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2. ANMCO/SICI-GISE/SIC/SIECVI/SIRM Consensus document: Appropriateness of multimodality imaging in cardiovascular disease [Documento di consenso ANMCO/SICI-GISE/SIC/SIECVI/SIRM: Appropriatezza dell’imaging multimodale nelle patologie cardiovascolari]

Author

Nardi, F, Pino, P, Gabrielli, D, Colivicchi, F, Abrignani, M, Amico, A, Aspromonte, N, Benedetto, F, Bertella, E, Boccardi, L, Bucciarelli Ducci, C, Caldarola, P, Campana, M, Caso, P, Citro, R, Costante, A, De Chiara, B, Di Cesare, E, Di Fusco, S, Domenicucci, S, Enea, I, Erba, P, Faganello, G, Favilli, S, Geraci, G, Giubbini, R, Giunta, N, Guido, V, Imazio, M, Khoury, G, La Canna, G, Mele, D, Moreo, A, Mercuro, G, Musumeci, G, Neglia, D, Parrini, I, Pinamonti, B, Pollarolo, L, Pontone, G, Privitera, C, Riccio, C, Sinagra, G, Urbinati, S, Varbella, F, Berisso, M, Zuin, G, Di Lenarda, A, Gulizia, M, Nardi F., Pino P. G., Gabrielli D., Colivicchi F., Abrignani M. G., Amico A. F., Aspromonte N., Benedetto F. A., Bertella E., Boccardi L. M., Bucciarelli Ducci C., Caldarola P., Campana M., Caso P., Citro R., Costante A. M., De Chiara B. C., Di Cesare E., Di Fusco S. A., Domenicucci S., Enea I., Erba P., Faganello G., Favilli S., Geraci G., Giubbini R., Giunta N., Guido V., Imazio M., Khoury G., La Canna G., Mele D., Moreo A. M., Mercuro G. G., Musumeci G., Neglia D., Parrini I., Pinamonti B., Pollarolo L., Pontone G., Privitera C., Riccio C., Sinagra G., Urbinati S., Varbella F., Berisso M. Z., Zuin G., Di Lenarda A., Gulizia M. M., Nardi, F, Pino, P, Gabrielli, D, Colivicchi, F, Abrignani, M, Amico, A, Aspromonte, N, Benedetto, F, Bertella, E, Boccardi, L, Bucciarelli Ducci, C, Caldarola, P, Campana, M, Caso, P, Citro, R, Costante, A, De Chiara, B, Di Cesare, E, Di Fusco, S, Domenicucci, S, Enea, I, Erba, P, Faganello, G, Favilli, S, Geraci, G, Giubbini, R, Giunta, N, Guido, V, Imazio, M, Khoury, G, La Canna, G, Mele, D, Moreo, A, Mercuro, G, Musumeci, G, Neglia, D, Parrini, I, Pinamonti, B, Pollarolo, L, Pontone, G, Privitera, C, Riccio, C, Sinagra, G, Urbinati, S, Varbella, F, Berisso, M, Zuin, G, Di Lenarda, A, Gulizia, M, Nardi F., Pino P. G., Gabrielli D., Colivicchi F., Abrignani M. G., Amico A. F., Aspromonte N., Benedetto F. A., Bertella E., Boccardi L. M., Bucciarelli Ducci C., Caldarola P., Campana M., Caso P., Citro R., Costante A. M., De Chiara B. C., Di Cesare E., Di Fusco S. A., Domenicucci S., Enea I., Erba P., Faganello G., Favilli S., Geraci G., Giubbini R., Giunta N., Guido V., Imazio M., Khoury G., La Canna G., Mele D., Moreo A. M., Mercuro G. G., Musumeci G., Neglia D., Parrini I., Pinamonti B., Pollarolo L., Pontone G., Privitera C., Riccio C., Sinagra G., Urbinati S., Varbella F., Berisso M. Z., Zuin G., Di Lenarda A., and Gulizia M. M.

Abstract

The complexity of cardiovascular diseases has led to an extensive use of technological instruments and the development of multimodality imaging. This extensive use of different cardiovascular imaging tests in the same patient has increased costs and waiting times.The concept of appropriateness has changed over time. Appropriateness criteria address the need for specific cardiovascular imaging tests in well-defined clinical scenarios, and define the kind of cardiovascular imaging that is appropriated for each clinical scenario in different stages of the disease. The concept of appropriateness criteria has replaced the old idea of appropriate use criteria and reflects the increasing effort of the international Scientific Societies to create and review in a critical way the management of diagnostic tests used by clinicians.The aim of this Italian consensus document is to address the use of multimodality imaging in the diagnosis and management of the major cardiovascular clinical scenarios, taking into consideration not only the international guidelines and scientific documents already published, but also the reality of Italian laws as well as the various professional profiles involved in patient management and availability of technological diagnostic instruments.

Published
2020

8. Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function

Author

Zacchigna, S, Paldino, A, Falcao-Pires, I, Daskalopoulos, EP, Dal Ferro, M, Vodret, S, Lesizza, P, Cannata, A, Miranda-Silva, D, Lourenco, A P, Pinamonti, B, Sinagra, G, Weinberger, F, Eschenhagen, T, Carrier, L, Kehat, I, Tocchetti, CG, Russo, M, Ghigo, A, Cimino, J, Hirsch, E, Dawson, D, Ciccarelli, M, Oliveti, M, Linke, WA, Cuijpers, I, Heymans, S, Hamdani, N, Boer, Monique, Duncker, Dirk-jan, Kuster, D, Velden, J, Beauloye, C, Bertrand, L, Mayr, M, Giacca, M, Leuschner, F, Backs, J, Thum, T, Zacchigna, S, Paldino, A, Falcao-Pires, I, Daskalopoulos, EP, Dal Ferro, M, Vodret, S, Lesizza, P, Cannata, A, Miranda-Silva, D, Lourenco, A P, Pinamonti, B, Sinagra, G, Weinberger, F, Eschenhagen, T, Carrier, L, Kehat, I, Tocchetti, CG, Russo, M, Ghigo, A, Cimino, J, Hirsch, E, Dawson, D, Ciccarelli, M, Oliveti, M, Linke, WA, Cuijpers, I, Heymans, S, Hamdani, N, Boer, Monique, Duncker, Dirk-jan, Kuster, D, Velden, J, Beauloye, C, Bertrand, L, Mayr, M, Giacca, M, Leuschner, F, Backs, J, and Thum, T

Abstract

Echocardiography is a reliable and reproducible method to assess non-invasively cardiac function in clinical and experimental research. Significant progress in the development of echocardiographic equipment and transducers has led to the successful translation of this methodology from humans to rodents, allowing for the scoring of disease severity and progression, testing of new drugs, and monitoring cardiac function in genetically modified or pharmacologically treated animals. However, as yet, there is no standardization in the procedure to acquire echocardiographic measurements in small animals. This position paper focuses on the appropriate acquisition and analysis of echocardiographic parameters in adult mice and rats, and provides reference values, representative images, and videos for the accurate and reproducible quantification of left ventricular function in healthy and pathological conditions.

Published
2021

16. Impact on clinical outcomes of right ventricular response to percutaneous correction of secondary mitral regurgitation

Author

Caiffa, T, primary, Castrichini, M, additional, Biagini, E, additional, De Luca, A, additional, Compagnone, M, additional, Berardini, A, additional, Merlo, M, additional, Fabris, E, additional, Vitrella, G, additional, Pinamonti, B, additional, Korcova, R, additional, Barbati, G, additional, Saia, F, additional, Stolfo, D, additional, and Sinagra, G, additional

Published
2021
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26. 1040 Unexpected prevalence of subtle systolic and diastolic dysfunction in genotype-positive phenotype-negative relatives of dilated cardiomyopathy patients

Author

Paldino, A, primary, De Angelis, G, additional, Dal Ferro, M, additional, Faganello, G, additional, Porcari, A, additional, Barbati, G, additional, Korcova, R, additional, Gentile, P, additional, Artico, J, additional, Pinamonti, B, additional, Merlo, M, additional, and Sinagra, G, additional

Published
2020
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27. Strain analysis reveals subtle systolic dysfunction in confirmed and suspected myocarditis with normal LVEF. A cardiac magnetic resonance study

Author

Porcari, A., primary, Merlo, M., additional, Crosera, L., additional, Stolfo, D., additional, Barbati, G., additional, Biondi, F., additional, De Angelis, G., additional, Paldino, A., additional, Pagnan, L., additional, Belgrano, M., additional, Cova, M. A., additional, Pinamonti, B., additional, Vitrella, G., additional, and Sinagra, G., additional

Published
2019
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29. Left ventricular dysfunction and outcome at two-year follow-up in patients with type 2 diabetes: The DYDA study

Author

Cioffi G, Faggiano P, Lucci D, Maggioni AP, Manicardi V, Travaglini A, Girfoglio D, Masson S, Giorda CB, Velussi M, Di Lenarda A, Verdecchia P, Comaschi M. DYDA Investigators Collaborators Comaschi M, Giorda C, Tarantini L, de Simone G, Mureddu G, Comaschi M, Latini R, Vago T, Angeli F, Mazzotta G, Repaci S, Botta I, Casalnuovo G, Chinali M, Boemi M, Mocchegiani R, Corsi A, Ponzani P, Camerini A, Pinamonti B, Grosu A, Sforza A, Rambaldi R, Zarra E, Murtas MG, Montaldo C, Motta RM, Leonardi G, Marchese T, Brero ML, Magro G, Tanga M, Rotella CM, Lenuzza M, Baggiore CM, Leopardi A, Minneci C, Sulla A, De Micheli A, Papagna D, Maggi D, Spallarossa P, Aglialoro A, Magaja O, Sabbatini G, Cesareo F, Corda A, Pitzalis L, Masselli L, Midi P, Pontiroli AE, Mauri C, Carletti F, Piatti P, Agricola E, Donà G, Frigato N, Finardi L, Catellani E, Piazza A, Cozzolino D, Madau G, Scanu M, Reboldi G, Biagioli P, Arcangeli A, Marsocci A, Badia T, Dabizzi L, Trojani C, Amati S, Genovese S, Bragato RM, Vespasiani G, Galetta M, Floris F, Mastroianno S, Russo A, De Cosmo S, Sturaro R, Ubaldi S, Miselli V, Gambarati GP, Curci V, Mattioli R, Mezzetti P, Bovelli D, Limone P, Mabritto B, Fonda M, Manca E, Pinamonti B., GENTILE, Sandro, Cioffi, G, Faggiano, P, Lucci, D, Maggioni, Ap, Manicardi, V, Travaglini, A, Girfoglio, D, Masson, S, Giorda, Cb, Velussi, M, Di Lenarda, A, Verdecchia, P, Comaschi M., DYDA Investigators Collaborators Comaschi M, Giorda, C, Tarantini, L, de Simone, G, Mureddu, G, Comaschi, M, Latini, R, Vago, T, Angeli, F, Mazzotta, G, Repaci, S, Botta, I, Casalnuovo, G, Chinali, M, Boemi, M, Mocchegiani, R, Corsi, A, Ponzani, P, Camerini, A, Pinamonti, B, Grosu, A, Sforza, A, Rambaldi, R, Zarra, E, Murtas, Mg, Montaldo, C, Motta, Rm, Leonardi, G, Marchese, T, Brero, Ml, Magro, G, Tanga, M, Rotella, Cm, Lenuzza, M, Baggiore, Cm, Leopardi, A, Minneci, C, Sulla, A, De Micheli, A, Papagna, D, Maggi, D, Spallarossa, P, Aglialoro, A, Magaja, O, Sabbatini, G, Cesareo, F, Corda, A, Pitzalis, L, Masselli, L, Midi, P, Pontiroli, Ae, Mauri, C, Carletti, F, Piatti, P, Agricola, E, Donà, G, Frigato, N, Finardi, L, Catellani, E, Piazza, A, Gentile, Sandro, Cozzolino, D, Madau, G, Scanu, M, Reboldi, G, Biagioli, P, Arcangeli, A, Marsocci, A, Badia, T, Dabizzi, L, Trojani, C, Amati, S, Genovese, S, Bragato, Rm, Vespasiani, G, Galetta, M, Floris, F, Mastroianno, S, Russo, A, De Cosmo, S, Sturaro, R, Ubaldi, S, Miselli, V, Gambarati, Gp, Curci, V, Mattioli, R, Mezzetti, P, Bovelli, D, Limone, P, Mabritto, B, Fonda, M, Manca, E, and Pinamonti, B.

