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3 results on '"Pietro, Cefali"'

1. Regional Survey in Lombardy, Northern Italy, on Vascular Surgery Intervention Outcomes During The COVID-19 Pandemic

Author

Raffaello Bellosta, Gabriele Piffaretti, Stefano Bonardelli, Patrizio Castelli, Roberto Chiesa, Dalmazio Frigerio, Gaetano Lanza, Stefano Pirrelli, Giovanni Rossi, Santi Trimarchi, Franco Briolini, Pietro Cefali, Roberto Caronno, Aldo Arzini, Domenico Diaco, Vittorio Baratta, Stefano Aiello, Alessandro C.L. Molinari, Francesca Giovannini, Anna Maria Socrate, Matteo Ferraris, Antonino Silvestro, Gianluca Canu, Emidio Costantini, Davide Logaldo, Federico Romani, Alfredo Lista, Cristina Busoni, Marco Setti, Roberto Mezzetti, Piergiorgio Sala, Luca Bassi, Luca Luzzani, Matteo A. Pegorer, Luca Attisani, Claudio Carugati, Monica Vescovi, Piero Trabattoni, Stefano Zoli, Andrea Rignano, Clara Magri, Pierluigi Vandone, Sergio Losa, Efrem Civilini, Giovanni Nano, Daniela Mazzaccaro, Valerio Tolva, Jessica Lanza, Ruggiero Curci, Giovanna Simonetti, Chiara Lomazzi, Viviana Grassi, Daniele Bissacco, Andrea Kahlberg, Daniele Mascia, Raffaello Dallatana, Michele Carmo, Franco Ragni, Enrico M. Marone, Antonio Bozzani, Matteo Tozzi, Marco Franchin, Gianluca Lussardi, Vittorio Segramora, Gaetano Deleo, Matteo Crippa, Tiziano Porretta, Marco Viani, Silvia Stegher, Davide Foresti, Giovanni Bonalumi, Bellosta, R., Piffaretti, G., Bonardelli, S., Castelli, P., Chiesa, R., Frigerio, D., Lanza, G., Pirrelli, S., Rossi, G., Trimarchi, S., Briolini, F., Cefali, P., Caronno, R., Arzini, A., Diaco, D., Baratta, V., Aiello, S., Molinari, A. C. L., Giovannini, F., Socrate, A. M., Ferraris, M., Silvestro, A., Canu, G., Costantini, E., Logaldo, D., Romani, F., Lista, A., Busoni, C., Setti, M., Mezzetti, R., Sala, P., Bassi, L., Luzzani, L., Pegorer, M. A., Attisani, L., Carugati, C., Vescovi, M., Trabattoni, P., Zoli, S., Rignano, A., Magri, C., Vandone, P., Losa, S., Civilini, E., Nano, G., Mazzaccaro, D., Tolva, V., Lanza, J., Curci, R., Simonetti, G., Lomazzi, C., Grassi, V., Bissacco, D., Kahlberg, A., Mascia, D., Dallatana, R., Carmo, M., Ragni, F., Marone, E. M., Bozzani, A., Tozzi, M., Franchin, M., Lussardi, G., Segramora, V., Deleo, G., Crippa, M., Porretta, T., Viani, M., Stegher, S., Foresti, D., and Bonalumi, G.

Subjects
Male, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), COVID-19, acute limb ischaemia, vascular surgery activities, Cohort Studies, Postoperative Complications, Intervention (counseling), Pandemic, Humans, Medicine, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Outbreak, Middle Aged, Vascular surgery, Northern italy, Treatment Outcome, Italy, Health Care Surveys, Emergency medicine, Female, Surgery, Cardiology and Cardiovascular Medicine, business, Complication, Vascular Surgical Procedures, Cohort study
Abstract

