476 results on '"Pieri G"'
Search Results
2. RWD101 Intravitreal Therapies and Their Patterns of Use in Lombardy Region
- Author
-
Foglia, E., primary, Garagiola, E., additional, Bellavia, D., additional, Schettini, F., additional, Asperti, F., additional, Machiavelli, A., additional, Merlo, D., additional, Mainardi, G., additional, Lusuriello, P., additional, Franzin, M., additional, Soliveri, N., additional, Lombardo, R., additional, Ventura, L., additional, Pieri, G., additional, Punzi, C., additional, Fazio, M., additional, Di Carlo, C., additional, and Ferrario, L.B., additional
- Published
- 2023
- Full Text
- View/download PDF
3. Personalised management of patients with hepatocellular carcinoma: a multiparametric therapeutic hierarchy concept
- Author
-
Vitale, A, Cabibbo, G, Iavarone, M, Vigano, L, Pinato, D, Ponziani, F, Lai, Q, Casadei-Gardini, A, Celsa, C, Galati, G, Gambato, M, Crocetti, L, Renzulli, M, Giannini, E, Farinati, F, Trevisani, F, Cillo, U, Baccarani, U, Brancaccio, G, Cozzolongo, R, Cucchetti, A, De Matthaeis, N, Di Sandro, S, Famularo, S, Finotti, M, Foschi, F, Ghinolfi, D, Guarracino, M, Gruttadauria, S, Guarino, M, Kostandini, A, Lenci, I, Levi Sandri, G, Manzia, T, Marasco, G, Masarone, M, Mazzarelli, C, Melandro, F, Miele, L, Morisco, F, Nicolini, D, Pagano, D, Pelizzaro, F, Pieri, G, Piscaglia, F, Plaz Torres, M, Pravisani, R, Rendina, M, Romano, F, Russo, F, Sacco, R, Sangiovanni, A, Sposito, C, Tortora, R, Tovoli, F, Vigano, M, Violi, P, Vitale A., Cabibbo G., Iavarone M., Vigano L., Pinato D. J., Ponziani F. R., Lai Q., Casadei-Gardini A., Celsa C., Galati G., Gambato M., Crocetti L., Renzulli M., Giannini E. G., Farinati F., Trevisani F., Cillo U., Baccarani U., Brancaccio G., Cozzolongo R., Cucchetti A., De Matthaeis N., Di Sandro S., Famularo S., Finotti M., Foschi F. G., Ghinolfi D., Guarracino M., Gruttadauria S., Guarino M., Kostandini A., Lenci I., Levi Sandri G. B., Manzia T. M., Marasco G., Masarone M., Mazzarelli C., Melandro F., Miele L., Morisco F., Nicolini D., Pagano D., Pelizzaro F., Pieri G., Piscaglia F., Plaz Torres M. C., Pravisani R., Rendina M., Romano F., Russo F. P., Sacco R., Sangiovanni A., Sposito C., Tortora R., Tovoli F., Vigano M., Violi P., Vitale, A, Cabibbo, G, Iavarone, M, Vigano, L, Pinato, D, Ponziani, F, Lai, Q, Casadei-Gardini, A, Celsa, C, Galati, G, Gambato, M, Crocetti, L, Renzulli, M, Giannini, E, Farinati, F, Trevisani, F, Cillo, U, Baccarani, U, Brancaccio, G, Cozzolongo, R, Cucchetti, A, De Matthaeis, N, Di Sandro, S, Famularo, S, Finotti, M, Foschi, F, Ghinolfi, D, Guarracino, M, Gruttadauria, S, Guarino, M, Kostandini, A, Lenci, I, Levi Sandri, G, Manzia, T, Marasco, G, Masarone, M, Mazzarelli, C, Melandro, F, Miele, L, Morisco, F, Nicolini, D, Pagano, D, Pelizzaro, F, Pieri, G, Piscaglia, F, Plaz Torres, M, Pravisani, R, Rendina, M, Romano, F, Russo, F, Sacco, R, Sangiovanni, A, Sposito, C, Tortora, R, Tovoli, F, Vigano, M, Violi, P, Vitale A., Cabibbo G., Iavarone M., Vigano L., Pinato D. J., Ponziani F. R., Lai Q., Casadei-Gardini A., Celsa C., Galati G., Gambato M., Crocetti L., Renzulli M., Giannini E. G., Farinati F., Trevisani F., Cillo U., Baccarani U., Brancaccio G., Cozzolongo R., Cucchetti A., De Matthaeis N., Di Sandro S., Famularo S., Finotti M., Foschi F. G., Ghinolfi D., Guarracino M., Gruttadauria S., Guarino M., Kostandini A., Lenci I., Levi Sandri G. B., Manzia T. M., Marasco G., Masarone M., Mazzarelli C., Melandro F., Miele L., Morisco F., Nicolini D., Pagano D., Pelizzaro F., Pieri G., Piscaglia F., Plaz Torres M. C., Pravisani R., Rendina M., Romano F., Russo F. P., Sacco R., Sangiovanni A., Sposito C., Tortora R., Tovoli F., Vigano M., and Violi P.
- Abstract
Advances in the surgical and systemic therapeutic landscape of hepatocellular carcinoma have increased the complexity of patient management. A dynamic adaptation of the available staging-based algorithms is required to allow flexible therapeutic allocation. In particular, real-world hepatocellular carcinoma management increasingly relies on factors independent of oncological staging, including patients’ frailty, comorbid burden, critical tumour location, multiple liver functional parameters, and specific technical contraindications impacting the delivery of treatment and resource availability. In this Policy Review we critically appraise how treatment allocation strictly based on pretreatment staging features has shifted towards a more personalised treatment approach, in which expert tumour boards assume a central role. We propose an evidence-based framework for hepatocellular carcinoma treatment based on the novel concept of multiparametric therapeutic hierarchy, in which different therapeutic options are ordered according to their survival benefit (ie, from surgery to systemic therapy). Moreover, we introduce the concept of converse therapeutic hierarchy, in which therapies are ordered according to their conversion abilities or adjuvant abilities (ie, from systemic therapy to surgery).
- Published
- 2023
4. Hepatitis D virus-associated hepatocellular carcinoma, characteristics and outcome: An Italian Liver Cancer (ITA.LI.CA) study
- Author
-
Pasta, A., primary, Pieri, G., additional, Torres, M.C. Plaz, additional, and Giannini, E.G., additional
- Published
- 2023
- Full Text
- View/download PDF
5. Systematic review and meta-analysis of safety and efficacy of atezolizumab/ bevacizumab in Child-Pugh class B patients with hepatocellular carcinoma
- Author
-
Pasta, A., primary, Calabrese, F., additional, Jaffe, A., additional, Labanca, S., additional, Marenco, S., additional, Pieri, G., additional, Torres, M.C. Plaz, additional, Strazzabosco, M., additional, and Giannini, E.G., additional
- Published
- 2023
- Full Text
- View/download PDF
6. Search for neutrino oscillations on a long base-line at the CHOOZ nuclear power station
- Author
-
Apollonio, M., Baldini, A., Bemporad, C., Caffau, E., Cei, F., Declais, Y., de Kerret, H., Dieterle, B., Etenko, A., Foresti, L., George, J., Giannini, G., Grassi, M., Kozlov, Y., Kropp, W., Kryn, D., Laiman, M., Lane, C. E., Lefievre, B., Machulin, I., Martemyanov, A., Martemyanov, V., Mikaelyan, L., Nicolo, D., Obolensky, M., Pazzi, R., Pieri, G., Price, L., Riley, S., Reeder, R., Sabelnikov, A., Santin, G., Skorokhvatov, M., Sobel, H., Steele, J., Steinberg, R., Sukhotin, S., Tomshaw, S., Veron, D., and Vyrodov, V.
