, Amandine, Bertholon, Frédérique, Botelho-Nevers, Elisabeth, Kouakam, Christelle, Nicolas, Leturque, Roufai, Layidé, Amat, Karine, Espérou, Hélène, Hendou, Samia, Foti, Giuseppe, Citerio, Giuseppe, Contro, Ernesto, Pesci, Alberto, Valsecchi, Maria Grazia, Cazzaniga, Marina, Bellani, Giacomo, Abad, Jorge, Accordino, Giulia, Angelini, Micol, Aguilera-Albesa, Sergio, Aguiló-Cucurull, Aina, Özkan, Esra Akyüz, Darazam, Ilad Alavi, Roblero Albisures, Jonathan Antonio, Aldave, Juan C., Ramos, Miquel Alfonso, Khan, Taj Ali, Aliberti, Anna, Nadji, Seyed Alireza, Alkan, Gulsum, AlKhater, Suzan A., Allardet-Servent, Jerome, Allende, Luis M., Alonso-Arias, Rebeca, Alshahrani, Mohammed S., Alsina, Laia, Amoura, Zahir, Antolí, Arnau, Arrestier, Romain, Aubart, Mélodie, Auguet, Teresa, Avramenko, Iryna, Aytekin, Gökhan, Azot, Axelle, Bahram, Seiamak, Bajolle, Fanny, Baldanti, Fausto, Baldolli, Aurélie, Ballester, Maite, Barrou, Benoit, Barzaghi, Federica, Basso, Sabrina, Bayhan, Gulsum Iclal, Bezrodnik, Liliana, Bilbao, Agurtzane, Blanchard-Rohner, Geraldine, Blanco, Ignacio, Blandinières, Adeline, Blázquez-Gamero, Daniel, Bloomfield, Marketa, Bolivar-Prados, Mireia, Borie, Raphael, Botdhlo-Nevers, Elisabeth, Bousquet, Aurore, Boutolleau, David, Bouvattier, Claire, Boyarchuk, Oksana, Bravais, Juliette, Briones, M. Luisa, Brunner, Marie-Eve, Bruno, Raffaele, Bueno, Maria Rita P., Bukhari, Huda, Bustamante, Jacinta, Cáceres Agra, Juan José, Capra, Ruggero, Carapito, Raphael, Carrabba, Maria, Casasnovas, Carlos, Caseris, Marion, Cassaniti, Irene, Castelle, Martin, Castelli, Francesco, Castillo de Vera, Martín, Castro, Mateus V., Catherinot, Emilie, Celik, Jale Bengi, Ceschi, Alessandro, Chalumeau, Martin, Charbit, Bruno, Boulanger, Cécile, Clavé, Père, Clotet, Bonaventura, Codina, Anna, Comarmond, Cloé, Comoli, Patrizia, Corsico, Angelo G., Coşkuner, Taner, Cvetkovski, Aleksandar, Cyrus, Cyril, Dalmau, David, Danion, François, Darley, David Ross, Das, Vincent, Dauby, Nicolas, Dauger, Stéphane, De Munte, Paul, de Pontual, Loic, Dehban, Amin, Delplancq, Geoffroy, Desguerre, Isabelle, Di Sabatino, Antonio, Diehl, Jean-Luc, Dobbelaere, Stephanie, Domínguez-Garrido, Elena, Dubost, Clément, Ekwall, Olov, Bozdemir, Şefika Elmas, Elnagdy, Marwa H., Emiroglu, Melike, Endo, Akifumi, Erdeniz, Emine Hafize, Aytekin, Selma Erol, Etxart Lasa, Maria Pilar, Euvrard, Romain, Fabio, Giovanna, Faivre, Laurence, Falck, Antonin, Fartoukh, Muriel, Faure, Morgane, Arquero, Miguel Fernandez, Ferrer, Ricard, Ferreres, Jose, Francois, Bruno, Fumadó, Victoria, Fung, Kitty S.C., Fusco, Francesca, Gagro, Alenka, Solis, Blanca Garcia, Garçon, Pierre, Gaussem, Pascale, Gayretli, Zeynep, Gil-Herrera, Juana, Gilardin, Laurent, Gatineau, Audrey Giraud, Girona-Alarcón, Mònica, Cifuentes Godínez, Karen Alejandra, Goffard, Jean-Christophe, Gonzales, Nacho, Gonzalez-Granado, Luis I., González-Montelongo, Rafaela, Guerder, Antoine, Gülhan, Belgin, Gumucio, Victor Daniel, Hanitsch, Leif Gunnar, Gunst, Jan, Gut, Marta, Hadjadj, Jérôme, Hancerli, Selda, Hariyan, Tetyana, Hatipoglu, Nevin, Heppekcan, Deniz, Hernandez-Brito, Elisa, Ho, Po-ki, Holanda-Peña, María Soledad, Horcajada, Juan P., Hraiech, Sami, Humbert, Linda, Hung, Ivan F.N., Iglesias, Alejandro D., Íñigo-Campos, Antonio, Jamme, Matthieu, Arranz, María Jesús, Jimeno, Marie-Thérèse, Jordan, Iolanda, Kanık-Yüksek, Saliha, Kara, Yalcin, Karahan, Aydın, Karbuz, Adem, Yasar, Kadriye Kart, Kasapcopur, Ozgur, Kashimada, Kenichi, Keles, Sevgi, Demirkol, Yasemin Kendir, Kido, Yasutoshi, Kizil, Can, Kılıç, Ahmet Osman, Klocperk, Adam, Koutsoukou, Antonia, Król, Zbigniew J., Ksouri, Hatem, Kuentz, Paul, Kwan, Arthur M.C., Kwan, Yat Wah M., Kwok, Janette S.Y., Lagier, Jean-Christophe, Lam, David S.Y., Lampropoulou, Vicky, Le Bourgeois, Fleur, Leo, Yee-Sin, Lopez, Rafael Leon, Leung, Daniel, Levin, Michael, Levy, Michael, Lévy, Romain, Li, Zhi, Lilleri, Daniele, Adrian Bolanos Lima, Edson Jose, Linglart, Agnes, López-Collazo, Eduardo, Lorenzo-Salazar, José M., Louapre, Céline, Lubetzki, Catherine, Lung, Kwok-Cheung, Luyt, Charles-Edouard, Lye, David C., Magnone, Cinthia, Marchioni, Enrico, Marioli, Carola, Marjani, Majid, Marques, Laura, Pereira, Jesus Marquez, Martín-Nalda, Andrea, Pueyo, David Martínez, Martinez-Picado, Javier, Marzana, Iciar, Mata-Martínez, Carmen, Mathian, Alexis, Matos, Larissa R.B., Matthews, Gail V., Mayaux, Julien, McLaughlin-Garcia, Raquel, Meersseman, Philippe, Mège, Jean-Louis, Mekontso-Dessap, Armand, Melki, Isabelle, Meloni, Federica, Meritet, Jean-François, Merlani, Paolo, Akcan, Özge Metin, Mezidi, Mehdi, Migeotte, Isabelle, Millereux, Maude, Million, Matthieu, Mirault, Tristan, Mircher, Clotilde, Mirsaeidi, Mehdi, Mizoguchi, Yoko, Modi, Bhavi P., Mojoli, Francesco, Moncomble, Elsa, Melián, Abián Montesdeoca, Martinez, Antonio Morales, Morandeira, Francisco, Morange, Pierre-Emmanuel, Mordacq, Clémence, Morelle, Guillaume, Mouly, Stéphane J., Muñoz-Barrera, Adrián, Nafati, Cyril, Nagashima, Shintaro, Nakagama, Yu, Neven, Bénédicte, Neves, João Farela, Ng, Yuk-Yung, Hubert Nielly, Medina, Yeray Novoa, Cuadros, Esmeralda Nuñez, Karabela, Semsi