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The META-WT project was designed to perform a 4-weeks seismic experiment in Germany with a dense seismic array of ~400 three-component geophones that covered (1) a 2.5km x 2.5km wind farm area in Brandenburg, Germany, with almost 200 wind turbines (WTs) and a well-studied subsurface structure and (2) a 20-km long radial line from the center of the wind farm with one geophone every half-kilometer. The objective was to capture the spatio-temporal seismic wave-field signature of the wind farm from continuous recordings of ambient noise. Due to the dense interstation distance and proposed geometry the experiment allowed for analyzing both small-scale wave field characteristics at an unprecedented spatial resolution and the longer distance radiation pattern of the wind farm. Waveform data is available from the GEOFON data centre, under network code XF, and is embargoed until Jan 2025.

The computation of time series for hard-rock site conditions, either as input motion for site response calculations or for applications to installations constructed on this site type, is a crucial step for seismic hazard assessment. The current state-of-the-art is to apply physics-based corrections to surface motions to eliminate the influence of site effects for retrieving the underlying bedrock motion. Here we evaluate the application of the generalized inversion method (GIT) for deconvolving surface recordings to obtain hard-rock time series at the amplification-free seismic bedrock. The method includes an event-specific phase scaling approach on the surface recordings that takes changes in the signal duration between the surface and the seismic bedrock into account.We choose a total of 90 KiK-net surface-downhole sites for validation which do not have a significant velocity contrast below the downhole sensors and with the latter being located at sufficient depth so that they are not significantly impaired by downgoing waves. By comparing the empirical predictions from surface recordings with time series that have been recorded at the downhole sensors, we assess the accuracy of the predictions. In contrast to empirical and one-dimensional modelling approaches, which significantly overestimate the level of hard-rock ground motion for frequencies greater than a few Hz, we find quite high correlations and small variations in both spectral shape and amplitude over the entire frequency range. This approach delivers a data set that facilitates the development of reference ground-motion models., The 28th IUGG General Assembly (IUGG2023) (Berlin 2023)

Characterizing and quantifying the effects of local soil conditions are essential for site-specific seismic hazard assessment and site response analysis. The high-frequency spectral decay parameter κr and its site-specific component, κ0, have gained popularity due to their abilities to characterize near-surface attenuation in situ. Values of κ0 for rock conditions are of particular interest for site-specific seismic hazard analysis for critical facilities. However, ground motions (GM) recorded at sites underlain by stiff soils or rocks are scarce, which limits the computation of κ0 values via the classic acceleration spectrum method. Recent research has found that κ values computed using the coda wave of a GM (i.e., the multiple-scattered wave that is less sensitive to the earthquake source and local site effects) can capture regional variations of the attenuation of hard rock materials regardless of the subsurface conditions near the surface. However, there are still large uncertainties in κ estimates based on the coda wave per GM, κr_coda, associated with the absence of consistent guidelines for the computation procedure and a user-orientated GM processing protocol. This work uses California GMs to examine the variability associated with the computation process of κr_coda, including the choice of onset of the coda wave and its duration. The objective of this paper is to understand and quantify the variabilities in κ values based on coda waves, which has potentially large implications in its applicability in future ground motion models.

Hintergrund: Krankenhauseinweisungen und -entlassungen stellen Brüche in der Patientenversorgung dar, die sich negativ auf Wiederaufnahmeraten, Versorgungskosten und die gesundheitsbezogene Lebensqualität auswirken können. Strukturierte Interventionen, die aus mehreren Komponenten bestehen, [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Hintergrund: Krankenhausentlassungen stellen nach wie vor eine Herausforderung für die Patientenversorgung dar. Mehrkomponenteninterventionen, die zu verschiedenen Zeitpunkten rund um den Krankenhausaufenthalt ansetzen, können zur Verbesserung der Versorgung beitragen. Fragestellung: [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Background: Adaptive study designs allow adaptations during an ongoing clinical trial provided that the type I error rate is maintained. Trials can be stopped at an interim stage or in case the trial is continued, adaptations like a sample size modification are possible. Whereas sample size calculations[for full text, please go to the a.m. URL], 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)

Flexible designs are an attractive option for clinical trials since they provide the possibility to react to unforeseen events during an ongoing trial while still controlling the type I error rate. Additionally, the application of an adaptive design may lead to a decrease in average sample size and,[for full text, please go to the a.m. URL], 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)

