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349 results on '"Pietropaolo, V."'

1. Development and preliminary tests of resistive microdot and microstrip detectors

Author

Fonte, P., Nappi, E., Martinengo, P., Oliveira, R., Pietropaolo, V. Peskov F., and Picchi, P.

Subjects
Physics - Instrumentation and Detectors
Abstract

In the last few years our group have focused on developing various designs of spark-protected micropattern gaseous detectors featuring resistive electrodes instead of the traditional metallic ones: resistive microstrip counters, resistive GEM, resistive MICROMEGAS. These detectors combine in one design the best features of RPCs (spark-protection) and micropattern detectors (a high position resolution). In this paper we report the progress so far made in developing other types of resistive micropattern detectors: a microdot-microhole detector and a microgap-microstrip detector. The former detector is an optimal electron amplifier for some special designs of dual phase noble liquid TPCs, for example with a CsI photocathode immersed inside the noble liquid. Preliminary tests of such a detector, for the first time built and investigated, are reported in this paper. The latter detector is mainly orientated towards medical imaging applications such as X-ray scanners. However, we believe that after a proper gas optimization, these detectors could also achieve a high time resolution and could thus be used in applications as TOF-PET, detection of charged particles with simultaneous high time and position resolution etc., Comment: Presented at the XI International RPC Workshop, Frascati, Italy, February 2012 and at RD-51 meetings at CERN in November 2011 and February 2012 and at the RD-51 Meeting at CERN, June 2012

Published
2012
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11. Diagnostic accuracy of Xpert MTB/RIF versus smear microscopy in the early diagnosis tuberculosis in the real life of 'Umberto I' Hospital Rome

Author

Ilaria Sauzullo, Rodio, D. M., Facchinetti, S., Puggioni, G., Angelis, M., Goldoni, P., Vullo, V., Mengoni, F., Trancassini, M., and Pietropaolo, V.

Subjects
Microscopy, Rome, Humans, smear microscopy, tuberculosis, xpert mtb/rif, Polymerase Chain Reaction, Sensitivity and Specificity, Tuberculosis, Pulmonary
Abstract

Early diagnosis of tuberculosis (TB) is one of the primary challenges in curtailing the spread of TB. This study aimed to determine the diagnostic accuracy of Xpert MTB/RIF for the identification of M. tuberculosis in clinical specimens, and compare this to a microscopist's diagnostic performance. Xpert MTB/ RIF was positive in all specimens with culture-confirmed TB, giving a higher sensitivity than the smear microscopy (100% versus 63%). The use of the Xpert MTB/RIF, as part of routine assay, permits rapid diagnosis of TB and enables clinicians to start an effective treatment.

Published
2016

12. Tubulointerstitial lesions in lupus nephritis: International multicentre study in a large cohort of patients with repeat biopsy

Author

PAGNI, FABIO, GALIMBERTI, STEFANIA, REBORA, PAOLA, PIERUZZI, FEDERICO UMBERTO EMILIO GUGLIE, SMITH, ANDREW JAMES, Galbiati, E, Pietropaolo, V, Ferrario, F., Pagni, F, Galimberti, S, Galbiati, E, Rebora, P, Pietropaolo, V, Pieruzzi, F, Smith, A, and Ferrario, F

Subjects
Adult, Male, Biopsy, lupus nephriti, Kidney, International Society of Nephrology/Renal Pathology Society classification, Severity of Illness Index, Young Adult, Predictive Value of Tests, Humans, ISN/RPS classification, Retrospective Studies, repeat biopsy, Chi-Square Distribution, lupus tubulointerstitial nephriti, Prognosis, Fibrosis, Lupus Nephritis, Proteinuria, Logistic Models, Multivariate Analysis, Linear Models, Nephritis, Interstitial, Female, Atrophy, Glomerular Filtration Rate
Abstract

