Search

Your search keyword '"Picht, Thomas"' showing total 584 results
Start Over Author "Picht, Thomas"
584 results on '"Picht, Thomas"'

9. Clinical diagnostic utility of transcranial magnetic stimulation in neurological disorders. Updated report of an IFCN committee

Author

Vucic, Steve, Stanley Chen, Kai-Hsiang, Kiernan, Matthew C., Hallett, Mark, Benninger, David.H., Di Lazzaro, Vincenzo, Rossini, Paolo M, Benussi, Alberto, Berardelli, Alfredo, Currà, Antonio, Krieg, Sandro M, Lefaucheur, Jean-Pascal, Long Lo, Yew, Macdonell, Richard A, Massimini, Marcello, Rosanova, Mario, Picht, Thomas, Stinear, Cathy M, Paulus, Walter, Ugawa, Yoshikazu, Ziemann, Ulf, and Chen, Robert

Published
2023
Full Text
View/download PDF

12. Preoperative subjective impairments in language and memory in brain tumor patients.

Author

Rybka, Lena, Jonkers, Roel, Burzlaff, Milena, Rosenstock, Tizian, Vajkoczy, Peter, Picht, Thomas, Faust, Katharina, and Rofes, Adrià

Subjects
MEMORY disorders, BRAIN tumors, TUMOR grading, SEMI-structured interviews, QUALITY of life
Abstract

Background: Subjective reports can reveal relevant information regarding the nature of the impairment of brain tumor patients, unveiling potential gaps in current assessment practices. The co-occurrence of language and memory impairments has been previously reported, albeit scarcely. The aim of this study is therefore to understand the co-occurrence of subjective language and memory complaints in the preoperative state of brain tumor patients and its impact on Quality of Life (QoL). Methods: 31 brain tumor patients (12 LGG, 19 HGG) underwent a semi-structured interview to assess subjective complaints of language deficits, co-occurrences between language and memory dysfunction, and changes in QoL. Group and subgroup analyses were conducted to provide general and tumor grade specific data. Results: 48.4% of patients mentioned co-occurrence of language and memory impairments in reading, writing, and conversation. The HGG group reported co-occurrences in all three of these (reading: 31.6%; writing: 21.1%; conversation: 26.3%), while the LGG only described co-occurrences in reading (25%) and conversation (8.3%), although these were not statistically significant. All patients with co-occurring language and memory deficits reported these to be linked to reduced QoL (48.4%). In patients with an HGG, this number was slightly higher (52.6%) than in patients with an LGG (41.7%). Conclusion: Language impairments co-occur with memory dysfunction as perceived in patients' daily life. Patients see these impairments as affecting their quality of life. Further attention to dedicated language and memory tasks seems necessary. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

24. VR Simulation of Novel Hands-Free Interaction Concepts for Surgical Robotic Visualization Systems

Author

You, Fang, Khakhar, Rutvik, Picht, Thomas, Dobbelstein, David, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Martel, Anne L., editor, Abolmaesumi, Purang, editor, Stoyanov, Danail, editor, Mateus, Diana, editor, Zuluaga, Maria A., editor, Zhou, S. Kevin, editor, Racoceanu, Daniel, editor, and Joskowicz, Leo, editor

Published
2020
Full Text
View/download PDF

25. The digital twin in neuroscience: from theory to tailored therapy.

Author

Fekonja, Lucius Samo, Schenk, Robert, Schröder, Emily, Tomasello, Rosario, Tomšič, Samo, and Picht, Thomas

Subjects
DIGITAL twins, LARGE-scale brain networks, BRAIN tumors, BRAIN diseases, PHYSICAL mobility
Abstract

Digital twins enable simulation, comprehensive analysis and predictions, as virtual representations of physical systems. They are also finding increasing interest and application in the healthcare sector, with a particular focus on digital twins of the brain. We discuss how digital twins in neuroscience enable the modeling of brain functions and pathology as they offer an in-silico approach to studying the brain and illustrating the complex relationships between brain network dynamics and related functions. To showcase the capabilities of digital twinning in neuroscience we demonstrate how the impact of brain tumors on the brain's physical structures and functioning can be modeled in relation to the philosophical concept of plasticity. Against this technically derived backdrop, which assumes that the brain's nonlinear behavior toward improvement and repair can be modeled and predicted based on MRI data, we further explore the philosophical insights of Catherine Malabou. Malabou emphasizes the brain's dual capacity for adaptive and destructive plasticity. We will discuss in how far Malabou's ideas provide a more holistic theoretical framework for understanding how digital twins can model the brain's response to injury and pathology, embracing Malabou's concept of both adaptive and destructive plasticity which provides a framework to address such yet incomputable aspects of neuroscience and the sometimes seemingly unfavorable dynamics of neuroplasticity helping to bridge the gap between theoretical research and clinical practice. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

28. Analysis of bihemispheric language function in pediatric neurosurgical patients using repetitive navigated transcranial magnetic stimulation

Author

Rosenstock, Tizian, primary, Schneider, Heike, additional, Neymeyer, Mitra Lara, additional, Becker, Lena-Luise, additional, Schulz, Bettina, additional, Tietze, Anna, additional, Hernáiz Driever, Pablo, additional, Kaindl, Angela M., additional, Vajkoczy, Peter, additional, Picht, Thomas, additional, and Thomale, Ulrich-Wilhelm, additional

Published
2024
Full Text
View/download PDF

31. Resection of Motor Eloquent Metastases Aided by Preoperative nTMS-Based Motor Maps—Comparison of Two Observational Cohorts

