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5 results on '"Phuong Kim Bo"'

1. Correlation between the Lymphocyte-To-Monocyte Ratio (LMR) and Child–Pugh and MELD/MELDNa Scores in Vietnamese Patients with Liver Cirrhosis

Author

Diem Thi Nguyen, Nhan Huu Kha, Nhung Thi Hong Thai, Trang Diem Kha, Phuong Kim Bo, Khoa Tran Dang Dang, Hao Yen Tran, and Thang Nguyen

Subjects
liver cirrhosis, clinical, hematological, LMR, Child–Pugh, model for end-stage liver disease, Diseases of the digestive system. Gastroenterology, RC799-869
Abstract

Objectives: This study aims to determine cirrhotic patients’ clinical and laboratory characteristics, thereby examining the correlation between lymphocyte-to-monocyte ratio and Child–Pugh and MELD/MELDNa scores. Methods: A cross-sectional study with an analysis of 153 patients admitted to the Department of Gastroenterology–Clinical Hematology at Can Tho Central General Hospital. Data were collected via patient interviews and medical records. Results: The included patients were more likely to be male (66.7%) and were ≥60 years old (51.6%). Excessive alcohol consumption and hepatitis B were the dominant causes of cirrhosis (35.3% and 34.0%). The clinical and laboratory characteristics were similar to previous studies in cirrhotic patients. The mean Child score was 9.3 ± 2.1, including 9.8% of patients with Child A, 44.4% for Child B, and 45.8% for Child C. The mean MELD and MELDNa scores were 16.9 ± 7.1 and 19.4 ± 8.1, respectively. The mean lymphocyte-to-monocyte ratio (LMR) is 2.0 ± 2.2 (from 0.09 to 25.3), being negatively correlated with the other scores (Pearson correlation coefficients were −0.238; −0.211 and −0.245, respectively, all p-values < 0.01). Patients with LMR below 3.31 were more likely to be classified as Child–Pugh B and C. Conclusion: The correlation between LMR with Child–Pugh, MELD, and MELDNa scores was weak and negative.

Published
2022
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2. An External Validation Study of the Oakland and Glasgow-Blatchford Scores for Predicting Adverse Outcomes of Acute Lower Gastrointestinal Bleeding in an Asian Population

Author

Duc Trong Quach, Uyen Pham-Phuong Vo, Nguyet Thi-My Nguyen, Ly Thi-Kim Le, Minh-Cong Hong Vo, Phat Tan Ho, Tran Ngoc Nguyen, Phuong Kim Bo, Nam Hoai Nguyen, Khanh Truong Vu, Manh Van Dang, Minh Cao Dinh, Thai Quang Nguyen, Xung Van Nguyen, Suong Thi-Ngoc Le, and Chi Pham Tran

Subjects
Diseases of the digestive system. Gastroenterology, RC799-869
Abstract

Aims. This study is aimed at (1) validating the performance of Oakland and Glasgow-Blatchford (GBS) scores and (2) comparing these scores with the SALGIB score in predicting adverse outcomes of acute lower gastrointestinal bleeding (ALGIB) in a Vietnamese population. Methods. A multicenter cohort study was conducted on ALGIB patients admitted to seven hospitals across Vietnam. The adverse outcomes of ALGIB consisted of blood transfusion; endoscopic, radiologic, or surgical interventions; severe bleeding; and in-hospital death. The Oakland and GBS scores were calculated, and their performance was compared with that of SALGIB, a locally developed prediction score for adverse outcomes of ALGIB in Vietnamese, based on the data at admission. The accuracy of these scores was measured using the area under the receiver operating characteristic curve (AUC) and compared by the chi-squared test. Results. There were 414 patients with a median age of 60 (48–71). The rates of blood transfusion, hemostatic intervention, severe bleeding, and in-hospital death were 26.8%, 15.2%, 16.4, and 1.4%, respectively. The SALGIB score had comparable performance with the Oakland score (AUC: 0.81 and 0.81, respectively; p=0.631) and outperformed the GBS score (AUC: 0.81 and 0.76, respectively; p=0.002) for predicting the presence of any adverse outcomes of ALGIB. All of the three scores had acceptable and comparable performance for in-hospital death but poor performance for hemostatic intervention. The Oakland score had the best performance for predicting severe bleeding. Conclusions. The Oakland and SALGIB scores had excellent and comparable performance and outperformed the GBS score for predicting adverse outcomes of ALGIB in Vietnamese.

