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4. Cardiac remodelling – Part 1: From cells and tissues to circulating biomarkers. A review from the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology

Author

González, A, Richards, AM, de Boer, RA, Thum, T, Arfsten, H, Hülsmann, M, Falcao-Pires, I, Díez, J, Foo, RS, Chan, MYY, Aimo, A, Anene-Nzelu, GC, Abdelhamid, M, Adamopoulos, S, Anker, SD, Belenkov, Y, Gal, TB, Cohen-Solal, A, Böhm, M, Chioncel, O, Delgado, V, Emdin, M, Jankowska, EA, Gustafsson, F, Hill, L, Jaarsma, T, Januzzi, JL, Jhund, PS, Lopatin, Y, Lund, LH, Metra, M, Milicic, D, Moura, B, Mueller, C, Mullens, W, Núñez, J, Piepoli, MF, Rakisheva, A, Ristic, A, Rossignol, P, Savarese, G, Tocchetti, CG, Van Linthout, S, Volterrani, M, Seferovic, P, Rosano, G, Coats, AJ, and Bayes-Genis, A

Abstract

Cardiac remodelling refers to changes in left ventricular structure and function over time, with a progressive deterioration that may lead to heart failure (HF) development (adverse remodelling) or vice versa a recovery (reverse remodelling) in response to HF treatment. Adverse remodelling predicts a worse outcome, whilst reverse remodelling predicts a better prognosis. The geometry, systolic and diastolic function and electric activity of the left ventricle are affected, as well as the left atrium and on the long term even right heart chambers. At a cellular and molecular level, remodelling involves all components of cardiac tissue: cardiomyocytes, fibroblasts, endothelial cells and leucocytes. The molecular, cellular and histological signatures of remodelling may differ according to the cause and severity of cardiac damage, and clearly to the global trend toward worsening or recovery. These processes cannot be routinely evaluated through endomyocardial biopsies, but may be reflected by circulating levels of several biomarkers. Different classes of biomarkers (e.g. proteins, non-coding RNAs, metabolites and/or epigenetic modifications) and several biomarkers of each class might inform on some aspects on HF development, progression and long-term outcomes, but most have failed to enter clinical practice. This may be due to the biological complexity of remodelling, so that no single biomarker could provide great insight on remodelling when assessed alone. Another possible reason is a still incomplete understanding of the role of biomarkers in the pathophysiology of cardiac remodelling. Such role will be investigated in the first part of this review paper on biomarkers of cardiac remodelling.

Published
2022

5. Cardiac remodelling - Part 2: Clinical, imaging and laboratory findings. A review from the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology

Author

Aimo, A, Vergaro, G, Gonzalez, A, Barison, A, Lupon, J, Delgado, V, Richards, AM, de Boer, RA, Thum, T, Arfsten, H, Hulsmann, M, Falcao-Pires, I, Diez, J, Foo, RSY, Chan, MYY, Anene-Nzelu, CG, Abdelhamid, M, Adamopoulos, S, Anker, SD, Belenkov, Y, Gal, TB, Cohen-Solal, A, Bohm, M, Chioncel, O, Jankowska, EA, Gustafsson, F, Hill, L, Jaarsma, T, Januzzi, JL, Jhund, P, Lopatin, Y, Lund, LH, Metra, M, Milicic, D, Moura, B, Mueller, C, Mullens, W, Nunez, J, Piepoli, MF, Rakisheva, A, Ristic, AD, Rossignol, P, Savarese, G, Tocchetti, CG, van Linthout, S, Volterrani, M, Seferovic, P, Rosano, G, Coats, AJS, Emdin, M, and Bayes-Genis, A

Subjects
Ejection fraction, Predictors, Therapies, Remodelling, Heart failure, Biomarkers, Imaging
Abstract

In patients with heart failure, the beneficial effects of drug and device therapies counteract to some extent ongoing cardiac damage. According to the net balance between these two factors, cardiac geometry and function may improve (reverse remodelling, RR) and even completely normalize (remission), or vice versa progressively deteriorate (adverse remodelling, AR). RR or remission predict a better prognosis, while AR has been associated with worsening clinical status and outcomes. The remodelling process ultimately involves all cardiac chambers, but has been traditionally evaluated in terms of left ventricular volumes and ejection fraction. This is the second part of a review paper by the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology dedicated to ventricular remodelling. This document examines the proposed criteria to diagnose RR and AR, their prevalence and prognostic value, and the variables predicting remodelling in patients managed according to current guidelines. Much attention will be devoted to RR in patients with heart failure with reduced ejection fraction because most studies on cardiac remodelling focused on this setting.

Published
2022

6. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes

Author

Knuuti, Juhani, Wijns, William, Saraste, Antti, Capodanno, Davide, Barbato, Emanuele, Funck-Brentano, Christian, Prescott, Eva, Storey, Robert F, Deaton, Christi, Cuisset, Thomas, Agewall, Stefan, Dickstein, Kenneth, Edvardsen, Thor, Escaned, Javier, Gersh, Bernard J, Svitil, Pavel, Gilard, Martine, Hasdai, David, Hatala, Robert, Mahfoud, Felix, Masip, Josep, Muneretto, Claudio, Valgimigli, Marco, Achenbach, Stephan, Bax, Jeroen J, Neumann FJ, Sechtem U, Banning AP, Bonaros N, Bueno H, Bugiardini R, Chieffo A, Crea F, Czerny M, Delgado V, Dendale P, Flachskampf FA, Gohlke H, Grove EL, James S, Katritsis D, Landmesser U, Lettino M, Matter CM, Nathoe H, Niessner A, Patrono C, Petronio AS, Pettersen SE, Piccolo R, Piepoli MF, Popescu BA, Räber L, Richter DJ, Roffi M, Roithinger FX, Shlyakhto E, Sibbing D, Silber S, Simpson IA, Sousa-Uva M, Vardas P, Witkowski A, Zamorano JL, Achenbach S, Agewall S, Barbato E, Bax JJ, Capodanno D, Cuisset T, Deaton C, Dickstein K, Edvardsen T, Escaned J, Funck-Brentano C, Gersh BJ, Gilard M, Hasdai D, Hatala R, Mahfoud F, Masip J, Muneretto C, Prescott E, Saraste A, Storey RF, Svitil P, Valgimigli M, Windecker S, Aboyans V, Baigent C, Collet JP, Dean V, Fitzsimons D, Gale CP, Grobbee D, Halvorsen S, Hindricks G, Iung B, Jüni P, Katus HA, Leclercq C, Lewis BS, Merkely B, Mueller C, Petersen S, Touyz RM, Benkhedda S, Metzler B, Sujayeva V, Cosyns B, Kusljugic Z, Velchev V, Panayi G, Kala P, Haahr-Pedersen SA, Kabil H, Ainla T, Kaukonen T, Cayla G, Pagava Z, Woehrle J, Kanakakis J, Tóth K, Gudnason T, Peace A, Aronson D, Riccio C, Elezi S, Mirrakhimov E, Hansone S, Sarkis A, Babarskiene R, Beissel J, Maempel AJC, Revenco V, de Grooth GJ, Pejkov H, Juliebø V, Lipiec P, Santos J, Chioncel O, Duplyakov D, Bertelli L, Dikic AD, Studenčan M, Bunc M, Alfonso F, Bäck M, Zellweger M, Addad F, Yildirir A, Sirenko Y, Clapp B, Sorbonne Université (SU), Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Institute of cardiometabolism and nutrition (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Service de pharmacologie médicale [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Département de Cardiologie [Hôpital de la Timone - APHM], Hôpital de la Timone [CHU - APHM] (TIMONE)-Assistance Publique - Hôpitaux de Marseille (APHM), Knuuti, Juhani, Wijns, William, Saraste, Antti, Capodanno, Davide, Barbato, Emanuele, Funck-Brentano, Christian, Prescott, Eva, Storey, Robert F, Deaton, Christi, Cuisset, Thoma, Agewall, Stefan, Dickstein, Kenneth, Edvardsen, Thor, Escaned, Javier, Gersh, Bernard J, Svitil, Pavel, Gilard, Martine, Hasdai, David, Hatala, Robert, Mahfoud, Felix, Masip, Josep, Muneretto, Claudio, Valgimigli, Marco, Achenbach, Stephan, Bax, Jeroen J, Neumann FJ, Sechtem U, Banning AP, Bonaros N, Bueno H, Bugiardini R, Chieffo A, Crea F, Czerny M, Delgado V, Dendale P, Flachskampf FA, Gohlke H, Grove EL, James S, Katritsis D, Landmesser U, Lettino M, Matter CM, Nathoe H, Niessner A, Patrono C, Petronio AS, Pettersen SE, Piccolo R, Piepoli MF, Popescu BA, Räber L, Richter DJ, Roffi M, Roithinger FX, Shlyakhto E, Sibbing D, Silber S, Simpson IA, Sousa-Uva M, Vardas P, Witkowski A, Zamorano JL, Achenbach S, Agewall S, Barbato E, Bax JJ, Capodanno D, Cuisset T, Deaton C, Dickstein K, Edvardsen T, Escaned J, Funck-Brentano C, Gersh BJ, Gilard M, Hasdai D, Hatala R, Mahfoud F, Masip J, Muneretto C, Prescott E, Saraste A, Storey RF, Svitil P, Valgimigli M, Windecker S, Aboyans V, Baigent C, Collet JP, Dean V, Delgado V, Fitzsimons D, Gale CP, Grobbee D, Halvorsen S, Hindricks G, Iung B, Jüni P, Katus HA, Landmesser U, Leclercq C, Lettino M, Lewis BS, Merkely B, Mueller C, Petersen S, Petronio AS, Richter DJ, Roffi M, Shlyakhto E, Simpson IA, Sousa-Uva M, Touyz RM, Benkhedda S, Metzler B, Sujayeva V, Cosyns B, Kusljugic Z, Velchev V, Panayi G, Kala P, Haahr-Pedersen SA, Kabil H, Ainla T, Kaukonen T, Cayla G, Pagava Z, Woehrle J, Kanakakis J, Tóth K, Gudnason T, Peace A, Aronson D, Riccio C, Elezi S, Mirrakhimov E, Hansone S, Sarkis A, Babarskiene R, Beissel J, Maempel AJC, Revenco V, de Grooth GJ, Pejkov H, Juliebø V, Lipiec P, Santos J, Chioncel O, Duplyakov D, Bertelli L, Dikic AD, Studenčan M, Bunc M, Alfonso F, Bäck M, Zellweger M, Addad F, Yildirir A, Sirenko Y, Clapp B, Clinical sciences, Cardio-vascular diseases, Cardiology, Knuuti, Juhani [0000-0003-3156-9593], Apollo - University of Cambridge Repository, Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases (ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut de Cardiométabolisme et Nutrition = Institute of Cardiometabolism and Nutrition [CHU Pitié Salpêtrière] (IHU ICAN), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), University of Zurich, Knuuti, J., Wijns, W., Achenbach, S., Agewall, S., Barbato, E., Bax, J. J., Capodanno, D., Cuisset, T., Deaton, C., Dickstein, K., Edvardsen, T., Escaned, J., Funck-Brentano, C., Gersh, B. J., Gilard, M., Hasdai, D., Hatala, R., Mahfoud, F., Masip, J., Muneretto, C., Prescott, E., Saraste, A., Storey, R. F., Svitil, P., Valgimigli, M., Windecker, S., Aboyans, V., Baigent, C., Collet, J. -P., Dean, V., Delgado, V., Fitzsimons, D., Gale, C. P., Grobbee, D. E., Halvorsen, S., Hindricks, G., Iung, B., Juni, P., Katus, H. A., Landmesser, U., Leclercq, C., Lettino, M., Lewis, B. S., Merkely, B., Mueller, C., Petersen, S., Petronio, A. S., Richter, D. J., Roffi, M., Shlyakhto, E., Simpson, I. A., Sousa-Uva, M., Touyz, R. M., Benkhedda, S., Metzler, B., Sujayeva, V., Cosyns, B., Kusljugic, Z., Velchev, V., Panayi, G., Kala, P., Haahr-Pedersen, S. A., Kabil, H., Ainla, T., Kaukonen, T., Cayla, G., Pagava, Z., Woehrle, J., Kanakakis, J., Toth, K., Gudnason, T., Peace, A., Aronson, D., Riccio, C., Elezi, S., Mirrakhimov, E., Hansone, S., Sarkis, A., Babarskiene, R., Beissel, J., Cassar Maempel, A. J., Revenco, V., de Grooth, G. J., Pejkov, H., Juliebo, V., Lipiec, P., Santos, J., Chioncel, O., Duplyakov, D., Bertelli, L., Dikic, A. D., Studencan, M., Bunc, M., Alfonso, F., Back, M., Zellweger, M., Addad, F., Yildirir, A., Sirenko, Y., and Clapp, B.

Subjects
anti-ischaemic drug, chronic coronary syndromes, medicine.medical_treatment, [SDV]Life Sciences [q-bio], lipid-lowering drugs, Diagnostic Techniques, Cardiovascular, antithrombotic therapy, Disease, 030204 cardiovascular system & hematology, Guideline, Coronary artery disease, 0302 clinical medicine, Disease management (health), Societies, Medical, ComputingMilieux_MISCELLANEOUS, chronic coronary syndrome, angina pectori, Disease Management, food and beverages, imaging, risk assessment, Syndrome, 3. Good health, Natural history, Europe, Cardiology, Cardiology and Cardiovascular Medicine, coronary artery disease, medicine.medical_specialty, lifestyle modifications, anti-ischaemic drugs, Ischemia, 610 Medicine & health, vasospastic angina, Guidelines, Revascularization, diagnostic testing, 11171 Cardiocentro Ticino, 2705 Cardiology and Cardiovascular Medicine, 03 medical and health sciences, angina pectoris, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Internal medicine, medicine, Journal Article, Humans, business.industry, screening, fungi, 030229 sport sciences, medicine.disease, lipid-lowering drug, Angina pectoris, Anti-ischaemic drugs, Antithrombotic therapy, Chronic coronary syndromes, Diagnostic testing, Imaging, Lifestyle modifications, Lipid-lowering drugs, Microvascular angina, Myocardial ischaemia, Myocardial revascularization, Risk assessment, Screening, Vasospastic angina, myocardial ischaemia, myocardial revascularization, Heart failure, microvascular angina, Chronic Disease, Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, lifestyle modification, Coronary Artery Disease/diagnosis, business, Fibrinolytic agent
Abstract

Coronary artery disease (CAD) is a pathological process characterized by atherosclerotic plaque accumulation in the epicardial arteries, whether obstructive or non-obstructive. This process can be modified by lifestyle adjustments, pharmacological therapies, and invasive interventions designed to achieve disease stabilization or regression. The disease can have long, stable periods but can also become unstable at any time, typically due to an acute atherothrombotic event caused by plaque rupture or erosion. However, the disease is chronic, most often progressive, and hence serious, even in clinically apparently silent periods. The dynamic nature of the CAD process results in various clinical presentations, which can be conveniently categorized as either acute coronary syndromes (ACS) or chronic coronary syndromes (CCS). The Guidelines presented here refer to the management of patients with CCS. The natural history of CCS is illustrated in Figure 1.

