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1. La telecardiologia in Riabilitazione Cardiologica: nostra esperienza nel post-IMA

Author

Giallauria F., Manakos A., De Lorenzo A., Pilerci F., de Cristofaro A., Ianniccelli A., Lucci R., Di Palma U., Aurino M., DEL FORNO, DOMENICO, VIGORITO, CARLO, Giallauria, Francesco, Manakos, A, De Lorenzo, A, Pilerci, F, Iannicelli, A, de Cristofaro, A, Lucci, R, Di Palma, U, Del Forno, D, Aurino, M, Vigorito, Carlo, Giallauria, F., Manakos, A., De Lorenzo, A., Pilerci, F., de Cristofaro, A., Ianniccelli, A., Lucci, R., Di Palma, U., Aurino, M., and DEL FORNO, Domenico

Published
2004

2. Effetti favorevoli di un ciclo di Riabilitazione Cardiologica intensivo e prolungato sui parametri ergospirometrici e lipidici nel post-IMA

Author

De Cristofaro A., Lucci R., Giallauria F., De Lorenzo A., Manakos A., Pilerci F., Aurino M., DEL FORNO, DOMENICO, VIGORITO, CARLO, de Cristofaro, A, Del Forno, D, Lucci, R, Giallauria, Francesco, De Lorenzo, A, Manakos, A, Pilerci, F, Aurino, M, Vigorito, Carlo, De Cristofaro, A., DEL FORNO, Domenico, Lucci, R., Giallauria, F., De Lorenzo, A., Manakos, A., Pilerci, F., and Aurino, M.

Published
2004

3. Exercise-induced improvement of heart rate recovery in young women with polycystic ovary syndrome

Author

GIALLAURIA, FRANCESCO, MARESCA, LUIGI, VIGORITO, CARLO, Orio F, Palomba S, Lucci R, Cascella T, Vitelli A, De Lorenzo A, Manakos A, D'Agostino M, Psaroudaki M, Pilerci F, Pilerci D, Colao A, Giallauria, Francesco, Orio, F, Palomba, S, Lucci, R, Cascella, T, Vitelli, A, De Lorenzo, A, Manakos, A, D'Agostino, M, Maresca, Luigi, Psaroudaki, M, Pilerci, F, Pilerci, D, Colao, A, and Vigorito, Carlo

Published
2006

4. Exercise training prevents left venticular remodeling, reduces NT-pro-BNP and improves cardiovascular function in patients with acute myocardial infarction and moderate left venticular dysfunction

Author

Giallauria F., CIRILLO, PLINIO, Lucci R., Pacileo M., De Lorenzo A., Manakos A., Pilerci F., DEL FORNO, DOMENICO, CHIARIELLO, MASSIMO, VIGORITO, CARLO, Giallauria, F., Cirillo, Plinio, Lucci, R., Pacileo, M., De Lorenzo, A., Manakos, A., Pilerci, F., DEL FORNO, Domenico, Chiariello, Massimo, and Vigorito, Carlo

Published
2006

5. Exercise training prevents left ventricular remodeling, reduces NT-pro-BNP and improves cardiovascular function in patients with acute myocardial infarction and moderate left ventricular dysfunction

Author

GIALLAURIA, FRANCESCO, MARESCA, LUIGI, VIGORITO, CARLO, CIRILLO, PLINIO, Lucci R, Pacileo M, De Lorenzo A, Manakos A, Pilerci F, Psaroudaki M, D'Agostino M, Vitelli A, Pilerci D, Del Forno D, Chiariello M, Giallauria, Francesco, Cirillo, Plinio, Lucci, R, Pacileo, M, De Lorenzo, A, Manakos, A, Pilerci, F, Psaroudaki, M, D'Agostino, M, Vitelli, A, Maresca, Luigi, Pilerci, D, Del Forno, D, Chiariello, M, and Vigorito, Carlo

Published
2006

7. Valore predittivo dell'NT-pro BNP sul rimodellamento ventricolare sinistro: ruolo del training fisico

Author

GIALLAURIA, FRANCESCO, MARESCA, LUIGI, VIGORITO, CARLO, CIRILLO, PLINIO, Vitale DF, Lucci R, Pacileo M, De Lorenzo A, Pilerci F, Manakos A, D'Agostino M, Psaroudaki M, Vitelli A, Mancini M, Giallauria, Francesco, Cirillo, Plinio, Vitale, Df, Lucci, R, Pacileo, M, De Lorenzo, A, Pilerci, F, Manakos, A, D'Agostino, M, Psaroudaki, M, Vitelli, A, Maresca, Luigi, Mancini, M, and Vigorito, Carlo

Published
2006

8. Effetti di un programma prolungato di Riabilitazione Cardiologica sulla funzione autonomica dopo infarto del miocardio acuto