Abstract

Left ventricular dysfunction (LVD) in type 2 diabetes mellitus (DM) (DYDA) study is a prospective investigation enrolling 960 with DM without overt cardiac disease. At baseline, a high prevalence of LVD was detected by analysing midwall shortening. We report here the incidence of clinical events in DYDA patients after 2-year follow-up and the frequency of LVD detected at baseline and 2-year evaluation. METHODS: Systolic LVD was defined as midwall shortening ≤15%, diastolic LVD as any condition different from "normal diastolic function" identified as E/A ratio on Doppler mitral flow between 0.75 and 1.5 and deceleration time of E wave >140 ms. Major outcome was a composite of major events, including all-causes death and hospital admissions. RESULTS: During the study period, any systolic/diastolic LVD was found in 616 of 699 patients (88.1%) in whom LVD function could be measured at baseline or at 2 years. Older age and high HbA1c predicted the occurrence of LVD. During the follow-up 15 patients died (1.6%), 3 for cardiovascular causes, 139 were hospitalized (14.5%, 43 of them for cardiovascular causes, 20 for a new cancer). CONCLUSIONS: During a 2-year follow-up any LVD is detectable in a large majority of patients with DM without overt cardiac disease. Older age and higher HbA1c predict LVD. All-cause death or hospitalization occurred in 15% of patients, cardiovascular cause was uncommon. Independent predictors of events were older age, pathologic lipid profile, high HbA1c, claudicatio and repaglinide therapy. Echo-assessed LVD at baseline was not prognosticator of events. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Published
2013

30. Analysis of midwall shortening reveals high prevalence of left ventricular myocardial dysfunction in patients with diabetes mellitus: the DYDA study

Author

Cioffi G, Giorda CB, Chinali M, Di Lenarda A, Faggiano P, Lucci D, Maggioni AP, Masson S, Mureddu GF, Tarantini L, Velussi M, Comaschi M, DYDA I.n.v.e.s.t.i.g.a.t.o.r.s. Collaborators Comaschi M, Giorda C, de Simone G, Mureddu G, Verdecchia P, Latini R, Vago T, Angeli F, Mazzotta G, Repaci S, Botta I, Casalnuovo G, Girfoglio D, Boemi M, Mocchegiani R, Corsi A, Ponzani P, Camerini A, Pinamonti B, Grosu A, Sforza A, Rambaldi R, Zarra E, Murtas MG, Montaldo C, Motta RM, Leonardi G, Marchese T, Brero ML, Magro G, Tanga M, Rotella CM, Lenuzza M, Baggiore CM, Leopardi A, Minneci C, Sulla A, De Micheli A, Papagna D, Maggi D, Spallarossa P, Aglialoro A, Magaja O, Sabbatini G, Cesareo F, Corda A, Pitzalis L, Masselli L, Midi P, Pontiroli AE, Mauri C, Carletti F, Piatti P, Agricola E, Donà G, Frigato N, Manicardi V, Finardi L, Catellani E, Piazza A, Cozzolino D, Madau G, Scanu M, Reboldi G, Biagioli P, Arcangeli A, Marsocci A, Badia T, Dabizzi L, Trojani C, Amati S, Genovese S, Bragato RM, Vespasiani G, Galetta M, Floris F, Mastroianno S, Russo A, De Cosmo S, Sturaro R, Ubaldi S, Miselli V, Gambarati GP, Curci V, Mattioli R, Travaglini A, Mezzetti P, Bovelli D, Limone P, Mabritto B, Fonda M, Manca E, Pinamonti B., GENTILE, Sandro, Cioffi, G, Giorda, Cb, Chinali, M, Di Lenarda, A, Faggiano, P, Lucci, D, Maggioni, Ap, Masson, S, Mureddu, Gf, Tarantini, L, Velussi, M, Comaschi, M, Collaborators Comaschi M, DYDA I. n. v. e. s. t. i. g. a. t. o. r. s., Giorda, C, de Simone, G, Mureddu, G, Verdecchia, P, Latini, R, Vago, T, Angeli, F, Mazzotta, G, Repaci, S, Botta, I, Casalnuovo, G, Girfoglio, D, Boemi, M, Mocchegiani, R, Corsi, A, Ponzani, P, Camerini, A, Pinamonti, B, Grosu, A, Sforza, A, Rambaldi, R, Zarra, E, Murtas, Mg, Montaldo, C, Motta, Rm, Leonardi, G, Marchese, T, Brero, Ml, Magro, G, Tanga, M, Rotella, Cm, Lenuzza, M, Baggiore, Cm, Leopardi, A, Minneci, C, Sulla, A, De Micheli, A, Papagna, D, Maggi, D, Spallarossa, P, Aglialoro, A, Magaja, O, Sabbatini, G, Cesareo, F, Corda, A, Pitzalis, L, Masselli, L, Midi, P, Pontiroli, Ae, Mauri, C, Carletti, F, Piatti, P, Agricola, E, Donà, G, Frigato, N, Manicardi, V, Finardi, L, Catellani, E, Piazza, A, Gentile, Sandro, Cozzolino, D, Madau, G, Scanu, M, Reboldi, G, Biagioli, P, Arcangeli, A, Marsocci, A, Badia, T, Dabizzi, L, Trojani, C, Amati, S, Genovese, S, Bragato, Rm, Vespasiani, G, Galetta, M, Floris, F, Mastroianno, S, Russo, A, De Cosmo, S, Sturaro, R, Ubaldi, S, Miselli, V, Gambarati, Gp, Curci, V, Mattioli, R, Travaglini, A, Mezzetti, P, Bovelli, D, Limone, P, Mabritto, B, Fonda, M, Manca, E, and Pinamonti, B.

Abstract

Individuals with diabetes mellitus (DM) have a higher risk to develop heart failure. Clinical guidelines emphasize the importance of early diagnosis of left ventricular dysfunction (LVD) and preventive interventions in these patients. In this study we assessed the prevalence of LVD, systolic or diastolic, in DM patients without known cardiac disease recruited in the 'left ventricular DYsfunction in DiAbetes (DYDA)' study. DESIGN AND METHODS: We performed clinical, ECG, laboratory, and echocardiographic exams in 960 patients (61 ± 8 years, 59% hypertensive) recruited in the DYDA study from 37 Italian diabetes referral centres. ECG and echo exams were read in central facilities. Systolic LVD was defined as ejection fraction ≤ 50% or midwall shortening (MFS) ≤ 15%. Diastolic LVD was identified when transmitral E/A was out of the range of 0.75-1.5 or deceleration time of mitral E wave ≤ 140 msec. RESULTS: Echocardiographic data were obtained in 751 patients (78.2%). Isolated systolic LVD was detected in 22.0% of patients, isolated diastolic LVD in 21.5%, and combined systolic and diastolic LVD in 12.7%. All patients with systolic LVD had MFS ≤ 15%, while only 9% had an ejection fraction ≤ 50%. Higher LV mass, relative wall thickness, prevalence of concentric geometry, and LV hypertrophy characterized the patients with LVD. CONCLUSIONS: LVD is present in more than half of DM patients without clinically detectable cardiac disease and is associated with LV hypertrophy and concentric LV geometry. One-third of patients exhibits systolic LVD detectable at the midwall level.

Published
2012

31. Inappropriately high left ventricular mass in patients with type 2 diabetes mellitus and no overt cardiac disease. The DYDA study

Author

Cioffi G, Faggiano P, Lucci D, Di Lenarda A, Mureddu GF, Tarantini L, Verdecchia P, Comaschi M, Giorda CB, Velussi M, Chinali M, Latini R, Masson S, De Simone G, DYDAInvestigators Collaborators Comaschi M, Giorda C, de Simone G, Mureddu G, Maggioni AP, Vago T, Angeli F, Mazzotta G, Repaci S, Botta I, Casalnuovo G, Girfoglio D, Boemi M, Mocchegiani R, Corsi A, Ponzani P, Camerini A, Pinamonti B, Grosu A, Sforza A, Rambaldi R, Zarra E, Murtas MG, Montaldo C, Motta RM, Leonardi G, Marchese T, Brero ML, Magro G, Tanga M, Rotella CM, Lenuzza M, Baggiore CM, Leopardi A, Minneci C, Sulla A, De Micheli A, Papagna D, Maggi D, Spallarossa P, Aglialoro A, Magaja O, Sabbatini G, Cesareo F, Corda A, Pitzalis L, Masselli L, Midi P, PontiroliAE, Mauri C, Carletti F, Piatti P, Agricola E, Donà G, Frigato N, Manicardi V, Finardi L, Catellani E, Piazza A, Cozzolino D, Madau G, Scanu M, Reboldi G, Biagioli P, Arcangeli A, Marsocci A, Badia T, Dabizzi L, Trojani C, Amati S, Genovese S, Bragato RM, Vespasiani G, Galetta M, Floris F, Mastroianno S, Russo A, De Cosmo S, Sturaro R, Ubaldi S, Miselli V, Gambarati GP, Curci V, Mattioli R, Travaglini A, Mezzetti P, Bovelli D, Limone P, Mabritto B, Fonda M, Manca E, Pinamonti B., GENTILE, Sandro, Cioffi, G, Faggiano, P, Lucci, D, Di Lenarda, A, Mureddu, Gf, Tarantini, L, Verdecchia, P, Comaschi, M, Giorda, Cb, Velussi, M, Chinali, M, Latini, R, Masson, S, De Simone, G, DYDAInvestigators Collaborators Comaschi, M, Giorda, C, de Simone, G, Mureddu, G, Maggioni, Ap, Vago, T, Angeli, F, Mazzotta, G, Repaci, S, Botta, I, Casalnuovo, G, Girfoglio, D, Boemi, M, Mocchegiani, R, Corsi, A, Ponzani, P, Camerini, A, Pinamonti, B, Grosu, A, Sforza, A, Rambaldi, R, Zarra, E, Murtas, Mg, Montaldo, C, Motta, Rm, Leonardi, G, Marchese, T, Brero, Ml, Magro, G, Tanga, M, Rotella, Cm, Lenuzza, M, Baggiore, Cm, Leopardi, A, Minneci, C, Sulla, A, De Micheli, A, Papagna, D, Maggi, D, Spallarossa, P, Aglialoro, A, Magaja, O, Sabbatini, G, Cesareo, F, Corda, A, Pitzalis, L, Masselli, L, Midi, P, Pontiroliae, Mauri, C, Carletti, F, Piatti, P, Agricola, E, Donà, G, Frigato, N, Manicardi, V, Finardi, L, Catellani, E, Piazza, A, Gentile, Sandro, Cozzolino, D, Madau, G, Scanu, M, Reboldi, G, Biagioli, P, Arcangeli, A, Marsocci, A, Badia, T, Dabizzi, L, Trojani, C, Amati, S, Genovese, S, Bragato, Rm, Vespasiani, G, Galetta, M, Floris, F, Mastroianno, S, Russo, A, De Cosmo, S, Sturaro, R, Ubaldi, S, Miselli, V, Gambarati, Gp, Curci, V, Mattioli, R, Travaglini, A, Mezzetti, P, Bovelli, D, Limone, P, Mabritto, B, Fonda, M, Manca, E, and Pinamonti, B.