Published
2019

7. Factors associated with lack of improvement in submaximal exercise capacity of patients with heart failure

Author

Jaarsma, T, Perkio Kato, N, Ben Gal, T, Back, M, Chiala, O, Evangelista, L, Martensson, J, Piepoli, Mf, Vellone, E, Klompstra, L, Stromberg, A, Ben Avraham, B, Boyne, J, Hagenow, A, and Hagglund, E

Subjects
Male, Submaximal exercise capacity, medicine.medical_specialty, Psychological intervention, Walk Test, Heart failure, Cardiorespiratory Medicine and Haematology, Cardiovascular, 6&nbsp, 6 min walk test, Physical activity, chemistry.chemical_compound, Clinical Research, medicine, Diseases of the circulatory (Cardiovascular) system, Humans, Aerobic exercise, Sjukgymnastik, Physiotherapy, Aged, Heart Failure, Creatinine, Exercise Tolerance, business.industry, 6 min walk test, HF-Wii study team, Cognition, Original Articles, Odds ratio, Prognosis, medicine.disease, Confidence interval, Exercise Therapy, Settore MED/45, Heart Disease, chemistry, RC666-701, Physical therapy, Anxiety, min walk test, Original Article, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, business
Abstract

Aims Improvement in exercise capacity is the primary goal of physical activity programmes for patients with heart failure (HF). Although activity programmes are effective for some patients, others do not benefit. Identifying factors related to a lack of improvement in submaximal exercise capacity may help us interpret findings and design new interventions. The aim of this study is to identify factors contributing to a lack of improvement in submaximal exercise capacity 3 months after physical activity advice or an exergame intervention in patients with HF. Additionally, we aimed to assess differences in lack of improvement in submaximal exercise capacity of patients whose baseline exercise capacity predicted a worse compared with better prognosis of HF. Methods and results This secondary analysis of the HF-Wii study analysed baseline and 3 month data of the 6 min walk test (6MWT) from 480 patients (mean age 67 years, 72% male). Data were analysed separately in patients with a pre-defined 6 min walking distance at baseline of = 300 m (n = 401). Among patients with a baseline 6MWT of >= 300 m, 18% had deteriorated submaximal exercise capacity. In the multiple logistic regression analysis, lower baseline levels of self-reported physical activity [odds ratio (OR) = 0.77, 95% confidence interval (CI) = 0.60-0.97], lower baseline levels of cognitive function (OR = 0.87, 95%CI = 0.79-0.96) were significantly associated with lack of improvement in exercise capacity at 3 months. Not randomized to exergaming (OR = 0.63, 95%CI = 0.37-1.09) was likely (P = 0.097) to be associated with lack of improvement in exercise capacity at 3 months. Among the 79 patients with baseline 6MWT of Funding Agencies|Swedish National Science Council [K2013-69X-22302-01-3, 2016-01390]; Swedish National Science Council/the Swedish Research Council for Health, Working Life and Welfare, VR-FORTE [2014-4100]; Swedish Heart and Lung AssociationSwedish Heart-Lung Foundation [E085/12]; Swedish Heart and Lung FoundationSwedish Heart-Lung Foundation [20130340, 20160439]; Vardal Foundation [2014-0018]; Medical Research Council of Southeast SwedenUK Research & Innovation (UKRI)Medical Research Council UK (MRC) [FORSS 474681]

Published
2021

8. Association between loop diuretic dose changes and outcomes in chronic heart failure: observations from the ESC-EORP Heart Failure Long-Term Registry

Author

Kapelios, CJ, Laroche, C, Crespo-Leiro, MG, Anker, SD, Coats, AJS, Díaz-Molina, B, Filippatos, G, Lainscak, M, Maggioni, AP, McDonagh, T, Mebazaa, A, Metra, M, Moura, B, Mullens, W, Piepoli, MF, Rosano, GMC, Ruschitzka, F, Seferovic, PM, Lund, LH, and Heart Failure Long-Term Registry Investigators Group

Abstract

AIMS: Guidelines recommend down-titration of loop diuretics (LD) once euvolaemia is achieved. In outpatients with heart failure (HF), we investigated LD dose changes in daily cardiology practice, agreement with guideline recommendations, predictors of successful LD down-titration and association between dose changes and outcomes. METHODS AND RESULTS: We included 8130 HF patients from the ESC-EORP Heart Failure Long-Term Registry. Among patients who had dose decreased, successful decrease was defined as the decrease not followed by death, HF hospitalization, New York Heart Association class deterioration, or subsequent increase in LD dose. Mean age was 66 ± 13 years, 71% men, 62% HF with reduced ejection fraction, 19% HF with mid-range ejection fraction, 19% HF with preserved ejection fraction. Median [interquartile range (IQR)] LD dose was 40 (25-80) mg. LD dose was increased in 16%, decreased in 8.3% and unchanged in 76%. Median (IQR) follow-up was 372 (363-419) days. Diuretic dose increase (vs. no change) was associated with HF death [hazard ratio (HR) 1.53, 95% confidence interval (CI) 1.12-2.08; P = 0.008] and nominally with cardiovascular death (HR 1.25, 95% CI 0.96-1.63; P = 0.103). Decrease of diuretic dose (vs. no change) was associated with nominally lower HF (HR 0.59, 95% CI 0.33-1.07; P = 0.083) and cardiovascular mortality (HR 0.62, 95% CI 0.38-1.00; P = 0.052). Among patients who had LD dose decreased, systolic blood pressure [odds ratio (OR) 1.11 per 10 mmHg increase, 95% CI 1.01-1.22; P = 0.032], and absence of (i) sleep apnoea (OR 0.24, 95% CI 0.09-0.69; P = 0.008), (ii) peripheral congestion (OR 0.48, 95% CI 0.29-0.80; P = 0.005), and (iii) moderate/severe mitral regurgitation (OR 0.57, 95% CI 0.37-0.87; P = 0.008) were independently associated with successful decrease. CONCLUSION: Diuretic dose was unchanged in 76% and decreased in 8.3% of outpatients with chronic HF. LD dose increase was associated with worse outcomes, while the LD dose decrease group showed a trend for better outcomes compared with the no-change group. Higher systolic blood pressure, and absence of (i) sleep apnoea, (ii) peripheral congestion, and (iii) moderate/severe mitral regurgitation were independently associated with successful dose decrease.

Published
2020

9. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS)

Author

Mach, F, Baigent, C, Catapano, AL, Koskinas, KC, Casula, M, Badimon, L, Chapman, MJ, De Backer, GG, Delgado, V, Ference, BA, Graham, IM, Halliday, A, Landmesser, U, Mihaylova, B, Pedersen, TR, Riccardi, G, Richter, DJ, Sabatine, MS, Taskinen, MR, Tokgozoglu, L, Wiklund, O, Mueller, C, Drexel, H, Aboyans, V, Corsini, A, Doehner, W, Farnier, M, Gigante, B, Kayikcioglu, M, Krstacic, G, Lambrinou, E, Lewis, BS, Masip, J, Moulin, P, Petersen, S, Petronio, AS, Piepoli, MF, Pinto, X, Raber, L, Ray, KK, Reiner, Z, Riesen, WF, Roffi, M, Schmid, JP, Shlyakhto, E, Simpson, IA, Stroes, E, Sudano, I, Tselepis, AD, Viigimaa, M, Vindis, C, Vonbank, A, Vrablik, M, Vrsalovic, M, Gomez, JLZ, Collet, JP, European Soc Cardiology, and European Atherosclerosis Soc

Subjects
high-density lipoproteins, lipoprotein remnants, dyslipidaemias, cholesterol, treatment (drugs), very low-density lipoproteins, Guidelines, treatment (lifestyle), treatment (adherence), lipoprotein(a), total cardiovascular risk, low-density lipoproteins, familial hypercholesterolaemia, apolipoprotein B, triglycerides
Published
2020

12. 2016 European Guidelines on cardiovascular disease prevention in clinical practice The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR)

Author

Piepoli MF, Hoes AW, Agewall S, Albus C, Brotons C, Catapano AL, Cooney MT, Corrà U, Cosyns B, Deaton C, Graham I, Hall MS, Hobbs FDR, Løchen ML, Löllgen H, Marques-Vidal P, Perk J, Prescott E, Redon J, Richter DJ, Sattar N, Smulders Y, Tiberi M, van der Worp HB, van Dis I, Verschuren WMM1, Binno S, De Backer G, Roffi M, Aboyans V, Bachl N, Bueno H, Carerj S, Cho L, Cox J, De Sutter J, Egidi G, Fisher M, Fitzsimons D, Franco OH, Guenoun M, Jennings C, Jug B, Kirchhof P, Kotseva K, Lip GY, Mach F, Mancia G, Bermudo FM, Mezzani A, Niessner A, Ponikowski P, Rauch B, Rydén L, Stauder A, Turc G, Wiklund O, Windecker S, Zamorano JL, Achenbach S, Badimon L, Barón-Esquivias G, Baumgartner H, Bax JJ, Dean V, Erol Ç, Gaemperli O, Kolh P, Lancellotti P, Nihoyannopoulos P, Torbicki A, Vaz Carneiro A, Metzler B, Najafov R, Stelmashok V, De Maeyer C, Dilic M, Gruev I, Milicic D, Vaverkova H, Gustafsson I, Attia I, Duishvili D, Kostova N, Ferrières J, Klimiashvili Z, Hambrecht R, Tsioufis K, Szabados E, Andersen K, Vaughan C, Zafrir B, Novo S, Davletov K, Jashari F, Kerimkulova A, Mintale I, Saade G, Petrulioniene Z, Delagardelle C, Magri CJ, Rudi V, Oukerraj L, Çölkesen BE, Schirmer H, Jankowski P, Dos Reis RP, Gherasim D, Nedogoda S, Zavatta M, Giga V, Filipova S, Padial LR, Kiessling A, Mahdhaoui A, Ural D, Nesukay E, Gale C., Internal medicine, ICaR - Circulation and metabolism, Piepoli MF, Hoes AW, Agewall S, Albus C, Brotons C, Catapano AL, Cooney MT, Corrà U, Cosyns B, Deaton C, Graham I, Hall MS, Hobbs FDR, Løchen ML, Löllgen H, Marques-Vidal P, Perk J, Prescott E, Redon J, Richter DJ, Sattar N, Smulders Y, Tiberi M, van der Worp HB, van Dis I, Verschuren WMM1, Binno S, De Backer G, Roffi M, Aboyans V, Bachl N, Bueno H, Carerj S, Cho L, Cox J, De Sutter J, Egidi G, Fisher M, Fitzsimons D, Franco OH, Guenoun M, Jennings C, Jug B, Kirchhof P, Kotseva K, Lip GY, Mach F, Mancia G, Bermudo FM, Mezzani A, Niessner A, Ponikowski P, Rauch B, Rydén L, Stauder A, Turc G, Wiklund O, Windecker S, Zamorano JL, Zamorano JL, Aboyans V, Achenbach S, Agewall S, Badimon L, Barón-Esquivias G, Baumgartner H, Bax JJ, Bueno H, Carerj S, Dean V, Erol Ç, Fitzsimons D, Gaemperli O, Kirchhof P, Kolh P, Lancellotti P, Lip GY, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Roffi M, Torbicki A, Vaz Carneiro A, Windecker S, Metzler B, Najafov R, Stelmashok V, De Maeyer C, Dilic M, Gruev I, Milicic D, Vaverkova H, Gustafsson I, Attia I, Duishvili D, Kostova N, Ferrières J, Klimiashvili Z, Hambrecht R, Tsioufis K, Szabados E, Andersen K, Vaughan C, Zafrir B, Novo S, Davletov K, Jashari F, Kerimkulova A, Mintale I, Saade G, Petrulioniene Z, Delagardelle C, Magri CJ, Rudi V, Oukerraj L, Çölkesen BE, Schirmer H, Jankowski P, Dos Reis RP, Gherasim D, Nedogoda S, Zavatta M, Giga V, Filipova S, Padial LR, Kiessling A, Mach F, Mahdhaoui A, Ural D, Nesukay E, Gale C., Cardio-vascular diseases, and Clinical sciences

Subjects
Cost-Benefit Analysis, General Practice, 030204 cardiovascular system & hematology, Guideline, Diabete, 0302 clinical medicine, Hyperlipidemia, Stakeholder, Medicine, 030212 general & internal medicine, Multiple Chronic Conditions, Practice Patterns, Physicians', Societies, Medical, Risk assessment, education.field_of_study, Cardiac Rehabilitation, Diabetes, Rehabilitation, Smoking, Psychosocial factor, Age Factors, Lipid, Middle Aged, Primary care, Pedigree, Europe, Cardiovascular Diseases, Psychosocial factors, Hypertension, Blood pressure, Diet, Healthy, Cardiology and Cardiovascular Medicine, Adult, Diagnostic Imaging, medicine.medical_specialty, Ambulatory blood pressure, Population, Cardiology, Healthy lifestyle, Hyperlipidemias, Health Promotion, Diabetic angiopathy, Guidelines, Risk Assessment, 03 medical and health sciences, Sex Factors, Diabetes mellitus, Journal Article, Humans, Clinical settings, Healthy Lifestyle, Intensive care medicine, education, Exercise, Antihypertensive Agents, Nutrition, Aged, business.industry, Vascular disease, Physical activity, Prevention, medicine.disease, body regions, Clinical setting, Risk management, Socioeconomic Factors, Smoking Cessation, Joint Esc Guidelines, business, Biomarkers, Diabetic Angiopathies
Abstract

ABI : ankle–brachial (blood pressure) index ABPM : ambulatory blood pressure monitoring ACCORD : Action to Control Cardiovascular Risk in Diabetes ACE-I : angiotensin-converting enzyme inhibitor ACS : acute coronary syndromes ADVANCE : Action in Diabetes and Vascular disease: PreterAx

Published
2016

13. 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy

Author

Regitz-Zagrosek, V, Roos-Hesselink, JW, Bauersachs, J, Blomström-Lundqvist, C, Cífková, R, De Bonis, M, Iung, B, Johnson, MR, Kintscher, U, Kranke, P, Lang, IM, Morais, J, Pieper, PG, Presbitero, P, Price, S, Rosano, GMC, Seeland, U, Simoncini, T, Swan, L, Warnes, CA, Deaton, C, Simpson, IA, Aboyans, V, Agewall, S, Barbato, E, Calda, P, Coca, A, Coman, IM, De Backer, J, Delgado, V, Di Salvo, G, Fitzsimmons, S, Fitzsimons, D, Garbi, M, Gevaert, S, Hindricks, G, Jondeau, G, Kluin, J, Lionis, C, McDonagh, TA, Meier, P, Moons, P, Pantazis, A, Piepoli, MF, Rocca, B, Roffi, M, Rosenkranz, S, Sarkozy, A, Shlyakhto, E, Silversides, CK, Sliwa, K, Sousa-Uva, M, Tamargo, J, Thorne, S, Van de Velde, M, Williams, B, Zamorano, JL, Windecker, S, Bueno, H, Collet, J-P, Dean, V, Gaemperli, O, Jüni, P, Katus, HA, Knuuti, J, Lancellotti, P, Leclercq, C, Ponikowski, P, Richter, DJ, Hammoudi, N, Piruzyan, A, Mascherbauer, J, Samadov, F, Prystrom, A, Pasquet, A, Caluk, J, Gotcheva, N, Skoric, B, Heracleous, H, Vejlstrup, N, Maser, M, Kaaja, RJ, Srbinovska-Kostovska, E, Mounier-Vehier, C, Vakhtangadze, T, Rybak, K, Giannakoulas, G, Kiss, RG, Thrainsdottir, IS, Erwin, RJ, Porter, A, Geraci, G, Ibrahimi, P, Lunegova, O, Mintale, I, Kadri, Z, Benlamin, H, Barysiene, J, Banu, CA, Caruana, M, Gratii, C, Haddour, L, Bouma, BJ, Estensen, M-E, Hoffman, P, Petris, AO, Moiseeva, O, Bertelli, L, Tesic, BV, Dubrava, J, Koželj, M, Prieto-Arévalo, R, Furenäs, E, Schwerzmann, M, Mourali, MS, Ozer, N, Mitchenko, O, Nelson-Piercy, C, Regitz-Zagrosek, V., Roos-Hesselink, J. W., Bauersachs, J., Blomstrom-Lundqvist, C., Cifkova, R., De Bonis, M., Iung, B., Johnson, M. R., Kintscher, U., Kranke, P., Lang, I. M., Morais, J., Pieper, P. G., Presbitero, P., Price, S., Rosano, G. M. C., Seeland, U., Simoncini, T., Swan, L., Warnes, C. A., Regitz-Zagrosek, Vera, Roos-Hesselink, Jolien W, Bauersachs, Johann, Blomström-Lundqvist, Carina, Cífková, Renata, De Bonis, Michele, Iung, Bernard, Johnson, Mark Richard, Kintscher, Ulrich, Kranke, Peter, Lang, Irene Marthe, Morais, Joao, Pieper, Petronella G, Presbitero, Patrizia, Price, Susanna, Rosano, Giuseppe MC, Seeland, Ute, Simoncini, Tommaso, Swan, Lorna, Warnes, Carole A, and Cardiology