Published
2021
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3. An External Validation Study of the Oakland and Glasgow-Blatchford Scores for Predicting Adverse Outcomes of Acute Lower Gastrointestinal Bleeding in an Asian Population

Author

Manh Van Dang, Chi Pham Tran, Ly Thi-Kim Le, Khanh Truong Vu, Minh Cao Dinh, Nam Hoai Nguyen, Tran Ngoc Nguyen, Phat Tan Ho, Nguyet Thi-My Nguyen, Duc Trong Quach, Uyen Pham-Phuong Vo, Suong Thi-Ngoc Le, Minh-Cong Hong Vo, Phuong Kim Bo, Xung Van Nguyen, and Thai Quang Nguyen

Subjects
education.field_of_study, medicine.medical_specialty, Blood transfusion, Hepatology, Receiver operating characteristic, Article Subject, Adverse outcomes, business.industry, Vietnamese, medicine.medical_treatment, Population, Gastroenterology, External validation, RC799-869, Diseases of the digestive system. Gastroenterology, language.human_language, Acute lower gastrointestinal bleeding, Internal medicine, language, medicine, education, business, Research Article, Cohort study
Abstract

Aims. This study is aimed at (1) validating the performance of Oakland and Glasgow-Blatchford (GBS) scores and (2) comparing these scores with the SALGIB score in predicting adverse outcomes of acute lower gastrointestinal bleeding (ALGIB) in a Vietnamese population. Methods. A multicenter cohort study was conducted on ALGIB patients admitted to seven hospitals across Vietnam. The adverse outcomes of ALGIB consisted of blood transfusion; endoscopic, radiologic, or surgical interventions; severe bleeding; and in-hospital death. The Oakland and GBS scores were calculated, and their performance was compared with that of SALGIB, a locally developed prediction score for adverse outcomes of ALGIB in Vietnamese, based on the data at admission. The accuracy of these scores was measured using the area under the receiver operating characteristic curve (AUC) and compared by the chi-squared test. Results. There were 414 patients with a median age of 60 (48–71). The rates of blood transfusion, hemostatic intervention, severe bleeding, and in-hospital death were 26.8%, 15.2%, 16.4, and 1.4%, respectively. The SALGIB score had comparable performance with the Oakland score (AUC: 0.81 and 0.81, respectively; p = 0.631 ) and outperformed the GBS score (AUC: 0.81 and 0.76, respectively; p = 0.002 ) for predicting the presence of any adverse outcomes of ALGIB. All of the three scores had acceptable and comparable performance for in-hospital death but poor performance for hemostatic intervention. The Oakland score had the best performance for predicting severe bleeding. Conclusions. The Oakland and SALGIB scores had excellent and comparable performance and outperformed the GBS score for predicting adverse outcomes of ALGIB in Vietnamese.

Published
2021

4. Development and Validation of a Scoring System to Predict Severe Acute Lower Gastrointestinal Bleeding in Vietnamese

Author

Xung Van Nguyen, Uyen Pham-Phuong Vo, Thai Quang Nguyen, Nam Hoai Nguyen, Duc Trong Quach, Chi Pham Tran, Manh Van Dang, Tran Ngoc Nguyen, Khanh Truong Vu, Cong Hong-Minh Vo, Ly Thi-Kim Le, Phuong Kim Bo, Minh Cao Dinh, Phat Tan Ho, Nguyet Thi-My Nguyen, and Suong Thi-Ngoc Le

