251 results on '"Pillaiyar, Thanigaimalai"'
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2. Synthesis and structure–activity relationships of ticlopidine derivatives and analogs as inhibitors of ectonucleotidase CD39
3. Targeting tyrosinase in hyperpigmentation: Current status, limitations and future promises
4. ACKR3 agonism induces heterodimerization with chemokine receptor CXCR4 and attenuates platelet function.
5. Hemin‐induced platelet activation is regulated by the ACKR3 chemokine surface receptor and has implications for passivation of vulnerable atherosclerotic plaques.
6. Inhibitor induced conformational changes in SARS-COV-2 papain-like protease
7. Hemin-induced platelet activation is regulated via ACKR3 chemokine surface receptor - implications for passivation of vulnerable atherosclerotic plaque
8. ACKR3 agonism induces heterodimerization with chemokine receptor CXCR4 and attenuates platelet function
9. Structure-activity relationships of agonists for the orphan G protein-coupled receptor GPR27
10. Nonpeptidic Irreversible Inhibitors of SARS-CoV‑2 Main Protease with Potent Antiviral Activity.
11. Novel Small-Molecule Atypical Chemokine Receptor 3 Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy.
12. A medicinal chemistry perspective of drug repositioning: Recent advances and challenges in drug discovery
13. Recent discovery and development of inhibitors targeting coronaviruses
14. Correction to “Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity”
15. Design, synthesis and biological evaluation of suramin-derived dual antagonists of the proinflammatory G protein-coupled receptors P2Y2 and GPR17
16. Design and synthesis of sulfonamidophenylethylamides as novel cardiac myosin activator
17. Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity
18. Candidate Drugs for the Potential Treatment of Coronavirus Diseases
19. Development of Ligands for the Super Conserved Orphan G Protein-Coupled Receptor GPR27 with Improved Efficacy and Potency
20. Discovery of Potent Agonists for the Predominant Variant of the Orphan MAS-Related G Protein-Coupled Receptor X4 (MRGPRX4)
21. Design and synthesis of sulfonamidophenylethylureas as novel cardiac myosin activator
22. Recent development of signaling pathways inhibitors of melanogenesis
23. Exploration of flexible phenylpropylurea scaffold as novel cardiac myosin activators for the treatment of systolic heart failure
24. Downregulation of melanogenesis: drug discovery and therapeutic options
25. Multi-omics for COVID-19: driving development of therapeutics and vaccines
26. Discovery of enantioselectivity of urea inhibitors of soluble epoxide hydrolase
27. Cell Type-Specific Anti-Viral Effects of Novel SARS-CoV-2 Main Protease Inhibitors
28. Discovery of Polyphenolic Natural Products as SARS-CoV-2 Mpro Inhibitors for COVID-19
29. Synthesis and Structure-Activity Relationships of Ticlopidine Derivatives and Analogs as Inhibitors of Ectonucleotidase Cd39
30. Superconserved receptors expressed in the brain: Expression, function, motifs and evolution of an orphan receptor family
31. Discovery of Polyphenolic Natural Products as SARS-CoV-2 Mpro Inhibitors for COVID-19
32. Design, synthesis, and structure–activity relationships of diindolylmethane derivatives as cannabinoid CB2 receptor agonists
33. Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice
34. Discovery and Development of First-in-Class ACKR3/CXCR7 Superagonists for Platelet Degranulation Modulation
35. Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure–Activity Relationships, Antiviral Activity, and X-ray Structure Determination
36. Super-conserved receptors expressed in the brain: biology and medicinal chemistry efforts
37. Small Molecule Thioesters as SARS-CoV-2 Main Protease inhibitors: Enzyme inhibition and mechanism, structure-activity relationship, antiviral activity, and X-ray structure determination
38. 2,2,2‐Trifluoroethanol‐mediated hydroarylation of fluorinated alkynes with indoles: Application to diindolylmethanes
39. The Activation of GPR27 Increases Cytosolic L-Lactate in 3T3 Embryonic Cells and Astrocytes
40. Design, synthesis, and structure–activity relationships of diindolylmethane derivatives as cannabinoid CB2 receptor agonists.
41. Discovery of Polyphenolic Natural Products as SARS-CoV-2 M pro Inhibitors for COVID-19.
42. Activating endogenous resolution pathways by soluble epoxide hydrolase inhibitors for the management of COVID‐19
43. Design, synthesis and anticancer activity of 2-amidomethoxy-1,4-naphthoquinones and its conjugates with Biotin/polyamine
44. Involvement of GPR17 in Neuronal Fibre Outgrowth
45. 2‐Substituted thienotetrahydropyridine derivatives: Allosteric ectonucleotidase inhibitors
46. 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents
47. Iodine-catalyzed electrophilic substitution of indoles: Synthesis of (un)symmetrical diindolylmethanes with a quaternary carbon center
48. Kinases as Potential Therapeutic Targets for Anti-coronaviral Therapy
49. Design, Synthesis, and Unprecedented Interactions of Covalent Dipeptide-Based Inhibitors of SARS-CoV-2 Main Protease and Its Variants Displaying Potent Antiviral Activity
50. Involvement of GPR17 in Neuronal Fibre Outgrowth
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