Subjects
Counseling, Prenatal Diagnosi, 030204 cardiovascular system & hematology, Guideline, Cardiovascular, 0302 clinical medicine, Pregnancy, Prenatal Diagnosis, 030212 general & internal medicine, 1102 Cardiorespiratory Medicine and Haematology, Societies, Medical, Risk assessment, Advisory Committee, Advisory Committees, Cardiology, Cardiovascular Agents, Europe, Female, Humans, Poland, Pregnancy Complications, Cardiovascular, Practice Guidelines as Topic, valvular heart disease, Cardiovascular disease, Management, Hypertension, Drug therapy, Cardiology and Cardiovascular Medicine, Arrhythmia, Human, medicine.medical_specialty, Settore BIO/14 - FARMACOLOGIA, Cardiomyopathy, Heart failure, Cardiovascular therapy, Pulmonary hypertension, Aortic pathology, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Medical, medicine, Cardiovascular diagnosis, Intensive care medicine, Congenital heart disease, Pharmacology, business.industry, ta3121, medicine.disease, Valvular heart disease, Pregnancy Complications, Cardiovascular System & Hematology, Cardiovascular Agent, Societies, business
Published
2019

14. 2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM)

Author

Habib, G, Lancellotti, P, Antunes, Mj, Bongiorni, Mg, Casalta, Jp, Del Zotti, F, Dulgheru, R, El Khoury, G, Erba, Pa, Iung, B, Miro, Jm, Mulder, Bj, Plonska-Gosciniak, E, Price, S, Roos-Hesselink, J, Snygg-Martin, U, Thuny, F, Tornos Mas, P, Vilacosta, I, Zamorano, Jl, Document, Reviewers., Erol, Ç, Nihoyannopoulos, P, Aboyans, V, Agewall, S, Athanassopoulos, G, Aytekin, S, Benzer, W, Bueno, H, Broekhuizen, L, Carerj, S, Cosyns, B, De Backer, J, De Bonis, M, Dimopoulos, K, Donal, E, Drexel, H, Flachskampf, Fa, Hall, R, Halvorsen, S, Hoen, B, Kirchhof, P, Lainscak, M, Leite-Moreira, Af, Lip, Gy, Mestres, Ca, Piepoli, Mf, Punjabi, Pp, Rapezzi, C, Rosenhek, R, Siebens, K, Tamargo, J, Walker, Dm, Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F, Dulgheru R, El Khoury G, Erba PA, Iung B, Miro JM, Mulder BJ, Plonska-Gosciniak E, Price S, Roos-Hesselink J, Snygg-Martin U, Thuny F, Tornos Mas P, Vilacosta I, Zamorano JL, Document Reviewers., Erol Ç, Nihoyannopoulos P, Aboyans V, Agewall S, Athanassopoulos G, Aytekin S, Benzer W, Bueno H, Broekhuizen L, Carerj S, Cosyns B, De Backer J, De Bonis M, Dimopoulos K, Donal E, Drexel H, Flachskampf FA, Hall R, Halvorsen S, Hoen B, Kirchhof P, Lainscak M, Leite-Moreira AF, Lip GY, Mestres CA, Piepoli MF, Punjabi PP, Rapezzi C, Rosenhek R, Siebens K, Tamargo J, Walker DM, DIPARTIMENTO DI MEDICINA SPECIALISTICA, DIAGNOSTICA E SPERIMENTALE, Facolta' di MEDICINA e CHIRURGIA, AREA MIN. 06 - Scienze mediche, Habib, G, Lancellotti, P, Antunes, Mj, Bongiorni, Mg, Casalta, Jp, Del Zotti, F, Dulgheru, R, El Khoury, G, Erba, Pa, Iung, B, Miro, Jm, Mulder, Bj, Plonska gosciniak, E, Price, S, Roos hesselink, J, Snygg martin, U, Thuny, F, Mas, Pt, Vilacosta, I, Zamorano, Jl, Erol, Ç, Nihoyannopoulos, P, Aboyans, V, Agewall, S, Athanassopoulos, G, Aytekin, S, Benzer, W, Bueno, H, Broekhuizen, L, Carerj, S, Cosyns, B, De Backer, J, DE BONIS, Michele, Dimopoulos, K, Donal, E, Drexel, H, Flachskampf, Fa, Hall, R, Halvorsen, S, Hoen, B, Kirchhof, P, Lainscak, M, Leite moreira, Af, Lip, Gy, Mestres, Ca, Piepoli, Mf, Punjabi, Pp, Rapezzi, C, Rosenhek, R, Siebens, K, Tamargo, J, and Walker, Dm

Subjects
Microbiological Techniques, Heart disease, Embolism, Heart Valve Diseases, Cardiac device, Cardiac imaging, Cardiac surgery, Congenital heart disease, Echocardiography, Endocarditis, Guidelines, Infection, Nuclear imaging, Pregnancy, Prevention, Prognosis, Prophylaxis, Prosthetic heart valves, Valve disease, Guideline, Arrhythmias, Cardiovascular, Congenital, Postoperative Complications, Recurrence, Risk Factors, Neoplasms, Ambulatory Care, Non-Infective, Pericarditis, Endocarditi, Musculoskeletal Diseases, Prophylaxi, Heart Defects, Cross Infection, Acute Kidney Injury, Operative, Anti-Bacterial Agents, Myocarditis, Prosthetic heart valve, Endocarditis, Non-Infective, Infective endocarditis, Cardiology, Female, Cardiology and Cardiovascular Medicine, Infected, Cardiac, Heart Defects, Congenital, Diagnostic Imaging, medicine.medical_specialty, Prosthesis-Related Infections, Critical Care, Prognosi, Pregnancy Complications, Cardiovascular, Risk Assessment, NO, Aneurysm, Infected, Antibiotic Prophylaxis, Arrhythmias, Cardiac, Clinical Laboratory Techniques, Dentistry, Operative, Fibrinolytic Agents, Heart Failure, Humans, Long-Term Care, Nervous System Diseases, Patient Care Team, Splenic Diseases, Thoracic Surgical Procedures, Internal medicine, medicine, business.industry, medicine.disease, Aneurysm, Pregnancy Complications, Heart failure, Dentistry, business, Fibrinolytic agent
Abstract

none 53 si The disclosure forms of all experts involved in the development of these guidelines are available on the ESC website http://www.escardio.org/guidelines. Representing the European Association of Nuclear Medicine (EANM); Representing the European Society of Clinical Microbiology and Infectious Diseases (ESCMID); and Representing the European Association for Cardio-Thoracic Surgery (EACTS). Guidelines for the management of infective endocarditis Habib G; Lancellotti P; Antunes MJ; Bongiorni MG; Casalta JP; Del Zotti F; Dulgheru R; El Khoury G; Erba PA; Iung B; Miro JM; Mulder BJ; Plonska-Gosciniak E; Price S; Roos-Hesselink J; Snygg-Martin U; Thuny F; Tornos Mas P; Vilacosta I; Zamorano JL; Document Reviewers.; Erol Ç; Nihoyannopoulos P; Aboyans V; Agewall S; Athanassopoulos G; Aytekin S; Benzer W; Bueno H; Broekhuizen L; Carerj S; Cosyns B; De Backer J; De Bonis M; Dimopoulos K; Donal E; Drexel H; Flachskampf FA; Hall R; Halvorsen S; Hoen B; Kirchhof P; Lainscak M; Leite-Moreira AF; Lip GY; Mestres CA; Piepoli MF; Punjabi PP; Rapezzi C; Rosenhek R; Siebens K; Tamargo J; Walker DM Habib G; Lancellotti P; Antunes MJ; Bongiorni MG; Casalta JP; Del Zotti F; Dulgheru R; El Khoury G; Erba PA; Iung B; Miro JM; Mulder BJ; Plonska-Gosciniak E; Price S; Roos-Hesselink J; Snygg-Martin U; Thuny F; Tornos Mas P; Vilacosta I; Zamorano JL; Document Reviewers.; Erol Ç; Nihoyannopoulos P; Aboyans V; Agewall S; Athanassopoulos G; Aytekin S; Benzer W; Bueno H; Broekhuizen L; Carerj S; Cosyns B; De Backer J; De Bonis M; Dimopoulos K; Donal E; Drexel H; Flachskampf FA; Hall R; Halvorsen S; Hoen B; Kirchhof P; Lainscak M; Leite-Moreira AF; Lip GY; Mestres CA; Piepoli MF; Punjabi PP; Rapezzi C; Rosenhek R; Siebens K; Tamargo J; Walker DM

Published
2015

15. 2015 ESC Guidelines for the diagnosis and management of pericardial diseases: The Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC)Endorsed by: The European Association for Cardio-Thoracic Surgery (EACTS)

Author

Adler Y, Charron P, Imazio M, Badano L, Barón-Esquivias G, Bogaert J, Brucato A, Gueret P, Klingel K, Lionis C, Maisch B, Mayosi B, Pavie A, Ristic AD, Sabaté Tenas M, Seferovic P, Swedberg K, Tomkowski W, Achenbach S, Agewall S, Al-Attar N, Angel Ferrer J, Arad M, Asteggiano R, Bueno H, Caforio ALP, Carerj S, Ceconi C, Evangelista A, Flachskampf F, Giannakoulas G, Gielen S, Habib G, Kolh P, Lambrinou E, Lancellotti P, Lazaros G, Linhart A, Meurin P, Nieman K, Piepoli MF, Price S, Roos-Hesselink J, Roubille F, Ruschitzka F, Sagristà Sauleda J, Sousa-Uva M, Uwe Voigt J, Luis Zamorano J, Zamorano JL, Aboyans V, Badimon L, Baumgartner H, Bax JJ, Dean V, Erol Ç, Fitzimons D, Gaemperli O, Kirchhof P, Lip GY, Nihoyannopoulos P, Ponikowski P, Roffi M, Torbicki A, Vaz Carneiro A, Windecker S, Shuka N, Sisakian H, Mascherbauer J, Isayev E, Shumavets V, Van Camp G, Gatzov P, Hanzevacki JS, Moustra HH, Møller JE, Aboleineen MW, Põder P, Lehtonen J, Antov S, Damy T, Schieffer B, Dimitriadis K, Kiss RG, Rafnsson A, Novo S, Mirrakhimov E, Stradinš P, Kavoliuniene A, Codreanu A, Dingli P, Vataman E, El Hattaoui M, Samstad SO, Hoffman P, Lopes LR, Dimulescu DR, Arutyunov GP, Pavlovic M, Dúbrava J, Sauleda JS, Andersson B, Müller H, Bouma BJ, Abaci A, Archbold A, Nesukay E, and Adler Y, Charron P, Imazio M, Badano L, Barón-Esquivias G, Bogaert J, Brucato A, Gueret P, Klingel K, Lionis C, Maisch B, Mayosi B, Pavie A, Ristic AD, Sabaté Tenas M, Seferovic P, Swedberg K, Tomkowski W, Achenbach S, Agewall S, Al-Attar N, Angel Ferrer J, Arad M, Asteggiano R, Bueno H, Caforio ALP, Carerj S, Ceconi C, Evangelista A, Flachskampf F, Giannakoulas G, Gielen S, Habib G, Kolh P, Lambrinou E, Lancellotti P, Lazaros G, Linhart A, Meurin P, Nieman K, Piepoli MF, Price S, Roos-Hesselink J, Roubille F, Ruschitzka F, Sagristà Sauleda J, Sousa-Uva M, Uwe Voigt J, Luis Zamorano J, Zamorano JL, Aboyans V, Achenbach S, Agewall S, Badimon L, Barón-Esquivias G, Baumgartner H, Bax JJ, Bueno H, Carerj S, Dean V, Erol Ç, Fitzimons D, Gaemperli O, Kirchhof P, Kolh P, Lancellotti P, Lip GY, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Roffi M, Torbicki A, Vaz Carneiro A, Windecker S, Shuka N, Sisakian H, Mascherbauer J, Isayev E, Shumavets V, Van Camp G, Gatzov P, Hanzevacki JS, Moustra HH, Linhart A, Møller JE, Aboleineen MW, Põder P, Lehtonen J, Antov S, Damy T, Schieffer B, Dimitriadis K, Kiss RG, Rafnsson A, Arad M, Novo S, Mirrakhimov E, Stradinš P, Kavoliuniene A, Codreanu A, Dingli P, Vataman E, El Hattaoui M, Samstad SO, Hoffman P, Lopes LR, Dimulescu DR, Arutyunov GP, Pavlovic M, Dúbrava J, Sauleda JS, Andersson B, Müller H, Bouma BJ, Abaci A, Archbold A, Nesukay E

Subjects
Pericardiocentesi, Prognosi, Myopericarditi, Tamponade, Constrictive pericarditi, Pericardial effusion, Pericarditi, Therapy, Aetiology, Guideline, Pericardium, Diagnosi
Abstract

Guidelines summarize and evaluate all available evidence on a particular issue at the time of the writing process, with the aim of assisting health professionals in selecting the best management strategies for an individual patient with a given condition, taking into account the impact on outcome, as well as the risk–benefit ratio of particular diagnostic or therapeutic means. Guidelines and recommendations should help health professionals to make decisions in their daily practice. However, the final decisions concerning an individual patient must be made by the responsible health professional(s) in consultation with the patient and caregiver as appropriate.