Abstract

An inappropriately high left ventricular mass (iLVM) may be detected in patients with diabetes mellitus. Several hemodynamic and nonhemodynamic factors stimulating LVM growth may actively operate in these patients. In this study, we assessed prevalence and factors associated with iLVM in patients with diabetes mellitus. METHODS: We analyzed baseline data from 708 patients (61 ± 7 years, 57% treated for hypertension) with type 2 diabetes mellitus without evidence of cardiac disease enrolled in the left ventricular dysfunction in diabetes study. iLVM was diagnosed by Doppler echocardiography as LVM more than 28% of the expected LVM predicted from height, sex and stroke work. RESULTS: iLVM was detected in 166 patients (23%), irrespective of concomitant hypertension. Patients with iLVM were more frequently women, had higher BMI and prevalence of metabolic syndrome, higher serum triglyceride levels and were treated more frequently with metformin and diuretics. In a multivariate model, female sex [odds ratio (OR) 1.502 (95% confidence interval (CI) 1.010-2.231), P = 0.04], higher serum triglyceride levels [OR 1.007 (95% CI 1.003-1.012), P

Published
2011

32. Predictors of early-stage left ventricular dysfunction in type 2 diabetes: results of DYDA study

Author

Giorda CB, Cioffi G, de Simone G, Di Lenarda A, Faggiano P, Latini R, Lucci D, Maggioni AP, Tarantini L, Velussi M, Verdecchia P, Comaschi M, DYDA I.n.v.e.s.t.i.g.a.t.o.r.s. Collaborators Comaschi M, Giorda C, Mureddu G, Masson S, Vago T, Angeli F, Mazzotta G, Repaci S, Botta I, Casalnuovo G, Chinali M, Girfoglio D, Boemi M, Mocchegiani R, Corsi A, Ponzani P, Camerini A, Pinamonti B, Grosu A, Sforza A, Rambaldi R, Zarra E, Murtas MG, Montaldo C, Motta RM, Leonardi G, Marchese T, Brero LM, Magro G, Tanga M, Bardini G, Lenuzza M, Baggiore CM, Leopardi A, Minneci C, Sulla A, De Micheli A, Papagna D, Maggi D, Spallarossa P, Aglialoro A, Magaja O, Sabbatini G, Cesareo F, Corda A, Pitzalis L, Masselli L, Midi P, Pontiroli AE, Mauri C, Carletti F, Piatti P, Agricola E, Dona G, Zanocco A, Manicardi V, Michelini M, Pattoneri P, Catellani E, Cozzolino D, Madau G, Scanu M, Reboldi G, Biagioli P, Arcangeli A, Marsocci A, Badia T, Dabizzi L, Trojani C, Amati S, Genovese S, Genovese L, Vespasiani G, Galetta M, Floris F, Mastroianno S, Russo A, Sturaro R, Ubaldi S, Miselli V, Gambarati GP, Curci V, Mattioli R, Travaglini A, Mezzetti P, Bovelli D, Limone P, Pizzuti A, Fonda M, Manca E, Pinamonti B., GENTILE, Sandro, Giorda, Cb, Cioffi, G, de Simone, G, Di Lenarda, A, Faggiano, P, Latini, R, Lucci, D, Maggioni, Ap, Tarantini, L, Velussi, M, Verdecchia, P, Comaschi, M, Collaborators Comaschi M, DYDA I. n. v. e. s. t. i. g. a. t. o. r. s., Giorda, C, Mureddu, G, Masson, S, Vago, T, Angeli, F, Mazzotta, G, Repaci, S, Botta, I, Casalnuovo, G, Chinali, M, Girfoglio, D, Boemi, M, Mocchegiani, R, Corsi, A, Ponzani, P, Camerini, A, Pinamonti, B, Grosu, A, Sforza, A, Rambaldi, R, Zarra, E, Murtas, Mg, Montaldo, C, Motta, Rm, Leonardi, G, Marchese, T, Brero, Lm, Magro, G, Tanga, M, Bardini, G, Lenuzza, M, Baggiore, Cm, Leopardi, A, Minneci, C, Sulla, A, De Micheli, A, Papagna, D, Maggi, D, Spallarossa, P, Aglialoro, A, Magaja, O, Sabbatini, G, Cesareo, F, Corda, A, Pitzalis, L, Masselli, L, Midi, P, Pontiroli, Ae, Mauri, C, Carletti, F, Piatti, P, Agricola, E, Dona, G, Zanocco, A, Manicardi, V, Michelini, M, Pattoneri, P, Catellani, E, Gentile, Sandro, Cozzolino, D, Madau, G, Scanu, M, Reboldi, G, Biagioli, P, Arcangeli, A, Marsocci, A, Badia, T, Dabizzi, L, Trojani, C, Amati, S, Genovese, S, Genovese, L, Vespasiani, G, Galetta, M, Floris, F, Mastroianno, S, Russo, A, Sturaro, R, Ubaldi, S, Miselli, V, Gambarati, Gp, Curci, V, Mattioli, R, Travaglini, A, Mezzetti, P, Bovelli, D, Limone, P, Pizzuti, A, Fonda, M, Manca, E, and Pinamonti, B.

Abstract

Better knowledge of prevalence and early-stage determinants of subclinical left ventricular dysfunction (LVD) in type 2 diabetes would be useful to design prevention strategies. The objective of the LVD in Diabetes (DYDA) study was to assess these points in patients without established cardiac disease. METHOD: Baseline clinical, ECG, laboratory and echocardiographic data from 751 patients (61 ± 7 years, 59% hypertensive) recruited by 37 Italian diabetes clinics were analysed. Clinical history, life habits, laboratory data (NT-proBNP, HsCRP, HbA1c, serum glucose, lipids and creatinine, liver enzymes, microalbuminuria, glomerular filtrate) and data on microvascular complications and drug therapy were collected. RESULTS: LVD was present in 59.9% of patients. Age (OR 1.05, 95% CI [1.02-1.07]), HbA1c (OR 1.27, 95% CI [1.09-1.49]), triglycerides (OR 1.003, 95% CI [1.001-1.006]), treatment with metformin (OR 1.62, 95% CI [1.09-2.40]) and doxazosine (OR 2.48, 95% CI [1.10-5.55]) were independent predictors of LVD. Glitazones were associated with reduced risk of diastolic dysfunction (OR 0.44, 95% CI [0.22-0.87]) whereas waist circumference and metformin were adversely associated with systolic dysfunction (OR 1.02, 95% CI [1.01-1.04] and 1.57, 95% CI [1.01-2.43], respectively). CONCLUSION: In asymptomatic and fairly controlled diabetic patients, age, worse HbA1c, traits of insulin resistance, such as visceral adiposity and triglycerides or treatment with metformin, and use of doxazosin indicate greater risk of LVD. Glitazones, at this stage, seem to be associated with better diastolic performance.