- Subjects
High Energy Physics - Experiment - Abstract
This final article about the CHOOZ experiment presents a complete description of the electron antineutrino source and detector, the calibration methods and stability checks, the event reconstruction procedures and the Monte Carlo simulation. The data analysis, systematic effects and the methods used to reach our conclusions are fully discussed. Some new remarks are presented on the deduction of the confidence limits and on the correct treatment of systematic errors., Comment: 41 pages, 59 figures, Latex file, accepted for publication by Eur.Phys.J.C
- Published
- 2003
- Full Text
- View/download PDF
7. Limits on Neutrino Oscillations from the CHOOZ Experiment
- Author
-
Apollonio, M., Baldini, A., Bemporad, C., Caffau, E., Cei, F., Declais, Y., de Kerret, H., Dieterle, B., Etenko, A., Foresti, L., George, J., Giannini, G., Grassi, M., Kozlov, Y., Kropp, W., Kryn, D., Laiman, M., Lane, C. E., Lefievre, B., Machulin, I., Martemyanov, A., Martemyanov, V., Mikaelyan, L., Nicolo, D., Obolensky, M., Pazzi, R., Pieri, G., Price, L., Riley, S., Reeder, R., Sabelnikov, A., Santin, G., Skorokhvatov, M., Sobel, H., Steele, J., Steinberg, R., Sukhotin, S., Tomshaw, S., Veron, D., and Vyrodov, V.
- Subjects
High Energy Physics - Experiment - Abstract
We present new results based on the entire CHOOZ data sample. We find (at 90% confidence level) no evidence for neutrino oscillations in the anti_nue disappearance mode, for the parameter region given by approximately Delta m**2 > 7 x 10**-4 eV^2 for maximum mixing, and sin**2(2 theta) = 0.10 for large Delta m**2. Lower sensitivity results, based only on the comparison of the positron spectra from the two different-distance nuclear reactors, are also presented; these are independent of the absolute normalization of the anti_nue flux, the cross section, the number of target protons and the detector efficiencies., Comment: 19 pages, 11 figures, Latex file
- Published
- 1999
- Full Text
- View/download PDF
8. Determination of neutrino incoming direction in the CHOOZ experiment and Supernova explosion location by scintillator detectors
- Author
-
Apollonio, M., Baldini, A., Bemporad, C., Caffau, E., Cei, F., Declais, Y., de Kerret, H., Dieterle, B., Etenko, A., Foresti, L., George, J., Giannini, G., Grassi, M., Kozlov, Y., Kropp, W., Kryn, D., Laiman, M., Lane, C. E., Lefievre, B., Machulin, I., Martemyanov, A., Martemyanov, V., Mikaelyan, L., Nicolo, D., Obolensky, M., Pazzi, R., Pieri, G., Price, L., Riley, S., Reeder, R., Sabelnikov, A., Santin, G., Skorokhvatov, M., Sobel, H., Steele, J., Steinberg, R., Sukhotin, S., Tomshaw, S., Veron, D., and Vyrodov, V.
- Subjects
High Energy Physics - Experiment ,Nuclear Experiment - Abstract
The CHOOZ experiment measured the antineutrino flux at a distance of about 1 Km from two nuclear reactors in order to detect possible neutrino oscillations with squared mass differences as low as 10**-3 eV**2 for full mixing. We show that the data analysis of the electron antineutrino events, collected by our liquid scintillation detector, locates the antineutrino source within a cone of half-aperture of about 18 degrees at the 68% C.L.. We discuss the implications of this experimental result for tracking down a supernova explosion., Comment: Submitted to Physical Review D
- Published
- 1999
- Full Text
- View/download PDF
9. OC.16.1 EFFECT OF HIATAL HERNIA AND ESOPHAGOGASTRIC JUNCTION MORPHOLOGY ON OESOPHAGEAL MOTILITY: NEW EVIDENCES FROM HIGH RESOLUTION MANOMETRY
- Author
-
Kayali, S., primary, Calabrese, F., additional, Facchini, C., additional, Marabotto, E., additional, Furnari, M., additional, Bodini, G., additional, Pieri, G., additional, Giannini, E.G., additional, and Zentilin, P., additional
- Published
- 2023
- Full Text
- View/download PDF
10. OC.12.4 PROGNOSTIC FACTORS IN PATIENTS WITH HEPATOCELLULAR CARCINOMA (HCC) TREATED WITH LENVATINIB
- Author
-
Sacco, R., primary, Ciruolo, M., additional, Paolillo, R., additional, Ramai, D., additional, Tortora, R., additional, Di, Costanzo G.G., additional, Burlone, M., additional, Pirisi, M., additional, Federico, P., additional, Daniele, B., additional, Silletta, M., additional, Gallo, P., additional, Cocuzza, C., additional, Russello, M., additional, Cabibbo, G., additional, Cesario, S., additional, Masi, G., additional, Marzi, L., additional, Mega, A., additional, Granito, A., additional, Pieri, G., additional, Giannini, E., additional, Gadaleta-Caldarola, G., additional, Dadduzio, V., additional, Giordano, G., additional, Giacomelli, L., additional, Papa, S., additional, Renzulli, M., additional, Maida, M., additional, Ghidini, M., additional, and Facciorusso, A., additional
- Published
- 2023
- Full Text
- View/download PDF
11. HSD15 Biosimilars and Originators: Utilization and Costs in Lombardy Region
- Author
-
Foglia, E, primary, Bellavia, D, additional, Asperti, F, additional, D'Angelo, C, additional, Esposito, A, additional, Langella, R, additional, Cervi, L, additional, Caravella, G, additional, Mainardi, E, additional, Ferrari, E, additional, Pieri, G, additional, and Ferrario, LB, additional
- Published
- 2022
- Full Text
- View/download PDF
12. Analysis of sea surface temperature maps via topological machine learning
- Author
-
Conti F., Papini O., Moroni D., Pieri G., Reggiannini M., and Pascali M. A.
- Subjects
Sea surface temperature map ,Remote sensing ,TDA ,Marine mesoscale patterns - Abstract
Computational methods to leverage topological features occurring in signals and images are currently one of the most innovative trends in applied mathematics. In this paper a pipeline of topological machine learning is applied to the challenging task of classifying four specific marine mesoscale patterns from remote sensing data, i.e., Sea Surface Temperature maps of the southwestern region of the Iberian Peninsula. Our preliminary study achieves an accuracy of 56% in the 4-label classification. Such results are encouraging, especially considering that the data are affected by noise and that there are low-quality/missing data. Also, the paper devises directions for future improvements.
- Published
- 2023
13. Italy and Croatia : Pomo Pits, Central Adriatic Sea (GSA 17) Adriatic UWTV Surveys and Pomo monitoring activity
- Author
-
Martinelli M., Medve?ek D., Domenichetti F., Canduci G., Giuliani G., Zacchetti L., Pieri G., Belardinelli A., Chiarini M., Guicciardi S., Grilli F., Penna P., Scarpini P., Cvitani? R., Isajlovic I., and Vrgoc N.
- Subjects
Nephrops norvegicus ,Adriatic Sea ,UWTV - Abstract
The Pomo (or Jabuka) Pits area is one of the main fishing ground for Norway Lobster Nephrops norvegicus and European hake Merluccius merluccius within the GFCM Geographical Sub Areas 17 (Northern and Central Adriatic Sea) and it is shared by the Italian and the Croatian fleets. Furthermore, this represents a well-known nursery area for M. merluccius and hosts a distinct population of N. norvegicus, characterized by small-sized mature individuals. Due to a decline in landing of both species for the Adriatic Sea, since 2015 the Italian and the Croatian governments implemented some protection measures in that area. Eventually in 2018, the GFCM established a Fishery Restricted Area. Since 2009 the area is yearly monitored by CNR IRBIM in collaboration with IOF Split. From 2009 to 2019 (except 2011 and 2018), a spring UWTV survey was conducted in the Pomo Pits area jointly by CNR-IRBIM Ancona and IOF Split, on board the CNR R/V Dallaporta; the Pomo Pits UWTV time series has been recently included, as a tuning index, in new modeling approaches tested for the Adriatic N. norvegicus stock assessment. Trials on automatic burrow tracking and counting have also been recently conducted on the Adriatic UWTV footage in the framework of the EU H2020 NAUTILOS project.