Background The glomerulocentric International Society of Nephrology/Renal Pathology Society (ISN/RPS) classification is the gold standard for the evaluation of lupus nephritis, while tubulointerstitial (TIN) parameters are often under-recognized in pathological reports. Methods Renal biopsies from 142 patients who underwent repeat biopsy (RB) were evaluated for the following histological parameters: (i) inflammatory interstitial infiltrates; (ii) interstitial fibrosis; (iii) tubulitis; and (iv) tubular atrophy. The inter-relationships between the four TIN variables were explored by multivariate analysis. A linear mixed model was used to investigate the potential impact of TIN variables on EGFR and proteinuria at the two biopsy occasions. Results The study showed that moderate-severe lesions were not so frequent at the reference biopsy, but more extensively represented upon RB. A strong association was found between the two inflammatory indices and between those related to chronic damage, while the relationship with the ISN/RPS classification was present at RB. If class IV-G was the most related with TIN (especially at RB), the existence of primary TIN in class II patients was also confirmed. Finally, our results support the hypothesis that tubulitis is an independent predictive factor for EGFR. Conclusions We recommend that the standard histological evaluation of SLE nephritis also includes TIN features.

Published
2015

14. In vitroactivity of fosfomycin against mucoid and non-mucoid Pseudomonas aeruginosastrains

Author

Bressan, A, Rodio, DM, Stangherlin, F, Puggioni, G, Ambrosi, C, Arcari, G, Carattoli, A, Antonelli, G, Pietropaolo, V, and Trancassini, M

Abstract

•No difference observed in MIC distribution of fosfomycin between mucoid and non-mucoid strains.•MIC50 and MIC90 were 32 μg/mL and 64 μg/mL in both mucoid and non-mucoid strains respectively.•There is agreement between automated system and the reference method for the fosfomycin test.

Published
2020
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15. Tubulointerstitial lesions in lupus nephritis: International multicentre study in a large cohort of patients with repeat biopsy

Author

Pagni, F, Galimberti, S, Galbiati, E, Rebora, P, Pietropaolo, V, Pieruzzi, F, Smith, A, Ferrario, F, PAGNI, FABIO, GALIMBERTI, STEFANIA, REBORA, PAOLA, PIERUZZI, FEDERICO UMBERTO EMILIO GUGLIE, SMITH, ANDREW JAMES, Ferrario, F., Pagni, F, Galimberti, S, Galbiati, E, Rebora, P, Pietropaolo, V, Pieruzzi, F, Smith, A, Ferrario, F, PAGNI, FABIO, GALIMBERTI, STEFANIA, REBORA, PAOLA, PIERUZZI, FEDERICO UMBERTO EMILIO GUGLIE, SMITH, ANDREW JAMES, and Ferrario, F.

Abstract

Background The glomerulocentric International Society of Nephrology/Renal Pathology Society (ISN/RPS) classification is the gold standard for the evaluation of lupus nephritis, while tubulointerstitial (TIN) parameters are often under-recognized in pathological reports. Methods Renal biopsies from 142 patients who underwent repeat biopsy (RB) were evaluated for the following histological parameters: (i) inflammatory interstitial infiltrates; (ii) interstitial fibrosis; (iii) tubulitis; and (iv) tubular atrophy. The inter-relationships between the four TIN variables were explored by multivariate analysis. A linear mixed model was used to investigate the potential impact of TIN variables on EGFR and proteinuria at the two biopsy occasions. Results The study showed that moderate-severe lesions were not so frequent at the reference biopsy, but more extensively represented upon RB. A strong association was found between the two inflammatory indices and between those related to chronic damage, while the relationship with the ISN/RPS classification was present at RB. If class IV-G was the most related with TIN (especially at RB), the existence of primary TIN in class II patients was also confirmed. Finally, our results support the hypothesis that tubulitis is an independent predictive factor for EGFR. Conclusions We recommend that the standard histological evaluation of SLE nephritis also includes TIN features.