Published
2011

34. Poster Session Saturday 14 December - AM: 14/12/2013 08:30-12:30 * Location: Poster area

Author

Muraru, D., Addetia, K., Veronesi, F., Corsi, C., Mor-Avi, V., Yamat, M., Weinert, L., Lang, R., Badano, L., Faita, F., Di Lascio, N., Bruno, R., Bianchini, E., Ghiadoni, L., Sicari, R., Gemignani, V., Angelis, A., Ageli, K., Ioakimidis, N., Chrysohoou, C., Agelakas, A., Felekos, I., Vaina, S., Aznaourides, K., Vlachopoulos, C., Stefanadis, C., Nemes, A., Szolnoky, G., Gavaller, H., Gonczy, A., Kemeny, L., Forster, T., Ramalho, A., Placido, R., Marta, L., Menezes, M., Magalhaes, A., Cortez Dias, N., Martins, S., Almeida, A., Pinto, F., Nunes Diogo, A., Botezatu, C.-D., Enache, R., Popescu, B., Nastase, O., Coman, M., Ghiorghiu, I., Calin, A., Rosca, M., Beladan, C., Ginghina, C., Grapsa, J., Cabrita, I., Durighel, G., O'regan, D., Dawson, D., Nihoyannopoulos, P., Pellicori, P., Kallvikbacka-Bennett, A., Zhang, J., Lukaschuk, E., Joseph, A., Bourantas, C., Loh, H., Bragadeesh, T., Clark, A., Cleland, J., Lomax, S., Putzu, P., Diercx, R., Parsons, S., Dicken, B., Vered, Z., Adirevitz, L., Dragu, R., Blatt, A., Karev, E., Malca, Y., Roytvarf, A., Marek, D., Sovova, E., Berkova, M., Cihalik, C., Taborsky, M., Lindqvist, P., Tossavainen, E., Soderberg, S., Gonzales, M., Gustavsson, S., Henein, M., Sonne, C., Bott-Fluegel, L., Hauck, S., Lesevic, H., Hadamitzky, M., Wolf, P., Kolb, C., Bandera, F., Pellegrino, M., Generati, G., Donghi, V., Alfonzetti, E., Castelvecchio, S., Menicanti, L., Guazzi, M., Buchyte, S., Rinkuniene, D., Jurkevicius, R., Smarz, K., Zaborska, B., Jaxa-Chamiec, T., Maciejewski, P., Budaj, A., Santoro, A., Federico Alvino, F., Giovanni Antonelli, G., Roberta Molle, R., Matteo Bertini, M., Stefano Lunghetti, S., Sergio Mondillo, S., Henri, C., Magne, J., Dulgheru, R., Laaraibi, S., Voilliot, D., Kou, S., Pierard, L., Lancellotti, P., Szulik, M., Stabryla-Deska, J., Kalinowski, M., Sliwinska, A., Szymala, M., Lenarczyk, R., Kalarus, Z., Kukulski, T., Yiangou, K., Azina, C., Yiangou, A., Ioannides, M., Chimonides, S., Baysal, S., Pirat, B., Okyay, K., Bal, U., Muderrisoglu, H., Popovic, D., Ostojic, M., Petrovic, M., Vujisic-Tesic, B., Arandjelovic, A., Petrovic, I., Banovic, M., Popovic, B., Vukcevic, V., Damjanovic, S., Velasco Del Castillo, S., Onaindia Gandarias, J., Arana Achaga, X., Laraudogoitia Zaldumbide, E., Rodriguez Sanchez, I., Cacicedo De Bobadilla, A., Romero Pereiro, A., Aguirre Larracoechea, U., Salinas, T., Subinas, A., Elzbieciak, M., Wita, K., Grabka, M., Chmurawa, J., Doruchowska, A., Turski, M., Filipecki, A., Wybraniec, M., Mizia-Stec, K., Varho, V., Karjalainen, P., Lehtinen, T., Airaksinen, J., Ylitalo, A., Kiviniemi, T., Gargiulo, P., Galderisi, M., D' Amore, C., Lo Iudice, F., Savarese, G., Casaretti, L., Pellegrino, A., Fabiani, I., La Mura, L., Perrone Filardi, P., Kim, J. Y., Chung, W., Yu, J., Choi, Y., Park, C., Youn, H., Lee, M., Nagy, A., Manouras, A., Gunyeli, E., Gustafsson, U., Shahgaldi, K., Winter, R., Johnsson, J., Zagatina, A., Krylova, L., Zhuravskaya, N., Vareldzyan, Y., Tyurina, T., Clitsenko, O., Khalifa, E. A., Ashour, Z., Elnagar, W., Jung, I., Seo, H., Lee, S., Lim, D., Mizariene, V., Verseckaite, R., Janenaite, J., Jonkaitiene, R., Sanchez Espino, A., Bonaque Gonzalez, J., Merchan Ortega, G., Bolivar Herrera, N., Ikuta, I., Macancela Quinones, J., Gomez Recio, M., Silva Fazendas Adame, P. R., Caldeira, D., Stuart, B., Almeida, S., Cruz, I., Ferreira, A., Freire, G., Lopes, L., Cotrim, C., Pereira, H., Mediratta, A., Moss, J., Nayak, H., Al Amri, I., Debonnaire, P., Van Der Kley, F., Schalij, M., Bax, J., Ajmone Marsan, N., Delgado, V., Schmidt, F. P., Gniewosz, T., Jabs, A., Munzel, T., Jansen, T., Kaempfner, D., Hink, U., Von Bardeleben, R., Jose, J., George, O., Joseph, G., Adawi, S., Najjar, R., Ahronson, D., Shiran, A., Van Riel, A., Boerlage - Van Dijk, K., De Bruin - Bon, H., Araki, M., Meregalli, P., Koch, K., Vis, M., Mulder, B., Baan, J., Bouma, B., Marciniak, A., Elton, D., Glover, K., Campbell, I., Sharma, R., Batalha, S., Lourenco, C., Oliveira Da Silva, C., Caballero, L., Garcia-Lara, J., Gonzalez-Carrillo, J., Oliva, M., Saura, D., Garcia-Navarro, M., Espinosa, M., Pinar, E., Valdes, M., De La Morena, G., Barreiro Perez, M., Lopez Perez, M., Roy, D., Brecker, S., Venkateshvaran, A., Dash, P. K., Sola, S., Barooah, B., Govind, S. C., Brodin, L. A., Saura Espin, D., Caballero Jimenez, L., Gonzalez Carrillo, J., Oliva Sandoval, M., Lopez Ruiz, M., Garcia Navarro, M., Espinosa Garcia, M., Valdes Chavarri, M., De La Morena Valenzuela, G., Gatti, G., Dell'angela, L., Pinamonti, B., Benussi, B., Sinagra, G., Pappalardo, A., Hernandez, V., Saavedra, J., Gonzalez, A., Iglesias, P., Civantos, S., Guijarro, G., Monereo, S., Ikeda, M., Toh, N., Oe, H., Tanabe, Y., Watanabe, N., Ito, H., Ciampi, Q., Cortigiani, L., Pratali, L., Rigo, F., Villari, B., Picano, E., Yoon, J., Sohn, J., Kim, Y., Chang, H., Hong, G., Kim, T., Ha, J., Choi, B., Rim, S., Choi, E., Tibazarwa, K., Sliwa, K., Wonkam, A., Mayosi, B., Oryshchyn, N., Ivaniv, Y., Pavlyk, S., Lourenco, M. R., Azevedo, O., Moutinho, J., Nogueira, I., Fernandes, M., Pereira, V., Quelhas, I., Lourenco, A., Sunbul, M., Tigen, K., Karaahmet, T., Dundar, C., Ozben, B., Guler, A., Cincin, A., Bulut, M., Sari, I., Basaran, Y., Baydar, O., Kadriye Kilickesmez, K., Ugur Coskun, U., Polat Canbolat, P., Veysel Oktay, V., Umit Yasar Sinan, U., Okay Abaci, O., Cuneyt Kocas, C., Sinan Uner, S., Serdar Kucukoglu, S., Zaroui, A., Mourali, M., Ben Said, R., Asmi, M., Aloui, H., Kaabachi, N., Mechmeche, R., Saberniak, J., Hasselberg, N., Borgquist, R., Platonov, P., Holst, A., Edvardsen, T., Haugaa, K., Eran, A., Yueksel, D., Er, F., Gassanov, N., Rosenkranz, S., Baldus, S., Guedelhoefer, H., Faust, M., Caglayan, E., Matveeva, N., Nartsissova, G., Chernjavskij, A., Ippolito, R., De Palma, D., Muscariello, R., Santoro, C., Raia, R., Schiano-Lomoriello, V., Gargiulo, F., Lipari, P., Bonapace, S., Zenari, L., Valbusa, F., Rossi, A., Lanzoni, L., Canali, G., Molon, G., Campopiano, E., Barbieri, E., Ikonomidis, I., Varoudi, M., Papadavid, E., Theodoropoulos, K., Papadakis, I., Pavlidis, G., Triantafyllidi, H., Anastasiou - Nana, M., Rigopoulos, D., Lekakis, J., Ozen, G., Durmus, E., Kivrak, T., Atas, H., Direskeneli, H., Stevanovic, A., Dekleva, M., Trajic, S., Paunovic, N., Simic, A., Khan, S., Mushemi-Blake, S., Jouhra, F., Dennes, W., Monaghan, M., Melikian, N., Shah, A., Maceira Gonzalez, A. M., Lopez-Lereu, M., Monmeneu, J., Igual, B., Estornell, J., Boraita, A., Kosmala, W., Rojek, A., Bialy, D., Mysiak, A., Przewlocka-Kosmala, M., Popescu, I., Mancas, S., Mornos, C., Serbescu, I., Ionescu, G., Ionac, A., Gaudron, P., Niemann, M., Herrmann, S., Hu, K., Liu, D., Wojciech, K., Frantz, S., Bijnens, B., Ertl, G., Weidemann, F., Cosin-Sales, J., Ruvira, J., Diago, J., Aguilar, J., Cruz, C., Pinho, T., Madureira, A., Lebreiro, A., Dias, C., Ramos, I., Silva Cardoso, J., Julia Maciel, M., De Meester, P., Van De Bruaene, A., Herijgers, P., Voigt, J.-U., Budts, W., Franzoso, F., Voser, E., Wohlmut, C., Kellenberger, C., Valsangiacomo Buechel, E., Carrero, C., Benger, J., Parcerisa, M., Falconi, M., Oberti, P., Granja, M., Cagide, A., Del Pasqua, A., Secinaro, A., Antonelli, G., Iacomino, M., Toscano, A., Chinali, M., Esposito, C., Carotti, A., Pongiglione, G., Rinelli, G., Youssef Moustafa, A., Al Murayeh, M., Al Masswary, A., Al Sheikh, K., Moselhy, M., Dardir, M., Deising, J., Butz, T., Suermeci, G., Liebeton, J., Wennemann, R., Tzikas, S., Van Bracht, M., Prull, M., Trappe, H.-J., Martin Hidalgo, M., Delgado Ortega, M., Ruiz Ortiz, M., Mesa Rubio, D., Carrasco Avalos, F., Seoane Garcia, T., Pan Alvarez-Ossorio, M., Lopez Aguilera, J., Puentes Chiachio, M., Suarez De Lezo Cruz Conde, J., Petrovic, M. T., Giga, V., Stepanovic, J., Tesic, M., Jovanovic, I., Djordjevic-Dikic, A., Piatkowski, R., Kochanowski, J., Scislo, P., Opolski, G., Vareldzhyan, Y., Bombardini, T., Gherardi, S., Leone, O., Michelotto, E., Ciccarone, A., Tarantino, N., Ostuni, V., Rubino, M., Genco, W., Santoro, G., Carretta, D., Romito, R., Colonna, P., Cameli, M., Lunghetti, S., Lisi, M., Curci, V., Cameli, P., Focardi, M., Favilli, R., Mondillo, S., Hoffmann, R., Barletta, G., Von Bardeleben, S., Kasprzak, J., Greis, C., Vanoverschelde, J., Becher, H., Machida, T., Izumo, M., Suzuki, K., Kaimijima, R., Mizukoshi, K., Manabe-Uematsu, M., Takai, M., Harada, T., Akashi, Y., Martin Garcia, A., Arribas-Jimenez, A., Cruz-Gonzalez, I., Nieto, F., Iscar, A., Merchan, S., Martin-Luengo, C., Brecht, A., Theres, L., Spethmann, S., Dreger, H., Baumann, G., Knebel, F., Jasaityte, R., Heyde, B., Rademakers, F., Claus, P., D'hooge, J., Lervik Nilsen, L. C., Lund, J., Brekke, B., Stoylen, A., Giraldeau, G., Duchateau, N., Gabrielli, L., Penela, D., Evertz, R., Mont, L., Brugada, J., Berruezo, A., Sitges, M., Kordybach, M., Kowalski, M., Hoffman, P., Pilichowska, E., Baran, J., Kulakowski, P., Wahi, S., Vollbon, W., Leano, R., Thomas, A., Bricknell, K., Holland, D., Napier, S., Stanton, T., Teferici, D., Qirko, S., Petrela, E., Dibra, A., Bajraktari, G., Bara, P., Sanchis Ruiz, L., Andrea, R., Falces, C., Perez-Villa, F., Sulemane, S., Panoulas, V., Bratsas, A., Tam, F., Abduch, M., Alencar, A., Coracin, F., Barban, A., Saboya, R., Dulley, F., Mathias, W., Vieira, M., Buccheri, S., Mangiafico, S., Arcidiacono, A., Bottari, V., Leggio, S., Tamburino, C., Monte, I. P., Spitzer, E., Beitzke, D., Kaneider, A., Pavo, N., Gottsauner-Wolf, M., Wolf, F., Loewe, C., Mushtaq, S., Andreini, D., Pontone, G., Bertella, E., Conte, E., Baggiano, A., Annoni, A., Cortinovis, S., Fiorentini, C., Pepi, M., Gustafsson, M., Alehagen, U., Dahlstrom, U., Johansson, P., Faden, G., Faggiano, P., Albertini, L., Reverberi, C., Gaibazzi, N., Taylor, R. J., Moody, W., Umar, F., Edwards, N., Townend, J., Steeds, R., Leyva, F., Mihaila, S., Piasentini, E., Peluso, D., Casablanca, S., Naso, P., Puma, L., Iliceto, S., Vinereanu, D., Ciciarello, F. L., Agati, L., Cimino, S., De Luca, L., Petronilli, V., Fedele, F., and Tsverava, M.