Author

Giallauria F, Maresca L., Vitelli A., Lucci R., De Lorenzo A., D’Agostino M., Manakos A, Pilerci F, Psaroudaki M., Pilerci D., Bloise A., Mancini M., DEL FORNO, DOMENICO, VIGORITO, CARLO, Giallauria, F, Maresca, L., Vitelli, A., Lucci, R., De Lorenzo, A., D’Agostino, M., Manakos, A, Pilerci, F, Psaroudaki, M., Pilerci, D., Bloise, A., Mancini, M., DEL FORNO, Domenico, and Vigorito, Carlo

Published
2006

9. Cardiopulmonary impairment in young women with polycystic ovary syndrome

Author

GIALLAURIA, FRANCESCO, MARESCA, LUIGI, VIGORITO, CARLO, Orio F, Lucci R, Vuolo L, De Lorenzo A, Grieco A, Manakos A, Pilerci F, Psaroudaki M, D'Agostino M, Vitelli A, Pilerci D, Lombardi G, Giallauria, Francesco, Orio, F, Lucci, R, Vuolo, L, De Lorenzo, A, Grieco, A, Manakos, A, Pilerci, F, Psaroudaki, M, D'Agostino, M, Maresca, Luigi, Vitelli, A, Pilerci, D, Lombardi, G, and Vigorito, Carlo

Published
2006

10. Valore predittivo dell’NT-pro-BNP sul rimodellamento ventricolare sinistro: ruolo del training fisico

Author

Giallauria F, CIRILLO, PLINIO, Vitale D. F., Lucci R., Pacileo M., De Lorenzo A., Pilerci F, Manakos A., D’Agostino M., Psaroudaki M., Vitelli A., Maresca L., Mancini M., DEL FORNO, DOMENICO, CHIARIELLO, MASSIMO, VIGORITO, CARLO, Giallauria, F, Cirillo, Plinio, Vitale, D. F., Lucci, R., Pacileo, M., De Lorenzo, A., Pilerci, F, Manakos, A., D’Agostino, M., Psaroudaki, M., Vitelli, A., Maresca, L., Mancini, M., DEL FORNO, Domenico, Chiariello, Massimo, and Vigorito, Carlo

Published
2006

11. Effetti di un programma prolungato di Riabilitazione Cardiologica sulla funzione autonomica dopo infarto miocardico acuto

Author

GIALLAURIA, FRANCESCO, MARESCA, LUIGI, VIGORITO, CARLO, Vitelli A, Lucci R, De Lorenzo A, D'Agostino A, Manakos A, Pilerci F, Psaroudaki M, Pilerci D, Bloise A, Mancini M, Del Forno D, Giallauria, Francesco, Maresca, Luigi, Vitelli, A, Lucci, R, De Lorenzo, A, D'Agostino, A, Manakos, A, Pilerci, F, Psaroudaki, M, Pilerci, D, Bloise, A, Mancini, M, Del Forno, D, and Vigorito, Carlo

Published
2006

13. Effetti favorevoli del training fisico sui livelli plasmatici dell'NT-pro BNP in pazienti anziani dopo infarto miocardico acuto

Author

GIALLAURIA, FRANCESCO, MARESCA, LUIGI, VIGORITO, CARLO, Vitelli A, Lucci R, De Lorenzo A, D'Agostino M, Bloise A, Pilerci F, Psaroudaki M, Pilerci D, Mancini M, Chieffo C, Giallauria, Francesco, Vitelli, A, Lucci, R, De Lorenzo, A, D'Agostino, M, Maresca, Luigi, Bloise, A, Pilerci, F, Psaroudaki, M, Pilerci, D, Mancini, M, Chieffo, C, and Vigorito, Carlo

Published
2006

14. Training fisico e funzione autonomica in giovani donne affette da sindrome dell'ovaio policistico

Author

GIALLAURIA, FRANCESCO, MARESCA, LUIGI, VIGORITO, CARLO, Orio F, Palomba S, Lucci R, Cascella T, Vitelli A, De Lorenzo A, D'Agostino M, Manakos A, Pilerci F, Psaroudaki M, Pilerci D, Mancini M, Colao A, Giallauria, Francesco, Orio, F, Palomba, S, Lucci, R, Cascella, T, Vitelli, A, Maresca, Luigi, De Lorenzo, A, D'Agostino, M, Manakos, A, Pilerci, F, Psaroudaki, M, Pilerci, D, Mancini, M, Colao, A, and Vigorito, Carlo