- Published
- 2023
14. Working Group on Nephrops Surveys (WGNEPS; outputs from 2022 meeting)
- Author
-
Aguzzi J., Aristegui-Ezquibela M., Burgos C., Chatzievangelou D., Doyle J., Fallon N., Fifas S., González-Herraiz I., Jonsson P., Lundy M., Martinelli M., Medve?ek D., Naseer A., Nava E., Nawri N., Jónasson J. P., Pereira B., Pieri G., Silva C., Tibone M., Valeiras J., Vila Y., Weetman A., and Wieland K.
- Subjects
Fisheries and aquaculture ,Technologies and data ,Adriatic Sea (ICES adjacent region) ,UWTV ,Nephrops ,Ecosystem observation, processes and dynamics ,Survey ,All ICES Ecoregions - Abstract
The Working Group on Nephrops Surveys (WGNEPS) is the international coordination group for Nephrops underwater television and trawl surveys within ICES. This report summarizes the national contributions on the results of the surveys conducted in 2022 together with time series covering all survey years, problems encountered, data quality checks and technological improvements as well as the planning for survey activities for 2023. In total, 21 surveys covering 26 functional units (FU’s) in the ICES area and 1 geographical subarea (GSA) in the Adriatic Sea were discussed and further improvements in respect to survey design and data analysis standardization and the use of most recent technology were reviewed. The first exploratory UWTV survey on the FU 25 Nephrops grounds was also presented to the group. The results of the evaluation of reference sets for FU3&4 Skagerrak/Kattegat were accepted following the process set down by the 2018 workshop (WKNEPS). An alternative method estimate Nephrops abundance was shown to the group using the recently published R package sdmTMB. The group agreed to hold a workshop in 2025 to address burrow size estimations to update correction factors and terms of reference for this to be agreed at next meeting. Automatic burrow detection based on deep learning methods continues to show promising results where datasets from multiple institutes were used. Plans are being progressed for an international Nephrops UWTV database to be established at the ICES data centre with a sub-group.
- Published
- 2023
- Full Text
- View/download PDF
15. Special Issue 'Research Progress on Ocean Observations Technology and Information Systems'
- Author
-
Tsabaris C. and Pieri G.
- Subjects
Fixed platforms ,Sensors' integration ,Ocean networks ,Ocean observation systems ,Marine information systems ,Maritime data processing and modeling ,Environmental monitoring ,Mobile platforms - Abstract
The oceans play a crucial role in the global ecosystem for shaping climate and weather trends, water management and health, and the biogeochemical cycles, representing valuable sources of oil, food, minerals and renewable energy. Although increasingly mature marine observation technologies have been developed during recent decades for a better understanding of the oceans, the new advances of existing operational observing systems have been constrained by limited cooperation and interaction between the managers of existing ocean networks on earth as well as between the observing units. Furthermore, the development of smart in situ marine sensors to be integrated into existing fixed units (such as landers and mooring buoys) as well as in mobile units (such as AUVs, ROVs, ships of opportunity, marine drones, Argo floats and gliders) are under development in the frame of various European and international projects. In recent years, a lot of progress has been made for the Ocean Observation Technologies and Information Systems by developing cost effective and miniaturized sensing devices with very low power consumption that would be directly integrated as a "plug and play" operational mode in existing sensor networks. Additionally, a lot of effort has been made to develop acoustic communication methods and modules to transmit the data from the deep ocean as well as cellular systems for transmitting the data of the marine sensors in near real-time mode using 4G/5G protocols (especially in coastal areas). In order to improve the processes that take place globally in the oceans (such as weather monitoring and forecasting, climate variability, sea level rise, natural hazards, ocean acidification, health of the ocean, pollution and ecosystem functioning, energy, economic development and coastal management, public safety, security, training and education), new research is ongoing to improve and optimize infrastructures and updated models at the international level. The state-of-the-art in situ marine sensors with the capability to be easily integrated into ocean platforms combined with innovative communication and information systems for real-time data transmission will emerge as new features of both forecasting methods and smart emergency systems to protect humans.
- Published
- 2023
16. Thesaurus Project: Design of New Autonomous Underwater Vehicles for Documentation and Protection of Underwater Archaeological Sites
- Author
-
Allotta, B., Bargagliotti, S., Botarelli, L., Caiti, A., Calabrò, V., Casa, G., Cocco, M., Colantonio, S., Colombo, C., Costa, S., Fanfani, M., Franchi, L., Gambogi, P., Gualdesi, L., La Monica, D., Magrini, M., Martinelli, M., Moroni, D., Munafò, A., Pace, G., Papa, C., Pascali, M. A., Pieri, G., Reggiannini, M., Righi, M., Salvetti, O., Tampucci, M., Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Ioannides, Marinos, editor, Fritsch, Dieter, editor, Leissner, Johanna, editor, Davies, Rob, editor, Remondino, Fabio, editor, and Caffo, Rossella, editor
- Published
- 2012
- Full Text
- View/download PDF
17. Characteristics and Outcomes of Hepatocellular Carcinoma (HCC) in Patients with Autoimmune Hepatitis (AIH): Insights from the Italian Liver Cancer (ITA.LI.CA) Database.
- Author
-
Pasta, A., Pieri, G., Torres, M.C. Plaz, Trevisani, F., and Giannini, E.G.
- Abstract
The incidence of HCC in patients with autoimmune hepatitis AIH patients is low (0.09% per year), with higher risk in those with additional risk factors. To report characteristics and outcomes of patients with AIH and HCC. We analyzed data from the ITA.LI.CA database (2009-2022) including 8,038 HCC and identified 18 patients (0.2%) with AIH and HCC. We evaluated liver disease-related characteristics, modality of HCC diagnosis, tumor stage, treatment, recurrence, overall survival (OS), and causes of death. Median age was 67.2 years, and male patients represented 50.0% of cases. Most patients had cirrhosis (90%). Two patients (11.1%) had Primary Biliary Cholangitis overlap, three (16.7%) concomitant alcohol abuse, while 4 (22.2%) and 3 (16.7%) were overweight and obese, respectively. Median MELD score was 11 (IQR 9-13). HCC diagnosis occurred primary during surveillance (55.6%). Most patients had single tumour (77.8%), median HCC diameter was 2.8cm (1.5–3.2), three patients (16.7%) had extra-hepatic spread or macro-vascular invasion, and 72.2% were Milan-in. Treatment with curative intent was performed in 11 patients (33.3% ablation, 22.2% resection, 5.5% transplantation). Trans-arterial chemoembolization was carried out in 6 patients (33.3%), and one patient (5.5%) was managed with best supportive care. Objective response was observed in 66.7% of patients, and early recurrence occurred in 2 patients (11.8%). Median OS was 41.7 months, and main causes of death were end-stage liver disease (57.1%) and HCC progression (42.9%). OS was longer in patients under surveillance than in those diagnosed incidentally or due to symptoms (27.3 vs. 62.8 months, p=0.049). HCC in AIH is a rare event, occurring prevalently in older, male patients with cirrhosis, and with frequent concurrent factors for HCC occurrence. A high surveillance rate is associated with favorable staging at diagnosis, and with access to potentially curative treatments, thus resulting in improved survival. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