Subjects
medicine.medical_specialty, Bundle branch block, business.industry, Left bundle branch block, Speckle tracking echocardiography, General Medicine, 030204 cardiovascular system & hematology, medicine.disease, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Radial function, Ventricle, Internal medicine, Cardiology, medicine, Radiology, Nuclear Medicine and imaging, In patient, Cardiology and Cardiovascular Medicine, business
Published
2013
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35. Left atrial function measured by cardiac magnetic resonance in patients with heart failure: clinical associations and prognostic value

Author

Muraru, D., Addetia, K., Veronesi, F., Corsi, C., Mor-Avi, V., Yamat, M., Weinert, L., Lang, R., Badano, L., Faita, F., Di Lascio, N., Bruno, R., Bianchini, E., Ghiadoni, L., Sicari, R., Gemignani, V., Angelis, A., Ageli, K., Ioakimidis, N., Chrysohoou, C., Agelakas, A., Felekos, I., Vaina, S., Aznaourides, K., Vlachopoulos, C., Stefanadis, C., Nemes, A., Szolnoky, G., Gavaller, H., Gonczy, A., Kemeny, L., Forster, T., Ramalho, A., Placido, R., Marta, L., Menezes, M., Magalhaes, A., Cortez Dias, N., Martins, S., Almeida, A., Pinto, F., Nunes Diogo, A., Botezatu, C.-D., Enache, R., Popescu, B., Nastase, O., Coman, M., Ghiorghiu, I., Calin, A., Rosca, M., Beladan, C., Ginghina, C., Grapsa, J., Cabrita, I., Durighel, G., O'regan, D., Dawson, D., Nihoyannopoulos, P., Pellicori, P., Kallvikbacka-Bennett, A., Zhang, J., Lukaschuk, E., Joseph, A., Bourantas, C., Loh, H., Bragadeesh, T., Clark, A., Cleland, J., Lomax, S., Putzu, P., Diercx, R., Parsons, S., Dicken, B., Vered, Z., Adirevitz, L., Dragu, R., Blatt, A., Karev, E., Malca, Y., Roytvarf, A., Marek, D., Sovova, E., Berkova, M., Cihalik, C., Taborsky, M., Lindqvist, P., Tossavainen, E., Soderberg, S., Gonzales, M., Gustavsson, S., Henein, M., Sonne, C., Bott-Fluegel, L., Hauck, S., Lesevic, H., Hadamitzky, M., Wolf, P., Kolb, C., Bandera, F., Pellegrino, M., Generati, G., Donghi, V., Alfonzetti, E., Castelvecchio, S., Menicanti, L., Guazzi, M., Buchyte, S., Rinkuniene, D., Jurkevicius, R., Smarz, K., Zaborska, B., Jaxa-Chamiec, T., Maciejewski, P., Budaj, A., Santoro, A., Federico Alvino, F., Giovanni Antonelli, G., Roberta Molle, R., Matteo Bertini, M., Stefano Lunghetti, S., Sergio Mondillo, S., Henri, C., Magne, J., Dulgheru, R., Laaraibi, S., Voilliot, D., Kou, S., Pierard, L., Lancellotti, P., Szulik, M., Stabryla-Deska, J., Kalinowski, M., Sliwinska, A., Szymala, M., Lenarczyk, R., Kalarus, Z., Kukulski, T., Yiangou, K., Azina, C., Yiangou, A., Ioannides, M., Chimonides, S., Baysal, S., Pirat, B., Okyay, K., Bal, U., Muderrisoglu, H., Popovic, D., Ostojic, M., Petrovic, M., Vujisic-Tesic, B., Arandjelovic, A., Petrovic, I., Banovic, M., Popovic, B., Vukcevic, V., Damjanovic, S., Velasco Del Castillo, S., Onaindia Gandarias, J., Arana Achaga, X., Laraudogoitia Zaldumbide, E., Rodriguez Sanchez, I., Cacicedo De Bobadilla, A., Romero Pereiro, A., Aguirre Larracoechea, U., Salinas, T., Subinas, A., Elzbieciak, M., Wita, K., Grabka, M., Chmurawa, J., Doruchowska, A., Turski, M., Filipecki, A., Wybraniec, M., Mizia-Stec, K., Varho, V., Karjalainen, P., Lehtinen, T., Airaksinen, J., Ylitalo, A., Kiviniemi, T., Gargiulo, P., Galderisi, M., D' Amore, C., Lo Iudice, F., Savarese, G., Casaretti, L., Pellegrino, A., Fabiani, I., La Mura, L., Perrone Filardi, P., Kim, J. Y., Chung, W., Yu, J., Choi, Y., Park, C., Youn, H., Lee, M., Nagy, A., Manouras, A., Gunyeli, E., Gustafsson, U., Shahgaldi, K., Winter, R., Johnsson, J., Zagatina, A., Krylova, L., Zhuravskaya, N., Vareldzyan, Y., Tyurina, T., Clitsenko, O., Khalifa, E. A., Ashour, Z., Elnagar, W., Jung, I., Seo, H., Lee, S., Lim, D., Mizariene, V., Verseckaite, R., Janenaite, J., Jonkaitiene, R., Sanchez Espino, A., Bonaque Gonzalez, J., Merchan Ortega, G., Bolivar Herrera, N., Ikuta, I., Macancela Quinones, J., Gomez Recio, M., Silva Fazendas Adame, P. R., Caldeira, D., Stuart, B., Almeida, S., Cruz, I., Ferreira, A., Freire, G., Lopes, L., Cotrim, C., Pereira, H., Mediratta, A., Moss, J., Nayak, H., Al Amri, I., Debonnaire, P., Van Der Kley, F., Schalij, M., Bax, J., Ajmone Marsan, N., Delgado, V., Schmidt, F. P., Gniewosz, T., Jabs, A., Munzel, T., Jansen, T., Kaempfner, D., Hink, U., Von Bardeleben, R., Jose, J., George, O., Joseph, G., Adawi, S., Najjar, R., Ahronson, D., Shiran, A., Van Riel, A., Boerlage - Van Dijk, K., De Bruin - Bon, H., Araki, M., Meregalli, P., Koch, K., Vis, M., Mulder, B., Baan, J., Bouma, B., Marciniak, A., Elton, D., Glover, K., Campbell, I., Sharma, R., Batalha, S., Lourenco, C., Oliveira Da Silva, C., Caballero, L., Garcia-Lara, J., Gonzalez-Carrillo, J., Oliva, M., Saura, D., Garcia-Navarro, M., Espinosa, M., Pinar, E., Valdes, M., De La Morena, G., Barreiro Perez, M., Lopez Perez, M., Roy, D., Brecker, S., Venkateshvaran, A., Dash, P. K., Sola, S., Barooah, B., Govind, S. C., Brodin, L. A., Saura Espin, D., Caballero Jimenez, L., Gonzalez Carrillo, J., Oliva Sandoval, M., Lopez Ruiz, M., Garcia Navarro, M., Espinosa Garcia, M., Valdes Chavarri, M., De La Morena Valenzuela, G., Gatti, G., Dell'angela, L., Pinamonti, B., Benussi, B., Sinagra, G., Pappalardo, A., Hernandez, V., Saavedra, J., Gonzalez, A., Iglesias, P., Civantos, S., Guijarro, G., Monereo, S., Ikeda, M., Toh, N., Oe, H., Tanabe, Y., Watanabe, N., Ito, H., Ciampi, Q., Cortigiani, L., Pratali, L., Rigo, F., Villari, B., Picano, E., Yoon, J., Sohn, J., Kim, Y., Chang, H., Hong, G., Kim, T., Ha, J., Choi, B., Rim, S., Choi, E., Tibazarwa, K., Sliwa, K., Wonkam, A., Mayosi, B., Oryshchyn, N., Ivaniv, Y., Pavlyk, S., Lourenco, M. R., Azevedo, O., Moutinho, J., Nogueira, I., Fernandes, M., Pereira, V., Quelhas, I., Lourenco, A., Sunbul, M., Tigen, K., Karaahmet, T., Dundar, C., Ozben, B., Guler, A., Cincin, A., Bulut, M., Sari, I., Basaran, Y., Baydar, O., Kadriye Kilickesmez, K., Ugur Coskun, U., Polat Canbolat, P., Veysel Oktay, V., Umit Yasar Sinan, U., Okay Abaci, O., Cuneyt Kocas, C., Sinan Uner, S., Serdar Kucukoglu, S., Zaroui, A., Mourali, M., Ben Said, R., Asmi, M., Aloui, H., Kaabachi, N., Mechmeche, R., Saberniak, J., Hasselberg, N., Borgquist, R., Platonov, P., Holst, A., Edvardsen, T., Haugaa, K., Eran, A., Yueksel, D., Er, F., Gassanov, N., Rosenkranz, S., Baldus, S., Guedelhoefer, H., Faust, M., Caglayan, E., Matveeva, N., Nartsissova, G., Chernjavskij, A., Ippolito, R., De Palma, D., Muscariello, R., Santoro, C., Raia, R., Schiano-Lomoriello, V., Gargiulo, F., Lipari, P., Bonapace, S., Zenari, L., Valbusa, F., Rossi, A., Lanzoni, L., Canali, G., Molon, G., Campopiano, E., Barbieri, E., Ikonomidis, I., Varoudi, M., Papadavid, E., Theodoropoulos, K., Papadakis, I., Pavlidis, G., Triantafyllidi, H., Anastasiou - Nana, M., Rigopoulos, D., Lekakis, J., Ozen, G., Durmus, E., Kivrak, T., Atas, H., Direskeneli, H., Stevanovic, A., Dekleva, M., Trajic, S., Paunovic, N., Simic, A., Khan, S., Mushemi-Blake, S., Jouhra, F., Dennes, W., Monaghan, M., Melikian, N., Shah, A., Maceira Gonzalez, A. M., Lopez-Lereu, M., Monmeneu, J., Igual, B., Estornell, J., Boraita, A., Kosmala, W., Rojek, A., Bialy, D., Mysiak, A., Przewlocka-Kosmala, M., Popescu, I., Mancas, S., Mornos, C., Serbescu, I., Ionescu, G., Ionac, A., Gaudron, P., Niemann, M., Herrmann, S., Hu, K., Liu, D., Wojciech, K., Frantz, S., Bijnens, B., Ertl, G., Weidemann, F., Cosin-Sales, J., Ruvira, J., Diago, J., Aguilar, J., Cruz, C., Pinho, T., Madureira, A., Lebreiro, A., Dias, C., Ramos, I., Silva Cardoso, J., Julia Maciel, M., De Meester, P., Van De Bruaene, A., Herijgers, P., Voigt, J.-U., Budts, W., Franzoso, F., Voser, E., Wohlmut, C., Kellenberger, C., Valsangiacomo Buechel, E., Carrero, C., Benger, J., Parcerisa, M., Falconi, M., Oberti, P., Granja, M., Cagide, A., Del Pasqua, A., Secinaro, A., Antonelli, G., Iacomino, M., Toscano, A., Chinali, M., Esposito, C., Carotti, A., Pongiglione, G., Rinelli, G., Youssef Moustafa, A., Al Murayeh, M., Al Masswary, A., Al Sheikh, K., Moselhy, M., Dardir, M., Deising, J., Butz, T., Suermeci, G., Liebeton, J., Wennemann, R., Tzikas, S., Van Bracht, M., Prull, M., Trappe, H.-J., Martin Hidalgo, M., Delgado Ortega, M., Ruiz Ortiz, M., Mesa Rubio, D., Carrasco Avalos, F., Seoane Garcia, T., Pan Alvarez-Ossorio, M., Lopez Aguilera, J., Puentes Chiachio, M., Suarez De Lezo Cruz Conde, J., Petrovic, M. T., Giga, V., Stepanovic, J., Tesic, M., Jovanovic, I., Djordjevic-Dikic, A., Piatkowski, R., Kochanowski, J., Scislo, P., Opolski, G., Vareldzhyan, Y., Bombardini, T., Gherardi, S., Leone, O., Michelotto, E., Ciccarone, A., Tarantino, N., Ostuni, V., Rubino, M., Genco, W., Santoro, G., Carretta, D., Romito, R., Colonna, P., Cameli, M., Lunghetti, S., Lisi, M., Curci, V., Cameli, P., Focardi, M., Favilli, R., Mondillo, S., Hoffmann, R., Barletta, G., Von Bardeleben, S., Kasprzak, J., Greis, C., Vanoverschelde, J., Becher, H., Machida, T., Izumo, M., Suzuki, K., Kaimijima, R., Mizukoshi, K., Manabe-Uematsu, M., Takai, M., Harada, T., Akashi, Y., Martin Garcia, A., Arribas-Jimenez, A., Cruz-Gonzalez, I., Nieto, F., Iscar, A., Merchan, S., Martin-Luengo, C., Brecht, A., Theres, L., Spethmann, S., Dreger, H., Baumann, G., Knebel, F., Jasaityte, R., Heyde, B., Rademakers, F., Claus, P., D'hooge, J., Lervik Nilsen, L. C., Lund, J., Brekke, B., Stoylen, A., Giraldeau, G., Duchateau, N., Gabrielli, L., Penela, D., Evertz, R., Mont, L., Brugada, J., Berruezo, A., Sitges, M., Kordybach, M., Kowalski, M., Hoffman, P., Pilichowska, E., Baran, J., Kulakowski, P., Wahi, S., Vollbon, W., Leano, R., Thomas, A., Bricknell, K., Holland, D., Napier, S., Stanton, T., Teferici, D., Qirko, S., Petrela, E., Dibra, A., Bajraktari, G., Bara, P., Sanchis Ruiz, L., Andrea, R., Falces, C., Perez-Villa, F., Sulemane, S., Panoulas, V., Bratsas, A., Tam, F., Abduch, M., Alencar, A., Coracin, F., Barban, A., Saboya, R., Dulley, F., Mathias, W., Vieira, M., Buccheri, S., Mangiafico, S., Arcidiacono, A., Bottari, V., Leggio, S., Tamburino, C., Monte, I. P., Spitzer, E., Beitzke, D., Kaneider, A., Pavo, N., Gottsauner-Wolf, M., Wolf, F., Loewe, C., Mushtaq, S., Andreini, D., Pontone, G., Bertella, E., Conte, E., Baggiano, A., Annoni, A., Cortinovis, S., Fiorentini, C., Pepi, M., Gustafsson, M., Alehagen, U., Dahlstrom, U., Johansson, P., Faden, G., Faggiano, P., Albertini, L., Reverberi, C., Gaibazzi, N., Taylor, R. J., Moody, W., Umar, F., Edwards, N., Townend, J., Steeds, R., Leyva, F., Mihaila, S., Piasentini, E., Peluso, D., Casablanca, S., Naso, P., Puma, L., Iliceto, S., Vinereanu, D., Ciciarello, F. L., Agati, L., Cimino, S., De Luca, L., Petronilli, V., Fedele, F., and Tsverava, M.