Published
2006

15. Insulino-resistenza e funzione cardiopolmonare in giovani donne affette da sindrome dell'ovaio policistico

Author

GIALLAURIA, FRANCESCO, MARESCA, LUIGI, VIGORITO, CARLO, Orio F, Lucci R, Vuolo L, De Lorenzo A, Grieco A, D'Agostino M, Vitelli A, Manakos A, Pilerci F, Psaroudaki M, Pilerci D, Mancini M, Lombardi G, Giallauria, Francesco, Orio, F, Lucci, R, Vuolo, L, De Lorenzo, A, Grieco, A, D'Agostino, M, Maresca, Luigi, Vitelli, A, Manakos, A, Pilerci, F, Psaroudaki, M, Pilerci, D, Mancini, M, Lombardi, G, and Vigorito, Carlo

Published
2006

16. Long-term effect of cardiac rehabilitation on cardiovascular capacity and on autonomic balance in type 2 diabetic patients after acute myocardial infarction

Author

GIALLAURIA, FRANCESCO, MARESCA, LUIGI, VIGORITO, CARLO, Lucci R, Manakos A, Pilerci F, De Lorenzo A, Psaroudaki M, D'Agostino M, Vitelli A, Pilerci D, Del Forno D, Giallauria, Francesco, Lucci, R, Manakos, A, Pilerci, F, De Lorenzo, A, Psaroudaki, M, D'Agostino, M, Maresca, Luigi, Vitelli, A, Pilerci, D, Del Forno, D, and Vigorito, Carlo

Published
2006

17. Effetti di un programma di Riabilitazione Cardiologica a lungo termine dopo infarto miocardico acuto sulla funzione autonomica in pazienti con diabete mellito di tipo 2

Author

GIALLAURIA, FRANCESCO, MARESCA, LUIGI, VIGORITO, CARLO, Lucci R, Manakos A, De Lorenzo A, Vitelli A, Pilerci F, Scaglione A, Psaroudaki M, D'Agostino M, Pilerci D, Mancini M, Chieffo C, Del Forno D, Giallauria, Francesco, Maresca, Luigi, Lucci, R, Manakos, A, De Lorenzo, A, Vitelli, A, Pilerci, F, Scaglione, A, Psaroudaki, M, D'Agostino, M, Pilerci, D, Mancini, M, Chieffo, C, Del Forno, D, and Vigorito, Carlo

Published
2006

18. Effetti di un programma di Riabilitazione Cardiologica a lungo termine dopo infarto del miocardio acuto sulla funzione autonomia in pazienti con diabete mellito di tipo 2

Author

Giallauria F, Maresca L., Lucci R., Manakos A., De Lorenzo A., Vitelli A., Pilerci F, Scaglione A., Psaroudaki M., D’Agostino M., Chieffo C., DEL FORNO, DOMENICO, VIGORITO, CARLO, Giallauria, F, Maresca, L., Lucci, R., Manakos, A., De Lorenzo, A., Vitelli, A., Pilerci, F, Scaglione, A., Psaroudaki, M., D’Agostino, M., Chieffo, C., DEL FORNO, Domenico, and Vigorito, Carlo

Published
2006

19. Improvement of heart rate recovery after exercise training in older people

Author

Giallauria F., Pilerci F., De Lorenzo A., Manakos A., Lucci R., DEL FORNO, DOMENICO, VIGORITO, CARLO, Giallauria, F., DEL FORNO, Domenico, Pilerci, F., De Lorenzo, A., Manakos, A., Lucci, R., and Vigorito, Carlo

Subjects
Male, Aging, Cardiac Rehabilitation, Anaerobic Threshold, Vagus Nerve, Carbon Dioxide, Prognosis, Oxygen, Cardiovascular Diseases, Heart Rate, Cause of Death, Exercise Test, Humans, Female, Exercise, Aged, Retrospective Studies
Abstract

Twenty-four subjects aged 70 and older were retrospectively selected from our archives and screened for symptoms of cardiovascular disease. Baseline exercise test was negative for myocardial ischemia in all subjects. All subjects had completed an 8-week program, performed for a variety of indications and consisting of an aerobic physical training program including 30 minutes of cycling three times per week at 65% to 75% of maximum heart rate achieved at peak exercise test performed at enrollment, an educational intervention, dietary advice, and psychological support. All subjects underwent a cardiopulmonary exercise test (CPX) before and at the end of exercise training. At the end of each CPX, peak oxygen uptake (VO2peak), the rate of increase of ventilation per unit of increase of carbon dioxide production (VE/VCO2slope), and HRR were recorded. Twenty-five healthy subjects younger than 60 with no evidence of exercise-induced myocardial ischemia and not enrolled in any exercise training program were also retrospectively selected from our archives and used as a control group for analyzing HRR. These patients performed two exercise tests several weeks apart. Several studies have shown that changes in vagal tone can be used as an outcome tool that helps identify patients or subjects with or without cardiovascular disease at risk for a cardiovascular event, although the evidence of a prognostic value of HRR in older subjects without cardiovascular disease is rather poor. In this study, exercise training resulted in HRR improvement in healthy elderly subjects, suggesting that exercise training improves vagal/sympathetic balance in older subjects without cardiovascular disease as well. Whether the observed improvement in HRR may have long-term beneficial prognostic effects was not the aim of the study, although a beneficial effect might be postulated, in light of the Framingham data