Nur, Ocejo-Vinyals, J. Gonzalo, Oualha, Mehdi, Ouedrani, Amani, Özçelik, Tayfun, Ozkaya-Parlakay, Aslinur, Pagani, Michele, Papadaki, Maria, Parola, Philippe, Pascreau, Tiffany, Paul, Stéphane, Paz-Artal, Estela, Pedraza, Sigifredo, González Pellecer, Nancy Carolina, Pellegrini, Silvia, Pérez de Diego, Rebeca, Pérez-Fernández, Xosé Luis, Philippe, Aurélien, Philippot, Quentin, Picod, Adrien, Pineton de Chambrun, Marc, Piralla, Antonio, Planas-Serra, Laura, Ploin, Dominique, Poissy, Julien, Poncelet, Géraldine, Poulakou, Garyphallia, Pouletty, Marie S., Pourshahnazari, Persia, Qiu-Chen, Jia Li, Quentric, Paul, Rambaud, Thomas, Raoult, Didier, Raoult, Violette, Rebillat, Anne-Sophie, Redin, Claire, Resmini, Léa, Ricart, Pilar, Richard, Jean-Christophe, Rigo-Bonnin, Raúl, Rivet, Nadia, Rivière, Jacques G., Rocamora-Blanch, Gemma, Rodero, Mathieu P., Rodrigo, Carlos, Rodriguez, Luis Antonio, Rodriguez-Gallego, Carlos, Rodriguez-Palmero, Agustí, Romero, Carolina Soledad, Rothenbuhler, Anya, Roux, Damien, Rovina, Nikoletta, Rozenberg, Flore, Ruch, Yvon, Ruiz, Montse, Ruiz del Prado, Maria Yolanda, Ruiz-Rodriguez, Juan Carlos, Sabater-Riera, Joan, Saks, Kai, Salagianni, Maria, Sanchez, Oliver, Sánchez-Montalvá, Adrián, Sánchez-Ramón, Silvia, Schidlowski, Laire, Schluter, Agatha, Schmidt, Julien, Schmidt, Matthieu, Schuetz, Catharina, Schweitzer, Cyril E., Scolari, Francesco, Seijo, Luis, Seminario, Analia Gisela, Seng, Piseth, Senoglu, Sevtap, Seppänen, Mikko, Llovich, Alex Serra, Siguret, Virginie, Siouti, Eleni, Smadja, David M., Smith, Nikaia, Sobh, Ali, Solanich, Xavier, Solé-Violán, Jordi, Soler, Catherine, Sözeri, Betül, Stella, Giulia Maria, Stepanovskiy, Yuriy, Stoclin, Annabelle, Taccone, Fabio, Taupin, Jean-Luc, Tavernier, Simon J., Tello, Loreto Vidaur, Terrier, Benjamin, Thiery, Guillaume, Thorn, Karolina, Thumerelle, Caroline, Tipu, Imran, Tolstrup, Martin, Tomasoni, Gabriele, Toubiana, Julie, Alvarez, Josep Trenado, Triantafyllia, Vasiliki, Troya, Jesús, Tsang, Owen T.Y., Tserel, Liina, Tso, Eugene Y.K., Tucci, Alessandra, Tüter Öz, Şadiye Kübra, Ursini, Matilde Valeria, Utsumi, Takanori, Vabres, Pierre, Valencia-Ramos, Juan, Van Den Rym, Ana Maria, Vandernoot, Isabelle, Velez-Santamaria, Valentina, Zuniga Veliz, Silvia Patricia, Vidigal, Mateus C., Viel, Sébastien, Villain, Cédric, Vilaire-Meunier, Marie E., Villar-García, Judit, Vincent, Audrey, Van der Linden, Dimitri, Volokha, Alla, Vuotto, Fanny, Wauters, Els, Wu, Alan K.L., Wu, Tak-Chiu, Yahşi, Aysun, Yesilbas, Osman, Yildiz, Mehmet, Young, Barnaby E., Yükselmiş, Ufuk, Zecca, Marco, Zuccaro, Valentina, Van Praet, Jens, Lambrecht, Bart N., Van Braeckel, Eva, Bosteels, Cédric, Hoste, Levi, Hoste, Eric, Bauters, Fré, De Clercq, Jozefien, Heijmans, Catherine, Slabbynck, Hans, Naesens, Leslie, Florkin, Benoit, Young, Mary-Anne, Willis, Amanda, Lapuente-Suanzes, Paloma, de Andrés-Martín, Ana, Berkell, Matilda, Carelli, Valerio, Fiorentino, Alessia, Malhotra, Surbhi, Mattiaccio, Alessandro, Pippucci, Tommaso, Seri, Marco, Tacconelli, Evelina, van Agtmael, Michiel, Algera, Anne Geke, Appelman, Brent, van Baarle, Frank, Bax, Diane, Beudel, Martijn, Bogaard, Harm Jan, Bomers, Marije, Bonta, Peter, Bos, Lieuwe, Botta, Michela, de Brabander, Justin, de Bree, Godelieve, de Bruin, Sanne, Buis, David T.P., Bugiani, Marianna, Bulle, Esther, Chouchane, Osoul, Cloherty, Alex, Dijkstra, Mirjam, Dongelmans, Dave A., Dujardin, Romein W.G., Elbers, Paul, Fleuren, Lucas, Geerlings, Suzanne, Geijtenbeek, Theo, Girbes, Armand, Goorhuis, Bram, Grobusch, Martin P., Hafkamp, Florianne, Hagens, Laura, Hamann, Jorg, Harris, Vanessa, Hemke, Robert, Hermans, Sabine M., Heunks, Leo, Hollmann, Markus, Horn, Janneke, Hovius, Joppe W., de Jong, Menno D., Koning, Rutger, Lim, Endry H.T., van Mourik, Niels, Nellen, Jeaninne, Nossent, Esther J., Paulus, Frederique, Peters, Edgar, Pina-Fuentes, Dan A.I., van der Poll, Tom, Preckel, Bennedikt, Prins, Jan M., Raasveld, Jorinde, Reijnders, Tom, de Rotte, Maurits C.F. J., Schinkel, Michiel, Schultz, Marcus J., Schrauwen, Femke A.P., Schuurmans, Alex, Schuurmans, Jaap, Sigaloff, Kim, Slim, Marleen A., Smeele, Patrick, Smit, Marry, Stijnis, Cornelis S., Stilma, Willemke, Teunissen, Charlotte, Thoral, Patrick, Tsonas, Anissa M., Tuinman, Pieter R., van der Valk, Marc, Veelo, Denise P., Volleman, Carolien, de Vries, Heder, Vught, Lonneke A., van Vugt, Michèle, Wouters, Dorien, Zwinderman, A.H., Brouwer, Matthijs C., Wiersinga, W. Joost, Vlaar, Alexander P.J., Tompkins, Miranda F., Alba, Camille, Hupalo, Daniel N., Rosenberger, John, Sukumar, Gauthaman, Wilkerson, Matthew D., Zhang, Xijun, Lack, Justin, Oler, Andrew J., Dobbs, Kerry, Delmonte, Ottavia M., Danielson, Jeffrey J., Biondi, Andrea, Bettini, Laura Rachele, D’Angiò, Mariella, Beretta, Ilaria, Imberti, Luisa, Sottini, Alessandra, Quaresima, Virginia, Quiros-Roldan, Eugenia, Rossi, Camillo, Castagnoli, Riccardo, Montagna, Daniela, Licari, Amelia, Marseglia, Gian Luigi, Marchal, Astrid, Cirulli, Elizabeth T., Neveux, Iva, Bellos, Evangelos, Thwaites, Ryan S., Schiabor Barrett, Kelly M., Zhang, Yu, Nemes-Bokun, Ivana, Kalinova, Mariya, Catchpole, Andrew, Lack, Justin B., Chiu, Christopher, and Grzymski, Joseph J.