Objective: The characteristics and outcomes of patients undergoing vascular surgery hospitalised and managed in Lombardy are described with a comparison of patients tested positive for COVID-19 (CV19-pos) vs. those tested negative (CV19-neg). Methods: This was a multicentre, retrospective, observational cohort study which involved all vascular surgery services in Lombardy, Northern Italy. Data were retrospectively merged into a combined dataset covering the nine weeks of the Italian COVID-19 pandemic phase 1 (8 March 2020 to 3 May 2020). The primary outcome was freedom from in hospital death, secondary outcomes were re-thrombosis rate after peripheral revascularisation, and freedom from post-operative complication. Results: Among 674 patients managed during the outbreak, 659 (97.8%) were included in the final analysis: 121 (18.4%) were CV19-pos. CV19-pos status was associated with a higher rate of complications (OR 4.5; p < .001, 95% CI 2.64 – 7.84), and a higher rate of re-thrombosis after peripheral arterial revascularisation (OR 2.2; p = .004, 95% CI 1.29 – 3.88). In hospital mortality was higher in CV19-pos patients (24.8% vs. 5.6%; OR 5.4, p < .001;95% CI 2.86 – 8.92). Binary logistic regression analysis identified CV19-pos status (OR 7.6; p < .001, 95% CI 3.75 – 15.28) and age > 80 years (OR 3.2; p = .001, 95% CI 1.61 – 6.57) to be predictors of in hospital death. Conclusion: In this experience of the vascular surgery group of Lombardy, COVID-19 infection was a marker of poor outcomes in terms of mortality and post-operative complications for patients undergoing vascular surgery treatments.

Published
2021
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2. Differences in hub and spoke vascular units practice during the novel Coronavirus-19 (COVID-19) outbreak in Lombardy, Italy

Author

Bellosta, Raffaello, Bissacco, Daniele, Rossi, Giovanni, Pirrelli, Stefano, Lanza, Gaetano, Frigerio, Dalmazio, Chiesa, Roberto, Castelli, Patrizio, Bonardelli, Stefano, Trimarchi, Santi, Stefano Aiello, Aldo Arzini, Luca Attisani, Vittorio Baratta, Luca Bassi, Giovanni Bonalumi, Antonio Bozzani, Franco Briolini, Cristina Busoni, Gianluca Canu, Michele Carmo, Roberto Caronno, Claudio Carugati, Pietro Cefali, Efrem Civilini, Emidio Costantini, Matteo Crippa, Ruggiero Curci, Raffaello Dallatana, Gaetano Deleo, Domenico Diaco, Matteo Ferraris, Davide Foresti, Marco Franchin, Francesca Giovannini, Viviana Grassi, Andrea Kahlberg, Jessica Lanza, Davide Logaldo, Chiara Lomazzi, Sergio Losa, Alfredo Lista, Gianluca Lussardi, Luca Luzzani, Clara Magri, Enrico M Marone, Daniele Mascia, Daniela Mazzaccaro, Roberto Mezzetti, Alessandro C Molinari, Giovanni Nano, Matteo A Pegorer, Gabriele Piffaretti, Tiziano Porretta, Franco Ragni, Andrea Rignano, Federico Romani, Piergiorgio Sala, Vittorio Segramora, Marco Setti, Antonino Silvestro, Giovanna Simonetti, Anna M Socrate, Silvia Stegher, Valerio Tolva, Matteo Tozzi, Piero Trabattoni, Pierluigi Vandone, Monica Vescovi, Marco Viani, Stefano Zoli, Bellosta, Raffaello, Bissacco, Daniele, Rossi, Giovanni, Pirrelli, Stefano, Lanza, Gaetano, Frigerio, Dalmazio, Chiesa, Roberto, Castelli, Patrizio, Bonardelli, Stefano, Trimarchi, Santi, Stefano, Aiello, Aldo, Arzini, Luca, Attisani, Vittorio, Baratta, Luca, Bassi, Giovanni, Bonalumi, Antonio, Bozzani, Franco, Briolini, Cristina, Busoni, Gianluca, Canu, Michele, Carmo, Roberto, Caronno, Claudio, Carugati, Pietro, Cefali, Efrem, Civilini, Emidio, Costantini, Matteo, Crippa, Ruggiero, Curci, Raffaello, Dallatana, Gaetano, Deleo, Domenico, Diaco, Matteo, Ferrari, Davide, Foresti, Marco, Franchin, Francesca, Giovannini, Viviana, Grassi, Kahlberg, ANDREA LUITZ, Jessica, Lanza, Davide, Logaldo, Chiara, Lomazzi, Sergio, Losa, Alfredo, Lista, Gianluca, Lussardi, Luca, Luzzani, Clara, Magri, Enrico, M Marone, Daniele, Mascia, Daniela, Mazzaccaro, Roberto, Mezzetti, Alessandro, C Molinari, Giovanni, Nano, Matteo, A Pegorer, Gabriele, Piffaretti, Tiziano, Porretta, Franco, Ragni, Andrea, Rignano, Federico, Romani, Piergiorgio, Sala, Vittorio, Segramora, Marco, Setti, Antonino, Silvestro, Giovanna, Simonetti, Anna, M Socrate, Silvia, Stegher, Valerio, Tolva, Matteo, Tozzi, Piero, Trabattoni, Pierluigi, Vandone, Monica, Vescovi, Marco, Viani, and Stefano, Zoli