Published
2016

16. How to predict a high rate of inappropriateness for upper endoscopy in an endoscopic centre?

Author

Buri, L, Bersani, G, Hassan, C, Anti, M, Bianco, Ma, Cipolletta, L, Di Giulio, E, Di Matteo, G, Familiari, Luigi, Ficano, L, Loriga, P, Morini, S, Pietropaolo, V, Zambelli, A, Grossi, E, Intraligi, M, Tessari, F, Buscema, M, the SIED Appropriateness Working Group, Buri,L, Bersani,G, Hassan,C, Anti,M, Bianco,M, Cipolletta,L, Di Giulio,E, Di Matteo,G, Familiari,L, Ficano,L, Loriga,P, Morini,S, Pietropaolo,V, Zambelli,A, Grossi,E, Intraligi,M, Tessari,F, and Buscema,M

Subjects
Adult, Pediatrics, medicine.medical_specialty, appropriatness, Group B, Upper Gastrointestinal Tract, Age Distribution, Medicine, Humans, Appropriateness, Endoscopy, Digestive System, endoscopy, Referral and Consultation, Retrospective Studies, Ultrasonography, Settore MED/12 - Gastroenterologia, Hepatology, business.industry, Patient Selection, Upper endoscopy, upper endoscopy, Gastroenterology, Retrospective cohort study, Stepwise regression, Middle Aged, Appropriateness Upper endoscopy, Settore MED/18 - Chirurgia Generale, Italy, ROC Curve, Practice Guidelines as Topic, Age distribution, business
Abstract

BACKGROUND: Inappropriateness of upper endoscopy (EGD) indication causes decreased diagnostic yield. Our aim of was to identify predictors of appropriateness rate for EGD among endoscopic centres. METHODS: A post-hoc analysis of two multicentre cross-sectional studies, including 6270 and 8252 patients consecutively referred to EGD in 44 (group A) and 55 (group B) endoscopic Italian centres in 2003 and 2007, respectively, was performed. A multiple forward stepwise regression was applied to group A, and independently validated in group B. A

Published
2010

26. Upper GI endoscopy in elderly patients: predictive factors of relevant endoscopic findings

Author

Buri, L, Zullo, A, Hassan, Cesare, Bersani, Giuseppe, Anti, Marcello, Bianco, Marco, Cipolletta, L, Giulio, Ed, Matteo, Gd, Familiari, L, Ficano, L, Loriga, P, Morini, S, Pietropaolo, V, Zambelli, A, Grossi, Eugenia, Tessari, F, Intraligi, M, Buscema, M., Buri, L, Zullo, A, Hassan, Cesare, Bersani, Giuseppe, Anti, Marcello, Bianco, Marco, Cipolletta, L, Giulio, Ed, Matteo, Gd, Familiari, L, Ficano, L, Loriga, P, Morini, S, Pietropaolo, V, Zambelli, A, Grossi, Eugenia, Tessari, F, Intraligi, M, and Buscema, M.

Abstract

Elderly patients are at increased risk for peptic ulcer and cancer. Predictive factors of relevant endoscopic findings at upper endoscopy in the elderly are unknown. This was a post hoc analysis of a nationwide, endoscopic study. A total of 3,147 elderly patients were selected. Demographic, clinical, and endoscopic data were systematically collected. Relevant findings and new diagnoses of peptic ulcer and malignancy were computed. Both univariate and multivariate analyses were performed. A total of 1,559 (49.5%), 213 (6.8%), 93 (3%) relevant findings, peptic ulcers, and malignancies were detected. Peptic ulcers and malignancies were more frequent in >85-year-old patients (OR 3.1, 95% CI = 2.0-4.7, p = 0.001). The presence of dysphagia (OR = 5.15), weight loss (OR = 4.77), persistent vomiting (OR = 3.68), anaemia (OR = 1.83), and male gender (OR = 1.9) were significantly associated with a malignancy, whilst overt bleeding (OR = 6.66), NSAIDs use (OR = 2.23), and epigastric pain (OR = 1.90) were associated with the presence of peptic ulcer. Peptic ulcer or malignancies were detected in 10% of elderly patients, supporting the use of endoscopy in this age group. Very elderly patients appear to be at higher risk of such lesions.