18. Pattern of macrovascular invasion in hepatocellular carcinoma
- Author
-
Guarino, M., Cucchetti, A., Pontillo, G., Farinati, F., Benevento, F., Rapaccini, G. L., Di Marco, M., Caturelli, E., Zoli, M., Rodolfo, S., Cabibbo, G., Marra, F., Mega, A., Gasbarrini, A., Svegliati-Baroni, G., Foschi, F. G., Missale, G., Masotto, A., Nardone, G., Raimondo, G., Azzaroli, F., Vidili, G., Oliveri, F., Trevisani, F., Giannini, E. G., Morisco, F., Biselli, M., Caraceni, P., Garuti, F., Gramenzi, A., Neri, A., Rampoldi, D., Santi, V., Forgione, A., Granito, A., Muratori, L., Piscaglia, F., Sansone, V., Tovoli, F., Dajti, E., Marasco, G., Ravaioli, F., Cappelli, A., Golfieri, R., Mosconi, C., Renzulli, M., Cela, E. M., Facciorusso, A., Pelizzaro, F., Imondi, A., Sartori, A., Penzo, B., Cacciato, V., Casagrande, E., Moscatelli, A., Pellegatta, G., Pieri, G., de Matthaeis, N., Allegrini, G., Lauria, V., Ghittoni, G., Pelecca, G., Chegai, F., Coratella, F., Ortenzi, M., Olivari, A., Inno, A., Marchetti, F., Busacca, A., Camma, C., Di Martino, V., Rizzo, G. E. M., Franze, M. S., Saitta, C., Sauchella, A., Bevilacqua, V., Borghi, A., Gardini, A. C., Conti, F., Berardinelli, D., Ercolani, G., Napoli, L., Campani, C., Di Bonaventura, C., Gitto, S., Coccoli, P., Malerba, A., Capasso, M., Fiorentino, A., Pignata, L., Cossiga, V., Romagnoli, V., Guarino M., Cucchetti A., Pontillo G., Farinati F., Benevento F., Rapaccini G.L., Di Marco M., Caturelli E., Zoli M., Rodolfo S., Cabibbo G., Marra F., Mega A., Gasbarrini A., Svegliati-Baroni G., Foschi F.G., Missale G., Masotto A., Nardone G., Raimondo G., Azzaroli F., Vidili G., Oliveri F., Trevisani F., Giannini E.G., Morisco F., Biselli M., Caraceni P., Garuti F., Gramenzi A., Neri A., Rampoldi D., Santi V., Forgione A., Granito A., Muratori L., Piscaglia F., Sansone V., Tovoli F., Dajti E., Marasco G., Ravaioli F., Cappelli A., Golfieri R., Mosconi C., Renzulli M., Cela E.M., Facciorusso A., Pelizzaro F., Imondi A., Sartori A., Penzo B., Cacciato V., Casagrande E., Moscatelli A., Pellegatta G., Pieri G., de Matthaeis N., Allegrini G., Lauria V., Ghittoni G., Pelecca G., Chegai F., Coratella F., Ortenzi M., Olivari A., Inno A., Marchetti F., Busacca A., Camma C., Di Martino V., Rizzo G.E.M., Franze M.S., Saitta C., Sauchella A., Bevilacqua V., Borghi A., Gardini A.C., Conti F., Berardinelli D., Ercolani G., Napoli L., Campani C., Di Bonaventura C., Gitto S., Coccoli P., Malerba A., Capasso M., Fiorentino A., Pignata L., Cossiga V., Romagnoli V., Guarino, M., Cucchetti, A., Pontillo, G., Farinati, F., Benevento, F., Rapaccini, G. L., Di Marco, M., Caturelli, E., Zoli, M., Rodolfo, S., Cabibbo, G., Marra, F., Mega, A., Gasbarrini, A., Svegliati-Baroni, G., Foschi, F. G., Missale, G., Masotto, A., Nardone, G., Raimondo, G., Azzaroli, F., Vidili, G., Oliveri, F., Trevisani, F., Giannini, E. G., Morisco, F., Biselli, M., Caraceni, P., Garuti, F., Gramenzi, A., Neri, A., Rampoldi, D., Santi, V., Forgione, A., Granito, A., Muratori, L., Piscaglia, F., Sansone, V., Tovoli, F., Dajti, E., Marasco, G., Ravaioli, F., Cappelli, A., Golfieri, R., Mosconi, C., Renzulli, M., Cela, E. M., Facciorusso, A., Pelizzaro, F., Imondi, A., Sartori, A., Penzo, B., Cacciato, V., Casagrande, E., Moscatelli, A., Pellegatta, G., Pieri, G., de Matthaeis, N., Allegrini, G., Lauria, V., Ghittoni, G., Pelecca, G., Chegai, F., Coratella, F., Ortenzi, M., Olivari, A., Inno, A., Marchetti, F., Busacca, A., Camma, C., Di Martino, V., Rizzo, G. E. M., Franze, M. S., Saitta, C., Sauchella, A., Bevilacqua, V., Borghi, A., Gardini, A. C., Conti, F., Berardinelli, D., Ercolani, G., Napoli, L., Campani, C., Di Bonaventura, C., Gitto, S., Coccoli, P., Malerba, A., Capasso, M., Fiorentino, A., Pignata, L., Cossiga, V., and Romagnoli, V.
- Subjects
Ablation Techniques ,Male ,Registrie ,Cirrhosis ,Clinical Biochemistry ,Mesenteric Vein ,loco-regional treatment ,030204 cardiovascular system & hematology ,Biochemistry ,Gastroenterology ,surgery ,Antineoplastic Agent ,Liver disease ,0302 clinical medicine ,Non-alcoholic Fatty Liver Disease ,cirrhosis ,hepatocellular carcinoma ,portal vein thrombosis ,transplantation ,Ascites ,Ablation Technique ,Registries ,030212 general & internal medicine ,Chronic ,Settore MED/12 - Gastroenterologia ,Portal Vein ,Liver Diseases ,Liver Neoplasms ,General Medicine ,Middle Aged ,Sorafenib ,Prognosis ,Hepatitis B ,Alcoholic ,Hepatitis C ,Tumor Burden ,Survival Rate ,Italy ,Liver Neoplasm ,Hepatocellular carcinoma ,Ascite ,Female ,medicine.symptom ,Liver cancer ,Human ,medicine.medical_specialty ,Carcinoma, Hepatocellular ,Prognosi ,Antineoplastic Agents ,End Stage Liver Disease ,03 medical and health sciences ,Mesenteric Veins ,Hepatitis B, Chronic ,Internal medicine ,medicine ,Humans ,Hepatectomy ,Neoplasm Invasiveness ,portal vein thrombosi ,Liver Diseases, Alcoholic ,Aged ,Neoplasm Invasivene ,Performance status ,business.industry ,Carcinoma ,Settore MED/09 - MEDICINA INTERNA ,Patient Acuity ,Hepatocellular ,Hepatitis C, Chronic ,medicine.disease ,Liver Transplantation ,Transplantation ,Liver function ,business ,cirrhosi - Abstract
Background and aims: In patients with hepatocellular carcinoma (HCC), macrovascular invasion (MaVI) limits treatment options and decreases survival. Detailed data on the relationship between MaVI extension and patients' characteristics, and its impact on patients' outcome are limited. We evaluated the prevalence and extension of MaVI in a large cohort of consecutive HCC patients, analysing its association with liver disease and tumour characteristics, as well as with treatments performed and patients' survival. Methods: We analysed data of 4774 patients diagnosed with HCC recorded in the Italian Liver Cancer (ITA.LI.CA) database (2008-2018). Recursive partition analysis (RPA) was performed to evaluate interactions between MaVI, clinical variables and treatment, exploring the inter-relationship determining overall survival. Results: MaVI prevalence was 11.1%, and median survival of these patients was 6.0months (95% CI, 5.1-7.1). MaVI was associated with younger age at diagnosis, presence of symptoms, worse Performance Status (PS) and liver function, high alphafetoprotein levels and large HCCs. MaVI extension was associated with worse PS, ascites and greater impairment in liver function. RPA identified patients' categories with different treatment indications and survival, ranging from 2.4months in those with PS>1 and ascites, regardless of MaVI extension (receiving best supportive care in 90.3% of cases), to 14.1months in patients with PS 0-1, no ascites and Vp1-Vp2 MaVI (treated with surgery in 19.1% of cases). Conclusions: MaVI presence and extension, together with PS and ascites, significantly affect patients' survival and treatment selection. The decision tree based on these parameters may help assess patients' prognosis and inform therapeutic decisions.