Published
2015

16. 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS

Author

Valgimigli, M, Bueno, H, Byrne, RA, Collet, JP, Costa, F, Jeppsson, A, Juni, P, Kastrati, A, Kolh, P, Mauri, L, Montalescot, G, Neumann, FJ, Petricevic, M, Roffi, M, Steg, PG, Windecker, S, Zamorano, JL, Levine, GN, Badimon, L, Vranckx, P, Agewall, S, Andreotti, F, Antman, E, Barbato, E, Bassand, JP, Bugiardini, R, Cikirikcioglu, M, Cuisset, T, De Bonis, M, Delgado, V, Fitzsimons, D, Oliver, G, Galie, N, Gilard, M, Hamm, CW, Ibanez, B, Iung, B, James, S, Knuuti, J, Landmesser, U, Leclercq, C, Lettino, M, Lip, G, Piepoli, MF, Pierard, L, Schwerzmann, M, Sechtem, U, Simpson, IA, Uva, MS, Stabile, E, Storey, RF, Tendera, M, Van De Werf, F, Verheugt, F, Aboyans, V, Task Force Dual Antiplatelet Ther, and European Asso Cardio-Thoracic Surg

Subjects
Ticagrelor, Stable angina, Aspirin, Stent thrombosis, Revascularization, Bleeding, Coronary artery bypass grafting, Guidelines, Acute coronary syndromes, Recommendation, Coronary artery disease, Clopidogrel, Percutaneous coronary intervention, Myocardial infarction, Non-cardiac surgery, Dual antiplatelet therapy, Stents, Stable coronary artery disease, Oral anticoagulant, DAPT score, Triple therapy, Prasugrel, Drug-eluting stents, Risk stratification, PRECISE-DAPT score
Published
2018

17. 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines The Task Force for cancer treatments and cardiovascular toxicity of the European Society of Cardiology (ESC)

Author

Zamorano, JL, Munoz, D, Aboyans, V, Asteggiano, R, Galderisi, M, Habib, G, Lenihan, DJ, Lip, GYH, Lyon, AR, Fernandez, TL, Mohty, D, Piepoli, MF, Tamargo, J, Torbicki, A, Suter, TM, Achenbach, S, Agewall, S, Badimon, L, Baron-Esquivias, G, Baumgartner, H, Bax, JJ, Bueno, H, Carerj, S, Dean, V, Gaemperli, O, Kirchhof, P, Kolh, P, Lancellotti, P, Nihoyannopoulos, P, Ponikowski, P, Roffi, M, Carneiro, AV, Windecker, S, Minotti, G, Cardinale, D, de Azambuja, E, Dent, S, Erol, C, Ewer, MS, Farmakis, D, Fietkau, R, Fitzsimons, D, McGale, P, and Ringwald, J

Subjects
cardio-oncology, myocardial dysfunction, cardiotoxicity, surveillance, cancer therapy, ischaemia, chemotherapy, early detection, arrhythmias, European Society of Cardiology
Published
2017

18. 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines: The Task Force for cancer treatments and cardiovascular toxicity of the European Society of Cardiology (ESC)

Author

Zamorano, JL, Lancellotti, P, Rodriguez Muñoz, D, Aboyans, V, Asteggiano, R, Galderisi, M, Habib, G, Lenihan, DJ, Lip, GY, Lyon, AR, Lopez Fernandez, T, Mohty, D, Piepoli, MF, Tamargo, J, Torbicki, A, Suter, TM, Achenbach, S, Agewall, S, Badimon, L, Barón-Esquivias, G, Baumgartner, H, Bax, JJ, Bueno, H, Carerj, S, Dean, V, Erol, Ç, Fitzsimons, D, Gaemperli, O, Kirchhof, P, Kolh, P, Nihoyannopoulos, P, Ponikowski, P, Roffi, M, Vaz Carneiro, A, Windecker, S, Authors/Task Force Members, ESC Committee for Practice Guidelines (CPG), University of Zurich, Zamorano, Jose Luis, Centre Hospitalier Universitaire de Liège (CHU-Liège), Neuroépidémiologie Tropicale (NET), CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST), Université de Limoges (UNILIM)-Université de Limoges (UNILIM), Università degli studi di Napoli Federico II, Unité de Recherche sur les Maladies Infectieuses Tropicales Emergentes (URMITE), Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes (URMITE), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, INSB-INSB-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, INSB-INSB-Centre National de la Recherche Scientifique (CNRS), British Heart Foundation, Action Against Cancer, Zamorano, Jose Lui, Lancellotti, Patrizio, Rodriguez Muñoz, Daniel, Aboyans, Victor, Asteggiano, Riccardo, Galderisi, Maurizio, Habib, Gilbert, Lenihan, Daniel J., Lip, Gregory Y. H., Lyon, Alexander R., Lopez Fernandez, Teresa, Mohty, Dania, Piepoli, Massimo F., Tamargo, Juan, Torbicki, Adam, Suter, Thomas M., Achenbach, Stephan, Agewall, Stefan, Badimon, Lina, Barón Esquivias, Gonzalo, Baumgartner, Helmut, Bax, Jeroen J., Bueno, Héctor, Carerj, Scipione, Dean, Veronica, Erol, Çetin, Fitzsimons, Donna, Gaemperli, Oliver, Kirchhof, Paulu, Kolh, Philippe, Nihoyannopoulos, Petro, Ponikowski, Piotr, Roffi, Marco, Vaz Carneiro, António, Windecker, Stephan, Lenihan, Daniel J, Lip, Gregory Y. H, Lyon, Alexander R, Piepoli, Massimo F, University of Naples Federico II = Università degli studi di Napoli Federico II, Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR48, and Institut des sciences biologiques (INSB-CNRS)-Institut des sciences biologiques (INSB-CNRS)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Vascular Endothelial Growth Factor A, Angiotensin receptor, Cardiac & Cardiovascular Systems, cardio-oncology, medicine.medical_treatment, myocardial dysfunction, 030204 cardiovascular system & hematology, ANTHRACYCLINE-INDUCED CARDIOMYOPATHY, chemotherapy, Coronary artery disease, 0302 clinical medicine, RENAL-CELL CARCINOMA, Authors/Task Force Members, Cancer Survivors, Neoplasms, Natriuretic peptide, 610 Medicine & health, early detection, ComputingMilieux_MISCELLANEOUS, Societies, Medical, HER2-POSITIVE BREAST-CANCER, TRASTUZUMAB-INDUCED CARDIOTOXICITY, Chemotherapy regimen, 3. Good health, Europe, medicine.anatomical_structure, 030220 oncology & carcinogenesis, CHEMOTHERAPY-INDUCED CARDIOTOXICITY, Practice Guidelines as Topic, cardiovascular system, Cardiology, surveillance, 10209 Clinic for Cardiology, cancer therapy, CORONARY-ARTERY-DISEASE, ESC Committee for Practice Guidelines (CPG), ischaemia, Immunotherapy, Cardiology and Cardiovascular Medicine, Life Sciences & Biomedicine, arrhythmias, Arrhythmia, Artery, Cardiovascular toxicity, medicine.medical_specialty, Heart Diseases, medicine.drug_class, Advisory Committees, Cancer therapy, Early detection, Antineoplastic Agents, [SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery, 1102 Cardiovascular Medicine And Haematology, 2705 Cardiology and Cardiovascular Medicine, European Society of Cardiology, 03 medical and health sciences, LEFT-VENTRICULAR DYSFUNCTION, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Internal medicine, medicine, TYROSINE KINASE INHIBITORS, Humans, cardiovascular diseases, Intensive care medicine, ACUTE LYMPHOBLASTIC-LEUKEMIA, Cardiotoxicity, Science & Technology, CONGESTIVE-HEART-FAILURE, Radiotherapy, business.industry, Arrhythmias, Cardio-oncology, Chemotherapy, Ischaemia, Myocardial dysfunction, Surveillance, Cancer, 10181 Clinic for Nuclear Medicine, Congresses as Topic, medicine.disease, Radiation therapy, Cardiovascular System & Hematology, Cardiovascular System & Cardiology, Position paper, business, human activities, Document Reviewers
Abstract

2-D : two-dimensional 3-D : three-dimensional 5-FU : 5-fluorouracil ACE : angiotensin-converting enzyme ARB : angiotensin II receptor blocker ASE : American Society of Echocardiography BNP : B-type natriuretic peptide CABG : coronary artery bypass graft CAD : coronary artery

Published
2016

19. ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD

Author

Rydén, L, Grant, Pj, Anker, Sd, Berne, C, Cosentino, F, Danchin, N, Deaton, C, Escaned, J, Hammes, Hp, Huikuri, H, Marre, M, Marx, N, Mellbin, L, Ostergren, J, Patrono, C, Seferovic, P, Uva, Ms, Taskinen, Mr, Tendera, M, Tuomilehto, J, Valensi, P, Zamorano, Jl, Achenbach, S, Baumgartner, H, Bax, Jj, Bueno, H, Dean, V, Erol, C, Fagard, R, Ferrari, R, Hasdai, D, Hoes, Aw, Kirchhof, P, Knuuti, J, Kolh, P, Lancellotti, P, Linhart, A, Nihoyannopoulos, P, Piepoli, Mf, Ponikowski, P, Sirnes, Pa, Tamargo, Jl, Torbicki, A, Wijns, W, Windecker, S, De Backer, G, Ezquerra, Ea, Avogaro, Angelo, Badimon, L, Baranova, E, Betteridge, J, Ceriello, A, Funck Brentano, C, Gulba, Dc, Kjekshus, Jk, Lev, E, Mueller, C, Neyses, L, Nilsson, Pm, Perk, J, Reiner, Z, Sattar, N, Schächinger, V, Scheen, A, Schirmer, H, Strömberg, A, Sudzhaeva, S, Viigimaa, M, Vlachopoulos, C, Xuereb, Rg, Authors/Task Force Members, ESC Committee for Practice Guidelines, and Document, Reviewers

Subjects
Male, Epidemiology, Smoking Prevention, Impaired glucose tolerance, Diabetes mellitus, Patient-Centered Care, Medicine, Child, Diagnostics, Smoking, Middle Aged, Cardiovascular disease, Prognosis, Patient management, Coronary Interventions, Cardiovascular Diseases, Pre diabetes, Child, Preschool, Female, Cardiology and Cardiovascular Medicine, Pharmacological treatment, Adult, medicine.medical_specialty, Adolescent, 610 Medicine & health, Guidelines, Prediabetic State, Young Adult, Internal medicine, Humans, Exercise, Aged, Glycated Hemoglobin, business.industry, Task force, Prevention, Settore MED/09 - MEDICINA INTERNA, Infant, medicine.disease, Diet, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Risk factors, business, Diabetic Angiopathies
Published
2013

20. 2014 ESC guidelines on the diagnosis and treatment of aortic diseases

Author

Erbel R, Aboyans, V, Boileau C, Bossone E, Di Bartolomeo R, Eggebrecht H, Evangelista A, Falk V, Frank H, Gaemperli O, Grabenwöger M, Haverich A, Iung B, Manolis AJ, Meijboom F, Nienaber CA, Roffi M, Rousseau H, Sechtem U, Sirnes PA, von Allmen RS, Vrints CJM, European Society of Cardiology (ESC), Zamorano JL, Achenbach S, Baumgartner H, Bax JJ, Bueno H, Dean V, Deaton C, Erol Ç, Fagard R, Ferrari R, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, Lancellotti P, Linhart A, Nihoyannopoulos P, Piepoli MF, Ponikowski P, Tamargo JL, Tendera M, Torbicki A, Wijns W, Windecker S., Erbel, R, Aboyans, V, Boileau, C, Bossone, E, Di Bartolomeo, R, Eggebrecht, H, Evangelista, A, Falk, V, Frank, H, Gaemperli, O, Grabenwöger, M, Haverich, A, Iung, B, Manolis, Aj, Meijboom, F, Nienaber, Ca, Roffi, M, Rousseau, H, Sechtem, U, Sirnes, Pa, von Allmen, R, Vrints, Cjm, European Society of Cardiology, (ESC), Zamorano, Jl, Achenbach, S, Baumgartner, H, Bax, Jj, Bueno, H, Dean, V, Deaton, C, Erol, Ç, Fagard, R, Ferrari, R, Hasdai, D, Hoes, A, Kirchhof, P, Knuuti, J, Kolh, P, Lancellotti, P, Linhart, A, Nihoyannopoulos, P, Piepoli, Mf, Ponikowski, P, Tamargo, Jl, Tendera, M, Torbicki, A, Wijns, W, and Windecker, S.

Published
2015

21. Metabolic exercise data combined with cardiac and kidney indexes: MECKI score. Predictive role in cardiopulmonary exercise testing with low respiratory exchange ratio in heart failure

Author

Corrà, U, Agostoni, P, Piepoli, Mf, Giordano, A, Mezzani, A, Giannuzzi, P, Cattadori, G, Fiorentini, C, Salvioni, E, Giovannardi, M, Veglia, F, Apostolo, A, Palermo, P, Contini, M, Vignati, C, Farina, S, Bovis, F, Cicoira, M, Vassanelli, C, La Gioia, R, Scrutinio, D, Passantino, A, Santoro, D, Campanale, S, Caputo, D, Scardovi, Ab, Ricci, R, Emdin, Michele, Metra, M, Dei Cas, L, Sinagra, G, Berton, E, Limongelli, G, Iorio, Am, Roselli, T, Buono, A, Calabrò, R, Raimondo, R, Vaninetti, R, Bertipaglia, D, Re, F, Guazzi, M, Belardinelli, R, Pietrucci, F, Parati, G, Magrì, D, Di Lenarda, A, Paolillo, S, Perrone Filardi, P, Passino, Claudio, Pastormerlo, Luigi Emilio, Malfatto, G, Caravita, S., Corrà, Ugo, Agostoni, Piergiuseppe, Piepoli, Massimo F., Giordano, Andrea, Mezzani, Alessandro, Giannuzzi, Pantaleo, Cattadori, Gaia, Fiorentini, Cesare, Salvioni, Elisabetta, Giovannardi, Marta, Veglia, Fabrizio, Apostolo, Anna, Palermo, Pietro, Contini, Mauro, Vignati, Carlo, Farina, Stefania, Bovis, Francesca, Cicoira, Mariantonietta, Vassanelli, Corrado, La Gioia, Rocco, Scrutinio, Domenico, Passantino, Andrea, Santoro, Daniela, Campanale, Saba, Caputo, Domenica, Scardovi, Angela B., Ricci, Roberto, Emdin, Michele, Metra, Marco, Dei Cas, Livio, Sinagra, Gianfranco, Berton, Emanuela, Limongelli, Giuseppe, Iorio, Anna Maria, Roselli, Teo, Buono, Andrea, Calabro', Raffaele, Raimondo, Rosa, Vaninetti, Raffaella, Bertipaglia, Donatella, Re, Federica, Guazzi, Marco, Belardinelli, Milano Romualdo, Pietrucci, Francesca, Parati, Gianfranco, Magrì, Damiano, Di Lenarda, Andrea, Paolillo, Stefania, Perrone Filardi, Pasquale, Passino, Claudio, Pastormerlo, Luigi E., Malfatto, Gabriella, Corrà, U, Agostoni, P, Piepoli, M, Giordano, A, Mezzani, A, Giannuzzi, P, Cattadori, G, Fiorentini, C, Salvioni, E, Giovannardi, M, Veglia, F, Apostolo, A, Palermo, P, Contini, M, Vignati, C, Farina, S, Bovis, F, Cicoira, M, Vassanelli, C, La Gioia, R, Scrutinio, D, Passantino, A, Santoro, D, Campanale, S, Caputo, D, Scardovi, A, Ricci, R, Emdin, M, Metra, M, Dei Cas, L, Sinagra, G, Berton, E, Limongelli, G, Iorio, A, Roselli, T, Buono, A, Calabrò, R, Raimondo, R, Vaninetti, R, Bertipaglia, D, Re, F, Guazzi, M, Belardinelli, M, Pietrucci, F, Parati, G, Magrì, D, Di Lenarda, A, Paolillo, S, Perrone Filardi, P, Passino, C, Pastormerlo, L, Malfatto, G, Calabrò, Raffaele, and DI LENARDA, Andrea

