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Purpose To examine the updated evidence on safety, effectiveness, and outcomes of the totally extraperitoneal (TEP) versus the laparoscopic transabdominal preperitoneal (TAPP) repair and to explore the timely tendency variations favoring one treatment over another. Methods Systematic review and trial sequential analysis (TSA) of randomized controlled trials (RCTs). MEDLINE, Scopus, Web of Science, Cochrane Central Library, and ClinicalTrials.gov were consulted. Risk Ratio (RR), weighted mean difference (WMD), and 95% confidence intervals (CI) were used as pooled effect size measures. Results Fifteen RCTs were included (1359 patients). Of these, 702 (51.6%) underwent TAPP and 657 (48.4%) TEP repair. The age of the patients ranged from 18 to 92 years and 87.9% were males. The estimated pooled RR for hernia recurrence (RR = 0.83; 95% CI 0.35–1.96) and chronic pain (RR = 1.51; 95% CI 0.54–4.22) were similar for TEP vs. TAPP. The TSA shows a cumulative z-curve without crossing the monitoring boundaries line (Z = 1.96), thus supporting true negative results while the information size was calculated as adequate for both outcomes. No significant differences were found in term of early postoperative pain, operative time, wound-related complications, hospital length of stay, return to work/daily activities, and costs. Conclusions TEP and TAPP repair seems comparable in terms of postoperative hernia recurrence and chronic pain. The cumulative evidence and information size are sufficient to provide a conclusive evidence on recurrence and chronic pain. Similar trials or meta-analyses seem unlikely to show diverse results and should be discouraged.

Different methods have been described for laparoscopic hiatoplasty and hiatus hernia (HH) repair. All techniques are not standardized and the choice to reinforce or not the hiatus with a mesh is left to the operating surgeon's preference. Hiatal surface area (HSA) has been described as an attempt at standardization; in case the area is4 cmThe aim of this study was to describe a new patient-tailored algorithm (PTA), compare its performance in predicting crura mesh buttressing to HSA, and analyze outcomes.Retrospective, single-center, descriptive study (September 2018-September 2021). Adult patients (≥ 18 years old) who underwent laparoscopic HH repair. Outcomes and quality of life measured with the disease-specific gastroesophageal reflux disease health-related quality of life (GERD-HRQL) and reflux symptom index (RSI) were analyzed.Fifty patients that underwent laparoscopic hiatoplasty and Toupet fundoplication were included. The median age was 61 years (range 32-83) and the median BMI was 26.7 (range 17-36). According to the PTA, 27 patients (54%) underwent simple suture repair while crural mesh buttressing with Phasix-ST® was used in 23 (46%). According to the HSA, the median hiatus area was 4.7 cmThe application of PTA for cruroplasty standardization in the setting of HH repair seems effective. While concordance with HSA is high, the PTA seems easier and promptly available in the operative theater with a potential increase in procedure standardization, reproducibility, and teaching.

To examine the updated evidence on safety, effectiveness, and outcomes of mesh versus suture elective umbilical hernia (UH) repair and to explore the timely tendency variations favouring one treatment over another. MEDLINE and CENTRAL databases were consulted. A systematic review, pairwise meta-analysis, and trial sequential analysis (TSA) were conducted. Six RCTs were included for a total of 742 patients. Overall, 383 (51.6%) underwent mesh, while 359 (48.4%) underwent suture repair. The estimated pooled postoperative recurrence RR was 0.27 (95% CI 0.13–0.53; p

To examine the current evidence on the therapeutic role and outcomes of robotic Transabdominal Preperitoneal Inguinal hernia repair (rTAPP) to better define its risk–benefit ratio and guide clinical decision-making. PubMed, EMBASE, and Web of Science were consulted. A Frequentist single-arm study-level random effect meta-analysis was performed. Twelve studies published between 2015 and 2018 met the inclusion criteria (1645 patients). Patients’ age ranged from 16 to 96, the BMI ranged from 19 to 35.6 kg/m2, and 86.1% were males. Unilateral hernia repair was performed in 69.6% while bilateral hernia repair was performed in 30.4% of patients. The operations were all conducted using the da Vinci Xi or Si robotic system (Intuitive Surgical, Inc., Sunnyvale, CA, USA). The rTAPP was successfully completed in 99.4% of patients and the operative time ranged from 45 to 180.4 min. The postoperative follow-up ranged from 16 to 368 days. The estimated pooled prevalence of intraoperative complications and conversion were 0.03% (95% CI 0.00–0.3) and 0.14% (95% CI 0.0–0.5%), respectively. The estimated pooled prevalence of urinary retention, seroma/hematoma, and overall complications were 3.5% (95% CI 1.6–5.8%), 4.1% (95% CI 1.6–7.5%), and 7.4% (95% CI 3.4–10.9%). The estimated pooled prevalence of hernia recurrence was 0.18% (95% CI 0.00–0.84%). Robotic technology has been progressively entering surgical thinking and gradually changing surgical procedures. Based on the results of the present study, the rTAPP seems feasible, safe, and effective in the short term for patients with unilateral and bilateral inguinal hernias. Further prospective studies and randomized controlled trials are needed to validate these findings.