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- 2024
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10. A Review and Discussion of Full-Time Equivalency and Appropriate Compensation Models for an Adult Intensivist in the United States Across Various Base Specialties
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Nurok, Michael, Flynn, Brigid C., Pineton de Chambrun, Marc, Kazemian, Mina, Geiderman, Joel, and Nunnally, Mark E.
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- 2024
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11. Severe infections requiring intensive care unit admission in patients receiving ibrutinib for hematological malignancies: a groupe de recherche respiratoire en réanimation onco-hématologique (GRRR-OH) study
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Baucher, Louise, Lemiale, Virginie, Joseph, Adrien, Wallet, Florent, Pineton de Chambrun, Marc, Ferré, Alexis, Lombardi, Romain, Platon, Laura, Contejean, Adrien, Fuseau, Charline, Calvet, Laure, Pène, Frédéric, Kouatchet, Achille, Mokart, Djamel, Azoulay, Elie, and Lafarge, Antoine
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- 2023
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12. Diagnostic yield, safety and therapeutic consequences of myocardial biopsy in clinically suspected fulminant myocarditis unweanable from mechanical circulatory support
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Marquet, Yann, Hékimian, Guillaume, Lebreton, Guillaume, Kerneis, Mathieu, Rouvier, Philippe, Bay, Pierre, Mathian, Alexis, Bréchot, Nicolas, Chommeloux, Juliette, Petit, Matthieu, Gautier, Melchior, Lefevre, Lucie, Saura, Ouriel, Levy, David, Quentric, Paul, Moyon, Quentin, Ortuno, Sofia, Schmidt, Matthieu, Leprince, Pascal, Luyt, Charles-Edouard, Combes, Alain, and Pineton de Chambrun, Marc
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- 2023
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13. Necrotizing soft tissue infections in critically ill neutropenic patients: a French multicentre retrospective cohort study
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Arrestier, Romain, Chaba, Anis, Mabrouki, Asma, Saccheri, Clément, Canet, Emmanuel, Pineton de Chambrun, Marc, Stoclin, Annabelle, Picard, Muriel, Wallet, Florent, Perier, François, Turpin, Matthieu, Argaud, Laurent, Decavèle, Maxens, Issa, Nahéma, Cadoz, Cyril, Klouche, Kada, Cohen, Johana, Mokart, Djamel, Grouille, Julien, Urbina, Tomas, Hua, Camille, Chosidow, Olivier, Mekontso-Dessap, Armand, Azoulay, Elie, and de Prost, Nicolas
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- 2023
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14. Antibiotic stewardship in the ICU: time to shift into overdrive
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Mokrani, David, Chommeloux, Juliette, Pineton de Chambrun, Marc, Hékimian, Guillaume, and Luyt, Charles-Edouard
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- 2023
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15. Immunomodulating Therapies in Acute Myocarditis and Recurrent/Acute Pericarditis.
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Ammirati, Enrico, Bizzi, Emanuele, Veronese, Giacomo, Groh, Matthieu, Van de Heyning, Caroline, Lehtonen, Jukka, Pineton de Chambrun, Marc, Cereda, Alberto, Picchi, Chiara, Trotta, Lucia, Moslehi, Javid, and Brucato, Antonio
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COVID-19 ,acute myocarditis ,anti-IL-1 therapy ,cardiac sarcoidosis ,corticosteroids ,eosinophilic myocarditis ,immunosuppressive therapy ,pericarditis - Abstract
The field of inflammatory disease of the heart or cardio-immunology is rapidly evolving due to the wider use of non-invasive diagnostic tools able to detect and monitor myocardial inflammation. In acute myocarditis, recent data on the use of immunomodulating therapies have been reported both in the setting of systemic autoimmune disorders and in the setting of isolated forms, especially in patients with specific histology (e.g., eosinophilic myocarditis) or with an arrhythmicburden. A role for immunosuppressive therapies has been also shown in severe cases of coronavirus disease 2019 (COVID-19), a condition that can be associated with cardiac injury and acute myocarditis. Furthermore, ongoing clinical trials are assessing the role of high dosage methylprednisolone in the context of acute myocarditis complicated by heart failure or fulminant presentation or the role of anakinra to treat patients with acute myocarditis excluding patients with hemodynamically unstable conditions. In addition, the explosion of immune-mediated therapies in oncology has introduced new pathophysiological entities, such as immune-checkpoint inhibitor-associated myocarditis and new basic research models to understand the interaction between the cardiac and immune systems. Here we provide a broad overview of evolving areas in cardio-immunology. We summarize the use of new imaging tools in combination with endomyocardial biopsy and laboratory parameters such as high sensitivity troponin to monitor the response to immunomodulating therapies based on recent evidence and clinical experience. Concerning pericarditis, the normal composition of pericardial fluid has been recently elucidated, allowing to assess the actual presence of inflammation; indeed, normal pericardial fluid is rich in nucleated cells, protein, albumin, LDH, at levels consistent with inflammatory exudates in other biological fluids. Importantly, recent findings showed how innate immunity plays a pivotal role in the pathogenesis of recurrent pericarditis with raised C-reactive protein, with inflammasome and IL-1 overproduction as drivers for systemic inflammatory response. In the era of tailored medicine, anti-IL-1 agents such as anakinra and rilonacept have been demonstrated highly effective in patients with recurrent pericarditis associated with an inflammatory phenotype.