Published
2005

20. La valutazione del paziente con insufficienza cardiaca: il test cardiopolmonare

Author

GIALLAURIA, FRANCESCO, LUCCI, ROSA, DEL FORNO, DOMENICO, VIGORITO, CARLO, Romano M, Del Lorenzo A, Manakos A, Pilerci F, Psaroudaki M, De Cristofaro A, Spinelli R, Giallauria, Francesco, Romano, M, Del Lorenzo, A, Manakos, A, Pilerci, F, Psaroudaki, M, De Cristofaro, A, Lucci, Rosa, Spinelli, R, DEL FORNO, Domenico, and Vigorito, Carlo

Subjects
insufficienza cardiaca, test cardiopolmonare, TECP
Published
2005

25. Training aerobico e heart rate recovery (HRR) nel soggetto anziano

Author

GIALLAURIA, FRANCESCO, MARESCA, LUIGI, VIGORITO, CARLO, Lucci R, Manakos A, Pilerci F, De Lorenzo A, D'Agostino M, Psaroudaki M, de Cristofaro A, Del Forno D, Giallauria, Francesco, Lucci, R, Manakos, A, Pilerci, F, De Lorenzo, A, D'Agostino, M, Psaroudaki, M, Maresca, Luigi, de Cristofaro, A, Del Forno, D, and Vigorito, Carlo

Published
2005

32. Long-Term Effects Of Cardiac Rehabilitation On End-Exercise Heart Rate Recovery After Myocardial Infarction

Author

Marianna Psaroudaki, Carlo Vigorito, Francesco Pilerci, Francesco Giallauria, Athanasio Manakos, Domenico Del Forno, Rosa Lucci, Mariantonietta D'Agostino, Anna De Lorenzo, Giallauria, F, DE LORENZO, A, Pilerci, F, Manakos, A, Lucci, R, Psaroudaki, M, Dagostino, M, DEL FORNO, D, Vigorito, Carlo, Giallauria, F., De Lorenzo, A., Pilerci, F., Manakos, A., Lucci, R., Psaroudaki, M., D'Agostino, M., and DEL FORNO, Domenico

Subjects
Male, medicine.medical_specialty, Time Factors, Epidemiology, medicine.medical_treatment, Myocardial Infarction, Motor Activity, law.invention, Oxygen Consumption, Randomized controlled trial, Heart Rate, law, Internal medicine, Heart rate, Humans, Medicine, In patient, Myocardial infarction, Vagal tone, Exercise Tolerance, Rehabilitation, business.industry, Follow up studies, Middle Aged, medicine.disease, Exercise Therapy, Treatment Outcome, medicine.anatomical_structure, Cardiology, Female, Cardiology and Cardiovascular Medicine, business, human activities, Follow-Up Studies, Artery
Abstract

Heart rate recovery (HRR) is a marker of vagal tone that is a powerful predictor of mortality in patients with coronary artery disease.This study aims at evaluating the effects of long-term exercise training on HRR after acute myocardial infarction (AMI), in order to clarify whether prolonged exercise training could maintain a long-term improvement of HRR.Forty-four patients after AMI were enrolled in a 3-month hospital-based exercise training programme. At the end, patients were subdivided into two groups: group A (n=22), patients discharged with a specific home-based exercise training programme and instructions for improving leisure-time physical activity; group B (n=22), patients discharged with generic instructions to maintain physical activity. All patients underwent a cardiopulmonary exercise test before, at the end of 3 months exercise training and at 6 months follow-up.At the end of the hospital-based exercise training programme we observed an increase in peak oxygen consumption [VO2peak; from 13.9+/-3.6 to 18+/-2.7 ml/kg per min (A) and from 14.1+/-3.9 to 17.9+/-2.1 ml/kg per min (B), P0.001] and in HRR [from 17.1+/-1.8 to 23.4+/-1.4 beats/min (A), and from 18.8+/-2.1 to 24.3+/-1.9 beats/min (B), P0.001]. At 6 months' follow-up we observed a further improvement in VO2peak (from 18.0+/-2.7 to 20.3+/-2.7 ml/kg per min, P0.001) and in HRR (from 23.4+/-1.4 to 27.8+/-2.1 beats/min, P0.001) in group A, but a significant decrease in VO2peak and in HRR in group B (P0.001).Long-term exercise training is useful for maintaining or improving the beneficial results of the standard 3-month exercise training programme on cardiovascular capacity and HRR. This observation may bear beneficial prognostic effects on patients after AMI.