Nelle aree vulcaniche, come l’Isola d’Ischia, l’ampia variabilità litologica e l’alto gradiente geotermico richiedono analisi sempre più accurate per la definizione di specifici modelli di velocità e di attenuazione delle onde sismiche. Nel distretto vulcanico campano, modelli di velocità e attenuazione sempre più accurati sono stati ottenuti per il Vesuvio e per l’area dei Campi Flegrei, meno o del tutto assenti per quel che riguarda l’attenuazione per l’isola d’Ischia. È ben noto come la dettagliata conoscenza del modello di velocità possa fornire risultati più affidabili in termini di localizzazione dei terremoti locali. A tal proposito, è bene ricordare che, dal 1999, almeno 78 terremoti sono stati registrati ad Ischia (elenco aggiornato al 21 febbraio 2018) e sono stati localizzati utilizzando il modello disponibile per i Campi Flegrei, scelto sulla base di similarità geologiche e vulcanologiche. Pertanto, l’obiettivo di questo lavoro è la definizione di un modello 1-D in velocità e attenuazione della crosta più superficiale (fino a 2 km di profondità) di Ischia utilizzando tecniche di array applicate al rumore sismico e rapporti spettrali valutati su segnali sismici registrati da sismometri a larga banda installati sull’isola ai fini della sorveglianza e del monitoraggio.

This is an open-source site database for a total number of 1742 earthquake recording sites in the K-NET (Kyoshin network) and KiK-net (Kiban Kyoshin network) networks in Japan. This database contains site characterization parameters directly derived from available velocity profiles, including average wave velocities, bedrock depths, and velocity contrast. Meanwhile, it also consists of parameters obtained from earthquake horizontal-to-vertical spectral ratio (HVSR), e.g., peak frequency, amplitude, width and prominence. In addition, the site database also comprises topographic and geological proxies inferred from regional models or maps. Each parameter is derived in a consistent manner for all sites. This site database can benefit the application of machine learning techniques in studies on site amplifications. Besides, it can facilitate, for instances, the search of the optimal site parameter(s) in depicting site amplification, the development and testing of new or existing prediction models or methodologies. This zip file contains earthquake HVSR data, including metadata and plots of automatically identified peaks (frequency, amplitude, prominence and width) at 1700+ K-NET and KiK-net strong-motion recordings stations. This MATLAB code is for automatically picking peaks (frequency, amplitude, prominence and width) from HVSR curves.

Hintergrund: Amitriptylin ist eines der am häufigsten verschriebenen Antidepressiva und wird bei zahlreichen weiteren Konditionen (z.B. Harninkontinenz, Kardiovaskuläre Erkrankungen, Parkinson, Allergien, Übelkeit, Hyperacidität, COPD) eingesetzt. Durch eine veränderte Pharmakokinetik[zum vollständigen Text gelangen Sie über die oben angegebene URL], 53. Kongress für Allgemeinmedizin und Familienmedizin

DESTRESS is a Horizon-2020 supported project (Topic: Demonstration of renewable electricity and heating/cooling technologies) that is concerned with creating EGS (enhanced geothermal systems) for the more economical, sustainable and environmentally responsible exploitation of underground heat. The international consortium, representing academic, geothermal sites and industry, will utilize the latest developments in the use of hydraulic, chemical and thermal treatments for enhancing the productivity of geothermal reservoirs, with considerable interaction with various interests groups and the thorough assessment of the associated risk, in particular that associated with induced seismicity. The GFZ workgroup "Early warning and Impact Forecasting" is involved in the exposure modelling, vulnerability analysis and building monitoring of communities near geothermal production facilities, making use of tools developed both in previous and ongoing projects. Data are available under network code 1M at the GEOFON data centre.

In this study data and results of a high-resolution experiment in Cephalonia (Greece) regarding empirical basin effects are presented. A total of 59 velocimeters and 17 accelerometers were deployed in the basin of Argostoli Cephalonia (Greece), for a period of 7 months (September 2011–April 2012). Due to high seismicity of the western Greece and surrounding area this array recorded thousands of local, regional and global events. Data used in this work come from a selection of 162 regional and local earthquakes, 3 km ≤ R ≤ 600 km, with magnitude range, 1.0 ≤ M ≤ 5.2. Based on high signal-to-noise ratio recordings and two selected reference stations, variation of several intensity measures (PGA, PGV, Arias Intensity, Cumulative Absolute Velocity), significant duration, HVSR and SSR of ground motion recordings on soil sites within the basin is carefully examined for a range of frequencies of engineering interest. Comparison of results with a detailed 2D geologic model shows a good consistency both in amplification and frequency domain. Influence of “reference” site on ground motion variation of soil sites is also discussed in light of our results. Finally, it is suggested that 2D or/and 3D theoretical modeling should be performed given the availability of geological and geophysical parameters to define a realistic model of the basin. Results of this study can undoubtedly serve in model validation and improvement of ground motion simulation tools.

The MI-DAM project will develop a robust, low-cost, and adaptable system that includes an early warning element and time-variable fragility functions. The system will continuously monitor the health of hydroelectric dams and the surrounding slopes, undertake on-site processing of recordings by multi-parameter sensors, and forward the most relevant information to response centers (e.g., civil protection). As an example, the project will focus on the Toktogul dam in Central Kyrgyzstan. Data are available under network code 1M at the GEOFON data centre.