BACKGROUND Despite the advent of innovative surgical platforms and operative techniques, a definitive indication of the best surgical option for the treatment of unilateral primary inguinal hernia remains unsettled. Purpose was to perform an updated and comprehensive evaluation within the major approaches to inguinal hernia. METHODS Systematic review and network meta-analyses of randomized controlled trials (RCTs) compare Lichtenstein tension-free repair, laparoscopic transabdominal preperitoneal (TAPP) repair, and totally extraperitoneal repair (TEP). Risk ratio (RR) and weighted mean difference (WMD) were used as pooled effect size measures, whereas 95% credible intervals (CrI) were used to assess relative inference. RESULTS Thirty-five RCTs (7777 patients) were included. Overall, 3496 (44.9%) underwent Lichtenstein, 1269 (16.3%) TAPP, and 3012 (38.8%) TEP repair. The Visual Analogue Scale (VAS) was significantly lower for minimally invasive repair at

Hernia recurrence after laparoscopic repair is a perplexing problem. In an effort to reduce anatomical and clinical recurrences, different type of meshes have been used to bolster the esophageal hiatus. The aim of this study was to assess safety, medium-term efficacy, and quality of life improvement after laparoscopic repair of hiatal hernia reinforced with a biosynthetic absorbable mesh (Phasix-ST®). Observational single-center retrospective single-arm cohort study (November 2015–February 2021). We included all adult patients (> 18 years old) who underwent laparoscopic paraesophageal hernia repair with Phasix-ST® mesh and Toupet fundoplication. Sixty-eight patients were included. The median postoperative stay was 3.2 days (range 2–9) and the postoperative complication rate was 11.7%. The median follow-up time was 27 months (range 1–53). No mesh-related complications were detected. Hernia recurrence was diagnosed in six patients (8.8%). The recurrence-free probability at 34 months was 0.89 (95% CI 0.807–0.988) while at 60 months was 0.86 (95% CI 0.76–0.97). Hernia recurrences were mostly observed between 21 and 36 months after the operation. None of the patients required surgical revision and all were managed with PPI. Postoperative dysphagia requiring endoscopic balloon dilatation occurred in 2.9% of patients. Compared to baseline, both the GERD-HRQL (15.2 ± 6.2 vs. 3.2 ± 3.1; p = 0.026) and all SF-36 items were significantly improved (p

Open anterior repair for inguinal hernia offers several distinct advantages over endoscopic repair, especially when real-world effectiveness is taken into account. The learning curve for endoscopic techniques is long, whereas the Lichtenstein and other open tension-free techniques are easier to teach and replicate at all levels. The outcomes of Lichtenstein repairs for primary inguinal hernia as performed by non-experts and supervised residents are comparable to those of experts. Moreover, open tension-free repair does not require expensive instruments or dedicated equipment, other than the prosthetic mesh. As such, it is feasible in any operating room anywhere in the world with limited costs. In our opinion, the most important advantage offered by open tension-free repair is that it can be performed under local anesthesia. Nevertheless, local anesthesia has some disadvantages: it requires training, excellent knowledge of the anatomy and the necessary technique, patience, and gentle handling of the tissues. Open inguinal hernia repair is a procedure that every surgeon should know and be able to perform because it is necessary to treat two conditions, groin hernia recurrence after a posterior approach (both laparoscopic and open) and pubic inguinal pain syndrome.