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- 2022
16. Epidemiology, clinical presentation, and outcomes of 620 patients with eosinophilia in the intensive care unit
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Gaillet, Antoine, Bay, Pierre, Péju, Edwige, Ait-Oufella, Hafid, Azoulay, Elie, Benchabane, Nacime, Cerf, Charles, Cohen, Yves, de Prost, Nicolas, Faguer, Stanislas, Geri, Guillaume, Grangé, Steven, Kahn, Jean-Emmanuel, Kreitmann, Louis, Larcher, Romaric, Lefèvre, Guillaume, Mabrouki, Asma, Mekonsto-Dessap, Armand, Panel, Kewin, Pène, Frédéric, Pineton de Chambrun, Marc, Quenot, Jean-Pierre, Tandjaoui-Lambiotte, Yacine, Timsit, Jean-Francois, Vieillard-Baron, Antoine, Dargent, Auguste, Herault, Antoine, and Groh, Matthieu
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- 2023
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17. Early renal recovery after acute kidney injury in patients on venoarterial extracorporeal membrane oxygenation: A retrospective study
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Sitbon, Alexandre, Coutrot, Maxime, Montero, Santiago, Chommeloux, Juliette, Lebreton, Guillaume, Huang, Florent, Frapard, Thomas, Assouline, Benjamin, Pineton De Chambrun, Marc, Hekimian, Guillaume, Luyt, Charles Edouard, Combes, Alain, and Schmidt, Matthieu
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- 2023
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18. In-ICU-acquired infections in flare-up systemic rheumatic disease patients receiving immunosuppressant
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Assan, Florence, Bay, Pierre, Mathian, Alexis, Hekimian, Guillaume, Bréchot, Nicolas, Quentric, Paul, Moyon, Quentin, Schmidt, Matthieu, Cohen-Aubart, Fleur, Haroche, Julien, Amoura, Zahir, Luyt, Charles-Edouard, Combes, Alain, and Pineton de Chambrun, Marc
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- 2022
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19. Nicotine patches in patients on mechanical ventilation for severe COVID-19: a randomized, double-blind, placebo-controlled, multicentre trial
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Labro, Guylaine, Tubach, Florence, Belin, Lisa, Dubost, Jean-Louis, Osman, David, Muller, Grégoire, Quenot, Jean-Pierre, Da Silva, Daniel, Zarka, Jonathan, Turpin, Matthieu, Mayaux, Julien, Lamer, Christian, Doyen, Denis, Chevrel, Guillaume, Plantefeve, Gaétan, Demeret, Sophie, Piton, Gaël, Manzon, Cyril, Ochin, Evelina, Gaillard, Raphael, Dautzenberg, Bertrand, Baldacini, Mathieu, Lebbah, Said, Miyara, Makoto, Pineton de Chambrun, Marc, Amoura, Zahir, and Combes, Alain
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- 2022
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20. Intravenous Immunoglobulins Tapering and Withdrawal in Systemic Capillary Leak Syndrome (Clarkson Disease)
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Moyon, Quentin, Pineton de Chambrun, Marc, Gousseff, Marie, Mathian, Alexis, Hie, Miguel, Urbanski, Geoffrey, Verlicchi, Franco, Faguer, Stanislas, Dossier, Antoine, Lega, Jean-Christophe, Riviere, Sophie, Saadoun, David, Graveleau, Julie, Lucchini-Lecomte, Marie-Josée, Christides, Christine, Le Moal, Sylvie, Bibes, Béatrice, Malizia, Giuseppe, Ruivard, Marc, Blaison, Gilles, Alric, Laurent, Agard, Christian, Soubrier, Martin, Viallard, Jean-François, Levesque, Hervé, Rivard, Georges-Etienne, Tieulie, Nathalie, Hot, Arnaud, Lovey, Pierre-Yves, Hanslik, Thomas, Lhote, François, Eble, Vincent, Álvarez Troncoso, Jorge, Aujayeb, Avinash, Quentric, Paul, Taieb, Dov, Cohen-Aubart, Fleur, Lambert, Marc, and Amoura, Zahir
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- 2022
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21. Phenotypic Heterogeneity of Fulminant COVID-19--Related Myocarditis in Adults
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Barhoum, Petra, Pineton de Chambrun, Marc, Dorgham, Karim, Kerneis, Mathieu, Burrel, Sonia, Quentric, Paul, Parizot, Christophe, Chommeloux, Juliette, Bréchot, Nicolas, Moyon, Quentin, Lebreton, Guillaume, Boussouar, Samia, Schmidt, Matthieu, Yssel, Hans, Lefevre, Lucie, Miyara, Makoto, Charuel, Jean-Luc, Marot, Stéphane, Marcelin, Anne-Geneviève, Luyt, Charles-Edouard, Leprince, Pascal, Amoura, Zahir, Montalescot, Gilles, Redheuil, Alban, Combes, Alain, Gorochov, Guy, and Hékimian, Guillaume
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- 2022
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22. Amniotic fluid embolism rescued by venoarterial extracorporeal membrane oxygenation
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Aissi James, Sarah, Klein, Thomas, Lebreton, Guillaume, Nizard, Jacky, Chommeloux, Juliette, Bréchot, Nicolas, Pineton de Chambrun, Marc, Hékimian, Guillaume, Luyt, Charles-Edouard, Levy, Bruno, Kimmoun, Antoine, Combes, Alain, and Schmidt, Matthieu
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- 2022
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23. Herpesviridae lung reactivation and infection in patients with severe COVID-19 or influenza virus pneumonia: a comparative study
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Luyt, Charles-Edouard, Burrel, Sonia, Mokrani, David, Pineton de Chambrun, Marc, Luyt, Domitille, Chommeloux, Juliette, Guiraud, Vincent, Bréchot, Nicolas, Schmidt, Matthieu, Hekimian, Guillaume, Combes, Alain, and Boutolleau, David
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- 2022
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24. Validation of survival prediction models for ECMO in Sars-CoV-2-related acute respiratory distress syndrome
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Moyon, Quentin, Pineton de Chambrun, Marc, Lebreton, Guillaume, Chaieb, Hédi, Combes, Alain, and Schmidt, Matthieu
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- 2022
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25. Correction: Epidemiology, clinical presentation, and outcomes of 620 patients with eosinophilia in the intensive care unit
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Gaillet, Antoine, Bay, Pierre, Péju, Edwige, Ait-Oufella, Hafid, Azoulay, Elie, Benchabane, Nacime, Cerf, Charles, Cohen, Yves, de Prost, Nicolas, Faguer, Stanislas, Geri, Guillaume, Grangé, Steven, Kahn, Jean-Emmanuel, Kreitmann, Louis, Larcher, Romaric, Lefèvre, Guillaume, Mabrouki, Asma, Mekonsto-Dessap, Armand, Panel, Kewin, Pène, Frédéric, Pineton de Chambrun, Marc, Quenot, Jean-Pierre, Tandjaoui-Lambiotte, Yacine, Timsit, Jean-Francois, Vieillard-Baron, Antoine, Dargent, Auguste, Herault, Antoine, and Groh, Matthieu
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- 2023
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26. Ceftazidime/avibactam serum concentration in patients on ECMO