- Published
- 2021
19. Induction TPF followed by concomitant treatment versus concomitant treatment alone in locally advanced head and neck cancer. A phase II–III trial
- Author
-
Ghi, M. G., Paccagnella, A., Ferrari, D., Foa, P., Alterio, D., Codecà, C., Nolè, F., Verri, E., Orecchia, R., Morelli, F., Parisi, S., Mastromauro, C., Mione, C. A., Rossetto, C., Polsinelli, M., Koussis, H., Loreggian, L., Bonetti, A., Campostrini, F., Azzarello, G., D’Ambrosio, C., Bertoni, F., Casanova, C., Emiliani, E., Guaraldi, M., Bunkheila, F., Bidoli, P., Niespolo, R. M., Gava, A., Massa, E., Frattegiani, A., Valduga, F., Pieri, G., Cipani, T., Da Corte, D., Chiappa, F., and Rulli, E.
- Published
- 2017
- Full Text
- View/download PDF
20. T.08.3 CHARACTERISTICS AND SURVIVAL OF PATIENTS WITH PRIMARY BILIARY CHOLANGITIS AND HEPATOCELLULAR CARCINOMA
- Author
-
Giannini, E.G., primary, Pieri, G., additional, Labanca, S., additional, Plaz Torres, M.C., additional, Gasbarrini, A., additional, Biasini, E., additional, Campani, C., additional, Cazzagon, N., additional, Foschi, F.G., additional, Mega, A., additional, Masotto, A., additional, Raimondo, G., additional, Rapaccini, G.L., additional, Sacco, R., additional, Caturelli, E., additional, Guarino, M., additional, Tovoli, F., additional, Vidili, G., additional, Brunetto, M.R., additional, Nardone, G., additional, Svegliati-Baroni, G., additional, Magalotti, D., additional, Azzaroli, F., additional, Cabibbo, G., additional, Di Marco, M., additional, Sangiovanni, A., additional, and Trevisani, F., additional
- Published
- 2022
- Full Text
- View/download PDF
21. Studio e analisi delle architetture di reti convolutive
- Author
-
Moroni D., Papini O., Pascali M. A., Pieri G., and Reggiannini M.
- Subjects
Architetture ,Reti convolutive - Abstract
Questo rapporto tecnico di progetto è il risultato del contributo fornito dal Laboratorio Segnali e Immagini dell'ISTI-CNR per il documento di progetto RTOD-SYS-SDD-010-INT per il progetto RTOD (Real-Time Object Detection mediante Machine Learning basato su tecnologia Low-Power GPU). In particolare, il rapporto studia e discute delle varie possibilità di architetture di reti convolutive che sono state valutate e che potranno essere utilizzate nel contesto del progetto per effettuare delle categorizzazioni di immagini mediante algoritmi di machine learning.
- Published
- 2022
22. NAUTILOS - GEN - Requirement No. 10
- Author
-
Pieri G., Zugic N., Ntoumas M., Martinelli M., and Chatzinikolaou E.
- Subjects
Ethics ,Environmental observation ,Citizen Science ,Demonstration - Abstract
D13.7 deliverable is relative to Ethics Requirement No. 10 as a General requirement to submit a report by the Ethics Board as a deliverable at the end of each reporting period. This document represents the first report of such type. Describing the activities and updates of the NAUTILOS Ethics Advisory Board for this first period of the project from M1 till M18.
- Published
- 2022
23. NAUTILOS - Data Management Plan - 1st periodic report update
- Author
-
Novellino A. and Pieri G.
- Subjects
Data management plan - Abstract
In this deliverable, an update of the DMP at M18 will be reported.
- Published
- 2022
24. NAUTILOS - Fully developed graphic user interface. Accompanying report
- Author
-
Tampucci M., Pieri G., and Volpini F.
- Subjects
Graphical user interface ,data visualisation ,Data management - Abstract
This deliverable consist of the deployment of the project's web portal through which the storage and management of the integrated data regarding NAUTILOS, and the services defined and implemented during Task 8.4 have been organised. The implemented tools and services for data management and visualisation, designed in close connection with end-users requirements, are described.
- Published
- 2022
25. NAUTILOS - External advisory board report 2
- Author
-
Pieri G.
- Subjects
External Advisory Board - Abstract
An annual report and evaluation provided by the External Advisory Board provides their overall assessment of NAUTILOS and advice on the project's future direction. The following deliverable is the report following the EAB at the end of the project's second year in M24.
- Published
- 2022
26. Automated image processing for remote sensing data classification
- Author
-
Reggiannini M., Papini O., and Pieri G.
- Subjects
Remote Sensing ,Machine Learning ,Image Processing ,Climate Change ,Sea Surface Temperature ,Mesoscale Patterns - Abstract
Remote sensing technologies allow for continuous and valuable monitoring of the Earth's various environments. In particular, coastal and ocean monitoring presents an intrinsic complexity that makes such monitoring the main source of information available. Oceans, being the largest but least observed habitat, have many different factors affecting theirs faunal variations. Enhancing the capabilities to monitor and understand the changes occurring allows us to perform predictions and adopt proper decisions. This paper proposes an automated classification tool to recognise specific marine mesoscale events. Typically, human experts monitor and analyse these events visually through remote sensing imagery, specifically addressing Sea Surface Temperature data. The extended availability of this kind of remote sensing data transforms this activity into a time-consuming and subjective interpretation of the information. For this reason, there is an increased need for automated or at least semi-automated tools to perform this task. The results presented in this work have been obtained by applying the proposed approach to images captured over the southwestern region of the Iberian Peninsula.
- Published
- 2022
27. Special Issue 'Intelligent Systems Applied to Maritime Environment Monitoring'
- Author
-
Pieri G.
- Subjects
Ocean data management and processing ,Marine information systems ,Operational oceanography ,Smart integration of systems and platforms for maritime observations ,Marine data modelling ,Methods for maritime environment monitoring ,Intelligent technologies for marine environmental applications ,Demonstration of improved marine observing systems ,Smart technologies applied in operational maritime environment - Abstract
With the intention of extending knowledge about the ocean and the maritime environment, this Special Issue focuses on all the many intelligent systems and applications that, through technologies integrated on observational platforms, can provide tools and services for increasing the availability of data regarding all ocean environmental variables. Among the already existing platforms and technologies for ocean observation, this Special Issue aims to expand the possible application of intelligent systems and tools that operate in this context. Contributions can vary from tools for automatic collection and dispatching of information to systems for management and processing of environmental data through to methods applied to new or well-established technologies for performing consistent and standardised intelligent processing of collected data. The intended coverage for this Special Issue concerns systems, applications, and models that aim to improve the current observation tools and services and expand the availability of data in terms of higher spatial resolution, temporal regularity, and length than what is currently available at the European scale. The Special Issue also aims to democratise monitoring of the marine environment for traditional and non-traditional data users such as citizen scientists. All articles from academia, the industry, or environmental stakeholders are welcome.
- Published
- 2022
28. SI-Lab annual research report 2021
- Author
-
Righi M., Leone G. R., Carboni A., Caudai C., Colantonio S., Kuruoglu E. E., Leporini B., Magrini M., Paradisi P., Pascali M. A., Pieri G., Reggiannini M., Salerno E., Scozzari A., Tonazzini A., Fusco G., Galesi G., Martinelli M., Pardini F., Tampucci M., Berti A., Bruno A., Buongiorno R., Carloni G., Conti F., Germanese D., Ignesti G., Matarese F., Omrani A., Pachetti E., Papini O., Benassi A., Bertini G., Coltelli P., Tarabella L., Straface S., Salvetti O., and Moroni D.
- Subjects
Human-Computer Interaction ,Artificial Intelligence ,Signal Processing ,Intelligent systems ,Topological data analysis ,Quality-of-Life ,Computer vision ,Inclusion and accessibility - Abstract
The Signal & Images Laboratory is an interdisciplinary research group in computer vision, signal analysis, intelligent vision systems and multimedia data understanding. It is part of the Institute of Information Science and Technologies (ISTI) of the National Research Council of Italy (CNR). This report accounts for the research activities of the Signal and Images Laboratory of the Institute of Information Science and Technologies during the year 2021.