Subjects
Male, medicine.medical_specialty, Cardiopulmonary exercise, Heart failure, Oxygen consumption, Prognosis, Respiratory quotient, Prognosi, Renal function, Respiratory physiology, Kidney Function Tests, Severity of Illness Index, Predictive Value of Tests, Internal medicine, Severity of illness, medicine, Humans, Respiratory exchange ratio, Aged, Kidney, business.industry, Medicine (all), Middle Aged, medicine.disease, medicine.anatomical_structure, Predictive value of tests, Exercise Test, Respiratory Mechanics, Cardiology, Female, Energy Metabolism, Cardiology and Cardiovascular Medicine, business, cardiopulmonary exercise, heart failure, oxygen consumption, prognosis, respiratory quotient, aged, energy metabolism, exercise test, female, humans, kidney function tests, male, middle aged, predictive value of tests, respiratory mechanics, severity of illness index, cardiology and cardiovascular medicine
Abstract

n/a

Published
2015

22. Deceptive meaning of oxygen uptake measured at the anaerobic threshold in patients with systolic heart failure and atrial fibrillation

Author

Magrì D, Agostoni P, Corrà U, Passino C, Scrutinio D, Perrone Filardi P, Correale M, Cattadori G, Metra M, Girola D, Piepoli MF, Iorio A, Emdin M, Raimondo R, Re F, Cicoira M, Belardinelli R, Guazzi M, Clemenza F, Parati G, Frigerio M, Casenghi M, Scardovi AB, Ferraironi A, Di Lenarda A, Bussotti M, Apostolo A, Paolillo S, La Gioia R, Gargiulo P, Palermo P, Minà C, Farina S, Battaia E, Maruotti A, Pacileo G, Contini M, Oliva F, Ricci R, Sinagra G, on behalf of the Metabolic Exercise test data combined with Cardiac, Kidney Indexes Score Research Group, LIMONGELLI, Giuseppe, Magrì, D, Agostoni, P, Corrà, U, Passino, C, Scrutinio, D, Perrone Filardi, P, Correale, M, Cattadori, G, Metra, M, Girola, D, Piepoli, Mf, Iorio, A, Emdin, M, Raimondo, R, Re, F, Cicoira, M, Belardinelli, R, Guazzi, M, Limongelli, Giuseppe, Clemenza, F, Parati, G, Frigerio, M, Casenghi, M, Scardovi, Ab, Ferraironi, A, Di Lenarda, A, Bussotti, M, Apostolo, A, Paolillo, S, La Gioia, R, Gargiulo, P, Palermo, P, Minà, C, Farina, S, Battaia, E, Maruotti, A, Pacileo, G, Contini, M, Oliva, F, Ricci, R, Sinagra, G, on behalf of the Metabolic Exercise test data combined with, Cardiac, and Kidney Indexes Score Research, Group

Published
2014

23. 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines

Author

Zamorano, JL, Lancellotti, P, Munoz, DR, Aboyans, V, Asteggiano, R, Galderisi, M, Habib, G, Lenihan, DJ, Lyon, AR, Lopez Fernandez, T, Mohty, D, Tamargo, J, Suter, TM, Baron-Esquivias, G, Baumgartner, H, Bax, JJ, Dean, V, Kolh, P, Lip, GYH, Nihoyannopoulos, P, Piepoli, MF, Torbicki, A, Achenbach, S, Minotti, G, Agewall, S, Badimon, L, Bueno, H, Cardinale, D, Carerj, S, Curigliano, G, de Azambuja, E, Dent, S, Erol, C, Ewer, MS, Farmakis, D, Fietkau, R, Fitzsimons, D, Gaemperli, O, Kirchhof, P, Kohl, P, McGale, P, Ponikowski, P, Ringwald, J, Roffi, M, Schulz-Menger, J, Stebbing, J, Steiner, RK, Szmit, S, Carneiro, AV, and Windecker, S

Subjects
cardio-oncology, myocardial dysfunction, cardiotoxicity, surveillance, cancer therapy, ischaemia, chemotherapy, early detection, arrhythmias, European Society of Cardiology
Published
2016

24. 2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts): Developed with the special contribution of the European Association for Cardiovascular Prevention Rehabilitation (EACPR)

Author

Authors/Task Force Members, Piepoli MF, Hoes AW, Agewall S, Albus C, Brotons C, Catapano AL, Cooney MT, Corrà U, Cosyns B, Deaton C, Graham I, Hall MS, Hobbs FD, Løchen ML, Löllgen H, Marques-Vidal P, Perk J, Prescott E, Redon J, Richter DJ, Sattar N, Smulders Y, Tiberi M, van der Worp HB, van Dis I, Verschuren WM, Additional Contributor: Simone Binno (Italy), Document Reviewers, De Backer G, Roffi M, Aboyans V, Bachl N, Bueno H, Carerj S, Cho L, Cox J, De Sutter J, Egidi G, Fisher M, Fitzsimons D, Franco OH, Guenoun M, Jennings C, Jug B, Kirchhof P, Kotseva K, Lip GY, Mach F, Mancia G, Bermudo FM, Mezzani A, Niessner A, Ponikowski P, Rauch B, Rydén L, Stauder A, Turc G, Wiklund O, Windecker S, and Zamorano JL

Published
2016

25. 2016 European Guidelines on cardiovascular disease prevention in clinical practice

Author

Piepoli, MF, Hoes, AW, Agewall, S, Albus, C, Brotons, C, Catapano, AL, Cooney, MT, Corrà, U, Cosyns, B, Deaton, C, Graham, I, Hall, MS, Hobbs, FDR, Løchen, ML, Löllgen, H, Marques-Vidal, P, Perk, J, Prescott, E, Redon, J, Richter, DJ, Sattar, N, Smulders, Y, Tiberi, M, Van Der Worp, HB, Van Dis, I, Verschuren, WM M, Binno, S, De Backer, G, Roffi, M, Aboyans, V, Bachl, N, Carerj, S, Cho, Le, Cox, J, De Sutter, J, Egidi, G, Fisher, M, Fitzsimons, D, Franco, OH, Guenoun, M, Jennings, C, Jug, B, Kirchhof, P, Kotseva, K, Lip, GYH, Mach, F, Mancia, G, Bermudo, FM, Mezzani, A, Niessner, A, Ponikowski, P, Rauch, B, Stauder, A, Turc, G, Wiklund, O, Windecker, S, Zamorano, JL, Achenbach, S, Badimon, L, Barón-Esquivias, G, Baumgartner, H, Bax, JJ, Dean, V, Erol, Ç, Gaemperli, O, Kolh, P, Lancellotti, P, Nihoyannopoulos, P, Torbicki, A, Carneiro, AV, Metzler, B, Najafov, R, Stelmashok, V, De Maeyer, C, Dilić, M, Gruev, I, Miličić, D, Vaverkova, H, Gustafsson, I, Attia, I, Duishvili, D, Ferrières, J, Kostova, N, Klimiashvili, Z, Hambrecht, R, Tsioufis, K, Szabados, E, Andersen, K, Vaughan, C, Zafrir, B, Novo, S, Davletov, K, Jashari, F, Kerimkulova, A, Mintale, I, Saade, G, Petrulioniene, Z, Delagardelle, C, Magri, CJ, Rudi, V, Oukerraj, L, Çölkesen, BE, Schirmer, H, Dos Reis, RP, Gherasim, D, Nedogoda, S, Zavatta, M, Giga, V, Filipova, S, Padial, LR, Kiessling, A, Mahdhaoui, A, Ural, D, Nesukay, E, Gale, C, Piepoli, M, Hoes, A, Agewall, S, Albus, C, Brotons, C, Catapano, A, Cooney, M, Corrà, U, Cosyns, B, Deaton, C, Graham, I, Hall, M, Hobbs, F, Løchen, M, Löllgen, H, Marques-Vidal, P, Perk, J, Prescott, E, Redon, J, Richter, D, Sattar, N, Smulders, Y, Tiberi, M, Van Der Worp, H, Van Dis, I, Verschuren, W, Binno, S, De Backer, G, Roffi, M, Aboyans, V, Bachl, N, Carerj, S, Cho, L, Cox, J, De Sutter, J, Egidi, G, Fisher, M, Fitzsimons, D, Franco, O, Guenoun, M, Jennings, C, Jug, B, Kirchhof, P, Kotseva, K, Lip, G, Mach, F, Mancia, G, Bermudo, F, Mezzani, A, Niessner, A, Ponikowski, P, Rauch, B, Stauder, A, Turc, G, Wiklund, O, Windecker, S, Zamorano, J, Achenbach, S, Badimon, L, Barón-Esquivias, G, Baumgartner, H, Bax, J, Dean, V, Erol, Ç, Gaemperli, O, Kolh, P, Lancellotti, P, Nihoyannopoulos, P, Torbicki, A, Carneiro, A, Metzler, B, Najafov, R, Stelmashok, V, De Maeyer, C, Dilić, M, Gruev, I, Miličić, D, Vaverkova, H, Gustafsson, I, Attia, I, Duishvili, D, Ferrières, J, Kostova, N, Klimiashvili, Z, Hambrecht, R, Tsioufis, K, Szabados, E, Andersen, K, Vaughan, C, Zafrir, B, Novo, S, Davletov, K, Jashari, F, Kerimkulova, A, Mintale, I, Saade, G, Petrulioniene, Z, Delagardelle, C, Magri, C, Rudi, V, Oukerraj, L, Çölkesen, B, Schirmer, H, Dos Reis, R, Gherasim, D, Nedogoda, S, Zavatta, M, Giga, V, Filipova, S, Padial, L, Kiessling, A, Mahdhaoui, A, Ural, D, Nesukay, E, and Gale, C

Subjects
Adult, Diagnostic Imaging, Diabetic Angiopathie, Healthy Diet, General Practice, Population, Healthy lifestyle, Health Promotion, Sex Factor, Guideline, Guidelines, Diabete, Socioeconomic Factor, Blood pressure, Clinical settings, Diabetes, Lipid, Nutrition, Physical activity, Prevention, Primary care, Psychosocial factors, Rehabilitation, Risk assessment, Risk management, Smoking, Stakeholder, Cardiology and Cardiovascular Medicine, Cardiovascular Disease, Age Factor, Cost-Benefit Analysi, Practice Patterns, Physicians', Exercise, Aged, Cardiac Rehabilitation, Psychosocial factor, Biomarker, Middle Aged, Multiple Chronic Condition, Pedigree, Clinical setting, Antihypertensive Agent, Hyperlipidemia, Hypertension, Smoking Cessation, Human
Published
2016

26. Deceptive meaning of oxygen uptake measured at the anaerobic threshold in patients with systolic heart failure and atrial fibrillation

Author

Magrì D, Agostoni P, Corrà, U, Passino, C, Scrutinio, D, Perrone Filardi, P, Correale, M, Cattadori, G, Metra, M, Girola, D, Piepoli, Mf, Iorio, A, Emdin, M, Raimondo, R, Re, F, Cicoira, Mariantonietta, Belardinelli, R, Guazzi, M, Limongelli, G, Clemenza, F, Parati, G, Frigerio, M, Casenghi, M, Scardovi, Ab, Ferraironi, A, Di Lenarda, A, Bussotti, M, Apostolo, A, Paolillo, S, La Gioia, R, Gargiulo, P, Palermo, P, Minà, C, Farina, S, Battaia, E, Maruotti, A, Pacileo, G, Contini, M, Oliva, F, and Ricci, R.

Subjects
exercise capacity, heart failure, atrial fibrillation, exercise capacity, heart failure, atrial fibrillation
Published
2015

27. Guidelines on myocardial revascularization

Author

Task Force on Myocardial Revascularization of the European Society of Cardiology, the European Association for Cardio Thoracic Surgery, European Association for Percutaneous Cardiovascular Interventions, Wijns W, Kolh P, Danchin N, Di Mario C, Falk V, Folliguet T, Garg S, Huber K, James S, Knuuti J, Lopez Sendon J, Marco J, Menicanti L, Ostojic M, Piepoli MF, Pirlet C, Pomar JL, Reifart N, Ribichini FL, Schalij MJ, Sergeant P, Serruys PW, Silber S, Sousa Uva M, Taggart D. Collaborators: Vahanian A, Auricchio A, Bax J, Ceconi C, Dean V, Filippatos G, Funck Bretano C, Hobbs R, Kearney P, McDonagh T, Popescu BA, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Vardas PE, Widimsky P, Dunning J, Elia S, Kappetein P, Lockowandt U, Sarris G, Vouohe P, von Segesser L, Agewall S, Aladashvili A, Alexopoulos D, Antunes MJ, Atalar E, de la Riviere AB, Doganov A, Eha J, Fajadet J, Ferreira R, Garot J, Halcox J, Hasin Y, Janssens S, Kervinen K, Laufer G, Legrand V, Nashef SA, Neumann FJ, Niemela K, Nihoyannopoulos P, Noc M, Piek JJ, Pirk J, Rozenman Y, Sabate M, Starc R, Thielmann M, Wheatley DJ, Windecker S, Zembala M., ALFIERI , OTTAVIO, ACS - Amsterdam Cardiovascular Sciences, Cardiology, Task Force on Myocardial Revascularization of the European Society of, Cardiology, the European Association for Cardio Thoracic, Surgery, European Association for Percutaneous Cardiovascular, Intervention, Kolh, P, Wijns, W, Danchin, N, Di Mario, C, Falk, V, Folliguet, T, Garg, S, Huber, K, James, S, Knuuti, J, Lopez Sendon, J, Marco, J, Menicanti, L, Ostojic, M, Piepoli, Mf, Pirlet, C, Pomar, Jl, Reifart, N, Ribichini, Fl, Schalij, Mj, Sergeant, P, Serruys, Pw, Silber, S, Sousa Uva, M, Taggart D., Collaborators: Vahanian A, Auricchio, A, Bax, J, Ceconi, C, Dean, V, Filippatos, G, Funck Brentano, C, Hobbs, R, Kearney, P, Mcdonagh, T, Popescu, Ba, Reiner, Z, Sechtem, U, Sirnes, Pa, Tendera, M, Vardas, Pe, Widimsky, P, Alfieri, Ottavio, Dunning, J, Elia, S, Kappetein, P, Lockowandt, U, Sarris, G, Vouhe, P, von Segesser, L, Agewall, S, Aladashvili, A, Alexopoulos, D, Antunes, Mj, Atalar, E, de la Riviere, Ab, Doganov, A, Eha, J, Fajadet, J, Ferreira, R, Garot, J, Halcox, J, Hasin, Y, Janssens, S, Kervinen, K, Laufer, G, Legrand, V, Nashef, Sa, Neumann, Fj, Niemela, K, Nihoyannopoulos, P, Noc, M, Piek, Jj, Pirk, J, Rozenman, Y, Sabate, M, Starc, R, Thielmann, M, Wheatley, Dj, Windecker, S, Zembala, M., Funck Bretano, C, and Vouohe, P

Subjects
Carotid Artery Diseases, Graft Rejection, lcsh:Diseases of the circulatory (Cardiovascular) system, Judgement, Settore MED/21 - Chirurgia Toracica, Medizin, Heart Valve Diseases, Myocardial Ischemia, Contrast Media, Myocardial Revascularization, Assisted Circulation, General Environmental Science, Drug-Eluting Stents, General Medicine, Prognosis, Europe, Stroke, Acute Disease, Cardiology, Platelet aggregation inhibitor, Kidney Diseases, Medical emergency, Cardiology and Cardiovascular Medicine, Risk assessment, Pulmonary and Respiratory Medicine, Diagnostic Imaging, medicine.medical_specialty, Myocardial revascularization, MEDLINE, Renal Artery Obstruction, Risk Assessment, End stage renal disease, Blood Vessel Prosthesis Implantation, Fibrinolytic Agents, Patient Education as Topic, Internal medicine, Preoperative Care, medicine, Humans, Hypoglycemic Agents, Heart Failure, Postoperative Care, business.industry, Contraindications, Conflict of interest, Arrhythmias, Cardiac, Evidence-based medicine, medicine.disease, lcsh:RC666-701, Chronic Disease, General Earth and Planetary Sciences, Surgery, business, Fibrinolytic agent, Diabetic Angiopathies, Platelet Aggregation Inhibitors
Abstract