Published
2006

33. Efficacy of telecardiology in improving the results of cardiac rehabilitation after acute myocardial infarction

Author

Anna De Lorenzo, Alessandra Vitelli, Francesco Giallauria, Carlo Vigorito, Athanasio Manakos, Domenico Del Forno, Marianna Psaroudaki, Luigi Maresca, Francesco Pilerci, Mariantonietta D'Agostino, Rosa Lucci, Giallauria, F., Lucci, R., Pilerci, F., De Lorenzo, A., Manakos, A., Psaroudaki, M., Dagostino, M., Vitelli, A., Maresca, L., DEL FORNO, Domenico, and Vigorito, Carlo

Subjects
Pulmonary and Respiratory Medicine, Male, medicine.medical_specialty, Psychometrics, medicine.medical_treatment, Myocardial Infarction, lcsh:Medicine, Group B, Quality of life, Internal medicine, Heart rate, medicine, Humans, Myocardial infarction, Aged, Rehabilitation, medicine.diagnostic_test, business.industry, lcsh:R, Case-control study, telecardiology, Middle Aged, medicine.disease, Home Care Services, Telemedicine, cardiac rehabilitation, Case-Control Studies, Physical therapy, Electrocardiography, Ambulatory, Exercise Test, Quality of Life, Anxiety, Patient Compliance, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Electrocardiography, Program Evaluation
Abstract

Background: This study was addressed to verify if Telecardiology (TC) improves the results of Cardiac Rehabilitation in patients following a home-based Cardiac Rehabilitation Program (CRP) after acute myocardial infarction (AMI). Materials and Methods: We studied three groups of patients after AMI: Group A (control group): 15 patients, who followed a standard in-hospital CRP of 3 weekly sessions of 2 months duration; Group B (study group): 15 patients, who were enrolled in a home-based CRP of similar duration and were monitored by TC with the aid of an ecg-device (Sorin Life Watch CG 6106); Group C (second control group): 15 patients, who followed a home-based CRP without ecgmonitoring by TC. All patients performed a symptom-limited exercise testing at the beginning of the CRP. Psychometric data (STAI-Y1, STAI-Y2, BDI) were also evaluated. At the end of the CRP all patients underwent repeated exercise testing and psychometric evaluation. Results: TC applied to the home-based CRP was associated with a good compliance to the program. Compared to Group C, in Group B we observed an increase of maximal heart rate, exercise duration, maximal work-load, and an improvement of anxiety, a trend to reduction of depression, and an improvement of quality of life. These results were very similar to Group A patients following a hospital-based CRP. Conclusions: TC improves compliance, functional capacity and psychological profile of patients undergoing a home-based CRP, compared to patients enrolled in a homebased CRP without ecg-monitoring by Telecardiology.

Published
2006

34. Reduction of N terminal-pro-brain (B-type) natriuretic peptide levels with exercise-based cardiac rehabilitation in patients with left ventricular dysfunction after myocardial infarction

Author

Francesco Giallauria, Francesco Pilerci, Domenico Del Forno, Carlo Vigorito, Anna De Lorenzo, Rosa Lucci, Athanasio Manakos, Mariantonietta D'Agostino, Marianna Psaroudaki, Giallauria, F., De Lorenzo, A., Pilerci, F., Manakos, A., Lucci, R., Psaroudaki, M., D'Agostino, M., DEL FORNO, Domenico, and Vigorito, Carlo

Subjects
Male, medicine.medical_specialty, Epidemiology, medicine.drug_class, Heart Ventricles, Diastole, Myocardial Infarction, Peptide hormone, Ventricular Dysfunction, Left, Internal medicine, Natriuretic Peptide, Brain, medicine, Natriuretic peptide, Myocyte, Humans, Myocardial infarction, Exercise physiology, Exercise, Echocardiography, Doppler, Pulsed, business.industry, Middle Aged, medicine.disease, Brain natriuretic peptide, Myocardial Contraction, Exercise Therapy, Treatment Outcome, Cardiology, Myocardial infarction complications, Female, Cardiology and Cardiovascular Medicine, business, Biomarkers
Abstract