Subjects
Adult, Male, medicine.medical_specialty, Multivariate analysis, medicine.medical_treatment, Pneumonia, Viral, COVID-19, Vascular surgical procedures, Multicenter registry, Emergencies, Disease, Vascular surgery, Vascular emergencies, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Clinical endpoint, Humans, Registries, Vascular Diseases, Pandemics, Referral and Consultation, Aged, Retrospective Studies, business.industry, Vascular disease, SARS-CoV-2, Mortality rate, General Medicine, Middle Aged, medicine.disease, Hospitalization, Pneumonia, 030228 respiratory system, Amputation, Italy, Surgery, Female, Cardiology and Cardiovascular Medicine, business
Abstract

BACKGROUND: To highlight clinical practice among referral (Hub, HH) or satellite (Spoke, SH) hospitals Vascular Surgery Units (VSUs) in Lombardy, during the COVID-19 pandemic "phase 1" period (March 8 - May 3, 2020). METHODS: The Vascular Surgery Group of Regione Lombardia Register, a real-word, multicenter, retrospective register was interrogated. All patients admitted with vascular disease were included. Patients' data on demographics, COVID-19 positivity, comorbidities and outcomes were extrapolated. Two cohorts were obtained: patients admitted to HH or SH. Primary endpoint was 30- day mortality rate. Secondary outcomes were 30-day complications and amputation (in case of peripheral artery disease [PAD]) rates. Univariate and multivariate analysis were used to compare HH and SH groups and predictors of poor outcomes. RESULTS: During the study period, 659 vascular patients in 4 HH and 27 SH were analyzed. Among these, 321 (48.7%) were admitted to a HH. No difference in COVID-19 positive patients was described (21.7% in HH vs 15.9% in SH; p=.058). After 30 days from intervention, HH and SH experienced similar mortality and no-intervention-related complication rate (12.1% vs 10.0%; p=.427 and 10.3% vs 8.3%; p=.377, respectively). Conversely, in HH postoperative complications were higher (23.4% vs 16.9%, p=.038) and amputations in patients treated for PAD were lower (10.8% vs 26.8%; p

Published
2020

3. Heavy metal tolerance and polychlorinated biphenyl oxidation in bacterial communities inhabiting the Pasvik River and the Varanger Fjord area (Arctic Norway)

Author

C. Abete, Stefania Giannarelli, Maria Papale, Emilio De Domenico, Luigi Michaud, Antonella Conte, Angelina Lo Giudice, Massimo Onor, Carmen Rizzo, Alessandro Ciro Rappazzo, and Pietro Cefali

Subjects
0106 biological sciences, Pollution, Geologic Sediments, media_common.quotation_subject, Fjord, bphA gene, 010501 environmental sciences, Aquatic Science, Oceanography, 01 natural sciences, Polychlorinated biphenyl, chemistry.chemical_compound, Arctic, Bioremediation, Rivers, Polychlorinated biphenyls, Metals, Heavy, Heavy metals, Polychlorinated biphenyls, Arctic, Multitolerance, bphA gene, Seawater, 0105 earth and related environmental sciences, media_common, Trophic level, geography, Heavy metals, Polychlorinated biphenyl, Arctic, Multitolerance, bphA gene, geography.geographical_feature_category, Bacteria, Arctic Regions, Norway, 010604 marine biology & hydrobiology, Biota, Contamination, Biodegradation, Environmental, Multitolerance, Heavy metals, chemistry, Environmental chemistry, Environmental science, Estuaries, Oxidation-Reduction, Water Pollutants, Chemical
Abstract

Heavy metals (HMs) and polychlorobiphenyls (PCBs) enter the Arctic environment through a variety of anthropogenic sources with deleterious effects towards biota and public health. Bacteria first transfer toxic compounds to higher trophic levels and, due to the tight link existing between prokaryotic community functions and the type and concentration of contaminants, they may be useful indicator of pollution events and potential toxicity to other forms of life. The occurrence and abundance of HM-tolerant and PCB-oxidizing bacteria in the sub-Arctic Pasvik river area, heavily impacted by anthropogenic modifications, was related to HM and PCB contamination. This latter more likely derived from local inputs rather than a global contamination with higher PCB and HM amounts (and higher bacterial viable counts) that were determined in inner and middle sections of the River. Finally, a panel of bacteria with potential applications in the bioremediation of cold environments were selected and phylogenetically identified.

Published
2019
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