1. Pneumonia in patients with severe head injury: incidence, risk factors, and outcomes
- Author
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Kang Lu, Hao-Kuang Wang, Pi-Lien Tang, Han-Jung Chen, Po-Chou Liliang, Cheng-Loong Liang, Kuo-Wei Wang, Chun-Kai Huang, and Yu-Duan Tsai
- Subjects
medicine.medical_specialty ,business.industry ,Traumatic brain injury ,Incidence (epidemiology) ,Bacterial pneumonia ,Glasgow Coma Scale ,Retrospective cohort study ,medicine.disease ,Surgery ,Pneumonia ,Hemiparesis ,Internal medicine ,medicine ,medicine.symptom ,Risk factor ,business - Abstract
Object The reported incidence of hospital-acquired bacterial pneumonia in critically ill trauma patients varies from as low as 4% to as high as 87%, with fatality rates varying from 6% to 59%. Clinical studies have identified the risk factors for pneumonia. The authors undertook this retrospective study to evaluate the incidence, risk factors, and outcomes of hospital-acquired bacterial pneumonia in a group of patients with severe head injuries. Methods This was a retrospective review of consecutive adult patients admitted to the neurosurgical ICU in the authors' hospital because of severe head injury (Glasgow Coma Scale scores ≤ 8) between January 2008 and December 2010. Results During the study period, 290 patients were admitted to the neurosurgical ICU. Multivariate Cox regression analysis showed that age (HR 1.01, 95% CI 1.001–1.02), nasogastric tube insertion (HR 4.56, 95% CI 1.11–18.64), and hemiplegia or hemiparesis (HR 3.79, 95% CI 2.01–7.17) were significantly associated with the development of pneumonia. Conclusions The authors identified 3 risk factors (age, nasogastric tube insertion, and hemiplegia or hemiparesis) associated with the development of pneumonia in patients with severe head injury. This finding constituted the basis for developing a simple screening tool that can be used to assess the risk of occurrence of pneumonia in such patients.
- Published
- 2013
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