Published
2011

27. Ileal intubation with a transnasal endoscope

Author

Pietropaolo, V, Hassan, Cesare, Pontone, S, Onorato, Maria Giovanna, Pedretti, Giorgio, Zullo, A., Pietropaolo, V, Hassan, Cesare, Pontone, S, Onorato, Maria Giovanna, Pedretti, Giorgio, and Zullo, A.

Abstract

Transnasal upper endoscopy has been implemented in the last decade as it is perceived as less fastidious than peroral endoscopy, and small-caliber gastroscopes are widely available in the endoscopic centres. We report the feasibility of performing a full colonic study with ileal intubation, using a small-caliber endoscope commonly used for transanal endoscopy, after failing with a standard gastroscope.

Published
2010

28. Appropriateness guidelines and predictive rules to select patients for upper endoscopy: a nationwide multicenter study

Author

Buri, L, Hassan, Cesare, Bersani, Giuseppe, Anti, Marcello, Bianco, Marco, Cipolletta, L, Di Giulio, E, Di Matteo, G, Familiari, L, Ficano, L, Loriga, P, Morini, S, Pietropaolo, V, Zambelli, A, Grossi, Eugenia, Intraligi, M, Buscema, M., Buri, L, Hassan, Cesare, Bersani, Giuseppe, Anti, Marcello, Bianco, Marco, Cipolletta, L, Di Giulio, E, Di Matteo, G, Familiari, L, Ficano, L, Loriga, P, Morini, S, Pietropaolo, V, Zambelli, A, Grossi, Eugenia, Intraligi, M, and Buscema, M.

Abstract

Selecting patients appropriately for upper endoscopy (EGD) is crucial for efficient use of endoscopy. The objective of this study was to compare different clinical strategies and statistical methods to select patients for EGD, namely appropriateness guidelines, age and/or alarm features, and multivariate and artificial neural network (ANN) models.

Published
2010

29. Appropriateness of upper-GI endoscopy: an Italian survey on behalf of the Italian Society of Digestive Endoscopy

Author

Hassan, Cesare, Bersani, Giuseppe, Buri, L, Zullo, A, Anti, Marcello, Bianco, Marco, Di Giulio, E, Ficano, L, Morini, S, Di Matteo, G, Loriga, P, Pietropaolo, V, Cipolletta, L, Costamagna, Guido, Costamagna, Guido (ORCID:0000-0002-8100-2731), Hassan, Cesare, Bersani, Giuseppe, Buri, L, Zullo, A, Anti, Marcello, Bianco, Marco, Di Giulio, E, Ficano, L, Morini, S, Di Matteo, G, Loriga, P, Pietropaolo, V, Cipolletta, L, Costamagna, Guido, and Costamagna, Guido (ORCID:0000-0002-8100-2731)

Abstract

Open-access endoscopy allows physicians to directly schedule endoscopic procedures for their patients without prior consultation. An evaluation of both appropriateness and diagnostic yield of endoscopic procedures is critical when assessing the costs and benefits of endoscopy in an open-access setting. The aim of this Italian multicenter study was to assess the appropriate use of upper endoscopy (EGD) in an open-access system and to establish the yield of diagnostic information relevant to patient care.

Published
2007

30. Detection of JC and BK viral genome in specimens of HIV-1 infected subjects

Author

Degener, A. M., Pietropaolo, V., Di Taranto, C., Rizzuti, V., Ameglio, F., Cordiali Fei, P., Caprilli, F., Bruno Capitanio, Sinibaldi, L., and Orsi, N.

