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A large variety of 1,2,3-thiadiazoles and 1,2,3-triazoles are used extensively in modern pure and applied organic chemistry as important structural blocks of numerous valuable products. Creation of new methods of synthesis of these isomeric compounds requires the development of reliable analytical tools to reveal the structural characteristics of these novel compounds, which are able to distinguish between isomers. Mass spectrometry (MS) is a clear choice for this task due to its selectivity, sensitivity, informational capacity, and reliability. Here, the application of electrospray ionization (ESI) with ion detection in positive and negative modes was demonstrated to be useful in structural studies. Additionally, interconversion of isomeric 4,5-functionalized 1,2,3-triazoles and 1,2,3-thiadiazoles was demonstrated. Application of accurate mass measurements and tandem mass spectrometry in MS2 and MS3 modes indicated the occurrence of gas-phase rearrangement of 1,2,3-triazoles into 1,2,3-thiadiazoles under (+)ESI-MS/MS conditions, independent of the nature of substituents, in line with the reaction in the condensed phase. Infrared multiple photon dissociation (IRMPD) spectroscopy enabled the establishment of structures of some of the most crucial common fragment ions, including [M+H-N 2 ] + and [M+H-N 2 -RSO 2 ] + species. The (-)ESI-MS/MS experiments were significantly more informative for the sulfonyl alkyl derivatives compared to the sulfonyl aryl ones. However, there was insufficient evidence to confirm the solution-phase transformation of 1,2,3-thiadiazoles into the corresponding 1,2,3-triazoles.

With the advent of technologies such as ion array detectors and high energy permanent magnet materials, there is renewed interest in the unique focusing properties of the cycloidal mass analyzer and its ability to enable small, high-resolution, and high-sensitivity instruments. However, most literature dealing with the design of cycloidal mass analyzers assumes a single channel detector because at the time of those publications, compatible multichannel detectors were not available. This manuscript introduces and discusses considerations and a procedure for designing cycloidal mass analyzers coupled with focal plane ion array detectors. To arrive at a set of relevant design considerations, we first review the unique focusing properties of the cycloidal mass analyzer and then present calculations detailing how the dimensions and position of the focal plane array detector relative to the ion source determine the possible mass ranges and resolutions of a cycloidal mass analyzer. We present derivations and calculations used to determine the volume of homogeneous electric and magnetic fields needed to contain the ion trajectories and explore the relationship between electric and magnetic field homogeneity on resolving power using finite element analysis (FEA) simulations. A set of equations relating the electric field homogeneity to the geometry of the electric sector electrodes was developed by fitting homogeneity values from 78 different FEA models. Finally, a sequence of steps is suggested for designing a cycloidal mass analyzer employing an array detector., (© 2022 John Wiley & Sons Ltd.)

In 1938, Walker Bleakney and John A. Hipple first described the cycloidal mass analyzer as the only mass analyzer configuration capable of "perfect" ion focusing. Why has their geometry been largely neglected for many years and how might it earn a respectable place in the world of modern chemical analysis? This Perspective explores the properties of the cycloidal mass analyzer and identifies the lack of suitable ion array detectors as a significant reason why cycloidal mass analyzers are not widely used. The recent development of capacitive transimpedance amplifier array detectors can enable several techniques using cycloidal mass analyzers including spatially coded apertures and single particle mass analysis with a "virtual-slit", helping the cycloidal mass analyzer earn a respectable place in chemical analysis.

A series of zinc-based catalysts was evaluated for their efficiency in decomposing formic acid into molecular hydrogen and carbon dioxide in the gas phase using quadrupole ion trap mass spectrometry experiments. The effectiveness of the catalysts in the series [(L)Zn(H)] + , where L=2,2':6',2''-terpyridine (tpy), 1,10-phenanthroline (phen) or 2,2'-bipyrydine (bpy), was found to depend on the ligand used, which turned out to be fundamental in tuning the catalytic properties of the zinc complex. Specifically, [(tpy)Zn(H)] + displayed the fastest reaction with formic acid proceeding by dehydrogenation to produce the zinc formate complex [(tpy)Zn(O 2 CH)] + and H 2 . The catalysts [(L)Zn(H)] + are reformed by decarboxylating the zinc formate complexes [(L)Zn(O 2 CH)] + by collision-induced dissociation, which is the only reaction channel for each of the ligands used. The decarboxylation reaction was found to be reversible, since the zinc hydride complexes [(L)Zn(H)] + react with carbon dioxide yielding the zinc formate complex. This reaction was again substantially faster for L=tpy than L=phen or bpy. The energetics and mechanisms of these processes were modelled using several levels of density functional theory (DFT) calculations. Experimental results are fully supported by the computational predictions., (© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Gas-phase C-C coupling reactions mediated by Ni (II) complexes were studied using a linear quadrupole ion trap mass spectrometer. Ternary nickel cationic carboxylate complexes, [(phen)Ni (OOCR 1 )] + (where phen = 1,10-phenanthroline), were formed by electrospray ionization. Upon collision-induced dissociation (CID), they extrude CO 2 forming the organometallic cation [(phen)Ni(R 1 )] + , which undergoes gas-phase ion-molecule reactions (IMR) with acetate esters CH 3 COOR 2 to yield the acetate complex [(phen)Ni (OOCCH 3 )] + and a C-C coupling product R 1 -R 2 . These Ni(II)/phenanthroline-mediated coupling reactions can be performed with a variety of carbon substituents R 1 and R 2 (sp 3 , sp 2 , or aromatic), some of them functionalized. Reaction rates do not seem to be strongly dependent on the nature of the substituents, as sp 3 -sp 3 or sp 2 -sp 2 coupling reactions proceed rapidly. Experimental results are supported by density functional theory calculations, which provide insights into the energetics associated with the C-C bond coupling step., (© 2019 John Wiley & Sons, Ltd.)

Two pseudohalide thiocyanate ions (SCN(-) ) have been used to replace two iodides in CH3 NH3 PbI3 , and the resulting perovskite material was used as the active material in solar cells. In accelerated stability tests, the CH3 NH3 Pb(SCN)2 I perovskite films were shown to be superior to the conventional CH3 NH3 PbI3 films as no significant degradation was observed after the film had been exposed to air with a relative humidity of 95 % for over four hours, whereas CH3 NH3 PbI3 films degraded in less than 1.5 hours. Solar cells based on CH3 NH3 Pb(SCN)2 I thin films exhibited an efficiency of 8.3 %, which is comparable to that of CH3 NH3 PbI3 based cells fabricated in the same way., (© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)