Introduction N-terminal-pro-brain (B-type) natriuretic peptide (NT-pro-BNP) is a peptide hormone released from ventricles in response to myocyte stretch. The aim of the study was to investigate the influence of exercise training on plasma NT-pro-BNP to verify if this parameter could be used as a biological marker of left ventricular remodelling in myocardial infarction patients undergoing an exercise training programme.Methods Forty-four patients after myocardial infarction were enrolled into a cardiac rehabilitation programme, and were randomized in two groups of 22 patients each. Group A patients followed a 3-month exercise training programme, while group B patients received only routine recommendations. All patients underwent NT-pro-BNP assay, and cardiopulmonary exercise test before hospital discharge and after 3 months.Results In Group A, exercise training reduced NT-pro-BNP levels (from 1498 +/- 438 to 470 +/- 375pg/ml, P = 0.0026), increased maximal (V-O2peak +4.3 +/- 2.9 ml/kg per min, P < 0.001; Power(max) +38 +/- 7, P < 0.001) exercise parameters and work efficiency (Power(max)/V-O2peak + 1.3 +/- 0.4 Power/ml per kg per min, P < 0.001); there was also an inverse correlation between changes in NT-pro-BNP levels and in V-O2peak (r = -0.72, P < 0.001), E-wave (r = -0.51, P < 0.001) and E/A ratio (r = 0.59, P < 0.001). In group B, at 3 months, no changes were observed in NT-pro-BNP levels, exercise and echocardiographic parameters.Conclusion Three months exercise training in patients with moderate left ventricular systolic dysfunction after myocardial infarction induced a reduction in NT-pro-BNP levels, an improvement of exercise capacity and early left ventricular diastolic filling, without negative left ventricular remodelling. Whether the reduction of NT-pro-BNP levels could be useful as a surrogate marker of favourable left ventricular remodelling at a later follow-up remains to be further explored.

Published
2006

35. Role of smokers in the household and of cardiac rehabilitation in smoking behaviour after acute myocardial infarction

Author

Marianna Psaroudaki, Francesco Pilerci, Teresa Paragliola, Francesco Giallauria, Rosa Lucci, Anna De Lorenzo, Domenico Del Forno, Athanasio Manakos, Carlo Vigorito, Mariantonietta D'Agostino, Giallauria, F., Paragliola, T., Pilerci, F., DEL FORNO, Domenico, De Lorenzo, A., Manakos, A., Lucci, R., Psaroudaki, M., D'Agostino, M., and Vigorito, Carlo

Subjects
Counseling, Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Myocardial Infarction, lcsh:Medicine, Smoking Prevention, Group B, Nuclear Family, Behavior Therapy, Risk Factors, Internal medicine, Humans, Medicine, In patient, Myocardial infarction, Medical prescription, smoking behaviour, Exercise, Aged, Secondary prevention, Family Characteristics, Chi-Square Distribution, Rehabilitation, business.industry, Smoking, lcsh:R, Behavioural intervention, Long term maintenance, Middle Aged, medicine.disease, cardiac rehabilitation, Data Interpretation, Statistical, Physical therapy, Patient Compliance, Smoking Cessation, Cardiology and Cardiovascular Medicine, business, secondary prevention, Follow-Up Studies
Abstract

Objects: This study aims to evaluate the influence of household smokers and of a prolonged, comprehensive home-based Cardiac Rehabilitation Program (CRP) on patient’s long term smoking behaviour after AMI. Methods: 164 male post-AMI patients, all smokers until the day of AMI, were subdivided into three groups: Group A (n=54): patients with recent AMI, discharged from hospital without enrolment in CRP; Group B (n=55): similar to Group A but enrolled in an 8 weeks hospital-based CRP and then discharged home with routine care; Group C (n=55) enrolled in an 8 weeks hospital-based CRP followed by a further 10 months of formal home-based CRP, with scheduled hospital follow-up visits. Results: Smoking resumption at 12 months was influenced by the presence of household smokers (HS): 38% of patients with HS resumed smoking compared to 27% of patients without HS (p

Published
2005
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36. Long-term effects of cardiac rehabilitation on end-exercise heart rate recovery after myocardial infarction.

Author

Giallauria F, De Lorenzo A, Pilerci F, Manakos A, Lucci R, Psaroudaki M, D'Agostino M, Del Forno D, and Vigorito C

Subjects
Female, Follow-Up Studies, Humans, Male, Middle Aged, Myocardial Infarction metabolism, Myocardial Infarction physiopathology, Oxygen Consumption physiology, Time Factors, Treatment Outcome, Exercise Therapy methods, Exercise Tolerance physiology, Heart Rate physiology, Motor Activity physiology, Myocardial Infarction rehabilitation
Abstract