In modern abdominal wall hernia surgery, the achievement of the most effective tailored repair for each specific defect with the less possible invasiveness, the quicker recovery, the lower costs and the fewer risk of local occurrences, recurrences and chronic pain is the most desirable and cutting-edge goal. Since 1989 about 4219 primary unilateral not complicated inguinal hernias have been treated with specific indications with a sutureless and minimally invasive anterior open approach. The great majority of these procedures were performed under local anaesthesia in a day surgery regimen, with a systematic and careful nerve sparing, preservation of cremasteric muscle, and with a 3–5 cm skin incision. The minimally invasive sutureless nerve sparing open approach has shown a very low rate of seromas (0.45%), haematomas (0.24%) and infections (0.07%) while the width of skin incision challenges even laparoscopy. A significant reduction of both postoperative pain (2.7%) and chronic neuralgia (0.047%) has led to excellent outcomes in patients, also in terms of quality of life. Compared to the Lichtenstein’s tension-free technique, which is at now the gold standard open treatment for primary inguinal hernia worldwide, there are no significant differences in the observed recurrence rate (well below 1%). In our experience of almost 30 years we have been able to experiment and refine more and more the sutureless technique proposed by Trabucco for the treatment of primitive inguinal hernia, peer to peer, improving the local anaesthesia and the ability to detect hidden defects during the repair (Spigelian included), reducing the width of the incisions and tractions on the tissues, introducing the concept of a gentle and bloodless “finger surgery” according to a minimally invasive, extremely anatomic, safe, inexpensive, very effective anterior open approach.

The abdominal wall can be considered comprised of two compartments: an anterior and a posterior compartment. The anterior compartment includes the anterior rectus sheath and the rectus muscle. The posterior compartment comprises the posterior rectus sheath, the transversalis fascia, and the peritoneum. When a large defect in the anterior compartment has to be corrected, for example, a rectus diastasis or large incisional hernia, an action on the anterior compartment is necessary; therefore, an anterior component separation has to be considered. If a loss of substance is present in the posterior compartment, a trasversus abdominis release should be accomplished. We propose an original anterior compartment mobilisation, by a posterior approach. Dissection of the posterior rectus sheet proceeds until the linea semilunaris is reached. Incision of the anterior rectus sheath permits a mobilisation of the anterior compartment by a posterior approach. A mesh is placed in a sublay position. If the abdominal wall presents a loss of substance of the posterior compartment, a transversus abdominis release (TAR) can be performed in the same time. No hernia recurrences, no wound infection, and no mesh infection have been reported. The anterior compartment mobilization permits mobilization towards the midline of rectus muscle and restoration of anterior compartment, with low morbidity rate; it can be easily associated to a large sublay mesh placement, it allows the preservation of the neurovascular bundles and rectus muscle trophism, and it can be associated with a concomitant TAR procedure for the restoration of the PC, if necessary.

Before the advent of minimally invasive techniques for ventral hernia surgery, optimal access for an open retromuscular repair (Rives-Stoppa-Wantz technique) could only be achieved at the expense of large high morbidity incisions [1]. It should be the aim of the surgeon to employ the type of incision considered to be the most suitable for that particular hernia repair to be performed. In doing so, three essentials should be achieved: accessibility, extensibility, and security [1]. The incision must not only give ready access to the abdominal wall anatomy to be investigated but also provide sufficient room for the operation to be performed [2]. The incision should be extensible in a direction that allow for any probable enlargement of the scope of the operation, but it should interfere as little as possible with functions of the abdominal wall surgery. The surgical incision and the resultant wound represent a major part of the morbidity of the abdominal wall surgery. The incision must be tailored to the patients need but is strongly influenced by the surgeon’s preference and experience. For any open incisional hernia repair, the best is to go through the previous laparotomy incision, because this minimizes further loss of tensile strength of the abdominal wall by avoiding the creation of additional fascial defects [3]. Care must be taken to avoid “tramline” or “acute angle” incisions, which could lead to devascularization of tissues. Cosmetic end results of any incision in the body are most important from patient’s point of view. Consideration should be given wherever possible, to siting the incisions in natural skin creases or along Langer’s lines. Good cosmesis helps patient morale. Much of the decision about the direction and the length of the incision depends on the type of hernia defect and the previous scar position but also on the shape of the abdominal wall. Traditionally, for an open retromuscular ventral hernia repair, a generous midline laparotomy is required, but there are some cases in which it is possible to adopt our MILA (minimally invasive laparotomy approach) technique with the same excellent results. Elliptical incisions can be used to incorporate previous scars, skin ulcerations, and/or defects. For most, and especially morbidity obese, patients with large midline hernias, an excision of the umbilicus to minimize postoperative wound morbidity is possible.

Pubic inguinal pain syndrome commonly presents as a painful groin in those sports that involve kicking and twisting movements while running such as football, rugby, and soccer. The pain experience is recognized at the common point of origin of the rectus abdominis muscle and the adductor longus tendon on the pubic bone. Although it is usually known as “sportsman’s hernia,” it may also appear in normally physically active people. Moreover it is accepted that this chronic pain caused by abdominal wall weakness occurs without a palpable hernia. For all this reason, we proposed the new name “pubic inguinal pain syndrome (PIPS).”

In 1974, Lichtenstein adopted a new “tension-free” approach using a polypropylene prosthesis to improve results [1, 2].