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Curtiaud, Anaïs, primary, Petit, Matthieu, additional, Chommeloux, Juliette, additional, Pineton de Chambrun, Marc, additional, Hekimian, Guillaume, additional, Schmidt, Matthieu, additional, Combes, Alain, additional, and Luyt, Charles-Edouard, additional
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- 2024
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27. Extracorporeal membrane oxygenation for refractory acute eosinophilic pneumonia
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Bay, Pierre, primary, Groh, Matthieu, additional, Gaillet, Antoine, additional, Schmidt, Matthieu, additional, Luyt, Charles-Edouard, additional, Combes, Alain, additional, and Pineton de Chambrun, Marc, additional
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- 2024
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28. Clinical picture, outcomes and predictors of relapse in eosinophilia-associated coronary vasospasm: data from a European multicentric study
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Huang, Florent, primary, Khellaf, Lucas Rémi, additional, Lefèvre, Guillaume, additional, Berti, Alvise, additional, d’Humières, Thomas, additional, Sionis, Alessandro, additional, Ariza Solé, Albert, additional, Bello, Federica, additional, Bermeo Garrido, Juan Andres, additional, Crickx, Etienne, additional, Delvino, Paolo, additional, Emmi, Giacomo, additional, Gaillet, Antoine, additional, Garcia, Gilles, additional, Gavand, Pierre-Edouard, additional, George, Jean-Louis, additional, Gilles, Floriane, additional, Golden, Cécile, additional, de Groote, Pascal, additional, Guffroy, Aurélien, additional, Martis, Nihal, additional, Monti, Sara, additional, Mourlanette, Pierre, additional, Pineton de Chambrun, Marc, additional, Prunier, Fabrice, additional, Regola, Francesca, additional, Seret, Gabriel, additional, Terrier, Benjamin, additional, Tréfond, Ludovic, additional, Souteyrand, Géraud, additional, Varenne, Olivier, additional, Zilio, Filippo, additional, Haziza, Franck, additional, Benamer, Hakim, additional, Kahn, Jean-Emmanuel, additional, Vallée, Alexandre, additional, and Groh, Matthieu, additional
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- 2024
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29. Extracorporeal membrane oxygenation network organisation and clinical outcomes during the COVID-19 pandemic in Greater Paris, France: a multicentre cohort study
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JUVIN, Charles, SCHOELL, Thibault, D'Alessandro, Cosimo, MARIN, Sofica, NARDONE, Nathalie, DEMONDION, Pierre, MEYER, Horacio, BOUNADER, Karl, MOIROUX, Alexander, AKAMKAM, Ali, FADEL, Guillaume, RANDRIANALISOA, Erwan, CUSQUEL, Sébastien, LE GLOAHEC, Patrice, HIRSCHAUER, Elisabeth, MUSQUET, Fabrice, Jego, Pierre-Marie, Guedes, Hélène, Roy, Théophile, Mercereau, Lina, Corvol, Emmanuel, Laboure, Anne, Vilanove, Flore, Peperoni, Marco, Machado, Dariène, Sely, Aly, Fortanier, Marion, Gantois, Séverine, Tran, Emilie, Bosq, Elisabeth, Fontanier, Aurélie, Morin, Alice, Cousin, Jocelyne, Bovagnet, Stéphanie, Luyt, Charles Edouard, Hekimian, Guillaume, Brechot, Nicolas, Pineton de Chambrun, Marc, Desnos, Cyrielle, Chomeloux, Juliette, Arzoine, Jeremy, Guerin, Emmanuelle, Monsel, Antoine, Voiriot, Guillaume, Levy, David, Baron, Elodie, Beurton, Alexandra, Chommeloux, Juliette, Paris, Meng, Nemlaghi, Safaa, Bay, Pierre, Demoule, Alexandre, Guidet, Bertrand, Constantin, Jean Michel, Fartoukh, Muriel, Dres, Martin, Nataf, Patrick, Franchineau, Guillaume, Le Fevre, Lucie, Raffoul, Richard, Alkhoder, Soleiman, Ghodbane, Walid, Pisani, Angelo, Braham, Wael, Bessem Gara, Ali, MORDANT, Pierre, CASTIER, Yves-Hervé, de MONTMOLLIN, Etienne, BOUADMA, Lila, TIMSIT, Jean-François, Langeron, Olivier, de Roux, Quentin, Alessandri, Claire, Arminot-Frémaux, Margot, Clariot, Simon, Dessalle, Thomas, Kudela, Agathe, Ly, André, Meffert, Arnaud, Skripkina, Elena, Fiore, Antonio, Radu, Costin, Dupuy-Montbrun, Eleonora, Latremouille, Christian, Mercier, Olaf, Deleuze, Philippe, STEPHAN, François, Duranteau, Jacques, Richard, Christian, Werner, Marie, Teboul, Jean-Louis, Monnet, Xavier, Debbagh, Hassan, Chapelier, Alain, De Wolf, Julien, Glorion, Matthieu, Pricopi, Ciprian, Cassiano, Francesco, Jacquemin, Sébastien, Tachon, Guillaume, Parquin, François, Zuber, Benjamin, Carriou, Alain, Mira, Jean-Paul, Charpentier, Julien, Pene, Frederic, Nguyen, Lee, Voicu, Sébastian, Deye, Nicolas, Malissin, Isabelle, Sutterlin, Laetitia, Naim, Giulia, Pépin-Lehalleur, Adrien, Mrad, Aymen, Ekhérian, Jean-Michel, Nguyen, Philippe, Sidéris, Georgios, Vodovar, Dominique, Grant, Caroline, Arcelli, Mattéo, Copie, Alban, Errabih, Zaccaria, Gonde, Antoine, Magalhaes, Adèle, Meurisse, Edouard, Nitenberg, Kiyoko, Perault, Arthur, Perrin, Lucile, Renaux, Maxime, Marqué, Sophie, Ensenyat-Martin, Luis, Delpierre, Eric, Duprey, Matthieu, da Silva, Daniel, Verdière, Bruno, Amour, Julien, Clément, Marina, Ollivier, Yves, Morichau-Beauchant, Tristan, Daviaud, Fabrice, Le Breton, Camille, Freita-Ramos, Santiago, Amouretti, Marc, Billiet, Pierre Antoine, Dao, Myriam, Dumont, Louis Marie, Federici, Laura, Gaborieau, Baptiste, Postel-Vinay, Pierre, Vuillard, Constance, Zucman, Noémie, Dreyfuss, Didier, Ricard, Jean Damien, Roux, Damien, Lebreton, Guillaume, Schmidt, Matthieu, Ponnaiah, Maharajah, Folliguet, Thierry, Para, Marylou, Guihaire, Julien, Lansac, Emmanuel, Sage, Edouard, Cholley, Bernard, Mégarbane, Bruno, Cronier, Pierrick, Zarka, Jonathan, Da Silva, Daniel, Besset, Sebastien, Lacombat, Igor, Mongardon, Nicolas, Cerf, Charles, Saiydoun, Gabriel, Sonneville, Romain, Chiche, Jean-Daniel, Longrois, Dan, Combes, Alain, and Leprince, Pascal
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- 2021
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30. Arrhythmia-induced cardiomyopathy: A potentially reversible cause of refractory cardiogenic shock requiring venoarterial extracorporeal membrane oxygenation
- Author
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Hékimian, Guillaume, Paulo, Nicolas, Waintraub, Xavier, Bréchot, Nicolas, Schmidt, Matthieu, Lebreton, Guillaume, Pineton de Chambrun, Marc, Muller, Grégoire, Franchineau, Guillaume, Bourcier, Simon, Nieszkowska, Ania, Masi, Paul, Leprince, Pascal, Combes, Alain, Gandjbakhch, Estelle, and Luyt, Charles-Edouard
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- 2021
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31. It’s Not Just the Prices: Time-Driven Activity-Based Costing for Initiation of Veno-Venous Extracorporeal Membrane Oxygenation at Three International Sites—A Case Review
- Author
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Nurok, Michael, Pellegrino, Vin, Pineton de Chambrun, Marc, Warsh, Jonathan, Young, Meredith, Dong, Erik, Parrish, Neil, Shehab, Syed, Combes, Alain, and Kaplan, Robert S.