Background: Heart rate recovery (HRR) is a marker of vagal tone that is a powerful predictor of mortality in patients with coronary artery disease., Design: This study aims at evaluating the effects of long-term exercise training on HRR after acute myocardial infarction (AMI), in order to clarify whether prolonged exercise training could maintain a long-term improvement of HRR., Methods: Forty-four patients after AMI were enrolled in a 3-month hospital-based exercise training programme. At the end, patients were subdivided into two groups: group A (n=22), patients discharged with a specific home-based exercise training programme and instructions for improving leisure-time physical activity; group B (n=22), patients discharged with generic instructions to maintain physical activity. All patients underwent a cardiopulmonary exercise test before, at the end of 3 months exercise training and at 6 months follow-up., Results: At the end of the hospital-based exercise training programme we observed an increase in peak oxygen consumption [VO2peak; from 13.9+/-3.6 to 18+/-2.7 ml/kg per min (A) and from 14.1+/-3.9 to 17.9+/-2.1 ml/kg per min (B), P<0.001] and in HRR [from 17.1+/-1.8 to 23.4+/-1.4 beats/min (A), and from 18.8+/-2.1 to 24.3+/-1.9 beats/min (B), P<0.001]. At 6 months' follow-up we observed a further improvement in VO2peak (from 18.0+/-2.7 to 20.3+/-2.7 ml/kg per min, P<0.001) and in HRR (from 23.4+/-1.4 to 27.8+/-2.1 beats/min, P<0.001) in group A, but a significant decrease in VO2peak and in HRR in group B (P<0.001)., Conclusion: Long-term exercise training is useful for maintaining or improving the beneficial results of the standard 3-month exercise training programme on cardiovascular capacity and HRR. This observation may bear beneficial prognostic effects on patients after AMI.

Published
2006
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37. Reduction of N terminal-pro-brain (B-type) natriuretic peptide levels with exercise-based cardiac rehabilitation in patients with left ventricular dysfunction after myocardial infarction.

Author

Giallauria F, De Lorenzo A, Pilerci F, Manakos A, Lucci R, Psaroudaki M, D'Agostino M, Del Forno D, and Vigorito C

Subjects
Biomarkers blood, Echocardiography, Doppler, Pulsed, Female, Heart Ventricles diagnostic imaging, Heart Ventricles metabolism, Heart Ventricles physiopathology, Humans, Male, Middle Aged, Myocardial Contraction physiology, Myocardial Infarction blood, Myocardial Infarction physiopathology, Treatment Outcome, Exercise physiology, Exercise Therapy methods, Myocardial Infarction complications, Natriuretic Peptide, Brain blood, Ventricular Dysfunction, Left blood, Ventricular Dysfunction, Left etiology, Ventricular Dysfunction, Left rehabilitation
Abstract

Introduction: N-terminal-pro-brain (B-type) natriuretic peptide (NT-pro-BNP) is a peptide hormone released from ventricles in response to myocyte stretch. The aim of the study was to investigate the influence of exercise training on plasma NT-pro-BNP to verify if this parameter could be used as a biological marker of left ventricular remodelling in myocardial infarction patients undergoing an exercise training programme., Methods: Forty-four patients after myocardial infarction were enrolled into a cardiac rehabilitation programme, and were randomized in two groups of 22 patients each. Group A patients followed a 3-month exercise training programme, while group B patients received only routine recommendations. All patients underwent NT-pro-BNP assay, and cardiopulmonary exercise test before hospital discharge and after 3 months., Results: In Group A, exercise training reduced NT-pro-BNP levels (from 1498+/-438 to 470+/-375 pg/ml, P=0.0026), increased maximal (VO2peak+4.3+/-2.9 ml/kg per min, P<0.001; Powermax+38+/-7, P<0.001) exercise parameters and work efficiency (Powermax/VO2peak+1.3+/-0.4 Power/ml per kg per min, P<0.001); there was also an inverse correlation between changes in NT-pro-BNP levels and in VO2peak (r=-0.72, P<0.001), E-wave (r=-0.51, P<0.001) and E/A ratio (r=0.59, P<0.001). In group B, at 3 months, no changes were observed in NT-pro-BNP levels, exercise and echocardiographic parameters., Conclusion: Three months exercise training in patients with moderate left ventricular systolic dysfunction after myocardial infarction induced a reduction in NT-pro-BNP levels, an improvement of exercise capacity and early left ventricular diastolic filling, without negative left ventricular remodelling. Whether the reduction of NT-pro-BNP levels could be useful as a surrogate marker of favourable left ventricular remodelling at a later follow-up remains to be further explored.

Published
2006
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38. Efficacy of telecardiology in improving the results of cardiac rehabilitation after acute myocardial infarction.