Published
2013
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36. Long-term prognostic impact of therapeutic strategies in patients with idiopathic dilated cardiomyopathy: changing mortality over the last 30 years

Author

Merlo, M, Pivetta, A, Pinamonti, B, Stolfo, D, Zecchin, M, Barbati, Giulia, Di Lenarda, A, Sinagra, Gianfranco, Merlo, M, Pivetta, A, Pinamonti, B, Stolfo, D, Zecchin, M, Barbati, Giulia, Di Lenarda, A, and Sinagra, Gianfranco

Subjects
Adult, Cardiomyopathy, Dilated, Male, Digoxin, Cardiotonic Agents, Adrenergic beta-Antagonists, Idiopathic Dilated Cardiomyopathy, Angiotensin-Converting Enzyme Inhibitors, Middle Aged, Prognosis, Defibrillators, Implantable, Cardiac Resynchronization Therapy, Survival Rate, Angiotensin Receptor Antagonists, Treatment Outcome, Risk Factors, Humans, Female, Mortality, Diuretics, Mineralocorticoid Receptor Antagonists
Abstract

ACE-inhibitors, β-blockers, implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy (CRT) improved prognosis of heart failure. We sought to analyse the long-term prognostic impact of evidence-based integrated therapeutic strategies in patients with idiopathic dilated cardiomyopathy (IDCM).From 1978 to 2007, 853 IDCM patients (45 ± 15 years, 72\% males) were enrolled and classified as follows: Group 1, 110 patients (12.8\%) enrolled during 1978-1987; Group 2, 376 patients (44.1\%) enrolled during 1988-1997; Group 3, 367 patients (43.1\%) enrolled during 1998-2007. ACE-inhibitors/angiotensin receptor blockers were administered in 34\%, 93\%, and 93\% (P

Published
2014

38. P981Lvot area measurement using gated ct data reclassifies aortic stenosis severity as graded by echocardiographyP982Paradoxical low-flow low-gradient aortic stenosis: an intermediate state between moderate and severe aortic stenosis?P983Can rheumatic significant mitral stenosis be a cause of paradoxical low gradient, low flow, in patients with severe aortic stenosis? an echocardiographic and outcome studyP984Clinical and hemodynamic comparison of isolated versus combined aortic and mitral stenosisP985Echocardiographic end-diastolic velocity in the proximal descending aorta should be interpreted with caution when the ascending aorta is dilated: insights from cardiovascular magnetic resonanceP987Prevalence of atrial mitral regurgitation in patients with severe mitral regurgitationP988Role of 2D/3D echocardiography in the risk stratification of endocardial lead-related tricuspid regurgitation: a single-centre study among?241 patientsP989When TEE is needed in patients with staphylococcus aureus bacteremia for the assessment of risk profile of infective endocarditis?P990Appropriateness criteria to echocardiograms for suspected infective endocarditis: experience of a tertiary referral centerP991Independent predictors of outcome in infective endocarditisP992The role of transesophageal cardiography in clinical course and prognosis of complicated infective endocarditis in critically ill patients: our 15 years experienceP993Left bundle branch block atypical pattern as a prognostic determinant in patients taken to TAVIP994Efficacy of long-term ivabradine therapy in severe systolic chronic heart failure patients with and without type 2 diabetes mellitusP995Relations between left ventricular reverse remodeling and serum markers of extracellular matrix fibrosis in dilated cardiomyopathyP996The healthy left ventricle accommodates an increasing vortex formation time for volume transfer in diastolic filling :Implications for heart failureP997Evolutionary changes of pulmonary artery pressure after left ventricular assist device implantP998Functional correlates and prognostic value of coronary flow velocity reserve by vasodilator stress echocardiography in hypertrophic cardiomyopathyP999Quantification of myocardial performance in patients with non-obstructive versus latent-obstructive hypertrophic cardiomyopathyP1000Lifelong arrhythmic risk stratification in arrhythmogenic right ventricular cardiomyopathy: distribution of events and impact of periodical reassessmentP1001Impact of fibrosis visualized by CMR in vectorcardiogram recordings of patients with suspected arrhythmogenic cardiomyopathyP1002Determinants of the beneficial effect of aldosterone antagonism on exercise capacity in heart failure with reduced ejection fractionP1003Myocardial strain values in patients with acute myocarditis and preserved ejection fraction. A magnetic resonance feature tracking studyP1004Detection of subclinical left ventricular dysfunction by speckle tracking echocardiography in patients with myocarditis without prominent wall motion abnormalitiesP1005Aborted sudden cardiac death patients aged <50 years show only mild alterations on cardiac magnetic resonance imagingP1006Relationships between subepicardial and subendocardial longitudinal strain with late gadolinium enhancement in uncomplicated hypertensive patients

Author

Moderato, L., primary, Di Nora, C., primary, Soufiani, A., primary, Bech-Hanssen, O., primary, Johnson, K., primary, Hamadanchi, A., primary, Longobardo, L., primary, Casadei, F., primary, Ilhao Moreira, R., primary, Ahmad, F., primary, Parra Laca, B., primary, Tumasyan, LR., primary, Wisniowska-Smialek, S., primary, King, GJ., primary, Di Ruocco, MV., primary, Ciampi, Q., primary, Wang, J., primary, Cappelletto, C., primary, Igual Munoz, B., primary, Kosmala, W., primary, Almeida, A M G, primary, Kostakou, P., primary, Zaremba, T., primary, Contaldi, C., primary, Palumbo, A., additional, Coli, S., additional, Orlandini, D., additional, Russo, G., additional, Gaibazzi, N., additional, Poli, S., additional, Vriz, O., additional, Zito, C., additional, Carerj, S., additional, Pavan, D., additional, Antonini-Canterin, F., additional, Ougnou, H., additional, Elhattab, FZ., additional, Bendagha, N., additional, Tribak, M., additional, Lahchab, FZ., additional, Mahfoudi, L., additional, Fadel, B., additional, Moughil, S., additional, Mohty, D., additional, El Hattab, FZ., additional, Aboyans, V., additional, Polte, CL., additional, Svensson, F., additional, Johnsson, ÅA, additional, Lagerstrand, KM., additional, Gao, SA., additional, Abdel-Rahman, ST., additional, Dobson, L., additional, Gatenby, K., additional, Kidambi, A., additional, Schlosshan, D., additional, Moradi, B., additional, Asadi, Y., additional, Poerner, TC., additional, Doenst, T., additional, Schulze, PC., additional, Goebel, B., additional, Trio, O., additional, Cusma'-Piccione, M., additional, Di Bella, G., additional, Khandheria, BK., additional, De Chiara, B., additional, Spano', F., additional, Bokor, D., additional, Quattrocchi, S., additional, Varrenti, M., additional, Vigano', E., additional, Rinaldi, I., additional, Giannattasio, C., additional, Moreo, A., additional, Coutinho Cruz, M., additional, Moura Branco, L., additional, Galrinho, A., additional, Coutinho Miranda, L., additional, Viveiros Monteiro, A., additional, Aguiar Rosa, S., additional, Rodrigues, I., additional, Fragata, J., additional, Cruz Ferreira, R., additional, Cox, S., additional, Chan, ST., additional, Abdul Rahman, E., additional, Zainal Abidin, I., additional, Sadiq, MA., additional, Islas, F., additional, De Agustin, A., additional, Nombela, L., additional, Marcos-Alberca, P., additional, Macaya, C., additional, Perez De Isla, L., additional, Olmos, C., additional, Adamyan, KG., additional, Rubis, P., additional, Khachatryan, L., additional, Karabinowska, A., additional, Faltyn, P., additional, Dziewiecka, E., additional, Biernacka-Fialkowska, B., additional, Hlawaty, M., additional, Kostkiewicz, M., additional, Podolec, P., additional, Coen, K., additional, Serseniuc, M., additional, Nolan, PG., additional, Clarke, JG., additional, Temporelli, PL., additional, Pistono, M., additional, Imparato, A., additional, Eleuteri, E., additional, Giannuzzi, P., additional, Cortigiani, L., additional, Tesic, M., additional, Beleslin, B., additional, Rigo, F., additional, Djorkievic-Dikic, A., additional, Picano, E., additional, Zuo, L., additional, Ta, SJ., additional, Kang, N., additional, Zhou, MY., additional, Guo, RQ., additional, Liu, L., additional, Stolfo, D., additional, De Luca, A., additional, Pinamonti, B., additional, Barbati, G., additional, Gobbo, G., additional, Pivetta, A., additional, Brun, F., additional, Merlo, M., additional, Sinagra, G., additional, Sanz, JS., additional, Molina-Aguilar, PMA, additional, Castells Ramon, FCR, additional, Giner Blasco, JGB, additional, Santiago Jimenez, SG., additional, Maceira-Gonzalez, AMG, additional, Monserrat Reina, AMR, additional, Tuset Sanchez, LTS, additional, Zorio-Grima, EZG, additional, Sacharczuk, W., additional, Kotwica, T., additional, Dankowski, R., additional, Przewlocka-Kosmala, M., additional, Kobusiak-Prokopowicz, M., additional, Mysiak, A., additional, Szyszka, A., additional, Menezes, MN., additional, Lima Silva, G., additional, Guimaraes, T., additional, Francisco, AR., additional, Placido, R., additional, David, C., additional, Pinto, FJ., additional, Kouris, N., additional, Trifou, E., additional, Kostopoulos, V., additional, Hatzigiannis, P., additional, Olympios, CD., additional, Broendberg, AK., additional, Jensen, HK., additional, Kim, WY., additional, Imbriaco, M., additional, Alcidi, G., additional, Ponsiglione, A., additional, Santoro, C., additional, Puglia, M., additional, Barbuto, L., additional, Cuocolo, A., additional, Trimarco, B., additional, and Galderisi, M., additional