Subjects
Male, medicine.medical_specialty, Lower gastrointestinal bleeding, Physiology, Vietnamese, Colonoscopy, Blood Pressure, Lower Gastrointestinal Tract, macromolecular substances, Risk Assessment, Severity of Illness Index, 03 medical and health sciences, 0302 clinical medicine, Asian People, Heart Rate, Predictive Value of Tests, Risk Factors, Internal medicine, Medicine, Humans, Derivation, Prospective Studies, Prospective cohort study, Aged, Retrospective Studies, medicine.diagnostic_test, Receiver operating characteristic, business.industry, Platelet Count, Gastroenterology, Retrospective cohort study, Hepatology, Middle Aged, medicine.disease, language.human_language, Logistic Models, Hematocrit, ROC Curve, Vietnam, 030220 oncology & carcinogenesis, Area Under Curve, Acute Disease, language, 030211 gastroenterology & hepatology, Female, Symptom Assessment, business, Gastrointestinal Hemorrhage
Abstract

The prevalence of acute lower gastrointestinal bleeding (ALGIB) has progressively increased worldwide but there are few studies in Asian populations. This study aimed to develop and validate a scoring system to predict severe ALGIB in Vietnamese. Risk factors for severe ALGIB were identified by multiple logistic regression analysis using data from a retrospective cohort of 357 patients admitted to a tertiary hospital. These factors were weighted to develop the severe acute lower gastrointestinal bleeding (SALGIB) score to predict severe ALGIB. The performance of SALGIB was validated in a prospective cohort of 324 patients admitted to 6 other hospitals using area under the receiver operating characteristics curve (AUC) analysis. There were four factors at admission independently associated with severe ALGIB in the derivation cohort: heart rate ≥ 100/min, systolic blood pressure

Published
2020

5. Improving Efficacy of Endoscopic Diagnosis of Early Gastric Cancer: Gaps to Overcome from the Real-World Practice in Vietnam

Author

Minh Cao Dinh, Quy Nhuan Bui, Canh D Tran, Xung Van Nguyen, Nhan Q Le, Thai H Duong, Quy-Dung Dang Ho, Huy V Tran, Khien Van Vu, Duc Trong Quach, Tien T Dao, Phuong Kim Bo, Nguyen-Phuong N Tran, Khanh Truong Vu, and Huong M Duong

Subjects
Male, medicine.medical_specialty, Article Subject, Simethicone, Nationwide survey, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Stomach Neoplasms, Internal medicine, medicine, Humans, Endoscopy, Digestive System, Early Detection of Cancer, High prevalence, General Immunology and Microbiology, medicine.diagnostic_test, business.industry, Esophagogastroduodenoscopy, Cancer, General Medicine, Middle Aged, medicine.disease, Image Enhancement, Endoscopy, Early Gastric Cancer, Vietnam, 030220 oncology & carcinogenesis, Medicine, 030211 gastroenterology & hepatology, Female, business, medicine.drug, Research Article
Abstract

Objective. To identify factors associated with increased proportion of early gastric cancer to total detected gastric cancer among patients undergoing diagnostic esophagogastroduodenoscopy. Methods. A nationwide survey was conducted across 6 central-type and 6 municipal-type Vietnamese hospitals. A questionnaire regarding annual esophagogastroduodenoscopy volume, esophagogastroduodenoscopy preparation, the use of image-enhanced endoscopy, and number of gastric cancer diagnosed in 2018 was sent to each hospital. Results. The total proportion of early gastric cancer was 4.0% (115/2857). Routine preparation with simethicone and the use of image-enhanced endoscopy were associated with higher proportion of early gastric cancer (OR 1.9, 95% CI: 1.1–3.2, p=0.016; OR 2.7, 95% CI: 1.8–4.0, p<0.001, respectively). Esophagogastroduodenoscopies performed at central-type hospitals were associated with higher proportion of early gastric cancer (OR 1.9, 95% CI: 1.1–3.2, p=0.017). Esophagogastroduodenoscopies performed at hospitals with an annual volume of 30.000–60.000 were associated with higher proportion of early gastric cancer than those performed at hospitals with an annual volume of 10.000-p<0.001) and with a volume of >60.000–100.000 (OR 2.7, 95% CI: 1.7–4.2, p<0.001). Only four (33.3%) hospitals reported all endoscopic types of early gastric cancer. Conclusions. The detection of early gastric cancer is still challenging even for endoscopists working in regions with relatively high prevalence. The real-world evidence showed that endoscopic detection of early gastric cancer could potentially improve with simple adjustments of esophagogastroduodenoscopy protocols.

Published
2020
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