Author

Giallauria F, Lucci R, Pilerci F, De Lorenzo A, Manakos A, Psaroudaki M, Dagostino M, Vitelli A, Maresca L, Del Forno D, and Vigorito C

Subjects
Aged, Case-Control Studies, Exercise Test, Humans, Male, Middle Aged, Patient Compliance, Program Evaluation statistics & numerical data, Psychometrics, Quality of Life, Electrocardiography, Ambulatory methods, Home Care Services, Myocardial Infarction rehabilitation, Telemedicine
Abstract

Background: This study was addressed to verify if Telecardiology (TC) improves the results of Cardiac Rehabilitation in patients following a home-based Cardiac Rehabilitation Program (CRP) after acute myocardial infarction (AMI)., Materials and Methods: We studied three groups of patients after AMI: Group A (control group): 15 patients, who followed a standard in-hospital CRP of 3 weekly sessions of 2 months duration; Group B (study group): 15 patients, who were enrolled in a home-based CRP of similar duration and were monitored by TC with the aid of an ecg-device (Sorin Life Watch CG 6106); Group C (second control group): 15 patients, who followed a home-based CRP without ecg-monitoring by TC. All patients performed a symptom-limited exercise testing at the beginning of the CRP. Psychometric data (STAI-Y1, STAI-Y2, BDI) were also evaluated. At the end of the CRP all patients underwent repeated exercise testing and psychometric evaluation., Results: TC applied to the home-based CRP was associated with a good compliance to the program. Compared to Group C, in Group B we observed an increase of maximal heart rate, exercise duration, maximal work-load, and an improvement of anxiety, a trend to reduction of depression, and an improvement of quality of life. These results were very similar to Group A patients following a hospital-based CRP., Conclusions: TC improves compliance, functional capacity and psychological profile of patients undergoing a home-based CRP, compared to patients enrolled in a home-based CRP without ecg-monitoring by Telecardiology.

Published
2006
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39. Role of smokers in the household and of cardiac rehabilitation in smoking behaviour after acute myocardial infarction.

Author

Giallauria F, Paragliola T, Pilerci F, Del Forno D, De Lorenzo A, Manakos A, Lucci R, Psaroudaki M, D'Agostino M, and Vigorito C

Subjects
Aged, Behavior Therapy, Chi-Square Distribution, Counseling, Data Interpretation, Statistical, Exercise, Follow-Up Studies, Humans, Male, Middle Aged, Myocardial Infarction prevention & control, Nuclear Family, Patient Compliance, Rehabilitation, Risk Factors, Smoking Prevention, Time Factors, Family Characteristics, Myocardial Infarction rehabilitation, Smoking, Smoking Cessation
Abstract

Objects: This study aims to evaluate the influence of household smokers and of a prolonged, comprehensive home-based Cardiac Rehabilitation Program (CRP) on patient's long term smoking behaviour after AMI., Methods: 164 male post-AMI patients, all smokers until the day of AMI, were subdivided into three groups: Group A (n=54): patients with recent AMI, discharged from hospital without enrolment in CRP; Group B (n=55): similar to Group A but enrolled in an 8 weeks hospital-based CRP and then discharged home with routine care; Group C (n=55) enrolled in an 8 weeks hospital-based CRP followed by a further 10 months of formal home-based CRP, with scheduled hospital follow-up visits., Results: Smoking resumption at 12 months was influenced by the presence of household smokers (HS): 38% of patients with HS resumed smoking compared to 27% of patients without HS (p <0.01). Adherence to a CRP was inversely correlated to smoking resumption: there were fewer smoking patients at 12 months from AMI in Group C than in Groups A or B (11% in C vs. 29% and 55% in B and A, respectively, p <0.001)., Conclusions: Long term maintenance of CRP seems to be the best way to achieve a reduction of long term smoking habit and maintain adherence to prescription in patients after AMI. Counselling and behavioural intervention should also be extended to family members in order to maximize the benefit of secondary prevention.

Published
2005
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40. [Inflammatory syndrome after thoracic aortic endoprosthesis implantation associated with cortico-suprarenal adenoma].

Author

Giallauria F, De Lorenzo A, Manakos A, Pilerci F, Psaroudaki M, De Cristofaro A, Lucci R, Del Forno D, and Vigorito C

Subjects
Aged, Aorta, Thoracic surgery, Aortic Aneurysm, Thoracic rehabilitation, Humans, Inflammation complications, Male, Syndrome, Adenoma complications, Adrenal Gland Neoplasms complications, Aortic Aneurysm, Thoracic surgery, Blood Vessel Prosthesis adverse effects, Inflammation etiology
Abstract

We report a case of a 68-year-old patient, admitted with diagnosis of aneurysm of the descending thoracic aorta to the Department of Cardiac Surgery, where he underwent percutaneous endovascular application of 4 endoprostheses in the descending thoracic aorta. After antibiotic prophylaxis and hemodynamic stabilization, the patient was admitted to the Cardiac Rehabilitation Unit for the management of the of postoperative course and undergo a program of cardiac rehabilitation. Five days following admission and before starting physical training, the patient developed fever associated with neutrophil leukocytosis, strong activation of inflammatory markers and sideropenic anemia, compatible with post-implantation inflammatory syndrome. Significant hypokalemia also occurred. Further investigations showed left cortical-suprarenal adenoma. The inflammatory state relapsed spontaneously and the patient was discharged with indication to undergo an endocrinologic consultation.

Published
2005
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