Published
2016
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39. Moderated Posters: A little bit of everythingP1190What causes mitral annulus dilatation-A three dimensional studyP1191Impact of interventional edge-to-edge repair with the MitraClip system on mitral valve geometry: Long-term results from a prospective single centre studyP1192Real live applications of three-dimensional echocardiographic quantification of the left atrial volumes using an automated adaptive analytics algorithmP1193Quantitative ultrasound evaluation of the changes on tissue characteristics of carotid plaques by lipid lowering therapyP1194Effort heart rate increase is an independent predictor of longitudinal function reserve in the trained heart: a stress echocardiography studyP1195Incremental value of strain imaging in classification of heart failure with normal ejection fractionP1196Multimodality work-up of young stroke patients is beneficialP1197Prognostic significance of the hemodynamic non-invasive assessment in patients with dilated cardiomyopathy

Author

Boileve, V, primary, Schueler, R., primary, Hinojar, R., primary, Bando, M., primary, Lo Iudice, F., primary, Andersen, OS., primary, Nielsen, KM., primary, Merlo, M., primary, Dreyfus, J, additional, Attias, D., additional, Codogno, I., additional, Brochet, E., additional, Vahanian, A., additional, Messika-Zeitoun, D., additional, Kaplan, S., additional, Oeztuerk, C., additional, Weber, M., additional, Sinning, JM., additional, Welt, A., additional, Werner, N., additional, Nickenig, G., additional, Hammerstingl, C., additional, Fernandez-Golfin, C., additional, Gonzalez-Gomez, A., additional, Garcia Martin, A., additional, Casas, E., additional, Del Val, D., additional, Pardo, A., additional, Mejias, A., additional, Moya, JL., additional, Barrios, V., additional, Jimenez Nacher, JJ., additional, Zamorano, JL., additional, Yamada, H., additional, Amano, R., additional, Tamai, R., additional, Torii, Y., additional, Nishio, S., additional, Seno, Y., additional, Kusunose, K., additional, Sata, M., additional, Santoro, C., additional, Buonauro, A., additional, Ferrone, M., additional, Esposito, R., additional, Trimarco, B., additional, Petitto, M., additional, Galderisi, M., additional, Gude, E., additional, Andreassen, AK., additional, Broch, K., additional, Skulstad, H., additional, Smiseth, OA., additional, Remme, EW., additional, Damgaard, DW., additional, Jensen, JM., additional, Kraglund, KL., additional, Kim, WY., additional, Stolfo, D., additional, Gobbo, M., additional, Gabassi, G., additional, Barbati, G., additional, De Luca, A., additional, Korcova, R., additional, Secoli, G., additional, Pinamonti, B., additional, and Sinagra, G., additional

Published
2016
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41. Cardiomiopatia dilatativa: una, nessuna, centomila

Author

Brun F., Pinamonti B., Pyxaras S., Merlo M., Rakar S., Perkan A., Camerini F., SABBADINI, GASTONE, BUSSANI, ROSSANA, SINAGRA, GIANFRANCO, Prati, Brun, F., Pinamonti, B., Pyxaras, S., Merlo, M., Sabbadini, Gastone, Rakar, S., Perkan, A., Bussani, Rossana, Camerini, F., and Sinagra, Gianfranco

Subjects
Cardiomiopatia dilatativa
Abstract

Cardiomiopatia dilatativa

Published
2010

42. L’irruzione della genetica nell’eziologia delle malattie del miocardio: cosa il cardiologo deve sapere

Author

BRUN F, LARDIERI G, PERKAN A, MERLO M, MORETTI M, PINAMONTI B, ZECCHIN M, MASSA L, LONGARO F, SILVESTRI, FURIO, BUSSANI, ROSSANA, MESTRONI L, SINAGRA, GIANFRANCO, Prati, Brun, F, Lardieri, G, Perkan, A, Merlo, M, Moretti, M, Pinamonti, B, Zecchin, M, Massa, L, Longaro, F, Silvestri, Furio, Bussani, Rossana, Mestroni, L, and Sinagra, Gianfranco

Subjects
cardiomiopatie, Genetica
Published
2009

43. Asymmetric ring annuloplasty for ischemic mitral regurgitation: early and mid-term outcomes

Author

Gatti, G., Angela, L., Pinamonti, B., Gon, L., Benussi, B., GIANFRANCO SINAGRA, Pappalardo, A., Gatti, Giuseppe, Dell'Angela, Luca, Pinamonti, Bruno, Gon, Livio, Benussi, Bernardo, Sinagra, Gianfranco, and Pappalardo, Aniello

Subjects
Male, Mitral Valve Annuloplasty, Time Factors, Myocardial Ischemia, Kaplan-Meier Estimate, Severity of Illness Index, Disease-Free Survival, Postoperative Complications, Humans, annuloplasty, mitral regurgitation, outcome, Hospital Mortality, Vascular Diseases, Aged, Retrospective Studies, Mitral Valve Insufficiency, Middle Aged, Treatment Outcome, Italy, Echocardiography, Mitral Valve, Female, Kidney Diseases, Risk Adjustment, Follow-Up Studies
Abstract

The Carpentier-McCarthy-Adams IMR ETlogix annuloplasty ring was specifically designed to treat ischemic mitral regurgitation (IMR) associated with asymmetric mitral annular dilation and leaflet tethering. The study aim was to review, retrospectively, the results of mitral annuloplasty with this asymmetric ring in a representative number of patients.Between January 2005 and July 2012, the IMR ETlogix ring was implanted in 190 consecutive patients (mean age 69.5 +/- 7.6 years) with gradeor =2+ IMR (graded from 0 to 3+). Preoperatively, 37 patients (19.5%) were in NYHA class IV, and 73 (38.4%) suffered from unstable angina. The operative risk according to the European System for Cardiac Operative Risk Evaluation II was 15.6 +/- 14.5%. Using two- dimensional echocardiography, postoperative changes in mitral annular diameter (MAD) and tenting height (TH) of the mitral valve in four-chamber, two-chamber and long-axis views, were assessed at mid-systole.Thirty-eight patients (20.0%) received one or more concomitant major cardiac surgical procedure(s) other than, or in addition to, coronary artery bypass grafting or tricuspid valve annuloplasty. Nineteen (10.0%) hospital deaths occurred, and one patient underwent immediate reoperation for residual MR. During the follow up (mean 4.8 +/- 2.1 years) there were 26 cardiac deaths, 14 non-cardiac deaths, and three mitral valve replacements. The seven-year actuarial survival, freedom from gradeor =2+ MR and reoperation were 62.0%, 93.1% and 97.6%, respectively. Renal impairment (p = 0.012) and extracardiac arteriopathy (p = 0.047) were predictors of death; bilateral internal thoracic artery grafting was a protective factor (p = 0.033). Heart failure symptoms were improved (p0.01). Left ventricular reverse remodeling was achieved in 50.6% of patients. The MAD and TH were each decreased in all three echocardiographic views (p0.001), the reductions being greater in the long-axis view.By restoring the mitral apparatus geometry and competence, asymmetric annuloplasty with the IMR ETlogix ring provides good mid-term outcomes and helps left ventricular reverse remodeling in IMR.