Giant inguinoscrotal hernias have been defined as those that extend below the midpoint of the inner thigh with the patient in the standing position [1]. Giant inguinoscrotal hernias, with a significant secondary abdominal cavity, are infrequent in developed countries; nevertheless, on rare occasions, patients visit their clinician after years of neglect and refusing to admit their problem. Even among underserved populations, the incidence of giant inguinoscrotal hernias is less than that of large inguinoscrotal hernias: indeed, this evidences the real distinction between giant and large inguinoscrotal hernias. Giant inguinoscrotal hernias are not only those that extend below the midpoint of the inner thigh when the patient is standing but also those with an anteroposterior diameter of at least 30 cm and a laterolateral diameter of about 50 cm and have been not reducible for more than 10 years (Figs. 37.1 and 37.2).

Abdominal wall hernia is very common; the prevalence in the general population is about 5% (Basile et al., Int J Surg 11, S20–S23, 2013).

Large epidemiologic and consecutive series and several retrospective and randomized controlled trials have shown the superiority of local anesthesia over general and regional anesthesias for primary inguinal hernia repair in terms of less postoperative pain, less anesthesia-related complaints, less micturition difficulties, faster discharge, and faster short-term recovery.

A Specialised Hernia Unit is a multidisciplinary programme providing state-of-the-art care for all types of hernias, from the most common to the most complex and technically challenging, from the simple primary hernia to multi-recurrent hernia or mesh-related complication (such as infection or post-operative chronic pain), from the small ventral hernia to the swiss cheese with real loss of substance incisional hernia, from the pubic inguinal pain syndrome (the so-called sportsman hernia) to the floppy abdomen postpartum.

Open anterior repair for inguinal hernia offers several distinct advantages over endoscopic repair, especially when real-world effectiveness is taken into account. The learning curve for endoscopic techniques is long, whereas the Lichtenstein and other open tension-free techniques are easier to teach and replicate at all levels. The outcomes of Lichtenstein repairs for primary inguinal hernia as performed by non-experts and supervised residents are comparable to those of experts. Moreover, open tension-free repair does not require expensive instruments or dedicated equipment, other than the prosthetic mesh. As such, it is feasible in any operating room anywhere in the world with limited costs. In our opinion, the most important advantage offered by open tension-free repair is that it can be performed under local anesthesia. Nevertheless, local anesthesia has some disadvantages: it requires training, excellent knowledge of the anatomy and the necessary technique, patience, and gentle handling of the tissues. Open inguinal hernia repair is a procedure that every surgeon should know and be able to perform because it is necessary to treat two conditions, groin hernia recurrence after a posterior approach (both laparoscopic and open) and pubic inguinal pain syndrome.

Chronic pain is a significant long-term complication that can occur after inguinal hernia repair and can compromise the patient’s quality of life. Although this complication is increasingly recognized, much controversy still exists in the literature regarding its incidence, terminology, pathogenesis and treatment strategies. In an attempt to unify the terminology, the International guidelines for prevention and management of postoperative chronic pain following inguinal hernia surgery [1], in agreement also with the IASP (International Association for the Study of Pain) definition, proposed the following definition: a pain arising as a direct consequence of a nerve lesion or a disease affecting the somatosensory system, in patients who did not have groin pain before their original hernia operation, or, if they did, the postoperative pain differs from the preoperative pain. The pain complex syndrome of postherniorrhaphy inguinodynia includes pain...

Giant inguinoscrotal hernia are a real challenge for every kind of surgeon. The technique that we adopt is suggested as a good option to deal with this cases. We report our experience in five cases of giant inguinoscrotal hernia with loss of domain from 2005 to 2012. Five patients with hernia that descended below the knees in the standing position, with an anteroposterior diameter not inferior to 30 cm and a laterolateral diameter of about 50 cm. Penis was not visible. We did the same procedure for all the five patients: single pararectus incision extended to groin region until proximal half of scrotum, isolation of the entire large sac out of the scrotal cavity, paying attention to not opening it, progressive reduction of the viscera without opening the sac with the hug technique, as shown in the video, placement of a heavyweight polypropylene meshes in the preperitoneal space, scrotal skin reductive plastic. In three of our five cases we obtained restoration of herniated viscera without resection of them. Orchiectomy was performed in all cases. No general neither wound complications were recorded. Long term follow up ranges from 8 years to 18 months: we did not record recurrence or chronic groin pain and scrotal size is normal in each patient. The technique proposed permits to treat with success giant inguinaoscrotal hernia, avoiding the use of further specific procedure such as the preoperative progressive pneumoperitoneum. All our patients were satisfied with the surgeries and their quality of daily life had definitely improved.