Guidelines and Expert Consensus Documents summarize and evaluate all available evidence with the aim of assisting physicians in selecting the best management strategy for an individual patient suffering from a given condition, taking into account the impact on outcome and the risk benefit ratio of diagnostic or therapeutic means. Guidelines are no substitutes for textbooks and their legal implications have been discussed previously. Guidelines and recommendations should help physicians to make decisions in their daily practice. However, the ultimate judgement regarding the care of an individual patient must be made by his/her responsible physician(s). The recommendations for formulating and issuing ESC Guidelines and Expert Consensus Documents can be found on the ESC website (http://www.escardio.org/knowledge/ guidelines/rules). Members of this Task Force were selected by the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) to represent all physicians involved with the medical and surgical care of patients with coronary artery disease (CAD). A critical evaluation of diagnostic and therapeutic procedures is performed including assessment of the risk benefit ratio. Estimates of expected health outcomes for society are included, where data exist. The level of evidence and the strength of recommendation of particular treatment options are weighed and graded according to predefined scales, as outlined in Tables 1 and 2. The members of the Task Force have provided disclosure statements of all relationships that might be perceived as real or potential sources of conflicts of interest. These disclosure forms are kept on file at European Heart House, headquarters of the ESC. Any changes in conflict of interest that arose during the writing period were notified to the ESC. The Task Force report received its entire financial support from the ESC and EACTS, without any involvement of the pharmaceutical, device, or surgical industry. ESC and EACTS Committees for Practice Guidelines are responsible for the endorsement process of these joint Guidelines. The finalized document has been approved by all the experts involved in the Task Force, and was submitted to outside specialists selected by both societies for review. The document is revised, and finally approved by ESC and EACTS and subsequently published simultaneously in the European Heart Journal and the European Journal of Cardio-Thoracic Surgery. After publication, dissemination of the Guidelines is of paramount importance. Pocket-sized versions and personal digital assistant-downloadable versions are useful at the point of care. Some surveys have shown that the intended users are sometimes unaware of the existence of guidelines, or simply do not translate them into practice. Thus, implementation programmes are needed because it has been shown that the outcome of disease may be favourably influenced by the thorough application of clinical recommendations.

Published
2010

28. Exercise intolerance in chronic heart failure: mechanisms and therapies. Part II

Author

Piepoli MF, Guazzi M, Cicoira M, Corrà U, Dalla Libera L, Emdin M, Mele D, Passino C, Vescovo G, Vigorito C, Villani G, Agostoni P., BORIANI, GIUSEPPE, Piepoli MF, Guazzi M, Boriani G, Cicoira M, Corrà U, Dalla Libera L, Emdin M, Mele D, Passino C, Vescovo G, Vigorito C, Villani G, and Agostoni P

Subjects
Heart Failure, Cachexia, Exercise Tolerance, Epidemiology, Multiple Organ Failure, Cardiovascular Agents, chronic heart failure, exercise testing, exercise tolerance, quality of life, rehabilitation, Cardiac Resynchronization Therapy, Dyspnea, Treatment Outcome, Chronic Disease, Muscle Fatigue, Reflex, Humans, Cardiology and Cardiovascular Medicine
Abstract

Muscular fatigue and dyspnoea on exertion are among the most common symptoms in chronic heart failure; however their origin is still poorly understood. Several studies have shown that cardiac dysfunction alone cannot fully explain their origin, but the contribution of the multiorgan failure present in this syndrome must be highlighted. We aimed to summarize the existing evidence and the most controversial aspects of the complex interplay of different factors involved in the symptom generation. In the first part of the review, six key factors were revised (the heart, the lung, the skeletal muscle, the hormonal changes, the O2 delivery to the periphery, the endothelium). In this second part, the role of the excitatory reflexes and the cardiac cachexia are presented. Finally, potential therapeutic implications are discussed here. We believe that a better knowledge of the pathophysiology of this syndrome may contribute to the management of the patients and to the improvement in their stress tolerance and quality of life.

Published
2010

29. Exercise intolerance in chronic heart failure: mechanisms and therapies

Author

Piepoli MF, Guazzi M, Boriani G, Cicoira M, Corrà U, Dalla Libera L, Emdin M, Mele D, Passino C, Vescovo G, Villani GQ, Agostoni P., VIGORITO, CARLO, Piepoli, Mf, Guazzi, M, Boriani, G, Cicoira, M, Corrà, U, Dalla Libera, L, Emdin, M, Mele, D, Passino, C, Vescovo, G, Vigorito, Carlo, Villani, G, Agostoni, P., and Villani, Gq

Subjects
cardiac rehabilitation, cronic heart failure, exercise intolerance, chronic heart failure
Abstract

Muscular fatigue and dyspnoea on exertion are among the most common symptoms in chronic heart failure; however their origin is still poorly understood. Several studies have shown that cardiac dysfunction alone cannot fully explain their origin, but the contribution of the multiorgan failure present in this syndrome must be highlighted. In this study, divided in two parts (see part II: pp. 643–648), we aimed to summarize the existing evidence and the most controversial aspects of the complex interplay of different factors involved in symptom generation. In this first part of the review, six key factors are revised: the heart, the lung, the skeletal muscle, the hormonal changes, the O2 delivery to the periphery, the endothelium. In the second part, the role of the excitatory reflexes and the cardiac cachexia will be presented, and finally, the potential therapeutic implications are discussed. We believe that a better knowledge of the pathophysiology of this syndrome may contribute to the management of the patients and to the improvement in their stress tolerance and quality of life.

Published
2010

30. 2014 ESC/EACTS Guidelines on myocardial revascularization

Author

Kolh, P, Alfonso, F, Collet, JP, Cremer, J, Falk, V, Filippatos, G, Hamm, C, Head, SJ, Juni, P, Kappetein, AP, Kastrati, A, Landmesser, U, Laufer, G, Neumann, FJ, Richter, DJ, Schauerte, P, Stefanini, GG, Taggart, DP, Torracca, L, Valgimigli, M, Witkowski, A, Baumgartner, H, Bax, JJ, Bueno, H, Dean, V, Erol, C, Fagard, R, Ferrari, R, Hoes, AW, Knuuti, J, Lancellotti, P, Linhart, A, Nihoyannopoulos, P, Piepoli, MF, Ponikowski, P, Sirnes, PA, Tamargo, JL, Tendera, M, Torbicki, A, Wijns, W, Windecker, S, Uva, MS, Achenbach, S, Pepper, J, Anyanwu, A, Badimon, L, Bauersachs, J, Baumbach, A, Beygui, F, Bonaros, N, De Carlo, M, Deaton, C, Dobrev, D, Dunning, J, Eeckhout, E, Gielen, S, Hasdai, D, Kirchhof, P, Luckraz, H, Mahrholdt, H, Montalescot, G, Paparella, D, Rastan, AJ, Sanmartin, M, Sergeant, P, Silber, S, Tamargo, J, ten Berg, J, Thiele, H, van Geuns, RJ, Wagner, HO, Wassmann, S, Wendler, O, and Zamorano, JL

Subjects
Stable angina, Medical therapy, Revascularization, Coronary artery bypass grafting, Acute coronary syndromes, Guidelines, Myocardial ischaemia, Recommendation, EuroSCORE, Coronary artery disease, Percutaneous coronary intervention, SYNTAX score, ST-segment elevation myocardial infarction, Myocardial infarction, Bare-metal stents, Myocardial revascularization, Heart Team, Stents, Stable coronary artery disease, Drug-eluting stents, Risk stratification
Published
2014

31. 2014 ESC/EACTS Guidelines on myocardial revascularization

Author

Windecker, S, Alfonso, F, Collet, JP, Cremer, J, Falk, V, Filippatos, G, Hamm, C, Head, SJ, Juni, P, Kappetein, AP, Kastrati, A, Landmesser, U, Laufer, G, Neumann, FJ, Richter, DJ, Schauerte, P, Uva, MS, Stefanini, GG, Taggart, DP, Torracca, L, Valgimigli, M, Wijns, W, Witkowski, A, Zamorano, JL, Achenbach, S, Baumgartner, H, Bax, JJ, Bueno, H, Dean, V, Deaton, C, Erol, C, Fagard, R, Ferrari, R, Hasdai, D, Hoes, AW, Kirchhof, P, Knuuti, J, Kolh, P, Lancellotti, P, Linhart, A, Nihoyannopoulos, N, Piepoli, MF, Ponikowski, P, Sirnes, PA, Tamargo, JL, Tendera, M, Torbicki, A, Pepper, J, Anyanwum, A, Badimon, L, Bauersachs, J, Baumbach, A, Beygui, F, Bonaros, N, De Carlo, M, Dobrev, D, Dunning, J, Eeckhout, E, Gielen, S, Luckraz, H, Mahrholdt, H, Montalescot, G, Paparella, D, Rastan, AJ, Sanmartin, M, Sergeant, P, Silber, S, Tamargo, J, ten Berg, J, Thiele, H, van Geuns, RJ, Wagner, HO, Wassmann, S, Wendler, O, Weidinger, F, Ibrahimov, F, Legrand, V, Terzic, I, Postadzhiyan, A, Skoric, B, Georgiou, GM, Zelizko, M, Junker, A, Eha, J, Romppanen, H, Bonnet, JL, Aladashvili, A, Hambrecht, R, Becker, D, Gudnason, T, Segev, A, Bugiardini, R, Sakhov, O, Mirrakhimov, A, Pereira, B, Felice, H, Trovik, T, Dudek, D, Pereira, H, Nedeljkovic, MA, Hudec, M, Cequier, A, Erlinge, D, Roffi, M, Kedev, S, Addad, F, Yildirir, A, and Davies, J

Subjects
Stable angina, Medical therapy, Revascularization, Coronary artery bypass grafting, Acute coronary syndromes, Guidelines, Myocardial ischaemia, Recommendation, EuroSCORE, Coronary artery disease, Percutaneous coronary intervention, SYNTAX score, ST-segment elevation myocardial infarction, Myocardial infarction, Bare-metal stents, Myocardial revascularization, Heart Team, Stents, Stable coronary artery disease, Drug-eluting stents, Risk stratification
Published
2014

32. ESC Guidelines on diabetes, pre- diabetes, and cardiovascular diseases developed in collaboration with the EASD - Summary

Author

Ryden, L, Grant, PJ, Anker, SD, Berne, C, Cosentino, F, Danchin, N, Escaned, J, Hammes, HP, Huikuri, H, Marre, M, Marx, N, Mellbin, L, Ostergren, J, Patrono, C, Seferovic, P, Sousa, M, Taskinen, MR, Tuomilehto, J, Valensi, P, Zamorano, JL, Achenbach, S, Bax, JJ, Bueno, H, Dean, V, Deaton, C, Erol, C, Ferrari, R, Kirchhof, P, Lancellotti, P, Linhart, A, Nihoyannopoulos, P, Piepoli, MF, Tendera, M, Torbicki, A, Wijns, W, Windecker, S, De Backer, G, Sirnes, PA, Ezquerra, EA, Avogaro, A, Badimon, L, Baranova, E, Baumgartner, H, Betteridge, J, Ceriello, A, Fagard, R, Funck-Brentano, C, Gulba, DC, Hasdai, D, Hoes, AW, Kjekshus, JK, Knuuti, J, Kolh, P, Lev, E, Mueller, C, Neyses, L, Nilsson, PM, Perk, J, Ponikowski, P, Reiner, Z, Sattar, N, Schachinger, V, Scheen, A, Schirmer, H, Stromberg, A, Sudzhaeva, S, Tamargo, JL, Viigimaa, M, Vlachopoulos, C, and Xuereb, RG

Subjects
impaired glucose tolerance, prevention, pharmacological treatment, cardiovascular disease, diabetes mellitus, diagnostics, risk factors, coronary interventions, epidemiology, prognosis, Guidelines, patient management
Published
2014

33. 2013 ESC guidelines on the management of stable coronary artery disease

Author

Sechtem, U, Achenbach, S, Andreotti, F, Budaj, A, Bugiardini, R, Crea, F, Cuisset, T, di Mario, C (Carlo), Ferreira, JR, Gersh, BJ, Gitt, AK, Hulot, JS, Marx, N, Opie, LH, Pfisterer, M, Prescott, E, Ruschitzka, F, Sabate, M, Senior, R, Taggart, DP, van der Wall, EE, Vrints, CJM, Knuuti, J, Valgimigli, M (Marco), Bueno, H, Claeys, MJ, Donner-Banzhoff, N, Erol, C, Frank, H, Funck-Brentano, C, Gaemperli, O, Gonzalez-Juanatey, JR, Hamilos, M, Hasdai, D, Husted, S, James, SK, Kervinen, K, Kolh, P, Kristensen, SD (Steen), Lancellotti, P, Maggioni, AP, Piepoli, MF, Pries, AR, Romeo, F, Ryden, L, Simoons, Maarten, Sirnes, PA, Steg, PG, Timmis, A, Wijns, W (William), Windecker, S, Yildirir, A, Zamorano, JL, and Cardiology

Abstract

ESC Committee for Practice Guidelines (CPG): Jose Luis Zamorano (Chairperson) (Spain), Stephan Achenbach (Germany), Helmut Baumgartner (Germany), Jeroen J. Bax (Netherlands), He ' ctor Bueno (Spain), Veronica Dean (France), Christi Deaton (UK), Cetin Erol (Turkey), Robert Fagard (Belgium), Roberto Ferrari (Italy), David Hasdai (Israel), ArnoW. Hoes (Netherlands), Paulus Kirchhof (Germany/UK), JuhaniKnuuti (Finland), PhilippeKolh (Belgium), Patrizio Lancellotti (Belgium), Ales Linhart (CzechRepublic), Petros Nihoyannopoulos (UK), Massimo F. Piepoli (Italy), Piotr Ponikowski (Poland), Per Anton Sirnes (Norway), Juan Luis Tamargo (Spain), Michal Tendera (Poland), AdamTorbicki (Poland), WilliamWijns (Belgium), StephanWindecker (Switzerland). Document Reviewers: Juhani Knuuti (CPG Review Coordinator) (Finland), Marco Valgimigli (Review Coordinator) (Italy), Hector Bueno (Spain), Marc J. Claeys (Belgium), Norbert Donner-Banzhoff (Germany), Cetin Erol (Turkey), Herbert Frank (Austria), Christian Funck-Brentano (France), Oliver Gaemperli (Switzerland), JoseR. Gonzalez-Juanatey (Spain), Michalis Hamilos (Greece), David Hasdai (Israel), Steen Husted (Denmark), Stefan K. James (Sweden), Kari Kervinen (Finland), Philippe Kolh (Belgium), Ste