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- 2022
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32. Myocarditis, paraparesia and ARDS associated to COVID-19 infection
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Jeantin, Lina, Pichereau, Claire, Pineton de Chambrun, Marc, Ben Hadj Salem, Omar, Hayon, Jan, Loubières, Yann, Landon, Valentin, Alves, Mikael, Barbier, Christophe, Au, Siu Ming, Lima da Silva, Lionel, Combes, Alain, Outin, Hervé, and Jamme, Matthieu
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- 2021
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33. Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome associated with COVID-19: a retrospective cohort study
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Luyt, Charles-Edouard, Hekimian, Guillaume, Brechot, Nicolas, Pineton de Chambrun, Marc, Desnos, Cyrielle, Arzoine, Jeremy, Guerin, Emmanuelle, Schoell, Thibaut, Demondion, Pierre, Juvin, Charles, Nardonne, Nathalie, Marin, Sofica, D'Alessandro, Cossimo, Nguyen, Bao-Long, Quemeneur, Cyril, James, Arthur, Assefi, Mona, Lepere, Victoria, Savary, Guillaume, Gibelin, Aude, Turpin, Matthieu, Elabbadi, Alexandre, Berti, Enora, Vezinet, Corinne, Bonvallot, Harold, Delmotte, Pierre-Romain, De Sarcus, Martin, Du Fayet De La Tour, Charlotte, Abbas, Samia, Maury, Eric, Baudel, Jean-Luc, Lavillegrand, Jean-Remi, Ait Oufella, Hafid, Abdelkrim, Abdelmalek, Urbina, Thomas, Virolle, Sara, Deleris, Robin, Bonny, Vincent, Le Marec, Julien, Mayaux, Julien, Morawiec, Elise, Schmidt, Matthieu, Hajage, David, Lebreton, Guillaume, Monsel, Antoine, Voiriot, Guillaume, Levy, David, Baron, Elodie, Beurton, Alexandra, Chommeloux, Juliette, Meng, Paris, Nemlaghi, Safaa, Bay, Pierre, Leprince, Pascal, Demoule, Alexandre, Guidet, Bertrand, Constantin, Jean Michel, Fartoukh, Muriel, Dres, Martin, and Combes, Alain
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- 2020
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34. Neurological diseases of unknown etiology: Brain-biopsy diagnostic yields and safety
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Carpentier, Alexandre, Capelle, Laurent, Navarro, Soledad, Benveniste, Olivier, Psimaras, Dimitri, Hoang-Xuan, Khê, Delattre, Jean-Yves, Weiss, Nicolas, Marois, Clémence, Benghanem, Sarah, Martin-Duverneuil, Nadine, Leblond, Véronique, Choquet, Sylvain, Luyt, Charles-Edouard, Combes, Alain, Caumes, Eric, Calvez, Vincent, Jary, Aude, Piarroux, Renaud, Aubry, Alexandra, Degos, Vincent, Jacquens, Alice, Papeix, Caroline, Navarro, Vincent, Mathon, Bertrand, Le Joncour, Alexandre, Bielle, Franck, Mokhtari, Karima, Boch, Anne-Laure, Peyre, Matthieu, Amoura, Zahir, Cacoub, Patrice, Younan, Nadia, Demeret, Sophie, Shotar, Eimad, Burrel, Sonia, Fekkar, Arnaud, Robert, Jérôme, Amelot, Aymeric, and Pineton de Chambrun, Marc
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- 2020
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35. One-Year Outcome of Critically Ill Patients With Systemic Rheumatic Disease: A Multicenter Cohort Study
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Larcher, Romaric, Pineton de Chambrun, Marc, Garnier, Fanny, Rubenstein, Emma, Carr, Julie, Charbit, Jonathan, Chalard, Kevin, Mourad, Marc, Amalric, Matthieu, Platon, Laura, Brunot, Vincent, Amoura, Zahir, Jaber, Samir, Jung, Boris, Luyt, Charles-Edouard, and Klouche, Kada
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- 2020
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36. In-Hospital Mortality-Associated Factors in Patients With Thrombotic Antiphospholipid Syndrome Requiring ICU Admission
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Pineton de Chambrun, Marc, Larcher, Romaric, Pène, Frédéric, Argaud, Laurent, Mayaux, Julien, Jamme, Matthieu, Coudroy, Remi, Mathian, Alexis, Gibelin, Aude, Azoulay, Elie, Tandjaoui-Lambiotte, Yacine, Dargent, Auguste, Beloncle, François-Michel, Raphalen, Jean-Herlé, Couteau-Chardon, Amélie, de Prost, Nicolas, Devaquet, Jérôme, Contou, Damien, Gaugain, Samuel, Trouiller, Pierre, Grangé, Steven, Ledochowski, Stanislas, Lemarie, Jérémie, Faguer, Stanislas, Degos, Vincent, Luyt, Charles-Edouard, Combes, Alain, and Amoura, Zahir
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- 2020
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37. Outcomes of severe systemic rheumatic disease patients requiring extracorporeal membrane oxygenation
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Bay, Pierre, Lebreton, Guillaume, Mathian, Alexis, Demondion, Pierre, Desnos, Cyrielle, Chommeloux, Juliette, Hékimian, Guillaume, Bréchot, Nicolas, Nieszkowska, Ania, Schmidt, Matthieu, Cohen-Aubart, Fleur, Leprince, Pascal, Luyt, Charles-Edouard, Amoura, Zahir, Combes, Alain, and Pineton de Chambrun, Marc
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- 2021
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38. Electrical Impedance Tomography Monitoring of Bronchoalveolar Lavage in Patients With Acute Respiratory Distress Syndrome
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Franchineau, Guillaume, Chommeloux, Juliette, Pineton de Chambrun, Marc, Lebreton, Guillaume, Bréchot, Nicolas, Hékimian, Guillaume, Bourcier, Simon, Le Guennec, Loïc, Luyt, Charles-Edouard, Combes, Alain, and Schmidt, Matthieu
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- 2022
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39. Critically Ill Patients with Visceral Nocardia Infection, France and Belgium, 2004-2023.