- Published
- 2022
29. New technology and data collection for improving our understanding of the marine environment
- Author
-
Pieri G., Bebianno M., Chatzinikolaou E., Cocco M., Dimitrova L., Fahning J., Geraskova V., João A., King A., Lusher A., Malardé D., Martinelli M., Martins F., Mazza M., Novellino A., Ntoumas M., Sá S., Smerdon A., Triantafyllou G., and Torres A.
- Subjects
Ocean Data ,Environmental data management ,Environmental monitoring ,Marine observation - Abstract
Introduction and Objective The H2020 NAUTILOS project aims to fill existing gaps in marine observation and modelling through the development of innovative and cost-effective technologies and observational methodologies for use in a wide range of crucial environmental contexts and sectors that can further support EU policies. The H2020 NAUTILOS project fills marine observation and modelling gaps by developing and deploying new technologies, promoting innovative and cost-effective methods in a wide range of crucial environmental settings and EU policy-related applications. Material and Methods NAUTILOS is developing innovative and cost-effective sensors and samplers for physical, chemical, and biological essential ocean variables in addition to micro-/nano-plastics. Newly developed technologies are integrated into diverse observing platforms, i.e. ships of opportunity, research vessels, surface and autonomous underwater vehicles, landers, fixed observatories, Argo floats, and Animal-borne instrumentation modules, to be deployed in key environmental settings. Results and Data relevance NAUTILOS will contribute to improving future ocean observation and forecasting capabilities through its holistic approach, which includes new sensors, new data to feed metocean forecast models, and the assessment of the forecasting capabilities, i.e. (OSSE) NAUTILOS data products FAIRness includes adopting standard vocabularies and open data publishing systems interoperable with European and international Ocean Data integrators. Moreover, synergies with relevant initiatives, Citizen Science campaigns and capacity building courses are also planned to reach out to all relevant stakeholders and users and promote free access and exchange of scientific data and knowledge. Conclusion The project will improve our understanding of environmental fluctuations and anthropogenic impacts in the oceans, relevant to aquaculture, fisheries and marine litter. Moreover, it will also complement and contribute to expanding European observation tools and services to obtain data collection at a much higher spatial resolution, temporal regularity and length than currently available at the European scale, and further democratise the marine environment's monitoring.
- Published
- 2022
30. NAUTILOS - Citizen Science tools and interface
- Author
-
Pieri G. and Tampucci M.
- Subjects
Citizen Science ,Smartphone App ,Interface - Abstract
This deliverable will consist of the specific tools and interface for supporting the Citizen Science Campaigns, to integrate the data produced during these activities (see Task 12.2) within the web portal. The interface, realised in Task 8.4, will be based on geo-referenced maps indicating, for instance, plastic litter data. An accompanying report with the guidelines for the usage of these tools and interface will be produced.
- Published
- 2022
31. NAUTILOS - Automatic image analysis tools
- Author
-
Pieri G., Reggiannini M., and Papini O.
- Subjects
Artificial intelligence ,Automatic tools ,Marine environment ,Image analysis - Abstract
This deliverable will consist of the implementation of image analysis tools based on methods and algorithms designed explicitly to perform different automatic classifications. These tools will be used and applied both on already available and acquired images during the project. An accompanying report describing the tools will be produced.
- Published
- 2022
32. A methodological approach for combining super-resolution and pattern-recognition to image identification
- Author
-
D’Acunto, M., Pieri, G., Righi, M., and Salvetti, O.
- Published
- 2014
- Full Text
- View/download PDF
33. Thromboembolic events in prospectively enrolled series of patients with cirrhosis followed for one year.
- Author
-
Calabrese, F., Pasta, A., Labanca, S., Marenco, S., Pieri, G., Torres, M.C. Plaz, and Giannini, E.G.
- Abstract
Coagulation in cirrhosis involves a complex imbalance between procoagulant and anticoagulant factors due to liver dysfunction. This results in a delicate hemostatic equilibrium that increases the risk of both bleeding and thrombosis. To analyze the occurrence of thromboembolic events in a prospective series of patients with liver cirrhosis, and to assess patients' characteristics. We prospectively enrolled 188 patients with cirrhosis admitted to our gastrointestinal ward (December 2021-December 2022). We evaluated general and liver disease-related characteristics as well as the incidence of venous thromboembolism (VTE), and death during the first year following hospital admission. Median age was 63 years, and 72.9% were males. The primary cause of hospitalization was acute decompensation (n=101, 53.7%), followed by hepatocellular carcinoma (n=34, 18.1%) or liver-related elective diagnostic-therapeutic procedures (28, 14.9%). Twenty-five (13.3%) patients were admitted due to non-liver related events. The median length of hospitalization was 9 days (IQR 5-14). Most of patients had decompensated cirrhosis (Child-Pugh B: 41.5%; Child-Pugh C: 26.6%), with median MELD-Na=14, and clinically significant portal-hypertension (CSPH) in 148 (78.7%). Sixty-two (32.9%) patients had hepatocellular carcinoma. Thirty-one patients (16.5%) were on anticoagulants. During a 1-year follow-up, three (1.6%) patients experienced VTE while 26 (13.8%) patients had variceal bleeding. Overall mortality was 42.0% (n=79). Padua and Improve-VTE risk scores, MELD-Na, Child-Pugh class, and presence of CSPH were no different between patients with or without VTE. A competitive-risk model focused on experiencing VTE and risk of death and bleeding as competing events showed no significant association between VTE and use of anticoagulant, Charlson comorbidity index, CSPH, male gender, HCC, length of hospitalization and Improve-VTE, Padua and MELD-Na scores. VTE is a rare event in patients with cirrhosis, occurring in only 1.6% of prospectively evaluated population, and no significant association between VTE and various risk factors was identified. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
34. Appropriateness of proton pump Inhibitor therapy in patients with cirrhosis: a retrospective study.
- Author
-
Santamorena, G., Pasta, A., Labanca, S., Marenco, S., Pieri, G., Torres, M.C. Plaz, and Giannini, E.G.
- Abstract
Proton pump inhibitors (PPIs) are commonly prescribed for gastroesophageal reflux disease (GERD) or prophylaxis of non-steroidal anti-inflammatory drugs and aspirin-induced gastric damage. However, their prolonged use in cirrhotic patients has been linked to complications like spontaneous bacterial peritonitis (SBP) and hepatic encephalopathy (EE). To evaluate the appropriateness of PPI therapy in patients with cirrhosis. We reviewed medical records of 209 cirrhotic patients admitted to our gastrointestinal ward (December 2021-December 2022). Demographics, clinical characteristics, PPI use indications, and incidence of EE and SBP were assessed. The median age was 69 years, and 74.4% were males. Main reasons for hospitalization were hepatocellular carcinoma (n=63, 28.7%), elective diagnostic-therapeutic procedures (n=63, 28.7%), non-liver-related events (n=54, 24.7%), and acute decompensation (n=39, 17.7%). Etiology of liver disease was alcohol in 91 patients (41.6%), virus-related in 77 (35.1%), and metabolic-associated in 30 (13.7%). The median MELD-Na score was 10 (8-14). At admission, 145 patients (66.2%) were on PPIs: of these, 42 patients (29.0%) had confirmed GERD, 12 (8.3%) had esophagitis ≥grade B, and 27 (18.6%) were on aspirin with bleeding risk-factors. Overall, inappropriate PPI use was observed in 74 patients (44.1%). Patients on PPIs were older, with higher MELD-Na and creatinine, and lower hemoglobin and Na compared to those not on PPIs (p<0.05). Multivariate analysis showed that PPI use was independently associated with older age (OR 1.03, IC95% 1.01-1.07) and lower hemoglobin (OR 0.82, IC95% 0.70-0.97). During a median follow-up of 18 months, the incidence of EE and SBP did not differ between PPI users and non-users. A significant proportion of patients with cirrhosis is inappropriately prescribed PPIs. Although this did not correlate with major liver-related events in the short term, proper PPI prescription education is crucial to prevent potential long-term consequences. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
35. Stackelberg problems with followers in the grand coalition of a Tu-game
- Author
-
Pensavalle, C. A. and Pieri, G.