Published
2013

34. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation

Author

Steg, Pg, James, Sk, Atar, D, Badano, Lp, Lundqvist, Cb, Borger, Ma, Di Mario, C, Dickstein, K, Ducrocq, G, Fernandez Aviles, F, Gershlick, Ah, Giannuzzi, P, Halvorsen, S, Huber, K, Juni, P, Kastrati, A, Knuuti, J, Lenzen, Mj, Mahaffey, Kw, Valgimigli, M, Van't Hof, A, Widimsky, P, Zahger, D, ESC Committee for Practice Guidelines, Bax, Jj, Baumgartner, H, Ceconi, Claudio, Dean, V, Deaton, C, Fagard, R, Funck Brentano, C, Hasdai, D, Hoes, A, Kirchhof, P, Kolh, P, Mcdonagh, T, Moulin, C, Popescu, Ba, Reiner, Z, Sechtem, U, Sirnes, Pa, Tendera, M, Torbicki, A, Vahanian, A, Windecker, S, Document, Reviewers, Astin, F, Aström Olsson, K, Budaj, A, Clemmensen, P, Collet, Jp, Fox, Ka, Fuat, A, Gustiene, O, Hamm, Cw, Kala, P, Lancellotti, P, Maggioni, Ap, Merkely, B, Neumann, Fj, Piepoli, Mf, Van de Werf, F, Verheugt, F, Wallentin, L., Steg, P, James, S, Atar, D, Badano, L, Lundqvist, C, Borger, M, Di Mario, C, Dickstein, K, Ducrocq, G, Fernandez-Aviles, F, Gershlick, A, Giannuzzi, P, Halvorsen, S, Huber, K, Juni, P, Kastrati, A, Knuuti, J, Lenzen, M, Mahaffey, K, Valgimigli, M, Van'T Hof, A, Widimsky, P, Zahger, D, Bax, J, Baumgartner, H, Ceconi, C, Dean, V, Deaton, C, Fagard, R, Funck-Brentano, C, Hasdai, D, Hoes, A, Kirchhof, P, Kolh, P, Mcdonagh, T, Moulin, C, Popescu, B, Reiner, Z, Sechtem, U, Sirnes, P, Tendera, M, Torbicki, A, Vahanian, A, Windecker, S, Astin, F, Astrom-Olsson, K, Budaj, A, Clemmensen, P, Collet, J, Fox, K, Fuat, A, Gustiene, O, Hamm, C, Kala, P, Lancellotti, P, Maggioni, A, Merkely, B, Neumann, F, Piepoli, M, Van De Werf, F, Verheugt, F, and Wallentin, L

Subjects
Emergency Medical Services, Biomedical Research, General Practice, Myocardial Infarction, Guideline, Anxiety, ST-segment elevation, Electrocardiography, Myocardial infarction, Coronary Artery Bypass, 610 Medicine & health, Fibrinolytic Agent, Cardiovascular diseases [NCEBP 14], Secondary prevention, General Medicine, Reperfusion therapy, Antifibrinolytic Agents, Exercise Therapy, Hospitalization, cardiovascular system, Cardiology, Acute coronary syndromes Ischaemic heart disease, Cardiomyopathies, Cardiology and Cardiovascular Medicine, Ticagrelor, Human, medicine.drug, Acute coronary syndrome, medicine.medical_specialty, Cardiotonic Agents, Pain, Myocardial Reperfusion, Acute myocardial infarction, Guidelines, Antifibrinolytic Agent, Risk Assessment, Time-to-Treatment, Percutaneous Coronary Intervention, Fibrinolytic Agents, Internal medicine, medicine, Humans, Cardiotonic Agent, Hemodynamic, cardiovascular diseases, Emergency Treatment, Cardiomyopathie, Heart Failure, Cardiac Imaging Technique, Management of acute coronary syndrome, Emergency Medical Service, business.industry, Coronary Artery Bypa, Platelet Aggregation Inhibitor, Hemodynamics, Arrhythmias, Cardiac, MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, medicine.disease, Long-Term Care, Primary percutaneous coronary intervention Antithrombotic therapy, Cardiac Imaging Techniques, Dyspnea, Hyperglycemia, Door-to-balloon, Myocardial infarction complications, Myocardial infarction diagnosis, business, Risk Reduction Behavior, Platelet Aggregation Inhibitors, Out-of-Hospital Cardiac Arrest, Forecasting
Abstract

ACE : angiotensin-converting enzyme ACS : acute coronary syndrome ADP : adenosine diphosphate AF : atrial fibrillation AMI : acute myocardial infarction AV : atrioventricular AIDA-4 : Abciximab Intracoronary vs. intravenously Drug Application APACHE II : Acute Physiology Aand Chronic

Published
2012

35. Guidelines on myocardial revascularization. T. F. on Myocardial Revascularization of the European Society of Cardiology (ESC),t. E. Association for Cardio-Thoracic Surgery (EACTS),E. A. for Percutaneous Cardiovascular Interventions

Author

Kolh, P, Wijns, W, Danchin, N, Di Mario, C, Falk, V, Folliguet, T, Garg, S, Huber, K, James, S, Knuuti, J, Lopez Sendon, J, Marco, J, Menicanti, L, Ostojic, M, Piepoli, Mf, Pirlet, C, Pomar, Jl, Reifart, N, Ribichini, Flavio Luciano, Schalij, Mj, Sergeant, P, Serruys, Pw, Silber, S, Sousa Uva, M, and Taggart, D.

Subjects
revascularization, myocardial, Guidelines
Published
2010

36. Exercise intolerance in chronic heart failure: mechanisms and therapies. Part II

Author

Piepoli, Mf, Guazzi, M, Boriani, G, Cicoira, Mariantonietta, Corrà, U, Dalla Libera, L, Emdin, M, Mele, D, Passino, C, Vescovo, G, Vigorito, C, Villani, G, Agostoni, P, Working Group 'Exercise Physiology, Sport Cardiology, and Cardiac Reahbilitation', Italian Society of Cardiology

Subjects
heart failure, exercise tolerance, rehabilitation
Published
2010

46. 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS

Author

Valgimigli, Marco, Bueno, Héctor, Byrne, Robert A, Collet, Jean-Philippe, Costa, Francesco, Jeppsson, Anders, Jüni, Peter, Kastrati, Adnan, Kolh, Philippe, Mauri, Laura, Montalescot, Gilles, Neumann, Franz-Josef, Petricevic, Mate, Roffi, Marco, Steg, Philippe Gabriel, Windecker, Stephan, Zamorano, Jose Luis, Levine, Glenn N, Badimon, Lina, Vranckx, Pascal, Agewall, Stefan, Andreotti, Felicita, Antman, Elliott, Barbato, Emanuele, Bassand, Jean-Pierre, Bugiardini, Raffaele, Cikirikcioglu, Mustafa, Cuisset, Thomas, De Bonis, Michele, Delgado, Victora, Fitzsimons, Donna, Gaemperli, Oliver, Galiè, Nazzareno, Gilard, Martine, Hamm, Christian W, Ibanez, Borja, Iung, Bernard, James, Stefan, Knuuti, Juhani, Landmesser, Ulf, Leclercq, Christophe, Lettino, Maddalena, Lip, Gregory, Piepoli, Massimo Francesco, Pierard, Luc, Schwerzmann, Markus, Sechtem, Udo, Simpson, Iain A, Uva, Miguel Sousa, Stabile, Eugenio, Storey, Robert F, Tendera, Michal, Van de Werf, Frans, Verheugt, Freek, Aboyans, Victor, Coca, Antonio, Collet, Jean- Philippe, Coman, Ioan Mircea, Dean, Veronica, Delgado, Victoria, Hindricks, Gerhard, Katus, Hugo A, Lancellotti, Patrizio, McDonagh, Theresa, Ponikowski, Piotr, Richter, Dimitrios J, Shlyakhto, Evgeny, Roithinger, Franz Xaver, Aliyev, Farid, Stelmashok, Valeriy, Desmet, Walter, Postadzhiyan, Arman, Georghiou, Georgios P, Motovska, Zuzana, Grove, Erik Lerkevang, Marandi, Toomas, Kiviniemi, Tuomas, Kedev, Sasko, Massberg, Steffen, Alexopoulos, Dimitrios, Kiss, Robert Gabor, Gudmundsdottir, Ingibjorg Jona, McFadden, Eugène P, Lev, Eli, De Luca, Leonardo, Sugraliyev, Akhmetzhan, Haliti, Edmond, Mirrakhimov, Erkin, Latkovskis, Gustavs, Petrauskiene, Birute, Huijnen, Steve, Magri, Caroline Jane, Cherradi, Rhizlan, Ten Berg, Jurrien M, Eritsland, Jan, Budaj, Andrzej, Aguiar, Carlos Tavares, Duplyakov, Dmitry, Zavatta, Marco, Antonijevic, Nebojsa M, Fras, Zlatko, Montoliu, Antonio Tello, Varenhorst, Christoph, Tsakiris, Dimitri, Addad, Faouzi, Aydogdu, Sinan, Parkhomenko, Alexander, Kinnaird, Tim, ESC Scientific Document Group, ESC Committee for Practice Guidelines (CPG), ESC National Cardiac Societies, Valgimigli, Marco, Bueno, Héctor, Byrne, Robert A., Collet, Jean-Philippe, Costa, Francesco, Jeppsson, Ander, Kastrati, Adnan, Kolh, Philippe, Mauri, Laura, Montalescot, Gille, Neumann, Franz-Josef, Petricevic, Mate, Roffi, Marco, Steg, Philippe Gabriel, Zamorano, Jose Lui, Levine, Glenn N., Badimon, Lina, Vranckx, Pascal, Agewall, Stefan, Andreotti, Felicita, Antman, Elliott, Barbato, Emanuele, Bassand, Jean-Pierre, Bugiardini, Raffaele, Cikirikcioglu, Mustafa, Cuisset, Thoma, De Bonis, Michele, Delgado, Victora, Fitzsimons, Donna, Galiè, Nazzareno, Gilard, Martine, Hamm, Christian W., Ibanez, Borja, James, Stefan, Knuuti, Juhani, Landmesser, Ulf, Leclercq, Christophe, Lettino, Maddalena, Lip, Gregory, Piepoli, Massimo Francesco, Pierard, Luc, Schwerzmann, Marku, Sechtem, Udo, Simpson, Iain A., Uva, Miguel Sousa, Stabile, Eugenio, Storey, Robert F., Tendera, Michal, Van De Werf, Fran, Verheugt, Freek, Aboyans, Victor, Windecker, Stephan, Coca, Antonio, Coman, Ioan Mircea, Dean, Veronica, Delgado, Victoria, Gaemperli, Oliver, Hindricks, Gerhard, Iung, Bernard, Jüni, Peter, Katus, Hugo A., Lancellotti, Patrizio, McDonagh, Theresa, Ponikowski, Piotr, Richter, DImitrios J., Shlyakhto, Evgeny, Roithinger, Franz Xaver, Aliyev, Farid, Stelmashok, Valeriy, Desmet, Walter, Postadzhiyan, Arman, Georghiou, Georgios P., Motovska, Zuzana, Grove, Erik Lerkevang, Marandi, Tooma, Kiviniemi, Tuoma, Kedev, Sasko, Massberg, Steffen, Alexopoulos, DImitrio, Kiss, Robert Gabor, Gudmundsdottir, Ingibjorg Jona, McFadden, Eugène P., Lev, Eli, De Luca, Leonardo, Sugraliyev, Akhmetzhan, Haliti, Edmond, Mirrakhimov, Erkin, Latkovskis, Gustav, Petrauskiene, Birute, Huijnen, Steve, Magri, Caroline Jane, Cherradi, Rhizlan, Ten Berg, Jurrien M., Eritsland, Jan, Budaj, Andrzej, Aguiar, Carlos Tavare, Duplyakov, Dmitry, Zavatta, Marco, Antonijevic, Nebojsa M., Fras, Zlatko, Montoliu, Antonio Tello, Varenhorst, Christoph, Tsakiris, DImitri, Addad, Faouzi, Aydogdu, Sinan, Parkhomenko, Alexander, Kinnaird, Tim, Valgimigli, M, Bueno, H, Byrne, Ra, Collet, Jp, Costa, F, Jeppsson, A, Juni, P, Kastrati, A, Kolh, P, Mauri, L, Montalescot, G, Neumann, Fj, Petricevic, M, Roffi, M, Steg, Pg, Windecker, S, Zamorano, Jl, Levine, Gn, Badimon, L, Vranckx, P, Agewall, S, Andreotti, F, Antman, E, Barbato, E, Bassand, Jp, Bugiardini, R, Cikirikcioglu, M, Cuisset, T, De Bonis, M, Delgado, V, Fitzsimons, D, Oliver, G, Galie, N, Gilard, M, Hamm, Cw, Ibanez, B, Iung, B, James, S, Knuuti, J, Landmesser, U, Leclercq, C, Lettino, M, Lip, G, Piepoli, Mf, Pierard, L, Schwerzmann, M, Sechtem, U, Simpson, Ia, Uva, M, Stabile, E, Storey, Rf, Tendera, M, Van De Werf, F, Verheugt, F, Aboyans, V, Byrne, Robert A, Levine, Glenn N, Badimon L, Vranckx P, Agewall S, Andreotti F, Antman E, Barbato E, Bassand JP, Bugiardini R, Cikirikcioglu M, Cuisset T, De Bonis M, Delgado V, Fitzsimons D, Gaemperli O, Galiè N, Gilard M, Hamm CW, Ibanez B, Iung B, James S, Knuuti J, Landmesser U, Leclercq C, Lettino M, Lip G, Piepoli MF, Pierard L, Schwerzmann M, Sechtem U, Simpson IA, Uva MS, Stabile E, Storey RF, Tendera M, Van de Werf F, Verheugt F, Aboyans V, Alma Mater Studiorum Universita' di Bologna, DIPARTIMENTO DI MEDICINA SPECIALISTICA, DIAGNOSTICA E SPERIMENTALE, DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE, Da definire, and AREA MIN. 06 - Scienze mediche