Subjects
Adult, Male, Sexual Behavior, Papillomavirus Infections, HIV Infections, Homosexuality, Middle Aged, Viral Load, JC Virus, Polymerase Chain Reaction, bkv, hiv-1, hiv-positive subjects, human polyomaviruses jc and bk, jcv, pbmc, pcr, urine, CD4 Lymphocyte Count, Virus Latency, Capsid, BK Virus, DNA, Viral, HIV-1, Leukocytes, Mononuclear, Humans, Capsid Proteins, Female, Substance Abuse, Intravenous, Polymorphism, Restriction Fragment Length
Abstract

Human polyomaviruses JC and BK are ubiquitous in healthy human adults, persist as latent viruses and can be reactivated in the immunodeficient host giving different pathologies. Due to the experimental evidence of their potential oncogenicity and neurotropism, as well as to the enhanced viral production induced by co-infection with HIV-1, a possible role of these polyomaviruses has been suggested in AIDS-associated progressive multifocal leucoencephalopathy (PML) and Kaposi's sarcoma. JCV and BKV DNA was detected by PCR in urine and in peripheral blood mononuclear cells (PBMC) using primers specific for structural (VP1) and regulatory (R) regions. In HIV-positive subjects BKV and JCV sequences were found respectively in 8.1% and 31.6% of urine samples whereas in PBMC the positivity increased to 22.8% for JCV and in 51.1% for BKV. Our results indicated that, at DNA level, the presence of BKV and JCV in urine and PBMC was higher in HIV-1 positive subjects than in HIV-1 negative subjects and that, in contrast with JCV, BKV positivity was inversely related to blood CD4-level. Intravenous drug users (IVDU) showed significant increases in both BKV and JCV positivity, while an increased JCV viruria was found in homo-bisexuals compared to heterosexuals. The high prevalence of viral DNA in PBMC of both healthy and HIV-positive individuals agrees with the hypothesis that lymphocytes may represent a viral latency site permitting the establishment of virus persistence in affected organs, or a vehicle for the spread of the infection to different tissues.

Published
1997

32. Polyomavirus BK Infection Before Liver Transplantation in Patients With Chronic Kidney Disease

Author

Mitterhofer, A.P., primary, Tinti, F., additional, Umbro, I., additional, Pietropaolo, V., additional, Fiacco, F., additional, Bellizzi, A., additional, Anzivino, E., additional, Ginanni Corradini, S., additional, Poli, L., additional, Rossi, M., additional, Berloco, P.B., additional, Ferretti, G., additional, Chiarini, F., additional, and Taliani, G., additional

Published
2012
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33. Polyomavirus BK Infection in End-stage Renal Disease: Analysis of Viral Replication in Patients on Hemodialysis or Peritoneal Dialysis

Author

Mitterhofer, A.P., primary, Umbro, I., additional, Pietropaolo, V., additional, Meçule, A., additional, Russo, G.E., additional, Tinti, F., additional, Fiacco, F., additional, Poli, L., additional, Bellizzi, A., additional, Anzivino, E., additional, Ferretti, G., additional, Berloco, P.B., additional, Chiarini, F., additional, and Taliani, G., additional

Published
2012
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35. Antibacterial Activity of Methyl Aminolevulinate Photodynamic Therapy in the Treatment of a Cutaneous Ulcer

Author

Devirgiliis, V., primary, Panasiti, V., additional, Fioriti, D., additional, Anzivino, E., additional, Bellizzi, A., additional, Cimillo, M., additional, Curzio, M., additional, Melis, L., additional, Roberti, V., additional, Gobbi, S., additional, Lieto, P., additional, Richetta, A.G., additional, Calvieri, S., additional, Chiarini, F., additional, Nicosia, R., additional, and Pietropaolo, V., additional

Published
2011
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40. JC Viral Reactivation in a Pediatric Patient with Crohn's Disease

Author

Bellizzi, A., primary, Barucca, V., additional, Di Nardo, G., additional, Fioriti, F., additional, Iebba, V., additional, Schippa, S., additional, Conte, M.P., additional, Checchi, M. Proietti, additional, Colosimo, M.T., additional, Cucchiara, S., additional, Oliva, S., additional, Chiarini, F., additional, and Pietropaolo, V., additional

Published
2010
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41. PRE-TRANSPLANT BK-VIRUS INFECTION IN DIALYZED RENAL TRANSPLANT CANDIDATES