- Published
- 2013
- Full Text
- View/download PDF
36. Joubert Syndrome: When to Suspect a Ciliopathy in a Patient with Liver Failure and Syndromic Phenotype
- Author
-
Rosti G, La Banca S, Pieri G, Trevisan L, Ruscitti F, Borro P, Mandich P, and Marenco S
- Subjects
Pathology ,medicine.medical_specialty ,Ciliopathy ,business.industry ,Liver failure ,Medicine ,Suspect ,business ,medicine.disease ,Phenotype ,Joubert syndrome - Published
- 2021
37. NAUTILOS - DU - Requirement No. 9
- Author
-
Pieri G., Furtado I., Cocco M., and Torres A.
- Subjects
Dual-use ,deliverable ,NAUTILOS - Abstract
In this document, following the details on the dual-use items in the sense of Regulation (EC) 428/2009, or other items for which an authorisation is needed, which has been included in the Grant Agreement, further details regarding the use of Unmanned Aerial Vehicle and Underwater Autonomous Vehicles that will be used in demonstrations, and their required authorisations is reported.
- Published
- 2021
38. New technology improves our understanding of changes in the marine environment
- Author
-
Pieri G., Ntoumas M., Martinelli M., Chatzinikolaou E., Martins F., Novellino A., Dimitrova N., Keller K., King A., Smerdon A., Mazza M., Malardé D., Cocco M., Torres A., Triantafyllou G., Sá S., João Bebianno M., Sparnocchia S., Kristiansen T., and Lusher A.
- Subjects
Sensors ,Ocean modelling ,Fisheries ,Samplers ,Data management ,Ocean observations - Abstract
Existing European observation tools and services have the potential to take advantage of cutting-edge technologies to obtain a wide range of data at a much higher spatial resolution and temporal regularity and duration. The EU-funded NAUTILOS project will develop a new generation of sensors and samplers for physical, chemical, and biological essential ocean variables in addition to micro- and nano-plastics. The project will improve our understanding of environmental variations and anthropogenic impacts connected with aquaculture, fisheries, and marine litter. The project will integrate recently advanced marine technologies into different observing platforms and deploy them through innovative and cost-effective methods in a wide range of key environmental settings and EU policy-related applications. The project aims to complement and expand existing European observation instruments and services and further enable and democratise the monitoring of the marine environment for both traditional and non-traditional data users.
- Published
- 2021
39. NAUTILOS - POPD - Requirement No. 2
- Author
-
Pieri G., Gianvincenzo A., Novellino A., and Deluca R.
- Subjects
Privacy code ,Personal data ,Information systems ,ComputingMilieux_LEGALASPECTSOFCOMPUTING ,GDPR - Abstract
This document is intended to provide recommendation on the procedures of the Information Systems and is inspired by the principles of correctness and diligence and is adopted in compliance with the provisions contained in the Privacy code and in the General Data Protection Regulation of the European Union.
- Published
- 2021
40. NAUTILOS - Data Management Plan
- Author
-
Novellino A., Colombo F., Gianvincenzo A. Pieri G., and Tampucci M.
- Subjects
Data Management Plan - Abstract
In this deliverable the Data Management Plan (DMP) of the project will be written, in compliance with the H2020 Data Management Guidelines, also based on inputs from WP8. It will outline a data management policy, including data to be generated by the project, their potential exploitation, curation and storage. Additionally, in line with the principles of Open Access to research data and publications generated through H2020 programmes, NAUTILOS will participate in the Open Research Data Pilot carried out by the European Commission.
- Published
- 2021
41. NAUTILOS - A - Requirement No. 3
- Author
-
Pieri G.
- Subjects
Ethics ,Animals ,Welfare - Abstract
This deliverable describes the general nature of the experiments with animals and the procedures that will be performed within NAUTILOS, in order to ensure animal welfare and adherence to EU Directive 2010/63/EU and the Three Rs guidelines principle. Moreover, information about existing expertise and experiences of the involved partners are reported.
- Published
- 2021
42. Image processing applied to temperature pattern identification
- Author
-
Papini O., Pieri G., and Reggiannini M.
- Subjects
Pattern Analysis ,Image Processing ,Sea Surface Temperature - Abstract
The objective of our work is to detect and classify mesoscale patterns in an upwelling ecosystem by analysing Sea Surface Temperature (SST) maps coming from satellite data. The poster shows how we organize this information in a "spaghetti plot", a tool that we use to analyse different trends of the SST in a target area for a period of time, and how we can associate those trends with different mesoscale patterns.
- Published
- 2021
43. NAUTILOS - EPQ - Requirement No. 5
- Author
-
Pieri G.
- Subjects
Ethics ,Health and safety procedures ,Environmental protection - Abstract
The deliverable presents and discusses the procedures and measures to mitigate environmental risks happening during the Project. Moreover, the application of health and safety procedures, conforming to the relevant guidelines and legislations are described, together with the measures minimising impact on endangered species or protected areas involved in the project activities.
- Published
- 2021
44. Special Issue 'Remote sensing for maritime and water monitoring'
- Author
-
Pieri G. and Reggiannini M.
- Subjects
Marine pollution monitoring ,Marine Information Systems ,Target classification ,Open water analysis ,Data representation ,Remote sensing ,Ocean observation ,GeneralLiterature_MISCELLANEOUS - Abstract
Remote sensing plays a crucial role in the supervision of extended maritime areas. In particular, multisensor multisource imagery is collected daily through satellite platforms moving on earth-centered orbits. This massive amount of data, including optical images and radar maps, can be exploited for relevant purposes, such as the implementation of maritime surveillance tasks. These tasks typically address security and safety issues (vessel traffic monitoring, search and rescue) as well as environmental sustainability aspects (fishery, pollution). Satellite missions also serve the purpose of remotely measuring meaningful properties of the water column (e.g., salinity, turbidity, pollutants concentration), enabling chemophysical surveys of maritime areas of interest. Publications in this Special Issue will aim at composing a comprehensive overview of the several aspects that emerge in the implementation of maritime observation platforms through data processing. With these topics in mind, among various other subjects, the authors are invited to discuss theoretical issues and methods concerning remote sensing and data processing over the marine and maritime environment (such as software platforms for surveillance or monitoring, processing algorithms for radar or optical imagery, sea-level assessment through satellite altimetry, integrated methods for the observation of the maritime environment, etc.), not excluding application case studies focused on remote sensing within the maritime context. To this purpose, authors are invited to submit contributions that take into consideration the following topics: Maritime data representation, analysis, and learning, Ocean observation applied to fishing sustainability or biodiversity, Techniques for data processing applied to maritime observation, Target detection, classification, and identification in maritime data, Marine pollution monitoring along with sea environment monitoring issues, Open water analysis and trends based on remote sensing.
- Published
- 2021
45. NAUTILOS - H - Requirement No. 1
- Author
-
Pieri G., Deluca R., and Chatzinikolaou E.
- Subjects
Ethics ,Deliverable ,informed consent ,Human participation ,humanities - Abstract
The procedures and criteria that will be used to identify/recruit research participants, as well as the informed consent procedures that will be implemented for the participation of humans external to NAUTILOS to the project activities and in regard to their data processing are presented in this document. Templates of the informed consent/assent forms and information sheets covering the voluntary participation and data protection issues, in the English version are provided.
- Published
- 2021
46. NAUTILOS - GEN - Requirement No. 13
- Author
-
Pieri G.
- Subjects
Deliverable ,Authorization - Abstract
This deliverable is relative to the Ethics Requirement n. 13 as a General requirement to keep copies of relevant authorisations for the usage of both Unmanned Aerial Vehicles (UAVs) and Underwater Autonomous Vehicles (AUVs). Those authorisations will be kept on file and made available to the EC Agency upon request.