Author

Krieg, Sandro M, Picht, Thomas, Sollmann, Nico, Bährend, Ina, Ringel, Florian, Nagarajan, Srikantan S, Meyer, Bernhard, and Tarapore, Phiroz E

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Trials and Supportive Activities, Clinical Research, Cancer, Brain Disorders, 6.4 Surgery, Evaluation of treatments and therapeutic interventions, brain metastases, matched pair, preoperative mapping, Rolandic region, transcranial magnetic stimulation, Oncology and Carcinogenesis, Clinical sciences, Oncology and carcinogenesis
Abstract

IntroductionPreoperative mapping of motor areas with navigated transcranial magnetic stimulation (nTMS) has been shown to improve surgical outcomes for peri-Rolandic lesions and, in particular, for gliomas. However, the impact of this technique on surgical outcomes for peri-Rolandic metastatic lesions is yet unknown.ObjectiveTo investigate the impact of nTMS on surgical outcomes for peri-Rolandic metastatic lesions, various clinical parameters were analyzed in our international study group.MethodsTwo prospectively enrolled cohorts were compared by investigating patients receiving preoperative nTMS (2010-2015; 120 patients) and patients who did not receive preoperative nTMS (2006-2015; 130 patients). Tumor location, pathology, size, and preoperative deficits were comparable.ResultsThe nTMS group showed a lower rate of residual tumor on postoperative magnetic resonance imaging (odds ratio 0.3025; 95% confidence interval 0.1356-0.6749). On long-term follow-up, surgery-related paresis was decreased in the nTMS group (nTMS vs. non-nTMS; improved: 30.8 vs. 13.1%, unchanged: 65.8 vs. 73.8%, worse: 3.4 vs. 13.1% of patients; p = 0.0002). Moreover, the nTMS group received smaller craniotomies (nTMS: 16.7 ± 8.6 cm2 vs. non-nTMS: 25.0 ± 17.1 cm2; p

Published
2016

32. Low-frequency repetitive transcranial magnetic stimulation in patients with motor deficits after brain tumor resection: a randomized, double-blind, sham-controlled trial

Author

Engelhardt, Melina, Schneider, Heike, Reuther, Jan, Grittner, Ulrike, Vajkoczy, Peter, Picht, Thomas, Rosenstock, Tizian, Engelhardt, Melina, Schneider, Heike, Reuther, Jan, Grittner, Ulrike, Vajkoczy, Peter, Picht, Thomas, and Rosenstock, Tizian

Abstract

Objective: Surgical resection of motor eloquent tumors poses the risk of causing postoperative motor deficits which leads to reduced quality of life in these patients. Currently, rehabilitative procedures are limited with physical therapy being the main treatment option. This study investigated the efficacy of repetitive navigated transcranial magnetic stimulation (rTMS) for treatment of motor deficits after supratentorial tumor resection. Methods: This randomized, double-blind, sham-controlled trial (DRKS00010043) recruited patients with a postoperatively worsened upper extremity motor function immediately postoperatively. They were randomly assigned to receive rTMS (1Hz, 110% RMT, 15 minutes, 7 days) or sham stimulation to the motor cortex contralateral to the injury followed by physical therapy. Motor and neurological function as well as quality of life were assessed directly after the intervention, one month and three months postoperatively. Results: Thirty patients were recruited for this study. There was no significant difference between both groups in the primary outcome, the Fugl Meyer score three months postoperatively [Group difference (95%-CI): 5.05 (-16.0; 26.1); p=0.631]. Patients in the rTMS group presented with better hand motor function one month postoperatively. Additionally, a subgroup of patients with motor eloquent ischemia showed lower NIHSS scores at all timepoints. Conclusions: Low-frequency rTMS facilitated the recovery process in stimulated hand muscles, but with limited generalization to other functional deficits. Long-term motor deficits were not impacted by rTMS. Given the reduced life expectancy in these patients a shortened recovery duration of deficits can still be of high significance. Clinical Trial Registration: https://drks.de/DRKS00010043., Peer Reviewed

Published
2024

36. Non-cadaveric spine surgery simulator training in neurosurgical residency

Author

Pöser, Paul, Schenk, Robert, Miller, Hannah, Alghamdi, Ahmad, Lavalley, Adrien, Tielking, Katharina, Nissimov, Nitzan, Früh, Anton, Chakkalakal, Denny, Patsouris, Victor, Sargut, Tarik Alp, Mertens, Robert, Xu, Ran, Truckenmüller, Peter, Ferdowssian, Kiarash, Rösler, Judith, Wasilewski, David, Jelgersma, Claudius, Roethe, Anna, Sanchin, Aminaa, Vajkoczy, Peter, Picht, Thomas, and Onken, Julia Sophie

Published
2024
Full Text
View/download PDF

38. White Matter Tract Density Index Prediction Model of Overall Survival in Glioblastoma

Author

Salvalaggio, Alessandro, primary, Pini, Lorenzo, additional, Gaiola, Matteo, additional, Velco, Aron, additional, Sansone, Giulio, additional, Anglani, Mariagiulia, additional, Fekonja, Lucius, additional, Chioffi, Franco, additional, Picht, Thomas, additional, Thiebaut de Schotten, Michel, additional, Zagonel, Vittorina, additional, Lombardi, Giuseppe, additional, D’Avella, Domenico, additional, and Corbetta, Maurizio, additional

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results