Author

Tinti, F., primary, Mitterhofer, A. P., additional, Pietropaolo, V., additional, Barile, M., additional, Fioriti, D., additional, Mischitelli, M., additional, Limonta, A., additional, Meçule, A., additional, Ferretti, G., additional, Poli, L., additional, Chiarini, F., additional, Berloco, P., additional, and Taliani, G., additional

Published
2010
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42. Meaning of Early Polyomavirus-BK Replication Post Kidney Transplant

Author

Mitterhofer, A.P., primary, Pietropaolo, V., additional, Barile, M., additional, Tinti, F., additional, Fioriti, D., additional, Mischitelli, M., additional, Limonta, A., additional, Meçule, A., additional, Ferretti, G., additional, Poli, L., additional, Chiarini, F., additional, Berloco, P.B., additional, and Taliani, G., additional

Published
2010
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43. OC.11.1 PREDICTIVE FACTORS OF RELEVANT ENDOSCOPIC FINDINGS IN PATIENTS WITH A REGULAR USE OF NSAIDS

Author

Buri, L., primary, Hassan, C., additional, Bersani, G., additional, Anti, M., additional, Bianco, M., additional, Cipolletta, L., additional, Di Giulio, E., additional, Di Matteo, G., additional, Familiari, L., additional, Ficano, L., additional, Loriga, P., additional, Morini, S., additional, Pietropaolo, V., additional, Zambelli, A., additional, Grossi, E., additional, Tessari, F., additional, Intraligi, M., additional, and Buscema, M., additional

Published
2010
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44. P.170 PREDICTIVE RULES TO SELECT UNINVESTIGATED AND UNCOMPLICATED DYSPEPTIC PATIENTS FOR UPPER ENDOSCOPY

Author

Buri, L., primary, Hassan, C., additional, Bersani, G., additional, Anti, M., additional, Bianco, M., additional, Cipolletta, L., additional, Di Giulio, E., additional, DiMatteo, G., additional, Familiari, L., additional, Ficano, L., additional, Loriga, P., additional, Morini, S., additional, Pietropaolo, V., additional, Zambelli, A., additional, Grossi, E., additional, Intraligi, M., additional, and Buscema, M., additional

Published
2010
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45. P.169 PREDICTIVE FACTORS OF RELEVANT ENDOSCOPIC FINDINGS IN ELDERLY PATIENTS AT UPPER ENDOSCOPY

Author

Buri, L., primary, Hassan, C., additional, Bersani, G., additional, Anti, M., additional, Bianco, M., additional, Cipolletta, L., additional, Di Giulio, E., additional, Di Matteo, G., additional, Familiari, L., additional, Ficano, L., additional, Loriga, P., additional, Morini, S., additional, Pietropaolo, V., additional, Zambelli, A., additional, Grossi, E., additional, Tessari, F., additional, Intraligi, M., additional, and Buscema, M., additional

Published
2010
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48. Bromhidrosis Induced by Sphingomonas Paucimobilis: A Case Report

Author

Mancini, M., primary, Panasiti, V., additional, Devirgiliis, V., additional, Pietropaolo, V., additional, Fioriti, D, additional, Nicosia, R., additional, Curzio, M., additional, Roberti, V., additional, Gobbi, S., additional, Bottoni, U., additional, Chiarini, F., additional, and Calvieri, S., additional

Published
2009
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50. APPROPRIATENESS GUIDELINES AND PREDICTIVE RULES TO SELECT PATIENTS FOR UPPER ENDOSCOPY: A NATIONWIDE, MULTICENTER STUDY ON BEHALF OF THE ITALIAN SOCIETY OF DIGESTIVE ENDOSCOPY (SIED)

Author

Buri, L., primary, Bersani, G., additional, Hassan, C., additional, Anti, M., additional, Bianco, M.A., additional, Cipolletta, L., additional, Di Giulio, E., additional, Di Matteo, G., additional, Familiari, L., additional, Ficano, L., additional, Loriga, P., additional, Morini, S., additional, Pietropaolo, V., additional, and Zambelli, A., additional

Published
2009
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