- Published
- 2021
47. NAUTILOS - NEC - Requirement No. 4
- Author
-
Pieri G.
- Subjects
Ethics ,Non-EU countries - Abstract
This deliverable describes the ethical issues concerning the research performed outside the EU, both in terms of ethical compliance with EU standards, and in terms of the detail of the materials that will be imported/exported from and to non-EU countries to a member state.
- Published
- 2021
48. NAUTILOS - External advisory board report 1
- Author
-
Pieri G.
- Subjects
Environmental Management ,Advisory Board - Abstract
An annual report and evaluation provided by the External Advisory Board providing their overall assessment of NAUTILOS and advice on the future direction of the project. The following deliverable will be the report following their meeting after MM3 in M12.
- Published
- 2021
49. Smart parking systems: Reviewing the literature, architecture and ways forward
- Author
-
Biyik, C, Allam, Zaheer, Pieri, G, Moroni, D, O’fraifer, M, O’connell, E, Olariu, S, Khalid, M, Biyik, C, Allam, Zaheer, Pieri, G, Moroni, D, O’fraifer, M, O’connell, E, Olariu, S, and Khalid, M
- Abstract
The Internet of Things (IoT) has come of age, and complex solutions can now be imple-mented seamlessly within urban governance and management frameworks and processes. For cities, growing rates of car ownership are rendering parking availability a challenge and lowering the quality of life through increased carbon emissions. The development of smart parking solutions is thus necessary to reduce the time spent looking for parking and to reduce greenhouse gas emissions. The principal role of this research paper is to analyze smart parking solutions from a technical perspective, underlining the systems and sensors that are available, as documented in the literature. The review seeks to provide comprehensive insights into the building of smart parking solutions. A holistic survey of the current state of smart parking systems should incorporate the classification of such systems as big vehicular detection technologies. Finally, communication modules are presented with clarity.
- Published
- 2021
50. Pattern of macrovascular invasion in hepatocellular carcinoma
- Author
-
Guarino, Mariateresa, Cucchetti, A., Pontillo, G., Farinati, F., Benevento, F., Rapaccini, Gian Ludovico, Di Marco, Maria Teresa, Caturelli, E., Zoli, M., Rodolfo, S., Cabibbo, G., Marra, F., Mega, A., Gasbarrini, Antonio, Svegliati-Baroni, G., Foschi, F. G., Missale, G., Masotto, A., Nardone, G., Raimondo, G., Azzaroli, F., Vidili, G., Oliveri, F., Trevisani, F., Giannini, E. G., Morisco, F., Biselli, M., Caraceni, P., Garuti, F., Gramenzi, A., Neri, A., Rampoldi, D., Santi, V., Forgione, Alessandra, Granito, A., Muratori, L., Piscaglia, F., Sansone, V., Tovoli, F., Dajti, E., Marasco, G., Ravaioli, F., Cappelli, A., Golfieri, R., Mosconi, C., Renzulli, M., Cela, E. M., Facciorusso, A., Pelizzaro, F., Imondi, A., Sartori, A., Penzo, B., Cacciato, V., Casagrande, E., Moscatelli, A., Pellegatta, G., Pieri, G., De Matthaeis, Nicoletta, Allegrini, G., Lauria, V., Ghittoni, G., Pelecca, G., Chegai, F., Coratella, F., Ortenzi, M., Olivari, Elena Armida, Inno, A., Marchetti, F., Busacca, A., Camma, C., Di Martino, V., Rizzo, G. E. M., Franze, M. S., Saitta, C., Sauchella, A., Bevilacqua, V., Borghi, A., Gardini, A. C., Conti, Francesco, Berardinelli, D., Ercolani, G., Napoli, L., Campani, C., Di Bonaventura, C., Gitto, S., Coccoli, P., Malerba, A., Capasso, Monica, Fiorentino, Alice, Pignata, L., Cossiga, V., Romagnoli, V., Guarino M., Rapaccini G. L. (ORCID:0000-0002-6467-857X), Di Marco M., Gasbarrini A. (ORCID:0000-0002-7278-4823), Forgione A., de Matthaeis N., Olivari A., Conti F., Capasso M., Fiorentino A., Guarino, Mariateresa, Cucchetti, A., Pontillo, G., Farinati, F., Benevento, F., Rapaccini, Gian Ludovico, Di Marco, Maria Teresa, Caturelli, E., Zoli, M., Rodolfo, S., Cabibbo, G., Marra, F., Mega, A., Gasbarrini, Antonio, Svegliati-Baroni, G., Foschi, F. G., Missale, G., Masotto, A., Nardone, G., Raimondo, G., Azzaroli, F., Vidili, G., Oliveri, F., Trevisani, F., Giannini, E. G., Morisco, F., Biselli, M., Caraceni, P., Garuti, F., Gramenzi, A., Neri, A., Rampoldi, D., Santi, V., Forgione, Alessandra, Granito, A., Muratori, L., Piscaglia, F., Sansone, V., Tovoli, F., Dajti, E., Marasco, G., Ravaioli, F., Cappelli, A., Golfieri, R., Mosconi, C., Renzulli, M., Cela, E. M., Facciorusso, A., Pelizzaro, F., Imondi, A., Sartori, A., Penzo, B., Cacciato, V., Casagrande, E., Moscatelli, A., Pellegatta, G., Pieri, G., De Matthaeis, Nicoletta, Allegrini, G., Lauria, V., Ghittoni, G., Pelecca, G., Chegai, F., Coratella, F., Ortenzi, M., Olivari, Elena Armida, Inno, A., Marchetti, F., Busacca, A., Camma, C., Di Martino, V., Rizzo, G. E. M., Franze, M. S., Saitta, C., Sauchella, A., Bevilacqua, V., Borghi, A., Gardini, A. C., Conti, Francesco, Berardinelli, D., Ercolani, G., Napoli, L., Campani, C., Di Bonaventura, C., Gitto, S., Coccoli, P., Malerba, A., Capasso, Monica, Fiorentino, Alice, Pignata, L., Cossiga, V., Romagnoli, V., Guarino M., Rapaccini G. L. (ORCID:0000-0002-6467-857X), Di Marco M., Gasbarrini A. (ORCID:0000-0002-7278-4823), Forgione A., de Matthaeis N., Olivari A., Conti F., Capasso M., and Fiorentino A.
- Abstract
Background and aims: In patients with hepatocellular carcinoma (HCC), macrovascular invasion (MaVI) limits treatment options and decreases survival. Detailed data on the relationship between MaVI extension and patients' characteristics, and its impact on patients' outcome are limited. We evaluated the prevalence and extension of MaVI in a large cohort of consecutive HCC patients, analysing its association with liver disease and tumour characteristics, as well as with treatments performed and patients' survival. Methods: We analysed data of 4774 patients diagnosed with HCC recorded in the Italian Liver Cancer (ITA.LI.CA) database (2008-2018). Recursive partition analysis (RPA) was performed to evaluate interactions between MaVI, clinical variables and treatment, exploring the inter-relationship determining overall survival. Results: MaVI prevalence was 11.1%, and median survival of these patients was 6.0 months (95% CI, 5.1-7.1). MaVI was associated with younger age at diagnosis, presence of symptoms, worse Performance Status (PS) and liver function, high alphafetoprotein levels and large HCCs. MaVI extension was associated with worse PS, ascites and greater impairment in liver function. RPA identified patients' categories with different treatment indications and survival, ranging from 2.4 months in those with PS > 1 and ascites, regardless of MaVI extension (receiving best supportive care in 90.3% of cases), to 14.1 months in patients with PS 0-1, no ascites and Vp1-Vp2 MaVI (treated with surgery in 19.1% of cases). Conclusions: MaVI presence and extension, together with PS and ascites, significantly affect patients' survival and treatment selection. The decision tree based on these parameters may help assess patients' prognosis and inform therapeutic decisions.
- Published
- 2021
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.