Published
2014

44. Poster session 1: Wednesday 3 December 2014, 09:00-16:00Location: Poster area

Author

Tong, L., Huang, C., Ramalli, A., Tortoli, P., Luo, J., D'Hooge, J., Tzemos, N., Mordi, I., Bishay, T., Negishi, T., Hristova, K., Kurosawa, K., Bansal, M., Thavendiranathan, P., Yuda, S., Popescu, B., Vinereanu, D., Penicka, M., Marwick, T., Hamed, W., Kamel, M., Yaseen, R., El Barbary, H., Nemes, A., Kis, O., Gavaller, H., Kanyo, E., Forster, T., Angelis, A., Vlachopoulos, C., Ioakimidis, N., Felekos, I., Chrysohoou, C., Aznaouridis, K., Abdelrasoul, M., Terentes, D., Ageli, K., Stefanadis, C., Kurnicka, K., Domienik Karlowicz, J., Lichodziejewska, B., Goliszek, S., Grudzka, K., Krupa, M., Dzikowska Diduch, O., Ciurzynski, M., Pruszczyk, P., Capllonch, F. G., Ayerbe, J. L., Teis, A., Ferrer, E., Vallejo, N., Junca, G., Pla, R., Bayes Genis, A., Schwaiger, J., Knight, D., Gallimore, A., Schreiber, B., Handler, C., Coghlan, J., Bruno, R. M., Giardini, G., Malacrida, S., Catuzzo, B., Armenia, S., Brustia, R., Ghiadoni, L., Cauchy, E., Pratali, L., Kim, K., Lee, K., Cho, J., Yoon, H., Ahn, Y., Jeong, M., Park, J., Cho, S., Nastase, O., Enache, R., Mateescu, A., Botezatu, D., Ginghina, C., Gu, H., Sinha, M., Simpson, J., Chowienczyk, P., Fazlinezhad, A., Behesthi, A. T., Homaei, F., Mostafavi, H., Hosseini, G., Bakaeiyan, M., Boutsikou, M., Petrou, E., Dimopoulos, A., Dritsas, A., Leontiadis, E., Karatasakis, G., Sahin, S. T., Yurdakul, S., Yilmaz, N., Cengiz, B., Cagatay, Y., Aytekin, S., Yavuz, S., Karlsen, S., Dahlslett, T., Grenne, B., Sjoli, B., Smiseth, O., Edvardsen, T., Brunvand, H., Nasr, G., Nasr, A., Eleraki, A., Elrefai, S., Sonecki, P., Gustafsson, U., Naar, J., Stahlberg, M., Cerne, A., Capotosto, L., Rosato, Edoardo, D'Angeli, I., Azzano, A., Truscelli, G., Maio, M. D., Salsano, F., Terzano, C., Mangieri, E., Vitarelli, A., Renard, S., Najih, H., Mancini, J., Jacquier, A., Haentjens, J., Gaubert, J., Habib, G., Caminiti, G., D'Antoni, V., Cardaci, V., Conti, V., Volterrani, M., Ahn, J., Kim, D., Lee, H., Iliuta, L., Kim, S., Ryu, S., Ko, C., Pyun, Y., Yoon, S., Iudice, F. L., Esposito, R., Lembo, M., Santoro, C., Ballo, P., Mondillo, S., Simone, G. D., Galderisi, M., Hwang, Y., Kim, J., Moon, K., Yoo, K., Kim, C., Tagliamonte, E., Rigo, F., Cirillo, T., Caruso, A., Astarita, C., Cice, G., Quaranta, G., Romano, C., Capuano, N., Calabro', R., Zagatina, A., Zhuravskaya, N., Guseva, O., Huttin, O., Benichou, M., Voilliot, D., Venner, C., Micard, E., Girerd, N., Sadoul, N., Moulin, F., Juilliere, Y., Selton Suty, C., Baron, T., Christersson, C., Johansson, K., Flachskampf, F., Lee, S., Lee, J., Hur, S., Yun, J., Song, S., Kim, W., Ko, J., Nyktari, E., Bilal, S., Ali, S., Izgi, C., Prasad, S., Aly, M., Kleijn, S., Kandil, H., Kamp, O., Beladan, C., Calin, A., Rosca, M., Craciun, A., Gurzun, M., Calin, C., Mornos, C., Mornos, A., Ionac, A., Cozma, D., Crisan, S., Popescu, I., Ionescu, G., Petrescu, L., Camacho, S., Chulian, S. G., Carmona, R., Diaz, E., Giraldez, A., Gutierrez, A., Toro, R., Benezet, J., Antonini Canterin, F., Vriz, O., Carrubba, S. L., Poli, S., Leiballi, E., Zito, C., Careri, S., Caruso, R., Pellegrinet, M., Nicolosi, G., Kong, W., Kyu, K., Wong, R., Tay, E., Yip, J., Yeo, T., Poh, K., Correia, M., Delgado, A., Marmelo, B., Correia, E., Abreu, L., Cabral, C., Gama, P., Santos, O., Rahman, M., Borges, I. P., Peixoto, E., Peixoto, R., Marcolla, V., Okura, H., Kanai, M., Murata, E., Kataoka, T., Stoebe, S., Tarr, A., Pfeiffer, D., Hagendorff, A., Generati, G., Bandera, F., Pellegrino, M., Alfonzetti, E., Labate, V., Guazzi, M., Kuznetsov, V., Yaroslavskaya, E., Pushkarev, G., Krinochkin, D., Zyrianov, I., Carigi, S., Baldazzi, F., Bologna, F., Amati, S., Venturi, P., Grosseto, D., Biagetti, C., Fabbri, E., Arlotti, M., Piovaccari, G., Rahbi, H., Abdulhaq, A. B., Tleyjeh, I., Costantino, M., Tarsia, G., Innelli, P., Dores, E., Esposito, G., Matera, A., Trimarco, B., Mukred, K., Ashurov, R., Tanzilli, G., Merlo, M., Gigli, M., Stolfo, D., Pinamonti, B., Canterin, F. A., Muca, M., D'Angelo, G., Scapol, S., Nucci, M. D., Sinagra, G., Behaghel, A., Feneon, D., Fournet, M., Thebault, C., Martins, R., Mabo, P., Leclercq, C., Daubert, C., Donal, E., Pal, S. D., Chand, N. P., Sanjeev, A., Rajeev, M., Ankur, D., Gopal, S. R., Mzoughi, K., Zairi, I., Jabeur, M., Moussa, F. B., Chaabene, A. B., Kamoun, S., Mrabet, K., Fennira, S., Zargouni, A., Kraiem, S., Demkina, A., Hashieva, F., Krylova, N., Kovalevskaya, E., Potehkina, N., Zaroui, A., Said, R. B., Smaali, S., Rekik, B., Hlima, M. B., Mizouni, H., Mechmeche, R., Mourali, M., Malhotra, A., Sheikh, N., Dhutia, H., Siva, A., Narain, R., Merghani, A., Millar, L., Walker, M., Sharma, S., Papadakis, M., Siam Tsieu, V., Mansencal, N., Arslan, M., Deblaise, J., Dubourg, O., Boudiche, S., Larbi, N., Tababi, N., Hannachi, S., Chalbia, T., Halima, M. B., Boussada, R., Chistyakova, M. V., Govorin, A., Radaeva, E., Lipari, P., Bonapace, S., Valbusa, F., Rossi, A., Zenari, L., Lanzoni, L., Targher, G., Canali, G., Molon, G., Barbieri, E., Novo, G., Giambanco, S., Sutera, M., Bonomo, V., Giambanco, F., Rotolo, A., Evola, S., Assennato, P., Novo, S., Budnik, M., Piatkowski, R., Kochanowski, J., Opolski, G., Chatzistamatiou, E., Vagena, I. M., Manakos, K., Moustakas, G., Konstantinidis, D., Memo, G., Mitsakis, O., Kasakogias, A., Syros, P., Kallikazaros, I., Park, S., Kim, M., Shim, W., Marketou, M., Parthenakis, F., Kalyva, N., Pontikoglou, C., Maragkoudakis, S., Zacharis, E., Patrianakos, A., Maragoudakis, F., Papadaki, H., Vardas, P., Rodrigues, A., Perandini, L. A., Souza, T., Sa Pinto, A., Borba, E., Arruda, A., Furtado, M., Carvalho, F., Bonfa, E., Andrade, J., Hlubocka, Z., Malinova, V., Palecek, T., Danzig, V., Kuchynka, P., Dostalova, G., Zeman, J., Linhart, A., Trachanas, K., Vergi, N., Feretou, A., Corut, H., Sade, L. E., Ozin, B., Atar, I., Turgay, O., Muderrisoglu, H., Ledakowicz Polak, A., Polak, L., Krauza, G., Zielinska, M., Szulik, M., Streb, W., Wozniak, A., Lenarczyk, R., Sliwinska, A., Kalarus, Z., Kukulski, T., Nogueira, M., Branco, L., Agapito, A., Galrinho, A., Borba, A., Teixeira, P., Monteiro, A., Ramos, R., Cacela, D., Ferreira, R. C., Guala, A., Camporeale, C., Tosello, F., Canuto, C., Ridolfi, L., Traxanas, K., Marinov, R., Stamenov, G., Mihova, M., Persenska, S., Racheva, A., Plaskota, K., Trojnarska, O., Bartczak, A., Grajek, S., Bejiqi, R. R., Retkoceri, R., Bejiqi, H., Beha, A., Surdulli, S., Seya, M., Sasaoka, T., Hirasawa, K., Yoshikawa, S., Maejima, Y., Ashikaga, T., Hirao, K., Isobe, M., Dreyfus, J., Durand Viel, G., Cimadevilla, C., Brochet, E., Vahanian, A., Messika Zeitoun, D., Jin, C., Fang, F., Meng, F., Kam, K., Sun, J., Tsui, G., Wong, K., Wan, S., Yu, C., Lee, A., Cho, I. J., Chung, H., Heo, R., Ha, S., Hong, G., Shim, C., Chang, H., Ha, J., Chung, N., Moral, S., Gruosso, D., Galuppo, V., Teixido, G., Rodriguez Palomares, J., Gutierrez, L., Evangelista, A., Alexopoulos, A., Dawson, D., Nihoyannopoulos, P., Zainal, H. A., Ismail, J., Arshad, K., Ibrahim, Z., Lim, C., Rahman, E. A., Kasim, S., Peteiro, J., Barrio, A., Escudero, A., Bouzas Mosquera, A., Yanez, J., Martinez, D., Castro Beiras, A., Scali, M., Simioniuc, A., Mandoli, G., Lombardo, A., Massaro, F., Bello, V. D., Marzilli, M., Dini, F., Adachi, H., Tomono, J., Oshima, S., Ortega, G. M., Bustos, D. B., Garcia, R. L., Espino, A. S., Quinones, J. M., Ikuta, I., Lopez, M. R., Serrano, F. V., Gonzalez, J. B., Recio, M. G., Romano, G., D'Ancona, G., Pilato, G., Gesaro, G. D., Clemenza, F., Raffa, G., Scardulla, C., Sciacca, S., Lancellotti, P., Pilato, M., Addetia, K., Takeuchi, M., Maffessanti, F., Weinert, L., Hamilton, J., Mor Avi, V., Lang, R., Sugano, A., Seo, Y., Watabe, H., Kakefuda, Y., Aihara, H., Nishina, H., Ishizu, T., Fumikura, Y., Noguchi, Y., Aonuma, K., Luo, X., Shang, Q., Sammut, E. C., Chabinok, R., Jackson, T., Siarkos, M., Lee, L., Carr White, G., Rajani, R., Kapetanakis, S., Byrne, D., Walsh, J., Ellis, L., Mckiernan, S., Norris, S., King, G., Murphy, R., Katova, T., Simova, I., Kostova, V., Shuie, I., Ferferieva, V., Bogdanova, V., Castelon, X., Sasi, V., Domsik, P., Kalapos, A., Lengyel, C., Orosz, A., Grapsa, J., Demir, O., Sharma, R., Senior, R., Pilichowska, E., Zaborska, B., Baran, J., Stec, S., Kulakowski, P., Budaj, A., Herrera, J. E., Palacios, I. F., Mendoza, I., Marquez, J. A., Herrera, J. A., Octavio, J. A., Dempaire, G., Rotolo, M., Kosmala, W., Kaye, G., Saito, M., Negishi, K., Maceira, A. M., Ripoll, C., Cosin Sales, J., Igual, B., Salazar, J., Belloch, V., Dulai, R. S., Taylor, A., Gupta, S., and S. U. C., None

Published
2014

47. Cardiomiopatia Dilatativa

Author

Pinamonti, B, Secoli, G, Korcova, R, Brun, F, Di Lenarda, A, Sinagra, Gianfranco, Nicolosi, Antonini Canterin, Pavan, Piazza, Pinamonti, B, Secoli, G, Korcova, R, Brun, F, Di Lenarda, A, and Sinagra, Gianfranco

Subjects
ecocardiografia, cardiomiopatia dilatativa
Published
2008

48. Cardiomiopatia Ipertrofica Ostruttiva: la terapia medica

Author

Sinagra G, D'Agata B, Pinamonti B, Secoli G, Merignolo G, Merlo M, Pivetta A, Iorio A, Bardari S, Sabbadini G, Di Lenarda A, Sinagra, G, D'Agata, B, Pinamonti, B, Secoli, G, Merignolo, G, Merlo, M, Pivetta, A, Iorio, A, Bardari, S, Sabbadini, G, and Di Lenarda, A

Published
2008

49. Miocardite, cardiomiopatia infiammatoria e perimiocardite: possiamo fare ordine?

Author

Sinagra, Gianfranco, Pyxaras, S., Perkan, A., Brun, F., Sabbadini, G., Merlo, M., DI LENARDA, A., Pinamonti, B., Salvi, A., Rakar, S., Bussani, Rossana, Silvestri, Furio, Giacca, Mauro, Prati, Sinagra, Gianfranco, Pyxaras, S., Perkan, A., Brun, F., Sabbadini, G., Merlo, M., DI LENARDA, A., Pinamonti, B., Salvi, A., Rakar, S., Bussani, Rossana, Silvestri, Furio, and Giacca, Mauro

Subjects
Miocardite, cardiomiopatia, perimiocardite
Published
2007

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