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Khellaf, Lucas, Lemiale, Virginie, Decavèle, Maxens, Pineton de Chambrun, Marc, Beurton, Alexandra, Kamel, Toufik, Stoclin, Anabelle, Mokart, Djamel, Bruneel, Fabrice, Vigneron, Clara, Kouatchet, Achille, Henry, Benoît, Quenot, Jean-Pierre, Jolly, Grégoire, Issa, Nahema, Bellal, Matthieu, Poissy, Julien, Pichereau, Claire, Schmidt, Julien, and Layios, Nathalie
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NOCARDIOSIS ,CRITICALLY ill ,INTENSIVE care patients ,INTENSIVE care units ,CRITICAL care medicine - Abstract
We studied 50 patients with invasive nocardiosis treated during 2004-2023 in intensive care centers in France and Belgium. Most (65%) died in the intensive care unit or in the year after admission. Nocardia infections should be included in the differential diagnoses for patients in the intensive care setting. [ABSTRACT FROM AUTHOR]
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- 2024
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40. A Diagnosis Can Hide Another: The Value of Brain Biopsy in Neurological Lesion of HIV Patients
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Vitelli, Mariano, Mazelle, Henri, Joncour, Alexandre LE, Amelot, Aymeric, Pineton DE Chambrun, Marc, and Mathon, Bertrand
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- 2020
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41. A Diagnosis Can Hide Another: The Value of Brain Biopsy in Neurological Lesion of HIV Patients
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Vitelli, Mariano, Malaizé, Henri, Bielle, Franck, Le Joncour, Alexandre, Amelot, Aymeric, Pineton de Chambrun, Marc, and Mathon, Bertrand
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- 2021
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42. Ventilator-associated pneumonia in patients with SARS-CoV-2-associated acute respiratory distress syndrome requiring ECMO: a retrospective cohort study
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Luyt, Charles-Edouard, Sahnoun, Tarek, Gautier, Melchior, Vidal, Pauline, Burrel, Sonia, Pineton de Chambrun, Marc, Chommeloux, Juliette, Desnos, Cyrielle, Arzoine, Jeremy, Nieszkowska, Ania, Bréchot, Nicolas, Schmidt, Matthieu, Hekimian, Guillaume, Boutolleau, David, Robert, Jérôme, Combes, Alain, and Chastre, Jean
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- 2020
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43. A 24/7 Pilot Remote Emergency Multidisciplinary Discussion for Rapidly Progressive Interstitial Lung Disease: A 2-Year Experience
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Bay, Pierre, Pineton de Chambrun, Marc, Allenbach, Yves, Le Pavec, Jérôme, Picard, Clément, Zuber, Benjamin, Bunel, Vincent, Hervier, Baptiste, Meyer, Alain, Miyara, Makoto, Brillet, Pierre-Yves, Boussouar, Samia, Declercq, Christelle, Tandjaoui-Lambiotte, Yacine, Nunes, Hilario, Cottin, Vincent, Hachulla, Eric, and Uzunhan, Yurdagül
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- 2024
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- View/download PDF
44. Corrigendum to “Pharmacokinetics/pharmacodynamics of ceftobiprole in patients on extracorporeal membrane oxygenation” [International Journal of Antimicrobial Agents Volume 61 (2023)106765]
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Coppens, Alexandre, primary, Zahr, Noël, additional, Chommeloux, Juliette, additional, Bleibtreu, Alexandre, additional, Hekimian, Guillaume, additional, Pineton de Chambrun, Marc, additional, LeFevre, Lucie, additional, Schmidt, Matthieu, additional, Robert, Jérôme, additional, Junot, Helga, additional, Combes, Alain, additional, and Luyt, Charles-Edouard, additional
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- 2023
- Full Text
- View/download PDF
45. Pharmacokinetics/pharmacodynamics of ceftobiprole in patients on extracorporeal membrane oxygenation
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Coppens, Alexandre, primary, Zahr, Noël, additional, Chommeloux, Juliette, additional, Bleibtreu, Alexandre, additional, Hekimian, Guillaume, additional, Pineton de Chambrun, Marc, additional, LeFevre, Lucie, additional, Schmidt, Matthieu, additional, Robert, Jérôme, additional, Junot, Helga, additional, Combes, Alain, additional, and Luyt, Charles-Edouard, additional
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- 2023
- Full Text
- View/download PDF
46. Abatacept/Ruxolitinib and Screening for Concomitant Respiratory Muscle Failure to Mitigate Fatality of Immune-Checkpoint Inhibitor Myocarditis.
- Author
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Salem, Joe-Elie, Salem, Joe-Elie, Bretagne, Marie, Abbar, Baptiste, Leonard-Louis, Sarah, Ederhy, Stephane, Redheuil, Alban, Boussouar, Samia, Nguyen, Lee S, Procureur, Adrien, Stein, Frederic, Fenioux, Charlotte, Devos, Perrine, Gougis, Paul, Dres, Martin, Demoule, Alexandre, Psimaras, Dimitri, Lenglet, Timothee, Maisonobe, Thierry, Pineton DE Chambrun, Marc, Hekimian, Guillaume, Straus, Christian, Gonzalez-Bermejo, Jesus, Klatzmann, David, Rigolet, Aude, Guillaume-Jugnot, Perrine, Champtiaux, Nicolas, Benveniste, Olivier, Weiss, Nicolas, Saheb, Samir, Rouvier, Philippe, Plu, Isabelle, Gandjbakhch, Estelle, Kerneis, Mathieu, Hammoudi, Nadjib, Zahr, Noel, Llontop, Claudia, Morelot-Panzini, Capucine, Lehmann, Lorenz, Qin, Juan, Moslehi, Javid J, Rosenzwajg, Michelle, Similowski, Thomas, Allenbach, Yves, Salem, Joe-Elie, Salem, Joe-Elie, Bretagne, Marie, Abbar, Baptiste, Leonard-Louis, Sarah, Ederhy, Stephane, Redheuil, Alban, Boussouar, Samia, Nguyen, Lee S, Procureur, Adrien, Stein, Frederic, Fenioux, Charlotte, Devos, Perrine, Gougis, Paul, Dres, Martin, Demoule, Alexandre, Psimaras, Dimitri, Lenglet, Timothee, Maisonobe, Thierry, Pineton DE Chambrun, Marc, Hekimian, Guillaume, Straus, Christian, Gonzalez-Bermejo, Jesus, Klatzmann, David, Rigolet, Aude, Guillaume-Jugnot, Perrine, Champtiaux, Nicolas, Benveniste, Olivier, Weiss, Nicolas, Saheb, Samir, Rouvier, Philippe, Plu, Isabelle, Gandjbakhch, Estelle, Kerneis, Mathieu, Hammoudi, Nadjib, Zahr, Noel, Llontop, Claudia, Morelot-Panzini, Capucine, Lehmann, Lorenz, Qin, Juan, Moslehi, Javid J, Rosenzwajg, Michelle, Similowski, Thomas, and Allenbach, Yves
- Abstract
Immune-checkpoint-inhibitor (ICI)-associated myotoxicity involves the heart (myocarditis) and skeletal muscles (myositis), which frequently occur concurrently and is highly fatal. We report the results of a strategy that included identification of individuals with severe ICI-myocarditis by also screening for and managing concomitant respiratory muscle involvement with mechanical ventilation, as well as treatment with CTLA4-fusion protein abatacept and the Janus-kinase inhibitor ruxolitinib. Forty cases with definite ICI-myocarditis were included with pathological confirmation of concomitant myositis in the majority of patients. In the first 10 patients, using recommended guidelines, myotoxicity-related fatality occurred in 60%, consistent with historical controls. In the subsequent 30 cases, we instituted systematic screening for respiratory muscle involvement coupled with active ventilation and treatment using ruxolitinib and abatacept. Abatacept dose was adjusted using CD86-receptor occupancy on circulating monocytes. Myotoxicity-related fatality rate was 3.4%(1/30) in these 30 patients vs.60% in 1st quartile(p<0.0001). These clinical results are hypothesis-generating and need further evaluation.