Subjects
Stable angina, Ticagrelor, Prasugrel, Stent thrombosi, Stent thrombosis, medicine.medical_treatment, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Coronary artery bypass grafting, 030204 cardiovascular system & hematology, Guideline, Coronary artery disease, Percutaneous coronary intervention, 0302 clinical medicine, Stent, DAPT score, 030212 general & internal medicine, Myocardial infarction, Drug-eluting stents, reproductive and urinary physiology, Societies, Medical, dual antiplatelet therapy, coronary artery disease, General Medicine, Clopidogrel, Europe, Cardiothoracic surgery, Non cardiac surgery, embryonic structures, Dual antiplatelet therapy, Cardiology, Stents, Stable coronary artery disease, Radiology, Acute coronary syndrome, biological phenomena, cell phenomena, and immunity, Cardiology and Cardiovascular Medicine, PRECISE-DAPT score, circulatory and respiratory physiology, medicine.drug, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Acute coronary syndromes, Guidelines, 03 medical and health sciences, Non-cardiac surgery, Internal medicine, medicine, Humans, cardiovascular diseases, Triple therapy, Risk stratification, Aspirin, business.industry, urogenital system, Revascularization, Bleeding, Oral anticoagulant, Recommendation, medicine.disease, Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, Surgery, Drug-eluting stent, business, Platelet Aggregation Inhibitors
Abstract

none 107 si Non presente mixed Valgimigli, Marco*; Bueno, Héctor; Byrne, Robert A.; Collet, Jean-Philippe; Costa, Francesco; Jeppsson, Anders; Kastrati, Adnan; Kolh, Philippe; Mauri, Laura; Montalescot, Gilles; Neumann, Franz-Josef; Petricevic, Mate; Roffi, Marco; Steg, Philippe Gabriel; Zamorano, Jose Luis; Levine, Glenn N.; Badimon, Lina; Vranckx, Pascal; Agewall, Stefan; Andreotti, Felicita; Antman, Elliott; Barbato, Emanuele; Bassand, Jean-Pierre; Bugiardini, Raffaele; Cikirikcioglu, Mustafa; Cuisset, Thomas; De Bonis, Michele; Delgado, Victora; Fitzsimons, Donna; Galiè, Nazzareno; Gilard, Martine; Hamm, Christian W.; Ibanez, Borja; James, Stefan; Knuuti, Juhani; Landmesser, Ulf; Leclercq, Christophe; Lettino, Maddalena; Lip, Gregory; Piepoli, Massimo Francesco; Pierard, Luc; Schwerzmann, Markus; Sechtem, Udo; Simpson, Iain A.; Uva, Miguel Sousa; Stabile, Eugenio; Storey, Robert F.; Tendera, Michal; Van De Werf, Frans; Verheugt, Freek; Aboyans, Victor; Windecker, Stephan; Coca, Antonio; Coman, Ioan Mircea; Dean, Veronica; Delgado, Victoria; Gaemperli, Oliver; Hindricks, Gerhard; Iung, Bernard; Jüni, Peter; Katus, Hugo A.; Lancellotti, Patrizio; McDonagh, Theresa; Ponikowski, Piotr; Richter, DImitrios J.; Shlyakhto, Evgeny; Roithinger, Franz Xaver; Aliyev, Farid; Stelmashok, Valeriy; Desmet, Walter; Postadzhiyan, Arman; Georghiou, Georgios P.; Motovska, Zuzana; Grove, Erik Lerkevang; Marandi, Toomas; Kiviniemi, Tuomas; Kedev, Sasko; Massberg, Steffen; Alexopoulos, DImitrios; Kiss, Robert Gabor; Gudmundsdottir, Ingibjorg Jona; McFadden, Eugène P.; Lev, Eli; De Luca, Leonardo; Sugraliyev, Akhmetzhan; Haliti, Edmond; Mirrakhimov, Erkin; Latkovskis, Gustavs; Petrauskiene, Birute; Huijnen, Steve; Magri, Caroline Jane; Cherradi, Rhizlan; Ten Berg, Jurrien M.; Eritsland, Jan; Budaj, Andrzej; Aguiar, Carlos Tavares; Duplyakov, Dmitry; Zavatta, Marco; Antonijevic, Nebojsa M.; Fras, Zlatko; Montoliu, Antonio Tello; Varenhorst, Christoph; Tsakiris, DImitri; Addad, Faouzi; Aydogdu, Sinan; Parkhomenko, Alexander; Kinnaird, Tim Valgimigli, Marco*; Bueno, Héctor; Byrne, Robert A.; Collet, Jean-Philippe; Costa, Francesco; Jeppsson, Anders; Kastrati, Adnan; Kolh, Philippe; Mauri, Laura; Montalescot, Gilles; Neumann, Franz-Josef; Petricevic, Mate; Roffi, Marco; Steg, Philippe Gabriel; Zamorano, Jose Luis; Levine, Glenn N.; Badimon, Lina; Vranckx, Pascal; Agewall, Stefan; Andreotti, Felicita; Antman, Elliott; Barbato, Emanuele; Bassand, Jean-Pierre; Bugiardini, Raffaele; Cikirikcioglu, Mustafa; Cuisset, Thomas; De Bonis, Michele; Delgado, Victora; Fitzsimons, Donna; Galiè, Nazzareno; Gilard, Martine; Hamm, Christian W.; Ibanez, Borja; James, Stefan; Knuuti, Juhani; Landmesser, Ulf; Leclercq, Christophe; Lettino, Maddalena; Lip, Gregory; Piepoli, Massimo Francesco; Pierard, Luc; Schwerzmann, Markus; Sechtem, Udo; Simpson, Iain A.; Uva, Miguel Sousa; Stabile, Eugenio; Storey, Robert F.; Tendera, Michal; Van De Werf, Frans; Verheugt, Freek; Aboyans, Victor; Windecker, Stephan; Coca, Antonio; Coman, Ioan Mircea; Dean, Veronica; Delgado, Victoria; Gaemperli, Oliver; Hindricks, Gerhard; Iung, Bernard; Jüni, Peter; Katus, Hugo A.; Lancellotti, Patrizio; McDonagh, Theresa; Ponikowski, Piotr; Richter, DImitrios J.; Shlyakhto, Evgeny; Roithinger, Franz Xaver; Aliyev, Farid; Stelmashok, Valeriy; Desmet, Walter; Postadzhiyan, Arman; Georghiou, Georgios P.; Motovska, Zuzana; Grove, Erik Lerkevang; Marandi, Toomas; Kiviniemi, Tuomas; Kedev, Sasko; Massberg, Steffen; Alexopoulos, DImitrios; Kiss, Robert Gabor; Gudmundsdottir, Ingibjorg Jona; McFadden, Eugène P.; Lev, Eli; De Luca, Leonardo; Sugraliyev, Akhmetzhan; Haliti, Edmond; Mirrakhimov, Erkin; Latkovskis, Gustavs; Petrauskiene, Birute; Huijnen, Steve; Magri, Caroline Jane; Cherradi, Rhizlan; Ten Berg, Jurrien M.; Eritsland, Jan; Budaj, Andrzej; Aguiar, Carlos Tavares; Duplyakov, Dmitry; Zavatta, Marco; Antonijevic, Nebojsa M.; Fras, Zlatko; Montoliu, Antonio Tello; Varenhorst, Christoph; Tsakiris, DImitri; Addad, Faouzi; Aydogdu, Sinan; Parkhomenko, Alexander; Kinnaird, Tim

Published
2018

47. Delphi consensus recommendations on how to provide cardiovascular rehabilitation in the COVID-19 era

Author

Thomas Berger, Evangelia Kouidi, Ana Abreu, C H Davos, Marie Christine Iliou, Wolfram Doehner, Véronique Cornelissen, Carlo Vigorito, Alain Cohen-Solal, Heinz Völler, Josef Niebauer, Maria Simonenko, Marco Ambrosetti, Elio Venturini, Dominique Hansen, Dan Gaita, Carlos Peña Gil, Hareld M. C. Kemps, Bernhard H. Rauch, Paul Dendale, Nicolle Kraenkel, Chiara Giuseppina Beccaluva, Roberto F E Pedretti, Daniel Neunhaeuserer, Mathias Wilhelm, Marinella Sommaruga, Miguel Mendes, Massimo F Piepoli, Andreas B. Gevaert, Jari A. Laukkanen, Paul Beckers, Ines Frederix, Bruno Pavy, Simona Sarzi Braga, Antonio Mazza, Francesco Maranta, Repositório da Universidade de Lisboa, Ambrosetti, M, Abreu, A, Cornelissen, V, HANSEN, Dominique, Iliou, MC, Kemps, H, Pedretti, RFE, Voller, H, Wilhelm, M, Piepoli, MF, Beccaluva, CG, Beckers, P, Berger, T, Davos, CH, DENDALE, Paul, Doehner, W, FREDERIX, Ines, Gaita, D, Gevaert, A, Kouidi, E, Kraenkel, N, Laukkanen, J, Maranta, F, Mazza, A, Mendes, M, Neunhaeuserer, D, Niebauer, J, Pavy, B, Gil, CP, Rauch, B, Braga, SS, Simonenko, M, Cohen-Solal, A, Sommaruga, M, Venturini, E, Vigorito, C, Future Everyday, and Eindhoven MedTech Innovation Center

Subjects
medicine.medical_specialty, Consensus, Referral, Coronavirus disease 2019 (COVID-19), Delphi Technique, Epidemiology, medicine.medical_treatment, Comorbidity, 030204 cardiovascular system & hematology, SDG 3 – Goede gezondheid en welzijn, Likert scale, 03 medical and health sciences, 0302 clinical medicine, SDG 3 - Good Health and Well-being, COVID-19, Cardiovascular disease, Coronavirus, Prevention, Rehabilitation, Intervention (counseling), medicine, Humans, 030212 general & internal medicine, 610 Medicine & health, Consensus Document, Pandemics, computer.programming_language, COVID-19/epidemiology, Cardiac Rehabilitation, business.industry, SARS-CoV-2, Cardiovascular Diseases/epidemiology, medicine.disease, Cardiovascular Diseases, Family medicine, Human medicine, Cardiology and Cardiovascular Medicine, business, computer, Delphi, Cardiac Rehabilitation/methods, Cardiovascular rehabilitation
Abstract

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2020. For permissions, please email: journals.permissions@oup.com., This Delphi consensus by 28 experts from the European Association of Preventive Cardiology (EAPC) provides initial recommendations on how cardiovascular rehabilitation (CR) facilities should modulate their activities in view of the ongoing coronavirus disease 2019 (COVID-19) pandemic. A total number of 150 statements were selected and graded by Likert scale [from -5 (strongly disagree) to +5 (strongly agree)], starting from six open-ended questions on (i) referral criteria, (ii) optimal timing and setting, (iii) core components, (iv) structure-based metrics, (v) process-based metrics, and (vi) quality indicators. Consensus was reached on 58 (39%) statements, 48 'for' and 10 'against' respectively, mainly in the field of referral, core components, and structure of CR activities, in a comprehensive way suitable for managing cardiac COVID-19 patients. Panelists oriented consensus towards maintaining usual activities on traditional patient groups referred to CR, without significant downgrading of intervention in case of COVID-19 as a comorbidity. Moreover, it has been suggested to consider COVID-19 patients as a referral group to CR per se when the viral disease is complicated by acute cardiovascular (CV) events; in these patients, the potential development of COVID-related CV sequelae, as well as of pulmonary arterial hypertension, needs to be focused. This framework might be used to orient organization and operational of CR programmes during the COVID-19 crisis.

Published
2020

48. Severe heart failure prognosis evaluation for transplant selection in the era of beta-blockers: Role of peak oxygen consumption

Author

Marco Metra, Angela Beatrice Scardovi, Marco Guazzi, Giuseppe Pacileo, Rocco La Gioia, Romualdo Belardinelli, Annamaria Iorio, Alessandro Mezzani, Cesare Fiorentini, Claudio Passino, Anna Apostolo, Massimo F Piepoli, Elisabetta Salvioni, Gaia Cattadori, Ugo Corrà, Gianfranco Sinagra, Pantaleo Giannuzzi, Pietro Palermo, Mauro Contini, Andrea Di Lenarda, Domenico Scrutinio, Stefania Paolillo, Gianfranco Parati, Piergiuseppe Agostoni, Giuseppe Limongelli, Federica Re, Elisa Battaia, Fabrizio Veglia, Michele Emdin, Rosa Raimondo, Mariantonietta Cicoira, Damiano Magrì, Cattadori, G, Agostoni, P, Corrà, U, DI LENARDA, Andrea, Sinagra, Gianfranco, Veglia, F, Salvioni, E, La Gioia, R, Scardovi, Ab, Emdin, M, Metra, M, Limongelli, G, Raimondo, R, Re, F, Guazzi, M, Belardinelli, R, Parati, G, Magrì, D, Fiorentini, C, Mezzani, A, Scrutinio, D, Pacileo, G, Apostolo, A, Iorio, A, Paolillo, S, Palermo, P, Contini, M, Giannuzzi, P, Battaia, E, Cicoira, M, Passino, C, Piepoli, Mf, MECKI score research, Group, Cattadori, G., Agostoni, P., Corra, U., Di Lenarda, A., Sinagra, G., Veglia, F., Salvioni, E., La Gioia, R., Scardovi, A. B., Emdin, M., Metra, M., Limongelli, G., Raimondo, R., Re, F., Guazzi, M., Belardinelli, R., Parati, G., Magri, D., Fiorentini, C., Mezzani, A., Scrutinio, D., Pacileo, G., Apostolo, A., Iorio, A., Paolillo, S., Palermo, P., Contini, M., Giannuzzi, P., Battaia, E., Cicoira, M., Passino, C., Piepoli, M. F., Di Lenarda, A, Sinagra, G, Scardovi, A, and Piepoli, M

Subjects
Male, medicine.medical_treatment, chronic, heart, failure, Severity of Illness Index, Beta-blockers, Aortic valve replacement, Heart transplantation, Ejection fraction, exercise, Middle Aged, Prognosis, failure, chronic, Survival Rate, Exercise, Heart failure, Oxygen consumption, Adrenergic beta-Antagonists, Aged, Female, Follow-Up Studies, Heart Failure, Heart Transplantation, Humans, Oxygen Consumption, Patient Selection, cardiovascular system, Cardiology, Cardiology and Cardiovascular Medicine, Human, medicine.medical_specialty, Prognosi, heart, Follow-Up Studie, Internal medicine, Severity of illness, medicine, Beta-blocker, Intensive care medicine, Beta (finance), Survival rate, business.industry, Exercise, Oxygen consumption, Beta-blockers, Heart failure, Prognosis, Adrenergic beta-Antagonist, beta-blockers, heart failure, oxygen consumption, prognosis, MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, medicine.disease, Stenosis, business
Abstract

fraction. Rev Esp Cardiol 2013;66:261–8. [9] Herrmann HC, Pibarot P, Hueter I, et al. Predictors of mortality and outcomes of therapy in low-flow severe aortic stenosis: a Placement of Aortic Transcatheter Valves (PARTNER) Trial analysis. Circulation 2013;127:2316–26. [10] Ozkan A, Hachamovitch R, Kapadia SR, Tuzcu EM,Marwick TH. Impact of aortic valve replacement on outcome of symptomatic patients with severe aortic stenosis with low gradient and preserved left ventricular ejection fraction. Circulation 2013;128(6):622–31.

Published
2013

50. Exercise intolerance in chronic heart failure: mechanisms and therapies. Part I

Author

Donato Mele, Mariantonietta Cicoira, Marco Guazzi, Carlo Vigorito, Giovanni Quinto Villani, Ugo Corrà, Piergiuseppe Agostoni, Luciano Dalla Libera, Michele Emdin, Giorgio Vescovo, Massimo F. Piepoli, Giuseppe Boriani, Claudio Passino, Piepoli MF, Guazzi M, Boriani G, Cicoira M, Corrà U, Dalla Libera L, Emdin M, Mele D, Passino C, Vescovo G, Vigorito C, Villani GQ, and Agostoni P.

Subjects
medicine.medical_specialty, Epidemiology, Multiple Organ Failure, Exercise intolerance, rehabilitation, chronic heart failure, exercise testing, exercise tolerance, quality of life, Physical medicine and rehabilitation, Quality of life, medicine, Humans, Exertion, Intensive care medicine, Lung, Heart Failure, Exercise Tolerance, Muscle fatigue, business.industry, Heart, Cardiac cachexia, medicine.disease, Hormones, Pathophysiology, Oxygen, Dyspnea, Treatment Outcome, medicine.anatomical_structure, Heart failure, Chronic Disease, Muscle Fatigue, Endothelium, Vascular, medicine.symptom, Cardiology and Cardiovascular Medicine, business
Abstract

Muscular fatigue and dyspnoea on exertion are among the most common symptoms in chronic heart failure; however their origin is still poorly understood. Several studies have shown that cardiac dysfunction alone cannot fully explain their origin, but the contribution of the multiorgan failure present in this syndrome must be highlighted. In this study, divided in two parts (see part II: pp. 643–648), we aimed to summarize the existing evidence and the most controversial aspects of the complex interplay of different factors involved in symptom generation. In this first part of the review, six key factors are revised: the heart, the lung, the skeletal muscle, the hormonal changes, the O2 delivery to the periphery, the endothelium. In the second part, the role of the excitatory reflexes and the cardiac cachexia will be presented, and finally, the potential therapeutic implications are discussed. We believe that a better knowledge of the pathophysiology of this syndrome may contribute to the management of the patients and to the improvement in their stress tolerance and quality of life.

Published
2010

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