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- 2023
47. Bleeding and thrombotic events in patients with severe COVID-19 supported with extracorporeal membrane oxygenation: a nationwide cohort study
- Author
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Mansour, Alexandre, Flecher, Erwan, Schmidt, Matthieu, Rozec, Bertrand, Gouin-Thibault, Isabelle, Esvan, Maxime, Fougerou, Claire, Levy, Bruno, Porto, Alizée, Ross, James, Para, Marylou, Manganiello, Sabrina, Lebreton, Guillaume, Vincentelli, André, Nesseler, Nicolas, Pierrot, Marc, Chocron, Sidney, Flicoteaux, Guillaume, Mauriat, Philippe, Ouattara, Alexandre, Roze, Hadrien, Huet, Olivier, Fischer, Marc-Olivier, Alessandri, Claire, Bellaïche, Raphel, Constant, Ophélie, de Roux, Quentin, Ly, André, Meffert, Arnaud, Merle, Jean-Claude, Mongardon, Nicolas, Picard, Lucile, Skripkina, Elena, Folliguet, Thierry, Fiore, Antonio, D’ostrevy, Nicolas, Morgan, Marie-Catherine, Guinot, Pierre-Grégoire, Nguyen, Maxime, Gaide-Chevronnay, Lucie, Terzi, Nicolas, Colin, Gwenhaël, Fabre, Olivier, Astaneh, Arash, Issard, Justin, Fadel, Elie, Fabre, Dominique, Girault, Antoine, Guihaire, Julien, Ion, Iolande, Menager, Jean Baptiste, Mitilian, Delphine, Mercier, Olaf, Stephan, François, Thes, Jacques, Jouan, Jerôme, Duburcq, Thibault, Loobuyck, Valentin, Moussa, Mouhammed, Mugnier, Agnes, Rousse, Natacha, Desebbe, Olivier, Fellahi, Jean-Luc, Henaine, Roland, Pozzi, Matteo, Richard, Jean-Christophe, Riad, Zakaria, Guervilly, Christophe, Hraiech, Sami, Papazian, Laurent, Castanier, Matthias, Chanavaz, Charles, Cadoz, Cyril, Gette, Sebastien, Louis, Guillaume, Portocarrero, Erick, Gaudard, Philippe, Brini, Kais, Bischoff, Nicolas, Kimmoun, Antoine, Mattei, Mathieu, Perez, Pierre, Bourdiol, Alexandre, Hourmant, Yannick, Mahé, Pierre-Joachim, Jaquet, Pierre, Lortat-Jacob, Brice, Mordant, Pierre, Nataf, Patrick, Patrier, Juliette, Provenchère, Sophie, Roué, Morgan, Sonneville, Romain, Tran-Dinh, Alexy, Wicky, Paul-Henri, Al Zreibi, Charles, Cholley, Bernard, Guyonvarch, Yannis, Hamada, Sophie, Harrois, Anatole, Matiello, Jordi, Kerforne, Thomas, Lacroix, Corentin, Brechot, Nicolas, Combes, Alain, Chommeloux, Juliette, Constantin, Jean Michel, D’alessandro, Cosimo, Demondion, Pierre, Demoule, Alexandre, Dres, Martin, Fadel, Guillaume, Fartoukh, Muriel, Hekimian, Guillaume, Juvin, Charles, Leprince, Pascal, Levy, David, Luyt, Charles Edouard, Pineton de Chambrun, Marc, Schoell, Thibaut, Fillâtre, Pierre, Massart, Nicolas, Nicolas, Roxane, Jonas, Maud, Vidal, Charles, Allou, Nicolas, Muccio, Salvatore, Di Perna, Dario, Ruggieri, Vito-Giovanni, Mourvillier, Bruno, Anselmi, Amedeo, Bounader, Karl, Launey, Yoann, Lebouvier, Thomas, Parasido, Alessandro, Reizine, Florian, Seguin, Philippe, Besnier, Emmanuel, Carpentier, Dorothée, Clavier, Thomas, Falcoz, Pierre-Emmanuel, Olland, Anne, Villard, Marion, Bounes, Fanny, Labaste, François, Minville, Vincent, Guillon, Antoine, Fedun, Yannick, CHU Pontchaillou [Rennes], Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Hôpital Guillaume-et-René-Laennec [Saint-Herblain], Défaillance Cardiovasculaire Aiguë et Chronique (DCAC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Service de Réanimation Médicale [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Hôpital de la Timone [CHU - APHM] (TIMONE), University of California [Davis] (UC Davis), University of California (UC), Laboratoire de Recherche Vasculaire Translationnelle (LVTS (UMR_S_1148 / U1148)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), CHU Lille, Institut de cardiologie [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Récepteurs Nucléaires, Maladies Métaboliques et Cardiovasculaires - U1011 (RNMCD), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Nutrition, Métabolismes et Cancer (NuMeCan), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), and This work was supported by a grant from the university hospital of Rennes (Appel à projets CFTR2) and by a grant from the French society of thoracic and cardio-vascular surgery (Société française de chirurgie thoracique et cardio-vasculaire, Bourse Marc Laskar).
- Subjects
Anticoagulation ,[SDV]Life Sciences [q-bio] ,Bleeding ,COVID-19 ,Thrombosis ,ECMO ,Critical Care and Intensive Care Medicine - Abstract
International audience; Purpose: To describe bleeding and thrombotic events and their risk factors in patients receiving extracorporeal membrane oxygenation (ECMO) for severe coronavirus disease 2019 (COVID-19) and to evaluate their impact on in-hospital mortality.Methods: The ECMOSARS registry included COVID-19 patients supported by ECMO in France. We analyzed all patients included up to March 31, 2022 without missing data regarding bleeding and thrombotic events. The association of bleeding and thrombotic events with in-hospital mortality and pre-ECMO variables was assessed using multivariable logistic regression models.Results: Among 620 patients supported by ECMO, 29% had only bleeding events, 16% only thrombotic events and 20% both bleeding and thrombosis. Cannulation site (18% of patients), ear nose and throat (12%), pulmonary bleeding (9%) and intracranial hemorrhage (8%) were the most frequent bleeding types. Device-related thrombosis and pulmonary embolism/thrombosis accounted for most of thrombotic events. In-hospital mortality was 55.7%. Bleeding events were associated with in-hospital mortality (adjusted odds ratio (adjOR) = 2.91[1.94-4.4]) but not thrombotic events (adjOR = 1.02[0.68-1.53]). Intracranial hemorrhage was strongly associated with in-hospital mortality (adjOR = 13.5[4.4-41.5]). Ventilation duration before ECMO ≥ 7 days and length of ECMO support were associated with bleeding. Thrombosis-associated factors were fibrinogen ≥ 6 g/L and length of ECMO support.Conclusions: In a nationwide cohort of COVID-19 patients supported by ECMO, bleeding incidence was high and associated with mortality. Intracranial hemorrhage incidence was higher than reported for non-COVID patients and carried the highest risk of death. Thrombotic events were less frequent and not associated with mortality. Length of ECMO support was associated with a higher risk of both bleeding and thrombosis, supporting the development of strategies to minimize ECMO duration.
- Published
- 2022
48. Systemic Inflammatory Response Syndrome Is a Major Contributor to COVID-19–Associated Coagulopathy: Insights From a Prospective, Single-Center Cohort Study
- Author
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Masi, Paul, Hékimian, Guillaume, Lejeune, Manon, Chommeloux, Juliette, Desnos, Cyrielle, Pineton De Chambrun, Marc, Martin-Toutain, Isabelle, Nieszkowska, Ania, Lebreton, Guillaume, Bréchot, Nicolas, Schmidt, Matthieu, Edouard Luyt, Charles, Combes, Alain, and Frere, Corinne
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- 2020
- Full Text
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49. The place of extracorporeal life support in cardiogenic shock
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Pineton de Chambrun, Marc, Bréchot, Nicolas, and Combes, Alain
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- 2020
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50. Early Reversal of Right Ventricular Dysfunction after Venovenous Extracorporeal Membrane Oxygenation in Patients with COVID-19 Pneumonia
- Author
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Levy, David, primary, Desnos, Cyrielle, additional, Lebreton, Guillaume, additional, Théry, Guillaume, additional, Pineton de Chambrun, Marc, additional, Leprince, Pascal, additional, Hammoudi, Nadjib, additional, Schmidt, Matthieu, additional, Combes, Alain, additional, and Hékimian, Guillaume, additional
- Published
- 2023
- Full Text
- View/download PDF
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